Professor Philip Poronnik

Professor of Biomedical Sciences (Educational Strategy)
Biomedical Sciences, School of Medical Sciences


Map

Selected grants

2014

  • CLARIOstar Multifunctional Microplate Reader for Shared Used at the Open Access, Multi-User Molecular Biology Core Facility; Huang M, Scolyer R, Fraser S, Sahni S, Speranza T, Owens T, Barrs V, Ju Y, Kovacevic Z, Lu Z, Camp A, Slobedman B, Morris B, Oliver B, Dos Remedios C, Kalinowski D, Fu D, Lai D, Lovicu F, Allbutt H, Triccas J, Burgess J, Kril J, Dixon K, Rendina L, Byrne M, King N, Groundwater P, Williamson P, Ho J, Dong Q, Bao B, Assinder S, McLennan S, Richardson D, Ammit A, Sharland A, Hardikar A, Hong A, Hambly B, Lee C, Murphy C, Goldsbury C, Johnstone D, Lane D, Hibbs D, Joshua D, Huq F, Halliday G, Sutherland G, Zreiqat H, Lok H, Lyons G, Jansson P, Black J, Zhu L, Sunde M, Day M, Naylor M, Buckland M, Murray M, Shafie N, Lay P, Poronnik P, Codd R, Mason R, Ryan R, Christopherson R, de Graaf S; National Health and Medical Research Council (NHMRC)/Equipment Grants.

2013

  • The transportome: a coordinate complex regulating brain excitation and inhibition; Pow D, Lee A, Poronnik P, Balcar V; National Health and Medical Research Council (NHMRC)/Project Grants.

2012

  • Understanding the mechanistic basis of microalbuminuria in diabetic nephropathy; Poronnik P, Tesch G; National Health and Medical Research Council (NHMRC)/Project Grants.
  • A central role for carbonic anhydrase in renal hypertrophy and interstitial fibrosis; Poronnik P, Casey J; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Scholarship, leadership and advocacy: Quality learning and teaching in Australian universities; Poronnik P; Australian Learning and Teaching Council (ALTC)/Strategic Leadership Grant.

2011

  • Collaborative Universities Biomedical Education Network; Poronnik P; Australian Learning and Teaching Council (ALTC)/Discipline Networks Grant.

2009

  • Albuminuria in diabetic nephropathy: redefining the paradigm; Tesch G, Poronnik P; National Health and Medical Research Council (NHMRC)/Project Grants.
  • A central role for carbonic anhydrase in the pathogenesis of diabetic nephropathy; Poronnik P, Casey u; National Health and Medical Research Council (NHMRC)/Project Grants.
  • A novel marker of distressed neurons in the hypoxic brain: Regulation, Junction and potential clinical utility; Poronnik P, Colditz ?, Pow D; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Implementation of Social Network Analysis to monitor the development of student networking capacity; Poronnik P; Australian Learning and Teaching Council (ALTC)/Competitive Grants Programme.

2008

  • Facility for analysing behaviour, learning and motor skills in animal models; Sah P, Bartlett P, McGrath J, Poronnik P, Markovich D, Mackay-Sim A.
  • Assessing the physiological roles of ubiquitination in regulating neuronal ion channels, receptors and transporters; Kumar R, Poronnik P; ARC/Discovery Grant.

2002

  • Molecular basis of G protein receptor-effector coupling in epithelial cells; Cook D, Poronnik P; Australian Research Council (ARC)/Discovery Projects (DP).
  • Novel strategies for the early identification, prevention and treatment of the microvascular complications of diabetes; Gilbert R, Pollock C, Poronnik P; National Health and Medical Research Council (NHMRC)/Program Grants.

2001

  • Molecular mechanisms linking proteinuria and sodium retention; Poronnik P, Pollock C; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Not known; Poronnik P; DVC Research/Bridging Support Grant.

2000

  • Altered intracellular signalling in response to hyperglycaemia reflects an inherent predisposition to nephropathy; Pollock C, Poronnik P; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Sanyo-86C ultra-low freezer for sample storage; Poronnik P; National Health and Medical Research Council (NHMRC)/Equipment Grants.
  • The role of hyperglycaemia in the regulation of human proximal tubular growth and sodium-hydrogen exchange activity by insulin-like growth; Pollock C, Poronnik P; Juvenile Diabetes Foundation International/Diabetes Research Grants.

