Dr Kirsten Morley

Senior Research Fellow
Addiction Medicine, NHMRC Centre of Research Excellence in Mental Health and Substance Use

Telephone +61 2 9515 3636
Fax +61 2 9515 8970

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Scholar website

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Biographical details

Dr Morley was awarded 2017 NHMRC TRIP Fellowship and a 2017 NSW Health mid-career translational research fellowship. She is a member of the NHMRC Centre of Research Excellence in Mental Health and Substance Use. She has 57 research publications: including 32 full length manuscripts with 20 first author publications in peer reviewed journals with ~ 1100 citations and 1 chapter in the Australian Alcohol Treatment Guidelines (2009); 34 presentations at local & international meetings; 1 nationally disseminated lecture series NSW Health Drug & Alcohol Medicine: Neurobiology of Addiction (2009).

Current grants 3 NHMRC Project grants as CI, 1 NSW Health Translational Research Grant Scheme.

Research interests

Subject Areas: Substance Use, Alcohol Use Disorder, Mental Health, Comorbidity, Treatment, Translation

Methodologies: Evaluation (Clinical Trials, Human laboratory studies), Neuroimaging, Pharmacoepidemiology, Implementation Science

Teaching and supervision

Lecture: Research Inquiry in the Masters of Neuroscience program for Brain and Mind Research Institute since 2012-present; Neuroadaptation 2014-present, Anti-craving Agents for Alcohol Dependence 2007-2010, 2014, Neurobiology of Addiction. ITAS tutor for Public Health.

Current projects

Clinical stream: pharmacogenetic prediction of topriamate in the treatment of alcohol use disorder (NHMRC funded), exploring neurobiological basis of the GABAb baclofen in the treatment of alcohol use disorder (NHMRC funded), neurocircuitry of emotional regulation in alcohol use disorder,exploring novel strategies in treatment of alcohol use disorder (private industry funded)

Translational stream: developing a shared care pathway for the treatment of alcohol dependence in primary care (NHMRC), improving management of comorbid mental health and substance use using an integrated approach (NSW Health), nationwise patterns of treatment utilisation

Selected grants

2017

  • Improving management of comorbid substance use and mental illness with an integrated and stepped care (ISC) approach; Morley K; NSW Health/Early Mid Career Fellowship.
  • A randomized controlled trial of oxytocin nasal spray for alcohol dependence; Guastella A, Haber P, Hermens D, Morley K, Lagopoulos J, Song C; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Low-intensity intervention: alcohol use and suicide attempt; Shand F, Morley K, Larsen M, Christensen H, Haber P, Chia J; DVC Research/Mental Health and Wellbeing scheme: Early Intervention and Prevention � Young People.

2016

  • Defining the clinical role of topiramate in the treatment of alcohol dependence in Australia; Haber P, Morley K, Teesson M, Kranzler H, Shanahan M, Trent R, Baillie A, Luquin N, Luquin N; National Health and Medical Research Council (NHMRC)/Project Grants.

2014

  • Clinical observation and comprehensive psychophysiological recording and behavioural coding equipment; Guastella A, de Rosnay M, Einfeld S, Glozier N, Hawes D, Hickie I, Lagapolos J, Matthews S, Menzies R, Morley K, Naismith S; National Health and Medical Research Council (NHMRC)/Equipment Grants.

2010

  • Models of Care in the Treatment of Dual Diagnosis: Alcohol Dependence & Sleep Disturbances; Morley K; National Health and Medical Research Council (NHMRC)/Travelling Award for Research Training.
  • The safety and efficacy of extended-release naltrexone: An Australian Pilot Study; Morley K, Haber P; Alcohol Education and Rehabilitation Foundation/Research Grant.

2008

  • Genetic Determinants of the response to pharmacotherapy for alcohol dependence; Morley K, Haber P; Health Administration Corporation/Drug and Alcohol Research Grant.

2006

  • Novel Strategies For The Treatment Of Alcohol Dependence; Morley K; National Health and Medical Research Council (NHMRC)/Early Career Fellowships.

Selected publications

Download citations: PDF RTF Endnote

Book Chapters

  • Haber, P., Lintzeris, N., Morley, K. (2009). Pharmacotherapies for alcohol dependence. In Paul Haber, Elizabeth Proude, Nick Lintzeris & Olga Lopatko (Eds.), Guidelines for the Treatment of Alcohol Problems, (pp. 93-106). Australia: Commonwealth of Australia.

