Professor Tania Sorrell

Professor of Clinical Infectious Diseases, Director Sydney Institute for Emerging Infectious Diseases and Biosecurity
Medicine (Immunology & Infectious Diseases), Westmead Clinical School
Westmead Millennium Institute for Medical Research

Telephone +61 2 9845 6012
Fax +61 2 9891 5317

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Biographical details

Tania Sorrell is the Director of the Sydney Institute for Emerging infectious Diseases and Biosecurity and Professor of Clinical Infectious Diseases at the University of Sydney, and a Senior Physician in Infectious Diseases at Westmead Hospital, Sydney. She has longstanding interests in prevention, diagnosis and treatment of Infectious Diseases, especially in immunocompromised hosts, and in the emergence of resistant micro-organisms. Her research in the serious fungal infection, cryptococcosis, has provided new insights into host-microbial interactions and new drug development. She has developed new diagnostics for fungal diseases and is on international committees developing guidelines for therapy. She has served/serves on state and national advisory committees in Infectious Diseases, pandemic planning for influenza, approval of therapeutic agents and both the Research and Human Ethics Committees of the National Health and Medical Research Council of Australia.

Research interests

Pathogenesis of invasive fungal infection, new diagnostics and therapeutics

PhD and master's project opportunities

Selected grants

2014

  • Signalling pathways and fungal virulence - the inositol polyphosphate biosynthetic pathway in Cryptococcus neoformans; Djordjevic J, Saiardi A, Sorrell T, Lev S; National Health and Medical Research Council (NHMRC)/Project Grants.

2013

  • Cryptococcal meningoencephalitis - fungal determinants of invasion of the CNS; Sorrell T, Djordjevic J, Combes V; National Health and Medical Research Council (NHMRC)/Project Grants.

2012

  • Modelling The Cost-Effectiveness Of Therapeutic Strategies For Invasive Candidiasis Among The Icu Population; Sorrell T, Graves N; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Developing functional research partnerships and student exchange, focused on relevant infectious diseases with the Eijkman Institute and Hasanuddin University, Indonesia; Yusuf I, Muljono D, Sorrell T, George J, Marais B, Douglas M; DVC International/IPDF Grant.
  • Sydney Infectious Diseases and Biosecurity Network (SIBRN); Sorrell T, Bennett B, Booy R, Crawford J, Dwyer D, Gilbert G, Giles F, Holmes A, Hossain L, Iredell J, Jones C, Kesson A, Kerridge I, Marais B, Simpson S, Sintchenko V, Ward M, Werder O, Britton W, Dhand N, Hunter C, Kamradt-Scott A, Mor S, Salkeld G, Shaw T, Smith F, Wood N; DVC Research/Research Network Scheme (SyReNS).
  • Discovering the genetic basis of fungal virulence; Meyer W, Huttley G, Sorrell T, Nevalainen H, Kwon-Chung K; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Investigating Novel Phospholipase C-mediated virulence and Drug Tolerance Mechanisms in Fungi; Djordjevic J, Lev S, Sorrell T; DVC Research/Bridging Support Grant.
  • Cell therapy for the prevention and treatment of invasive filamentous fungal infections in patients with haematological malignancies; Gottlieb D, Sorrell T; National Health and Medical Research Council (NHMRC)/Project Grants.

2010

  • Centre for Research Excellence in Critical and Emerging Infectious Diseases; Iredell J, Jones C, Sorrell T, Gilbert G, Kerridge I, Booy R, Dwyer D, Sintchenko V, Bennett B; National Health and Medical Research Council (NHMRC)/Centre of Clinical Research Excellence.
  • The fungal SEC14 secretory pathway and virulence; Djordjevic J, Williamson P, Sorrell T; National Health and Medical Research Council (NHMRC)/Project Grants.
  • The BD Influx High Speed Cell Sorter; Kefford R, Cunningham A, Bendall L, Clarke C, Harris D, Alexander S, Tam P, Sorrell T, Iredell J, Bryan T, Rizos H, Wang Y, Hebbard L; National Health and Medical Research Council (NHMRC)/Equipment Grants.
  • A Biosecurity and Biosafety Workshop with the University of Indonesia; Sorrell T; DVC International/IPDF Grant.

