Associate Professor Peter Liu

Associate Professor
Sleep Medicine, Central Clinical School
Woolcock Institute of Medical Research

Telephone +61 2 9114 0007
Fax +61 2 9114 0465

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Selected grants

2012

  • Senior Research Fellowship A; Liu P; National Health and Medical Research Council (NHMRC)/Career Awards: Research Fellowships.

2010

  • Embla (Titanium PSG System); Grunstein R, Liu P, Robinson P, Simpson S; National Health and Medical Research Council (NHMRC)/Equipment Grants.
  • The effect of CPAP on erectile and endothelial dysfunction in impotent men with obstructive sleep apnea; Wong K, Ng M, Liu P, Yee B; National Health and Medical Research Council (NHMRC)/Project Grants.

2009

  • CCRE in Interdisciplinary Sleep Health; Grunstein R, Anderson C, Liu P, Cistulli P, Glozier N, Armour C, Robinson P, Marks G; National Health and Medical Research Council (NHMRC)/Centre of Clinical Research Excellence.
  • Sound and Vibration Measurement and Analysis System (SavTech); Grunstein R, Cistulli P, Liu P; National Health and Medical Research Council (NHMRC)/Equipment Grants.

2008

  • Liquid Chromatography Tandem Mass Spectrometry Steroid Analysis Facility; Norman R, Risbridger G, Liu P, Handelsman D; Australian Research Council (ARC)/Linkage Infrastructure, Equipment and Facilities (LIEF).
  • Liquid Chromatography Tandem Mass Spectrometry Steroid Analysis Facility; Handelsman D, Norman R, Risbridger G, Liu P; Australian Research Council (ARC)/Linkage Infrastructure, Equipment and Facilities (LIEF).
  • Metabolic and Psychomotor changes after Continous Positive Airway Pressure treatment for Obstructive Sleep Apnea; Liu P, Yee B, Phillips C, Berend N; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Obstructibe Sleep Apnea and Androgen Dysregulation; Liu P, Grunstein R, Handelsman D; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Androgen deficiency in chronic disease; Liu P; National Health and Medical Research Council (NHMRC)/A Healthy Start to Life for All Australians.

2007

  • Metabolic and Psychomotor changes after Continuous Positive Airway Pressure treatment for Obstructive Sleep Apnea; Liu P; University of Sydney/Bridging Support.

2003

  • Effects of anabolic hormones and exercise on male ageing; Liu P; National Health and Medical Research Council (NHMRC)/Early Career Fellowships (ECF).
  • Effects of anabolic hormones and exercise on male ageing; Liu P; National Health and Medical Research Council (NHMRC)/Early Career Fellowships (ECF).

Selected publications

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Book Chapters

  • Yee, B., Liu, P., Phillips, C., Grunstein, R. (2012). Neuroendocrine Aspects of Sleep Apnea. In Allan I. Pack (Eds.), Sleep Apnea: Pathogenesis, Diagnosis and Treatment, (pp. 286-299). London: Informa Healthcare.
  • Liu, P. (2007). Hormonal induction of spermatogenesis in males with hypogonadotropic hypogonadism. In Fouad R. Kandeel (Eds.), Male Reproductive Dysfunction: Pathophysiology and treatment, (pp. 337-348). New York: Informa Healthcare.
  • Liu, P., GOOREN, L., Handelsman, D. (2007). Impact of systemic disease on male sexual function. In Fouad R.Kandeel,Tom F.Lue,Jon L.Pryor,Ronald S.Swerdloff (Eds.), Male Sexual Dysfunction: Pathophysiology and Treatment, (pp. 155-176). New York: Informa Healthcare.
  • Seibel, M., Meier, C., Liu, P., Handelsman, D. (2006). Sex steroids and skeletal health in men. In Lane N (Eds.), Osteoporosis and the Osteoporosis of Rheumatic Diseases, (pp. 145-156). Philadelphia: Mosby Elsevier.
  • Liu, P., Handelsman, D. (2004). Androgen therapy in non-gonadal disease. In Nieschlag E, Behre HM (Eds.), Testosterone: Action, Deficiency and Substitution, (pp. 445-495). United Kingdom: Cambridge University Press.
  • Liu, P., Takahashi, P., Nehra, A., Pincus, S., Keenan, D., Veldhuis, J. (2004). Neuroendocrine aging: Pituitary-testis: LH/FSH/Prolactin. In George Adelman and Barry H.Smith (Eds.), New Encyclopedia of Neuroscience. Oxford: Elsevier B.V.
  • Liu, P., Handelsman, D. (2003). Hormonal therapy of the infertile man. In Meikle (Eds.), Endocrine Replacement Therapy in Clinical Practice, (pp. 453-467). New Jersey: Humana Press.
  • Liu, P., Handelsman, D. (2003). Hypogonadism In Men With Chronic Renal Failure. In SJ Winters (Eds.), Contemporary Endocrinology: Male Hypogonadism: Basic, Clinical and Therapeutic Principles,, (pp. 225-244). Totowa NJ: Humana Press.
  • Liu, P., Handelsman, D. (2001). Research Summaries Book.

