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Dr Samantha Lain

PhD
Research Fellow
Children's Hospital at Westmead Clinical School

Member of the Brain and Mind Centre

Member of the Charles Perkins Centre

Telephone +61 2 8627 4673

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Biographical details

Dr Samantha Lain is a perinatal epidemiologist and Research Fellow with qualifications in Health Sciences, Epidemiology and Economics. She currently works in Child Population and Translational Health Research at the Children's Hospital at Westmead Clinical School. Her research interests include; examining infant health service utilisation, childhood education and developmental outcomes using large linked population-based datasets. Her current postdoctoral fellowship is assessing the impact of newborn screening results on childhood neurodevelopment.

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Current research students

Project title Research student
Understanding the Prevalence of Autoimmune Diseases During Pregnancy and Effects on Pediatric Neurodevelopmental Outcomes Timothy NIELSEN
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Selected grants

2017

  • Evaluation of lower newborn screening thyroid hormone cut-points for treating congenital hypothyroidism; Lain S; Sydney Medical School/Kickstart Grant.

2015

  • Outcomes following a cardiac procedure in the first six years of life; Lain S, Roberts C, Lawley C, Figtree G; HeartKids Australia/Grants in Aid.

2013

  • Infant thyroid hormone levels and long-term child educational outcomes; Lain S; National Health and Medical Research Council (NHMRC)/Early Career Fellowships.

2012

  • Assessing the reporting of stillbirths in population data: trends and recurrence; Roberts C, Lain S, Ford J, Todd A, Morris J; Stillbirth Foundation Australia/Grant-in-Aid.

2011

  • Immediate delivery vs expectant care in women with pre-term prelabour rupture of the membranes close to term- a randomised clinical trial (PPROMT); Morris J, Roberts C, Ford J, Bowen J, Buchanan S, Lain S; National Health and Medical Research Council (NHMRC)/Project Grants.

2010

  • Evaluation of novel antenatal biomarkers for the detection of adverse pregnancy outcomes: a record linkage study; Roberts C, Nassar N, Hadfield R, Tasevski V, Lain S, Algert C; National Health and Medical Research Council (NHMRC)/Project Grants.
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Selected publications