2009

  • Randomised trial of diagnostic strategies for invasive aspergillosis in at-risk haematology patients: funding extension; Chen S, Sorrell T; Cancer Council New South Wales/Research Project Grants.
  • Targeting Fungal Phospholipid Metabolism for Antifungal Drug Discovery; Jolliffe K, Ellis D, Sorrell T, Djordjevic J, Ellis D; National Health and Medical Research Council (NHMRC)/Project Grants.
  • The fungal phospholipase B pathway and virulence; Djordjevic J, Sorrell T; DVC Research/Bridging Support Grant.

2008

  • Predicting the risk of invasive candidiasis in critically ill patients; Sorrell T, Jones M, Paterson D, Lipman J, Playford E, Jones M, Iredell J; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Integrated Vibrational Spectroscopic Mapping for Archeological, Biological, Geological, Materials and Medical Research; Lay P, McNaughton D, Maschmeyer T, Potts D, Swain M, Grau G, Sorrell T, Ramzan I, Beardall J, Bernard C, Marshall C, Dutkiewicz A, Penny D, Wood B, Yang W, Soon L, Traini D, Carter E; Australian Research Council (ARC)/Linkage Infrastructure, Equipment and Facilities (LIEF).
  • Integrated Vibrational Spectroscopic Mapping for Archeological, Biological, Geological Materials, and Medical Research; Bernard C, Marshall C, Wood B, Potts D, Penny D, Dutkiewicz A, Grau G, Sorrell T, Swain M, Yang W, Soon L, Lay P, McNaughton D, Maschmeyer T, Ramzan I, Beardall J, Traini D, Carter E; Australian Research Council (ARC)/Linkage Infrastructure, Equipment and Facilities (LIEF).

2007

  • Odyssey Infrared imaging system; Grau G, Sorrell T; National Health and Medical Research Council (NHMRC)/Equipment Grants.
  • Twister microplate handle: A robotic system for the Bruker HTS-XT infrared module.; Lay P, Hunt N, Grau G, Sorrell T, Witting P; National Health and Medical Research Council (NHMRC)/Equipment Grants.

2006

  • Fungal Phospholipases: A Novel Drug Discovery Platform; Jolliffe K, Ellis D, Sorrell T, Ellis D; National Health and Medical Research Council (NHMRC)/Project Grants.

2005

  • Interdisciplinary Clinical And Health Ethic Research And Training To Improve Outcomes In Immunosuppressed Haematology Patients; Sorrell T, Bradstock K, Kerridge I, Gilbert G, Gottlieb D, MacIntyre C, Dwyer D, Ankeny R; National Health and Medical Research Council (NHMRC)/Centre of Clinical Research Excellence.
  • Vibrational Spectroscopy Microprobe/FESEM/AFM Imaging of Cells, Tissues and Materials; Lay P, Ringer S, Maschmeyer T, Sorrell T, McKenzie D, Eggleton B, Fleming S, et a; Australian Research Council (ARC)/Linkage Infrastructure, Equipment and Facilities (LIEF).
  • Regulation of secretion of the fungal virulence determinant, phospholipase B; Sorrell T, Djordjevic J, Wright L; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Adoptive Immunotherpay For Cmv, Vzv And Aspergillus Infection In The Immunocompromised; Gottlieb D, Sorrell T, Abendroth A; Anthony Rothe Foundation/Research in NSW.

2002

  • Cryptococcal phospholipases: structure, and potential targets for therapeutics; Wright L, Widmer A, Sorrell T; National Health and Medical Research Council (NHMRC)/Project Grants.

2001

  • The monocyte-macrophage P2X7 receptor and susceptibility to tuberculosis; Wiley J, Sorrell T; Community Health and Tuberculosis Australia (CHATA)/Research Grant.
  • Magnetic resonance methods of automated, non-invasive diagnosis of focal brain infections; Sorrell T, Mountford C, Tress B, Jones N, Himmelreich U; National Health and Medical Research Council (NHMRC)/Project Grants.

2000

  • Robust non-invasive diagnosis of focal infections in brain by magnetic resonance methods; Sorrell T, Towner R, Harper C, Mountford C; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Genetic and biochemical characterisation of cryptococcal phospholipases; Meyer W, Lee K, Wright L, Sorrell T; National Health and Medical Research Council (NHMRC)/Project Grants.