Journals

  • Hoyos, C., Sullivan, D., Liu, P. (2013). Effect of CPAP on the metabolic syndrome: a randomised sham-controlled study. Thorax, 68(6), 588-589. [More Information]
  • Simpson, P., Hoyos, C., Celermajer, D., Liu, P., Ng, M. (2013). Effects of continuous positive airway pressure on endothelial function and circulating progenitor cells in obstructive sleep apnoea: A randomised sham-controlled study. International Journal of Cardiology, 168(3), 2042-2048. [More Information]
  • Killick, R., Wang, D., Hoyos, C., Yee, B., Grunstein, R., Liu, P. (2013). The effects of testosterone on ventilatory responses in men with obstructive sleep apnoea: a randomised, placebo-controlled trial. Journal of Sleep Research, 22(3), 331-336. [More Information]
  • Brillante, R., Laks, L., Cossa, G., Peters, M., Liu, P. (2012). An Overnight Increase in CO(2) Predicts Mortality in Sleep Disordered Breathing. Respirology, 17(6), 933-939. [More Information]
  • Hoyos, C., Yee, B., Phillips, C., Machan, E., Grunstein, R., Liu, P. (2012). Body compositional and cardiometabolic effects of testosterone therapy in obese men with severe obstructive sleep apnea: a randomised placebo-controlled trial. European Journal of Endocrinology, 167(4), 531-541. [More Information]
  • Hoyos, C., Killick, R., Yee, B., Phillips, C., Grunstein, R., Liu, P. (2012). Cardiometabolic changes after continuous positive airway pressure for obstructive sleep apnoea: a randomised sham-controlled study. Thorax, 67(12), 1081-1089. [More Information]
  • Veldhuis, J., Liu, P., Takahashi, P., Keenan, D. (2012). Dynamic testosterone responses to near-physiological LH pulses are determined by the time pattern of prior intravenous LH infusion. American Journal of Physiology: Endocrinology and Metabolism (online), 303(6), e720-e728. [More Information]
  • Sivam, S., Phillips, C., Trenell, M., Yee, B., Liu, P., Wong, K., Grunstein, R. (2012). Effects of 8 weeks of continuous positive airway pressure on abdominal adiposity in obstructive sleep apnoea. The European Respiratory Journal, 40(4), 913-918. [More Information]
  • Hoyos, C., Killick, R., Yee, B., Grunstein, R., Liu, P. (2012). Effects of testosterone therapy on sleep and breathing in obese men with severe obstructive sleep apnoea: a randomized placebo-controlled trial. Clinical Endocrinology, 77(4), 599-607. [More Information]
  • Killick, R., Banks, S., Liu, P. (2012). Implications of Sleep Restriction and Recovery on Metabolic Outcomes. Journal of Clinical Endocrinology and Metabolism, 97(11), 3876-3890. [More Information]
  • Veldhuis, J., Liu, P., Keenan, D., Takahashi, P. (2012). Older men exhibit reduced efficacy of and heightened potency downregulation by intravenous pulses of recombinant human LH: a study in 92 healthy men. American Journal of Physiology: Endocrinology and Metabolism (online), 302(1), E117-E122. [More Information]
  • Brillante, R., Cossa, G., Liu, P., Laks, L. (2012). Rapid eye movement and slow-wave sleep rebound after one night of continuous positive airway pressure for obstructive sleep apnoea. Respirology, 17(3), 547-553. [More Information]
  • Phillips, C., Yee, B., Marshall, N., Liu, P., Sullivan, D., Grunstein, R. (2011). Continuous Positive Airway Pressure Reduces Postprandial Lipidemia in Obstructive Sleep Apnea. A Randomised, Placebo Controlled Crossover Trial. American Journal of Respiratory and Critical Care Medicine, 184(3), 355-361. [More Information]
  • Ilani, N., Liu, P., Swerdloff, R., Wang, C. (2011). Does ethnicity matter in male hormonal contraceptive efficacy? Asian Journal of Andrology, 13(4), 579-584. [More Information]
  • Swerdloff, R., Lue, Y., Liu, P., Erkkila, K., Wang, C. (2011). Mouse model for men with klinefelter syndrome: a multifaceted fit for a complex disorder. Acta Paediatrica: Nurturing the Child, 100(6), 892-899. [More Information]
  • Wang, X., Keenan, D., Pincus, S., Liu, P., Veldhuis, J. (2011). Oscillations in joint synchrony of reproductive hormones in healthy men. American Journal of Physiology: Endocrinology and Metabolism, 301(6), E1163-E1173. [More Information]
  • Marshall, N., Wong, K., Liu, P., Grunstein, R. (2011). Smoking is not better for you than sleep apnea. The Journal of Clinical Sleep Medicine, 7(3), 317-317. [More Information]
  • Veldhuis, J., Takahashi, P., Keenan, D., Liu, P., Mielke, K., Weist, S. (2010). Age disrupts androgen receptor-modulated negative feedback in the gonadal axis in healthy men. American Journal of Physiology: Endocrinology and Metabolism, 299, E675-E682. [More Information]
  • Liu, P., Kalak, R., Lue, Y., Jia, Y., Erkkila, K., Zhou, H., Seibel, M., Wang, C., Swerdloff, R., Dunstan, C. (2010). Genetic and Hormonal Control of Bone Volume, Architecture, and Remodeling in XXY Mice. Journal of Bone and Mineral Research, 25(10), 2148-2154. [More Information]
  • Liu, P., Erkkila, K., Lue, Y., Jentsch, D., Schwarcz, M., Abuyounes, D., Hikim, A., Wang, C., Lee, P., Swerdloff, R. (2010). Genetic, hormonal, and metabolomic influences on social behavior and sex preference of XXY mice. American Journal of Physiology: Endocrinology and Metabolism, 299(3), E446-E455. [More Information]
  • Williams, S., Marshall, N., Kennerson, M., Rogers, N., Liu, P., Grunstein, R. (2010). Modafinil Effects during Acute Continuous Positive Airway Withdrawal: A Randomized Crossover Double-Blind Placebo-controlled Trial. American Journal of Respiratory and Critical Care Medicine, 181(8), 825-831. [More Information]
  • Fennell, C., Sartorius, G., Ly, L., Turner, L., Liu, P., Conway, A., Handelsman, D. (2010). Randomized cross-over clinical trial of injectable vs. implantable depot testosterone for maintenance of testosterone replacement therapy in androgen deficient men. Clinical Endocrinology, 73(1), 102-109. [More Information]
  • Liu, P., Swerdloff, R., Wang, C. (2010). Recent methodological advances in male hormonal contraception. Contraception, 82(5), 471-475. [More Information]
  • Ip, F., di Pierro, I., Brown, R., Cunningham, I., Handelsman, D., Liu, P. (2010). Trough serum testosterone predicts the development of polycythemia in hypogonadal men treated for up to 21 years with subcutaneous testosterone pellets. European Journal of Endocrinology, 162(2), 385-390. [More Information]
  • Kalak, R., Zhou, H., Street, J., Day, R., Modzelewski, J., Spies, C., Liu, P., Li, G., Dunstan, C., Seibel, M. (2009). Endogenous glucocorticoid signaling in osteoblasts is necessary to maintain normal bone structure in mice. Bone, 45(1), 61-67. [More Information]
  • Liu, P., Gordon Baker, H., Jayadev, V., Zacharin, M., Conway, A., Handelsman, D. (2009). Induction of spermatogenesis and fertility during gonadotropin treatment of gonadotropin deficient infertile men: predictors of fertility outcome. Journal of Clinical Endocrinology and Metabolism, 94(3), 801-808. [More Information]
  • Marshall, N., Wong, K., Phillips, C., Liu, P., Knuiman, M., Grunstein, R. (2009). Is sleep apnea an independent risk factor for prevalent and incident diabetes in the Busselton Health Study? The Journal of Clinical Sleep Medicine, 5(1), 15-20. [More Information]
  • Liu, P., Keenan, D., Kok, P., Padmanabhan, V., O'Byrne, K., Veldhuis, J. (2009). Sensitivity and specificity of pulse detection using a new deconvolution method. American Journal of Physiology: Endocrinology and Metabolism, 297(2), E538-E544. [More Information]
  • Veldhuis, J., Keenan, D., Liu, P., Iranmanesh, A., Takahashi, P., Nehra, A. (2009). The aging male hypothalamic-pituitary-gonadal axis: Pulsatility and feedback. Molecular And Cellular Endocrinology, 299(1), 14-22. [More Information]
  • Liu, P., Swerdloff, R., Anawalt, B., Anderson, R., Bremner, W., Elliesen, J., Gu, Y., Kersemaekers, W., McLachlan, R., Meriggiola, M., Handelsman, D., et al (2008). Determinants of the Rate and Extent of Spermatogenic Suppression during Hormonal Male Contraception: An Integrated Analysis. Journal of Clinical Endocrinology and Metabolism, 93(5), 1774-1783. [More Information]
  • Liu, P., McLachlan, R. (2008). Male hormonal contraception: so near and yet so far. Journal of Clinical Endocrinology and Metabolism, 93(7), 2474-2476. [More Information]
  • Marshall, N., Wong, K., Liu, P., Cullen, S., Knuiman, M., Grunstein, R. (2008). Sleep Apnea as an Independent Risk Factor for All-Cause Mortality: The Busselton Health Study. Sleep, 31(8), 1079-1085. [More Information]
  • Grunstein, R., Phillips, C., Liu, P. (2008). Sleep apnea--past, present, future. Sleep Medicine Reviews, 12(1), 1-4. [More Information]
  • Aaltonen, P., Amory, J., Anderson, R., Behre, H., Bialy, G., Blithe, D., Bone, W., Bremner, W., Colvard, D., Handelsman, D., Liu, P., et al (2007). 10th Summit Meeting consensus: recommendations for regulatory approval for hormonal male contraception. Journal Of Andrology, 28(3), 362-363. [More Information]
  • Liu, P., Iranmanesh, A., Keenan, D., Pincus, S., Veldhuis, J. (2007). A Noninvasive Measure of Negative-Feedback Strength, Approximate Entropy, Unmasks Strong Diurnal Variations in the Regularity of Luteinizing Hormone Secretion. American Journal of Physiology: Endocrinology and Metabolism, 293(5), E1409-E1415. [More Information]
  • Liu, P., Beilin, J., Meier, C., Nguyen, T., Center, J., Leedman, P., Seibel, M., Eisman, J., Handelsman, D. (2007). Age-Related Changes in Serum Testosterone and Sex Hormone Binding Globulin in Australian Men: Longitudinal Analyses of Two Geographically Separate Regional Cohorts. Journal of Clinical Endocrinology and Metabolism, 92(9), 3599-3603. [More Information]
  • Liu, P., Caterson, I., Grunstein, R., Handelsman, D. (2007). Androgens, Obesity, and Sleep-Disordered Breathing in Men. Endocrinology and Metabolism Clinics of North America, 36(2), 349-363. [More Information]
  • Yee, B., Buchanan, P., Mahadev, S., Banerjee, D., Liu, P., Phillips, C., Loughnan, G., Steinbeck, K., Grunstein, R. (2007). Assessment of sleep and breathing in adults with Prader-Willi syndrome: a case control series. The Journal of Clinical Sleep Medicine, 3(7), 713-718. [More Information]
