Professor Nicholas King
Professor of Viral Immunopathology
D06 - Blackburn Building
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We are interested in the neurotropic flavivirus, West Nile virus, and how our immune response, in trying to get rid of virus infection, lethally damages the host nervous system in this response.
We are studying the pathogenesis of West Nile virus encephalitis to understand which components cause lethal damage in the brain and which are crucial for virus clearance.
We are also investigating early immune responses to infection in specialised organs and sites, including the brain, the skin, the genitourinary tract, the embryo and the eye, as being the key to modulating this process before damage occurs.
Current national competitive grants*
Role of Inflammation in Diabetic Cardiomyopathy
Twigg S, King N, McLennan S
NHMRC Project Grants ($476,325 over 3 years)
Immune modifying particles - a novel therapeutic strategy to treat West Nile Virus encephalitis
King N, Getts D
NHMRC Project Grants ($532,260 over 3 years)
* Grants administered through the University of Sydney
PhD and Masters' project opportunities
Honours project opportunities
Changes in gene expression in neurons and microglia in WNV encephalitis
Infiltrating leukocytes in WNV encephalitis - their role in mortality
The role of mucosal dendritic cells in controlling virus infection in epithelium
Why isn't the foreign embryo rejected by the mother? The role of infection in alerting the mother's immune system to her embryo.
The role of monocyte/dendritic cells in initiating WNV immune responses.
The role of microparticles in the immune response to WNV
Germany. (University of Muenster) Collaborative Research into diagnostic imaging approaches to viral encephalitis.