Selected publications

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Book Chapters

  • Lau, A., Stanley, K., Sorrell, T. (2013). Multiplex-Tandem PCR for Fungal Diagnostics. In Louise O'Connor and Barry Glynn (Eds.), Methods in Molecular Biology, Fungal Diagnostics: Methods and Protocols, (pp. 195-201). New York: Springer Science + Business Media.
  • Fox, D., Djordjevic, J., Sorrell, T. (2011). Signaling Cascades and Enzymes as Cryptococcus Virulence Factors. In J. Heitman, T Kozel, K. Kwon-Chung, J. Perfect & A. Casadevall (Eds.), Cryptococcus: From Human Pathogen to Model Yeast, (pp. 217-234). Washington, United States of America: ASM Press.
  • Sorrell, T. (2007). Detection of Fungal Metabolites. In Johan A Maertens and Kieren A. Marr (Eds.), Diagnosis of Fungal Infections, (pp. 121-132). New York: Informa Healthcare.
  • Carter, E., Marshall, C., Ali, M., Ganendren, R., Sorrell, T., Wright, L., Lee, Y., Chen, C., Lay, P. (2007). Infrared Spectroscopy of Microorganisms: Characterization, Identification, and Differentiation. In Katrin Kneipp, Ricardo Aroca, Harald Kneipp and Edeline Wentrup-Byrne (Eds.), New Approaches in Biomedical Spectroscopy, (pp. 64-84). Washington DC, United States: American Chemical Society.
  • Jones, P., Sorrell, T. (2005). Infections in the immunocompromised host. In Allen Yung, M McDonald, D Spelman, A Street, P Johnson, T Sorrell, J McCormack (Eds.), Infectious Diseases: A clinical approach, (pp. 412-420). Melbourne: IP Communications.
  • Sorrell, T., Mitchell, D., Iredell, J. (2005). Nocardia Species. In Gerald L. Mandell, MD, MACP, John E. Bennett, MD and Raphael Dolin, MD (Eds.), Principles and Practice of Infectious Diseases, (pp. 2916-2924). UK: Churchill Livingstone.
  • Yung, A., Stanley, P., Sorrell, T. (2005). Pyrexia of unknown origin. In Allen Yung, M McDonald, D Spelman, A Street, P Johnson, T Sorrell, J McCormack (Eds.), Infectious Diseases: A clinical approach, (pp. 75-88). Melbourne: IP Communications.
  • Iredell, J., Spelman, D., Sorrell, T. (2005). Septicaemia. In Allen Yung, M McDonald, D Spelman, A Street, P Johnson, T Sorrell, J McCormack (Eds.), Infectious Diseases: A clinical approach, (pp. 183-193). Melbourne: IP Communications.

