Emeritus Professor Ross Smith

Emeritus Professor
Surgery, Northern Clinical School

Telephone 9437 3511

Map

Biographical details

Ross Smith is Head, Cancer Surgery Research Laboratory at the Kolling Institute, University of Sydney / RNSH.

Over 30 years as a surgeon scientist, Professor Smith has made a major contribution to the clinical management of patients with pancreatic cancer and other abdominal conditions needing complex hospital care. His research career began at Concord Hospital, caring for patients with severe surgical debilitation, setting up the parenteral nutrition service and pioneering major resections for pancreatic cancer.

On appointment to RNSH, Professor Smith set up a laboratory to improve the nutritional outcome of ill surgical patients, which was then a major problem. As well as managing his research, a heavy operative load and undergraduate and postgraduate teaching, Professor Smith was Sub-Dean, Northern Clinical School. He is a member of the RACS Court of Examiners and has authored over 150 papers in peer-reviewed journals.

In 1998 Ross Smith redirected his laboratory to better understand the biology of abdominal cancers. Supported by his Cancer Surgery Research Foundation (CanSur), the laboratory has supported the ten students to obtain postgraduate degrees.

Achievements include The role of epidural anaesthesia in reducing pain and loss of muscle perioperatively, Extra growth hormone treatment maintains muscle mass during surgery, Importance of the uPA system as driver of the malignant process on cancer cells, Serum protein profiling is diagnostic of pancreatic cancer, Apo AII is independently diagnostic of pancreatic cancer, CA 19.9 is elevated up to 2 years before pancreatic cancer presentation and recently, Successful prediction of effective treatment using xenografts of patients’ cancer tissue in the laboratory.

Research interests

Current work is on the development of biological nanoparticle therapy for cancer.

Selected grants

2017

  • Treating pancreatic cancer with FXYD3 peptide analogues; Rasmussen H, Baxter R, Smith R, Liu C, Howell V; Avner Pancreatic Cancer Foundation/Research support.

2015

  • Streamlining specimen preparation for researchers from samples stored in biobanks; Marsh D, Baxter R, Smith R, Howell V, Benn D, Engel A; Cancer Institute NSW/Equipment Grant.

2012

  • Bruker Daltonics autoflex speed MALDI-TOF/TOF mass spectrometer; Baxter R, Halliday G, Marsh D, Gill A, Clarke S, Smith R, Little C, Jackson C, O'Neill C, Murphy C, Sharland A, Chadban S, Mason R, Assinder S, Verdurand M, Richardson D, Machaalani R, Hambly B, Chan-Ling T, Dos Remedios C, Holsinger D, Lay P; National Health and Medical Research Council (NHMRC)/Equipment Grants.

2007

  • Tumour bank officer in the Northern Hub; Smith R, Marsh D, Baxter R, Robinson B; Cancer Institute NSW/Infrastructure Grant.

2005

  • Cancer functional genomics in the northern hub; Baxter R, Marsh D, Smith R; Cancer Institute NSW/Research Grant.

2004

  • The role of psychosocial variables in the diagnosis and outcome of breast cancer; Tennant C, Kossoff M, Dunn S, Smith R; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Does growth hormone improve the effectiveness of intravenous nutrition after abdominal surgery; Smith R, Allen B; National Health and Medical Research Council (NHMRC)/Project Grants.

2000

  • The role of psychosocial variables in the diagnosis and outcome of breast cancer; Tennant C, Kossoff M, Jones M, Smith R; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Does growth hormone improve the effectiveness of intravenous nutrition after abdominal surgery; Smith R, Allen B; National Health and Medical Research Council (NHMRC)/Project Grants.

Selected publications

Download citations: PDF RTF Endnote

Book Chapters

  • Smith, R. (2010). Peri-operative Management of Patients with GI Malignancy: The Interdisciplinary Approach. In Monica Robotin, Ian Olver, Afaf Girgis (Eds.), When Cancer Crosses Disciplines: A Physicians Handbook, (pp. 439-463). London: Imperial College Press. [More Information]
  • Smith, R. (2009). Novel Biomarkers for Biliary Tract Cancer. In Charles R. Thomas, Jr., Clifton David Fuller (Eds.), Biliary Tract And Gallbladder Cancer: Diagnosis And Therapy, (pp. 65-76). New York: Demos Medical Publishing.

