Dr Sharon McCracken

Senior Research Fellow
Kolling Institute of Medical Research


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Current research students

Project title Research student
Working towards a new therapy for the prevention of impaired fetal growth. Gaayathri ARIYAKUMAR

Selected grants

2014

  • Working towards a new therapy for IUGR; Morris J, McCracken S, Ashton A; National Health and Medical Research Council (NHMRC)/Project Grants.

2005

  • Multifunction Imaging System; Firth S, McCracken S, Marsh D, Chen X; University of Sydney/Research Support.

Selected publications

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Journals

  • Lappas, M., McCracken, S., McKelvey, K., Lim, R., James, J., Roberts, C., Fournier, T., Alfaidy, N., Powell, K., Borg, A., Morris, J., et al (2018). Formyl peptide receptor-2 is decreased in fetal growth restriction and contributes to placental dysfunction. Molecular Human Reproduction, 24(2), 94-109. [More Information]
  • McKelvey, K., Ariyakumar, G., McCracken, S. (2018). Inflammatory and immune system markers. Methods in Molecular Biology, 1710, 85-101. [More Information]
  • McCracken, S. (2018). Pregnancy � do we really understand how the immune system tolerates us? BJOG, 125(11), 1388-1388. [More Information]
  • McKelvey, K., Yenson, V., Ashton, A., Morris, J., McCracken, S. (2016). Embryonic/fetal mortality and intrauterine growth restriction is not exclusive to the CBA/J sub-strain in the CBA � DBA model. Scientific Reports, 6, 1-11. [More Information]
  • Powell, K., Stevens, V., Upton, D., McCracken, S., Simpson, A., Cheng, Y., Tasevski, V., Morris, J., Ashton, A. (2016). Role for the thromboxane A2 receptor (beta)-isoform in the pathogenesis of intrauterine growth restriction. Scientific Reports, 6, 1-15. [More Information]
  • McKelvey, K., Powell, K., Ashton, A., Morris, J., McCracken, S. (2015). Exosomes: Mechanisms of Uptake. Journal of Circulating Biomarkers, 4(7), 1-9. [More Information]
  • Jackson, M., Moradi, B., Zaki, S., Smith, M., McCracken, S., Smith, S., Jackson, C., Little, C. (2014). Depletion of protease-activated receptor 2 but not protease-activated receptor 1 may confer protection against osteoarthritis in mice through extracartilaginous mechanisms. Arthritis & Rheumatology, 66(12), 3337-3348. [More Information]
  • Warning, J., McCracken, S., Morris, J. (2011). A Balancing Act: Mechanisms By Which the Fetus Avoids Rejection By the Maternal Immune System. Reproduction, 141(6), 715-724. [More Information]
  • Hadfield, K., McCracken, S., Ashton, A., Nguyen, T., Morris, J. (2011). Regulated suppression of NF-kB throughout pregnancy maintains a favourable cytokine environment necessary for pregnancy success. Journal of Reproductive Immunology, 89(1), 1-9. [More Information]
  • Nguyen, T., Little, C., Yenson, V., Jackson, C., McCracken, S., Warning, J., Stevens, V., Gallery, E., Morris, J. (2010). Anti-IgD antibody attenuates collagen-induced arthritis by selectively depleting mature B-cells and promoting immune tolerance. Journal of Autoimmunity, 35(1), 86-97. [More Information]
  • McCracken, S., Hadfield, K., Rahimi, Z., Gallery, E., Morris, J. (2007). NF-kappaB-regulated suppression of T-bet in T cells represses Th1 immune responses in pregnancy. European Journal of Immunology, 37(5), 1386-1396. [More Information]
  • McCracken, S., Gallery, E., Morris, J. (2004). Pregnancy-Specific Down-Regulation Of Nf-Kappa B Expression In T Cells In Humans Is Essential For The Maintenance Of The Cytokine Profile Required For Pregnancy Success. Journal of Immunology, 172(7), 4583-4591.
  • Siva, S., Johnson, S., McCracken, S., Morris, J. (2003). Evaluation of the clinical usefulness of isolation of fetal DNA from the maternal circulation. Australian and New Zealand Journal of Obstetrics and Gynaecology, 43, 10-15. [More Information]
  • Robertson, S., Redman, C., McCracken, S., Hunt, J., Dimitriadise, E., Moffett-King, A., Chamley, L. (2003). Immune Modulators of Implantation and Placental Development - A Workshop Report. Placenta, 24(Suppl A), S16-S20. [More Information]
  • McCracken, S., Drury, C., Lee, H., Morris, J. (2003). Pregnancy is associated with suppression of the nuclear factor kappa B/I kappa B activation pathway in peripheral blood mononuclear cells. American Journal of Reproductive Immunology, 58(1), 27-47. [More Information]
  • Johnson, L., McCracken, S., Morris, J., Woodland, N., Flower, R. (2003). Variation in the reliability of RHD antenatal genotyping using the polymerase chain reaction and targeting multiple exons of the RHD gene. Vox Sanguinis, 85, 222-223. [More Information]

