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Dr Philip Morgan

Research Fellow
Medicine, Central Clinical School
Heart Research Institute

Telephone +61 2 8208 8900

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Selected grants

2013

  • Protein modification by gamma irradiation in the presence of oxygen: characterising oxidation products to understand the mechanisms leading to damage; Morgan P; Australian Institute of Nuclear Science and Engineering (AINSE)/Awards.
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Selected publications

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Journals

  • Nedoboy, P., Morgan, P., Mocatta, T., Richards, M., Winterbourn, C., Davies, M. (2014). High plasma thiocyanate levels are associated with enhanced myeloperoxidase-induced thiol oxidation and long-term survival in subjects following a first myocardial infarction. Free Radical Research, 48(10), 1256-1266. [More Information]
  • Morgan, P., Sheahan, P., Davies, M. (2014). Perturbation of Human Coronary Artery Endothelial Cell Redox State and NADPH Generation by Methylglyoxal. PloS One, 9(1), e86564. [More Information]
  • Lau, E., Morgan, P., Belousova, E., Toelle, B., Ayer, J., Celermajer, D., Marks, G. (2013). Asymmetric dimethylarginine and asthma: results from the Childhood Asthma Prevention Study. The European Respiratory Journal, 41(5), 1234-1237. [More Information]
  • Morgan, P., Sheahan, P., Pattison, D., Davies, M. (2013). Methylglyoxal-induced modification of arginine residues decreases the activity of NADPH-generating enzymes. Free Radical Biology and Medicine, 61, 229-242. [More Information]
  • de Bock, M., Derraik, J., Brennan, C., Biggs, J., Morgan, P., Hodgkinson, S., Hofman, P., Cutfield, W. (2013). Olive (Olea europaea L.) Leaf Polyphenols Improve Insulin Sensitivity in Middle-Aged Overweight Men: A Randomized, Placebo-Controlled, Crossover Trial. PloS One, 8(3), e57622. [More Information]
  • Thallas-Bonke, V., Coughlan, M., Tan, A., Harcourt, B., Morgan, P., Davies, M., Forbes, J., Bach, L., Cooper, M. (2013). Targeting the AGE-RAGE axis improves renal function in the context of a healthy diet low in advanced glycation end-product content. Nephrology, 18(1), 47-56. [More Information]
  • Morgan, P., Pattison, D., Davies, M. (2012). Quantification of hydroxyl radical-derived oxidation products in peptides containing glycine, alanine, valine, and proline. Free Radical Biology and Medicine, 52(2), 328-339. [More Information]
  • Skaff, O., Pattison, D., Morgan, P., Bachana, R., Jain, V., Priyadarsini, I., Davies, M. (2012). Selenium-containing amino acids are targets for myeloperoxidase-derived hypothiocyanous acid: determination of absolute rate constants and implications for biological damage. The Biochemical Journal, 441(1), 305-316. [More Information]
  • Gracanin, M., Lam, M., Morgan, P., Rodgers, K., Hawkins, C., Davies, M. (2011). Amino acid, peptide, and protein hydroperoxides and their decomposition products modify the activity of the 26S proteasome. Free Radical Biology and Medicine, 50(2), 389-399. [More Information]
  • Morgan, P., Pattison, D., Talib, J., Summers, F., Harmer, J., Celermajer, D., Hawkins, C., Davies, M. (2011). High plasma thiocyanate levels in smokers are a key determinant of thiol oxidation induced by myeloperoxidase. Free Radical Biology and Medicine, 51(9), 1815-1822. [More Information]
  • Suryo Rahmanto, A., Morgan, P., Hawkins, C., Davies, M. (2010). Cellular effects of peptide and protein hydroperoxides. Free Radical Biology and Medicine, 48(8), 1071-1078. [More Information]
  • Rahmanto, A., Morgan, P., Hawkins, C., Davies, M. (2010). Cellular effects of photo-generated oxidants and long-lived, reactive, hydroperoxide photoproducts. Free Radical Biology and Medicine, 49(10), 1505-1515. [More Information]
  • Moheimani, F., Morgan, P., van Reyk, D., Davies, M. (2010). Deleterious effects of reactive aldehydes and glycated proteins on macrophage proteasomal function: Possible links between diabetes and atherosclerosis. Biochimica et Biophysica Acta-Molecular Basis of Disease, 1802 (6), 561-571. [More Information]
  • Sourris, K., Harcourt, B., Penfold, S., Yap, F., Morley, A., Morgan, P., Davies, M., Baker, S., Jerums, G., Forbes, J. (2010). Modulation of the Cellular Expression of Circulating Advanced Glycation End-Product Receptors in Type 2 Diabetic Nephropathy. Experimental Diabetes Research, 210(974681), 1-9. [More Information]
  • Peskin, A., Cox, A., Nagy, P., Morgan, P., Hampton, M., Davies, M., Winterbourn, C. (2010). Removal of amino acid, peptide and protein hydroperoxides by reaction with peroxiredoxins 2 and 3. Biochemical Journal, 432(2), 313-321. [More Information]
  • Morgan, P., Sturgess, A., Hennessy, A., Davies, M. (2007). Serum protein oxidation and apolipoprotein CIII levels in people with systemic lupus erythematosus with and without nephritis. Free Radical Research, 41(12), 1301-1312. [More Information]
  • Morgan, P., Sturgess, A., Davies, M. (2005). Increased Levels of Serum Protein Oxidation and Correlation With Disease Activity in Systemic Lupus Erythematosus. Arthritis and Rheumatism, 52(7), 2069-2079. [More Information]
  • Morgan, P., Dean, R., Davies, M. (2004). Protective Mechanisms Against Peptide And Protein Peroxides Generated By Singlet Oxygen. Free Radical Biology and Medicine, 36(4), 484-496. [More Information]