Journals

  • Brown, K., Xue, A., Julovi, S., Gill, A., Pavlakis, N., Samra, J., Smith, R., Hugh, T. (2018). Using patient-derived xenograft models of colorectal liver metastases to predict chemosensitivity. Journal of Surgical Research, 227, 158-167. [More Information]
  • Nikfarjam, M., Wilson, J., Smith, R. (2017). Diagnosis and management of pancreatic exocrine insufficiency. Medical Journal of Australia, 207(4), 161-165. [More Information]
  • Schlichtemeier, S., Pang, T., Williams, N., Gill, A., Smith, R., Samra, J., Lam, V., Hollands, M., Richardson, A., Pleass, H., Hugh, T., et al (2016). A pre-operative clinical model to predict microvascular invasion and long-term outcome after resection of hepatocellular cancer: The Australian experience. European Journal of Surgical Oncology, 42(10), 1576-1583. [More Information]
  • Julovi, S., Xue, A., Thanh LE, T., Gill, A., Bulanadi, J., Patel, M., Waddington, L., Rye, K., Moghaddam, M., Smith, R. (2016). Apolipoprotein A-II Plus Lipid Emulsion Enhance Cell Growth via SR-B1 and Target Pancreatic Cancer In Vitro and In Vivo. PloS One, 11(3), 1-14. [More Information]
  • Andrici, J., Goeppert, B., Sioson, L., Clarkson, A., Renner, M., Stenzinger, A., Tayao, M., Watson, N., Farzin, M., Toon, C., Smith, R., Mittal, A., Samra, J., Hugh, T., Gill, A., et al (2016). Loss of BAP1 Expression Occurs Frequently in Intrahepatic Cholangiocarcinoma. Medicine, 95(2), 1-8. [More Information]
  • Brown, K., Xue, A., Mittal, A., Samra, J., Smith, R., Hugh, T. (2016). Patient-derived xenograft models of colorectal cancer in preclinical research: A systematic review. Oncotarget, 7(40), 66212-66225. [More Information]
  • Smith, R., Smith, S., Wilson, J., Pearce, C., Wray, N., Vo, R., Chen, J., Ooi, C., Oliver, M., Katz, T., et al (2016). Summary and recommendations from the Australasian guidelines for the management of pancreatic exocrine insufficiency. Pancreatology, 16(2), 164-180. [More Information]
  • Wong, M., Xue, A., Baxter, R., Pavlakis, N., Smith, R. (2016). Upstream and Downstream Co-inhibition of Mitogen-Activated Protein Kinase and PI3K/Akt/mTOR Pathways in Pancreatic Ductal Adenocarcinoma. NeoPlasia: an international journal of oncology research, 18(7), 425-435. [More Information]
  • Xue, A., Julovi, S., Hugh, T., Samra, J., Wong, M., Gill, A., Toon, C., Smith, R. (2015). A patient-derived subrenal capsule xenograft model can predict response to adjuvant therapy for cancers in the head of the pancreas. Pancreatology, 15(4), 397-404. [More Information]
  • O'Brien, D., Sandanayake, N., Jenkinson, C., Gentry-Maharaj, A., Apostolidou, S., Fourkala, E., Camuzeaux, S., Blyuss, O., Gunu, R., Smith, R., et al (2015). Serum CA19-9 is significantly upregulated up to 2 years before diagnosis with pancreatic cancer: implications for early disease detection. Clinical Cancer Research, 21(3), 622-631. [More Information]
  • Wong, M., Xue, A., Julovi, S., Pavlakis, N., Samra, J., Hugh, T., Gill, A., Peters, L., Baxter, R., Smith, R. (2014). Cotargeting of epidermal growth factor receptor and PI3K overcomes PI3K-Akt oncogenic dependence in pancreatic ductal adenocarcinoma. Clinical Cancer Research, 20(10), 4047-4058. [More Information]
  • Pillai, U., Phillips, K., Wilkins, G., Baxter, R., Benn, D., Parker, N., Smith, R., Marsh, D. (2014). Factors that may influence the willingness of cancer patients to consent for biobanking. Biopreservation and Biobanking, 12(6), 409-414. [More Information]
  • Sanadanayake, N., Camuzeaux, S., Sinclair, J., Blyuss, O., Andreola, F., Chapman, M., Webster, G., Smith, R., Timms, J., Pereira, S. (2014). Identification of potential serum peptide biomarkers of biliary tract cancer using MALDI MS profiling. BMC Clinical Pathology, 14, 1-11. [More Information]
  • Creighton, N., Smith, R., Currow, D. (2014). Survival, mortality and morbidity outcomes after oesophagogastric cancer surgery in New South Wales, 2001-2008. Medical Journal of Australia, 201(8), 447-447. [More Information]
  • Smith, R., Creighton, N., Lord, R., Merrett, N., Keogh, G., Liauw, W., Currow, D. (2014). Survival, mortality and morbidity outcomes after oesophagogastric cancer surgery in New South Wales, 2001-2008. Medical Journal of Australia, 200(7), 408-413. [More Information]
  • Xue, A., Gandy, R., Chung, L., Baxter, R., Smith, R. (2012). Discovery of diagnostic biomarkers for pancreatic cancer in immunodepleted serum by SELDI-TOF MS. Pancreatology, 12(2), 124-129. [More Information]
  • Aslani, A., Roach, P., Smith, R. (2012). Long-term changes in body composition after pancreaticoduodenectomy. ANZ Journal of Surgery, 82(3), 173-178. [More Information]
  • Xue, A., Chang, J., Chung, L., Samra, J., Hugh, T., Gill, A., Butterini, G., Baxter, R., Smith, R. (2012). Serum apolipoprotein C-II is prognostic for survival after pancreatic resection for adenocarcinoma. British Journal of Cancer, 107(11), 1883-1891. [More Information]
  • Sanadanayake, N., Sinclair, J., Andreola, F., Chapman, M., Xue, A., Webster, G., Clarkson, A., Gill, A., Norton, I., Smith, R., et al (2011). A combination of serum leucine-rich α-2-glycoprotein 1, CA19-9 and interleukin-6 differentiate biliary tract cancer from benign biliary strictures. British Journal of Cancer, 105(9), 1370-1378. [More Information]
