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Dr Radhika Seimon

Research Fellow
Boden Institute of Obesity, Nutrition, Exercise &
Eating Disorders
Faculty of Medicine and Health
The University of Sydney

Member of the Charles Perkins Centre

Telephone +61 2 8627 1918
Fax +61 2 8627 0141

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Biographical details

Dr Radhika Seimon is passionate about finding more effective dietary approaches for the prevention and management of human obesity that minimise appetite, promote favourable changes in body composition and optimise weight loss.

Dr Seimon completed her PhD in 2012 at the University of Adelaide, where her research focused on the interrelated, oral and gastrointestinal mechanisms regulating appetite and energy intake in humans. Immediately after completion she moved to the University of Sydney's Boden Institute of Obesity, Nutrition, Exercise & Eating Disorders.

Her current research lies in obesity physiology and is focused on the effects on appetite and body composition of severe versus moderate dietary energy restriction. It is of utmost clinical significance given the importance of maintaining optimum body composition for reducing the risk of diabetes, heart disease, frailty and osteoporosis, and given the increasing use of severe energy restriction for the clinical management of obesity.

In 2014, she was awarded a NHMRC Peter Doherty – Australian Biomedical Fellowship (Postdoctoral) (2014-2017). Furthermore, in the same year she won the Endocrine Society of Australia Postdoctoral Award and was the recipient of the Australia New Zealand Obesity Society Young Investigator Award.

Radhika Seimon (PhD, University of Adelaide 2012), NHMRC Early Career Research Fellow (2014-2017)

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Current research students

Project title Research student
How reliable are body composition monitoring scales? Hamish FERNANDO
Exploring Accredited Practising Dietitians and client perceptions of different weight loss methods: A grounded theory study. Claudia HARPER
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Selected grants

2018

  • Bridging Support Fellowship - Seimon; Seimon R; DVC Research/Bridging Support Fellowship.

2017

  • Improving weight loss by intermittent use of very low energy diet: the TANGO diet trial (Temporary phases of accelerated weight loss for noticeably greater outcomes); Salis (nee Sainsbury) A, Byrne N, Markovic T, Seimon R; National Health and Medical Research Council (NHMRC)/Project Grants.

2014

  • Long-term effects of severe versus moderate energy restriction on adiposity, lean body mass, muscle strength and bone density in obese adults; Seimon R; National Health and Medical Research Council (NHMRC)/Early Career Fellowships.
  • Effects of fast versus slow weight loss on fat, muscle and bone in postmenopausal women; Seimon R; Endocrine Society of Australia/Postdoctoral Award.

2009

  • Top-up Scholarship; Seimon R; Centre of Research Excellence in Translating Nutritional Science to Good Health/Research Grant.
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Selected publications