  • Chung, T., Kelleher, S., Liu, P., Conway, A., Kritharides, L., Handelsman, D. (2007). Effects of Testosterone and Nandrolone on Cardiac Function: A Randomized, Placebo-Controlled Study. Clinical Endocrinology, 66(2), 235-245. [More Information]
  • Lue, Y., Erkkilla, K., Liu, P., Wang, C., Hikim, A., Swerdloff, R. (2007). Fate of bone marrow cells transplanted into the testis. The American Journal of Pathology: cellular and molecular biology of disease, 170(3), 899-908.
  • Caroll, B., Cassidy, F., Naftolowitz, D., Tatham, N., Wilson, W., Iranmanesh, A., Liu, P., Veldhuis, J. (2007). Pathophysiology of hypercortisolism in depression. Acta Psychiatrica Scandinavica, 115(433), 90-103.
  • Liu, P., Yee, B., Phillips, C., Grunstein, R. (2007). Sleep Apnea and Neuroendocrine Function. Sleep Medicine Clinics, 2(2), 225-236.
  • Liu, P., Takahashi, P., Roebuck, P., Veldhuis, J. (2006). Age or factors associated with aging attenuate testosterone's concentration dependant enhancement of the regularity of luteinizing hormone secretion in healthy men. Journal of Clinical Endocrinology and Metabolism, 91(10), 4077-4084. [More Information]
  • Liu, P., Pincus, S., Takahashi, P., Roebuck, P., Iranmanesh, A., Keenan, D., Veldhuis, J. (2006). Aging attenuates both the regularity and joint synchrony of LH and testosterone secretion in normal men: analyses via a model of graded GnRH receptor blockade. American Journal of Physiology: Endocrinology and Metabolism, 290(1), E34-E41. [More Information]
  • Keenan, D., Takahashi, P., Liu, P., Roebuck, P., Nehra, A., Iranmanesh, A., Veldhuis, J. (2006). An ensemble model of the male gonadal axis: illustrative application in aging men. Endocrinology, 147(6), 2817-2828. [More Information]
  • Liu, P., Wang, C., Swerdloff, R. (2006). Does individual responce to androgen replacement therapy affect bone density? Nature clinical practice: Endocrinology and metabolism, , 76-77. [More Information]
  • Liu, P., Handelsman, D. (2006). Early markers in metabolic syndrome in non overweight, middle aged men. Nature Clinical Practice Oncology, 3, 524-525.
  • Liu, P., Handelsman, D. (2006). Early markers of metabolic syndrome in nonoverweight, middle-aged men. Nature Clinical Practice Urology, 3(10), 524-5. [More Information]
  • Handelsman, D., Liu, P. (2006). Editorial: Klinefelter's Syndrome: A Microcosm of Male Reproductive Health. Journal of Clinical Endocrinology and Metabolism, 91(4), 1220-1222.
  • Christian, R., Liu, P., Harrington, S., Ruan, M., Miller, V., Fitzpatrick, L. (2006). Intimal Estrogen Receptor (ER)β, but not ERα expression, is correlated with coronary calcification and atherosclerosis in pre- and postmenopausal women. Journal of Clinical Endocrinology and Metabolism, 91(7), 2713-2720. [More Information]
  • Liu, P., Swerdloff, R., Christenson, P., Handelsman, D., Wang, C. (2006). Rate, extent, and modifiers of spermatogenic recovery after hormonal male contraception: an integrated analysis. The Lancet, 367(9520), 1412-1420.
  • Liu, P., Hoey, K., Mielke, K., Veldhuis, J., Khosla, S. (2005). A randomized placebo-controlled trial of short-term graded transdermal estradiol in healthy gonadotropin-releasing hormone agonist-suppressed pre- and postmenopausal women: effects on serum markers of bone turnover, insulin-like growth factor-I, and osteo. Journal of Clinical Endocrinology and Metabolism, 90(4), 1953-60. [More Information]
  • Liu, P., Takahashi, P., Roebuck, P., Iranmanesh, A., Veldhuis, J. (2005). Age-specific changes in the regulation of LH-dependent testosterone secretion: assessing responsiveness to varying endogenous gonadotropin output in normal men. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology (Print), 289(3), R721-R728. [More Information]
  • Liu, P., Takahashi, P., Roebuck, D., Iranmanesh, A., Veldhuis, J. (2005). Aging in healthy men impairs recombinant human luteinizing hormone (LH)-stimulated testosterone secretion monitored under a two-day intravenous pulsatile LH clamp. Journal of Clinical Endocrinology and Metabolism, 90(10), 5544-5550. [More Information]
  • Liu, P., Pincus, S., Keenan, D., Roelfsema, F., Veldhuis, J. (2005). Analysis of bidirectional pattern synchrony of concentration-secretion pairs: implementation in the human testicular and adrenal axes. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology (Print), 288(2), R440-R446. [More Information]
  • Handelsman, D., Liu, P. (2005). Andropause: invention, prevention, rejuvenation. Trends in Endocrinology and Metabolism, 16(2), 39-45. [More Information]
  • Liu, P., Christian, R., Ruan, M., Miller, V., Fitzpatrick, L. (2005). Correlating androgen and estrogen steroid receptor expression with coronary calcification and atherosclerosis in men without known coronary artery disease. Journal of Clinical Endocrinology and Metabolism, 90(2), 1041-1046. [More Information]
  • Meier, C., Liu, P., Handelsman, D., Seibel, M. (2005). Endocrine regulation of bone turnover in men. Clinical Endocrinology, 63(6), 603-616. [More Information]
  • Takahashi, P., Liu, P., Roebuck, P., Iranmanesh, A., Veldhuis, J. (2005). Graded inhibition of pulsatile luteinizing hormone secretion by a selective gonadotropin-releasing hormone (GnRH)-receptor antagonist in healthy men: evidence that age attenuates hypothalamic GnRH outflow. Journal of Clinical Endocrinology and Metabolism, 90(5), 2768-2774. [More Information]
  • Liu, P., Pincus, S., Keenan, D., Roelfsema, F., Veldhuis, J. (2005). Joint synchrony of reciprocal hormonal signaling in human paradigms of both ACTH excess and cortisol depletion. American Journal of Physiology: Endocrinology and Metabolism, 289(1), E160-E165. [More Information]
  • Liu, P., Wang, C., Swerdloff, R. (2005). Male sex matters. Clinical Endocrinology, 63(601), 602.
  • Liu, P., Iranmanesh, A., Nehra, A., Keenan, D., Veldhuis, J. (2005). Mechanisms of hypoandrogenemia in healthy aging men. Endocrinology and Metabolism Clinics of North America, 34(4), 935-955. [More Information]
  • Thieben, M., Blacker, D., Liu, P., Harper, C., Wijdicks, E. (2005). Pulmonary function tests and blood gases in worsening myasthenia gravis. Muscle and Nerve, 32(5), 664-7. [More Information]
  • Liu, P., Handelsman, D., Ly, L. (2005). Rates of suppression and recovery of human sperm output in testosterone-based hormonal contraceptive regimens. Human Reproduction, 20(6), 1733-40. [More Information]
  • Liu, P., Swerdloff, R., Wang, C. (2005). Relative testosterone deficiency in older men: clinical definition and presentation. Endocrinology and Metabolism Clinics of North America, 34(4), 957-72, x. [More Information]
  • Yee, B., Liu, P., Phillips, C., Grunstein, R. (2004). Neuroendocrine Changes in Sleep Apnea. Current Opinion in Pulmonary Medicine, 10(6), 475-481.
  • Miller, V., Tindall, D., Liu, P. (2004). Of mice, men and hormones. Arteriosclerosis, Thrombosis, and Vascular Biology, 24, 995-997.
  • Meier, C., Liu, P., Ly, L., De Winter, J., Jimenez, M., Handelsman, D., Seibel, M. (2004). Recombinant Human Chorionic Gonadotropin But Not Dihydrotestosterone Alone Stimulates Osteoblastic Collagen Synthesis In Older Men With Partial Age-Related Androgen Deficiency. Journal of Clinical Endocrinology and Metabolism, 89(6), 3033-3041.
  • Liu, P., Swerdloff, R., Veldhuis, J. (2004). The Rationale, Efficacy and Safety of Androgen Therapy in Older Men: Future Research and Current Practice Recommendations. Journal of Clinical Endocrinology and Metabolism, 89(10), 4789-4796.
  • Liu, P., Heather, A., Handelsman, D. (2003). Androgens and cardiovascular disease. Endocrine Reviews, 24(3), 313-340.
  • Turner, L., Conway, A., Jimenez, M., Liu, P., Forbes, E., McLachlan, R., Handelsman, D. (2003). Contraceptive efficacy of depot progestin and androgen combination in men. Journal of Clinical Endocrinology and Metabolism, 88(10), 4659-4667.
  • Liu, P., Wishart, S., Celermajer, D., Jimenez, M., Di Pierro, I., Conway, A., Handelsman, D. (2003). Do reproductive hormones modify insulin sensitivity and metabolism in older men? A randomised, placebo-controlled clinical trial of recombinant human chorionic gonadotropin. European Journal of Endocrinology, 148(1), 55-56.
  • Crawford, B., Liu, P., Kean, M., Bleasel, J., Handelsman, D. (2003). Randomized placebo-controlled trial of androgen effects on muscle and bone in men requiring long-term systemic glucocorticoid treatment. Journal of Clinical Endocrinology and Metabolism, 88(7), 3167-3176.
  • Liu, P., Handelsman, D. (2003). The present and future state of hormonal treatment for male infertility. Human Reproduction, 9(1), 9-23.
  • Liu, P., Yee, B., Wishart, S., Jimenez, M., Jung, D., Grunstein, R., Handelsman, D. (2003). The short-term effects of high-dose testosterone on sleep, breathing, and function in older men. Journal of Clinical Endocrinology and Metabolism, 88(8), 3605-3613.
  • Liu, P., Wishart, S., Handelsman, D. (2002). A double-blind, placebo-controlled, randomized clinical trial of recombinant human chorionic gonadotropin on muscle strength and physicial function and activity in older men with partial age-related androgen deficiency. Journal of Clinical Endocrinology and Metabolism, 87(7), 3125-3135.
  • Liu, P., Gebski, V., Turner, L., Conway, A., Wishart, S., Handelsman, D. (2002). Predicting pregnancy and spermatogenesis by survival analysis during gonadotrophin treatment of gonadotrophin-deficient infertile men. Human Reproduction, 17(3), 625-633.
  • Ng, M., Liu, P., Williams, A., Nakhla, S., Ly, L., Handelsman, D., Celermajer, D. (2002). Prospective study of effect of androgens on serum inflammatory markers in men. Arteriosclerosis, Thrombosis, and Vascular Biology, 22(7), 1136-1141.
  • Liu, P., Handelsman, D. (2001). Androgens and male ageing. Current Therapeutics: Australia's journal of disease management and drug treatment, 37135, 47-53.
  • Kelleher, S., Liu, P., Turner, L., Handelsman, D., Wishart, S., Di, P., Conway, A. (2001). Long-term outcomes of elective human sperm cryostorage. Human Reproduction, 16, 2632-2639.