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Journals

  • Bentley, J., Schneuer, F., Lain, S., Martin, A., Gordon, A., Nassar, N. (2018). Neonatal morbidity at term, early child development, and school performance: A population study. Pediatrics, 141(2). [More Information]
  • Schneuer, F., Bentley, J., Davidson, A., Holland, A., Badawi, N., Martin, A., Skowno, J., Lain, S., Nassar, N. (2018). Reply to Ritchie-McLean, Susanna; Wilmshurst, Sally, regarding their comment "Can population cohort studies assess the long?term impact of anaesthesia in children?". Paediatric Anaesthesia, 28(12), 1157-1158. [More Information]
  • Schneuer, F., Bentley, J., Davidson, A., Holland, A., Badawi, N., Martin, A., Skowno, J., Lain, S., Nassar, N. (2018). The impact of general anesthesia on child development and school performance: a population-based study. Paediatric Anaesthesia, 28(6), 528-536. [More Information]
  • Lain, S., Roberts, C., Bond, D., Smith, J., Morris, J. (2017). An economic evaluation of planned immediate versus delayed birth for preterm prelabour rupture of membranes: findings from the PPROMT randomised controlled trial. BJOG, 124(4), 623-630. [More Information]
  • Lain, S., Trumpff, C., Grosse, S., Olivieri, A., Van�Vlie, G. (2017). Are lower TSH cutoffs in neonatal screening for congenital hypothyroidism warranted? European Journal of Endocrinology, 177(5), D1-D12. [More Information]
  • Schneuer, F., Bentley, J., Holland, A., Lain, S., Jamieson, S., Badawi, N., Nassar, N. (2017). Early Childhood Development of Boys with Genital Anomalies. Birth Defects Research, 109(8), 535-542. [More Information]
  • Lawley, C., Lain, S., Figtree, G., Sholler, G., Winlaw, D., Roberts, C. (2017). Mortality, rehospitalizations and costs in children undergoing a cardiac procedure in their first year of life in New South Wales, Australia. International Journal of Cardiology, 241, 156-162. [More Information]
  • Lain, S., Bentley, J., Wiley, V., Roberts, C., Jack, M., Wilcken, B., Nassar, N. (2016). Association between borderline neonatal thyroid-stimulating hormone concentrations and educational and developmental outcomes: a population-based record-linkage study. The Lancet Diabetes & Endocrinology, 4(9), 756-765. [More Information]
  • Stephens, A., Lain, S., Roberts, C., Bowen, J., Nassar, N. (2016). Association of Gestational Age and Severe Neonatal Morbidity with Mortality in Early Childhood. Paediatric and Perinatal Epidemiology, 30(6), 583-593. [More Information]
  • Lawley, C., Lain, S., Figtree, G., Roberts, C. (2016). Health outcomes of infants born to women with heart valve prostheses: complications of prematurity alone? The Journal of Maternal-Fetal and Neonatal Medicine, 29(2), 234-236. [More Information]
  • Stephens, A., Lain, S., Roberts, C., Bowen, J., Nassar, N. (2016). Survival, Hospitalization, and Acute-Care Costs of Very and Moderate Preterm Infants in the First 6 Years of Life: A Population-Based Study. The Journal of Pediatrics, 169, 61-68.e3. [More Information]
  • Lain, S., Roberts, C., Bowen, J., Nassar, N. (2015). Early discharge of infants and risk of readmission for jaundice. Pediatrics, 135(2), 314-321. [More Information]
  • Stephens, A., Lain, S., Roberts, C., Bowen, J., Simpson, A., Nassar, N. (2015). Hospitalisations from 1 to 6 Years of Age: Effects of Gestational Age and Severe Neonatal Morbidity. Paediatric and Perinatal Epidemiology, 29(3), 241-249. [More Information]
  • Lawley, C., Lain, S., Algert, C., Ford, J., Figtree, G., Roberts, C. (2015). Prosthetic heart valves in pregnancy, outcomes for women and their babies: A systematic review and meta-analysis. BJOG, 122(11), 1446-1455. [More Information]
  • Lain, S., Roberts, C., Wilcken, B., Wiley, V., Jack, M., Nassar, N. (2015). Using record linkage to investigate perinatal factors and neonatal thyroid-stimulating hormone. Journal of Paediatrics and Child Health, 51(6), 620-625. [More Information]
  • Lawley, C., Lain, S., Algert, C., Ford, J., Figtree, G., Roberts, C. (2014). Prosthetic heart valves in pregnancy: a systematic review and meta-analysis protocol. Systematic Reviews, 3, 1-7. [More Information]
  • Lain, S., Roberts, C., Bowen, J., Nassar, N. (2014). Trends in New South Wales infant hospital readmission rates in the first year of life: A population-based study. Medical Journal of Australia, 201(1), 40-43. [More Information]