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Journals

  • Seimon, R., Wild-Taylor, A., Gibson, A., Harper, C., McClintock, S., Fernando, H., Hsu, M., Quinto da Luz, F., Keating, S., Johnson, N., Grieve, S., Markovic, T., Caterson, I., Sainsbury, A., et al (2018). Less waste on waist measurements: Determination of optimal waist circumference measurement site to predict visceral adipose tissue in postmenopausal women with obesity. Nutrients, 10(2:239). [More Information]
  • Seimon, R., Gibson, A., Harper, C., Keating, S., Johnson, N., Quinto da Luz, F., Fernando, H., Skilton, M., Markovic, T., Caterson, I., Salis (nee Sainsbury), A., et al (2018). Rationale and Protocol for a Randomized Controlled Trial Comparing Fast versus Slow Weight Loss in Postmenopausal Women with Obesity-The TEMPO Diet Trial. Healthcare, 6(3), 1-28. [More Information]
  • Hsu, M., Harper, C., Gibson, A., Sweeting, A., McBride, J., Markovic, T., Caterson, I., Byrne, N., Salis (nee Sainsbury), A., Seimon, R. (2018). Recruitment Strategies for a Randomised Controlled Trial Comparing Fast Versus Slow Weight Loss in Postmenopausal Women with Obesity-The TEMPO Diet Trial. Healthcare, 6(3), 1-17. [More Information]
  • Alharbi, T., Wong, J., Markovic, T., Yue, D., Wu, T., Brooks, B., Hetherington, J., Seimon, R., Gibson, A., Toth, K., Silveira, S., Salis (nee Sainsbury), A., Little, T. (2017). Brief report: Ramadan as a model of intermittent fasting: Effects on body composition, metabolic parameters, gut hormones and appetite in adults with and without type 2 diabetes mellitus. Obesity Medicine, 6, 15-17. [More Information]
  • Maggioni, A., Caterson, I., Urso, R., Coutinho, W., Finer, N., Van Gaal, L., Legler, U., Sharma, A., Seimon, R., Sweeting, A., et al (2017). Relation between weight loss and causes of death in patients with cardiovascular disease: Finding from the SCOUT trial. Journal of Cardiovascular Medicine (Hagerstown), 18(3), 144-151. [More Information]
  • Gibson, A., Hsu, M., Rangan, A., Seimon, R., Lee, C., Das, A., Finch, C., Salis (nee Sainsbury), A. (2016). Accuracy of hands v. household measures as portion size estimation aids. Journal of Nutritional Science, 5, 1-11. [More Information]
  • Schober, G., Lange, K., Steinert, R., Hutchison, A., Luscombe-Marsh, N., Landrock, M., Horowitz, M., Seimon, R., Feinle-Bisset, C. (2016). Contributions of upper gut hormones and motility to the energy intake-suppressant effects of intraduodenal nutrients in healthy, lean men - a pooled-data analysis. Physiological Reports, 4(17), 1-14. [More Information]
  • Zibellini, J., Seimon, R., Lee, C., Gibson, A., Hsu, M., Salis (nee Sainsbury), A. (2016). Effect of diet-induced weight loss on muscle strength in adults with overweight or obesity - a systematic review and meta-analysis of clinical trials. Obesity Reviews, 17(8), 647-663. [More Information]
  • Harper, C., Pattinson, A., Fernando, H., Zibellini, J., Seimon, R., Salis (nee Sainsbury), A. (2016). Effects of obesity treatments on bone mineral density, bone turnover and fracture risk in adults with overweight or obesity. Hormone Molecular Biology and Clinical Investigation, 28(3), 133-149. [More Information]
  • Gibson, A., Seimon, R., Franklin, J., Markovic, T., Byrne, N., Manson, E., Caterson, I., Salis (nee Sainsbury), A. (2016). Fast versus slow weight loss: development process and rationale behind the dietary interventions for the TEMPO Diet Trial. Obesity Science & Practice, 2(2), 162-173. [More Information]
  • Seimon, R., Shi, Y., Slack, K., Lee, K., Fernando, H., Nguyen, A., Zhang, L., Lin, S., Enriquez, R., Lau, J., Salis (nee Sainsbury), A., et al (2016). Intermittent Moderate Energy Restriction Improves Weight Loss Efficiency in Diet-Induced Obese Mice. PloS One, 11(1), 1-20. [More Information]
  • Seimon, R., Espinoza, D., Finer, N., James, W., Legler, U., Coutinho, W., Sharma, A., Van Gaal, L., Maggioni, A., Sweeting, A., Gebski, V., Caterson, I., et al (2015). Changes in body weight and pulse: outcome events in overweight and obese subjects with cardiovascular disease in the SCOUT trial. International Journal of Obesity, 39(5), 849-857. [More Information]
  • Seimon, R., Roekenes, J., Zibellini, J., Zhu, B., Gibson, A., Hills, A., Wood, R., King, N., Byrne, N., Salis (nee Sainsbury), A. (2015). Do intermittent diets provide physiological benefits over continuous diets for weight loss? A systematic review of clinical trials. Molecular And Cellular Endocrinology, 418, 153-172. [More Information]
  • Gibson, A., Seimon, R., Lee, C., Ayre, J., Franklin, J., Markovic, T., Caterson, I., Salis (nee Sainsbury), A. (2015). Do ketogenic diets really suppress appetite? A systematic review and meta-analysis. Obesity Reviews, 16(1), 64-76. [More Information]
  • Zibellini, J., Seimon, R., Lee, C., Gibson, A., Hsu, M., Shapses, S., Nguyen, T., Sainsbury, A. (2015). Does Diet-Induced Weight Loss Lead to Bone Loss in Overweight or Obese Adults? A Systematic Review and Meta-Analysis of Clinical Trials. Journal of Bone and Mineral Research, 30(12), 2168-2178. [More Information]
  • Salis (nee Sainsbury), A., Evans, I., Wood, R., Seimon, R., King, N., Hills, A., Byrne, N. (2015). Effect of a 4-week weight maintenance diet on circulating hormone levels: implications for clinical weight loss trials. Clinical Obesity, 5(2), 79-86. [More Information]
  • Fernando, H., Zibellini, J., Hsu, M., Seimon, R., Nguyen, A., Salis (nee Sainsbury), A. (2015). The neuropeptide Y-ergic system: Potential therapeutic target against bone loss with obesity treatments. Expert Review of Endocrinology & Metabolism, 10(2), 177-191. [More Information]
  • Seimon, R., Espinoza, D., Ivers, L., Gebski, V., Finer, N., Legler, U., Sharma, A., James, W., Coutinho, W., Caterson, I. (2014). Changes in body weight and blood pressure: paradoxical outcome events in overweight and obese subjects with cardiovascular disease. International Journal of Obesity, 38(9), 1165-1171. [More Information]
  • Seimon, R., Taylor, P., Little, T., Noakes, M., Standfield, S., Clifton, P., Horowitz, M., Feinle-Bisset, C. (2014). Effects of acute and longer-term dietary restriction on upper gut motility, hormone, appetite, and energy-intake responses to duodenal lipid in lean and obese men. American Journal of Clinical Nutrition, 99(1), 24-34. [More Information]
  • Seimon, R., Hostland, N., Silveira, S., Gibson, A., Salis (nee Sainsbury), A. (2013). Effects of energy restriction on activity of the hypothalamo-pituitary-adrenal axis in obese humans and rodents: implications for diet-induced changes in body composition. Hormone Molecular Biology and Clinical Investigation, 15(2), 71-80. [More Information]
  • Seimon, R., Brennan, I., Russo, A., Little, T., Jones, K., Stanfield, S., Wishart, J., Horowitz, M., Feinle-Bisset, C. (2013). Gastric emptying, mouth-to-cecum transit, and glycemic, insulin, incretin, and energy intake responses to a mixed-nutrient liquid in lean, overweight, and obese males. American Journal of Physiology: Endocrinology and Metabolism, 304(3), E294-E300. [More Information]
  • Seimon, R., Lange, K., Little, T., Brennan, I., Pilichiewicz, A., Feltrin, K., Smeets, A., Horowitz, M., Feinle-Bisset, C. (2010). Pooled-data analysis identifies pyloric pressures and plasma cholecystokinin concentrations as major determinants of acute energy intake in healthy, lean men. American Journal of Clinical Nutrition, 92(1), 61-68. [More Information]
  • Seimon, R., Wooster, T., Otto, B., Golding, M., Day, L., Little, T., Horowitz, M., Clifton, P., Feinle-Bisset, C. (2009). The droplet size of intraduodenal fat emulsions influences antropyloroduodenal motility, hormone release, and appetite in healthy males. American Journal of Clinical Nutrition, 89(6), 1729-1736. [More Information]