Journals

  • Myers, C., Rego, J., Haber, P., Morley, K., Beck, K., Hogarth, L., Moustafa, A. (2017). Learning and generalization from reward and punishment in opioid addiction. Behavioural Brain Research, 317, 122-131. [More Information]
  • Morley, K., Cornish, J., Faingold, A., Wood, K., Haber, P. (2017). Pharmacotherapeutic agents in the treatment of methamphetamine dependence. Expert Opinion on Investigational Drugs, 26(5), 563-578. [More Information]
  • Morley, K., Logge, W., Pearson, S., Baillie, A., Haber, P. (2017). Socioeconomic and geographic disparities in access to pharmacotherapy for alcohol dependence. Journal of Substance Abuse Treatment, 74, 23-25. [More Information]
  • Freyer, C., Morley, K., Haber, P. (2016). Alcohol use disorders in Australia. Internal Medicine Journal, 46(11), 1259-1268. [More Information]
  • Morley, K., Baillie, A., Leung, S., Sannibale, C., Teesson, M., Haber, P. (2016). Is Specialized Integrated Treatment for Comorbid Anxiety, Depression and Alcohol Dependence Better than Treatment as Usual in a Public Hospital Setting? Alcohol and Alcoholism, 51(4), 402-409. [More Information]
  • Morley, K., Logge, W., Pearson, S., Baillie, A., Haber, P. (2016). National trends in alcohol pharmacotherapy: findings from an Australian claims database. Drug and Alcohol Dependence, 166, 254-257. [More Information]
  • Haber, P., Morley, K. (2016). The impact of alcohol pharmacotherapies on public health in Australia is limited by low prescribing rates. Public Health Research and Practice, 26(4), 1-4. [More Information]
  • Morley, K., Baillie, A., Leung, S., Addolorato, G., Leggio, L., Haber, P. (2014). Baclofen for the Treatment of Alcohol Dependence and Possible Role of Comorbid Anxiety. Alcohol and Alcoholism, 49(6), 654-660. [More Information]
  • Hunt, G., Siegfried, N., Morley, K., Sitharthan, T., Cleary, M. (2014). Psychosocial interventions for people with both severe mental illness and substance misuse. Schizophrenia Bulletin, 40(1), 18-20. [More Information]
  • Morley, K., Sitharthan, G., Haber, P., Tucker, P., Sitharthan, T. (2014). The Efficacy of an Opportunistic Cognitive Behavioral Intervention Package (OCB) on Substance Use and Comorbid Suicide Risk: A Multisite Randomized Controlled Trial. Journal of Consulting and Clinical Psychology, 82(1), 130-140. [More Information]
  • Morley, K., Baillie, A., Sannibale, C., Teesson, M., Haber, P. (2013). Integrated care for comorbid alcohol dependence and anxiety and/or depressive disorder: study protocol for an assessor-blind, randomized controlled trial. Addiction Science & Clinical Practice, 8, 1-8. [More Information]
  • Hunt, G., Siegfried, N., Morley, K., Sitharthan, T., Cleary, M. (2013). Psychosocial interventions for people with both severe mental illness and substance misuse. Cochrane Database of Systematic Reviews, 2013 (10), 1-258. [More Information]
  • Morley, K., Leung, S., Baillie, A., Haber, P. (2013). The efficacy and biobehavioural basis of baclofen in the treatment of alcoholic liver disease (BacALD): Study protocol for a randomised controlled trial. Contemporary Clinical Trials, 36(2), 348-355. [More Information]
  • Morley, K., Haber, P., Morgan, M., Samara, F. (2012). Pericyazine in the treatment of cannabis dependence in general practice: a naturalistic pilot trial. Substance Abuse and Rehabilitation, 3, 43-47. [More Information]
  • Morley, K., Teesson, M., Sannibale, C., Baillie, A., Haber, P. (2010). Clinical Predictors of Outcome from an Australian Pharmacological Relapse Prevention Trial. Alcohol and Alcoholism, 45, 520-526. [More Information]