  • Pang, T., Fung, T., Samra, J., Hugh, T., Smith, R. (2011). Pyogenic liver abscess: An audit of 10 years' experience. World Journal of Gastroenterology, 17(12), 1622-1630. [More Information]
  • Allen, B., Rizvi, S., Qu, C., Smith, R. (2011). Targeted Alpha Therapy Approach to the Management of Pancreatic Cancer. Cancers, 3(2), 1821-1843. [More Information]
  • Smith, R. (2010). Critical evaluation: Perioperative intravenous glutamine supplementation. ANZ Journal of Surgery, 80(7-8), 559-560. [More Information]
  • Xue, A., Scarlett, C., Chung, L., Butturini, G., Scarpa, A., Gandy, R., Wilson, S., Baxter, R., Smith, R. (2010). Discovery of serum biomarkers for pancreatic adenocarcinoma using proteomic analysis. British Journal of Cancer, 103(3), 391-400. [More Information]
  • Gill, A., Chou, A., Vilain, R., Clarkson, A., Lui, M., Jin, R., Tobias, V., Samra, J., Goldstein, D., Smith, C., Smith, R., Sywak, M., Sidhu, S., Robinson, B., Eckstein, R., Benn, D., Clifton-Bligh, R., et al (2010). Immunohistochemistry for SDHB Divides Gastrointestinal Stromal Tumors (GISTs) into 2 Distinct Types. American Journal of Surgical Pathology, 34(5), 636-644. [More Information]
  • Aslani, A., Gill, A., Roach, P., Allen, B., Smith, R. (2010). Preoperative body composition is influenced by the stage of operable pancreatic adenocarcinoma but does not predict survival after Whipple's procedure. HPB, 12(5), 325-333. [More Information]
  • Smith, R., Ledgard, J., Doig, G., Chesher, D., Smith, S. (2009). An effective automated nutrition screen for hospitalized patients. Nutrition: an international journal of applied and basic nutritional science, 25(3), 309-315. [More Information]
  • Xue, A., Xue, M., Jackson, C., Smith, R. (2009). Suppression of urokinase plasminogen activator receptor inhibits proliferation and migration of pancreatic adenocarcinoma cells via regulation of ERK/p38 signaling. The International Journal of Biochemistry and Cell Biology, 41(8-9), 1731-1738. [More Information]
  • Gill, A., Johns, A., Eckstein, R., Samra, J., Kaufman, A., Chang, D., Merrett, N., Cosman, P., Smith, R., Biankin, A., et al (2009). Synoptic reporting improves histopathological assessment of pancreatic resection specimens. Pathology, 41(2), 161-167. [More Information]
  • Gillanders, L., Angstmann, K., Ball, P., Chapman-Kiddell, C., Hardy, G., Hope, J., Smith, R., Strauss, B., Russell, D. (2008). AuSPEN clinical practice guideline for home parenteral nutrition patients in Australia and New Zealand. Nutrition: an international journal of applied and basic nutritional science, 24(10), 998-1012. [More Information]
  • Gananadha, S., Samra, J., Smith, G., Smith, R., Liebman, S., Hugh, T. (2008). Laparoscopic ePTFE mesh repair of incisional and ventral hernias. ANZ Journal of Surgery, 78(10), 907-913. [More Information]
  • Xue, A., Scarlett, C., Jackson, C., Allen, B., Smith, R. (2008). Prognostic significance of growth factors and the urokinase-type plasminogen activator system in pancreatic ductal adenocarcinoma. Pancreas, 36(2), 160-167. [More Information]
  • Kuo, S., Gananadha, S., Scarlett, C., Gill, A., Smith, R. (2008). Sporadic Pancreatic Polypeptide Secreting Tumors (PPomas) of the Pancreas. World Journal of Surgery, 32(8), 1815-1822. [More Information]
  • Scarlett, C., Samra, J., Xue, A., Baxter, R., Smith, R. (2007). Classification of pancreatic cystic lesions using seldi-tof mass spectrometry. ANZ Journal of Surgery, 77(8), 648-653. [More Information]
  • Smith, R., Xue, A., Gill, A., Scarlett, C., Saxby, A., Clarkson, A., Hugh, T. (2007). High Expression of Plasminogen Activator Inhibitor-2 (PAI-2) is a Predictor of Improved Survival in Patients with Pancreatic Adenocarcinoma. World Journal of Surgery, 31(3), 493-502. [More Information]
  • Smith, R., Pender, S. (2007). Hp06 pancreatic abscess: results of a surgeon's protocol. ANZ Journal of Surgery, 77(1), A41-A41. [More Information]
  • Baxter, R., Smith, R., Scarlett, C., Xue, A., Butturini, G., Scarpa, A. (2007). Hp07 proteomic identification of serum markers of pancreatic adenocarcinoma using seldi-tof ms. ANZ Journal of Surgery, 77(suppl.1), A41-A41. [More Information]
  • Smith, R. (2007). Infrared spectroscopy and pancreatitis. ANZ Journal of Surgery, 77(5), 313. [More Information]
  • O'Leary, M., Xue, A., Scarlett, C., Sevette, A., Kee, A., Smith, R. (2007). Parenteral versus enteral nutrition: effect on serum cytokines and the hepatic expression of mRNA of suppressor of cytokine signaling proteins, insulin-like growth factor-1 and the growth hormone receptor in rodent sepsis. Critical Care, 11(4), 1-8. [More Information]
  • Samra, J., Gananadha, S., Gill, A., Smith, R., Hugh, T. (2006). Modified extended pancreatoduodenectomy: en bloc resection of the peripancreatic retroperitoneal tissue and the head of pancreas. ANZ Journal of Surgery, 76(11), 1017-1020. [More Information]
  • Scarlett, C., Smith, R., Saxby, A., Nielsen, A., Samra, J., Wilson, S., Baxter, R. (2006). Proteomic classification of pancreatic adenocarcinoma tissue using protein chip technology. Gastroenterology, 130(6), 1670-1678. [More Information]