Conferences

  • Liu, P., Swerdloff, R., Christenson, P., Handelsman, D., Wang, C. (2007). Factors Influencing Suppression of Spermatogenesis with Male Hormonal Contraceptive Methods. 32nd Annual American Society of Andrology Meeting.
  • Liu, P., Kalak, R., Lue, Y., Erkkilla, K., Simanainen, U., Zhou, H., Hikim, A., Handelsman, D., Seibel, M., Wang, C., Dunstan, C., et al (2007). XXY Mice have an Osteoporotic Phenotype. 29th Annual Meeting American Society for Bone and Mineral Research (ASBMR), Washington DC, USA: American Society for Bone and Mineral Research.
  • Liu, P., Takahashi, P., Roebuck, P., Veldhuis, J. (2006). Age attenuates testosterone's concentration-dependant enhancement of the regularity of luteinizing hormone secretion in healthy men. American endocrine society 88th annual meeting, United States: The Endocrine Society.
  • Lue, Y., Liu, P., Erkkilla, K., Wang, C., Hikim, A., Swerdloff, R. (2006). Fate of bone marrow cells transplanted into the testies. American society of andrology 31st annual meeting, united States: American Society of Andrology.
  • McCrady, S., Liu, P., Lanningham-foster, L., Harris, A., Foster, R., Veldhuis, J., Levine, J. (2006). Fidgeting Movement in adults: impact of age and obesity. The Obesity Society Annual Scientific Meeting, United States: North Amer Assoc Study Obesity.
  • Schwarcz, M., Liu, P., Erkkilla, K., Lue, Y., Abuyounes, D., Jentsch, D., Wang, C., Swerdloff, R. (2006). Gender preference and social behavious of XXY mice. American endocrine society 88th annual meeting, United States: The Endocrine Society.
  • Liu, P., Swerdloff, R., Christenson, P., Wang, C. (2006). Recovery of spermatogenesis after androgen-progestin therapy. Western regional meeting of the American federation of the medical research, United States: The Endocrine Society.
  • Lue, Y., Liu, P., Erkkilla, K., Hikim, A., Wang, C., Swerdloff, R. (2006). Transplanted XY spermatogonia colonise in the seminiferous tubules of XXY mice. American endocrine society 88th annual meeting, United States: The Endocrine Society.
  • Erkkilla, K., Liu, P., Lee, K., Boros, L., Ferrini, M., Hikim, A., Wang, C., Swerdloff, R. (2006). XXY mice exhibit altered palmitate and stearate metabolism in the brain. American endocrine society 88th annual meeting, United States: The Endocrine Society.
  • Liu, P., Keenan, D., Pincus, S., Veldhuis, J. (2004). Analysis of nonlinear pattern synchrony of effector concentration-response secretion pairs: implementation in the young and aging human male gonadal axis.
  • Liu, P., Takahashi, P., Roebuck, P., Nehra, A., Veldhuis, J. (2004). Biological nonuniformity of selective GnRH Receptor-blockade of LH secretory-burst mass at any given antagonist concentration in men.
  • Soares-Welch, C., Mielke, K., Bradford, K., Mahmud, F., Liu, P., Miles, J., Bowers, C., Veldhuis, J. (2004). Heightened responsivity to GHRP-2 and GHRH agonism in the presence of putative somatostatin withdrawal in young women compared with men.
  • Liu, P., Mielke, K., Hoey, K., Veldhuis, J., Khosla, S. (2004). Low dose estradiol rapidly increases osteoblastic procollagen production in postmenopausal women.
  • Liu, P., Roelfsema, F., Keenan, D., Pincus, S., Veldhuis, J. (2004). Pairwise ACTH and cortisol synchrony analyses unveil unequal feedforward-feedback signaling regularity in the older human corticotropic-adrenal axis.
  • Thieben, M., Blacker, D., Liu, P., Harper, C., Wijdicks, E. (2004). The Value of Pulmonary Function Tests in Predicting Intubation in Myasthenic Crises.
  • Meier, C., Liu, P., Ly, L., De Winter, J., Jimenez, M., Handelsman, D., Seibel, M. (2003). Recombinant hCG, but not DHT Stimulates Osteoblastic Collagen Synthesis in Older Men with Partial Age Related Androgen Deficiency.
  • Yee, B., Liu, P., Yang, Q., Wishart, S., Handelsman, D., Grunstein, R. (2002). A double blind, placebo controlled randomised crossover study of intramuscular testosterone esters on sleep in men over 60 years of age.
  • Liu, P., Yee, B., Wishart, S., Yang, Q., Grunstein, R., Handelsman, D. (2002). The acute effects of high dose testosterone on sleep in ageing men.