  • Baillie, A., Stapinski, L., Crome, E., Morley, K., Sannibale, C., Haber, P., Teesson, M. (2010). Some new directions for research on psychological interventions for comorbid anxiety and substance use disorders. Drug and Alcohol Review, 29(5), 518-524. [More Information]
  • Colagiuri, B., Morley, K., Boakes, R., Haber, P. (2009). Expectancy in double-blind placebo-controlled trials: an example from alcohol dependence. Psychotherapy and Psychosomatics, 78(3), 167-171. [More Information]
  • Morley, K., Teesson, M., Sannibale, C., Haber, P. (2009). Sample bias from different recruitment strategies in a randomised controlled trial for alcohol dependence. Drug and Alcohol Review, 28(3), 222-229. [More Information]
  • Richardson, K., Baillie, A., Reid, S., Morley, K., Teesson, M., Sannibale, C., Weltman, M., Haber, P. (2008). Do acamprosate or naltrexone have an effect on daily drinking by reducing craving for alcohol? Addiction, 103(6), 953-959. [More Information]
  • Thomson, C., Morley, K., Teesson, M., Sannibale, C., Haber, P. (2008). Issues with recruitment to randomised controlled trials in the drug and alcohol field: a literature review and Australian case study. Drug and Alcohol Review, 27(2), 115-122. [More Information]
  • Richardson, K., Reid, S., Morley, K., Teesson, M., Sannibale, C., Weltman, M., Baillie, A., Haber, P. (2006). The effects of alcohol and naltrexone on craving and alcohol consumption. Alcoholism: Clinical and Experimental Research, 30(s2), 169A-169A.
  • Teesson, M., Morley, K., Reid, S., Sannibale, C., Thomson, C., Richardson, K., Haber, P. (2006). The influence of depression on pharmacotherapy for alcohol dependence. Alcoholism: Clinical and Experimental Research, 30(s2), 68A-68A.
  • Morley, K., Arnold, J., McGregor, I. (2005). Serotonin (1A) receptor involvement in acute 3,4-methylenedioxymethamphetamine (MDMA) facilitation of social interaction in the rat. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 29(5), 648-657. [More Information]
  • Morley, K., Li, K., Hunt, G., Mallet, P., McGregor, I. (2004). Cannabinoids Prevent The Acute Hyperthermia And Partially Protect Against The 5-Ht Depleting Effects Of Mdma ('Ecstasy') In Rats. Neuropharmacology, 46(7), 954-965. [More Information]
  • Morley, K., Cornish, J., Li, K., McGregor, I. (2004). Preexposure To Mdma ("Ecstasy") Delays Acquisition But Facilitates Mdma-Induced Reinstatement Of Amphetamine Self-Administration Behavior In Rats. Pharmacology, Biochemistry and Behavior, 79(2), 331-342. [More Information]
  • Cornish, J., Shahnawaz, Z., Thompson, M., Wong, S., Morley, K., Hunt, G., McGregor, I. (2003). Heat increases 3,4-methylenedioxymethamphetamine self-administration and social effects in rats. European Journal of Pharmacology, 482(1-3), 339-341. [More Information]
  • McGregor, I., Gurtman, C., Morley, K., Clemens, K., Li, K., Blokland, A., Cornish, J., Hunt, G. (2003). Increased anxiety and "depressive" symptoms months after MDMA ("ecstasy") in rats: drug-induced hyperthermia does not predict long-term outcomes. Psychopharmacology, 168(4), 465-474. [More Information]
  • Gallate, J., Morley, K., Ambermoon, P., McGregor, I. (2003). The consequences of beer consumption in rats: acute anxiolytic and ataxic effects and withdrawal-induced anxiety. Psychopharmacology, 166(1), 51-60. [More Information]
  • Gurtman, C., Morley, K., Li, K., Hunt, G., McGregor, I. (2002). Increased anxiety in rats after 3,4-methylenedioxymethamphetamine: association with serotonin depletion. European Journal of Pharmacology, 446(1-3), 89-96. [More Information]
  • Morley, K., Gallate, J., Hunt, G., McGregor, I., Mallet, P. (2001). Increased anxiety and impaired memory in rats 3 months after administration of 3,4-methylenedioxymethamphetamine ("Ecstasy"). European Journal of Pharmacology, 433(1), 91-99.

