Associate Professor Peter Middleton

Clinical Associate Professor
Sleep Medicine, Westmead Clinical School

Telephone +61 2 9845 6797
Fax +61 2 9845 7286

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Selected grants

2007

  • Determining the cellular mechanisms involved in the airway response to topical citrate; Middleton P, Cook D; National Health and Medical Research Council (NHMRC)/Project Grants.

Selected publications

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Book Chapters

  • Middleton, S., Middleton, P. (2008). Assessment and investigation of patient's problems. In Jennifer A. Pryor, S Ammani Prasad (Eds.), Physiotherapy for Respiratory and Cardiac Problems: Adults and Paediatrics, (pp. 1-20). United Kingdom: Churchill Livingstone.
  • Middleton, P., Alton, E. (2006). In vivo measurement of airway potential difference to assess CFTR function in man. In Bush A; Alton E; Davies J; Griesenbach U; Jaffe A (Eds.), Cystic Fibrosis in the 21st Century, (pp. 102-108). Basel: S. Karger AG.

Journals

  • Naehrlich, L., Ballmann, M., Davies, J., Derichs, N., Gonska, T., Hjelte, L., Van Konigsbruggen-Rietschel, S., Leal, T., Melotti, P., Middleton, P., et al (2014). Nasal potential difference measurements in diagnosis of cystic fibrosis: An international survey. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 13(1), 24-28. [More Information]
  • De Boeck, K., Kent, L., Davies, J., Derichs, N., Amaral, M., Rowe, S., Middleton, P., de Jonge, H., Bronsveld, I., Wilschanski, M., et al (2013). CFTR biomarkers: time for promotion to surrogate end-point. The European Respiratory Journal, 41(1), 203-216. [More Information]
  • Middleton, P., Chen, S., Meyer, W. (2013). Fungal infections and treatment in cystic fibrosis. Current Opinion in Pulmonary Medicine, 19(6), 670-675. [More Information]
  • Bronsveld, I., Vermeulen, F., Sands, D., Leal, T., Leonard, A., Melotti, P., Yaakov, Y., Nooijer, R., De Boeck, K., Sermet, I., Middleton, P., et al (2013). Influence of perfusate temperature on nasal potential difference. The European Respiratory Journal, 42(2), 389-393. [More Information]
  • Harun, A., Blyth, C., Gilgado, F., Middleton, P., Chen, S., Meyer, W. (2011). Development and Validation of a Multiplex PCR for Detection of Scedosporium spp. in Respiratory Tract Specimens from Patients with Cystic Fibrosis. Journal of Clinical Microbiology, 49(4), 1508-1512. [More Information]
  • De Boeck, K., Derichs, N., Fajac, I., de Jonge, H., Bronsveld, I., Sermet, I., Vermeulen, F., Sheppard, D., Cuppens, H., Hug, M., Middleton, P., et al (2011). New clinical diagnostic procedures for cystic fibrosis in Europe. Journal of Cystic Fibrosis, 10(Issue SUPPL. 2), S53-S66. [More Information]
  • Bishop, J., Erskine, O., Middleton, P. (2011). Timing of dornase alpha inhalation does not affect the efficacy of an airway clearance regimen in adults with cystic fibrosis: a randomised crossover trial. Journal of Physiotherapy, 57(4), 223-229. [More Information]
  • Blyth, C., Middleton, P., Harun, A., Sorrell, T., Meyer, W., Chen, S. (2010). Clinical associations and prevalence of Scedosporium spp. in Australian cystic fibrosis patients: identification of novel risk factors? Medical Mycology, 48(1), S37-S44. [More Information]
  • Blyth, C., Harun, A., Middleton, P., Sleiman, S., Lee, O., Sorrell, T., Meyer, W., Chen, S. (2010). Detection of Occult Scedosporium Species in Respiratory Tract Specimens from Patients with Cystic Fibrosis by Use of Selective Media. Journal of Clinical Microbiology, 48(1), 314-316. [More Information]
  • Middleton, P., House, H. (2010). Measurement of airway ion transport assists the diagnosis of cystic fibrosis. Pediatric Pulmonology, 45(8), 789-795. [More Information]
  • De Boeck, K., Derichs, N., Fajac, I., de Jonge, H., Bronsveld, I., Sermet, I., Vermeulen, F., Sheppard, D., Cuppens, H., Middleton, P., et al (2010). New clinical diagnostic procedures for cystic fibrosis in Europe. Journal of Cystic Fibrosis, 9(S3), S44-S57.
  • George, A., Jones, P., Middleton, P. (2009). Cystic fibrosis infections: treatment strategies and prospects. FEMS Microbiology Letters, 300(2), 153-164. [More Information]
  • House, H., Middleton, P. (2009). Impact of different chloride and glucose solutions on nasal potential difference. Pediatric Pulmonology, 44(7), 645-648. [More Information]
  • Gobau, C., Wilschanski, M., Skalicka, V., Lebecque, P., Southern, K., Sermet, I., Munck, A., Derichs, N., Middleton, P., Hjelte, L., et al (2009). Phenotypic characterisation of patients with intermediate sweat chloride values: towards validation of the European diagnostic algorithm for cystic fibrosis. Thorax, 64(8), 683-691. [More Information]
  • Vandemheen, K., O'Connor, A., Bell, S., Freitag, A., Bye, P., Jeanneret, A., Berthiaume, Y., Brown, N., Wilcox, P., Middleton, P. (2009). Randomized Trial of a Decision Aid for Patients with Cystic Fibrosis Considering Lung Transplantation. American Journal of Respiratory and Critical Care Medicine, 180(8), 761-768. [More Information]
  • Middleton, S., Vermeulen, W., Byth Wilson, K., Sullivan, C., Middleton, P. (2009). Treatment of obstructive sleep apnoea in Samoa progressively reduces daytime blood pressure over 6 months. Respirology, 14(3), 404-410. [More Information]
  • Treerat, P., Widmer, A., Middleton, P., Iredell, J., George, A. (2008). In vitro interactions of tobramycin with various nonantibiotics against Pseudomonas aeruginosa and Burkholderia cenocepacia. FEMS Microbiology Letters, 285(12), 40-50. [More Information]
  • Middleton, P. (2008). Management of patients with COPD: a comparison of the INSPIRE and TORCH studies. American Journal of Respiratory and Critical Care Medicine, 178(1), 106; author reply 106-7. [More Information]
  • Middleton, P. (2007). Editorial overview: Clinical utility of synergy testing for multidrug resistant Pseudomonas aeruginosa isolated from patients with cystic fibrosis. Paediatric Respiratory Reviews, 8(3), 262-264. [More Information]
  • Middleton, P., Kidd, T., Williams, B. (2005). Combination aerosol therapy to treat Burkholderia cepacia complex. European Respiratory Journal, 26(2), 305-308. [More Information]
  • Middleton, P., Pollard, K., Donohoo, E., Wheatley, J., Geddes, D., Alton, E. (2003). Airway surface liquid calcium modulates chloride permeability in the cystic fibrosis airway. American Journal of Respiratory and Critical Care Medicine, 168(10), 1223-1226.
  • Edwards, N., Middleton, P., Blyton, D., Sullivan, C. (2002). Sleep Disordered Breathing and Pregnancy. Thorax, 57(6), 555-558.

