Dr Serigne Lo

Senior Research Fellow - Melanoma Institute Australia

Telephone + 61 2 9911 7338
Fax + 61 2 9954 9435

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Biographical details

Serigne is a Senior Research Fellow in Biostatistics at the Melanoma Institute Australia where he manage the Research and Biostatistics Group. He has 14 years of experience including 6 years of undergraduate/postgraduate teaching at the University of Geneva and 8 years as biostatistician at the George Institute for Global Health – Australia.

Serigne has a strong background in quantitative analysis. He holds a Master in Econometrics (2002) and a PhD in Statistics/Econometrics (2006) from the University of Geneva.

Research interests

Serigne's research interests are broadly in the area of Randomised Clinical trial, Adaptive Design, Advanced Survival analysis, Cluster randomised trial, Multistate modelling, Joint-modelling, Multilevel modelling, Stepped Wedge design and Robust statistics.

Teaching and supervision

Biostatistics

Selected grants

2015

  • An integrated general practice and pharmacy-based intervention to promote the prescription and use of appropriate preventive medications among individuals at high cardiovascular risk.; Patel A, Peiris D, Saini B, Joshi R, Usherwood T, Armour C, Webster R, Lo S; National Health and Medical Research Council (NHMRC)/Project Grants.

2014

  • Burn injuries in Aboriginal and Torres Strait Islander children; Ivers R, Holland A, Kimble R, Clapham K, Lo S, Daniels J, Hendrie D; National Health and Medical Research Council (NHMRC)/Project Grants.