1999

  • Nikon fluorescence microscope for visualisation of GEP expressing adenoviruses and fusion proteins; Poronnik P, Cook D; Clive & Vera Ramaciotti Foundation/Research Grants.

Selected publications

Download citations: PDF RTF Endnote

Journals

  • Slattery, C., Lee, A., Zhang, Y., Kelly, D., Nikolic-Paterson, D., Tesch, G., Poronnik, P. (2014). In vivo visualization of albumin degradation in the proximal tubule. Kidney International, 74(11), 1480-1486. [More Information]
  • Huang, C., Day, M., Poronnik, P., Pollock, C., Chen, X. (2014). Inhibition of KCa3.1 suppresses TGF-Beta1 induced MCP-1 expression in human proximal tubular cells through Smad3, p38 and ERK1/2 signaling pathways. The International Journal of Biochemistry and Cell Biology, 47(1), 1-10. [More Information]
  • Ekberg, J., Boase, N., Rychkov, G., Manning, J., Poronnik, P., Kumar, S. (2014). Nedd4-2 (NEDD4L) controls intracellular Na+ -mediated activity of voltage-gated sodium channels in primary cortical neurons. Biochemical Journal, 457(1), 27-31. [More Information]
  • Briffa, J., Grinfeld, E., McAinch, A., Poronnik, P., Hryciw, D. (2014). Short term exposure to elevated levels of leptin reduces proximal tubule cell metabolic activity. Molecular And Cellular Endocrinology, 382(1), 38-45. [More Information]
  • Camera, D., Boase, N., Kumar, S., Pow, D., Poronnik, P. (2014). Subtle gait abnormalities in Nedd4 heterozygous mice. Behavioural Brain Research, 260, 15-24. [More Information]
  • Briffa, J., McAinch, A., Poronnik, P., Hryciw, D. (2013). Adipokines as a link between obesity and chronic kidney disease. American Journal of Physiology: Renal Physiology (Print), 305(12), F1629-F1636. [More Information]
  • Jenkin, K., McAinch, A., Briffa, J., Zhang, Y., Kelly, D., Pollock, C., Poronnik, P., Hryciw, D. (2013). Cannabinoid Receptor 2 Expression in Human Proximal Tubule Cells is Regulated by Albumin Independent of ERK1/2 Signaling. Cellular Physiology and Biochemistry, 32(5), 1309-1319. [More Information]
  • Donovan, P., Poronnik, P. (2013). Nedd4 and Nedd4-2: Ubiquitin ligases at work in the neuron. The International Journal of Biochemistry and Cell Biology, 45(3), 706-710. [More Information]
  • Kruger, W., Monteith, G., Poronnik, P. (2013). NHERF-1 regulation of EGF and neurotensin signalling in HT-29 epithelial cells. Biochemical and Biophysical Research Communications, 432(4), 568-573. [More Information]
  • Slattery, C., Jang, Y., Kruger, W., Hryciw, D., Lee, A., Poronnik, P. (2013). γ-Secretase inhibition promotes fibrotic effects of albumin in proximal tubular epithelial cells. British Journal of Pharmacology, 169(6), 1239-1251. [More Information]
  • Lee, A., Anderson, A., Beasley, S., Barnett, N., Poronnik, P., Pow, D. (2012). A new splice variant of the glutamate-aspartate transporter: Cloning and immunolocalization of GLAST1c in rat, pig and human brains. Journal of Chemical Neuroanatomy, 43(1), 52-63. [More Information]
  • Lee, A., Anderson, A., Rayfeild, A., Stevens, M., Poronnik, P., Meabon, J., Cook, D., Pow, D. (2012). Localisation of novel forms of glutamate transporters and the cystine-glutamate antiporter in the choroid plexus: Implications for CSF glutamate homeostasis. Journal of Chemical Neuroanatomy, 43(1), 64-75. [More Information]
  • Hryciw, D., Kruger, W., Briffa, J., Slattery, C., Bolithon, A., Lee, A., Poronnik, P. (2012). Sgk-1 is a positive regulator of constitutive albumin uptake in renal proximal tubule cells. Cellular Physiology and Biochemistry, 30(5), 1215-1226. [More Information]
  • Hryciw, D., Jenkin, K., Simcocks, A., Grinfeld, E., McAinch, A., Poronnik, P. (2012). The interaction between megalin and ClC-5 is scaffolded by the Na +-H + exchanger regulatory factor 2 (NHERF2) in proximal tubule cells. The International Journal of Biochemistry and Cell Biology, 44(5), 815-823. [More Information]
