Associate Professor Michael Valenzuela

Associate Professor
Brain & Mind Research Institute, Sydney Medical School

Telephone 02 9114 4135

Map

Selected grants

2015

  • Modifying the Trajectory of Insidious Late Life Cognitive Decline using Computerised Cognitive Training; Valenzuela M, Naismith S; National Health and Medical Research Council (NHMRC)/Project Grants.

2012

  • Regenerative Neuroscience Strategies for Brain Ageing and Dementia; Valenzuela M; National Health and Medical Research Council (NHMRC)/Career Development Fellowship.
  • Neurogenesis in Depression using Magnetic Resonance Spectroscopy; Valenzuela M, Yucel M, Velakoulis D, Dragunow M, Loo C, Pujol J; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Which Mental Activities and When for Dementia Prevention The Four Nations Longitudinal Collaboration; Valenzuela M, Ritchie K, Brayne C, Stern Y; National Health and Medical Research Council (NHMRC)/Project Grants.

2011

  • The Healthy Brain Project: A prospective cohort study to examine how later-life university education may affect the trajectory of ageing-related cognitive decline; Valenzuela M; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Role of Neurogenesis in Clinical Recovery from Depression during ECT: Application of a Novel in vivo Magnetic Resonance Spectoscopy Technology; Valenzuela M; National Health and Medical Research Council (NHMRC)/Career Development Awards.

2010

  • Boosting the Mental Wealth and Cognitive Capacity of Working Australians; Valenzuela M; The Brain Department Pty Ltd./Research Support.
  • Detection and induction of in vivo neurogenesis in humans using a novel magnetic resonance spectroscopy technique; Valenzuela M; Pfizer/Research Grant.
  • Skin derived neural stem cells for Alzheimer's Disease - in vivo studies; Valenzuela M; Rebecca L Cooper Medical Research Foundation/Research Grant.

2009

  • Post Doctural Fellow grant; Valenzuela M; UNSW/Faculty of Medicine Post Doctoral Fellow Grant.
  • Microstructure of Brain Reserve; Valenzuela M; UNSW/Goldstar Research Grant.

2008

  • Skin derived neural stem cells for reversal of age-associated cognitive impairment; Valenzuela M; Mason Foundation/Mason Foundation Research Grants Program.
  • THE SMART Trial - Study of Mental Activity and Regular Training; Valenzuela M; National Health and Medical Research Council (NHMRC)/Dementia Research Team Grants.

Selected publications

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Books

  • Valenzuela, M. (2011). Maintain Your Brain: What you can do to improve your brains health and avoid dementia. Sydney, Australia: ABC Books.
  • Valenzuela, M. (2009). Its Never Too Late to Change Your Mind: The Latest Medical Thinking on What You Can Do to Avoid Dementia. Sydney: ABC Books.

Book Chapters

  • Suo, C., Valenzuela, M. (2012). Neuroimaging Outcomes of Brain Training Trials. In Prof. Peter Bright (Eds.), Neuroimaging - Cognitive and Clinical Neuroscience, (pp. 417-430). Rijeka, Croatia: Intech.
  • Valenzuela, M. (2011). The Changing Brain. HEALTH, (pp. 174-185). Future Leaders.

