Dr Ling Zhu

Postdoc
Clincal Ophthalmology and Eye Health
Sydney Medical School

Telephone +61 2 9382 7289

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Selected grants

2015

  • Comparison of Müller cells isolated from the human macula and peripheral retina; Gillies M, Zhu L; Ophthalmic Research Institute of Australia (ORIA)/Research Grant.

2014

  • CLARIOstar Multifunctional Microplate Reader for Shared Used at the Open Access, Multi-User Molecular Biology Core Facility; Huang M, Scolyer R, Fraser S, Sahni S, Speranza T, Owens T, Barrs V, Ju Y, Kovacevic Z, Lu Z, Camp A, Slobedman B, Morris B, Oliver B, Dos Remedios C, Kalinowski D, Fu D, Lai D, Lovicu F, Allbutt H, Triccas J, Burgess J, Kril J, Dixon K, Rendina L, Byrne M, King N, Groundwater P, Williamson P, Ho J, Dong Q, Bao B, Assinder S, McLennan S, Richardson D, Ammit A, Sharland A, Hardikar A, Hong A, Hambly B, Lee C, Murphy C, Goldsbury C, Johnstone D, Lane D, Hibbs D, Joshua D, Huq F, Halliday G, Sutherland G, Zreiqat H, Lok H, Lyons G, Jansson P, Black J, Zhu L, Sunde M, Day M, Naylor M, Buckland M, Murray M, Shafie N, Lay P, Poronnik P, Codd R, Mason R, Ryan R, Christopherson R, de Graaf S; National Health and Medical Research Council (NHMRC)/Equipment Grants.

2013

  • QX100 Droplet Digital PCR system for Shared Used at the Open Access, Multi-User Molecular Biology Core Facility; Richardson D, Kril J, Murphy C, Vandenberg R, Rendina L, Dos Remedios C, Ju Y, Kovacevic Z, Lyons G, Sutherland G, Lay P, Ammit A, Lai D, Morris B, Day M, Dong Q, Bao B, Huang M, Camp A, Boyer M, Whittington R, Byrne M, Hanrahan J, Fu D, Jansson P, Lane D, Bagley E, Hibbs D, Zhang D, Fraser S, Scolyer R, Black J, Halliday G, Christie M, Zreiqat H, Murray M, Slobedman B, Naylor M, Burgess J, Triccas J, Mason R, Chadban S, Combes V, Lovicu F, McLennan S, Kalinowski D, Sharland A, Johnstone D, Groundwater P, Dixon K, Zhou F, Lovejoy D, Lu Z, Zhu L, Goldsbury C, Witting P, Buckland M, Assinder S, Purdie (Williams) A, Codd R, Owens T, Hambly B; National Health and Medical Research Council (NHMRC)/Equipment Grants.
  • The contribution of aberrant Wnt signalling to neuronal and vascular pathology in retinal disease; Gillies M, Shen W, McAvoy J, Zhu L; National Health and Medical Research Council (NHMRC)/Project Grants.

2012

  • Neuroprotection and anti-angiogenic therapy using a novel transgenic model; Shen W, Zhu L; Ophthalmic Research Institute of Australia (ORIA)/Research Grant.