Conferences

  • Seimon, R., Stewart, J., Otto, B., Keast, R., Clifton, P., Feinle-Bisset, C. (2010). Marked differences in gustatory and gastrointestinal sensitivity to oleic acid between lean and obese men. 18th Annual Meeting of the Society for the Study of Ingestive Behavior (SSIB).
  • Seimon, R., Wooster, T., Otto, B., Golding, M., Day, L., Little, T., Horowitz, M., Clifton, P., Feinle-Bisset, C. (2009). The particle size of intraduodenal (ID) fat emulsions modifies antropyloroduodenal (APD) motility, hormone release and appetite in healthy males. Digestive Disease Week (DDW).
  • Seimon, R., Feltrin, K., Brennan, J., Wishart, M., Horowitz, C., Feinle-Bisset, C. (2008). Effects of intraduodenal infusion of varying combinations of lipid and carbohydrate on antropyloroduodenal motility, hormone release and appetite in healthy males. 16th Annual Meeting of the Society for the Study of Ingestive Behavior (SSIB).

2018

  • Seimon, R., Wild-Taylor, A., Gibson, A., Harper, C., McClintock, S., Fernando, H., Hsu, M., Quinto da Luz, F., Keating, S., Johnson, N., Grieve, S., Markovic, T., Caterson, I., Sainsbury, A., et al (2018). Less waste on waist measurements: Determination of optimal waist circumference measurement site to predict visceral adipose tissue in postmenopausal women with obesity. Nutrients, 10(2:239). [More Information]
  • Seimon, R., Gibson, A., Harper, C., Keating, S., Johnson, N., Quinto da Luz, F., Fernando, H., Skilton, M., Markovic, T., Caterson, I., Salis (nee Sainsbury), A., et al (2018). Rationale and Protocol for a Randomized Controlled Trial Comparing Fast versus Slow Weight Loss in Postmenopausal Women with Obesity-The TEMPO Diet Trial. Healthcare, 6(3), 1-28. [More Information]
  • Hsu, M., Harper, C., Gibson, A., Sweeting, A., McBride, J., Markovic, T., Caterson, I., Byrne, N., Salis (nee Sainsbury), A., Seimon, R. (2018). Recruitment Strategies for a Randomised Controlled Trial Comparing Fast Versus Slow Weight Loss in Postmenopausal Women with Obesity-The TEMPO Diet Trial. Healthcare, 6(3), 1-17. [More Information]