  • Bell, C., Samra, J., Hugh, T., Baxter, R., Smith, R., Saxby, A., Nielsen, A., Scarlett, C. (2006). Proteomic profiling of cholangiocarcinoma: Diagnostic potential of SELDI-TOF MS in malignant bile duct stricture. Hepatology, 44(3), 658-666. [More Information]
  • Smith, R., Saxby, A., Nielsen, A., Scarlett, C., Clarkson, A., Morey, A., Gill, A. (2005). Assessment of HER-2 status in pancreatic adenocarcinoma: correlation of immunohistochemistry, quantitative real-time RT-PCR, and FISH with aneuploidy and survival. American Journal of Surgical Pathology, 29(9), 1125-1134. [More Information]
  • Sevette, A., Smith, R., Aslani, A., Kee, A., Hansen, R., Barratt, S., Baxter, R. (2005). Does growth hormone allow more efficient nitrogen sparing in postoperative patients requiring parenteral nutrition? A double-blind, placebo-controlled randomised trial. Clinical Nutrition, 24(6), 943-955. [More Information]
  • Qu, C., Song, Y., Rizvi, S., Li, Y., Smith, R., Perkins, A., Morgenstern, A., Brechbiel, M., Allen, B. (2005). In Vivo and in Vitro Inhibition of Pancreatic Cancer Growth by Targeted Alpha Therapy Using (213)Bi-CHX.A''-C595. Cancer Biology and Therapy, 4(8), 848-853. [More Information]
  • Samra, J., Sved, P., Sullivan, D., Hugh, T., Smith, R. (2005). Lipid metabolism in omental adipose tissue during operative surgery. Journal of Surgical Research, 124(1), 23-28. [More Information]
  • Qu, C., Song, E., Li, Y., Rizvi, S., Raja, C., Smith, R., Morgenstern, A., Apostolidis, C., Allen, B. (2005). Pre-clinical study of Bi-213 labeled PAI2 for the control of micrometastatic pancreatic cancer. Clinical and Experimental Metastasis, 22(7), 575-586. [More Information]
  • Saxby, A., Samra, J., Hugh, T., Smith, R. (2005). Role of duodenojejunostomy in distal duodenal obstruction. ANZ Journal of Surgery, 75(3), 177-178. [More Information]
  • Smith, R., Southwell-Keely, J., Chesher, D. (2005). Should serum pancreatic lipase replace serum amylase as a biomarker of acute pancreatitis? ANZ Journal of Surgery, 75(6), 399-404. [More Information]
  • Nielsen, A., Scarlett, C., Samra, J., Gill, A., Li, Y., Allen, B., Smith, R. (2005). Significant overexpression of urokinase-type plasminogen activator in pancreatic adenocarcinoma using real-time quantitative reverse transcription polymerase chain reaction. Journal of Gastroenterology and Hepatology, 20(2), 256-263. [More Information]
  • Scarlett, C., O'Leary, M., Lee, A., Nielsen, A., Sevette, A., Baxter, R., Smith, R. (2004). A Study Of Parenteral Versus Enteral Nutrition Following Caecal Ligation And Puncture In The Rat: Influence On Survival And Tissue Protein Turnover. Clinical Nutrition, 23(5), 1135-1145. [More Information]
  • Callinan, A., Samra, J., Smith, R. (2004). Hemosuccus Pancreaticus. ANZ Journal of Surgery, 74(5), 395-397. [More Information]
  • Qu, C., Li, Y., Song, Y., Rizvi, S., Raja, C., Zhang, D., Samra, J., Smith, R., Perkins, A., Apostolidis, C., et al (2004). Muc1 Expression In Primary And Metastatic Pancreatic Cancer Cells For In Vitro Treatment By (213)Bi-C595 Radioimmunoconjugate. British Journal of Cancer, 91(12), 2086-2093. [More Information]
  • Smith, R., Barnsley, L., Kannangara, S., Mace, A. (2004). Rheumatological Prescribing In Athletes: A Review Of The New World Anti-Doping Agency Guidelines. Rheumatology (Print Edition), 43(12), 1473-1475. [More Information]
  • Smith, R. (2003). Cholecystectomy and duodenogastric relfux. ANZ Journal of Surgery, 11, 369-370. [More Information]
  • Samra, J., Smith, R. (2003). Control of venous bleeding during dissection near the head of the pancreas. ANZ Journal of Surgery, 11, 856-857. [More Information]
  • Rindani, R., Roche, J., Hugh, T., Roach, P., Smith, R. (2002). 131I Lipiodol therapy for unresectable hepatocellular carcinoma. ANZ Journal of Surgery, 72(3), 210-214. [More Information]
  • Kee, A., Taylor, A., Carlsson, A., Sevette, A., Smith, R., Thompson, M. (2002). IGF-1 has no effect on post exercise suppression of the ubiquitin-proteasome system in rat skeletal muscle. Journal of Applied Physiology, 96(2), 2277-2284.
  • Barratt, S., Smith, R., Kee, A., Mather, L., Cousins, M. (2002). Multimodal Analgesia and Intravenous Nutrition Preserves Total Body Protein Following Major Upper Gastrointestinal Surgery. Regional Anesthesia and Pain Medicine, 27(1), 15-22. [More Information]
  • Sevette, A., Baxter, R., Smith, R., Kee,, A., Carlsson, A. (2001). Parenteral nutrition with lipid or glucose suppresses liver growth and response to GH in adolescent male rats. American Journal of Physiology - Endocrinology and Metabolism, 281.
  • Price, M., Tennant, C., Smith, R., Butow, P., Kennedy, S., Kossoff, M., Dunn, S. (2001). The role of psychosocial factors in the development of breast carcinoma: Part I - The cancer prone personality. Cancer, 91(4), 679-685.
  • Price, M., Tennant, C., Smith, R., Butow, P., Dunn, S., Kennedy, S., Kossoff, M. (2001). The role of psychosocial factors in the development of breast carcinoma: Part II: : Life event stressors, social support, defense style, and emotional control and their interactions. Cancer, 91(4), 686-697.

