Dr Min Kim

Senior Research Fellow
Medicine, Westmead Clinical School
Westmead Millennium Institute for Medical Research

Telephone +61 2 9845 5583
Fax +61 2 9845 9100

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Research interests

We have identified immunodominant CD4 T cell epitopes in HSV-2 glycoprotein D (gD). Those peptides are thought to be effective on a broad range of MHC class II types and cross-reactive between HSV-1 and HSV-2. Recently, immunodominant CD8 T cell epitopes of HSV-2 have been identified in our lab. Our immunodominant peptides for CD4 and CD8 T cells are conjugated to lipid adjuvant to enhance the immunogenicity. The action mechanism of those vaccine candidate peptides are investigated in the interaction of dendritic cells, natural killer cells, and T cells in an attempt to improve the current vaccine candidates.

Selected grants

2015

  • The Role of Dendritic Cells in Sexual Transmission of HIV and Viral Reservoir Formation; Harman A, Cunningham A, Palmer S, Kim M, Nasr N; National Health and Medical Research Council (NHMRC)/Project Grants.

Selected publications

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Book Chapters

  • Cunningham, A., Harman, A., Kim, M., Nasr, N., Lai, J. (2013). Immunobiology of Dendritic Cells and the Influence of HIV Infection. In Li Wu, Olivier Schwartz (Eds.), HIV Interactions with Dendritic Cells: Infection and Immunity, (pp. 1-44). New York, USA: Springer Science + Business Media.
  • Cunningham, A., Harman, A., Kim, M., Nasr, N., Lai, J. (2013). Immunobiology of Dendritic Cells and the Influence of HIV Infection. In Li Wu, Olivier Schwartz (Eds.), HIV Interactions with Dendritic Cells: Infection and Immunity, (pp. 1-44). New York, USA: Springer Science + Business Media.
  • Cunningham, A., Garland, S., Donaghy, H., Kim, M. (2011). Mucosal Immunity in Sexually Transmitted Infections. In Gerd Gross, Stephen K. Tyring (Eds.), Sexually Transmitted Infections and Sexually Transmitted Diseases, (pp. 49-73). Heidelberg, Germany: Springer.

Journals

  • Harman, A., Bye, C., Nasr, N., Sandgren, K., Kim, M., Mercier, S., Botting, R., Lewin, S., Cunningham, A., Cameron, P. (2013). Identification of Lineage Relationships and Novel Markers of Blood and Skin Human Dendritic Cells. Journal of Immunology, 190(1), 66-79. [More Information]
  • Harman, A., Kim, M., Nasr, N., Sandgren, K., Cameron, P. (2013). Tissue dendritic cells as portals for HIV entry. Reviews in Medical Virology, 23(5), 319-333. [More Information]
  • Kim, M., Osbourne, N., Zeng, W., Donaghy, H., McKinnon, K., Jackson, D., Cunningham, A. (2012). Herpes Simplex Virus Antigens Directly Activate NK Cells via TLR2, Thus Facilitating Their Presentation to CD4 T Lymphocytes. Journal of Immunology, 188(9), 4158-4170. [More Information]
  • Lih, A., Nandapalan, H., Kim, M., Yap, C., Lee, P., Ganda, K., Seibel, M. (2010). Targeted intervention reduces refracture rates in patients with incident non-vertebral osteoporotic fractures: a 4-year prospective controlled study. Osteoporosis International, 22(3), 849-858. [More Information]
  • Zaunders, J., Munier, M., Seddiki, N., Pett, S., Ip, S., Bailey, M., Xu, Y., Brown, K., Dyer, W., Kim, M., Cunningham, A., et al (2009). High Levels of Human Antigen-Specific CD4+ T Cells in Peripheral Blood Revealed by Stimulated Coexpression of CD25 and CD134 (OX40). Journal of Immunology, 183(4), 2827-2836. [More Information]
  • Kim, M., Taylor, J., Sidney, J., Mikloska, Z., Bodsworth, N., Lagios, K., Dunckley, H., Byth, K., Denis, M., Finlayson, R., Cunningham, A., et al (2008). Immunodominant Epitopes in Herpes Simplex Virus Type 2 Glycoprotein D Are Recognized by CD4 Lymphocytes from Both HSV-1 and HSV-2 Seropositive Subjects1. Journal of Immunology, 181(9), 6604-6615. [More Information]
  • Cunningham, A., Diefenbach, R., Miranda Saksena, M., Bosnjak, L., Kim, M., Jones, C., Douglas, M. (2006). The cycle of human herpes simplex virus infection: virus transport and immune control. The Journal of Infectious Diseases, 194(Supplement 1), S11-S18. [More Information]

