Associate Professor Renae Monique Ryan
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Associate Professor
D06 - Blackburn Building |
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Themes | Research interests | Grants | PhD & Masters' project opportunities | Honours project opportunities | Keywords
Research interests
Dr. Ryan's research focuses on understanding the way in which proteins move molecules across the cell membrane. In particular, she studies transporters for the neurotransmitters glutamate and glycine that play an important role in regulating normal neurotransmission in the brain. The dysfunction of these transporters has been implicated in disease states such as Alzheimer's disease, schizophrenia and ischemia following a stroke. Dr. Ryan uses a variety of biochemical and molecular techniques to try and understand the mechanism of transport and also how drugs interact with these proteins.
Current national competitive grants*
2012
Lipid Modulation of Glycine Transporters
Vandenberg R, Ryan R
NHMRC Project Grants ($356,175 over 3 years)
2009
The Molecular mechanism of ion-coupled transport in the brain
Ryan R
NHMRC Career Development Award ($370,000 over 5 years)
* Grants administered through the University of Sydney
Honours project opportunities
Defining Drug Binding Sites on GLYT1
Understanding the mechanism of transport by the glutamate transporter family using chimeras and site-directed mutagenesis
Characterization of Drug Binding sites on Glycine Transporters