Conferences

  • Sevette, A., Aslani, A., Hansen, R., Smith, R., Baxter, R. (2002). Preserving muscle mass after abdominal surgery. 6th International Symposium: In VivoBody Composition Studies, 175 Fifth Ave, New York, Ny, 10010: Springer.

2018

  • Brown, K., Xue, A., Julovi, S., Gill, A., Pavlakis, N., Samra, J., Smith, R., Hugh, T. (2018). Using patient-derived xenograft models of colorectal liver metastases to predict chemosensitivity. Journal of Surgical Research, 227, 158-167. [More Information]

2017

  • Nikfarjam, M., Wilson, J., Smith, R. (2017). Diagnosis and management of pancreatic exocrine insufficiency. Medical Journal of Australia, 207(4), 161-165. [More Information]

2016

  • Schlichtemeier, S., Pang, T., Williams, N., Gill, A., Smith, R., Samra, J., Lam, V., Hollands, M., Richardson, A., Pleass, H., Hugh, T., et al (2016). A pre-operative clinical model to predict microvascular invasion and long-term outcome after resection of hepatocellular cancer: The Australian experience. European Journal of Surgical Oncology, 42(10), 1576-1583. [More Information]
  • Julovi, S., Xue, A., Thanh LE, T., Gill, A., Bulanadi, J., Patel, M., Waddington, L., Rye, K., Moghaddam, M., Smith, R. (2016). Apolipoprotein A-II Plus Lipid Emulsion Enhance Cell Growth via SR-B1 and Target Pancreatic Cancer In Vitro and In Vivo. PloS One, 11(3), 1-14. [More Information]
  • Andrici, J., Goeppert, B., Sioson, L., Clarkson, A., Renner, M., Stenzinger, A., Tayao, M., Watson, N., Farzin, M., Toon, C., Smith, R., Mittal, A., Samra, J., Hugh, T., Gill, A., et al (2016). Loss of BAP1 Expression Occurs Frequently in Intrahepatic Cholangiocarcinoma. Medicine, 95(2), 1-8. [More Information]
  • Brown, K., Xue, A., Mittal, A., Samra, J., Smith, R., Hugh, T. (2016). Patient-derived xenograft models of colorectal cancer in preclinical research: A systematic review. Oncotarget, 7(40), 66212-66225. [More Information]
  • Smith, R., Smith, S., Wilson, J., Pearce, C., Wray, N., Vo, R., Chen, J., Ooi, C., Oliver, M., Katz, T., et al (2016). Summary and recommendations from the Australasian guidelines for the management of pancreatic exocrine insufficiency. Pancreatology, 16(2), 164-180. [More Information]
  • Wong, M., Xue, A., Baxter, R., Pavlakis, N., Smith, R. (2016). Upstream and Downstream Co-inhibition of Mitogen-Activated Protein Kinase and PI3K/Akt/mTOR Pathways in Pancreatic Ductal Adenocarcinoma. NeoPlasia: an international journal of oncology research, 18(7), 425-435. [More Information]

2015

  • Xue, A., Julovi, S., Hugh, T., Samra, J., Wong, M., Gill, A., Toon, C., Smith, R. (2015). A patient-derived subrenal capsule xenograft model can predict response to adjuvant therapy for cancers in the head of the pancreas. Pancreatology, 15(4), 397-404. [More Information]
  • O'Brien, D., Sandanayake, N., Jenkinson, C., Gentry-Maharaj, A., Apostolidou, S., Fourkala, E., Camuzeaux, S., Blyuss, O., Gunu, R., Smith, R., et al (2015). Serum CA19-9 is significantly upregulated up to 2 years before diagnosis with pancreatic cancer: implications for early disease detection. Clinical Cancer Research, 21(3), 622-631. [More Information]

