Dr Maaike Kockx

Senior Research Fellow
ANZAC Research Institute, Concord Clinical School

Telephone +61297679826
Fax +61297679101

Map

Selected grants

2014

  • EVOSĀ® FL Auto cell imaging system; Nicholson G, Clark G, Zhou H, Jessup W, Le Couteur D, McMahon A, McLachlan A, Allan C, Handelsman D, Hart D, Walters K, Kritharides L, Kockx M, Kennerson M, Cooper M, Seibel M, Verma N, Silveira P, Fromm P, Simanainen U, Cogger V, Zheng Y; National Health and Medical Research Council (NHMRC)/Equipment Grants.

2013

  • IVIS Lumina II in vivo Imaging System; Seibel M, Handelsman D, Le Couteur D, Hart D, Nicholson G, Freedman B, Kritharides L, Jessup W, Zhou H, Clark G, Kennerson M, Allan C, Walters K, Cogger V, McMahon A, Simanainen U, Kockx M, Speranza T, Zheng Y; DVC Research/Equipment Grant.

Selected publications

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Book Chapters

  • Kockx, M., Kritharides, L. (2012). Cyclosporin A-Induced Hyperlipidemia. In Sasa Frank and Gerhard Kostner (Eds.), Lipoproteins- Role in Health and Diseases, (pp. 337-354). Croatia: InTech Publishers.

Journals

  • Kockx, M., Jessup, W., Kritharides, L. (2013). Getting to the 'guts' of the matter: intestinal control of lipid metabolism. Current Opinion in Lipidology, 24(1), 105-106. [More Information]
  • Karunakaran, D., Kockx, M., Owen, D., Burnett, J., Jessup, W., Kritharides, L. (2013). Protein Kinase C Controls Vesicular Transport and Secretion of Apolipoprotein E from Primary Human Macrophages. The Journal of Biological Chemistry, 288(7), 5186-5197. [More Information]
  • Kockx, M., Dinnes, D., Huang, K., Sharpe, L., Jessup, W., Brown, A., Kritharides, L. (2012). Cholesterol accumulation inhibits ER to Golgi transport and protein secretion: studies of apolipoprotein E and VSVGt. The Biochemical Journal, 447(1), 51-60. [More Information]
  • Gelissen, I., Sharpe, L., Sandoval, C., Rao, G., Kockx, M., Kritharides, L., Jessup, W., Brown, A. (2012). Protein kinase A modulates the activity of a major human isoform of ABCG1. Journal of Lipid Research, 53(10), 2133-2140. [More Information]
  • Kockx, M., Jessup, W., Kritharides, L. (2010). Cyclosporin A and atherosclerosis - Cellular pathways in atherogenesis. Pharmacology and Therapeutics, 128(1), 106-118. [More Information]
  • Lee, Y., Kockx, M., Raftery, M., Jessup, W., Griffith, R., Kritharides, L. (2010). Glycosylation and Sialylation of Macrophage-derived Human Apolipoprotein E Analyzed by SDS-PAGE and Mass Spectrometry: Evidence for a Novel Site of Glycosylation on SER290. Molecular and Cellular Proteomics, 9(9), 1968-1981. [More Information]
  • Kockx, M., Guo, D., Traini, M., Gaus, K., Kay, J., Wimmer-Kleikamp, S., Rentero, C., Burnett, J., Le Goff, W., van Eck, M., Kritharides, L., et al (2009). Cyclosporin A decreases apolipoprotein E secretion from human macrophages via a protein phosphatase2B-dependent and ATP-binding cassette transporter A1 (ABCA1)-independent pathway. Journal of Biological Chemistry, 284(36), 24144-24154. [More Information]
  • Sabaretnam, T., Harris, M., Kockx, M., Witting, P., Le Couteur, D., Kritharides, L. (2009). Effects of hydrogen peroxide and apolipoprotein e isoforms on apolipoprotein e trafficking in HepG2 cells. Clinical and Experimental Pharmacology and Physiology, 36(12), e96-e102. [More Information]
  • Goyette, J., Yan, W., Yamen, E., Chung, Y., Lim, S., Hsu, K., Rahimi, F., Di Girolamo, N., Song, C., Jessup, W., Freedman, B., et al (2009). Pleiotropic roles of S100A12 in coronary atherosclerotic plaque formation and rupture. Journal of Immunology, 183(1), 593-603. [More Information]
  • Kim, W., Elliott, D., Kockx, M., Kritharides, L., Rye, K., Jans, D., Garner, B. (2008). Analysis of apolipoprotein E nuclear localization using green fluorescent protein and biotinylation approaches. Biochemical Journal, 409(3), 701-709. [More Information]
  • Kockx, M., Jessup, W., Kritharides, L. (2008). Regulation of endogenous apolipoprotein E secretion by macrophages. Arteriosclerosis, Thrombosis, and Vascular Biology, 28(6), 1060-1067. [More Information]
  • Kockx, M., Guo, D., Huby, T., Lesnik, P., Kay, J., Sabaretnam, T., Jary, E., Hill, M., Gaus, K., Kritharides, L., et al (2007). Secretion of Apolipoprotein E From Macrophages Occurs via a Protein Kinase A and Calcium-Dependent Pathway Along the Microtubule Network. Circulation Research, 101(6), 607-616. [More Information]
  • Gelissen, I., Harris, M., Quinn, C., Rye, K., Brown, A., Kockx, M., Cartland, S., Packianathan, M., Kritharides, L., Jessup, W. (2006). ABCA1 and ABCG1 synergize to mediate cholesterol export to apoA-I. Arteriosclerosis, Thrombosis, and Vascular Biology, 26(3), 534-540. [More Information]
  • Kockx, M., Rye, K., Gaus, K., Quinn, C., Wright, J., Sloane, T., Sviridov, D., Sullivan, D., Fu, Y., Burnett, J., Kritharides, L., et al (2004). Apolipoprotein A-I-Stimulated Apolipoprotein E Secretion From Human Macrophages Is Independent Of Cholesterol Efflux. Journal of Biological Chemistry, 279(25), 25966-25977.
  • Liu, S., Cogny, A., Kockx, M., Dean, R., Gaus, K., Jessup, W., Kritharides, L. (2003). Cyclodextrins differentially mobilize free and esterified cholesterol from primary human foam cell macrophages. Journal of Lipid Research, 44(6), 1156-1166.