2013

  • Hoyos, C., Sullivan, D., Liu, P. (2013). Effect of CPAP on the metabolic syndrome: a randomised sham-controlled study. Thorax, 68(6), 588-589. [More Information]
  • Simpson, P., Hoyos, C., Celermajer, D., Liu, P., Ng, M. (2013). Effects of continuous positive airway pressure on endothelial function and circulating progenitor cells in obstructive sleep apnoea: A randomised sham-controlled study. International Journal of Cardiology, 168(3), 2042-2048. [More Information]
  • Killick, R., Wang, D., Hoyos, C., Yee, B., Grunstein, R., Liu, P. (2013). The effects of testosterone on ventilatory responses in men with obstructive sleep apnoea: a randomised, placebo-controlled trial. Journal of Sleep Research, 22(3), 331-336. [More Information]

2012

  • Brillante, R., Laks, L., Cossa, G., Peters, M., Liu, P. (2012). An Overnight Increase in CO(2) Predicts Mortality in Sleep Disordered Breathing. Respirology, 17(6), 933-939. [More Information]
  • Hoyos, C., Yee, B., Phillips, C., Machan, E., Grunstein, R., Liu, P. (2012). Body compositional and cardiometabolic effects of testosterone therapy in obese men with severe obstructive sleep apnea: a randomised placebo-controlled trial. European Journal of Endocrinology, 167(4), 531-541. [More Information]
  • Hoyos, C., Killick, R., Yee, B., Phillips, C., Grunstein, R., Liu, P. (2012). Cardiometabolic changes after continuous positive airway pressure for obstructive sleep apnoea: a randomised sham-controlled study. Thorax, 67(12), 1081-1089. [More Information]
  • Veldhuis, J., Liu, P., Takahashi, P., Keenan, D. (2012). Dynamic testosterone responses to near-physiological LH pulses are determined by the time pattern of prior intravenous LH infusion. American Journal of Physiology: Endocrinology and Metabolism (online), 303(6), e720-e728. [More Information]
  • Sivam, S., Phillips, C., Trenell, M., Yee, B., Liu, P., Wong, K., Grunstein, R. (2012). Effects of 8 weeks of continuous positive airway pressure on abdominal adiposity in obstructive sleep apnoea. The European Respiratory Journal, 40(4), 913-918. [More Information]
  • Hoyos, C., Killick, R., Yee, B., Grunstein, R., Liu, P. (2012). Effects of testosterone therapy on sleep and breathing in obese men with severe obstructive sleep apnoea: a randomized placebo-controlled trial. Clinical Endocrinology, 77(4), 599-607. [More Information]
  • Killick, R., Banks, S., Liu, P. (2012). Implications of Sleep Restriction and Recovery on Metabolic Outcomes. Journal of Clinical Endocrinology and Metabolism, 97(11), 3876-3890. [More Information]
  • Yee, B., Liu, P., Phillips, C., Grunstein, R. (2012). Neuroendocrine Aspects of Sleep Apnea. In Allan I. Pack (Eds.), Sleep Apnea: Pathogenesis, Diagnosis and Treatment, (pp. 286-299). London: Informa Healthcare.
  • Veldhuis, J., Liu, P., Keenan, D., Takahashi, P. (2012). Older men exhibit reduced efficacy of and heightened potency downregulation by intravenous pulses of recombinant human LH: a study in 92 healthy men. American Journal of Physiology: Endocrinology and Metabolism (online), 302(1), E117-E122. [More Information]
  • Brillante, R., Cossa, G., Liu, P., Laks, L. (2012). Rapid eye movement and slow-wave sleep rebound after one night of continuous positive airway pressure for obstructive sleep apnoea. Respirology, 17(3), 547-553. [More Information]

2011

  • Phillips, C., Yee, B., Marshall, N., Liu, P., Sullivan, D., Grunstein, R. (2011). Continuous Positive Airway Pressure Reduces Postprandial Lipidemia in Obstructive Sleep Apnea. A Randomised, Placebo Controlled Crossover Trial. American Journal of Respiratory and Critical Care Medicine, 184(3), 355-361. [More Information]
  • Ilani, N., Liu, P., Swerdloff, R., Wang, C. (2011). Does ethnicity matter in male hormonal contraceptive efficacy? Asian Journal of Andrology, 13(4), 579-584. [More Information]
  • Swerdloff, R., Lue, Y., Liu, P., Erkkila, K., Wang, C. (2011). Mouse model for men with klinefelter syndrome: a multifaceted fit for a complex disorder. Acta Paediatrica: Nurturing the Child, 100(6), 892-899. [More Information]
  • Wang, X., Keenan, D., Pincus, S., Liu, P., Veldhuis, J. (2011). Oscillations in joint synchrony of reproductive hormones in healthy men. American Journal of Physiology: Endocrinology and Metabolism, 301(6), E1163-E1173. [More Information]
  • Marshall, N., Wong, K., Liu, P., Grunstein, R. (2011). Smoking is not better for you than sleep apnea. The Journal of Clinical Sleep Medicine, 7(3), 317-317. [More Information]

2010

  • Veldhuis, J., Takahashi, P., Keenan, D., Liu, P., Mielke, K., Weist, S. (2010). Age disrupts androgen receptor-modulated negative feedback in the gonadal axis in healthy men. American Journal of Physiology: Endocrinology and Metabolism, 299, E675-E682. [More Information]
  • Liu, P., Kalak, R., Lue, Y., Jia, Y., Erkkila, K., Zhou, H., Seibel, M., Wang, C., Swerdloff, R., Dunstan, C. (2010). Genetic and Hormonal Control of Bone Volume, Architecture, and Remodeling in XXY Mice. Journal of Bone and Mineral Research, 25(10), 2148-2154. [More Information]
  • Liu, P., Erkkila, K., Lue, Y., Jentsch, D., Schwarcz, M., Abuyounes, D., Hikim, A., Wang, C., Lee, P., Swerdloff, R. (2010). Genetic, hormonal, and metabolomic influences on social behavior and sex preference of XXY mice. American Journal of Physiology: Endocrinology and Metabolism, 299(3), E446-E455. [More Information]
  • Williams, S., Marshall, N., Kennerson, M., Rogers, N., Liu, P., Grunstein, R. (2010). Modafinil Effects during Acute Continuous Positive Airway Withdrawal: A Randomized Crossover Double-Blind Placebo-controlled Trial. American Journal of Respiratory and Critical Care Medicine, 181(8), 825-831. [More Information]
  • Fennell, C., Sartorius, G., Ly, L., Turner, L., Liu, P., Conway, A., Handelsman, D. (2010). Randomized cross-over clinical trial of injectable vs. implantable depot testosterone for maintenance of testosterone replacement therapy in androgen deficient men. Clinical Endocrinology, 73(1), 102-109. [More Information]
  • Liu, P., Swerdloff, R., Wang, C. (2010). Recent methodological advances in male hormonal contraception. Contraception, 82(5), 471-475. [More Information]
  • Ip, F., di Pierro, I., Brown, R., Cunningham, I., Handelsman, D., Liu, P. (2010). Trough serum testosterone predicts the development of polycythemia in hypogonadal men treated for up to 21 years with subcutaneous testosterone pellets. European Journal of Endocrinology, 162(2), 385-390. [More Information]