  • Slattery, C., Jenkin, K., Lee, A., Simcocks, A., McAinch, A., Poronnik, P., Hryciw, D. (2011). Na +-H + exchanger regulatory factor 1 (NHERF1) PDZ scaffold binds an internal binding site in the scavenger receptor megalin. Cellular Physiology and Biochemistry, 27(2), 171-178. [More Information]
  • Hu, H., O'Mullane, L., Cummins, M., Campbell, C., Hosoda, Y., Poronnik, P., Dinudom, A., Cook, D. (2010). Negative regulation of Ca2+ influx during P2Y2 purinergic receptor activation is mediated by Gβγ-subunits. Cell Calcium, 47(1), 55-64. [More Information]
  • Lee, A., Lingwood, B., Bjorkman, T., Miller, S., Poronnik, P., Barnett, N., Colditz, P., Pow, D. (2010). Rapid loss of glutamine synthetase from astrocytes in response to hypoxia: Implications for excitotoxicity. Journal of Chemical Neuroanatomy, 39(3), 211-220. [More Information]
  • Kruger, W., Yun, C., Monteith, G., Poronnik, P. (2009). Muscarinic-induced recruitment of plasma membrane Ca 2+-ATPase involves PSD-95/Dlg/Zo-1-mediated interactions. The Journal of Biological Chemistry, 284(3), 1820-1830. [More Information]
  • Schuetz, F., Kumar, S., Poronnik, P., Adams, D. (2008). Regulation of the voltage-gated K+ channels KCNQ2/3 and KCNQ3/5 by serum- and glucocorticoid-regulated kinase-1. American Journal of Physiology: Cell Physiology, 295(1), C73-C80. [More Information]
  • Stevens, V., Saad, S., Poronnik, P., Fenton Lee, C., Polhill, T., Pollock, C. (2008). The role of SGK-1 in angiotensin II-mediated sodium reabsorption in human proximal tubular cells. Nephrology, Dialysis, Transplantation, 23(6), 1834-1843. [More Information]
  • He, Y., Hryciw, D., Carroll, M., Myers, S., Whitbread, A., Kumar, S., Poronnik, P., Hooper, J. (2008). The ubiquitin-protein ligase Nedd4-2 differentially interacts with and regulates members of the tweety family of chloride ion channels. The Journal of Biological Chemistry, 283(35), 24000-24010. [More Information]
  • Pollock, C., Poronnik, P. (2007). Albumin transport and processing by the proximal tubule: physiology and pathophysiology. Current Opinion In Nephrology And Hypertension, 16(4), 359-364. [More Information]
  • Qi, W., Chen, X., Poronnik, P., Pollock, C. (2007). Transforming growth factor-beta/connective tissue growth factor axis in the kidney. The International Journal of Biochemistry and Cell Biology, 40(1 available online 20 Jan 2007), 9-13. [More Information]
  • Hryciw, D., Ekberg, J., Ferguson, C., Lee, A., Wang, D., Parton, R., Pollock, C., Yun, C., Poronnik, P. (2006). Regulation of albumin endocytosis by PSD95/Dlg/ZO-1 (PDZ) scaffolds - Interaction of Na+-H+ exchange regulatory factor-2 with ClC-5. Journal of Biological Chemistry, 281(23), 16068-16077.
  • Qi, W., Chen, X., Poronnik, P., Pollock, C. (2006). The renal cortical fibroblast in renal tubulointerstitial fibrosis. The International Journal of Biochemistry and Cell Biology, 38(1), 1-5. [More Information]
  • Hryciw, D., Ekberg, J., Pollock, C., Poronnik, P. (2005). ClC-5: A chloride channel with multiple roles in renal tubular albumin uptake. The International Journal of Biochemistry and Cell Biology, 38(7), 1036-1042. [More Information]
  • Saad, S., Stevens, V., Wassef, L., Poronnik, P., Kelly, D., Gilbert, R., Pollock, C. (2005). High glucose transactivates the EGF receptor and up-regulates serum glucocorticoid kinase in the proximal tubule. Kidney International, 68(3), 985-997. [More Information]
  • Qi, W., Twigg, S., Chen, X., Polhill, T., Poronnik, P., Gilbert, R., Pollock, C. (2005). Integrated actions of transforming growth factor-beta(1) and connective tissue growth factor in renal fibrosis. American Journal of Physiology: Renal Physiology (Print), 288(4), F800-F809.
  • Zafiriou, S., Stanners, S., Saad, S., Polhill, T., Poronnik, P., Pollock, C. (2005). Pioglitazone Inhibits Cell Growth and Reduces Matrix Production in Human Kidney Fibroblasts. Journal of the American Society of Nephrology, 16(3), 638-645. [More Information]
  • Hryciw, D., Pollock, C., Poronnik, P. (2005). PKC-α-mediated remodeling of the actin cytoskeleton is involved in constitutive albumin uptake by proximal tubule cells. American Journal of Physiology: Renal Physiology (Print), 288(6), F1227-F1235. [More Information]