Journals

  • Carrasco, J., Georgevsky, D., Valenzuela, M., McGreevy, P. (2014). A pilot study of sexual dimorphism in the head morphology of domestic dogs. Journal of Veterinary Behavior: clinical applications and research, 9(1), 43-46. [More Information]
  • Georgevsky, D., Carrasco, J., Valenzuela, M., McGreevy, P. (2014). Domestic dog skull diversity across breeds , breed groupings and genetic clusters. Journal of Veterinary Behavior: clinical applications and research, 9(5), 228-234.
  • Hong, A., Suo, C., Valenzuela, M., Haydu, L., Jacobsen, K., Reisse, C., Fogarty, G. (2014). Low incidence of melanoma brain metastasis in the hippocampus. Radiotherapy and Oncology, 111, 59-62. [More Information]
  • Gates, N., Valenzuela, M., Sachdev, P., Fiatarone Singh, M. (2014). Psychological well-being in individuals with mild cognitive impairment. Clinical Interventions in Aging, 9, 779-792. [More Information]
  • Fiatarone Singh, M., Gates, N., Jain, N., Wilson, G., Meiklejohn, J., Brodaty, H., Wen, W., Singh, N., Baune, B., Suo, C., Baker, M., Foroughi, N., Valenzuela, M., et al (2014). The SMART study - Resistance training and/or cognitive training in mild cognitive impairment: A randomized, double-blind, double-sham controlled trial. Journal of the American Medical Directors Association, In Press.
  • Fiatarone Singh, M., Gates, N., Jain, N., Wilson, G., Meiklejohn, J., Brodaty, H., Wen, W., Singh, N., Baune, B., Suo, C., Baker, M., Foroughi, N., Valenzuela, M., et al (2014). The study of mental and resistance training (SMART) study - resistance training and/or cognitive training in mild cognitive impairment: A randomized, double-blind, double-sham controlled trial. Journal of the American Medical Directors Association, In Press.
  • Siette, J., Westbrook, R., Cotman, C., Sidhu, K., Zhu, W., Sachdev, P., Valenzuela, M. (2013). Age-Specific Effects of Voluntary Exercise on Memory and the Older Brain. Biological Psychiatry, 73(5), 435-442. [More Information]
  • Valenzuela, M., Leon, I., Suo, C., Martinez Piamba, D., Kochan, N., Brodaty, H., Sachdev, P. (2013). Cognitive Lifestyle in Older Persons: The Population-Based Sydney Memory & Ageing Study. Journal of Alzheimer's Disease, 36(1), 87-97. [More Information]
  • McGreevy, P., Georgevsky, D., Carrasco, J., Valenzuela, M., Duffy, D., Serpell, J. (2013). Dog Behavior Co-Varies with Height, Bodyweight and Skull Shape. PLoS One, 8(12), 1-7. [More Information]
  • Valenzuela, M., Bartres-Faz, D., Bullmore, E., Fjell, A., Maletic-Savetic, M., Martins, R., Solowij, N., Yucel, M. (2013). More thinking about less data: a perspective from the 2nd Provence Summer Workshop. Molecular Psychiatry, 18(5), 524-525. [More Information]
  • Borness, C., Proudfoot, J., Crawford, J., Valenzuela, M. (2013). Putting Brain Training to the Test in the Workplace: A Randomized, Blinded, Multisite, Active-Controlled Trial. PLoS One, 8(3), 1-8. [More Information]
  • Gates, N., Fiatarone Singh, M., Sachdev, P., Valenzuela, M. (2013). The Effect of Exercise Training on Cognitive Function in Older Adults with Mild Cognitive Impairment: A Meta-analysis of Randomized Controlled Trials. American Journal of Geriatric Psychiatry, 21(11), 1086-1097. [More Information]
  • Summers, M., Saunders, N., Valenzuela, M., Summers, J., Ritchie, K., Robinson, A., Vickers, J. (2013). The Tasmanian Healthy Brain Project (THBP): a prospective longitudinal examination of the effect of university-level education in older adults in preventing age-related cognitive decline and reducing the risk of dementia. International Psychogeriatrics, 25(7), 1145-1155. [More Information]
  • Marioni, R., van den Hout, A., Valenzuela, M., Brayne, C., Matthews, F. (2012). Active cognitive lifestyle associates with cognitive recovery and a reduced risk of cognitive decline. Journal of Alzheimer's Disease, 28(1), 223-230. [More Information]
  • Marioni, R., Valenzuela, M., van den Hout, A., Brayne, C., Matthews, F. (2012). Active cognitive lifestyle is associated with positive cognitive health transitions and compression of morbidity from age sixty-five. PLoS One, 7(12), 1-6. [More Information]
  • Valenzuela, M., Esler, M., Ritchie, K., Brodaty, H. (2012). Antihypertensives for combating dementia? A perspective on candidate molecular mechanisms and population-based prevention. Translational Psychiatry, 2, 1-10. [More Information]
  • Salvin, H., MaGrath, C., McGreevy, P., Valenzuela, M. (2012). Development of a novel paradigm for the measurement of olfactory discrimination in dogs (Canis familiaris): A pilot study. Journal of Veterinary Behavior: clinical applications and research, 7(1), 3-10. [More Information]
  • Borness, C., Proudfoot, J., Valenzuela, M. (2012). Methodological Challenges and Solutions When Conducting a Multicenter, Online, Randomized Controlled Trial of Brain Training Within a Public Service Organization. Journal of Workplace Behavioral Health: employee assistance practice and research, 27(4), 272-288. [More Information]
  • Valenzuela, M., Matthews, F., Brayne, C., Ince, P., Halliday, G., Kril, J., Dalton, M., Richardson, K., Forster, G., Sachdev, P. (2012). Multiple Biological Pathways Link Cognitive Lifestyle to Protection from Dementia. Biological Psychiatry, 71(9), 783-791. [More Information]
  • Suo, C., Leon, I., Brodaty, H., Troller, J., Wen, W., Sachdev, P., Valenzuela, M. (2012). Supervisory experience at work is linked to low rate of hippocampal atrophy in late life. NeuroImage, 63(3), 1542-1551. [More Information]
  • Gates, N., Sachdev, P., Fiatarone Singh, M., Valenzuela, M. (2011). Cognitive and memory training in adults at risk of dementia: A Systematic Review. BMC Geriatrics, 11(Article 55), 1-14. [More Information]
  • Valenzuela, M., Sachdev, P., Wen, W., Chen, X., Brodaty, H. (2008). Lifespan Mental Activity Predicts Diminished Rate of Hippocampal Atrophy. PLoS One, 3(7), 1-6. [More Information]