Conferences

  • Morley, K., Haber, P., Sitharthan, G., Tucker, P., Sitharthan, T. (2012). Clinical Predictors of Suicidal Behaviour Among Patients with Alcohol and/or Substance Abuse and Suicide Risk. APSAD Conference, Australasian Professional Society on Alcohol and other Drugs, Melbourne.

2017

  • Myers, C., Rego, J., Haber, P., Morley, K., Beck, K., Hogarth, L., Moustafa, A. (2017). Learning and generalization from reward and punishment in opioid addiction. Behavioural Brain Research, 317, 122-131. [More Information]
  • Morley, K., Cornish, J., Faingold, A., Wood, K., Haber, P. (2017). Pharmacotherapeutic agents in the treatment of methamphetamine dependence. Expert Opinion on Investigational Drugs, 26(5), 563-578. [More Information]
  • Morley, K., Logge, W., Pearson, S., Baillie, A., Haber, P. (2017). Socioeconomic and geographic disparities in access to pharmacotherapy for alcohol dependence. Journal of Substance Abuse Treatment, 74, 23-25. [More Information]

2016

  • Freyer, C., Morley, K., Haber, P. (2016). Alcohol use disorders in Australia. Internal Medicine Journal, 46(11), 1259-1268. [More Information]
  • Morley, K., Baillie, A., Leung, S., Sannibale, C., Teesson, M., Haber, P. (2016). Is Specialized Integrated Treatment for Comorbid Anxiety, Depression and Alcohol Dependence Better than Treatment as Usual in a Public Hospital Setting? Alcohol and Alcoholism, 51(4), 402-409. [More Information]
  • Morley, K., Logge, W., Pearson, S., Baillie, A., Haber, P. (2016). National trends in alcohol pharmacotherapy: findings from an Australian claims database. Drug and Alcohol Dependence, 166, 254-257. [More Information]
  • Haber, P., Morley, K. (2016). The impact of alcohol pharmacotherapies on public health in Australia is limited by low prescribing rates. Public Health Research and Practice, 26(4), 1-4. [More Information]

2014

  • Morley, K., Baillie, A., Leung, S., Addolorato, G., Leggio, L., Haber, P. (2014). Baclofen for the Treatment of Alcohol Dependence and Possible Role of Comorbid Anxiety. Alcohol and Alcoholism, 49(6), 654-660. [More Information]
  • Hunt, G., Siegfried, N., Morley, K., Sitharthan, T., Cleary, M. (2014). Psychosocial interventions for people with both severe mental illness and substance misuse. Schizophrenia Bulletin, 40(1), 18-20. [More Information]
  • Morley, K., Sitharthan, G., Haber, P., Tucker, P., Sitharthan, T. (2014). The Efficacy of an Opportunistic Cognitive Behavioral Intervention Package (OCB) on Substance Use and Comorbid Suicide Risk: A Multisite Randomized Controlled Trial. Journal of Consulting and Clinical Psychology, 82(1), 130-140. [More Information]

2013

  • Morley, K., Baillie, A., Sannibale, C., Teesson, M., Haber, P. (2013). Integrated care for comorbid alcohol dependence and anxiety and/or depressive disorder: study protocol for an assessor-blind, randomized controlled trial. Addiction Science & Clinical Practice, 8, 1-8. [More Information]
  • Hunt, G., Siegfried, N., Morley, K., Sitharthan, T., Cleary, M. (2013). Psychosocial interventions for people with both severe mental illness and substance misuse. Cochrane Database of Systematic Reviews, 2013 (10), 1-258. [More Information]
  • Morley, K., Leung, S., Baillie, A., Haber, P. (2013). The efficacy and biobehavioural basis of baclofen in the treatment of alcoholic liver disease (BacALD): Study protocol for a randomised controlled trial. Contemporary Clinical Trials, 36(2), 348-355. [More Information]

2012

  • Morley, K., Haber, P., Sitharthan, G., Tucker, P., Sitharthan, T. (2012). Clinical Predictors of Suicidal Behaviour Among Patients with Alcohol and/or Substance Abuse and Suicide Risk. APSAD Conference, Australasian Professional Society on Alcohol and other Drugs, Melbourne.
  • Morley, K., Haber, P., Morgan, M., Samara, F. (2012). Pericyazine in the treatment of cannabis dependence in general practice: a naturalistic pilot trial. Substance Abuse and Rehabilitation, 3, 43-47. [More Information]

2010

  • Morley, K., Teesson, M., Sannibale, C., Baillie, A., Haber, P. (2010). Clinical Predictors of Outcome from an Australian Pharmacological Relapse Prevention Trial. Alcohol and Alcoholism, 45, 520-526. [More Information]
  • Baillie, A., Stapinski, L., Crome, E., Morley, K., Sannibale, C., Haber, P., Teesson, M. (2010). Some new directions for research on psychological interventions for comorbid anxiety and substance use disorders. Drug and Alcohol Review, 29(5), 518-524. [More Information]