Selected publications

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Journals

  • Gleeson, M., Sherrington, C., Lo, S., Keay, L. (2015). Can the Alexander Technique improve balance and mobility in older adults with visual impairments? A randomized controlled trial. Clinical Rehabilitation, 29(3), 244-260. [More Information]
  • Dinh, M., Bein, K., Gabbe, B., Byrne, C., Petchell, J., Lo, S., Ivers, R. (2014). A trauma quality improvement programme associated with improved patient outcomes: 21 years of experience at an Australian Major Trauma Centre. Injury, 45(5), 830-834. [More Information]
  • Laba, T., Hayes, A., Lo, S., Peiris, D., Usherwood, T., Hillis, G., Rafter, N., Reid, C., Tonkin, A., Webster, R., Neal, B., Patel, A., Rodgers, A., Jan, S., et al (2014). An economic case for a cardiovascular polypill? A cost analysis of the Kanyini GAP trial. Medical Journal of Australia, 201(11), 671-673. [More Information]
  • Wang, A., Bellomo, R., Ninomiya, T., Lo, S., Cass, A., Jardine, M., Gallagher, M. (2014). Angiotensin converting enzyme inhibitor usage and acute kidney injury: a secondary analysis of RENAL study outcomes. Nephrology, 19(10), 617-622. [More Information]
  • Bellomo, R., Cass, A., Cole, L., Finfer, S., Gallagher, M., Lee, J., Lo, S., McArthur, C., McGuinness, S., Myburgh, J., Norton, R., et al (2014). Calorie intake and patient outcomes in severe acute kidney injury: findings from The Randomized Evaluation of Normal vs. Augmented Level of Replacement Therapy (RENAL) study trial. Critical Care, 18(2), 1-11. [More Information]
  • Bellomo, R., Cass, A., Cole, L., Finfer, S., Gallagher, M., Lee, J., Lo, S., McArthur, C., McGuinness, S., Norton, R., Myburgh, J., et al (2014). Daily protein intake and patient outcomes in severe acute kidney injury: findings of the randomized evaluation of normal versus augmented level of replacement therapy (RENAL) trial. Blood Purification, 37(4), 325-334. [More Information]
  • Keay, L., Palagyi, A., McCluskey, P., Lamoureux, E., Pesudovs, K., Lo, S., Ivers, R., Boufous, S., Morlet, N., Ng, J., et al (2014). Falls in Older people with Cataract, a longitudinal evaluation of impact and risk: the FOCUS study protocol. Injury Prevention, 20(4), 1-6.
  • Du, X., Gao, R., Turnbull, F., Wu, Y., Rong, Y., Lo, S., Billot, L., Hao, Z., Ranasinghe, I., Iedema, R., Patel, A., et al (2014). Hospital quality improvement initiative for patients with acute coronary syndromes in China: a cluster randomized, controlled trial. Circulation. Cardiovascular Quality and Outcomes, 7(2), 217-226. [More Information]
  • Gallagher, M., Cass, A., Bellomo, R., Finfer, S., Gattas, D., Lee, J., Lo, S., McGuinness, S., Myburgh, J., Parke, R., et al (2014). Long-term survival and dialysis dependency following acute kidney injury in intensive care: Extended follow-up of a randomized controlled trial. PLoS Medicine, 11(2), 1-13. [More Information]
  • Ma, J., Heritier, S., Lo, S. (2014). On the maximum penalized likelihood approach for proportional hazard models with right censored survival data. Computational Statistics and Data Analysis, 74, 142-156. [More Information]
  • Sakashita, C., Jan, S., Senserrick, T., Lo, S., Ivers, R. (2014). Perceived value of a motorcycle training program: the influence of crash history and experience of the training. Traffic Injury Prevention, 15(4), 407-413. [More Information]
  • Alsaadi, S., McAuley, J., Hush, J., Lo, S., Lin, C., Williams, C., Maher, C. (2014). Poor sleep quality is strongly associated with subsequent pain intensity in patients with acute low back pain. Arthritis & Rheumatology, 66(5), 1388-1394. [More Information]
  • Hudson, H., Lo, S., Simes, R., Tonkin, A., Heritier, S. (2014). Semiparametric methods for multistate survival models in randomised trials. Statistics in Medicine, 33, 1621-1645. [More Information]
  • Alsaadi, S., McAuley, J., Hush, J., Lo, S., Bartlett, D., Grunstein, R., Maher, C. (2014). The Bidirectional Relationship Between Pain Intensity and Sleep Disturbance/Quality in Patients with Low Back Pain. Clinical Journal of Pain, 30(9), 755-765. [More Information]
  • Sakashita, C., Senserrick, T., Lo, S., Boufous, S., de Rome, L., Ivers, R. (2014). The Motorcycle Rider Behavior Questionnaire: Psychometric properties and application amongst novice riders in Australia. Transportation Research Part F, 22, 126-139. [More Information]