  • Lain, S., Nassar, N., Bowen, J., Roberts, C. (2013). Risk Factors and Costs of Hospital Admissions in First Year of Life: A Population-Based Study. The Journal of Pediatrics, 163(4), 1014-1019. [More Information]
  • Lain, S., Algert, C., Nassar, N., Bowen, J., Roberts, C. (2012). Incidence of Severe Adverse Neonatal Outcomes: Use of a Composite Indicator in a Population Cohort. Maternal and Child Health Journal, 16(3), 600-608. [More Information]
  • Lain, S., Hadfield, R., Raynes-Greenow, C., Ford, J., Mealing, N., Algert, C., Roberts, C. (2012). Quality of Data in Perinatal Population Health Databases: A Systematic Review. Medical Care, 50(4), e7-e20. [More Information]
  • Lain, S., Roberts, C., Warning, J., Vivian-Taylor, J., Ford, J. (2011). A survey of acute self-reported infections in pregnancy. BMJ Open, 1(1), 1-6. [More Information]
  • Algert, C., Bowen, J., Lain, S., Allen, H., Vivian-Taylor, J., Roberts, C. (2011). Pregnancy exposures and risk of childhood asthma admission in a population birth cohort. Pediatric Allergy and Immunology, 22(8), 836-842. [More Information]
  • Lain, S., Ford, J., Hadfield, R., Roberts, C. (2010). A prevalence survey of every-day activities in pregnancy. BMC Pregnancy and Childbirth, 10(41), 41-1-41-5. [More Information]
  • Lain, S., Roberts, C., Raynes-Greenow, C., Morris, J. (2010). The impact of the baby bonus on maternity services in New South Wales. Australian and New Zealand Journal of Obstetrics and Gynaecology, 50(1), 25-29. [More Information]
  • Hadfield, R., Lain, S., Simpson, J., Ford, J., Raynes-Greenow, C., Morris, J., Roberts, C. (2009). Are babies getting bigger? An analysis of birthweight trends in New South Wales, 1990-2005. Medical Journal of Australia, 190(6), 312-315. [More Information]
  • Hadfield, R., Lain, S., Raynes-Greenow, C., Morris, J., Roberts, C. (2009). Is there an association between endometriosis and the risk of pre-eclampsia? A population based study. Human Reproduction, 24(9), 2348-2352. [More Information]
  • Lain, S., Algert, C., Tasevski, V., Morris, J., Roberts, C. (2009). Record linkage to obtain birth outcomes for the evaluation of screening biomarkers in pregnancy: a feasibility study. BMC Medical Research Methodology, 9(1), 48-1-48-7. [More Information]
  • Algert, C., Bowen, J., Giles, W., Knoblanche, G., Lain, S., Roberts, C. (2009). Regional block versus general anaesthesia for caesarean section and neonatal outcomes: a population-based study. BMC Medicine, 7, 20-1-20-7. [More Information]
  • Lain, S., Ford, J., Raynes-Greenow, C., Hadfield, R., Simpson, J., Morris, J., Roberts, C. (2009). The impact of the Baby Bonus payment in New South Wales: who is having "one for the country"? Medical Journal of Australia, 190(5), 238-241. [More Information]
  • Lain, S., Roberts, C., Hadfield, R., Bell, J., Morris, J. (2008). How accurate is the reporting of obstetric haemorrhage in hospital discharge data? A validation study. Australian and New Zealand Journal of Obstetrics and Gynaecology, 48(5), 481-484. [More Information]
  • Roberts, C., Ford, J., Lain, S., Algert, C., Sparks, C. (2008). The accuracy of reporting of general anaesthesia for childbirth: a validation study. Anaesthesia and Intensive Care, 36(3), 418-424. [More Information]
  • Hadfield, R., Lain, S., Cameron, C., Bell, J., Morris, J., Roberts, C. (2008). The prevalence of maternal medical conditions during pregnancy and a validation of their reporting in hospital discharge data. Australian and New Zealand Journal of Obstetrics and Gynaecology, 48(1), 78-82. [More Information]
  • Lain, S., Ford, J., Hadfield, R., Blyth, F., Giles, W., Roberts, C. (2008). Trends in the use of epidural analgesia in Australia. International Journal of Gynecology and Obstetrics, 102(3), 253-258. [More Information]
  • Roberts, C., Lain, S., Morris, J. (2008). Variation in adherence to recommendations for management of the third stage of labor. International Journal of Gynecology and Obstetrics, 103(2), 172-173. [More Information]
  • Roberts, C., Lain, S., Morris, J. (2008). Variation in adherence to recommendations for management of the third stage of labor. International Journal of Gynecology and Obstetrics, 103(2), 172-3. [More Information]
  • Roberts, C., Lain, S., Hadfield, R. (2007). Quality of population health data reporting by mode of delivery. Birth: Issues in Perinatal Care, 34(3), 274-275. [More Information]