Conferences

  • Valenzuela, M. (2011). Cultivating a Cognitive Lifestyle. National Dementia Research Forum 2011, Sydney.
  • Valenzuela, M. (2011). Dogs, dermis and dementia: Regeneration and degeneration in man's best friend. Alzheimer's Australia 14th National Conference, Brisbane.
  • Valenzuela, M. (2011). Early Career Research Session - Grantsmanship. National Dementia Research Forum 2011, Sydney.
  • Valenzuela, M. (2011). Exercise for the mind and the body. National Dementia Research Forum 2011, Sydney.
  • Valenzuela, M. (2011). Neurogenesis in the Live Human Brain: Opportunities and Challenges for Psychiatry. First National Symposium On Translational Psychiatry.
  • Valenzuela, M. (2010). Cognitive Lifestyle and Brain Training. International Federation of Aging 2010, Melbourne.
  • Valenzuela, M. (2010). Detection of neurogenesis in psychiatric patients for response prediction. Neuroimaging as Endpoints in Clinical Trials Summer Workshop, Provence, France.
  • Valenzuela, M. (2009). Brain Training for the Prevention of dementia. Masterclass in Alzheimer's Disease, Sydney.
  • Valenzuela, M. (2009). Cognitive Lifestyle, Dogs, Dermis and Dementia Prevention. Columbia University College of Surgeons and Physicians seminar series.
  • Valenzuela, M. (2009). Reducing Dementia Risk: Cognitive lifestyle and brain training. International Federation of Aging 10th Global Conference of Aging, Melbourne.
  • Valenzuela, M. (2008). Can Cognitive Training Prevent Dementia. Alzheimer's Association International Conference on Alzheimer's Disease AAICAD 2009, United States: Alzheimers Association.
  • Valenzuela, M. (2008). Lifespan Mental Activity Predicts Diminished Rate of Hippocampal Atrophy. Alzheimer's Association International Conference on Alzheimer's Disease AAICAD 2008, United States: Alzheimers Association.
  • Valenzuela, M. (2008). The SMART Trial: Study of Mental Activity & Regular Training for the prevention of cognitive decline in at-risk elderly. International College of Geriatric Psychoneuropharmacology, Sydney.
  • Valenzuela, M. (2008). Use it or Lose it - Preventing Cognitive Decline. Annual Scientific Meeting of the Australian and New Zealand College of Anaesthetists (ANZCA), Sydney: Australian and New Zealand College of Anaesthetists.

2014

  • Carrasco, J., Georgevsky, D., Valenzuela, M., McGreevy, P. (2014). A pilot study of sexual dimorphism in the head morphology of domestic dogs. Journal of Veterinary Behavior: clinical applications and research, 9(1), 43-46. [More Information]
  • Georgevsky, D., Carrasco, J., Valenzuela, M., McGreevy, P. (2014). Domestic dog skull diversity across breeds , breed groupings and genetic clusters. Journal of Veterinary Behavior: clinical applications and research, 9(5), 228-234.
  • Hong, A., Suo, C., Valenzuela, M., Haydu, L., Jacobsen, K., Reisse, C., Fogarty, G. (2014). Low incidence of melanoma brain metastasis in the hippocampus. Radiotherapy and Oncology, 111, 59-62. [More Information]
  • Gates, N., Valenzuela, M., Sachdev, P., Fiatarone Singh, M. (2014). Psychological well-being in individuals with mild cognitive impairment. Clinical Interventions in Aging, 9, 779-792. [More Information]
  • Fiatarone Singh, M., Gates, N., Jain, N., Wilson, G., Meiklejohn, J., Brodaty, H., Wen, W., Singh, N., Baune, B., Suo, C., Baker, M., Foroughi, N., Valenzuela, M., et al (2014). The SMART study - Resistance training and/or cognitive training in mild cognitive impairment: A randomized, double-blind, double-sham controlled trial. Journal of the American Medical Directors Association, In Press.
  • Fiatarone Singh, M., Gates, N., Jain, N., Wilson, G., Meiklejohn, J., Brodaty, H., Wen, W., Singh, N., Baune, B., Suo, C., Baker, M., Foroughi, N., Valenzuela, M., et al (2014). The study of mental and resistance training (SMART) study - resistance training and/or cognitive training in mild cognitive impairment: A randomized, double-blind, double-sham controlled trial. Journal of the American Medical Directors Association, In Press.

