Dr Kenneth Rodgers

Senior Lecturer
Medicine, Central Clinical School
Heart Research Institute

Telephone +61 2 8208 8900
Fax +61 2 9565 5584

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Research interests

Heart disease and the cellular events that underlie the ageing process.

Selected grants

2010

  • Incorporation of levodopa into proteins in Parkinsons disease; Rodgers K; DVC Research/Bridging Support Grant.

2009

  • Stabilising atherosclerotic plaques using HDL apopliproteins; Rodgers K; DVC Research/Bridging Support Grant.

2008

  • Dako ACIS 111 Cellular Image Acquisition and Analysis System; Hambly B, Bao B, Bishop A, Black J, Campbell I, Dong Q, Gorrell M, Grau G, Hunt N, King N, Markham R, Marsh D, McDonald K, McLennan S, Rodgers K, Seth D; Australian Research Council (ARC)/Linkage Infrastructure, Equipment and Facilities (LIEF).

2005

  • Mechanisms of oxidised accumulation in ageing cells; Davies M, Rodgers K, Dean R; National Health and Medical Research Council (NHMRC)/Project Grants.

Selected publications

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Journals

  • Chan, S., Dunlop, R., Rowe, A., Double, K., Rodgers, K. (2012). L-DOPA is incorporated into brain proteins of patients treated for Parkinson's disease, inducing toxicity in human neuroblastoma cells in vitro. Experimental Neurology, 238(1), 29-37. [More Information]
  • Gracanin, M., Lam, M., Morgan, P., Rodgers, K., Hawkins, C., Davies, M. (2011). Amino acid, peptide, and protein hydroperoxides and their decomposition products modify the activity of the 26S proteasome. Free Radical Biology and Medicine, 50(2), 389-399. [More Information]
  • Reimers, G., Jackson, C., Rickards, J., Chan, P., Cohn, J., Rye, K., Barter, P., Rodgers, K. (2011). Inhibition of rupture of established atherosclerotic plaques by treatment with apolipoprotein A-I. Cardiovascular Research, 91(1), 37-44. [More Information]
  • Tang, J., Dunlop, R., Rowe, A., Rodgers, K., Ramzan, I. (2011). Kavalactones Yangonin and Methysticin Induce Apoptosis in Human Hepatocytes (HepG2) In Vitro. Phytotherapy Research, 25, 417-423. [More Information]
  • Dunlop, R., Brunk, U., Rodgers, K. (2011). Proteins containing oxidized amino acids induce apoptosis in human monocytes. The Biochemical Journal, 435(1), 207-216. [More Information]
  • Rodgers, K., Ford, J., Brunk, U. (2009). Heat shock proteins: keys to healthy ageing? Redox Report, 14(4), 147-153. [More Information]
  • Dunlop, R., Brunk, U., Rodgers, K. (2009). Oxidized proteins: mechanisms of removal and consequences of accumulation. IUBMB Life, 61(5), 522-527. [More Information]
  • Rodgers, K., Shiozawa, N. (2008). Misincorporation of amino acid analogues into proteins by biosynthesis. The International Journal of Biochemistry and Cell Biology, 40(8), 1452-1466. [More Information]
  • Dunlop, R., Dean, R., Rodgers, K. (2008). The impact of specific oxidized amino acids on protein turnover in J774 cells. Biochemical Journal, 410(1), 131-140. [More Information]
  • Zeng, J., DUNLOP, R., Rodgers, K., Davies, M. (2006). Evidence for inactivation of cysteine proteases by reactive carbonyls via glycation of active site thiols. Biochemical Journal, 398(2), 197-206. [More Information]
  • Rodgers, K., Hume, P., Morris, J., Dean, R. (2006). Evidence for L-dopa incorporation into cell proteins in patients treated with levodopa. Journal of Neurochemistry, 98(4), 1061-1067. [More Information]
  • Headlam, H., Gracanin, M., Rodgers, K., Davies, M. (2006). Inhibition of cathepsins and related proteases by amino acid, peptide, and protein hydroperoxides. Free Radical Biology and Medicine, 40(9), 1539-1548. [More Information]
  • Ozawa, K., Headlam, M., Mouradov, D., Watt, S., Beck, J., Rodgers, K., Dean, R., Huber, T., Otting, G., Dixon, N. (2005). Translational incorporation of L-3,4-dihydroxyphenylalanine into proteins. The FEBS Journal, 272(12), 3162-3171. [More Information]
  • Rodgers, K., Hume, P., Dunlop, R., Dean, R. (2004). Biosynthesis And Turnover Of DOPA-Containing Proteins By Human Cells. Free Radical Biology and Medicine, 37(11), 1756-1764. [More Information]
  • Rodgers, K., Dean, R. (2003). Assessment of proteasome activity in cell lysates and tissue homogenates using peptide substrates. The International Journal of Biochemistry and Cell Biology, 35(5), 716-727.