2013

  • Kockx, M., Jessup, W., Kritharides, L. (2013). Getting to the 'guts' of the matter: intestinal control of lipid metabolism. Current Opinion in Lipidology, 24(1), 105-106. [More Information]
  • Karunakaran, D., Kockx, M., Owen, D., Burnett, J., Jessup, W., Kritharides, L. (2013). Protein Kinase C Controls Vesicular Transport and Secretion of Apolipoprotein E from Primary Human Macrophages. The Journal of Biological Chemistry, 288(7), 5186-5197. [More Information]

2012

  • Kockx, M., Dinnes, D., Huang, K., Sharpe, L., Jessup, W., Brown, A., Kritharides, L. (2012). Cholesterol accumulation inhibits ER to Golgi transport and protein secretion: studies of apolipoprotein E and VSVGt. The Biochemical Journal, 447(1), 51-60. [More Information]
  • Kockx, M., Kritharides, L. (2012). Cyclosporin A-Induced Hyperlipidemia. In Sasa Frank and Gerhard Kostner (Eds.), Lipoproteins- Role in Health and Diseases, (pp. 337-354). Croatia: InTech Publishers.
  • Gelissen, I., Sharpe, L., Sandoval, C., Rao, G., Kockx, M., Kritharides, L., Jessup, W., Brown, A. (2012). Protein kinase A modulates the activity of a major human isoform of ABCG1. Journal of Lipid Research, 53(10), 2133-2140. [More Information]