  • Bellomo, R., Cass, A., Cole, L., Finfer, S., Gallagher, M., Kim, I., Lee, J., Lo, S., McArthur, C., McGuinness, S., Norton, R., Myburgh, J., et al (2014). The relationship between hypophosphataemia and outcomes during low-intensity and high-intensity continuous renal replacement therapy. Critical Care and Resuscitation, 16(1), 34-41.
  • Jun, M., Bellomo, R., Cass, A., Gallagher, M., Lo, S., Lee, J. (2014). Timing of Renal Replacement Therapy and Patient Outcomes in the Randomized Evaluation of Normal Versus Augmented Level of Replacement Therapy Study. Critical Care Medicine, 42(8), 1756-1765. [More Information]
  • Keay, L., Coxon, K., Brown, J., Clarke, E., Bundy, A., Ivers, R., Lo, S., Boufous, S. (2013). A randomized trial to evaluate the effectiveness of an individual, education-based safe transport program for drivers aged 75 years and older. BMC Public Health, 13, 1-8. [More Information]
  • Schneider, A., Bellomo, R., Bagshaw, S., Glassford, N., Lo, S., Jun, M., Cass, A., Gallagher, M. (2013). Choice of renal replacement therapy modality and dialysis dependence after acute kidney injury: a systematic review and meta-analysis. Intensive Care Medicine, 39(6), 987-997. [More Information]
  • Bellomo, R., Lipcsey, M., Calzavacca, P., Haase, M., Haase-Fielitz, A., Licari, E., Tee, A., Cole, L., Cass, A., Finfer, S., Gallagher, M., Myburgh, J., et al (2013). Early acid-base and blood pressure effects of continuous renal replacement therapy intensity in patients with metabolic acidosis. Intensive Care Medicine, 39(3), 429-436. [More Information]
  • Gattas, D., Dan, A., Myburgh, J., Billot, L., Lo, S., Finfer, S. (2013). Fluid resuscitation with 6% hydroxyethyl starch (130/0.4 and 130/0.42) in acutely ill patients: systematic review of effects on mortality and treatment with renal replacement therapy. Intensive Care Medicine, 39(4), 558-568. [More Information]
  • Martiniuk, A., Senserrick, T., Lo, S., Williamson, A., Du, W., Grunstein, R., Woodward, M., Glozier, N., Stevenson, M., Norton, R., Ivers, R. (2013). Sleep-Deprived Young Drivers and the Risk for Crash: The DRIVE Prospective Cohort Study. JAMA Pediatrics, 167(7), 647-655. [More Information]
  • Pascoe, E., Lo, S., Scaria, A., Badve, S., Beller, E., Cass, A., Hawley, C., Johnson, D. (2013). The HONEYPOT randomized controlled trial statistical analysis plan. Peritoneal Dialysis International, 33(4), 426-435. [More Information]
  • Bellomo, R., Cass, A., Cole, L., Finfer, S., Gallagher, M., Lee, J., Lo, S., McArthur, C., McGuiness, S., Norton, R., et al (2012). An observational study fluid balance and patient outcomes in the randomized evaluation of normal vs. augmented level of replacement therapy trial. Critical Care Medicine, 40(6), 1753-1760. [More Information]
  • Asha, S., Curtis, K., Grant, N., Taylor, C., Lo, S., Smart, R., Compagnoni, K. (2012). Comparison of radiation exposure of trauma patients from diagnostic radiology procedures before and after the introduction of a panscan protocol. Emergency Medicine Australasia, 24(1), 43-51. [More Information]
  • Gattas, D., Dan, A., Myburgh, J., Billot, L., Lo, S., Finfer, S. (2012). Fluid resuscitation with 6% hydroxyethyl starch (130/0.4) in acutely ill patients: an updated systematic review and meta-analysis. Anesthesia and Analgesia, 114(1), 159-169. [More Information]
  • Lo, S., Ronchetti, E. (2012). Robust small sample accurate inference in moment condition models. Computational Statistics and Data Analysis, 56(11), 3182-3197. [More Information]
  • Wong, G., Zoungas, S., Lo, S., Chalmers, J., Cass, A., Neal, B., Woodward, M., Perkovic, V., Glasziou, P., Williams, B., Howard, K., Chapman, J., Craig, J. (2012). The risk of cancer in people with diabetes and chronic kidney disease. Nephrology, Dialysis, Transplantation, 27(8), 3337-3344. [More Information]
  • Heritier, S., Lo, S., Morgan, C. (2011). An adaptive confirmatory trial with interim treatment selection: Practical experiences and unbalanced randomization. Statistics in Medicine, 30(13), 1541-1554. [More Information]
  • Bellomo, R., Cass, A., Norton, R., Gallagher, M., Lo, S., Su, S., Cole, C., Finfer, S., McArthur, C., McGuinness, S., Myburgh, J., et al (2009). Intensity of continuous renal-replacement therapy in critically ill patients. New England Journal of Medicine, 361(17), 1627-1638. [More Information]
  • Lo, S., Heritier, S., Hudson, M. (2009). Saddlepoint approximation for semi-Markov processes with application to a cardiovascular randomised study. Computational Statistics and Data Analysis, 53(3), 683-698. [More Information]

