Dr Najla Nasr

Senior Research Fellow
Westmead Millennium Institute for Medical Research, Westmead Clinical School

Telephone 02 9845 9118

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Selected grants

2015

  • The Role of Dendritic Cells in Sexual Transmission of HIV and Viral Reservoir Formation; Harman A, Cunningham A, Palmer S, Kim M, Nasr N; National Health and Medical Research Council (NHMRC)/Project Grants.

Selected publications

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Book Chapters

  • Nasr, N., Harman, A., Turville, S., Cunningham, A. (2014). HIV infection of dendritic cells. In Elisa Vincenzi, Guido Poli (Eds.), Human Retroviruses: Method and Protocols, (pp. 221-232). New York: Humana Press. [More Information]
  • Cunningham, A., Harman, A., Kim, M., Nasr, N., Lai, J. (2013). Immunobiology of Dendritic Cells and the Influence of HIV Infection. In Li Wu, Olivier Schwartz (Eds.), HIV Interactions with Dendritic Cells: Infection and Immunity, (pp. 1-44). New York, USA: Springer Science + Business Media.
  • Cunningham, A., Harman, A., Kim, M., Nasr, N., Lai, J. (2013). Immunobiology of Dendritic Cells and the Influence of HIV Infection. In Li Wu, Olivier Schwartz (Eds.), HIV Interactions with Dendritic Cells: Infection and Immunity, (pp. 1-44). New York, USA: Springer Science + Business Media.

Journals

  • Harman, A., Bye, C., Nasr, N., Sandgren, K., Kim, M., Mercier, S., Botting, R., Lewin, S., Cunningham, A., Cameron, P. (2013). Identification of Lineage Relationships and Novel Markers of Blood and Skin Human Dendritic Cells. Journal of Immunology, 190(1), 66-79. [More Information]
  • Cunningham, A., Harman, A., Nasr, N. (2013). Initial HIV mucosal infection and dendritic cells. EMBO Molecular Medicine (Online), 5(5), 658-660. [More Information]
  • Mercier, S., Donaghy, H., Botting, R., Turville, S., Harman, A., Nasr, N., Ji, H., Kusebauch, U., Mendoza, L., Shteynberg, D., Cunningham, A., et al (2013). The Microvesicle Component of HIV-1 Inocula Modulates Dendritic Cell Infection and Maturation and Enhances Adhesion to and Activation of T Lymphocytes. PLoS Pathogens, 9(10), 1-18. [More Information]
  • Harman, A., Kim, M., Nasr, N., Sandgren, K., Cameron, P. (2013). Tissue dendritic cells as portals for HIV entry. Reviews in Medical Virology, 23(5), 319-333. [More Information]
  • Nasr, N., Maddocks, S., Turville, S., Harman, A., Woolger, N., Helbig, K., Wilkinson, J., Bye, C., Wright, T., Rambukwelle, D., Donaghy, H., Cunningham, A., et al (2012). HIV-1 infection of human macrophages directly induces viperin which inhibits viral production. Blood, 120(4), 778-788. [More Information]
  • Harman, A., Lai, J., Turville, S., Samarajiwa, S., Gray, L., Marsden, V., Mercier, S., Jones, K., Nasr, N., Rustagi, A., Cunningham, A., et al (2011). HIV infection of dendritic cells subverts the interferon induction pathway via IRF1 and inhibits type 1 interferon production. Blood, 118(2), 298-308. [More Information]
  • Huch, J., Cunningham, A., Arvin, A., Nasr, N., Santegoets, S., Slobedman, E., Slobedman, B., Abendroth, A. (2010). Impact of varicella-zoster virus on dendritic cell subsets in human skin during natural infection. Journal of Virology, 84(8), 4060-4072. [More Information]
  • Cunningham, A., Abendroth, A., Jones, C., Nasr, N., Turville, S. (2010). Viruses and Langerhans cells. Immunology and Cell Biology, 88(4), 416-423. [More Information]
  • Harman, A., Kraus, M., Bye, C., Byth Wilson, K., Turville, S., Tang, O., Mercier, S., Nasr, N., Stern, J., Slobedman, B., Cunningham, A., et al (2009). HIV-1-infected dendritic cells show 2 phases of gene expression changes, with lysosomal enzyme activity decreased during the second phase. Blood, 114(1), 85-94. [More Information]
  • Gray, L., Sterjovski, J., Churchill, M., Ellery, P., Nasr, N., Lewin, S., Crowe, S., Wesselingh, S., Cunningham, A., Gorry, P. (2005). Uncoupling coreceptor usage of human immunodeficiency virus type 1 (HIV-1) from macrophage tropism reveals biological properties of CCR5-restricted HIV-1 isolates from patients with acquired immunodeficiency syndrome. Virology, 337(2), 384-398.
  • Ewart, G., Nasr, N., Naif, H., Cox, G., Cunningham, A., Gage, P. (2004). Potential New Anti-Human Immunodeficiency Virus Type 1 Compounds Depress Virus Replication In Cultured Human Macrophages. Antimicrobial Agents and Chemotherapy, 48(6), 2325-2330.
  • Naif, H., Cunningham, A., Alali, M., Nasr, N., Buhler, M., Stewart, G., Li, S., Schols, D., de Clercq, E. (2002). A Human Immunodeficiency Virus Type 1 Isolate from an Infected Person Homozygous for CCR5/\32 Exhibits Dual Tropism by Infecting Macrophages and MT2 Cells via CXCR4. Journal of Virology, 76(7), 3114-3124.
  • Qi, J., Stevens, R., Wadley, R., Collins, A., Cooley, M., Naif, H., Nasr, N., Cunningham, A., Katsoulotos, G., Wanigasekara-Mohotti, Y., Roufogalis, B., et al (2002). IL-16 Regulation of Human Mast Cells/Basophils and Their Susceptability to HIV-1. Journal of Immunology, 168(8), 4127-4134.