2014

  • Naehrlich, L., Ballmann, M., Davies, J., Derichs, N., Gonska, T., Hjelte, L., Van Konigsbruggen-Rietschel, S., Leal, T., Melotti, P., Middleton, P., et al (2014). Nasal potential difference measurements in diagnosis of cystic fibrosis: An international survey. Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 13(1), 24-28. [More Information]

2013

  • De Boeck, K., Kent, L., Davies, J., Derichs, N., Amaral, M., Rowe, S., Middleton, P., de Jonge, H., Bronsveld, I., Wilschanski, M., et al (2013). CFTR biomarkers: time for promotion to surrogate end-point. The European Respiratory Journal, 41(1), 203-216. [More Information]
  • Middleton, P., Chen, S., Meyer, W. (2013). Fungal infections and treatment in cystic fibrosis. Current Opinion in Pulmonary Medicine, 19(6), 670-675. [More Information]
  • Bronsveld, I., Vermeulen, F., Sands, D., Leal, T., Leonard, A., Melotti, P., Yaakov, Y., Nooijer, R., De Boeck, K., Sermet, I., Middleton, P., et al (2013). Influence of perfusate temperature on nasal potential difference. The European Respiratory Journal, 42(2), 389-393. [More Information]

2011

  • Harun, A., Blyth, C., Gilgado, F., Middleton, P., Chen, S., Meyer, W. (2011). Development and Validation of a Multiplex PCR for Detection of Scedosporium spp. in Respiratory Tract Specimens from Patients with Cystic Fibrosis. Journal of Clinical Microbiology, 49(4), 1508-1512. [More Information]
  • De Boeck, K., Derichs, N., Fajac, I., de Jonge, H., Bronsveld, I., Sermet, I., Vermeulen, F., Sheppard, D., Cuppens, H., Hug, M., Middleton, P., et al (2011). New clinical diagnostic procedures for cystic fibrosis in Europe. Journal of Cystic Fibrosis, 10(Issue SUPPL. 2), S53-S66. [More Information]
  • Bishop, J., Erskine, O., Middleton, P. (2011). Timing of dornase alpha inhalation does not affect the efficacy of an airway clearance regimen in adults with cystic fibrosis: a randomised crossover trial. Journal of Physiotherapy, 57(4), 223-229. [More Information]