2015

  • Gleeson, M., Sherrington, C., Lo, S., Keay, L. (2015). Can the Alexander Technique improve balance and mobility in older adults with visual impairments? A randomized controlled trial. Clinical Rehabilitation, 29(3), 244-260. [More Information]

2014

  • Dinh, M., Bein, K., Gabbe, B., Byrne, C., Petchell, J., Lo, S., Ivers, R. (2014). A trauma quality improvement programme associated with improved patient outcomes: 21 years of experience at an Australian Major Trauma Centre. Injury, 45(5), 830-834. [More Information]
  • Laba, T., Hayes, A., Lo, S., Peiris, D., Usherwood, T., Hillis, G., Rafter, N., Reid, C., Tonkin, A., Webster, R., Neal, B., Patel, A., Rodgers, A., Jan, S., et al (2014). An economic case for a cardiovascular polypill? A cost analysis of the Kanyini GAP trial. Medical Journal of Australia, 201(11), 671-673. [More Information]
  • Wang, A., Bellomo, R., Ninomiya, T., Lo, S., Cass, A., Jardine, M., Gallagher, M. (2014). Angiotensin converting enzyme inhibitor usage and acute kidney injury: a secondary analysis of RENAL study outcomes. Nephrology, 19(10), 617-622. [More Information]
  • Bellomo, R., Cass, A., Cole, L., Finfer, S., Gallagher, M., Lee, J., Lo, S., McArthur, C., McGuinness, S., Myburgh, J., Norton, R., et al (2014). Calorie intake and patient outcomes in severe acute kidney injury: findings from The Randomized Evaluation of Normal vs. Augmented Level of Replacement Therapy (RENAL) study trial. Critical Care, 18(2), 1-11. [More Information]
  • Bellomo, R., Cass, A., Cole, L., Finfer, S., Gallagher, M., Lee, J., Lo, S., McArthur, C., McGuinness, S., Norton, R., Myburgh, J., et al (2014). Daily protein intake and patient outcomes in severe acute kidney injury: findings of the randomized evaluation of normal versus augmented level of replacement therapy (RENAL) trial. Blood Purification, 37(4), 325-334. [More Information]
  • Keay, L., Palagyi, A., McCluskey, P., Lamoureux, E., Pesudovs, K., Lo, S., Ivers, R., Boufous, S., Morlet, N., Ng, J., et al (2014). Falls in Older people with Cataract, a longitudinal evaluation of impact and risk: the FOCUS study protocol. Injury Prevention, 20(4), 1-6.
  • Du, X., Gao, R., Turnbull, F., Wu, Y., Rong, Y., Lo, S., Billot, L., Hao, Z., Ranasinghe, I., Iedema, R., Patel, A., et al (2014). Hospital quality improvement initiative for patients with acute coronary syndromes in China: a cluster randomized, controlled trial. Circulation. Cardiovascular Quality and Outcomes, 7(2), 217-226. [More Information]
  • Gallagher, M., Cass, A., Bellomo, R., Finfer, S., Gattas, D., Lee, J., Lo, S., McGuinness, S., Myburgh, J., Parke, R., et al (2014). Long-term survival and dialysis dependency following acute kidney injury in intensive care: Extended follow-up of a randomized controlled trial. PLoS Medicine, 11(2), 1-13. [More Information]
  • Ma, J., Heritier, S., Lo, S. (2014). On the maximum penalized likelihood approach for proportional hazard models with right censored survival data. Computational Statistics and Data Analysis, 74, 142-156. [More Information]
  • Sakashita, C., Jan, S., Senserrick, T., Lo, S., Ivers, R. (2014). Perceived value of a motorcycle training program: the influence of crash history and experience of the training. Traffic Injury Prevention, 15(4), 407-413. [More Information]
  • Alsaadi, S., McAuley, J., Hush, J., Lo, S., Lin, C., Williams, C., Maher, C. (2014). Poor sleep quality is strongly associated with subsequent pain intensity in patients with acute low back pain. Arthritis & Rheumatology, 66(5), 1388-1394. [More Information]
  • Hudson, H., Lo, S., Simes, R., Tonkin, A., Heritier, S. (2014). Semiparametric methods for multistate survival models in randomised trials. Statistics in Medicine, 33, 1621-1645. [More Information]
  • Alsaadi, S., McAuley, J., Hush, J., Lo, S., Bartlett, D., Grunstein, R., Maher, C. (2014). The Bidirectional Relationship Between Pain Intensity and Sleep Disturbance/Quality in Patients with Low Back Pain. Clinical Journal of Pain, 30(9), 755-765. [More Information]
  • Sakashita, C., Senserrick, T., Lo, S., Boufous, S., de Rome, L., Ivers, R. (2014). The Motorcycle Rider Behavior Questionnaire: Psychometric properties and application amongst novice riders in Australia. Transportation Research Part F, 22, 126-139. [More Information]
  • Bellomo, R., Cass, A., Cole, L., Finfer, S., Gallagher, M., Kim, I., Lee, J., Lo, S., McArthur, C., McGuinness, S., Norton, R., Myburgh, J., et al (2014). The relationship between hypophosphataemia and outcomes during low-intensity and high-intensity continuous renal replacement therapy. Critical Care and Resuscitation, 16(1), 34-41.
  • Jun, M., Bellomo, R., Cass, A., Gallagher, M., Lo, S., Lee, J. (2014). Timing of Renal Replacement Therapy and Patient Outcomes in the Randomized Evaluation of Normal Versus Augmented Level of Replacement Therapy Study. Critical Care Medicine, 42(8), 1756-1765. [More Information]