2013

  • Harman, A., Bye, C., Nasr, N., Sandgren, K., Kim, M., Mercier, S., Botting, R., Lewin, S., Cunningham, A., Cameron, P. (2013). Identification of Lineage Relationships and Novel Markers of Blood and Skin Human Dendritic Cells. Journal of Immunology, 190(1), 66-79. [More Information]
  • Cunningham, A., Harman, A., Kim, M., Nasr, N., Lai, J. (2013). Immunobiology of Dendritic Cells and the Influence of HIV Infection. In Li Wu, Olivier Schwartz (Eds.), HIV Interactions with Dendritic Cells: Infection and Immunity, (pp. 1-44). New York, USA: Springer Science + Business Media.
  • Cunningham, A., Harman, A., Kim, M., Nasr, N., Lai, J. (2013). Immunobiology of Dendritic Cells and the Influence of HIV Infection. In Li Wu, Olivier Schwartz (Eds.), HIV Interactions with Dendritic Cells: Infection and Immunity, (pp. 1-44). New York, USA: Springer Science + Business Media.
  • Harman, A., Kim, M., Nasr, N., Sandgren, K., Cameron, P. (2013). Tissue dendritic cells as portals for HIV entry. Reviews in Medical Virology, 23(5), 319-333. [More Information]

2012

  • Kim, M., Osbourne, N., Zeng, W., Donaghy, H., McKinnon, K., Jackson, D., Cunningham, A. (2012). Herpes Simplex Virus Antigens Directly Activate NK Cells via TLR2, Thus Facilitating Their Presentation to CD4 T Lymphocytes. Journal of Immunology, 188(9), 4158-4170. [More Information]

2011

  • Cunningham, A., Garland, S., Donaghy, H., Kim, M. (2011). Mucosal Immunity in Sexually Transmitted Infections. In Gerd Gross, Stephen K. Tyring (Eds.), Sexually Transmitted Infections and Sexually Transmitted Diseases, (pp. 49-73). Heidelberg, Germany: Springer.

2010

  • Lih, A., Nandapalan, H., Kim, M., Yap, C., Lee, P., Ganda, K., Seibel, M. (2010). Targeted intervention reduces refracture rates in patients with incident non-vertebral osteoporotic fractures: a 4-year prospective controlled study. Osteoporosis International, 22(3), 849-858. [More Information]

2009

  • Zaunders, J., Munier, M., Seddiki, N., Pett, S., Ip, S., Bailey, M., Xu, Y., Brown, K., Dyer, W., Kim, M., Cunningham, A., et al (2009). High Levels of Human Antigen-Specific CD4+ T Cells in Peripheral Blood Revealed by Stimulated Coexpression of CD25 and CD134 (OX40). Journal of Immunology, 183(4), 2827-2836. [More Information]

2008

  • Kim, M., Taylor, J., Sidney, J., Mikloska, Z., Bodsworth, N., Lagios, K., Dunckley, H., Byth, K., Denis, M., Finlayson, R., Cunningham, A., et al (2008). Immunodominant Epitopes in Herpes Simplex Virus Type 2 Glycoprotein D Are Recognized by CD4 Lymphocytes from Both HSV-1 and HSV-2 Seropositive Subjects1. Journal of Immunology, 181(9), 6604-6615. [More Information]

2006

  • Cunningham, A., Diefenbach, R., Miranda Saksena, M., Bosnjak, L., Kim, M., Jones, C., Douglas, M. (2006). The cycle of human herpes simplex virus infection: virus transport and immune control. The Journal of Infectious Diseases, 194(Supplement 1), S11-S18. [More Information]

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