Dr Min Kim
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Level A-Research Only
Westmead Millennium Institute |
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Biographical details
1. Cunningham, Anthony L., Kim M. et al., 2010. Manipulation of dendritic cell function by viruses. Curr. Opin. Microbiol. 13, 1-6. [More...]
Research interests
We have identified immunodominant CD4 T cell epitopes in HSV-2 glycoprotein D (gD). Those peptides are thought to be effective on a broad range of MHC class II types and cross-reactive between HSV-1 and HSV-2. Recently, immunodominant CD8 T cell epitopes of HSV-2 have been identified in our lab. Our immunodominant peptides for CD4 and CD8 T cells are conjugated to lipid adjuvant to enhance the immunogenicity. The action mechanism of those vaccine candidate peptides are investigated in the interaction of dendritic cells, natural killer cells, and T cells in an attempt to improve the current vaccine candidates.