2009

  • Kalak, R., Zhou, H., Street, J., Day, R., Modzelewski, J., Spies, C., Liu, P., Li, G., Dunstan, C., Seibel, M. (2009). Endogenous glucocorticoid signaling in osteoblasts is necessary to maintain normal bone structure in mice. Bone, 45(1), 61-67. [More Information]
  • Liu, P., Gordon Baker, H., Jayadev, V., Zacharin, M., Conway, A., Handelsman, D. (2009). Induction of spermatogenesis and fertility during gonadotropin treatment of gonadotropin deficient infertile men: predictors of fertility outcome. Journal of Clinical Endocrinology and Metabolism, 94(3), 801-808. [More Information]
  • Marshall, N., Wong, K., Phillips, C., Liu, P., Knuiman, M., Grunstein, R. (2009). Is sleep apnea an independent risk factor for prevalent and incident diabetes in the Busselton Health Study? The Journal of Clinical Sleep Medicine, 5(1), 15-20. [More Information]
  • Liu, P., Keenan, D., Kok, P., Padmanabhan, V., O'Byrne, K., Veldhuis, J. (2009). Sensitivity and specificity of pulse detection using a new deconvolution method. American Journal of Physiology: Endocrinology and Metabolism, 297(2), E538-E544. [More Information]
  • Veldhuis, J., Keenan, D., Liu, P., Iranmanesh, A., Takahashi, P., Nehra, A. (2009). The aging male hypothalamic-pituitary-gonadal axis: Pulsatility and feedback. Molecular And Cellular Endocrinology, 299(1), 14-22. [More Information]

2008

  • Liu, P., Swerdloff, R., Anawalt, B., Anderson, R., Bremner, W., Elliesen, J., Gu, Y., Kersemaekers, W., McLachlan, R., Meriggiola, M., Handelsman, D., et al (2008). Determinants of the Rate and Extent of Spermatogenic Suppression during Hormonal Male Contraception: An Integrated Analysis. Journal of Clinical Endocrinology and Metabolism, 93(5), 1774-1783. [More Information]
  • Liu, P., McLachlan, R. (2008). Male hormonal contraception: so near and yet so far. Journal of Clinical Endocrinology and Metabolism, 93(7), 2474-2476. [More Information]
  • Marshall, N., Wong, K., Liu, P., Cullen, S., Knuiman, M., Grunstein, R. (2008). Sleep Apnea as an Independent Risk Factor for All-Cause Mortality: The Busselton Health Study. Sleep, 31(8), 1079-1085. [More Information]
  • Grunstein, R., Phillips, C., Liu, P. (2008). Sleep apnea--past, present, future. Sleep Medicine Reviews, 12(1), 1-4. [More Information]

2007

  • Aaltonen, P., Amory, J., Anderson, R., Behre, H., Bialy, G., Blithe, D., Bone, W., Bremner, W., Colvard, D., Handelsman, D., Liu, P., et al (2007). 10th Summit Meeting consensus: recommendations for regulatory approval for hormonal male contraception. Journal Of Andrology, 28(3), 362-363. [More Information]
  • Liu, P., Iranmanesh, A., Keenan, D., Pincus, S., Veldhuis, J. (2007). A Noninvasive Measure of Negative-Feedback Strength, Approximate Entropy, Unmasks Strong Diurnal Variations in the Regularity of Luteinizing Hormone Secretion. American Journal of Physiology: Endocrinology and Metabolism, 293(5), E1409-E1415. [More Information]
  • Liu, P., Beilin, J., Meier, C., Nguyen, T., Center, J., Leedman, P., Seibel, M., Eisman, J., Handelsman, D. (2007). Age-Related Changes in Serum Testosterone and Sex Hormone Binding Globulin in Australian Men: Longitudinal Analyses of Two Geographically Separate Regional Cohorts. Journal of Clinical Endocrinology and Metabolism, 92(9), 3599-3603. [More Information]
  • Liu, P., Caterson, I., Grunstein, R., Handelsman, D. (2007). Androgens, Obesity, and Sleep-Disordered Breathing in Men. Endocrinology and Metabolism Clinics of North America, 36(2), 349-363. [More Information]
  • Yee, B., Buchanan, P., Mahadev, S., Banerjee, D., Liu, P., Phillips, C., Loughnan, G., Steinbeck, K., Grunstein, R. (2007). Assessment of sleep and breathing in adults with Prader-Willi syndrome: a case control series. The Journal of Clinical Sleep Medicine, 3(7), 713-718. [More Information]
  • Chung, T., Kelleher, S., Liu, P., Conway, A., Kritharides, L., Handelsman, D. (2007). Effects of Testosterone and Nandrolone on Cardiac Function: A Randomized, Placebo-Controlled Study. Clinical Endocrinology, 66(2), 235-245. [More Information]
  • Liu, P., Swerdloff, R., Christenson, P., Handelsman, D., Wang, C. (2007). Factors Influencing Suppression of Spermatogenesis with Male Hormonal Contraceptive Methods. 32nd Annual American Society of Andrology Meeting.
  • Lue, Y., Erkkilla, K., Liu, P., Wang, C., Hikim, A., Swerdloff, R. (2007). Fate of bone marrow cells transplanted into the testis. The American Journal of Pathology: cellular and molecular biology of disease, 170(3), 899-908.
  • Liu, P. (2007). Hormonal induction of spermatogenesis in males with hypogonadotropic hypogonadism. In Fouad R. Kandeel (Eds.), Male Reproductive Dysfunction: Pathophysiology and treatment, (pp. 337-348). New York: Informa Healthcare.
  • Liu, P., GOOREN, L., Handelsman, D. (2007). Impact of systemic disease on male sexual function. In Fouad R.Kandeel,Tom F.Lue,Jon L.Pryor,Ronald S.Swerdloff (Eds.), Male Sexual Dysfunction: Pathophysiology and Treatment, (pp. 155-176). New York: Informa Healthcare.
  • Caroll, B., Cassidy, F., Naftolowitz, D., Tatham, N., Wilson, W., Iranmanesh, A., Liu, P., Veldhuis, J. (2007). Pathophysiology of hypercortisolism in depression. Acta Psychiatrica Scandinavica, 115(433), 90-103.
  • Liu, P., Yee, B., Phillips, C., Grunstein, R. (2007). Sleep Apnea and Neuroendocrine Function. Sleep Medicine Clinics, 2(2), 225-236.
  • Liu, P., Kalak, R., Lue, Y., Erkkilla, K., Simanainen, U., Zhou, H., Hikim, A., Handelsman, D., Seibel, M., Wang, C., Dunstan, C., et al (2007). XXY Mice have an Osteoporotic Phenotype. 29th Annual Meeting American Society for Bone and Mineral Research (ASBMR), Washington DC, USA: American Society for Bone and Mineral Research.