2018

  • Lappas, M., McCracken, S., McKelvey, K., Lim, R., James, J., Roberts, C., Fournier, T., Alfaidy, N., Powell, K., Borg, A., Morris, J., et al (2018). Formyl peptide receptor-2 is decreased in fetal growth restriction and contributes to placental dysfunction. Molecular Human Reproduction, 24(2), 94-109. [More Information]
  • McKelvey, K., Ariyakumar, G., McCracken, S. (2018). Inflammatory and immune system markers. Methods in Molecular Biology, 1710, 85-101. [More Information]
  • McCracken, S. (2018). Pregnancy � do we really understand how the immune system tolerates us? BJOG, 125(11), 1388-1388. [More Information]

2016

  • McKelvey, K., Yenson, V., Ashton, A., Morris, J., McCracken, S. (2016). Embryonic/fetal mortality and intrauterine growth restriction is not exclusive to the CBA/J sub-strain in the CBA � DBA model. Scientific Reports, 6, 1-11. [More Information]
  • Powell, K., Stevens, V., Upton, D., McCracken, S., Simpson, A., Cheng, Y., Tasevski, V., Morris, J., Ashton, A. (2016). Role for the thromboxane A2 receptor (beta)-isoform in the pathogenesis of intrauterine growth restriction. Scientific Reports, 6, 1-15. [More Information]

2015

  • McKelvey, K., Powell, K., Ashton, A., Morris, J., McCracken, S. (2015). Exosomes: Mechanisms of Uptake. Journal of Circulating Biomarkers, 4(7), 1-9. [More Information]

2014

  • Jackson, M., Moradi, B., Zaki, S., Smith, M., McCracken, S., Smith, S., Jackson, C., Little, C. (2014). Depletion of protease-activated receptor 2 but not protease-activated receptor 1 may confer protection against osteoarthritis in mice through extracartilaginous mechanisms. Arthritis & Rheumatology, 66(12), 3337-3348. [More Information]

2011

  • Warning, J., McCracken, S., Morris, J. (2011). A Balancing Act: Mechanisms By Which the Fetus Avoids Rejection By the Maternal Immune System. Reproduction, 141(6), 715-724. [More Information]
  • Hadfield, K., McCracken, S., Ashton, A., Nguyen, T., Morris, J. (2011). Regulated suppression of NF-kB throughout pregnancy maintains a favourable cytokine environment necessary for pregnancy success. Journal of Reproductive Immunology, 89(1), 1-9. [More Information]

2010

  • Nguyen, T., Little, C., Yenson, V., Jackson, C., McCracken, S., Warning, J., Stevens, V., Gallery, E., Morris, J. (2010). Anti-IgD antibody attenuates collagen-induced arthritis by selectively depleting mature B-cells and promoting immune tolerance. Journal of Autoimmunity, 35(1), 86-97. [More Information]

2007

  • McCracken, S., Hadfield, K., Rahimi, Z., Gallery, E., Morris, J. (2007). NF-kappaB-regulated suppression of T-bet in T cells represses Th1 immune responses in pregnancy. European Journal of Immunology, 37(5), 1386-1396. [More Information]

2004

  • McCracken, S., Gallery, E., Morris, J. (2004). Pregnancy-Specific Down-Regulation Of Nf-Kappa B Expression In T Cells In Humans Is Essential For The Maintenance Of The Cytokine Profile Required For Pregnancy Success. Journal of Immunology, 172(7), 4583-4591.

2003

  • Siva, S., Johnson, S., McCracken, S., Morris, J. (2003). Evaluation of the clinical usefulness of isolation of fetal DNA from the maternal circulation. Australian and New Zealand Journal of Obstetrics and Gynaecology, 43, 10-15. [More Information]
  • Robertson, S., Redman, C., McCracken, S., Hunt, J., Dimitriadise, E., Moffett-King, A., Chamley, L. (2003). Immune Modulators of Implantation and Placental Development - A Workshop Report. Placenta, 24(Suppl A), S16-S20. [More Information]
  • McCracken, S., Drury, C., Lee, H., Morris, J. (2003). Pregnancy is associated with suppression of the nuclear factor kappa B/I kappa B activation pathway in peripheral blood mononuclear cells. American Journal of Reproductive Immunology, 58(1), 27-47. [More Information]
  • Johnson, L., McCracken, S., Morris, J., Woodland, N., Flower, R. (2003). Variation in the reliability of RHD antenatal genotyping using the polymerase chain reaction and targeting multiple exons of the RHD gene. Vox Sanguinis, 85, 222-223. [More Information]

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