2009

  • Colagiuri, B., Morley, K., Boakes, R., Haber, P. (2009). Expectancy in double-blind placebo-controlled trials: an example from alcohol dependence. Psychotherapy and Psychosomatics, 78(3), 167-171. [More Information]
  • Haber, P., Lintzeris, N., Morley, K. (2009). Pharmacotherapies for alcohol dependence. In Paul Haber, Elizabeth Proude, Nick Lintzeris & Olga Lopatko (Eds.), Guidelines for the Treatment of Alcohol Problems, (pp. 93-106). Australia: Commonwealth of Australia.
  • Morley, K., Teesson, M., Sannibale, C., Haber, P. (2009). Sample bias from different recruitment strategies in a randomised controlled trial for alcohol dependence. Drug and Alcohol Review, 28(3), 222-229. [More Information]

2008

  • Richardson, K., Baillie, A., Reid, S., Morley, K., Teesson, M., Sannibale, C., Weltman, M., Haber, P. (2008). Do acamprosate or naltrexone have an effect on daily drinking by reducing craving for alcohol? Addiction, 103(6), 953-959. [More Information]
  • Thomson, C., Morley, K., Teesson, M., Sannibale, C., Haber, P. (2008). Issues with recruitment to randomised controlled trials in the drug and alcohol field: a literature review and Australian case study. Drug and Alcohol Review, 27(2), 115-122. [More Information]

2006

  • Richardson, K., Reid, S., Morley, K., Teesson, M., Sannibale, C., Weltman, M., Baillie, A., Haber, P. (2006). The effects of alcohol and naltrexone on craving and alcohol consumption. Alcoholism: Clinical and Experimental Research, 30(s2), 169A-169A.
  • Teesson, M., Morley, K., Reid, S., Sannibale, C., Thomson, C., Richardson, K., Haber, P. (2006). The influence of depression on pharmacotherapy for alcohol dependence. Alcoholism: Clinical and Experimental Research, 30(s2), 68A-68A.

2005

  • Morley, K., Arnold, J., McGregor, I. (2005). Serotonin (1A) receptor involvement in acute 3,4-methylenedioxymethamphetamine (MDMA) facilitation of social interaction in the rat. Progress in Neuro-Psychopharmacology and Biological Psychiatry, 29(5), 648-657. [More Information]

2004

  • Morley, K., Li, K., Hunt, G., Mallet, P., McGregor, I. (2004). Cannabinoids Prevent The Acute Hyperthermia And Partially Protect Against The 5-Ht Depleting Effects Of Mdma ('Ecstasy') In Rats. Neuropharmacology, 46(7), 954-965. [More Information]
  • Morley, K., Cornish, J., Li, K., McGregor, I. (2004). Preexposure To Mdma ("Ecstasy") Delays Acquisition But Facilitates Mdma-Induced Reinstatement Of Amphetamine Self-Administration Behavior In Rats. Pharmacology, Biochemistry and Behavior, 79(2), 331-342. [More Information]

2003

  • Cornish, J., Shahnawaz, Z., Thompson, M., Wong, S., Morley, K., Hunt, G., McGregor, I. (2003). Heat increases 3,4-methylenedioxymethamphetamine self-administration and social effects in rats. European Journal of Pharmacology, 482(1-3), 339-341. [More Information]
  • McGregor, I., Gurtman, C., Morley, K., Clemens, K., Li, K., Blokland, A., Cornish, J., Hunt, G. (2003). Increased anxiety and "depressive" symptoms months after MDMA ("ecstasy") in rats: drug-induced hyperthermia does not predict long-term outcomes. Psychopharmacology, 168(4), 465-474. [More Information]
  • Gallate, J., Morley, K., Ambermoon, P., McGregor, I. (2003). The consequences of beer consumption in rats: acute anxiolytic and ataxic effects and withdrawal-induced anxiety. Psychopharmacology, 166(1), 51-60. [More Information]

2002

  • Gurtman, C., Morley, K., Li, K., Hunt, G., McGregor, I. (2002). Increased anxiety in rats after 3,4-methylenedioxymethamphetamine: association with serotonin depletion. European Journal of Pharmacology, 446(1-3), 89-96. [More Information]

2001

  • Morley, K., Gallate, J., Hunt, G., McGregor, I., Mallet, P. (2001). Increased anxiety and impaired memory in rats 3 months after administration of 3,4-methylenedioxymethamphetamine ("Ecstasy"). European Journal of Pharmacology, 433(1), 91-99.

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