Dr Mustafa Khasraw

Oncology Senior Research Fellow and Clinical Lead
NHMRC Clinical Trials Centre, Sydney Medical School and Medical Oncologist at Royal North Shore Hospital in Sydney


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Biographical details

Dr Mustafa Khasraw is a medical oncologist at Royal North Shore Hospital in Sydney. He is also a senior research fellow at the NHMRC Clinical Trials Centre of The University of Sydney, Clinical Lead for the Cooperative Trials Group for Neuro-Oncology (COGNO), cancer research fellow at Deakin University with leading role in several clinical and translational laboratory programs.

Until April 2015 he was the clinical lead of the Haematology and Oncology Clinical Trials at Andrew Love Cancer Centre in Geelong and practised as a Medical Oncologist at Geelong and Royal Melbourne Hospitals.

He completed his medical oncology training at Royal North Shore Hospital in Sydney and he undertook a subsequent oncology fellowship training in the US at Memorial Sloan-Kettering Cancer Centre in New York. His fellowship was both in neuro-oncology and in breast cancer. He is a member of several research committees and the coordinating principal investigator for several multi centre clinical trials. He has been the lead author of numerous manuscripts and book chapters and he acts regularly as a reviewer for a number of scientific journals and grant review committees.

Research interests

Current projects

Dr Khasraw is senior research fellow and clinical lead for The Cooperative Trials Group for Neuro-Oncology (COGNO)and he is also involved in numerous collaborative research projects across the following tumour streams:

  • Clinical Trials
  • Neuro-oncology
  • Breast Cancer
  • Neuroendocrine Tumours

Coordination principal investigator/ study chair of the following studies:

  • ExCentric: Radiotherapy (RT), temozolomide (TMZ), procarbazine (PCB), and the integrin inhibitor cilengitide in patients with glioblastoma (GBM) without methylation of the MGMT gene promoter (CO-PI)
  • NEONAB: Tailored Neoadjuvant Epirubicin And Cyclophosphamide (EC) And Nanoparticle Albumin Bound (nab) Paclitaxel For Newly Diagnosed Breast Cancer
  • NABNEC: NAB-Paclitaxel In Combination With Carboplatin As First Line Treatment Of Gastrointestinal Neuroendocrine Carcinomas
  • The TULIP study: Lithium as a neuroprotective agent in patients undergoing prophylactic cranial irradiation (PCI) for small cell lung cancer (SCLC).
  • The VERTU study: VEliparib, Radiotherapy and Temozolomide trial in Unmethylated MGMT Glioblastoma

Associations

Committee Memberships:

  • Member of the Barwon Health Research Review Committee 2012-2015
  • Member of the Breast Cancer Network Australia's Strategic Advisory Group 2012- ongoing
  • Member of the therapeutic committee of ANZ Breast Cancer Trials Group (ANZBCTG) 2012-ongoing
  • Member of the Scientific Advisory Committee of the Cure Brain Cancer Foundation 2014 - ongoing
  • Medical Co-director of the Rotary Foundation- Geelong District 2012-ongoing

Other activities

  • 2016 Member of the Asian Society of Neurooncology Meeting organising committee
  • 2014 Convener of the COGNO Annual Meeting
  • 2013 Member of the COGNO Annual Meeting organising committee
  • 2012 Member of the COGNO Annual Meeting organising committee
  • 2012 Member of the MOGA Annual Meeting organising committee

Selected grants

2015

  • VERTU – VEliparib, Radiotherapy and Temozolimde trial in newly diagnosed Unmethylated MGMT Glioblastoma; Khasraw M, Simes R; Cure Brain Cancer Foundation/Research Grant.

Selected publications

Download citations: PDF RTF Endnote

Book Chapters

  • Khasraw, M., Noy, A., Gilbert, M., Omuro, A. (2012). Neurological Complications of Non-Hodgkin Lymphoma. In Tracy Batchelor, Lisa M DeAngelis (Eds.), Lymphoma and Leukemia of the Nervous System, (pp. 267-286). New York: Springer Science+Business Media.
  • Khasraw, M., Khakoo, Y. (2012). Paraneoplastic Syndromes Affecting the Nervous System. In Kenneth F. Swaiman, Stephen Ashwal, Donna M Ferriero, Nina F Schor (Eds.), Swaiman's Pediatric Neurology: Principles and Practice, 5th Ed, (pp. 1388-1394). Canada: Elsevier Inc.