  • McGinn, C., Poronnik, P., Gallery, E., Pollock, C. (2004). A Method For The Isolation Of Glomerular And Tubulointerstitial Endothelial Cells. Comparison Of Characteristics With human umbilical vein endothelial cell model. Nephrology, 9(4), 229-237.
  • Field, M., Jackson, C., Pollock, C., Poronnik, P., Young, B., Qi, W. (2004). Human Cortical Fibroblast Responses To High Glucose And Hypoxia. Nephron Journals, Nephron Physiology: Volume 96(4), 121-129.
  • Hryciw, D., Lee, E., Pollock, C., Poronnik, P. (2004). Molecular Changes In Proximal Tubule Function In Diabetes Mellitus. Clinical and Experimental Pharmacology and Physiology, 31(5-6), 372-379.
  • Hryciw, D., Ekberg, J., Lee, A., Lensink, I., Kumar, S., Guggino, W., Cook, D., Pollock, C., Poronnik, P. (2004). Nedd4-2 Functionally Interacts With Clc-5: Involvement In Constitutive Albumin Endocytosis In Proximal Tubule Cells. Journal of Biological Chemistry, 279(53), 54996-55007.
  • Zafiriou, S., Stanners, S., Polhill, T., Poronnik, P., Pollock, C. (2004). Pioglitazone Increases Renal Tubular Cell Albumin Uptake But Limits Proinflammatory And Fibrotic Responses. Kidney International, 65(5), 1647-1653.
  • Carpenter, L., Mitchell, C., Xu, Z., Poronnik, P., Both, G., Biden, T. (2004). Pkc Alpha Is Activated But Not Required During Glucose-Induced Insulin Secretion From Rat Pancreatic Islets. Diabetes, 53(1), 53-60.
  • Fotia, A., Ekberg, J., Adams, D., Cook, D., Poronnik, P., Kumar, S. (2004). Regulation Of Neuronal Voltage-Gated Sodium Channels By The Ubiquitin-Protein Ligases Nedd4 And Nedd4-2. Journal of Biological Chemistry, 279(28), 28930-28935.
  • Polhill, T., Saad, S., Poronnik, P., Fulcher, G., Pollock, C. (2004). Short-Term Peaks In Glucose Promote Renal Fibrogenesis Independently Of Total Glucose Exposure. American Journal of Physiology: Renal Physiology (Print), 287(2), F268-F273.
  • McGinn, C., Poronnik, P., Gallery, E., Pollock, C. (2004). The Effects Of High Glucose And Atorvastatin On Endothelial Cell Matrix Production. Diabetic Medicine, 21(10), 1102-1107.
  • Drumm, K., Lee, E., Stanners, S., Gassner, B., Gekle, M., Poronnik, P., Pollock, C. (2003). Albumin and Glucose effects on Cell Growth Parameters, Albumin Uptake and Na+/Ha-Exchanger Isoform 3 in OK Cells. Cellular Physiology and Biochemistry, 13(4), 199-206.
  • Hryciw, D., Wang, Y., Devuyst, O., Pollock, C., Poronnik, P., Guggino, W. (2003). Cofilin Interacts with ClC-5 and Regulates Albumin Uptake in Proximal Tubule Cell Lines. Journal of Biological Chemistry, 278(41), 40169-40176.
  • Lee, E., Pollock, C., Drumm, K., Barden, J., Poronnik, P. (2003). Effects of pathophysiological concentrations of albumin on NHE3 activity and cell proliferation in primary cultures of human proximal tubule cells. American Journal of Physiology: Renal Physiology (Print), 258(4), F748-F757.
  • McGinn, C., Saad, S., Poronnik, P., Pollock, C. (2003). High glucose-mediated effects on endothelial cell proliferation occur via p38 MAP kinase. American Journal of Physiology: Endocrinology and Metabolism, 285, E708-E717.
  • Weinhaus, A., TABIIN, M., Poronnik, P., PALMA, C., Cook, D., Tuch, B. (2003). Insulin secretagogues, but not glucose, stimulate an increase in (Ca2+)i in the fetal human and porcine Beta-cell. Journal of Clinical Endocrinology and Metabolism, 88(6), 2753-2759.
  • Cummins, M., O'Mullane, L., Barden, J., Cook, D., Poronnik, P. (2002). Antisense co-suppression of Galphaq & Galpha11 demonstrates that both isoforms mediate M3-receptor-activated Ca2+ signalling in intact epithelial cells. Pfluegers Archiv: European journal of physiology, 444(5), 644-653. [More Information]
  • Chambers, L., Black, J., Poronnik, P., Johnson, P. (2001). Functional effects of protease-activated receptor-2 stimulation on human airway smooth muscle. American Journal of Physiology: Lung Cellular and Molecular Physiology, 281.