2006

  • Liu, P., Takahashi, P., Roebuck, P., Veldhuis, J. (2006). Age attenuates testosterone's concentration-dependant enhancement of the regularity of luteinizing hormone secretion in healthy men. American endocrine society 88th annual meeting, United States: The Endocrine Society.
  • Liu, P., Takahashi, P., Roebuck, P., Veldhuis, J. (2006). Age or factors associated with aging attenuate testosterone's concentration dependant enhancement of the regularity of luteinizing hormone secretion in healthy men. Journal of Clinical Endocrinology and Metabolism, 91(10), 4077-4084. [More Information]
  • Liu, P., Pincus, S., Takahashi, P., Roebuck, P., Iranmanesh, A., Keenan, D., Veldhuis, J. (2006). Aging attenuates both the regularity and joint synchrony of LH and testosterone secretion in normal men: analyses via a model of graded GnRH receptor blockade. American Journal of Physiology: Endocrinology and Metabolism, 290(1), E34-E41. [More Information]
  • Keenan, D., Takahashi, P., Liu, P., Roebuck, P., Nehra, A., Iranmanesh, A., Veldhuis, J. (2006). An ensemble model of the male gonadal axis: illustrative application in aging men. Endocrinology, 147(6), 2817-2828. [More Information]
  • Liu, P., Wang, C., Swerdloff, R. (2006). Does individual responce to androgen replacement therapy affect bone density? Nature clinical practice: Endocrinology and metabolism, , 76-77. [More Information]
  • Liu, P., Handelsman, D. (2006). Early markers in metabolic syndrome in non overweight, middle aged men. Nature Clinical Practice Oncology, 3, 524-525.
  • Liu, P., Handelsman, D. (2006). Early markers of metabolic syndrome in nonoverweight, middle-aged men. Nature Clinical Practice Urology, 3(10), 524-5. [More Information]
  • Handelsman, D., Liu, P. (2006). Editorial: Klinefelter's Syndrome: A Microcosm of Male Reproductive Health. Journal of Clinical Endocrinology and Metabolism, 91(4), 1220-1222.
  • Lue, Y., Liu, P., Erkkilla, K., Wang, C., Hikim, A., Swerdloff, R. (2006). Fate of bone marrow cells transplanted into the testies. American society of andrology 31st annual meeting, united States: American Society of Andrology.
  • McCrady, S., Liu, P., Lanningham-foster, L., Harris, A., Foster, R., Veldhuis, J., Levine, J. (2006). Fidgeting Movement in adults: impact of age and obesity. The Obesity Society Annual Scientific Meeting, United States: North Amer Assoc Study Obesity.
  • Schwarcz, M., Liu, P., Erkkilla, K., Lue, Y., Abuyounes, D., Jentsch, D., Wang, C., Swerdloff, R. (2006). Gender preference and social behavious of XXY mice. American endocrine society 88th annual meeting, United States: The Endocrine Society.
  • Christian, R., Liu, P., Harrington, S., Ruan, M., Miller, V., Fitzpatrick, L. (2006). Intimal Estrogen Receptor (ER)β, but not ERα expression, is correlated with coronary calcification and atherosclerosis in pre- and postmenopausal women. Journal of Clinical Endocrinology and Metabolism, 91(7), 2713-2720. [More Information]
  • Liu, P., Swerdloff, R., Christenson, P., Handelsman, D., Wang, C. (2006). Rate, extent, and modifiers of spermatogenic recovery after hormonal male contraception: an integrated analysis. The Lancet, 367(9520), 1412-1420.
  • Liu, P., Swerdloff, R., Christenson, P., Wang, C. (2006). Recovery of spermatogenesis after androgen-progestin therapy. Western regional meeting of the American federation of the medical research, United States: The Endocrine Society.
  • Seibel, M., Meier, C., Liu, P., Handelsman, D. (2006). Sex steroids and skeletal health in men. In Lane N (Eds.), Osteoporosis and the Osteoporosis of Rheumatic Diseases, (pp. 145-156). Philadelphia: Mosby Elsevier.
  • Lue, Y., Liu, P., Erkkilla, K., Hikim, A., Wang, C., Swerdloff, R. (2006). Transplanted XY spermatogonia colonise in the seminiferous tubules of XXY mice. American endocrine society 88th annual meeting, United States: The Endocrine Society.
  • Erkkilla, K., Liu, P., Lee, K., Boros, L., Ferrini, M., Hikim, A., Wang, C., Swerdloff, R. (2006). XXY mice exhibit altered palmitate and stearate metabolism in the brain. American endocrine society 88th annual meeting, United States: The Endocrine Society.

2005

  • Liu, P., Hoey, K., Mielke, K., Veldhuis, J., Khosla, S. (2005). A randomized placebo-controlled trial of short-term graded transdermal estradiol in healthy gonadotropin-releasing hormone agonist-suppressed pre- and postmenopausal women: effects on serum markers of bone turnover, insulin-like growth factor-I, and osteo. Journal of Clinical Endocrinology and Metabolism, 90(4), 1953-60. [More Information]
  • Liu, P., Takahashi, P., Roebuck, P., Iranmanesh, A., Veldhuis, J. (2005). Age-specific changes in the regulation of LH-dependent testosterone secretion: assessing responsiveness to varying endogenous gonadotropin output in normal men. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology (Print), 289(3), R721-R728. [More Information]
  • Liu, P., Takahashi, P., Roebuck, D., Iranmanesh, A., Veldhuis, J. (2005). Aging in healthy men impairs recombinant human luteinizing hormone (LH)-stimulated testosterone secretion monitored under a two-day intravenous pulsatile LH clamp. Journal of Clinical Endocrinology and Metabolism, 90(10), 5544-5550. [More Information]
  • Liu, P., Pincus, S., Keenan, D., Roelfsema, F., Veldhuis, J. (2005). Analysis of bidirectional pattern synchrony of concentration-secretion pairs: implementation in the human testicular and adrenal axes. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology (Print), 288(2), R440-R446. [More Information]
  • Handelsman, D., Liu, P. (2005). Andropause: invention, prevention, rejuvenation. Trends in Endocrinology and Metabolism, 16(2), 39-45. [More Information]
  • Liu, P., Christian, R., Ruan, M., Miller, V., Fitzpatrick, L. (2005). Correlating androgen and estrogen steroid receptor expression with coronary calcification and atherosclerosis in men without known coronary artery disease. Journal of Clinical Endocrinology and Metabolism, 90(2), 1041-1046. [More Information]
  • Meier, C., Liu, P., Handelsman, D., Seibel, M. (2005). Endocrine regulation of bone turnover in men. Clinical Endocrinology, 63(6), 603-616. [More Information]
  • Takahashi, P., Liu, P., Roebuck, P., Iranmanesh, A., Veldhuis, J. (2005). Graded inhibition of pulsatile luteinizing hormone secretion by a selective gonadotropin-releasing hormone (GnRH)-receptor antagonist in healthy men: evidence that age attenuates hypothalamic GnRH outflow. Journal of Clinical Endocrinology and Metabolism, 90(5), 2768-2774. [More Information]
  • Liu, P., Pincus, S., Keenan, D., Roelfsema, F., Veldhuis, J. (2005). Joint synchrony of reciprocal hormonal signaling in human paradigms of both ACTH excess and cortisol depletion. American Journal of Physiology: Endocrinology and Metabolism, 289(1), E160-E165. [More Information]
  • Liu, P., Wang, C., Swerdloff, R. (2005). Male sex matters. Clinical Endocrinology, 63(601), 602.
  • Liu, P., Iranmanesh, A., Nehra, A., Keenan, D., Veldhuis, J. (2005). Mechanisms of hypoandrogenemia in healthy aging men. Endocrinology and Metabolism Clinics of North America, 34(4), 935-955. [More Information]
  • Thieben, M., Blacker, D., Liu, P., Harper, C., Wijdicks, E. (2005). Pulmonary function tests and blood gases in worsening myasthenia gravis. Muscle and Nerve, 32(5), 664-7. [More Information]
  • Liu, P., Handelsman, D., Ly, L. (2005). Rates of suppression and recovery of human sperm output in testosterone-based hormonal contraceptive regimens. Human Reproduction, 20(6), 1733-40. [More Information]
  • Liu, P., Swerdloff, R., Wang, C. (2005). Relative testosterone deficiency in older men: clinical definition and presentation. Endocrinology and Metabolism Clinics of North America, 34(4), 957-72, x. [More Information]