2014

  • Wong, M., Xue, A., Julovi, S., Pavlakis, N., Samra, J., Hugh, T., Gill, A., Peters, L., Baxter, R., Smith, R. (2014). Cotargeting of epidermal growth factor receptor and PI3K overcomes PI3K-Akt oncogenic dependence in pancreatic ductal adenocarcinoma. Clinical Cancer Research, 20(10), 4047-4058. [More Information]
  • Pillai, U., Phillips, K., Wilkins, G., Baxter, R., Benn, D., Parker, N., Smith, R., Marsh, D. (2014). Factors that may influence the willingness of cancer patients to consent for biobanking. Biopreservation and Biobanking, 12(6), 409-414. [More Information]
  • Sanadanayake, N., Camuzeaux, S., Sinclair, J., Blyuss, O., Andreola, F., Chapman, M., Webster, G., Smith, R., Timms, J., Pereira, S. (2014). Identification of potential serum peptide biomarkers of biliary tract cancer using MALDI MS profiling. BMC Clinical Pathology, 14, 1-11. [More Information]
  • Creighton, N., Smith, R., Currow, D. (2014). Survival, mortality and morbidity outcomes after oesophagogastric cancer surgery in New South Wales, 2001-2008. Medical Journal of Australia, 201(8), 447-447. [More Information]
  • Smith, R., Creighton, N., Lord, R., Merrett, N., Keogh, G., Liauw, W., Currow, D. (2014). Survival, mortality and morbidity outcomes after oesophagogastric cancer surgery in New South Wales, 2001-2008. Medical Journal of Australia, 200(7), 408-413. [More Information]

2012

  • Xue, A., Gandy, R., Chung, L., Baxter, R., Smith, R. (2012). Discovery of diagnostic biomarkers for pancreatic cancer in immunodepleted serum by SELDI-TOF MS. Pancreatology, 12(2), 124-129. [More Information]
  • Aslani, A., Roach, P., Smith, R. (2012). Long-term changes in body composition after pancreaticoduodenectomy. ANZ Journal of Surgery, 82(3), 173-178. [More Information]
  • Xue, A., Chang, J., Chung, L., Samra, J., Hugh, T., Gill, A., Butterini, G., Baxter, R., Smith, R. (2012). Serum apolipoprotein C-II is prognostic for survival after pancreatic resection for adenocarcinoma. British Journal of Cancer, 107(11), 1883-1891. [More Information]

2011

  • Sanadanayake, N., Sinclair, J., Andreola, F., Chapman, M., Xue, A., Webster, G., Clarkson, A., Gill, A., Norton, I., Smith, R., et al (2011). A combination of serum leucine-rich α-2-glycoprotein 1, CA19-9 and interleukin-6 differentiate biliary tract cancer from benign biliary strictures. British Journal of Cancer, 105(9), 1370-1378. [More Information]
  • Pang, T., Fung, T., Samra, J., Hugh, T., Smith, R. (2011). Pyogenic liver abscess: An audit of 10 years' experience. World Journal of Gastroenterology, 17(12), 1622-1630. [More Information]
  • Allen, B., Rizvi, S., Qu, C., Smith, R. (2011). Targeted Alpha Therapy Approach to the Management of Pancreatic Cancer. Cancers, 3(2), 1821-1843. [More Information]

2010

  • Smith, R. (2010). Critical evaluation: Perioperative intravenous glutamine supplementation. ANZ Journal of Surgery, 80(7-8), 559-560. [More Information]
  • Xue, A., Scarlett, C., Chung, L., Butturini, G., Scarpa, A., Gandy, R., Wilson, S., Baxter, R., Smith, R. (2010). Discovery of serum biomarkers for pancreatic adenocarcinoma using proteomic analysis. British Journal of Cancer, 103(3), 391-400. [More Information]
  • Gill, A., Chou, A., Vilain, R., Clarkson, A., Lui, M., Jin, R., Tobias, V., Samra, J., Goldstein, D., Smith, C., Smith, R., Sywak, M., Sidhu, S., Robinson, B., Eckstein, R., Benn, D., Clifton-Bligh, R., et al (2010). Immunohistochemistry for SDHB Divides Gastrointestinal Stromal Tumors (GISTs) into 2 Distinct Types. American Journal of Surgical Pathology, 34(5), 636-644. [More Information]
  • Smith, R. (2010). Peri-operative Management of Patients with GI Malignancy: The Interdisciplinary Approach. In Monica Robotin, Ian Olver, Afaf Girgis (Eds.), When Cancer Crosses Disciplines: A Physicians Handbook, (pp. 439-463). London: Imperial College Press. [More Information]
  • Aslani, A., Gill, A., Roach, P., Allen, B., Smith, R. (2010). Preoperative body composition is influenced by the stage of operable pancreatic adenocarcinoma but does not predict survival after Whipple's procedure. HPB, 12(5), 325-333. [More Information]