2013

  • Keay, L., Coxon, K., Brown, J., Clarke, E., Bundy, A., Ivers, R., Lo, S., Boufous, S. (2013). A randomized trial to evaluate the effectiveness of an individual, education-based safe transport program for drivers aged 75 years and older. BMC Public Health, 13, 1-8. [More Information]
  • Schneider, A., Bellomo, R., Bagshaw, S., Glassford, N., Lo, S., Jun, M., Cass, A., Gallagher, M. (2013). Choice of renal replacement therapy modality and dialysis dependence after acute kidney injury: a systematic review and meta-analysis. Intensive Care Medicine, 39(6), 987-997. [More Information]
  • Bellomo, R., Lipcsey, M., Calzavacca, P., Haase, M., Haase-Fielitz, A., Licari, E., Tee, A., Cole, L., Cass, A., Finfer, S., Gallagher, M., Myburgh, J., et al (2013). Early acid-base and blood pressure effects of continuous renal replacement therapy intensity in patients with metabolic acidosis. Intensive Care Medicine, 39(3), 429-436. [More Information]
  • Gattas, D., Dan, A., Myburgh, J., Billot, L., Lo, S., Finfer, S. (2013). Fluid resuscitation with 6% hydroxyethyl starch (130/0.4 and 130/0.42) in acutely ill patients: systematic review of effects on mortality and treatment with renal replacement therapy. Intensive Care Medicine, 39(4), 558-568. [More Information]
  • Martiniuk, A., Senserrick, T., Lo, S., Williamson, A., Du, W., Grunstein, R., Woodward, M., Glozier, N., Stevenson, M., Norton, R., Ivers, R. (2013). Sleep-Deprived Young Drivers and the Risk for Crash: The DRIVE Prospective Cohort Study. JAMA Pediatrics, 167(7), 647-655. [More Information]
  • Pascoe, E., Lo, S., Scaria, A., Badve, S., Beller, E., Cass, A., Hawley, C., Johnson, D. (2013). The HONEYPOT randomized controlled trial statistical analysis plan. Peritoneal Dialysis International, 33(4), 426-435. [More Information]

2012

  • Bellomo, R., Cass, A., Cole, L., Finfer, S., Gallagher, M., Lee, J., Lo, S., McArthur, C., McGuiness, S., Norton, R., et al (2012). An observational study fluid balance and patient outcomes in the randomized evaluation of normal vs. augmented level of replacement therapy trial. Critical Care Medicine, 40(6), 1753-1760. [More Information]
  • Asha, S., Curtis, K., Grant, N., Taylor, C., Lo, S., Smart, R., Compagnoni, K. (2012). Comparison of radiation exposure of trauma patients from diagnostic radiology procedures before and after the introduction of a panscan protocol. Emergency Medicine Australasia, 24(1), 43-51. [More Information]
  • Gattas, D., Dan, A., Myburgh, J., Billot, L., Lo, S., Finfer, S. (2012). Fluid resuscitation with 6% hydroxyethyl starch (130/0.4) in acutely ill patients: an updated systematic review and meta-analysis. Anesthesia and Analgesia, 114(1), 159-169. [More Information]
  • Lo, S., Ronchetti, E. (2012). Robust small sample accurate inference in moment condition models. Computational Statistics and Data Analysis, 56(11), 3182-3197. [More Information]
  • Wong, G., Zoungas, S., Lo, S., Chalmers, J., Cass, A., Neal, B., Woodward, M., Perkovic, V., Glasziou, P., Williams, B., Howard, K., Chapman, J., Craig, J. (2012). The risk of cancer in people with diabetes and chronic kidney disease. Nephrology, Dialysis, Transplantation, 27(8), 3337-3344. [More Information]

2011

  • Heritier, S., Lo, S., Morgan, C. (2011). An adaptive confirmatory trial with interim treatment selection: Practical experiences and unbalanced randomization. Statistics in Medicine, 30(13), 1541-1554. [More Information]

2009

  • Bellomo, R., Cass, A., Norton, R., Gallagher, M., Lo, S., Su, S., Cole, C., Finfer, S., McArthur, C., McGuinness, S., Myburgh, J., et al (2009). Intensity of continuous renal-replacement therapy in critically ill patients. New England Journal of Medicine, 361(17), 1627-1638. [More Information]
  • Lo, S., Heritier, S., Hudson, M. (2009). Saddlepoint approximation for semi-Markov processes with application to a cardiovascular randomised study. Computational Statistics and Data Analysis, 53(3), 683-698. [More Information]

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