Journals

  • Khasraw, M., Ameratunga, M., Grant, R., Wheeler, H., Pavlakis, N. (2014). Antiangiogenic therapy for high-grade glioma. Cochrane Database of Systematic Reviews, 2014 (9), 1-42. [More Information]
  • Khasraw, M., Simeonovic, M., Grommes, C. (2014). Bevacizumab for the treatment of high-grade glioma. Expert Opinion on Biological Therapy, 12(8), 1101-1111. [More Information]
  • Khasraw, M., Ameratunga, M., Grommes, C. (2014). Bevacizumab for the treatment of high-grade glioma: an update after phase III trials. Expert Opinion on Biological Therapy, 14(5), 729-740. [More Information]
  • Hao-Wen, S., Morris, P., Patil, S., Khasraw, M. (2014). Brain metastases in breast cancer. Expert Review of Anticancer Therapy, 14(2), 173-183. [More Information]
  • Ameratunga, M., Pavlakis, N., Gebski, V., Broad, A., Khasraw, M. (2014). Epidermal growth factor receptor-tyrosine kinase inhibitors in advanced squamous cell carcinoma of the lung: a meta-analysis. Asia-Pacific Journal of Clinical Oncology, 10(3), 273-278. [More Information]
  • Gupta, S., Tran, T., Luo, W., Phung, D., Kennedy, R., Broad, A., Campbell, D., Kipp, D., Singh, M., Khasraw, M., et al (2014). Machine-learning prediction of cancer survival: a retrospective study using electronic administrative records and a cancer registry. BMJ Open, 4(3), 1-7. [More Information]
  • Cosman, R., Brown, C., DeBraganca, K., Khasraw, M. (2014). Patterns of care in adult medulloblastoma: results of an international online survey. Journal of Neuro-Oncology, 120(1), 125-129. [More Information]
  • Harvey, S., Khasraw, M. (2013). Alternative targeted therapy for early HER2 positive breast cancer. Unknown, 2(1), 42-45.
  • Davis, J., Ahlberg, F., Berk, M., Ashley, D., Khasraw, M. (2013). Emerging pharmacotherapy for cancer patients with cognitive dysfunction. BMC Neurology, 13, 1-9. [More Information]
  • Lomax, A., Yap, S., Khasraw, M. (2013). Intraaortic metastases or intraarterial thrombus. International Journal of Case Reports and Images, 4(7), 368-371.
  • Khasraw, M., Yap, S., Ananda, S. (2013). Neuroendocrine neoplasms of the GI tract: the role of cytotoxic chemotherapy. Expert Review of Anticancer Therapy, 13(4), 451-459. [More Information]
  • Omuro, A., Chan, T., Abrey, L., Khasraw, M., Reiner, A., Kaley, T., DeAngelis, L., Lassman, A., Nolan, C., Gavrilovic, I., et al (2013). Phase II trial of continuous low-dose temozolomide for patients with recurrent malignant glioma. Neuro-Oncology, 15(2), 242-250. [More Information]
  • Domchek, S., Jhaveri, K., Patil, S., Stopfer, J., Hudis, C., Powers, J., Stadler, Z., Goldstein, L., Kauff, N., Khasraw, M., et al (2013). Risk of metachronous breast cancer after BRCA mutation-associated ovarian cancer. Cancer, 119(7), 1344-1348. [More Information]
  • Mustafa, B., Samaan, M., Langmead, L., Khasraw, M. (2013). Small bowel video capsule endoscopy: an overview. Expert Review of Gastroenterology and Hepatology, 7(4), 323-329. [More Information]
  • Sheet, S., Sheikha, A., Saeed, A., Ameen, H., Mohammed, S., Khasraw, M. (2012). Colorectal cancer: is the incidence rising in young Iraqi patients? Asia-Pacific Journal of Clinical Oncology, 8(4), 380-381. [More Information]
  • Khasraw, M., Bell, R., Dang, C. (2012). Epirubicin: Is it like doxorubicin in breast cancer? A clinical review. The Breast, 21(2), 142-149. [More Information]
  • Khasraw, M., Harvey, S., Bell, R. (2012). Hormonal Resistance in Breast Cancer: Evolving Treatment Strategies. Current Breast Cancer Reports, 4(1), 66-74. [More Information]