2009

  • Smith, R., Ledgard, J., Doig, G., Chesher, D., Smith, S. (2009). An effective automated nutrition screen for hospitalized patients. Nutrition: an international journal of applied and basic nutritional science, 25(3), 309-315. [More Information]
  • Smith, R. (2009). Novel Biomarkers for Biliary Tract Cancer. In Charles R. Thomas, Jr., Clifton David Fuller (Eds.), Biliary Tract And Gallbladder Cancer: Diagnosis And Therapy, (pp. 65-76). New York: Demos Medical Publishing.
  • Xue, A., Xue, M., Jackson, C., Smith, R. (2009). Suppression of urokinase plasminogen activator receptor inhibits proliferation and migration of pancreatic adenocarcinoma cells via regulation of ERK/p38 signaling. The International Journal of Biochemistry and Cell Biology, 41(8-9), 1731-1738. [More Information]
  • Gill, A., Johns, A., Eckstein, R., Samra, J., Kaufman, A., Chang, D., Merrett, N., Cosman, P., Smith, R., Biankin, A., et al (2009). Synoptic reporting improves histopathological assessment of pancreatic resection specimens. Pathology, 41(2), 161-167. [More Information]

2008

  • Gillanders, L., Angstmann, K., Ball, P., Chapman-Kiddell, C., Hardy, G., Hope, J., Smith, R., Strauss, B., Russell, D. (2008). AuSPEN clinical practice guideline for home parenteral nutrition patients in Australia and New Zealand. Nutrition: an international journal of applied and basic nutritional science, 24(10), 998-1012. [More Information]
  • Gananadha, S., Samra, J., Smith, G., Smith, R., Liebman, S., Hugh, T. (2008). Laparoscopic ePTFE mesh repair of incisional and ventral hernias. ANZ Journal of Surgery, 78(10), 907-913. [More Information]
  • Xue, A., Scarlett, C., Jackson, C., Allen, B., Smith, R. (2008). Prognostic significance of growth factors and the urokinase-type plasminogen activator system in pancreatic ductal adenocarcinoma. Pancreas, 36(2), 160-167. [More Information]
  • Kuo, S., Gananadha, S., Scarlett, C., Gill, A., Smith, R. (2008). Sporadic Pancreatic Polypeptide Secreting Tumors (PPomas) of the Pancreas. World Journal of Surgery, 32(8), 1815-1822. [More Information]

2007

  • Scarlett, C., Samra, J., Xue, A., Baxter, R., Smith, R. (2007). Classification of pancreatic cystic lesions using seldi-tof mass spectrometry. ANZ Journal of Surgery, 77(8), 648-653. [More Information]
  • Smith, R., Xue, A., Gill, A., Scarlett, C., Saxby, A., Clarkson, A., Hugh, T. (2007). High Expression of Plasminogen Activator Inhibitor-2 (PAI-2) is a Predictor of Improved Survival in Patients with Pancreatic Adenocarcinoma. World Journal of Surgery, 31(3), 493-502. [More Information]
  • Smith, R., Pender, S. (2007). Hp06 pancreatic abscess: results of a surgeon's protocol. ANZ Journal of Surgery, 77(1), A41-A41. [More Information]
  • Baxter, R., Smith, R., Scarlett, C., Xue, A., Butturini, G., Scarpa, A. (2007). Hp07 proteomic identification of serum markers of pancreatic adenocarcinoma using seldi-tof ms. ANZ Journal of Surgery, 77(suppl.1), A41-A41. [More Information]
  • Smith, R. (2007). Infrared spectroscopy and pancreatitis. ANZ Journal of Surgery, 77(5), 313. [More Information]
  • O'Leary, M., Xue, A., Scarlett, C., Sevette, A., Kee, A., Smith, R. (2007). Parenteral versus enteral nutrition: effect on serum cytokines and the hepatic expression of mRNA of suppressor of cytokine signaling proteins, insulin-like growth factor-1 and the growth hormone receptor in rodent sepsis. Critical Care, 11(4), 1-8. [More Information]

2006

  • Samra, J., Gananadha, S., Gill, A., Smith, R., Hugh, T. (2006). Modified extended pancreatoduodenectomy: en bloc resection of the peripancreatic retroperitoneal tissue and the head of pancreas. ANZ Journal of Surgery, 76(11), 1017-1020. [More Information]
  • Scarlett, C., Smith, R., Saxby, A., Nielsen, A., Samra, J., Wilson, S., Baxter, R. (2006). Proteomic classification of pancreatic adenocarcinoma tissue using protein chip technology. Gastroenterology, 130(6), 1670-1678. [More Information]
  • Bell, C., Samra, J., Hugh, T., Baxter, R., Smith, R., Saxby, A., Nielsen, A., Scarlett, C. (2006). Proteomic profiling of cholangiocarcinoma: Diagnostic potential of SELDI-TOF MS in malignant bile duct stricture. Hepatology, 44(3), 658-666. [More Information]

