Dr Manisha Sharma

Postdoctoral Fellow
Medicine, Westmead Clinical School


Map

Selected grants

2013

  • Characterising the beta-catenin nuclear targeting pathway in cancer; Henderson B, Molloy M, Forwood J, Sharma M; National Health and Medical Research Council (NHMRC)/Project Grants.

2012

  • Novel regulation of beta-catenin intracellular transport and its role in cell polarity and migration; Sharma M, Henderson B; Cancer Council New South Wales/Research Project Grants.

Selected publications

Download citations: PDF RTF Endnote

Book Chapters

  • Sharma, M., Johnson, M., Brocardo, M., Jamieson, C., Henderson, B. (2014). Wnt Signaling Proteins Associate with the Nuclear Pore Complex: Implications for Cancer. In Eric C. Schirmer, and Jose I. de las Heras (Eds.), Cancer Biology and the Nuclear Envelope, (pp. 353-372). New York: Springer.
  • Sharma, M., Henderson, B. (2010). Methods to Measure Nuclear Export of Beta-Catenin Using Fixed and Live Cell Assays. In Paul J. Higgins (Eds.), Transcription Factors: Methods and Protocols - Methods in Molecular Biology Volume 647, (pp. 187-197). United States: Humana Press.

Journals

  • Johnson, M., Sharma, M., Mok, M., Henderson, B. (2013). Stimulation of in vivo nuclear transport dynamics of actin and its co-factors IQGAP1 and Rac1 in response to DNA replication stress. Biochimica et Biophysica Acta (Molecular and Cell Biology of Lipids), 1833 (10), 2334-2347. [More Information]
  • Lui, C., Mills, K., Brocardo, M., Sharma, M., Henderson, B. (2012). APC as a Mobile Scaffold: Regulation and Function at the Nucleus, Centrosomes, and Mitochondria. IUBMB Life, 64(3), 209-214. [More Information]
  • Sharma, M., Jamieson, C., Johnson, M., Molloy, M., Henderson, B. (2012). Specific Armadillo Repeat Sequences Facilitate beta-Catenin Nuclear Transport in Live Cells via Direct Binding to Nucleoporins Nup62, Nup153, and RanBP2/Nup358. Journal of Biological Chemistry, 287(2), 819-831. [More Information]
  • Jamieson, C., Sharma, M., Henderson, B. (2012). Wnt signaling from membrane to nucleus: β-catenin caught in a loop. The International Journal of Biochemistry and Cell Biology, 44(6), 847-850. [More Information]
  • Johnson, M., Sharma, M., Brocardo, M., Henderson, B. (2011). IQGAP1 Translocates to the Nucleus in Early S-Phase and Contributes to Cell Cycle Progression After DNA Replication Arrest. The International Journal of Biochemistry and Cell Biology, 43(1), 65-73. [More Information]
  • Jamieson, C., Sharma, M., Henderson, B. (2011). Regulation of β-Catenin Nuclear Dynamics by GSK-3β Involves a LEF-1 Positive Feedback Loop. Traffic (Malden), 12(8), 983-999. [More Information]
  • Flegg, C., Sharma, M., Medina-Palazon, C., Jamieson, C., Galea, M., Brocardo, M., Mills, K., Henderson, B. (2010). Nuclear Export and Centrosome Targeting of the Protein Phosphatase 2A Subunit B56alpha: Role of B56alpha in Nuclear Export of the Catalytic Subunit. Journal of Biological Chemistry, 285(24), 18144-18154. [More Information]
  • Johnson, M., Sharma, M., Henderson, B. (2009). IQGAP1 regulation and roles in cancer. Cellular Signalling. [More Information]
  • Johnson, M., Sharma, M., Jamieson, C., Henderson, J., Mok, M., Bendall, L., Henderson, B. (2009). Regulation of beta-catenin trafficking to the membrane in living cells. Cellular Signalling, 21(2), 339-348. [More Information]
  • Sharma, M., Henderson, B. (2007). IQ-domain GTPase-activating protein 1 regulates beta-catenin at membrane ruffles and its role in macropinocytosis of N-cadherin and adenomatous polyposis coli. Journal of Biological Chemistry, 282(11), 8545-8556. [More Information]
  • Sharma, M., Leung, L., Brocardo, M., Henderson, J., Flegg, C., Henderson, B. (2006). Membrane localization of adenomatous polyposis coli protein at cellular protrusions: targeting sequences and regulation by beta-catenin. Journal of Biological Chemistry, 281(25), 17140-17149. [More Information]

2014

  • Sharma, M., Johnson, M., Brocardo, M., Jamieson, C., Henderson, B. (2014). Wnt Signaling Proteins Associate with the Nuclear Pore Complex: Implications for Cancer. In Eric C. Schirmer, and Jose I. de las Heras (Eds.), Cancer Biology and the Nuclear Envelope, (pp. 353-372). New York: Springer.

