Dr Shounan Yi

Senior Research Fellow
Medicine, Westmead Clinical School
Westmead Millennium Institute for Medical Research

Telephone +61 2 9845 6877
Fax +61 2 9633 9351

Map

Selected grants

2014

  • Transplantation of pig islets to treat diabetes; Cowan P, Hawthorne W, Yi S, Nottle M; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Therapeutic potential of peritoneal mononuclear phagocytes from peritoneal dialysis patients; Wang Y, Harris D, Yi S; National Health and Medical Research Council (NHMRC)/Project Grants.

Selected publications

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Journals

  • Zhao, R., Tang, D., Yi, S., Li, W., Wu, C., Lu, Y., Hou, X., Song, J., Lin, P., Chen, L., et al (2014). Elevated peripheral frequencies of Th22 cells: a novel potent participant in obesity and type 2 diabetes. PLoS One, 9(1), 1-9. [More Information]
  • Jin, X., Wang, Y., Hawthorne, W., Hu, M., Yi, S., O'Connell, P. (2014). Enhanced Suppression of the Xenogeneic T-Cell Response in Vitro by Xenoantigen Stimulated and Expanded Regulatory T Cells. Transplantation, 97(1), 30-38. [More Information]
  • Hu, M., Wu, J., Zhang, G., Wang, Y., Watson, D., Yi, S., Hawthorne, W., O'Connell, P., Alexander, S. (2013). Selective Depletion of Alloreactive T cells Leads to Long-Term Islet Allograft Survival Across a Major Histocompatibility Complex Mismatch in Diabetic Mice. Cell Transplantation, 22(10), 1929-1941. [More Information]
  • O'Connell, P., Cowan, P., Hawthorne, W., Yi, S., Lew, A. (2013). Transplantation of Xenogeneic Islets: Are We There Yet? Current Diabetes Reports, 13(5), 687-694. [More Information]
  • Ji, M., Jin, X., Phillips, P., Yi, S. (2012). A humanized mouse model to study human immune response in xenotransplantation. Hepatobiliary & Pancreatic Diseases International, 11(5), 494-498. [More Information]
  • Yi, S., Ji, M., Wu, J., Ma, X., Phillips, P., Hawthorne, W., O'Connell, P. (2012). Adoptive Transfer With In Vitro Expanded Human Regulatory T Cells Protects Against Porcine Islet Xenograft Rejection via Interleukin-10 in Humanized Mice. Diabetes, 61(5), 1180-1191. [More Information]
  • Sun, L., Wu, J., Yi, S. (2012). Foxp3 is critical for human natural CD4+CD25+ regulatory T cells to suppress alloimmune response. Transplant Immunology, 26(2-3), 71-80. [More Information]
  • O'Connell, P., Yi, S., Carrington, E., Lew, A. (2010). Role of regulatory T cells in xenotransplantation. Current Opinion in Organ Transplantation, 15(2), 224-229. [More Information]
  • Hawthorne, W., Xing, X., Yi, S., Simond, D., Dong, Q., Ye, B., Tong, Q., Ye, Z., Wang, W. (2009). Investigation of porcine endogenous retrovirus in the conservation population of ningxiang pig. Transplantation Proceedings, 41(10), 4389-4393. [More Information]
  • Wu, J., Yi, S., Ouyang, L., Jimenez, E., Simond, D., Wang, W., Wang, Y., Hawthorne, W., O'Connell, P. (2008). In Vitro Expanded Human CD4+CD25+ Regulatory T Cells are Potent Suppressors of T-Cell-Mediated Xenogeneic Responses. Transplantation, 85(12), 1841-1848. [More Information]
  • Chandra, A., Ouyang, L., Wong, J., Ha, H., Walters, S., Patel, A., Hawthorne, W., Yi, S. (2007). Association between islet xenograft rejection mediated by activated macrophages and upregulated chemokines. Zhongnan Daxue Xuebao (Yixue Ban), 32(1), 26-35. [More Information]
  • Chandra, A., Ouyang, L., Yi, S., Wong, J., Ha, H., Walters, S., Patel, A., Stokes, R., Jardine, M., Hawthorne, W., O'Connell, P. (2007). Chemokine and toll-like receptor signaling in macrophage mediated islet xenograft rejection. Xenotransplantation, 14(1), 48-59. [More Information]
  • Yi, S., Wang, Y., Chandra, A., O'Hara, J., Wu, J., Ouyang, L., Burgess, J., Hawthorne, W., Wu, H., Chadban, S., O'Connell, P. (2007). Requirement of MyD88 for macrophage-mediated islet xenograft rejection after adoptive transfer. Transplantation, 83(5), 615-623. [More Information]
  • Yi, S., Ouyang, L., Ha, H., O'Hara, J., Chandra, A., Akima, S., Hawthorne, W., Patel, A., Stokes, R., O'Connell, P. (2005). Involvement of CCR5 Signaling in Macrophage Recruitment to Porcine Islet Xenografts. Transplantation, 80(10), 1468-1475. [More Information]
  • Yi, S., Hawthorne, W., Lehnert, A., Ha, H., Wong, J., Rooijen, N., Davey, K., Patel, A., Walters, S., Chandra, A., O'Connell, P. (2003). T Cell-Activated Macrophages Are Capable of Both Recognition and Rejection of Pancreatic Islet Xenografts. Journal of Immunology, 170(5), 2750-2758.