2005

  • Smith, R., Saxby, A., Nielsen, A., Scarlett, C., Clarkson, A., Morey, A., Gill, A. (2005). Assessment of HER-2 status in pancreatic adenocarcinoma: correlation of immunohistochemistry, quantitative real-time RT-PCR, and FISH with aneuploidy and survival. American Journal of Surgical Pathology, 29(9), 1125-1134. [More Information]
  • Sevette, A., Smith, R., Aslani, A., Kee, A., Hansen, R., Barratt, S., Baxter, R. (2005). Does growth hormone allow more efficient nitrogen sparing in postoperative patients requiring parenteral nutrition? A double-blind, placebo-controlled randomised trial. Clinical Nutrition, 24(6), 943-955. [More Information]
  • Qu, C., Song, Y., Rizvi, S., Li, Y., Smith, R., Perkins, A., Morgenstern, A., Brechbiel, M., Allen, B. (2005). In Vivo and in Vitro Inhibition of Pancreatic Cancer Growth by Targeted Alpha Therapy Using (213)Bi-CHX.A''-C595. Cancer Biology and Therapy, 4(8), 848-853. [More Information]
  • Samra, J., Sved, P., Sullivan, D., Hugh, T., Smith, R. (2005). Lipid metabolism in omental adipose tissue during operative surgery. Journal of Surgical Research, 124(1), 23-28. [More Information]
  • Qu, C., Song, E., Li, Y., Rizvi, S., Raja, C., Smith, R., Morgenstern, A., Apostolidis, C., Allen, B. (2005). Pre-clinical study of Bi-213 labeled PAI2 for the control of micrometastatic pancreatic cancer. Clinical and Experimental Metastasis, 22(7), 575-586. [More Information]
  • Saxby, A., Samra, J., Hugh, T., Smith, R. (2005). Role of duodenojejunostomy in distal duodenal obstruction. ANZ Journal of Surgery, 75(3), 177-178. [More Information]
  • Smith, R., Southwell-Keely, J., Chesher, D. (2005). Should serum pancreatic lipase replace serum amylase as a biomarker of acute pancreatitis? ANZ Journal of Surgery, 75(6), 399-404. [More Information]
  • Nielsen, A., Scarlett, C., Samra, J., Gill, A., Li, Y., Allen, B., Smith, R. (2005). Significant overexpression of urokinase-type plasminogen activator in pancreatic adenocarcinoma using real-time quantitative reverse transcription polymerase chain reaction. Journal of Gastroenterology and Hepatology, 20(2), 256-263. [More Information]

2004

  • Scarlett, C., O'Leary, M., Lee, A., Nielsen, A., Sevette, A., Baxter, R., Smith, R. (2004). A Study Of Parenteral Versus Enteral Nutrition Following Caecal Ligation And Puncture In The Rat: Influence On Survival And Tissue Protein Turnover. Clinical Nutrition, 23(5), 1135-1145. [More Information]
  • Callinan, A., Samra, J., Smith, R. (2004). Hemosuccus Pancreaticus. ANZ Journal of Surgery, 74(5), 395-397. [More Information]
  • Qu, C., Li, Y., Song, Y., Rizvi, S., Raja, C., Zhang, D., Samra, J., Smith, R., Perkins, A., Apostolidis, C., et al (2004). Muc1 Expression In Primary And Metastatic Pancreatic Cancer Cells For In Vitro Treatment By (213)Bi-C595 Radioimmunoconjugate. British Journal of Cancer, 91(12), 2086-2093. [More Information]
  • Smith, R., Barnsley, L., Kannangara, S., Mace, A. (2004). Rheumatological Prescribing In Athletes: A Review Of The New World Anti-Doping Agency Guidelines. Rheumatology (Print Edition), 43(12), 1473-1475. [More Information]

2003

  • Smith, R. (2003). Cholecystectomy and duodenogastric relfux. ANZ Journal of Surgery, 11, 369-370. [More Information]
  • Samra, J., Smith, R. (2003). Control of venous bleeding during dissection near the head of the pancreas. ANZ Journal of Surgery, 11, 856-857. [More Information]

2002

  • Rindani, R., Roche, J., Hugh, T., Roach, P., Smith, R. (2002). 131I Lipiodol therapy for unresectable hepatocellular carcinoma. ANZ Journal of Surgery, 72(3), 210-214. [More Information]
  • Kee, A., Taylor, A., Carlsson, A., Sevette, A., Smith, R., Thompson, M. (2002). IGF-1 has no effect on post exercise suppression of the ubiquitin-proteasome system in rat skeletal muscle. Journal of Applied Physiology, 96(2), 2277-2284.
  • Barratt, S., Smith, R., Kee, A., Mather, L., Cousins, M. (2002). Multimodal Analgesia and Intravenous Nutrition Preserves Total Body Protein Following Major Upper Gastrointestinal Surgery. Regional Anesthesia and Pain Medicine, 27(1), 15-22. [More Information]
  • Sevette, A., Aslani, A., Hansen, R., Smith, R., Baxter, R. (2002). Preserving muscle mass after abdominal surgery. 6th International Symposium: In VivoBody Composition Studies, 175 Fifth Ave, New York, Ny, 10010: Springer.

2001

  • Sevette, A., Baxter, R., Smith, R., Kee,, A., Carlsson, A. (2001). Parenteral nutrition with lipid or glucose suppresses liver growth and response to GH in adolescent male rats. American Journal of Physiology - Endocrinology and Metabolism, 281.
  • Price, M., Tennant, C., Smith, R., Butow, P., Kennedy, S., Kossoff, M., Dunn, S. (2001). The role of psychosocial factors in the development of breast carcinoma: Part I - The cancer prone personality. Cancer, 91(4), 679-685.
  • Price, M., Tennant, C., Smith, R., Butow, P., Dunn, S., Kennedy, S., Kossoff, M. (2001). The role of psychosocial factors in the development of breast carcinoma: Part II: : Life event stressors, social support, defense style, and emotional control and their interactions. Cancer, 91(4), 686-697.

To update your profile click here. For support on your academic profile contact .