2013

  • Siette, J., Westbrook, R., Cotman, C., Sidhu, K., Zhu, W., Sachdev, P., Valenzuela, M. (2013). Age-Specific Effects of Voluntary Exercise on Memory and the Older Brain. Biological Psychiatry, 73(5), 435-442. [More Information]
  • Valenzuela, M., Leon, I., Suo, C., Martinez Piamba, D., Kochan, N., Brodaty, H., Sachdev, P. (2013). Cognitive Lifestyle in Older Persons: The Population-Based Sydney Memory & Ageing Study. Journal of Alzheimer's Disease, 36(1), 87-97. [More Information]
  • McGreevy, P., Georgevsky, D., Carrasco, J., Valenzuela, M., Duffy, D., Serpell, J. (2013). Dog Behavior Co-Varies with Height, Bodyweight and Skull Shape. PLoS One, 8(12), 1-7. [More Information]
  • Valenzuela, M., Bartres-Faz, D., Bullmore, E., Fjell, A., Maletic-Savetic, M., Martins, R., Solowij, N., Yucel, M. (2013). More thinking about less data: a perspective from the 2nd Provence Summer Workshop. Molecular Psychiatry, 18(5), 524-525. [More Information]
  • Borness, C., Proudfoot, J., Crawford, J., Valenzuela, M. (2013). Putting Brain Training to the Test in the Workplace: A Randomized, Blinded, Multisite, Active-Controlled Trial. PLoS One, 8(3), 1-8. [More Information]
  • Gates, N., Fiatarone Singh, M., Sachdev, P., Valenzuela, M. (2013). The Effect of Exercise Training on Cognitive Function in Older Adults with Mild Cognitive Impairment: A Meta-analysis of Randomized Controlled Trials. American Journal of Geriatric Psychiatry, 21(11), 1086-1097. [More Information]
  • Summers, M., Saunders, N., Valenzuela, M., Summers, J., Ritchie, K., Robinson, A., Vickers, J. (2013). The Tasmanian Healthy Brain Project (THBP): a prospective longitudinal examination of the effect of university-level education in older adults in preventing age-related cognitive decline and reducing the risk of dementia. International Psychogeriatrics, 25(7), 1145-1155. [More Information]

2012

  • Marioni, R., van den Hout, A., Valenzuela, M., Brayne, C., Matthews, F. (2012). Active cognitive lifestyle associates with cognitive recovery and a reduced risk of cognitive decline. Journal of Alzheimer's Disease, 28(1), 223-230. [More Information]
  • Marioni, R., Valenzuela, M., van den Hout, A., Brayne, C., Matthews, F. (2012). Active cognitive lifestyle is associated with positive cognitive health transitions and compression of morbidity from age sixty-five. PLoS One, 7(12), 1-6. [More Information]
  • Valenzuela, M., Esler, M., Ritchie, K., Brodaty, H. (2012). Antihypertensives for combating dementia? A perspective on candidate molecular mechanisms and population-based prevention. Translational Psychiatry, 2, 1-10. [More Information]
  • Salvin, H., MaGrath, C., McGreevy, P., Valenzuela, M. (2012). Development of a novel paradigm for the measurement of olfactory discrimination in dogs (Canis familiaris): A pilot study. Journal of Veterinary Behavior: clinical applications and research, 7(1), 3-10. [More Information]
  • Borness, C., Proudfoot, J., Valenzuela, M. (2012). Methodological Challenges and Solutions When Conducting a Multicenter, Online, Randomized Controlled Trial of Brain Training Within a Public Service Organization. Journal of Workplace Behavioral Health: employee assistance practice and research, 27(4), 272-288. [More Information]
  • Valenzuela, M., Matthews, F., Brayne, C., Ince, P., Halliday, G., Kril, J., Dalton, M., Richardson, K., Forster, G., Sachdev, P. (2012). Multiple Biological Pathways Link Cognitive Lifestyle to Protection from Dementia. Biological Psychiatry, 71(9), 783-791. [More Information]
  • Suo, C., Valenzuela, M. (2012). Neuroimaging Outcomes of Brain Training Trials. In Prof. Peter Bright (Eds.), Neuroimaging - Cognitive and Clinical Neuroscience, (pp. 417-430). Rijeka, Croatia: Intech.
  • Suo, C., Leon, I., Brodaty, H., Troller, J., Wen, W., Sachdev, P., Valenzuela, M. (2012). Supervisory experience at work is linked to low rate of hippocampal atrophy in late life. NeuroImage, 63(3), 1542-1551. [More Information]

