Associate Professor Marina Kennerson
Principal Research Fellow & Associate Professor
Medicine, Concord Clinical School
ANZAC Research Institute
Telephone | +61 2 9767 9119 |
Fax | +61 2 9767 9101 |
|
Research interests
My research interests are to identifying genes for inherited peripheral neuropathies. These disorders affect the motor and sensory component of the peripheral nervous system and our research is driven to identify the gene mutations that cause the premature death of neurons (neurodegenration) in these disorders.
My research relies on the ascertainment of families for genetic linkage studies and using resources of the Human Genome Project to map chromosomal regions in the families and to find the gene mutation. Our laboratory stays abreast of the latest genome technologies and uses state-of-the-art mutation scanning methods and next generation sequencing strategies. The laboratory has expertise in genetic linkage analysis, molecular biology, next generation sequencing, bioinformatics and gene mapping strategies.
Current research students
Project title | Research student |
---|---|
Correcting GJB1 gene dysregulation in X-linked Charcot-Marie-Tooth neuropathy | Bianca GROSZ |
International links
(University of Malaya)
Collaboration with Dr Azlina Ahmad-Annuar (Department of Biomedical Science, Faculty of Medicine) and Dr Nortina Shahrizaila (Department of Medicine, Faculty of Medcinie) to map genes for inherited peripheral neuropathies in Malaysian families. |
Selected grants
2014
- EVOS FL Auto cell imaging system; Nicholson G, Clark G, Zhou H, Jessup W, Le Couteur D, McMahon A, McLachlan A, Allan C, Handelsman D, Hart D, Walters K, Kritharides L, Kockx M, Kennerson M, Cooper M, Seibel M, Verma N, Silveira P, Fromm P, Simanainen U, Cogger V, Zheng Y; National Health and Medical Research Council (NHMRC)/Equipment Grants.
2013
- IVIS Lumina II in vivo Imaging System; Seibel M, Handelsman D, Le Couteur D, Hart D, Nicholson G, Freedman B, Kritharides L, Jessup W, Zhou H, Clark G, Kennerson M, Allan C, Walters K, Cogger V, McMahon A, Simanainen U, Kockx M, Speranza T, Zheng Y; DVC Research/Equipment Grant.
- Automacs Pro Seperator; Hart D, Handelsman D, Le Couteur D, Nicholson G, Kritharides L, Zhou H, Clark G, Kennerson M, Allan C, Walters K, Cogger V, Simanainen U, Zheng Y, Seibel M; DVC Research/Equipment Grant.
- Gene Identification for Inherited Peripheral Neuropathies by applying Next Generation Sequencing; Kennerson M, Nicholson G; National Health and Medical Research Council (NHMRC)/Project Grants.
2011
- Discovering Genes for X-linked Charcot-Marie-Tooth Neuropathy; Nicholson G, Kennerson M; National Health and Medical Research Council (NHMRC)/Project Grants.
- MOLECULAR IMAGER CHEMIDoc XRS SYSTEM & MINI P ROTEAN GEL/TRANSBLOT Cell SYSTEM (BIO-RAD. AUSTRALIA; Allan C, Handelsman D, Zhou H, Seibel M, Kennerson M, Nicholson G, Blair I, Le Couteur D, McMahon A, Hart D, Clark G, Simanainen U; National Health and Medical Research Council (NHMRC)/Equipment Grants.
2010
- The Lunar PIXImus II DEXA Scanner; Zhou H, Seibel M, Handelsman D, Le Couteur D, Nicholson G, Clarke S, Robertson G, van Zandwijk N, Freedman B, Kennerson M, Allan C, Walters K, Cogger V, Blair I, Reid G, Simanainen U; National Health and Medical Research Council (NHMRC)/Equipment Grants.
2009
- Stereomicroscope-Imaging Workstation; Allan C, Seibel M, Handelsman D, Le Couteur D, Kennerson M, Robertson G, Walters K, Cogger V, Nicholson G, Zhou H, Blair I, Simanainen U, McMahon A; National Health and Medical Research Council (NHMRC)/Equipment Grants.
2008
- Mutation analysis of nevel candidate genes for X-linked Charcot Marine tooth (CMTX3) neuropathy; Kennerson M, Nicholson G; National Health and Medical Research Council (NHMRC)/Project Grants.
- Sirtuins and the molecular epidemiology of frailty in older men; De Cabo R, Cumming R, Le Couteur D, Kennerson M, De Cabo R, Naganathan V, Sambrook P; National Health and Medical Research Council (NHMRC)/Project Grants.
2007
- Finding the gene mutations causing X-linked Charcot-Marie-Tooth neuropathy; Kennerson M; University of Sydney/Bridging Support.
- Finding the gene causing X-linked Charcot-Marie-Tooth (CMTX3) neuropathy; Kennerson M, Nicholson G; Muscular Dystrophy Association of New South Wales/Research Support.
- Leica CM3050 S cryostat; Seibel M, Blair J, Dunstan C, Handelsman D, Nicholson G, Kennerson M, Lowe H, Witting P, Allan C, Zhou H; University of Sydney/Major Equipment Grant.
2006
- Cell culture quarantine and storage facility plus assessories; Dunstan C, Witting P, Myers S, Handelsman D, Seibel M, Nicholson G, Zhou H, Kennerson M, Allan C, Freedman B, Le Couteur D, Muller M; National Health and Medical Research Council (NHMRC)/Equipment Grants.
- KODAK Image Station 2000mm Multi-Modal Imager; Seibel M, Nicholson G, Witting P, Le Couteur D, Freedman B, Dunstan C, Blair J, Kennerson M, Myers S, Muller M; University of Sydney/Major Equipment Grant.
2005
- Victor 3 Multi-label Plate Reader; Witting P, Handelsman D, Le Couteur D, Nicholson G, Seibel M, Kril J, Kritharides L, Kennerson M; University of Sydney/Major Equipment Grant.
- Bio-Rad iCycler iQ5 Real-Time PCR & Mutation detection system; Seibel M, Le Couteur D, Freedman B, Nicholson G, Handelsman D, Kennerson M, Dunstan C, Allan C, Witting P, Kril J, Muller M; National Health and Medical Research Council (NHMRC)/Equipment Grants.
2004
- OPTIMAX TLX 120 ultracentrifuge; Witting P, Handelsman D, Nicholson G, Lay P, Kritharides L, Kril J, Le Couteur D, Lowe H, Kennerson M; National Health and Medical Research Council (NHMRC)/Equipment Grants.
2003
- Molecular genetics of hereditary motor and sensory neuropathy with pyramidal signs; Nicholson G, Kennerson M; National Health and Medical Research Council (NHMRC)/Project Grants.
2001
- Finding the gene for hereditary sensory neuropathy: a new cause of sensory neurone degeneration; Nicholson G, Kennerson M; Rebecca L Cooper/Medical Research Foundation.
- Genetic bases for Charcot-Marie-Tooth and Hereditary Sensory type 1 Neuropathies; Nicholson G, Kennerson M; National Health and Medical Research Council (NHMRC)/Project Grants.
2000
- Gene mutation analysis in parkinsons disease using real-time PCR; Nicholson G, Kennerson M; Clive & Vera Ramaciotti Foundation/Research Grants.
Selected publications
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|