2014

  • Nasr, N., Harman, A., Turville, S., Cunningham, A. (2014). HIV infection of dendritic cells. In Elisa Vincenzi, Guido Poli (Eds.), Human Retroviruses: Method and Protocols, (pp. 221-232). New York: Humana Press. [More Information]

2013

  • Harman, A., Bye, C., Nasr, N., Sandgren, K., Kim, M., Mercier, S., Botting, R., Lewin, S., Cunningham, A., Cameron, P. (2013). Identification of Lineage Relationships and Novel Markers of Blood and Skin Human Dendritic Cells. Journal of Immunology, 190(1), 66-79. [More Information]
  • Cunningham, A., Harman, A., Kim, M., Nasr, N., Lai, J. (2013). Immunobiology of Dendritic Cells and the Influence of HIV Infection. In Li Wu, Olivier Schwartz (Eds.), HIV Interactions with Dendritic Cells: Infection and Immunity, (pp. 1-44). New York, USA: Springer Science + Business Media.
  • Cunningham, A., Harman, A., Kim, M., Nasr, N., Lai, J. (2013). Immunobiology of Dendritic Cells and the Influence of HIV Infection. In Li Wu, Olivier Schwartz (Eds.), HIV Interactions with Dendritic Cells: Infection and Immunity, (pp. 1-44). New York, USA: Springer Science + Business Media.
  • Cunningham, A., Harman, A., Nasr, N. (2013). Initial HIV mucosal infection and dendritic cells. EMBO Molecular Medicine (Online), 5(5), 658-660. [More Information]
  • Mercier, S., Donaghy, H., Botting, R., Turville, S., Harman, A., Nasr, N., Ji, H., Kusebauch, U., Mendoza, L., Shteynberg, D., Cunningham, A., et al (2013). The Microvesicle Component of HIV-1 Inocula Modulates Dendritic Cell Infection and Maturation and Enhances Adhesion to and Activation of T Lymphocytes. PLoS Pathogens, 9(10), 1-18. [More Information]
  • Harman, A., Kim, M., Nasr, N., Sandgren, K., Cameron, P. (2013). Tissue dendritic cells as portals for HIV entry. Reviews in Medical Virology, 23(5), 319-333. [More Information]

2012

  • Nasr, N., Maddocks, S., Turville, S., Harman, A., Woolger, N., Helbig, K., Wilkinson, J., Bye, C., Wright, T., Rambukwelle, D., Donaghy, H., Cunningham, A., et al (2012). HIV-1 infection of human macrophages directly induces viperin which inhibits viral production. Blood, 120(4), 778-788. [More Information]

2011

  • Harman, A., Lai, J., Turville, S., Samarajiwa, S., Gray, L., Marsden, V., Mercier, S., Jones, K., Nasr, N., Rustagi, A., Cunningham, A., et al (2011). HIV infection of dendritic cells subverts the interferon induction pathway via IRF1 and inhibits type 1 interferon production. Blood, 118(2), 298-308. [More Information]

2010

  • Huch, J., Cunningham, A., Arvin, A., Nasr, N., Santegoets, S., Slobedman, E., Slobedman, B., Abendroth, A. (2010). Impact of varicella-zoster virus on dendritic cell subsets in human skin during natural infection. Journal of Virology, 84(8), 4060-4072. [More Information]
  • Cunningham, A., Abendroth, A., Jones, C., Nasr, N., Turville, S. (2010). Viruses and Langerhans cells. Immunology and Cell Biology, 88(4), 416-423. [More Information]

2009

  • Harman, A., Kraus, M., Bye, C., Byth Wilson, K., Turville, S., Tang, O., Mercier, S., Nasr, N., Stern, J., Slobedman, B., Cunningham, A., et al (2009). HIV-1-infected dendritic cells show 2 phases of gene expression changes, with lysosomal enzyme activity decreased during the second phase. Blood, 114(1), 85-94. [More Information]

2005

  • Gray, L., Sterjovski, J., Churchill, M., Ellery, P., Nasr, N., Lewin, S., Crowe, S., Wesselingh, S., Cunningham, A., Gorry, P. (2005). Uncoupling coreceptor usage of human immunodeficiency virus type 1 (HIV-1) from macrophage tropism reveals biological properties of CCR5-restricted HIV-1 isolates from patients with acquired immunodeficiency syndrome. Virology, 337(2), 384-398.

2004

  • Ewart, G., Nasr, N., Naif, H., Cox, G., Cunningham, A., Gage, P. (2004). Potential New Anti-Human Immunodeficiency Virus Type 1 Compounds Depress Virus Replication In Cultured Human Macrophages. Antimicrobial Agents and Chemotherapy, 48(6), 2325-2330.

2002

  • Naif, H., Cunningham, A., Alali, M., Nasr, N., Buhler, M., Stewart, G., Li, S., Schols, D., de Clercq, E. (2002). A Human Immunodeficiency Virus Type 1 Isolate from an Infected Person Homozygous for CCR5/\32 Exhibits Dual Tropism by Infecting Macrophages and MT2 Cells via CXCR4. Journal of Virology, 76(7), 3114-3124.
  • Qi, J., Stevens, R., Wadley, R., Collins, A., Cooley, M., Naif, H., Nasr, N., Cunningham, A., Katsoulotos, G., Wanigasekara-Mohotti, Y., Roufogalis, B., et al (2002). IL-16 Regulation of Human Mast Cells/Basophils and Their Susceptability to HIV-1. Journal of Immunology, 168(8), 4127-4134.

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