Selected publications

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Journals

  • Barthelmes, D., Zhu, L., Shen, W., Gillies, M., Irhimeh, M. (2014). Differential gene expression in Lin-/VEGF-R2+ bone marrow-derived endothelial progenitor cells isolated from diabetic mice. Cardiovascular Diabetology, 13(1), 1-10. [More Information]
  • Shen, W., Lee, S., Araujo, J., Chung, S., Zhu, L., Gillies, M. (2014). Effect of glucocorticoids on neuronal and vascular pathology in a transgenic model of selective Muller cell ablation. Glia, 62(7), 1110-1124. [More Information]
  • Wang, K., Zhou, F., Zhu, L., Zhu, X., Zhang, K., Zhu, L. (2014). High level soluble expression, purification, and characterization of human ciliary neruonotrophic factor in Escherichia coli by single protein production system. Protein Expression and Purification, 96, 8-13. [More Information]
  • Li, Z., Cheung, F., Zheng, J., Chan, T., Zhu, L., Zhou, F. (2014). Interaction of the Bioactive Flavonol, Icariin, with the Essential Human Solute Carrier Transporters. Journal of Biochemical and Molecular Toxicology (Online), 28(2), 91-97. [More Information]
  • Wang, K., Zhou, F., Zhu, X., Zhang, K., Huang, B., Zhu, L., Zhu, L. (2014). Neuroprotective properties of ciliary neurotrophic factor on retinoic acid (RA)-predifferentiated SH-SY5Y neuroblastoma cells. Folia Neuropathologica, 52(2), 121-127. [More Information]
  • Zheng, J., Chan, T., Cheung, F., Zhu, L., Murray, M., Zhou, F. (2014). PDZK1 and NHERF1 regulate the function of human organic anion transporting polypeptide 1A2 (OATP1A2) by modulating its subcellular trafficking and stability. PLoS One, 9(4), 1-11. [More Information]
  • Wang, K., Zhu, L., Zhu, X., Zhang, K., Huang, B., Zhang, J., Zhang, Y., Zhu, L., Zhou, B., Zhou, F. (2014). Protective Effect of Paeoniflorin on AB 25-35- Induced SH-SY5Y Cell Injury by Preventing Mitochondrial Dysfunction. Cellular and Molecular Neurobiology, 34(2), 227-234. [More Information]
  • Wang, K., Zhang, K., Lv, Z., Zhu, X., Zhu, L., Zhou, F. (2014). Ultrasensitive detection of microRNA with isothermal amplification and a time-resolved fluorescence sensor. Biosensors and Bioelectronics, 57, 91-95. [More Information]
  • Zhu, X., Wang, K., Zhang, K., Zhu, L., Zhou, F. (2014). Ziyuglycoside II induces cell cycle arrest and apoptosis through activation of ROS/JNK pathway in human breast cancer cells. Toxicology Letters, 227(1), 65-73. [More Information]
  • Zhu, L., Shen, W., Zhu, M., Coorey, N., Nguyen, A., Barthelmes, D., Gillies, M. (2013). Anti-Retinal Antibodies in Patients With Macular Telangiectasia Type 2. Investigative Ophthalmology and Visual Science, 54(8), 5675-5683. [More Information]
  • Barthelmes, D., Irhimeh, M., Gillies, M., Karimipour, M., Zhou, M., Zhu, L., Shen, W. (2013). Diabetes impairs mobilization of mouse bone marrow-derived Lin−/VEGF-R2+ progenitor cells. Blood Cells, Molecules and Diseases, 51(3), 163-173. [More Information]
  • Zhou, F., Zheng, J., Zhu, L., Jodal, A., Cui, P., Wong, K., Gurney, H., Church, W., Murray, M. (2013). Functional Analysis of Novel Polymorphisms in the Human SLCO1A2 Gene that Encodes the Transporter OATP1A2. The AAPS Journal, 15(4), 1099-1108. [More Information]
  • Chan, T., Li, Z., Zheng, J., Cheung, F., Zhu, L., Zhou, F. (2013). Inhibitory effects of apigenin and kaempferol on the essential solute carrier transporters. World Journal of Pharmacology, 2(4), 115-121. [More Information]
  • Shen, W., Zhu, L., Lee, S., Chung, S., Gillies, M. (2013). Involvement of NT3 and P75NTR in photoreceptor degeneration following selective Muller cell ablation. Journal of Neuroinflammation, 10(137), 1-13. [More Information]
  • Barthelmes, D., Irhimeh, M., Gillies, M., Zhu, L., Shen, W. (2013). Isolation and characterization of mouse bone marrow-derived Lin−/VEGF-R2+ progenitor cells. Annals of Hematology, 92(11), 1461-1472. [More Information]
  • Xu, F., Li, Z., Zheng, J., Cheung, F., Chan, T., Zhu, L., Zhuge, H., Zhou, F. (2013). The Inhibitory Effects of the Bioactive Components Isolated from Scutellaria Baicalensis on the Cellular Uptake Mediated by the Essential Solute Carrier Transporters. Journal of Pharmaceutical Sciences, 102(11), 4205-4211. [More Information]
  • Shen, W., Fruttiger, M., Zhu, L., Chung, S., Barnett, N., Kirk, J., Lee, S., Coorey, N., Killingsworth, M., Sherman, L., Gillies, M. (2012). Conditional Muller Cell Ablation Causes Independent Neuronal and Vascular Pathologies in a Novel Transgenic Model. The Journal of Neuroscience, 32(45), 15715-15727. [More Information]
  • Zhou, F., Li, Z., Lam, P., Zhu, L., Wang, K. (2012). Current Updates in the Genetic Polymorphisms of Human Organic Anion Transporters (OATs). Journal of Pharmacogenomics & Pharmacoproteomics, 3(6), 1-8. [More Information]
  • Len, A., Powner, M., Zhu, L., Hageman, G., Song, X., Fruttiger, M., Gillies, M. (2012). Pilot application of iTRAQ to the retinal disease macular telangiectasia. Journal of Proteome Research, 11(2), 537-553. [More Information]
  • Coorey, N., Shen, W., Chung, S., Zhu, L., Gillies, M. (2012). The role of glia in retinal vascular disease. Clinical & Experimental Optometry, 95(3), 266-281. [More Information]
  • Irhimeh, M., Shen, W., Chung, S., Zhu, L., Barthelmes, D., Gillies, M. (2011). Erythropoetin treatment recruits pECFCs from the marrow into the blood and stabilizes retinal vasculature. Experimental Hematology, 39(8), S77-S78.
  • Len, A., Powner, M., Zhu, L., Hageman, G., Song, X., Fruttiger, M., Gillies, M. (2011). Pilot Application of iTRAQ to the Retinal Disease Macular Telangiectasia. Journal of Proteome Research, 11(2), 537-553. [More Information]
  • Zhou, F., Lee, A., Krafczyk, K., Zhu, L., Murray, M. (2011). Protein Kinase C Regulates the Internalization and Function of the Human Organic Anion Transporting Polypeptide 1A2. British Journal of Pharmacology, 162(6), 1380-1388. [More Information]
  • Shen, W., Li, S., Chung, S., Zhu, L., Stayt, J., Su, T., Couraud, P., Romero, I., Weksler, B., Gillies, M. (2011). Tyrosine phosphorylation of VE-cadherin and claudin-5 is associated with TGF-β1-induced permeability of centrally derived vascular endothelium. European Journal of Cell Biology, 90(4), 323-332. [More Information]
  • Zhou, F., Zhu, L., Cui, P., Church, W., Murray, M. (2010). Functional characterization of nonsynonymous single nucleotide polymorphisms in the human organic anion transporter 4 (hOAT4). British Journal of Pharmacology, 159, 419-427. [More Information]