Conferences

  • Rodgers, K., DUNLOP, R., Dean, R. (2005). A novel approach to determine the pathways involved in the cellular catabolism of oxidised proteins. 13th Biennial Meeting of the Society for Free Radical Research, United Kingdom: Taylor and Francis.

2012

  • Chan, S., Dunlop, R., Rowe, A., Double, K., Rodgers, K. (2012). L-DOPA is incorporated into brain proteins of patients treated for Parkinson's disease, inducing toxicity in human neuroblastoma cells in vitro. Experimental Neurology, 238(1), 29-37. [More Information]

2011

  • Gracanin, M., Lam, M., Morgan, P., Rodgers, K., Hawkins, C., Davies, M. (2011). Amino acid, peptide, and protein hydroperoxides and their decomposition products modify the activity of the 26S proteasome. Free Radical Biology and Medicine, 50(2), 389-399. [More Information]
  • Reimers, G., Jackson, C., Rickards, J., Chan, P., Cohn, J., Rye, K., Barter, P., Rodgers, K. (2011). Inhibition of rupture of established atherosclerotic plaques by treatment with apolipoprotein A-I. Cardiovascular Research, 91(1), 37-44. [More Information]
  • Tang, J., Dunlop, R., Rowe, A., Rodgers, K., Ramzan, I. (2011). Kavalactones Yangonin and Methysticin Induce Apoptosis in Human Hepatocytes (HepG2) In Vitro. Phytotherapy Research, 25, 417-423. [More Information]
  • Dunlop, R., Brunk, U., Rodgers, K. (2011). Proteins containing oxidized amino acids induce apoptosis in human monocytes. The Biochemical Journal, 435(1), 207-216. [More Information]

2009

  • Rodgers, K., Ford, J., Brunk, U. (2009). Heat shock proteins: keys to healthy ageing? Redox Report, 14(4), 147-153. [More Information]
  • Dunlop, R., Brunk, U., Rodgers, K. (2009). Oxidized proteins: mechanisms of removal and consequences of accumulation. IUBMB Life, 61(5), 522-527. [More Information]

2008

  • Rodgers, K., Shiozawa, N. (2008). Misincorporation of amino acid analogues into proteins by biosynthesis. The International Journal of Biochemistry and Cell Biology, 40(8), 1452-1466. [More Information]
  • Dunlop, R., Dean, R., Rodgers, K. (2008). The impact of specific oxidized amino acids on protein turnover in J774 cells. Biochemical Journal, 410(1), 131-140. [More Information]

2006

  • Zeng, J., DUNLOP, R., Rodgers, K., Davies, M. (2006). Evidence for inactivation of cysteine proteases by reactive carbonyls via glycation of active site thiols. Biochemical Journal, 398(2), 197-206. [More Information]
  • Rodgers, K., Hume, P., Morris, J., Dean, R. (2006). Evidence for L-dopa incorporation into cell proteins in patients treated with levodopa. Journal of Neurochemistry, 98(4), 1061-1067. [More Information]
  • Headlam, H., Gracanin, M., Rodgers, K., Davies, M. (2006). Inhibition of cathepsins and related proteases by amino acid, peptide, and protein hydroperoxides. Free Radical Biology and Medicine, 40(9), 1539-1548. [More Information]

2005

  • Rodgers, K., DUNLOP, R., Dean, R. (2005). A novel approach to determine the pathways involved in the cellular catabolism of oxidised proteins. 13th Biennial Meeting of the Society for Free Radical Research, United Kingdom: Taylor and Francis.
  • Ozawa, K., Headlam, M., Mouradov, D., Watt, S., Beck, J., Rodgers, K., Dean, R., Huber, T., Otting, G., Dixon, N. (2005). Translational incorporation of L-3,4-dihydroxyphenylalanine into proteins. The FEBS Journal, 272(12), 3162-3171. [More Information]

2004

  • Rodgers, K., Hume, P., Dunlop, R., Dean, R. (2004). Biosynthesis And Turnover Of DOPA-Containing Proteins By Human Cells. Free Radical Biology and Medicine, 37(11), 1756-1764. [More Information]

2003

  • Rodgers, K., Dean, R. (2003). Assessment of proteasome activity in cell lysates and tissue homogenates using peptide substrates. The International Journal of Biochemistry and Cell Biology, 35(5), 716-727.

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