2011

  • Gates, N., Sachdev, P., Fiatarone Singh, M., Valenzuela, M. (2011). Cognitive and memory training in adults at risk of dementia: A Systematic Review. BMC Geriatrics, 11(Article 55), 1-14. [More Information]
  • Valenzuela, M. (2011). Cultivating a Cognitive Lifestyle. National Dementia Research Forum 2011, Sydney.
  • Valenzuela, M. (2011). Dogs, dermis and dementia: Regeneration and degeneration in man's best friend. Alzheimer's Australia 14th National Conference, Brisbane.
  • Valenzuela, M. (2011). Early Career Research Session - Grantsmanship. National Dementia Research Forum 2011, Sydney.
  • Valenzuela, M. (2011). Exercise for the mind and the body. National Dementia Research Forum 2011, Sydney.
  • Valenzuela, M. (2011). Maintain Your Brain: What you can do to improve your brains health and avoid dementia. Sydney, Australia: ABC Books.
  • Valenzuela, M. (2011). Neurogenesis in the Live Human Brain: Opportunities and Challenges for Psychiatry. First National Symposium On Translational Psychiatry.
  • Valenzuela, M. (2011). The Changing Brain. HEALTH, (pp. 174-185). Future Leaders.

2010

  • Valenzuela, M. (2010). Cognitive Lifestyle and Brain Training. International Federation of Aging 2010, Melbourne.
  • Valenzuela, M. (2010). Detection of neurogenesis in psychiatric patients for response prediction. Neuroimaging as Endpoints in Clinical Trials Summer Workshop, Provence, France.

2009

  • Valenzuela, M. (2009). Brain Training for the Prevention of dementia. Masterclass in Alzheimer's Disease, Sydney.
  • Valenzuela, M. (2009). Cognitive Lifestyle, Dogs, Dermis and Dementia Prevention. Columbia University College of Surgeons and Physicians seminar series.
  • Valenzuela, M. (2009). Its Never Too Late to Change Your Mind: The Latest Medical Thinking on What You Can Do to Avoid Dementia. Sydney: ABC Books.
  • Valenzuela, M. (2009). Reducing Dementia Risk: Cognitive lifestyle and brain training. International Federation of Aging 10th Global Conference of Aging, Melbourne.

2008

  • Valenzuela, M. (2008). Can Cognitive Training Prevent Dementia. Alzheimer's Association International Conference on Alzheimer's Disease AAICAD 2009, United States: Alzheimers Association.
  • Valenzuela, M., Sachdev, P., Wen, W., Chen, X., Brodaty, H. (2008). Lifespan Mental Activity Predicts Diminished Rate of Hippocampal Atrophy. PLoS One, 3(7), 1-6. [More Information]
  • Valenzuela, M. (2008). Lifespan Mental Activity Predicts Diminished Rate of Hippocampal Atrophy. Alzheimer's Association International Conference on Alzheimer's Disease AAICAD 2008, United States: Alzheimers Association.
  • Valenzuela, M. (2008). The SMART Trial: Study of Mental Activity & Regular Training for the prevention of cognitive decline in at-risk elderly. International College of Geriatric Psychoneuropharmacology, Sydney.
  • Valenzuela, M. (2008). Use it or Lose it - Preventing Cognitive Decline. Annual Scientific Meeting of the Australian and New Zealand College of Anaesthetists (ANZCA), Sydney: Australian and New Zealand College of Anaesthetists.

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