2014

  • Barthelmes, D., Zhu, L., Shen, W., Gillies, M., Irhimeh, M. (2014). Differential gene expression in Lin-/VEGF-R2+ bone marrow-derived endothelial progenitor cells isolated from diabetic mice. Cardiovascular Diabetology, 13(1), 1-10. [More Information]
  • Shen, W., Lee, S., Araujo, J., Chung, S., Zhu, L., Gillies, M. (2014). Effect of glucocorticoids on neuronal and vascular pathology in a transgenic model of selective Muller cell ablation. Glia, 62(7), 1110-1124. [More Information]
  • Wang, K., Zhou, F., Zhu, L., Zhu, X., Zhang, K., Zhu, L. (2014). High level soluble expression, purification, and characterization of human ciliary neruonotrophic factor in Escherichia coli by single protein production system. Protein Expression and Purification, 96, 8-13. [More Information]
  • Li, Z., Cheung, F., Zheng, J., Chan, T., Zhu, L., Zhou, F. (2014). Interaction of the Bioactive Flavonol, Icariin, with the Essential Human Solute Carrier Transporters. Journal of Biochemical and Molecular Toxicology (Online), 28(2), 91-97. [More Information]
  • Wang, K., Zhou, F., Zhu, X., Zhang, K., Huang, B., Zhu, L., Zhu, L. (2014). Neuroprotective properties of ciliary neurotrophic factor on retinoic acid (RA)-predifferentiated SH-SY5Y neuroblastoma cells. Folia Neuropathologica, 52(2), 121-127. [More Information]
  • Zheng, J., Chan, T., Cheung, F., Zhu, L., Murray, M., Zhou, F. (2014). PDZK1 and NHERF1 regulate the function of human organic anion transporting polypeptide 1A2 (OATP1A2) by modulating its subcellular trafficking and stability. PLoS One, 9(4), 1-11. [More Information]
  • Wang, K., Zhu, L., Zhu, X., Zhang, K., Huang, B., Zhang, J., Zhang, Y., Zhu, L., Zhou, B., Zhou, F. (2014). Protective Effect of Paeoniflorin on AB 25-35- Induced SH-SY5Y Cell Injury by Preventing Mitochondrial Dysfunction. Cellular and Molecular Neurobiology, 34(2), 227-234. [More Information]
  • Wang, K., Zhang, K., Lv, Z., Zhu, X., Zhu, L., Zhou, F. (2014). Ultrasensitive detection of microRNA with isothermal amplification and a time-resolved fluorescence sensor. Biosensors and Bioelectronics, 57, 91-95. [More Information]
  • Zhu, X., Wang, K., Zhang, K., Zhu, L., Zhou, F. (2014). Ziyuglycoside II induces cell cycle arrest and apoptosis through activation of ROS/JNK pathway in human breast cancer cells. Toxicology Letters, 227(1), 65-73. [More Information]