2018

  • Bentley, J., Schneuer, F., Lain, S., Martin, A., Gordon, A., Nassar, N. (2018). Neonatal morbidity at term, early child development, and school performance: A population study. Pediatrics, 141(2). [More Information]
  • Schneuer, F., Bentley, J., Davidson, A., Holland, A., Badawi, N., Martin, A., Skowno, J., Lain, S., Nassar, N. (2018). Reply to Ritchie-McLean, Susanna; Wilmshurst, Sally, regarding their comment "Can population cohort studies assess the long?term impact of anaesthesia in children?". Paediatric Anaesthesia, 28(12), 1157-1158. [More Information]
  • Schneuer, F., Bentley, J., Davidson, A., Holland, A., Badawi, N., Martin, A., Skowno, J., Lain, S., Nassar, N. (2018). The impact of general anesthesia on child development and school performance: a population-based study. Paediatric Anaesthesia, 28(6), 528-536. [More Information]

2017

  • Lain, S., Roberts, C., Bond, D., Smith, J., Morris, J. (2017). An economic evaluation of planned immediate versus delayed birth for preterm prelabour rupture of membranes: findings from the PPROMT randomised controlled trial. BJOG, 124(4), 623-630. [More Information]
  • Lain, S., Trumpff, C., Grosse, S., Olivieri, A., Van�Vlie, G. (2017). Are lower TSH cutoffs in neonatal screening for congenital hypothyroidism warranted? European Journal of Endocrinology, 177(5), D1-D12. [More Information]
  • Schneuer, F., Bentley, J., Holland, A., Lain, S., Jamieson, S., Badawi, N., Nassar, N. (2017). Early Childhood Development of Boys with Genital Anomalies. Birth Defects Research, 109(8), 535-542. [More Information]
  • Lawley, C., Lain, S., Figtree, G., Sholler, G., Winlaw, D., Roberts, C. (2017). Mortality, rehospitalizations and costs in children undergoing a cardiac procedure in their first year of life in New South Wales, Australia. International Journal of Cardiology, 241, 156-162. [More Information]

2016

  • Lain, S., Bentley, J., Wiley, V., Roberts, C., Jack, M., Wilcken, B., Nassar, N. (2016). Association between borderline neonatal thyroid-stimulating hormone concentrations and educational and developmental outcomes: a population-based record-linkage study. The Lancet Diabetes & Endocrinology, 4(9), 756-765. [More Information]
  • Stephens, A., Lain, S., Roberts, C., Bowen, J., Nassar, N. (2016). Association of Gestational Age and Severe Neonatal Morbidity with Mortality in Early Childhood. Paediatric and Perinatal Epidemiology, 30(6), 583-593. [More Information]
  • Lawley, C., Lain, S., Figtree, G., Roberts, C. (2016). Health outcomes of infants born to women with heart valve prostheses: complications of prematurity alone? The Journal of Maternal-Fetal and Neonatal Medicine, 29(2), 234-236. [More Information]
  • Stephens, A., Lain, S., Roberts, C., Bowen, J., Nassar, N. (2016). Survival, Hospitalization, and Acute-Care Costs of Very and Moderate Preterm Infants in the First 6 Years of Life: A Population-Based Study. The Journal of Pediatrics, 169, 61-68.e3. [More Information]

2015

  • Lain, S., Roberts, C., Bowen, J., Nassar, N. (2015). Early discharge of infants and risk of readmission for jaundice. Pediatrics, 135(2), 314-321. [More Information]
  • Stephens, A., Lain, S., Roberts, C., Bowen, J., Simpson, A., Nassar, N. (2015). Hospitalisations from 1 to 6 Years of Age: Effects of Gestational Age and Severe Neonatal Morbidity. Paediatric and Perinatal Epidemiology, 29(3), 241-249. [More Information]
  • Lawley, C., Lain, S., Algert, C., Ford, J., Figtree, G., Roberts, C. (2015). Prosthetic heart valves in pregnancy, outcomes for women and their babies: A systematic review and meta-analysis. BJOG, 122(11), 1446-1455. [More Information]
  • Lain, S., Roberts, C., Wilcken, B., Wiley, V., Jack, M., Nassar, N. (2015). Using record linkage to investigate perinatal factors and neonatal thyroid-stimulating hormone. Journal of Paediatrics and Child Health, 51(6), 620-625. [More Information]

2014

  • Lawley, C., Lain, S., Algert, C., Ford, J., Figtree, G., Roberts, C. (2014). Prosthetic heart valves in pregnancy: a systematic review and meta-analysis protocol. Systematic Reviews, 3, 1-7. [More Information]
  • Lain, S., Roberts, C., Bowen, J., Nassar, N. (2014). Trends in New South Wales infant hospital readmission rates in the first year of life: A population-based study. Medical Journal of Australia, 201(1), 40-43. [More Information]

2013

  • Lain, S., Nassar, N., Bowen, J., Roberts, C. (2013). Risk Factors and Costs of Hospital Admissions in First Year of Life: A Population-Based Study. The Journal of Pediatrics, 163(4), 1014-1019. [More Information]

2012

  • Lain, S., Algert, C., Nassar, N., Bowen, J., Roberts, C. (2012). Incidence of Severe Adverse Neonatal Outcomes: Use of a Composite Indicator in a Population Cohort. Maternal and Child Health Journal, 16(3), 600-608. [More Information]
  • Lain, S., Hadfield, R., Raynes-Greenow, C., Ford, J., Mealing, N., Algert, C., Roberts, C. (2012). Quality of Data in Perinatal Population Health Databases: A Systematic Review. Medical Care, 50(4), e7-e20. [More Information]