Conferences

  • Hryciw, D., Ekberg, J., Lee, A., Lensink, I., Kumar, S., Guggino, W., Cook, D., Pollock, C., Poronnik, P. (2012). Nedd4-2 is required for constitutive albumin endocytosis in proximal tubule cells. 35th International Congress of Physiological Sciences, United States: Federation of American Societies for Experimental Biology.
  • Ekberg, J., Fotia, A., Adams, D., Cook, D., Kumar, S., Poronnik, P. (2005). Sglk-1 and Nedd4/4-2 regulation of voltage-sensitive sodium channels. 35th International Congress of Physiological Sciences, United States: Federation of American Societies for Experimental Biology.

2014

  • Slattery, C., Lee, A., Zhang, Y., Kelly, D., Nikolic-Paterson, D., Tesch, G., Poronnik, P. (2014). In vivo visualization of albumin degradation in the proximal tubule. Kidney International, 74(11), 1480-1486. [More Information]
  • Huang, C., Day, M., Poronnik, P., Pollock, C., Chen, X. (2014). Inhibition of KCa3.1 suppresses TGF-Beta1 induced MCP-1 expression in human proximal tubular cells through Smad3, p38 and ERK1/2 signaling pathways. The International Journal of Biochemistry and Cell Biology, 47(1), 1-10. [More Information]
  • Ekberg, J., Boase, N., Rychkov, G., Manning, J., Poronnik, P., Kumar, S. (2014). Nedd4-2 (NEDD4L) controls intracellular Na+ -mediated activity of voltage-gated sodium channels in primary cortical neurons. Biochemical Journal, 457(1), 27-31. [More Information]
  • Briffa, J., Grinfeld, E., McAinch, A., Poronnik, P., Hryciw, D. (2014). Short term exposure to elevated levels of leptin reduces proximal tubule cell metabolic activity. Molecular And Cellular Endocrinology, 382(1), 38-45. [More Information]
  • Camera, D., Boase, N., Kumar, S., Pow, D., Poronnik, P. (2014). Subtle gait abnormalities in Nedd4 heterozygous mice. Behavioural Brain Research, 260, 15-24. [More Information]