  • Khasraw, M., Holodny, A., Goldlust, S., DeAngelis, L. (2012). Intracranial hemorrhage in patients with cancer treated with bevacizumab: the Memorial Sloan-Kettering experience. Annals of Oncology, 23(2), 458-463. [More Information]
  • Khasraw, M., Bell, R. (2012). Primary systemic therapy in HER2-amplified breast cancer: a clinical review. Expert Review of Anticancer Therapy, 12(8), 1005-1013. [More Information]
  • Khasraw, M., Ashley, D., Wheeler, G., Berk, M. (2012). Using lithium as a neuroprotective agent in patients with cancer. BMC Medicine, 10, 1-7. [More Information]
  • Khasraw, M., Robson, M. (2011). Poly(ADP-ribose) polymerase inhibitors in breast cancer and other tumors: advances and challenges. Clinical Investigation, 1(11), 1545-1554. [More Information]
  • Khasraw, M., Brogi, E., Seidman, A. (2011). The Need to Examine Metastatic Tissue at the Time of Progression of Breast Cancer: Is Re-biopsy a Necessity or a Luxury? Current Oncology Reports, 13(1), 17-25. [More Information]
  • Khasraw, M., Lassman, A. (2010). Advances in the Treatment of Malignant Gliomas. Current Oncology Reports, 12(1), 26-33. [More Information]
  • Khasraw, M., Lassman, A., Wheeler, H., Pavlakis, N. (2010). Anti-angiogenic therapy for high grade glioma (Protocol). Cochrane Database of Systematic Reviews, 2010 (2), 1-9.
  • Murphy, C., Khasraw, M., Seidman, A. (2010). Holding back the sea: the role for maintenance chemotherapy in metastatic breast cancer. Breast Cancer Research and Treatment, 122(1), 177-179. [More Information]
  • Khasraw, M., Pavlakis, N., McCowatt, S., Underhill, C., Begbie, S., De Souza, P., Boyce, A., Parnis, F., Lim, V., Harvie, R., et al (2010). Multicentre phase I/II study of PI-88, a heparanase inhibitor in combination with docetaxel in patients with metastatic castrate-resistant prostate cancer. Annals of Oncology, 21(6), 1302-1307. [More Information]
  • Khasraw, M., Posner, J. (2010). Neurological complications of systemic cancer. The Lancet Neurology, 9(12), 1214-1227. [More Information]
  • Khasraw, M., Townsend, A., Price, T., Hart, J., Bell, D., Pavlakis, N. (2010). Objective radiological disease control with Sandostatin monotherapy in metastatic neuroendocrine tumours. Internal Medicine Journal, 40(6), 453-458. [More Information]
  • Khasraw, M., Faraj, H., Sheikha, A. (2010). Thrombocytopenia in Solid Tumors. European Journal of Clinical & Medical Oncology, 2(2), 1-4.
  • Khasraw, M., Atkinson, C., Van der Saag, D., Pavlakis, N., Guminski, A. (2009). Cardiac toxicity from sunitinib: Do we need to be more vigilant? Asia-Pacific Journal of Clinical Oncology, 5(4), 217-218. [More Information]
  • Khasraw, M., Baron-Hay, S. (2009). Immune thrombocytopenic purpura (ITP) and breast cancer. Does adjuvant therapy for breast cancer improve platelet counts in ITP? Annals of Oncology, 20(7), 1282-1283. [More Information]
  • Khasraw, M., Bell, D., Wheeler, H. (2009). Long-term use of temozolomide: Could you use temozolomide safely for life in gliomas? Journal of Clinical Neuroscience, 16(6), 854-855. [More Information]
  • Khasraw, M., Gill, A., Harrington, T., Pavlakis, N., Modlin, I. (2009). Management of Advanced Neuroendocrine Tumors With Hepatic Metastasis. Journal of Clinical Gastroenterology, 43(9), 838-47. [More Information]
  • Khasraw, M., Lassman, A. (2009). Neuro-oncology: late neurocognitive decline after radiotherapy for low-grade glioma. Nature Reviews Neurology, 5(12), 646-647. [More Information]
  • Khasraw, M., Marx, G. (2008). Chemotherapy in the Elderly. Cancer Forum, 32(1), 1-4.