2013

  • Zhu, L., Shen, W., Zhu, M., Coorey, N., Nguyen, A., Barthelmes, D., Gillies, M. (2013). Anti-Retinal Antibodies in Patients With Macular Telangiectasia Type 2. Investigative Ophthalmology and Visual Science, 54(8), 5675-5683. [More Information]
  • Barthelmes, D., Irhimeh, M., Gillies, M., Karimipour, M., Zhou, M., Zhu, L., Shen, W. (2013). Diabetes impairs mobilization of mouse bone marrow-derived Lin−/VEGF-R2+ progenitor cells. Blood Cells, Molecules and Diseases, 51(3), 163-173. [More Information]
  • Zhou, F., Zheng, J., Zhu, L., Jodal, A., Cui, P., Wong, K., Gurney, H., Church, W., Murray, M. (2013). Functional Analysis of Novel Polymorphisms in the Human SLCO1A2 Gene that Encodes the Transporter OATP1A2. The AAPS Journal, 15(4), 1099-1108. [More Information]
  • Chan, T., Li, Z., Zheng, J., Cheung, F., Zhu, L., Zhou, F. (2013). Inhibitory effects of apigenin and kaempferol on the essential solute carrier transporters. World Journal of Pharmacology, 2(4), 115-121. [More Information]
  • Shen, W., Zhu, L., Lee, S., Chung, S., Gillies, M. (2013). Involvement of NT3 and P75NTR in photoreceptor degeneration following selective Muller cell ablation. Journal of Neuroinflammation, 10(137), 1-13. [More Information]
  • Barthelmes, D., Irhimeh, M., Gillies, M., Zhu, L., Shen, W. (2013). Isolation and characterization of mouse bone marrow-derived Lin−/VEGF-R2+ progenitor cells. Annals of Hematology, 92(11), 1461-1472. [More Information]
  • Xu, F., Li, Z., Zheng, J., Cheung, F., Chan, T., Zhu, L., Zhuge, H., Zhou, F. (2013). The Inhibitory Effects of the Bioactive Components Isolated from Scutellaria Baicalensis on the Cellular Uptake Mediated by the Essential Solute Carrier Transporters. Journal of Pharmaceutical Sciences, 102(11), 4205-4211. [More Information]

2012

  • Shen, W., Fruttiger, M., Zhu, L., Chung, S., Barnett, N., Kirk, J., Lee, S., Coorey, N., Killingsworth, M., Sherman, L., Gillies, M. (2012). Conditional Muller Cell Ablation Causes Independent Neuronal and Vascular Pathologies in a Novel Transgenic Model. The Journal of Neuroscience, 32(45), 15715-15727. [More Information]
  • Zhou, F., Li, Z., Lam, P., Zhu, L., Wang, K. (2012). Current Updates in the Genetic Polymorphisms of Human Organic Anion Transporters (OATs). Journal of Pharmacogenomics & Pharmacoproteomics, 3(6), 1-8. [More Information]
  • Len, A., Powner, M., Zhu, L., Hageman, G., Song, X., Fruttiger, M., Gillies, M. (2012). Pilot application of iTRAQ to the retinal disease macular telangiectasia. Journal of Proteome Research, 11(2), 537-553. [More Information]
  • Coorey, N., Shen, W., Chung, S., Zhu, L., Gillies, M. (2012). The role of glia in retinal vascular disease. Clinical & Experimental Optometry, 95(3), 266-281. [More Information]

2011

  • Irhimeh, M., Shen, W., Chung, S., Zhu, L., Barthelmes, D., Gillies, M. (2011). Erythropoetin treatment recruits pECFCs from the marrow into the blood and stabilizes retinal vasculature. Experimental Hematology, 39(8), S77-S78.
  • Len, A., Powner, M., Zhu, L., Hageman, G., Song, X., Fruttiger, M., Gillies, M. (2011). Pilot Application of iTRAQ to the Retinal Disease Macular Telangiectasia. Journal of Proteome Research, 11(2), 537-553. [More Information]
  • Zhou, F., Lee, A., Krafczyk, K., Zhu, L., Murray, M. (2011). Protein Kinase C Regulates the Internalization and Function of the Human Organic Anion Transporting Polypeptide 1A2. British Journal of Pharmacology, 162(6), 1380-1388. [More Information]
  • Shen, W., Li, S., Chung, S., Zhu, L., Stayt, J., Su, T., Couraud, P., Romero, I., Weksler, B., Gillies, M. (2011). Tyrosine phosphorylation of VE-cadherin and claudin-5 is associated with TGF-β1-induced permeability of centrally derived vascular endothelium. European Journal of Cell Biology, 90(4), 323-332. [More Information]

2010

  • Zhou, F., Zhu, L., Cui, P., Church, W., Murray, M. (2010). Functional characterization of nonsynonymous single nucleotide polymorphisms in the human organic anion transporter 4 (hOAT4). British Journal of Pharmacology, 159, 419-427. [More Information]

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