2014

  • Nedoboy, P., Morgan, P., Mocatta, T., Richards, M., Winterbourn, C., Davies, M. (2014). High plasma thiocyanate levels are associated with enhanced myeloperoxidase-induced thiol oxidation and long-term survival in subjects following a first myocardial infarction. Free Radical Research, 48(10), 1256-1266. [More Information]
  • Morgan, P., Sheahan, P., Davies, M. (2014). Perturbation of Human Coronary Artery Endothelial Cell Redox State and NADPH Generation by Methylglyoxal. PloS One, 9(1), e86564. [More Information]

2013

  • Lau, E., Morgan, P., Belousova, E., Toelle, B., Ayer, J., Celermajer, D., Marks, G. (2013). Asymmetric dimethylarginine and asthma: results from the Childhood Asthma Prevention Study. The European Respiratory Journal, 41(5), 1234-1237. [More Information]
  • Morgan, P., Sheahan, P., Pattison, D., Davies, M. (2013). Methylglyoxal-induced modification of arginine residues decreases the activity of NADPH-generating enzymes. Free Radical Biology and Medicine, 61, 229-242. [More Information]
  • de Bock, M., Derraik, J., Brennan, C., Biggs, J., Morgan, P., Hodgkinson, S., Hofman, P., Cutfield, W. (2013). Olive (Olea europaea L.) Leaf Polyphenols Improve Insulin Sensitivity in Middle-Aged Overweight Men: A Randomized, Placebo-Controlled, Crossover Trial. PloS One, 8(3), e57622. [More Information]
  • Thallas-Bonke, V., Coughlan, M., Tan, A., Harcourt, B., Morgan, P., Davies, M., Forbes, J., Bach, L., Cooper, M. (2013). Targeting the AGE-RAGE axis improves renal function in the context of a healthy diet low in advanced glycation end-product content. Nephrology, 18(1), 47-56. [More Information]

2012

  • Morgan, P., Pattison, D., Davies, M. (2012). Quantification of hydroxyl radical-derived oxidation products in peptides containing glycine, alanine, valine, and proline. Free Radical Biology and Medicine, 52(2), 328-339. [More Information]
  • Skaff, O., Pattison, D., Morgan, P., Bachana, R., Jain, V., Priyadarsini, I., Davies, M. (2012). Selenium-containing amino acids are targets for myeloperoxidase-derived hypothiocyanous acid: determination of absolute rate constants and implications for biological damage. The Biochemical Journal, 441(1), 305-316. [More Information]

2011

  • Gracanin, M., Lam, M., Morgan, P., Rodgers, K., Hawkins, C., Davies, M. (2011). Amino acid, peptide, and protein hydroperoxides and their decomposition products modify the activity of the 26S proteasome. Free Radical Biology and Medicine, 50(2), 389-399. [More Information]
  • Morgan, P., Pattison, D., Talib, J., Summers, F., Harmer, J., Celermajer, D., Hawkins, C., Davies, M. (2011). High plasma thiocyanate levels in smokers are a key determinant of thiol oxidation induced by myeloperoxidase. Free Radical Biology and Medicine, 51(9), 1815-1822. [More Information]

2010

  • Suryo Rahmanto, A., Morgan, P., Hawkins, C., Davies, M. (2010). Cellular effects of peptide and protein hydroperoxides. Free Radical Biology and Medicine, 48(8), 1071-1078. [More Information]
  • Rahmanto, A., Morgan, P., Hawkins, C., Davies, M. (2010). Cellular effects of photo-generated oxidants and long-lived, reactive, hydroperoxide photoproducts. Free Radical Biology and Medicine, 49(10), 1505-1515. [More Information]
  • Moheimani, F., Morgan, P., van Reyk, D., Davies, M. (2010). Deleterious effects of reactive aldehydes and glycated proteins on macrophage proteasomal function: Possible links between diabetes and atherosclerosis. Biochimica et Biophysica Acta-Molecular Basis of Disease, 1802 (6), 561-571. [More Information]
  • Sourris, K., Harcourt, B., Penfold, S., Yap, F., Morley, A., Morgan, P., Davies, M., Baker, S., Jerums, G., Forbes, J. (2010). Modulation of the Cellular Expression of Circulating Advanced Glycation End-Product Receptors in Type 2 Diabetic Nephropathy. Experimental Diabetes Research, 210(974681), 1-9. [More Information]
  • Peskin, A., Cox, A., Nagy, P., Morgan, P., Hampton, M., Davies, M., Winterbourn, C. (2010). Removal of amino acid, peptide and protein hydroperoxides by reaction with peroxiredoxins 2 and 3. Biochemical Journal, 432(2), 313-321. [More Information]

2007

  • Morgan, P., Sturgess, A., Hennessy, A., Davies, M. (2007). Serum protein oxidation and apolipoprotein CIII levels in people with systemic lupus erythematosus with and without nephritis. Free Radical Research, 41(12), 1301-1312. [More Information]

2005

  • Morgan, P., Sturgess, A., Davies, M. (2005). Increased Levels of Serum Protein Oxidation and Correlation With Disease Activity in Systemic Lupus Erythematosus. Arthritis and Rheumatism, 52(7), 2069-2079. [More Information]

2004

  • Morgan, P., Dean, R., Davies, M. (2004). Protective Mechanisms Against Peptide And Protein Peroxides Generated By Singlet Oxygen. Free Radical Biology and Medicine, 36(4), 484-496. [More Information]
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