2014

  • Khasraw, M., Ameratunga, M., Grant, R., Wheeler, H., Pavlakis, N. (2014). Antiangiogenic therapy for high-grade glioma. Cochrane Database of Systematic Reviews, 2014 (9), 1-42. [More Information]
  • Khasraw, M., Simeonovic, M., Grommes, C. (2014). Bevacizumab for the treatment of high-grade glioma. Expert Opinion on Biological Therapy, 12(8), 1101-1111. [More Information]
  • Khasraw, M., Ameratunga, M., Grommes, C. (2014). Bevacizumab for the treatment of high-grade glioma: an update after phase III trials. Expert Opinion on Biological Therapy, 14(5), 729-740. [More Information]
  • Hao-Wen, S., Morris, P., Patil, S., Khasraw, M. (2014). Brain metastases in breast cancer. Expert Review of Anticancer Therapy, 14(2), 173-183. [More Information]
  • Ameratunga, M., Pavlakis, N., Gebski, V., Broad, A., Khasraw, M. (2014). Epidermal growth factor receptor-tyrosine kinase inhibitors in advanced squamous cell carcinoma of the lung: a meta-analysis. Asia-Pacific Journal of Clinical Oncology, 10(3), 273-278. [More Information]
  • Gupta, S., Tran, T., Luo, W., Phung, D., Kennedy, R., Broad, A., Campbell, D., Kipp, D., Singh, M., Khasraw, M., et al (2014). Machine-learning prediction of cancer survival: a retrospective study using electronic administrative records and a cancer registry. BMJ Open, 4(3), 1-7. [More Information]
  • Cosman, R., Brown, C., DeBraganca, K., Khasraw, M. (2014). Patterns of care in adult medulloblastoma: results of an international online survey. Journal of Neuro-Oncology, 120(1), 125-129. [More Information]

2013

  • Harvey, S., Khasraw, M. (2013). Alternative targeted therapy for early HER2 positive breast cancer. Unknown, 2(1), 42-45.
  • Davis, J., Ahlberg, F., Berk, M., Ashley, D., Khasraw, M. (2013). Emerging pharmacotherapy for cancer patients with cognitive dysfunction. BMC Neurology, 13, 1-9. [More Information]
  • Lomax, A., Yap, S., Khasraw, M. (2013). Intraaortic metastases or intraarterial thrombus. International Journal of Case Reports and Images, 4(7), 368-371.
  • Khasraw, M., Yap, S., Ananda, S. (2013). Neuroendocrine neoplasms of the GI tract: the role of cytotoxic chemotherapy. Expert Review of Anticancer Therapy, 13(4), 451-459. [More Information]
  • Omuro, A., Chan, T., Abrey, L., Khasraw, M., Reiner, A., Kaley, T., DeAngelis, L., Lassman, A., Nolan, C., Gavrilovic, I., et al (2013). Phase II trial of continuous low-dose temozolomide for patients with recurrent malignant glioma. Neuro-Oncology, 15(2), 242-250. [More Information]
  • Domchek, S., Jhaveri, K., Patil, S., Stopfer, J., Hudis, C., Powers, J., Stadler, Z., Goldstein, L., Kauff, N., Khasraw, M., et al (2013). Risk of metachronous breast cancer after BRCA mutation-associated ovarian cancer. Cancer, 119(7), 1344-1348. [More Information]
  • Mustafa, B., Samaan, M., Langmead, L., Khasraw, M. (2013). Small bowel video capsule endoscopy: an overview. Expert Review of Gastroenterology and Hepatology, 7(4), 323-329. [More Information]

2012

  • Sheet, S., Sheikha, A., Saeed, A., Ameen, H., Mohammed, S., Khasraw, M. (2012). Colorectal cancer: is the incidence rising in young Iraqi patients? Asia-Pacific Journal of Clinical Oncology, 8(4), 380-381. [More Information]
  • Khasraw, M., Bell, R., Dang, C. (2012). Epirubicin: Is it like doxorubicin in breast cancer? A clinical review. The Breast, 21(2), 142-149. [More Information]
  • Khasraw, M., Harvey, S., Bell, R. (2012). Hormonal Resistance in Breast Cancer: Evolving Treatment Strategies. Current Breast Cancer Reports, 4(1), 66-74. [More Information]
  • Khasraw, M., Holodny, A., Goldlust, S., DeAngelis, L. (2012). Intracranial hemorrhage in patients with cancer treated with bevacizumab: the Memorial Sloan-Kettering experience. Annals of Oncology, 23(2), 458-463. [More Information]
  • Khasraw, M., Noy, A., Gilbert, M., Omuro, A. (2012). Neurological Complications of Non-Hodgkin Lymphoma. In Tracy Batchelor, Lisa M DeAngelis (Eds.), Lymphoma and Leukemia of the Nervous System, (pp. 267-286). New York: Springer Science+Business Media.
  • Khasraw, M., Khakoo, Y. (2012). Paraneoplastic Syndromes Affecting the Nervous System. In Kenneth F. Swaiman, Stephen Ashwal, Donna M Ferriero, Nina F Schor (Eds.), Swaiman's Pediatric Neurology: Principles and Practice, 5th Ed, (pp. 1388-1394). Canada: Elsevier Inc.
  • Khasraw, M., Bell, R. (2012). Primary systemic therapy in HER2-amplified breast cancer: a clinical review. Expert Review of Anticancer Therapy, 12(8), 1005-1013. [More Information]
  • Khasraw, M., Ashley, D., Wheeler, G., Berk, M. (2012). Using lithium as a neuroprotective agent in patients with cancer. BMC Medicine, 10, 1-7. [More Information]