2013

  • Johnson, M., Sharma, M., Mok, M., Henderson, B. (2013). Stimulation of in vivo nuclear transport dynamics of actin and its co-factors IQGAP1 and Rac1 in response to DNA replication stress. Biochimica et Biophysica Acta (Molecular and Cell Biology of Lipids), 1833 (10), 2334-2347. [More Information]

2012

  • Lui, C., Mills, K., Brocardo, M., Sharma, M., Henderson, B. (2012). APC as a Mobile Scaffold: Regulation and Function at the Nucleus, Centrosomes, and Mitochondria. IUBMB Life, 64(3), 209-214. [More Information]
  • Sharma, M., Jamieson, C., Johnson, M., Molloy, M., Henderson, B. (2012). Specific Armadillo Repeat Sequences Facilitate beta-Catenin Nuclear Transport in Live Cells via Direct Binding to Nucleoporins Nup62, Nup153, and RanBP2/Nup358. Journal of Biological Chemistry, 287(2), 819-831. [More Information]
  • Jamieson, C., Sharma, M., Henderson, B. (2012). Wnt signaling from membrane to nucleus: β-catenin caught in a loop. The International Journal of Biochemistry and Cell Biology, 44(6), 847-850. [More Information]

2011

  • Johnson, M., Sharma, M., Brocardo, M., Henderson, B. (2011). IQGAP1 Translocates to the Nucleus in Early S-Phase and Contributes to Cell Cycle Progression After DNA Replication Arrest. The International Journal of Biochemistry and Cell Biology, 43(1), 65-73. [More Information]
  • Jamieson, C., Sharma, M., Henderson, B. (2011). Regulation of β-Catenin Nuclear Dynamics by GSK-3β Involves a LEF-1 Positive Feedback Loop. Traffic (Malden), 12(8), 983-999. [More Information]

2010

  • Sharma, M., Henderson, B. (2010). Methods to Measure Nuclear Export of Beta-Catenin Using Fixed and Live Cell Assays. In Paul J. Higgins (Eds.), Transcription Factors: Methods and Protocols - Methods in Molecular Biology Volume 647, (pp. 187-197). United States: Humana Press.
  • Flegg, C., Sharma, M., Medina-Palazon, C., Jamieson, C., Galea, M., Brocardo, M., Mills, K., Henderson, B. (2010). Nuclear Export and Centrosome Targeting of the Protein Phosphatase 2A Subunit B56alpha: Role of B56alpha in Nuclear Export of the Catalytic Subunit. Journal of Biological Chemistry, 285(24), 18144-18154. [More Information]

2009

  • Johnson, M., Sharma, M., Henderson, B. (2009). IQGAP1 regulation and roles in cancer. Cellular Signalling. [More Information]
  • Johnson, M., Sharma, M., Jamieson, C., Henderson, J., Mok, M., Bendall, L., Henderson, B. (2009). Regulation of beta-catenin trafficking to the membrane in living cells. Cellular Signalling, 21(2), 339-348. [More Information]

2007

  • Sharma, M., Henderson, B. (2007). IQ-domain GTPase-activating protein 1 regulates beta-catenin at membrane ruffles and its role in macropinocytosis of N-cadherin and adenomatous polyposis coli. Journal of Biological Chemistry, 282(11), 8545-8556. [More Information]

2006

  • Sharma, M., Leung, L., Brocardo, M., Henderson, J., Flegg, C., Henderson, B. (2006). Membrane localization of adenomatous polyposis coli protein at cellular protrusions: targeting sequences and regulation by beta-catenin. Journal of Biological Chemistry, 281(25), 17140-17149. [More Information]

To update your profile click here. For support on your academic profile contact .