2004

  • Liu, P., Keenan, D., Pincus, S., Veldhuis, J. (2004). Analysis of nonlinear pattern synchrony of effector concentration-response secretion pairs: implementation in the young and aging human male gonadal axis.
  • Liu, P., Handelsman, D. (2004). Androgen therapy in non-gonadal disease. In Nieschlag E, Behre HM (Eds.), Testosterone: Action, Deficiency and Substitution, (pp. 445-495). United Kingdom: Cambridge University Press.
  • Liu, P., Takahashi, P., Roebuck, P., Nehra, A., Veldhuis, J. (2004). Biological nonuniformity of selective GnRH Receptor-blockade of LH secretory-burst mass at any given antagonist concentration in men.
  • Soares-Welch, C., Mielke, K., Bradford, K., Mahmud, F., Liu, P., Miles, J., Bowers, C., Veldhuis, J. (2004). Heightened responsivity to GHRP-2 and GHRH agonism in the presence of putative somatostatin withdrawal in young women compared with men.
  • Liu, P., Mielke, K., Hoey, K., Veldhuis, J., Khosla, S. (2004). Low dose estradiol rapidly increases osteoblastic procollagen production in postmenopausal women.
  • Liu, P., Takahashi, P., Nehra, A., Pincus, S., Keenan, D., Veldhuis, J. (2004). Neuroendocrine aging: Pituitary-testis: LH/FSH/Prolactin. In George Adelman and Barry H.Smith (Eds.), New Encyclopedia of Neuroscience. Oxford: Elsevier B.V.
  • Yee, B., Liu, P., Phillips, C., Grunstein, R. (2004). Neuroendocrine Changes in Sleep Apnea. Current Opinion in Pulmonary Medicine, 10(6), 475-481.
  • Miller, V., Tindall, D., Liu, P. (2004). Of mice, men and hormones. Arteriosclerosis, Thrombosis, and Vascular Biology, 24, 995-997.
  • Liu, P., Roelfsema, F., Keenan, D., Pincus, S., Veldhuis, J. (2004). Pairwise ACTH and cortisol synchrony analyses unveil unequal feedforward-feedback signaling regularity in the older human corticotropic-adrenal axis.
  • Meier, C., Liu, P., Ly, L., De Winter, J., Jimenez, M., Handelsman, D., Seibel, M. (2004). Recombinant Human Chorionic Gonadotropin But Not Dihydrotestosterone Alone Stimulates Osteoblastic Collagen Synthesis In Older Men With Partial Age-Related Androgen Deficiency. Journal of Clinical Endocrinology and Metabolism, 89(6), 3033-3041.
  • Liu, P., Swerdloff, R., Veldhuis, J. (2004). The Rationale, Efficacy and Safety of Androgen Therapy in Older Men: Future Research and Current Practice Recommendations. Journal of Clinical Endocrinology and Metabolism, 89(10), 4789-4796.
  • Thieben, M., Blacker, D., Liu, P., Harper, C., Wijdicks, E. (2004). The Value of Pulmonary Function Tests in Predicting Intubation in Myasthenic Crises.

2003

  • Liu, P., Heather, A., Handelsman, D. (2003). Androgens and cardiovascular disease. Endocrine Reviews, 24(3), 313-340.
  • Turner, L., Conway, A., Jimenez, M., Liu, P., Forbes, E., McLachlan, R., Handelsman, D. (2003). Contraceptive efficacy of depot progestin and androgen combination in men. Journal of Clinical Endocrinology and Metabolism, 88(10), 4659-4667.
  • Liu, P., Wishart, S., Celermajer, D., Jimenez, M., Di Pierro, I., Conway, A., Handelsman, D. (2003). Do reproductive hormones modify insulin sensitivity and metabolism in older men? A randomised, placebo-controlled clinical trial of recombinant human chorionic gonadotropin. European Journal of Endocrinology, 148(1), 55-56.
  • Liu, P., Handelsman, D. (2003). Hormonal therapy of the infertile man. In Meikle (Eds.), Endocrine Replacement Therapy in Clinical Practice, (pp. 453-467). New Jersey: Humana Press.
  • Liu, P., Handelsman, D. (2003). Hypogonadism In Men With Chronic Renal Failure. In SJ Winters (Eds.), Contemporary Endocrinology: Male Hypogonadism: Basic, Clinical and Therapeutic Principles,, (pp. 225-244). Totowa NJ: Humana Press.
  • Crawford, B., Liu, P., Kean, M., Bleasel, J., Handelsman, D. (2003). Randomized placebo-controlled trial of androgen effects on muscle and bone in men requiring long-term systemic glucocorticoid treatment. Journal of Clinical Endocrinology and Metabolism, 88(7), 3167-3176.
  • Meier, C., Liu, P., Ly, L., De Winter, J., Jimenez, M., Handelsman, D., Seibel, M. (2003). Recombinant hCG, but not DHT Stimulates Osteoblastic Collagen Synthesis in Older Men with Partial Age Related Androgen Deficiency.
  • Liu, P., Handelsman, D. (2003). The present and future state of hormonal treatment for male infertility. Human Reproduction, 9(1), 9-23.
  • Liu, P., Yee, B., Wishart, S., Jimenez, M., Jung, D., Grunstein, R., Handelsman, D. (2003). The short-term effects of high-dose testosterone on sleep, breathing, and function in older men. Journal of Clinical Endocrinology and Metabolism, 88(8), 3605-3613.

2002

  • Yee, B., Liu, P., Yang, Q., Wishart, S., Handelsman, D., Grunstein, R. (2002). A double blind, placebo controlled randomised crossover study of intramuscular testosterone esters on sleep in men over 60 years of age.
  • Liu, P., Wishart, S., Handelsman, D. (2002). A double-blind, placebo-controlled, randomized clinical trial of recombinant human chorionic gonadotropin on muscle strength and physicial function and activity in older men with partial age-related androgen deficiency. Journal of Clinical Endocrinology and Metabolism, 87(7), 3125-3135.
  • Liu, P., Gebski, V., Turner, L., Conway, A., Wishart, S., Handelsman, D. (2002). Predicting pregnancy and spermatogenesis by survival analysis during gonadotrophin treatment of gonadotrophin-deficient infertile men. Human Reproduction, 17(3), 625-633.
  • Ng, M., Liu, P., Williams, A., Nakhla, S., Ly, L., Handelsman, D., Celermajer, D. (2002). Prospective study of effect of androgens on serum inflammatory markers in men. Arteriosclerosis, Thrombosis, and Vascular Biology, 22(7), 1136-1141.
  • Liu, P., Yee, B., Wishart, S., Yang, Q., Grunstein, R., Handelsman, D. (2002). The acute effects of high dose testosterone on sleep in ageing men.

2001

  • Liu, P., Handelsman, D. (2001). Androgens and male ageing. Current Therapeutics: Australia's journal of disease management and drug treatment, 37135, 47-53.
  • Kelleher, S., Liu, P., Turner, L., Handelsman, D., Wishart, S., Di, P., Conway, A. (2001). Long-term outcomes of elective human sperm cryostorage. Human Reproduction, 16, 2632-2639.
  • Liu, P., Handelsman, D. (2001). Research Summaries Book.

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