2010

  • Kockx, M., Jessup, W., Kritharides, L. (2010). Cyclosporin A and atherosclerosis - Cellular pathways in atherogenesis. Pharmacology and Therapeutics, 128(1), 106-118. [More Information]
  • Lee, Y., Kockx, M., Raftery, M., Jessup, W., Griffith, R., Kritharides, L. (2010). Glycosylation and Sialylation of Macrophage-derived Human Apolipoprotein E Analyzed by SDS-PAGE and Mass Spectrometry: Evidence for a Novel Site of Glycosylation on SER290. Molecular and Cellular Proteomics, 9(9), 1968-1981. [More Information]

2009

  • Kockx, M., Guo, D., Traini, M., Gaus, K., Kay, J., Wimmer-Kleikamp, S., Rentero, C., Burnett, J., Le Goff, W., van Eck, M., Kritharides, L., et al (2009). Cyclosporin A decreases apolipoprotein E secretion from human macrophages via a protein phosphatase2B-dependent and ATP-binding cassette transporter A1 (ABCA1)-independent pathway. Journal of Biological Chemistry, 284(36), 24144-24154. [More Information]
  • Sabaretnam, T., Harris, M., Kockx, M., Witting, P., Le Couteur, D., Kritharides, L. (2009). Effects of hydrogen peroxide and apolipoprotein e isoforms on apolipoprotein e trafficking in HepG2 cells. Clinical and Experimental Pharmacology and Physiology, 36(12), e96-e102. [More Information]
  • Goyette, J., Yan, W., Yamen, E., Chung, Y., Lim, S., Hsu, K., Rahimi, F., Di Girolamo, N., Song, C., Jessup, W., Freedman, B., et al (2009). Pleiotropic roles of S100A12 in coronary atherosclerotic plaque formation and rupture. Journal of Immunology, 183(1), 593-603. [More Information]

2008

  • Kim, W., Elliott, D., Kockx, M., Kritharides, L., Rye, K., Jans, D., Garner, B. (2008). Analysis of apolipoprotein E nuclear localization using green fluorescent protein and biotinylation approaches. Biochemical Journal, 409(3), 701-709. [More Information]
  • Kockx, M., Jessup, W., Kritharides, L. (2008). Regulation of endogenous apolipoprotein E secretion by macrophages. Arteriosclerosis, Thrombosis, and Vascular Biology, 28(6), 1060-1067. [More Information]

2007

  • Kockx, M., Guo, D., Huby, T., Lesnik, P., Kay, J., Sabaretnam, T., Jary, E., Hill, M., Gaus, K., Kritharides, L., et al (2007). Secretion of Apolipoprotein E From Macrophages Occurs via a Protein Kinase A and Calcium-Dependent Pathway Along the Microtubule Network. Circulation Research, 101(6), 607-616. [More Information]

2006

  • Gelissen, I., Harris, M., Quinn, C., Rye, K., Brown, A., Kockx, M., Cartland, S., Packianathan, M., Kritharides, L., Jessup, W. (2006). ABCA1 and ABCG1 synergize to mediate cholesterol export to apoA-I. Arteriosclerosis, Thrombosis, and Vascular Biology, 26(3), 534-540. [More Information]

2004

  • Kockx, M., Rye, K., Gaus, K., Quinn, C., Wright, J., Sloane, T., Sviridov, D., Sullivan, D., Fu, Y., Burnett, J., Kritharides, L., et al (2004). Apolipoprotein A-I-Stimulated Apolipoprotein E Secretion From Human Macrophages Is Independent Of Cholesterol Efflux. Journal of Biological Chemistry, 279(25), 25966-25977.

2003

  • Liu, S., Cogny, A., Kockx, M., Dean, R., Gaus, K., Jessup, W., Kritharides, L. (2003). Cyclodextrins differentially mobilize free and esterified cholesterol from primary human foam cell macrophages. Journal of Lipid Research, 44(6), 1156-1166.

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