2017

  • Alharbi, T., Wong, J., Markovic, T., Yue, D., Wu, T., Brooks, B., Hetherington, J., Seimon, R., Gibson, A., Toth, K., Silveira, S., Salis (nee Sainsbury), A., Little, T. (2017). Brief report: Ramadan as a model of intermittent fasting: Effects on body composition, metabolic parameters, gut hormones and appetite in adults with and without type 2 diabetes mellitus. Obesity Medicine, 6, 15-17. [More Information]
  • Maggioni, A., Caterson, I., Urso, R., Coutinho, W., Finer, N., Van Gaal, L., Legler, U., Sharma, A., Seimon, R., Sweeting, A., et al (2017). Relation between weight loss and causes of death in patients with cardiovascular disease: Finding from the SCOUT trial. Journal of Cardiovascular Medicine (Hagerstown), 18(3), 144-151. [More Information]

2016

  • Gibson, A., Hsu, M., Rangan, A., Seimon, R., Lee, C., Das, A., Finch, C., Salis (nee Sainsbury), A. (2016). Accuracy of hands v. household measures as portion size estimation aids. Journal of Nutritional Science, 5, 1-11. [More Information]
  • Schober, G., Lange, K., Steinert, R., Hutchison, A., Luscombe-Marsh, N., Landrock, M., Horowitz, M., Seimon, R., Feinle-Bisset, C. (2016). Contributions of upper gut hormones and motility to the energy intake-suppressant effects of intraduodenal nutrients in healthy, lean men - a pooled-data analysis. Physiological Reports, 4(17), 1-14. [More Information]
  • Zibellini, J., Seimon, R., Lee, C., Gibson, A., Hsu, M., Salis (nee Sainsbury), A. (2016). Effect of diet-induced weight loss on muscle strength in adults with overweight or obesity - a systematic review and meta-analysis of clinical trials. Obesity Reviews, 17(8), 647-663. [More Information]
  • Harper, C., Pattinson, A., Fernando, H., Zibellini, J., Seimon, R., Salis (nee Sainsbury), A. (2016). Effects of obesity treatments on bone mineral density, bone turnover and fracture risk in adults with overweight or obesity. Hormone Molecular Biology and Clinical Investigation, 28(3), 133-149. [More Information]
  • Gibson, A., Seimon, R., Franklin, J., Markovic, T., Byrne, N., Manson, E., Caterson, I., Salis (nee Sainsbury), A. (2016). Fast versus slow weight loss: development process and rationale behind the dietary interventions for the TEMPO Diet Trial. Obesity Science & Practice, 2(2), 162-173. [More Information]
  • Seimon, R., Shi, Y., Slack, K., Lee, K., Fernando, H., Nguyen, A., Zhang, L., Lin, S., Enriquez, R., Lau, J., Salis (nee Sainsbury), A., et al (2016). Intermittent Moderate Energy Restriction Improves Weight Loss Efficiency in Diet-Induced Obese Mice. PloS One, 11(1), 1-20. [More Information]