2011

  • Khasraw, M., Robson, M. (2011). Poly(ADP-ribose) polymerase inhibitors in breast cancer and other tumors: advances and challenges. Clinical Investigation, 1(11), 1545-1554. [More Information]
  • Khasraw, M., Brogi, E., Seidman, A. (2011). The Need to Examine Metastatic Tissue at the Time of Progression of Breast Cancer: Is Re-biopsy a Necessity or a Luxury? Current Oncology Reports, 13(1), 17-25. [More Information]

2010

  • Khasraw, M., Lassman, A. (2010). Advances in the Treatment of Malignant Gliomas. Current Oncology Reports, 12(1), 26-33. [More Information]
  • Khasraw, M., Lassman, A., Wheeler, H., Pavlakis, N. (2010). Anti-angiogenic therapy for high grade glioma (Protocol). Cochrane Database of Systematic Reviews, 2010 (2), 1-9.
  • Murphy, C., Khasraw, M., Seidman, A. (2010). Holding back the sea: the role for maintenance chemotherapy in metastatic breast cancer. Breast Cancer Research and Treatment, 122(1), 177-179. [More Information]
  • Khasraw, M., Pavlakis, N., McCowatt, S., Underhill, C., Begbie, S., De Souza, P., Boyce, A., Parnis, F., Lim, V., Harvie, R., et al (2010). Multicentre phase I/II study of PI-88, a heparanase inhibitor in combination with docetaxel in patients with metastatic castrate-resistant prostate cancer. Annals of Oncology, 21(6), 1302-1307. [More Information]
  • Khasraw, M., Posner, J. (2010). Neurological complications of systemic cancer. The Lancet Neurology, 9(12), 1214-1227. [More Information]
  • Khasraw, M., Townsend, A., Price, T., Hart, J., Bell, D., Pavlakis, N. (2010). Objective radiological disease control with Sandostatin monotherapy in metastatic neuroendocrine tumours. Internal Medicine Journal, 40(6), 453-458. [More Information]
  • Khasraw, M., Faraj, H., Sheikha, A. (2010). Thrombocytopenia in Solid Tumors. European Journal of Clinical & Medical Oncology, 2(2), 1-4.

2009

  • Khasraw, M., Atkinson, C., Van der Saag, D., Pavlakis, N., Guminski, A. (2009). Cardiac toxicity from sunitinib: Do we need to be more vigilant? Asia-Pacific Journal of Clinical Oncology, 5(4), 217-218. [More Information]
  • Khasraw, M., Baron-Hay, S. (2009). Immune thrombocytopenic purpura (ITP) and breast cancer. Does adjuvant therapy for breast cancer improve platelet counts in ITP? Annals of Oncology, 20(7), 1282-1283. [More Information]
  • Khasraw, M., Bell, D., Wheeler, H. (2009). Long-term use of temozolomide: Could you use temozolomide safely for life in gliomas? Journal of Clinical Neuroscience, 16(6), 854-855. [More Information]
  • Khasraw, M., Gill, A., Harrington, T., Pavlakis, N., Modlin, I. (2009). Management of Advanced Neuroendocrine Tumors With Hepatic Metastasis. Journal of Clinical Gastroenterology, 43(9), 838-47. [More Information]
  • Khasraw, M., Lassman, A. (2009). Neuro-oncology: late neurocognitive decline after radiotherapy for low-grade glioma. Nature Reviews Neurology, 5(12), 646-647. [More Information]

2008

  • Khasraw, M., Marx, G. (2008). Chemotherapy in the Elderly. Cancer Forum, 32(1), 1-4.

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