2011

  • Lain, S., Roberts, C., Warning, J., Vivian-Taylor, J., Ford, J. (2011). A survey of acute self-reported infections in pregnancy. BMJ Open, 1(1), 1-6. [More Information]
  • Algert, C., Bowen, J., Lain, S., Allen, H., Vivian-Taylor, J., Roberts, C. (2011). Pregnancy exposures and risk of childhood asthma admission in a population birth cohort. Pediatric Allergy and Immunology, 22(8), 836-842. [More Information]

2010

  • Lain, S., Ford, J., Hadfield, R., Roberts, C. (2010). A prevalence survey of every-day activities in pregnancy. BMC Pregnancy and Childbirth, 10(41), 41-1-41-5. [More Information]
  • Lain, S., Roberts, C., Raynes-Greenow, C., Morris, J. (2010). The impact of the baby bonus on maternity services in New South Wales. Australian and New Zealand Journal of Obstetrics and Gynaecology, 50(1), 25-29. [More Information]

2009

  • Hadfield, R., Lain, S., Simpson, J., Ford, J., Raynes-Greenow, C., Morris, J., Roberts, C. (2009). Are babies getting bigger? An analysis of birthweight trends in New South Wales, 1990-2005. Medical Journal of Australia, 190(6), 312-315. [More Information]
  • Hadfield, R., Lain, S., Raynes-Greenow, C., Morris, J., Roberts, C. (2009). Is there an association between endometriosis and the risk of pre-eclampsia? A population based study. Human Reproduction, 24(9), 2348-2352. [More Information]
  • Lain, S., Algert, C., Tasevski, V., Morris, J., Roberts, C. (2009). Record linkage to obtain birth outcomes for the evaluation of screening biomarkers in pregnancy: a feasibility study. BMC Medical Research Methodology, 9(1), 48-1-48-7. [More Information]
  • Algert, C., Bowen, J., Giles, W., Knoblanche, G., Lain, S., Roberts, C. (2009). Regional block versus general anaesthesia for caesarean section and neonatal outcomes: a population-based study. BMC Medicine, 7, 20-1-20-7. [More Information]
  • Lain, S., Ford, J., Raynes-Greenow, C., Hadfield, R., Simpson, J., Morris, J., Roberts, C. (2009). The impact of the Baby Bonus payment in New South Wales: who is having "one for the country"? Medical Journal of Australia, 190(5), 238-241. [More Information]

2008

  • Lain, S., Roberts, C., Hadfield, R., Bell, J., Morris, J. (2008). How accurate is the reporting of obstetric haemorrhage in hospital discharge data? A validation study. Australian and New Zealand Journal of Obstetrics and Gynaecology, 48(5), 481-484. [More Information]
  • Roberts, C., Ford, J., Lain, S., Algert, C., Sparks, C. (2008). The accuracy of reporting of general anaesthesia for childbirth: a validation study. Anaesthesia and Intensive Care, 36(3), 418-424. [More Information]
  • Hadfield, R., Lain, S., Cameron, C., Bell, J., Morris, J., Roberts, C. (2008). The prevalence of maternal medical conditions during pregnancy and a validation of their reporting in hospital discharge data. Australian and New Zealand Journal of Obstetrics and Gynaecology, 48(1), 78-82. [More Information]
  • Lain, S., Ford, J., Hadfield, R., Blyth, F., Giles, W., Roberts, C. (2008). Trends in the use of epidural analgesia in Australia. International Journal of Gynecology and Obstetrics, 102(3), 253-258. [More Information]
  • Roberts, C., Lain, S., Morris, J. (2008). Variation in adherence to recommendations for management of the third stage of labor. International Journal of Gynecology and Obstetrics, 103(2), 172-173. [More Information]
  • Roberts, C., Lain, S., Morris, J. (2008). Variation in adherence to recommendations for management of the third stage of labor. International Journal of Gynecology and Obstetrics, 103(2), 172-3. [More Information]

2007

  • Roberts, C., Lain, S., Hadfield, R. (2007). Quality of population health data reporting by mode of delivery. Birth: Issues in Perinatal Care, 34(3), 274-275. [More Information]
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