2015

  • Seimon, R., Espinoza, D., Finer, N., James, W., Legler, U., Coutinho, W., Sharma, A., Van Gaal, L., Maggioni, A., Sweeting, A., Gebski, V., Caterson, I., et al (2015). Changes in body weight and pulse: outcome events in overweight and obese subjects with cardiovascular disease in the SCOUT trial. International Journal of Obesity, 39(5), 849-857. [More Information]
  • Seimon, R., Roekenes, J., Zibellini, J., Zhu, B., Gibson, A., Hills, A., Wood, R., King, N., Byrne, N., Salis (nee Sainsbury), A. (2015). Do intermittent diets provide physiological benefits over continuous diets for weight loss? A systematic review of clinical trials. Molecular And Cellular Endocrinology, 418, 153-172. [More Information]
  • Gibson, A., Seimon, R., Lee, C., Ayre, J., Franklin, J., Markovic, T., Caterson, I., Salis (nee Sainsbury), A. (2015). Do ketogenic diets really suppress appetite? A systematic review and meta-analysis. Obesity Reviews, 16(1), 64-76. [More Information]
  • Zibellini, J., Seimon, R., Lee, C., Gibson, A., Hsu, M., Shapses, S., Nguyen, T., Sainsbury, A. (2015). Does Diet-Induced Weight Loss Lead to Bone Loss in Overweight or Obese Adults? A Systematic Review and Meta-Analysis of Clinical Trials. Journal of Bone and Mineral Research, 30(12), 2168-2178. [More Information]
  • Salis (nee Sainsbury), A., Evans, I., Wood, R., Seimon, R., King, N., Hills, A., Byrne, N. (2015). Effect of a 4-week weight maintenance diet on circulating hormone levels: implications for clinical weight loss trials. Clinical Obesity, 5(2), 79-86. [More Information]
  • Fernando, H., Zibellini, J., Hsu, M., Seimon, R., Nguyen, A., Salis (nee Sainsbury), A. (2015). The neuropeptide Y-ergic system: Potential therapeutic target against bone loss with obesity treatments. Expert Review of Endocrinology & Metabolism, 10(2), 177-191. [More Information]

2014

  • Seimon, R., Espinoza, D., Ivers, L., Gebski, V., Finer, N., Legler, U., Sharma, A., James, W., Coutinho, W., Caterson, I. (2014). Changes in body weight and blood pressure: paradoxical outcome events in overweight and obese subjects with cardiovascular disease. International Journal of Obesity, 38(9), 1165-1171. [More Information]
  • Seimon, R., Taylor, P., Little, T., Noakes, M., Standfield, S., Clifton, P., Horowitz, M., Feinle-Bisset, C. (2014). Effects of acute and longer-term dietary restriction on upper gut motility, hormone, appetite, and energy-intake responses to duodenal lipid in lean and obese men. American Journal of Clinical Nutrition, 99(1), 24-34. [More Information]

2013

  • Seimon, R., Hostland, N., Silveira, S., Gibson, A., Salis (nee Sainsbury), A. (2013). Effects of energy restriction on activity of the hypothalamo-pituitary-adrenal axis in obese humans and rodents: implications for diet-induced changes in body composition. Hormone Molecular Biology and Clinical Investigation, 15(2), 71-80. [More Information]
  • Seimon, R., Brennan, I., Russo, A., Little, T., Jones, K., Stanfield, S., Wishart, J., Horowitz, M., Feinle-Bisset, C. (2013). Gastric emptying, mouth-to-cecum transit, and glycemic, insulin, incretin, and energy intake responses to a mixed-nutrient liquid in lean, overweight, and obese males. American Journal of Physiology: Endocrinology and Metabolism, 304(3), E294-E300. [More Information]

2010

  • Seimon, R., Stewart, J., Otto, B., Keast, R., Clifton, P., Feinle-Bisset, C. (2010). Marked differences in gustatory and gastrointestinal sensitivity to oleic acid between lean and obese men. 18th Annual Meeting of the Society for the Study of Ingestive Behavior (SSIB).
  • Seimon, R., Lange, K., Little, T., Brennan, I., Pilichiewicz, A., Feltrin, K., Smeets, A., Horowitz, M., Feinle-Bisset, C. (2010). Pooled-data analysis identifies pyloric pressures and plasma cholecystokinin concentrations as major determinants of acute energy intake in healthy, lean men. American Journal of Clinical Nutrition, 92(1), 61-68. [More Information]

2009

  • Seimon, R., Wooster, T., Otto, B., Golding, M., Day, L., Little, T., Horowitz, M., Clifton, P., Feinle-Bisset, C. (2009). The droplet size of intraduodenal fat emulsions influences antropyloroduodenal motility, hormone release, and appetite in healthy males. American Journal of Clinical Nutrition, 89(6), 1729-1736. [More Information]
  • Seimon, R., Wooster, T., Otto, B., Golding, M., Day, L., Little, T., Horowitz, M., Clifton, P., Feinle-Bisset, C. (2009). The particle size of intraduodenal (ID) fat emulsions modifies antropyloroduodenal (APD) motility, hormone release and appetite in healthy males. Digestive Disease Week (DDW).

2008

  • Seimon, R., Feltrin, K., Brennan, J., Wishart, M., Horowitz, C., Feinle-Bisset, C. (2008). Effects of intraduodenal infusion of varying combinations of lipid and carbohydrate on antropyloroduodenal motility, hormone release and appetite in healthy males. 16th Annual Meeting of the Society for the Study of Ingestive Behavior (SSIB).
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