Dr Lucy Dawes

Post Doctoral Researcher
Save Sight Institute, Sydney Medical School

Telephone +61 2 9382 7300

Map

Selected grants

2014

  • Secreted frizzled related protein 1 (SFRP1) and Keratoconus; You J, Sutton G, Dawes L; Ophthalmic Research Institute of Australia (ORIA)/Research Grants.

2011

  • Support for a 12 month Postdoctoral Fellowship ($106,745) for Dr Lucy Dawes to supplement her Endeavour Postdoctoral award from the Department of Education, Science and Training; McAvoy J, Dawes L; Sydney Eye Hospital Foundation/Research Support.

Selected publications

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Journals

  • Dawes, L., Sugiyama, Y., Lovicu, F., Harris, C., Shelley, E., McAvoy, J. (2014). Interactions between lens epithelial and fiber cells reveal an intrinsic self-assembly mechanism. Developmental Biology, 385(2), 291-303. [More Information]
  • Dawes, L., Duncan, G., Wormstone, I. (2013). Age-Related Differences in Signaling Efficiency of Human Lens Cells Underpin Differential Wound Healing Response Rates following Cataract Surgery. Investigative Ophthalmology and Visual Science, 54(1), 333-342. [More Information]
  • Wang, C., Dawes, L., Liu, Y., Wen, L., Lovicu, F., McAvoy, J. (2013). Dexamethasone influences fgf-induced responses in lens epithelial explants and promotes the posterior capsule coverage that is a feature of glucocorticoid-induced cataract. Experimental Eye Research, 111, 79-87. [More Information]
  • Dawes, L., Sugiyama, Y., Tanedo, A., Lovicu, F., McAvoy, J. (2013). Wnt-Frizzled signaling is part of an FGF-induced cascade that promotes lens fiber differentiation. Investigative Ophthalmology and Visual Science, 54(3), 1582-1590. [More Information]
  • Dawes, L., Illingworth, C., Wormstone, I. (2012). A fully human in vitro capsular bag model to permit intraocular lens evaluation. Investigative Ophthalmology and Visual Science, 53(1), 23-29. [More Information]
  • Eldred, J., Dawes, L., Wormstone, I. (2011). The lens as a model for fibrotic disease. Proceedings of the Royal Society of London. B Biological Sciences, 366(1568), 1301-1319. [More Information]
  • Dawes, L., Sleeman, M., Anderson, I., Reddan, J., Wormstone, I. (2009). TGFbeta/Smad4-dependent and -independent regulation of human lens epithelial cells. Investigative Ophthalmology and Visual Science, 50(11), 5318-5327. [More Information]
  • Dawes, L., Eldred, J., Anderson, I., Sleeman, M., Reddan, J., Duncan, G., Wormstone, I. (2008). TGF beta-induced contraction is not promoted by fibronectin-fibronectin receptor interaction, or alpha SMA expression. Investigative Ophthalmology and Visual Science, 49(2), 650-661. [More Information]
  • Dawes, L., Elliot, R., Reddan, J., Wormstone, Y., Wormstone, I. (2007). Oligonucleotide microarray analysis of human lens epithelial cells: TGFbeta regulated gene expression. Molecular Vision, 13, 1181-1197. [More Information]
  • Dawes, L., Angell, H., Sleeman, M., Reddan, J., Wormstone, I. (2007). TGFbeta isoform dependent Smad2/3 kinetics in human lens epithelial cells: a Cellomics analysis. Experimental Eye Research, 84(5), 1009-1012. [More Information]
  • Grocott, T., Frost, V., Maillard, M., Johansen, T., Wheeler, G., Dawes, L., Wormstone, I., Chantry, A. (2007). The MH1 domain of Smad3 interacts with Pax6 and represses autoregulation of the Pax6 P1 promoter. Nucleic Acids Research, 35(3), 890-901. [More Information]
  • Wormstone, I., Anderson, I., Eldred, J., Dawes, L., Duncan, G. (2006). Short-term exposure to transforming growth factor beta induces long-term fibrotic responses. Experimental Eye Research, 83(5), 1238-1245. [More Information]

2014

  • Dawes, L., Sugiyama, Y., Lovicu, F., Harris, C., Shelley, E., McAvoy, J. (2014). Interactions between lens epithelial and fiber cells reveal an intrinsic self-assembly mechanism. Developmental Biology, 385(2), 291-303. [More Information]

2013

  • Dawes, L., Duncan, G., Wormstone, I. (2013). Age-Related Differences in Signaling Efficiency of Human Lens Cells Underpin Differential Wound Healing Response Rates following Cataract Surgery. Investigative Ophthalmology and Visual Science, 54(1), 333-342. [More Information]
  • Wang, C., Dawes, L., Liu, Y., Wen, L., Lovicu, F., McAvoy, J. (2013). Dexamethasone influences fgf-induced responses in lens epithelial explants and promotes the posterior capsule coverage that is a feature of glucocorticoid-induced cataract. Experimental Eye Research, 111, 79-87. [More Information]
  • Dawes, L., Sugiyama, Y., Tanedo, A., Lovicu, F., McAvoy, J. (2013). Wnt-Frizzled signaling is part of an FGF-induced cascade that promotes lens fiber differentiation. Investigative Ophthalmology and Visual Science, 54(3), 1582-1590. [More Information]

2012

  • Dawes, L., Illingworth, C., Wormstone, I. (2012). A fully human in vitro capsular bag model to permit intraocular lens evaluation. Investigative Ophthalmology and Visual Science, 53(1), 23-29. [More Information]

2011

  • Eldred, J., Dawes, L., Wormstone, I. (2011). The lens as a model for fibrotic disease. Proceedings of the Royal Society of London. B Biological Sciences, 366(1568), 1301-1319. [More Information]

2009

  • Dawes, L., Sleeman, M., Anderson, I., Reddan, J., Wormstone, I. (2009). TGFbeta/Smad4-dependent and -independent regulation of human lens epithelial cells. Investigative Ophthalmology and Visual Science, 50(11), 5318-5327. [More Information]

2008

  • Dawes, L., Eldred, J., Anderson, I., Sleeman, M., Reddan, J., Duncan, G., Wormstone, I. (2008). TGF beta-induced contraction is not promoted by fibronectin-fibronectin receptor interaction, or alpha SMA expression. Investigative Ophthalmology and Visual Science, 49(2), 650-661. [More Information]

2007

  • Dawes, L., Elliot, R., Reddan, J., Wormstone, Y., Wormstone, I. (2007). Oligonucleotide microarray analysis of human lens epithelial cells: TGFbeta regulated gene expression. Molecular Vision, 13, 1181-1197. [More Information]
  • Dawes, L., Angell, H., Sleeman, M., Reddan, J., Wormstone, I. (2007). TGFbeta isoform dependent Smad2/3 kinetics in human lens epithelial cells: a Cellomics analysis. Experimental Eye Research, 84(5), 1009-1012. [More Information]
  • Grocott, T., Frost, V., Maillard, M., Johansen, T., Wheeler, G., Dawes, L., Wormstone, I., Chantry, A. (2007). The MH1 domain of Smad3 interacts with Pax6 and represses autoregulation of the Pax6 P1 promoter. Nucleic Acids Research, 35(3), 890-901. [More Information]

2006

  • Wormstone, I., Anderson, I., Eldred, J., Dawes, L., Duncan, G. (2006). Short-term exposure to transforming growth factor beta induces long-term fibrotic responses. Experimental Eye Research, 83(5), 1238-1245. [More Information]

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