2014

  • Zhao, R., Tang, D., Yi, S., Li, W., Wu, C., Lu, Y., Hou, X., Song, J., Lin, P., Chen, L., et al (2014). Elevated peripheral frequencies of Th22 cells: a novel potent participant in obesity and type 2 diabetes. PLoS One, 9(1), 1-9. [More Information]
  • Jin, X., Wang, Y., Hawthorne, W., Hu, M., Yi, S., O'Connell, P. (2014). Enhanced Suppression of the Xenogeneic T-Cell Response in Vitro by Xenoantigen Stimulated and Expanded Regulatory T Cells. Transplantation, 97(1), 30-38. [More Information]

2013

  • Hu, M., Wu, J., Zhang, G., Wang, Y., Watson, D., Yi, S., Hawthorne, W., O'Connell, P., Alexander, S. (2013). Selective Depletion of Alloreactive T cells Leads to Long-Term Islet Allograft Survival Across a Major Histocompatibility Complex Mismatch in Diabetic Mice. Cell Transplantation, 22(10), 1929-1941. [More Information]
  • O'Connell, P., Cowan, P., Hawthorne, W., Yi, S., Lew, A. (2013). Transplantation of Xenogeneic Islets: Are We There Yet? Current Diabetes Reports, 13(5), 687-694. [More Information]

2012

  • Ji, M., Jin, X., Phillips, P., Yi, S. (2012). A humanized mouse model to study human immune response in xenotransplantation. Hepatobiliary & Pancreatic Diseases International, 11(5), 494-498. [More Information]
  • Yi, S., Ji, M., Wu, J., Ma, X., Phillips, P., Hawthorne, W., O'Connell, P. (2012). Adoptive Transfer With In Vitro Expanded Human Regulatory T Cells Protects Against Porcine Islet Xenograft Rejection via Interleukin-10 in Humanized Mice. Diabetes, 61(5), 1180-1191. [More Information]
  • Sun, L., Wu, J., Yi, S. (2012). Foxp3 is critical for human natural CD4+CD25+ regulatory T cells to suppress alloimmune response. Transplant Immunology, 26(2-3), 71-80. [More Information]

2010

  • O'Connell, P., Yi, S., Carrington, E., Lew, A. (2010). Role of regulatory T cells in xenotransplantation. Current Opinion in Organ Transplantation, 15(2), 224-229. [More Information]

2009

  • Hawthorne, W., Xing, X., Yi, S., Simond, D., Dong, Q., Ye, B., Tong, Q., Ye, Z., Wang, W. (2009). Investigation of porcine endogenous retrovirus in the conservation population of ningxiang pig. Transplantation Proceedings, 41(10), 4389-4393. [More Information]

2008

  • Wu, J., Yi, S., Ouyang, L., Jimenez, E., Simond, D., Wang, W., Wang, Y., Hawthorne, W., O'Connell, P. (2008). In Vitro Expanded Human CD4+CD25+ Regulatory T Cells are Potent Suppressors of T-Cell-Mediated Xenogeneic Responses. Transplantation, 85(12), 1841-1848. [More Information]

2007

  • Chandra, A., Ouyang, L., Wong, J., Ha, H., Walters, S., Patel, A., Hawthorne, W., Yi, S. (2007). Association between islet xenograft rejection mediated by activated macrophages and upregulated chemokines. Zhongnan Daxue Xuebao (Yixue Ban), 32(1), 26-35. [More Information]
  • Chandra, A., Ouyang, L., Yi, S., Wong, J., Ha, H., Walters, S., Patel, A., Stokes, R., Jardine, M., Hawthorne, W., O'Connell, P. (2007). Chemokine and toll-like receptor signaling in macrophage mediated islet xenograft rejection. Xenotransplantation, 14(1), 48-59. [More Information]
  • Yi, S., Wang, Y., Chandra, A., O'Hara, J., Wu, J., Ouyang, L., Burgess, J., Hawthorne, W., Wu, H., Chadban, S., O'Connell, P. (2007). Requirement of MyD88 for macrophage-mediated islet xenograft rejection after adoptive transfer. Transplantation, 83(5), 615-623. [More Information]

2005

  • Yi, S., Ouyang, L., Ha, H., O'Hara, J., Chandra, A., Akima, S., Hawthorne, W., Patel, A., Stokes, R., O'Connell, P. (2005). Involvement of CCR5 Signaling in Macrophage Recruitment to Porcine Islet Xenografts. Transplantation, 80(10), 1468-1475. [More Information]

2003

  • Yi, S., Hawthorne, W., Lehnert, A., Ha, H., Wong, J., Rooijen, N., Davey, K., Patel, A., Walters, S., Chandra, A., O'Connell, P. (2003). T Cell-Activated Macrophages Are Capable of Both Recognition and Rejection of Pancreatic Islet Xenografts. Journal of Immunology, 170(5), 2750-2758.

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