2010

  • Blyth, C., Middleton, P., Harun, A., Sorrell, T., Meyer, W., Chen, S. (2010). Clinical associations and prevalence of Scedosporium spp. in Australian cystic fibrosis patients: identification of novel risk factors? Medical Mycology, 48(1), S37-S44. [More Information]
  • Blyth, C., Harun, A., Middleton, P., Sleiman, S., Lee, O., Sorrell, T., Meyer, W., Chen, S. (2010). Detection of Occult Scedosporium Species in Respiratory Tract Specimens from Patients with Cystic Fibrosis by Use of Selective Media. Journal of Clinical Microbiology, 48(1), 314-316. [More Information]
  • Middleton, P., House, H. (2010). Measurement of airway ion transport assists the diagnosis of cystic fibrosis. Pediatric Pulmonology, 45(8), 789-795. [More Information]
  • De Boeck, K., Derichs, N., Fajac, I., de Jonge, H., Bronsveld, I., Sermet, I., Vermeulen, F., Sheppard, D., Cuppens, H., Middleton, P., et al (2010). New clinical diagnostic procedures for cystic fibrosis in Europe. Journal of Cystic Fibrosis, 9(S3), S44-S57.

2009

  • George, A., Jones, P., Middleton, P. (2009). Cystic fibrosis infections: treatment strategies and prospects. FEMS Microbiology Letters, 300(2), 153-164. [More Information]
  • House, H., Middleton, P. (2009). Impact of different chloride and glucose solutions on nasal potential difference. Pediatric Pulmonology, 44(7), 645-648. [More Information]
  • Gobau, C., Wilschanski, M., Skalicka, V., Lebecque, P., Southern, K., Sermet, I., Munck, A., Derichs, N., Middleton, P., Hjelte, L., et al (2009). Phenotypic characterisation of patients with intermediate sweat chloride values: towards validation of the European diagnostic algorithm for cystic fibrosis. Thorax, 64(8), 683-691. [More Information]
  • Vandemheen, K., O'Connor, A., Bell, S., Freitag, A., Bye, P., Jeanneret, A., Berthiaume, Y., Brown, N., Wilcox, P., Middleton, P. (2009). Randomized Trial of a Decision Aid for Patients with Cystic Fibrosis Considering Lung Transplantation. American Journal of Respiratory and Critical Care Medicine, 180(8), 761-768. [More Information]
  • Middleton, S., Vermeulen, W., Byth Wilson, K., Sullivan, C., Middleton, P. (2009). Treatment of obstructive sleep apnoea in Samoa progressively reduces daytime blood pressure over 6 months. Respirology, 14(3), 404-410. [More Information]

2008

  • Middleton, S., Middleton, P. (2008). Assessment and investigation of patient's problems. In Jennifer A. Pryor, S Ammani Prasad (Eds.), Physiotherapy for Respiratory and Cardiac Problems: Adults and Paediatrics, (pp. 1-20). United Kingdom: Churchill Livingstone.
  • Treerat, P., Widmer, A., Middleton, P., Iredell, J., George, A. (2008). In vitro interactions of tobramycin with various nonantibiotics against Pseudomonas aeruginosa and Burkholderia cenocepacia. FEMS Microbiology Letters, 285(12), 40-50. [More Information]
  • Middleton, P. (2008). Management of patients with COPD: a comparison of the INSPIRE and TORCH studies. American Journal of Respiratory and Critical Care Medicine, 178(1), 106; author reply 106-7. [More Information]

2007

  • Middleton, P. (2007). Editorial overview: Clinical utility of synergy testing for multidrug resistant Pseudomonas aeruginosa isolated from patients with cystic fibrosis. Paediatric Respiratory Reviews, 8(3), 262-264. [More Information]

2006

  • Middleton, P., Alton, E. (2006). In vivo measurement of airway potential difference to assess CFTR function in man. In Bush A; Alton E; Davies J; Griesenbach U; Jaffe A (Eds.), Cystic Fibrosis in the 21st Century, (pp. 102-108). Basel: S. Karger AG.

2005

  • Middleton, P., Kidd, T., Williams, B. (2005). Combination aerosol therapy to treat Burkholderia cepacia complex. European Respiratory Journal, 26(2), 305-308. [More Information]

2003

  • Middleton, P., Pollard, K., Donohoo, E., Wheatley, J., Geddes, D., Alton, E. (2003). Airway surface liquid calcium modulates chloride permeability in the cystic fibrosis airway. American Journal of Respiratory and Critical Care Medicine, 168(10), 1223-1226.

2002

  • Edwards, N., Middleton, P., Blyton, D., Sullivan, C. (2002). Sleep Disordered Breathing and Pregnancy. Thorax, 57(6), 555-558.

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