2013

  • Briffa, J., McAinch, A., Poronnik, P., Hryciw, D. (2013). Adipokines as a link between obesity and chronic kidney disease. American Journal of Physiology: Renal Physiology (Print), 305(12), F1629-F1636. [More Information]
  • Jenkin, K., McAinch, A., Briffa, J., Zhang, Y., Kelly, D., Pollock, C., Poronnik, P., Hryciw, D. (2013). Cannabinoid Receptor 2 Expression in Human Proximal Tubule Cells is Regulated by Albumin Independent of ERK1/2 Signaling. Cellular Physiology and Biochemistry, 32(5), 1309-1319. [More Information]
  • Donovan, P., Poronnik, P. (2013). Nedd4 and Nedd4-2: Ubiquitin ligases at work in the neuron. The International Journal of Biochemistry and Cell Biology, 45(3), 706-710. [More Information]
  • Kruger, W., Monteith, G., Poronnik, P. (2013). NHERF-1 regulation of EGF and neurotensin signalling in HT-29 epithelial cells. Biochemical and Biophysical Research Communications, 432(4), 568-573. [More Information]
  • Slattery, C., Jang, Y., Kruger, W., Hryciw, D., Lee, A., Poronnik, P. (2013). γ-Secretase inhibition promotes fibrotic effects of albumin in proximal tubular epithelial cells. British Journal of Pharmacology, 169(6), 1239-1251. [More Information]

2012

  • Lee, A., Anderson, A., Beasley, S., Barnett, N., Poronnik, P., Pow, D. (2012). A new splice variant of the glutamate-aspartate transporter: Cloning and immunolocalization of GLAST1c in rat, pig and human brains. Journal of Chemical Neuroanatomy, 43(1), 52-63. [More Information]
  • Lee, A., Anderson, A., Rayfeild, A., Stevens, M., Poronnik, P., Meabon, J., Cook, D., Pow, D. (2012). Localisation of novel forms of glutamate transporters and the cystine-glutamate antiporter in the choroid plexus: Implications for CSF glutamate homeostasis. Journal of Chemical Neuroanatomy, 43(1), 64-75. [More Information]
  • Hryciw, D., Ekberg, J., Lee, A., Lensink, I., Kumar, S., Guggino, W., Cook, D., Pollock, C., Poronnik, P. (2012). Nedd4-2 is required for constitutive albumin endocytosis in proximal tubule cells. 35th International Congress of Physiological Sciences, United States: Federation of American Societies for Experimental Biology.
  • Hryciw, D., Kruger, W., Briffa, J., Slattery, C., Bolithon, A., Lee, A., Poronnik, P. (2012). Sgk-1 is a positive regulator of constitutive albumin uptake in renal proximal tubule cells. Cellular Physiology and Biochemistry, 30(5), 1215-1226. [More Information]
  • Hryciw, D., Jenkin, K., Simcocks, A., Grinfeld, E., McAinch, A., Poronnik, P. (2012). The interaction between megalin and ClC-5 is scaffolded by the Na +-H + exchanger regulatory factor 2 (NHERF2) in proximal tubule cells. The International Journal of Biochemistry and Cell Biology, 44(5), 815-823. [More Information]

2011

  • Slattery, C., Jenkin, K., Lee, A., Simcocks, A., McAinch, A., Poronnik, P., Hryciw, D. (2011). Na +-H + exchanger regulatory factor 1 (NHERF1) PDZ scaffold binds an internal binding site in the scavenger receptor megalin. Cellular Physiology and Biochemistry, 27(2), 171-178. [More Information]

2010

  • Hu, H., O'Mullane, L., Cummins, M., Campbell, C., Hosoda, Y., Poronnik, P., Dinudom, A., Cook, D. (2010). Negative regulation of Ca2+ influx during P2Y2 purinergic receptor activation is mediated by Gβγ-subunits. Cell Calcium, 47(1), 55-64. [More Information]
  • Lee, A., Lingwood, B., Bjorkman, T., Miller, S., Poronnik, P., Barnett, N., Colditz, P., Pow, D. (2010). Rapid loss of glutamine synthetase from astrocytes in response to hypoxia: Implications for excitotoxicity. Journal of Chemical Neuroanatomy, 39(3), 211-220. [More Information]

2009

  • Kruger, W., Yun, C., Monteith, G., Poronnik, P. (2009). Muscarinic-induced recruitment of plasma membrane Ca 2+-ATPase involves PSD-95/Dlg/Zo-1-mediated interactions. The Journal of Biological Chemistry, 284(3), 1820-1830. [More Information]

2008

  • Schuetz, F., Kumar, S., Poronnik, P., Adams, D. (2008). Regulation of the voltage-gated K+ channels KCNQ2/3 and KCNQ3/5 by serum- and glucocorticoid-regulated kinase-1. American Journal of Physiology: Cell Physiology, 295(1), C73-C80. [More Information]
  • Stevens, V., Saad, S., Poronnik, P., Fenton Lee, C., Polhill, T., Pollock, C. (2008). The role of SGK-1 in angiotensin II-mediated sodium reabsorption in human proximal tubular cells. Nephrology, Dialysis, Transplantation, 23(6), 1834-1843. [More Information]
  • He, Y., Hryciw, D., Carroll, M., Myers, S., Whitbread, A., Kumar, S., Poronnik, P., Hooper, J. (2008). The ubiquitin-protein ligase Nedd4-2 differentially interacts with and regulates members of the tweety family of chloride ion channels. The Journal of Biological Chemistry, 283(35), 24000-24010. [More Information]

2007

  • Pollock, C., Poronnik, P. (2007). Albumin transport and processing by the proximal tubule: physiology and pathophysiology. Current Opinion In Nephrology And Hypertension, 16(4), 359-364. [More Information]
  • Qi, W., Chen, X., Poronnik, P., Pollock, C. (2007). Transforming growth factor-beta/connective tissue growth factor axis in the kidney. The International Journal of Biochemistry and Cell Biology, 40(1 available online 20 Jan 2007), 9-13. [More Information]

2006

  • Hryciw, D., Ekberg, J., Ferguson, C., Lee, A., Wang, D., Parton, R., Pollock, C., Yun, C., Poronnik, P. (2006). Regulation of albumin endocytosis by PSD95/Dlg/ZO-1 (PDZ) scaffolds - Interaction of Na+-H+ exchange regulatory factor-2 with ClC-5. Journal of Biological Chemistry, 281(23), 16068-16077.
  • Qi, W., Chen, X., Poronnik, P., Pollock, C. (2006). The renal cortical fibroblast in renal tubulointerstitial fibrosis. The International Journal of Biochemistry and Cell Biology, 38(1), 1-5. [More Information]

2005

  • Hryciw, D., Ekberg, J., Pollock, C., Poronnik, P. (2005). ClC-5: A chloride channel with multiple roles in renal tubular albumin uptake. The International Journal of Biochemistry and Cell Biology, 38(7), 1036-1042. [More Information]
  • Saad, S., Stevens, V., Wassef, L., Poronnik, P., Kelly, D., Gilbert, R., Pollock, C. (2005). High glucose transactivates the EGF receptor and up-regulates serum glucocorticoid kinase in the proximal tubule. Kidney International, 68(3), 985-997. [More Information]
  • Qi, W., Twigg, S., Chen, X., Polhill, T., Poronnik, P., Gilbert, R., Pollock, C. (2005). Integrated actions of transforming growth factor-beta(1) and connective tissue growth factor in renal fibrosis. American Journal of Physiology: Renal Physiology (Print), 288(4), F800-F809.
  • Zafiriou, S., Stanners, S., Saad, S., Polhill, T., Poronnik, P., Pollock, C. (2005). Pioglitazone Inhibits Cell Growth and Reduces Matrix Production in Human Kidney Fibroblasts. Journal of the American Society of Nephrology, 16(3), 638-645. [More Information]
  • Hryciw, D., Pollock, C., Poronnik, P. (2005). PKC-α-mediated remodeling of the actin cytoskeleton is involved in constitutive albumin uptake by proximal tubule cells. American Journal of Physiology: Renal Physiology (Print), 288(6), F1227-F1235. [More Information]
  • Ekberg, J., Fotia, A., Adams, D., Cook, D., Kumar, S., Poronnik, P. (2005). Sglk-1 and Nedd4/4-2 regulation of voltage-sensitive sodium channels. 35th International Congress of Physiological Sciences, United States: Federation of American Societies for Experimental Biology.

2004

  • McGinn, C., Poronnik, P., Gallery, E., Pollock, C. (2004). A Method For The Isolation Of Glomerular And Tubulointerstitial Endothelial Cells. Comparison Of Characteristics With human umbilical vein endothelial cell model. Nephrology, 9(4), 229-237.
  • Field, M., Jackson, C., Pollock, C., Poronnik, P., Young, B., Qi, W. (2004). Human Cortical Fibroblast Responses To High Glucose And Hypoxia. Nephron Journals, Nephron Physiology: Volume 96(4), 121-129.
  • Hryciw, D., Lee, E., Pollock, C., Poronnik, P. (2004). Molecular Changes In Proximal Tubule Function In Diabetes Mellitus. Clinical and Experimental Pharmacology and Physiology, 31(5-6), 372-379.
  • Hryciw, D., Ekberg, J., Lee, A., Lensink, I., Kumar, S., Guggino, W., Cook, D., Pollock, C., Poronnik, P. (2004). Nedd4-2 Functionally Interacts With Clc-5: Involvement In Constitutive Albumin Endocytosis In Proximal Tubule Cells. Journal of Biological Chemistry, 279(53), 54996-55007.
  • Zafiriou, S., Stanners, S., Polhill, T., Poronnik, P., Pollock, C. (2004). Pioglitazone Increases Renal Tubular Cell Albumin Uptake But Limits Proinflammatory And Fibrotic Responses. Kidney International, 65(5), 1647-1653.
  • Carpenter, L., Mitchell, C., Xu, Z., Poronnik, P., Both, G., Biden, T. (2004). Pkc Alpha Is Activated But Not Required During Glucose-Induced Insulin Secretion From Rat Pancreatic Islets. Diabetes, 53(1), 53-60.
  • Fotia, A., Ekberg, J., Adams, D., Cook, D., Poronnik, P., Kumar, S. (2004). Regulation Of Neuronal Voltage-Gated Sodium Channels By The Ubiquitin-Protein Ligases Nedd4 And Nedd4-2. Journal of Biological Chemistry, 279(28), 28930-28935.
  • Polhill, T., Saad, S., Poronnik, P., Fulcher, G., Pollock, C. (2004). Short-Term Peaks In Glucose Promote Renal Fibrogenesis Independently Of Total Glucose Exposure. American Journal of Physiology: Renal Physiology (Print), 287(2), F268-F273.
  • McGinn, C., Poronnik, P., Gallery, E., Pollock, C. (2004). The Effects Of High Glucose And Atorvastatin On Endothelial Cell Matrix Production. Diabetic Medicine, 21(10), 1102-1107.

2003

  • Drumm, K., Lee, E., Stanners, S., Gassner, B., Gekle, M., Poronnik, P., Pollock, C. (2003). Albumin and Glucose effects on Cell Growth Parameters, Albumin Uptake and Na+/Ha-Exchanger Isoform 3 in OK Cells. Cellular Physiology and Biochemistry, 13(4), 199-206.
  • Hryciw, D., Wang, Y., Devuyst, O., Pollock, C., Poronnik, P., Guggino, W. (2003). Cofilin Interacts with ClC-5 and Regulates Albumin Uptake in Proximal Tubule Cell Lines. Journal of Biological Chemistry, 278(41), 40169-40176.
  • Lee, E., Pollock, C., Drumm, K., Barden, J., Poronnik, P. (2003). Effects of pathophysiological concentrations of albumin on NHE3 activity and cell proliferation in primary cultures of human proximal tubule cells. American Journal of Physiology: Renal Physiology (Print), 258(4), F748-F757.
  • McGinn, C., Saad, S., Poronnik, P., Pollock, C. (2003). High glucose-mediated effects on endothelial cell proliferation occur via p38 MAP kinase. American Journal of Physiology: Endocrinology and Metabolism, 285, E708-E717.
  • Weinhaus, A., TABIIN, M., Poronnik, P., PALMA, C., Cook, D., Tuch, B. (2003). Insulin secretagogues, but not glucose, stimulate an increase in (Ca2+)i in the fetal human and porcine Beta-cell. Journal of Clinical Endocrinology and Metabolism, 88(6), 2753-2759.

2002

  • Cummins, M., O'Mullane, L., Barden, J., Cook, D., Poronnik, P. (2002). Antisense co-suppression of Galphaq & Galpha11 demonstrates that both isoforms mediate M3-receptor-activated Ca2+ signalling in intact epithelial cells. Pfluegers Archiv: European journal of physiology, 444(5), 644-653. [More Information]

2001

  • Chambers, L., Black, J., Poronnik, P., Johnson, P. (2001). Functional effects of protease-activated receptor-2 stimulation on human airway smooth muscle. American Journal of Physiology: Lung Cellular and Molecular Physiology, 281.

To update your profile click here. For support on your academic profile contact .