Journals

  • Saijo, T., Chen, J., Chen, S., Rosen, L., Yi, J., Sorrell, T., Bennett, J., Holland, S., Browne, S., Kwong-Chung, K. (2014). Anti-GM-CSF autoantibodies are a risk factor for central nervous system infection by cryptococcus gattii in otherwise immunocompetent patients. mBio, Accepted for publication 11/2/14.
  • Biswas, C., Zuo, X., Chen, S., Schibeci, S., Forwood, J., Jolliffe, K., Sorrell, T., Djordjevic, J. (2014). Functional disruption of yeast metacaspase, Mca1, leads to miltefosine resistance and inability to mediate miltefosine-induced apoptotic effects. Fungal Genetics and Biology, 67, 71-81. [More Information]
  • Chen, S., Korman, T., Slavin, M., Marriott, D., Byth Wilson, K., Bak, N., Currie, B., Hajkowicz, K., Heath, C., Kidd, S., Meyer, W., Sorrell, T., et al (2013). Antifungal therapy and management of complications of cryptococcosis due to Cryptococcus gattii. Clinical Infectious Diseases, 57(4), 543-551. [More Information]
  • McMullan, B., Sorrell, T., Chen, S. (2013). Cryptococcus gattii infections: contemporary aspects of epidemiology, clinical manifestations and management of infection. Future Microbiology, 8(12), 1613-1631. [More Information]
  • Hueston, L., Toi, C., Jeoffreys, N., Sorrell, T., Gilbert, G. (2013). Diagnosis of Barmah Forest Virus Infection by a Nested Real-Time SYBR Green RT-PCR Assay. PLoS One, 8(7), 1-5. [More Information]
  • Biswas, C., Djordjevic, J., Zuo, X., Boles, E., Jolliffe, K., Sorrell, T., Chen, S. (2013). Functional characterization of the hexose transporter Hxt13p: An efflux pump that mediates resistance to miltefosine in yeast. Fungal Genetics and Biology, 61, 23-32. [More Information]
  • Morrissey, C., Chen, S., Sorrell, T., Milliken, S., Bardy, P., Bradstock, K., Szer, J., Halliday, C., Gilroy, N., Moore, J., et al (2013). Galactomannan and PCR versus culture and histology for directing use of antifungal treatment for invasive aspergillosis in high-risk haematology patients: a randomised controlled trial. Lancet Infectious Diseases, 13(6), 519-528. [More Information]
  • Ferguson, P., Gilroy, N., Faux, C., Mackay, I., Sloots, T., Nissen, M., Dwyer, D., Sorrell, T. (2013). Human rhinovirus C in adult haematopoietic stem cell transplant recipients with respiratory illness. Journal Of Clinical Virology, 56(3), 255-259. [More Information]
  • Biswas, C., Sorrell, T., Djordjevic, J., Zuo, X., Jolliffe, K., Chen, S. (2013). In vitro activity of miltefosine as a single agent and in combination with voriconazole or posaconazole against uncommon filamentous fungal pathogens. Journal of Antimicrobial Chemotherapy, 68(12), 2842-2846. [More Information]
  • Wiederhold, N., Najvar, L., Bocanegra, R., Kirkpatrick, W., Sorrell, T., Patterson, T. (2013). Limited Activity of Miltefosine in Murine Models of Cryptococcal Meningoencephalitis and Disseminated Cryptococcosis. Antimicrobial Agents and Chemotherapy, 57(2), 745-750. [More Information]
  • Lev, S., Desmarini, D., Li, C., Chayakulkeeree, M., Traven, A., Sorrell, T., Djordjevic, J. (2013). Phospholipase C of Cryptococcus neoformans Regulates Homeostasis and Virulence by Providing Inositol Trisphosphate as a Substrate for Arg1 Kinase. Infection and Immunity, 81(4), 1245-1255. [More Information]
  • Xiao, M., Guo, L., Kong, F., Wang, H., Sorrell, T., Li, R., Jiang, W., Chen, S., Xu, Y. (2013). Practical identification of eight medically important Trichosporon species by reverse line blot hybridization (RLB) assay and rolling circle amplification (RCA). Medical Mycology, 51(3), 300-308. [More Information]
  • Chen, S., Slavin, M., Heath, C., Playford, E., Byth Wilson, K., Marriott, D., Kidd, S., Bak, N., Currie, B., Hajkowicz, K., Meyer, W., Sorrell, T., et al (2012). Clinical Manifestations of Cryptococcus gattii Infection: Determinants of Neurological Sequelae and Death. Clinical Infectious Diseases, 55(6), 789-798. [More Information]
  • McMullan, B., Halliday, C., Sorrell, T., Judd, D., Sleiman, S., Marriott, D., Olma, T., Chen, S. (2012). Clinical Utility of the Cryptococcal Antigen Lateral Flow Assay in a Diagnostic Mycology Laboratory. PLoS One, 7(11), 1-6. [More Information]
  • Aminnejad, M., Diaz, M., Arabatzis, M., Castaneda, E., Lazera, M., Velegraki, A., Marriott, D., Sorrell, T., Meyer, W. (2012). Identification of Novel Hybrids Between Cryptococcus neoformans var.grubii VNI and Cryptococcus gattii VGII. Mycopathologia, 173(5-6), 337-346. [More Information]
  • Lev, S., Desmarini, D., Chayakulkeeree, M., Sorrell, T., Djordjevic, J. (2012). The Crz1/Sp1 Transcription Factor of Cryptococcus neoformans Is Activated by Calcineurin and Regulates Cell Wall Integrity. PLoS One, 7(12), 1-13. [More Information]
  • Wang, H., Xiao, M., Kong, F., Chen, S., Dou, H., Sorrell, T., Li, R., Xu, Y. (2011). Accurate and Practical Identification of 20 Fusarium Species by Seven-Locus Sequence Analysis and Reverse Line Blot Hybridization, and an In Vitro Antifungal Susceptibility Study. Journal of Clinical Microbiology, 49(5), 1890-1898. [More Information]
  • Ngamskulrungroj, P., Price, J., Sorrell, T., Perfect, J., Meyer, W. (2011). Cryptococcus Gattii Virulence Composite: Candidate Genes Revealed by Microarray Analysis of High and Less Virulent Vancouver Island Outbreak Strains. PLoS One, 6(1), e16076 - 1-e16076 - 12. [More Information]
  • Morrissey, C., Chen, S., Sorrell, T., Bradstock, K., Szer, J., Halliday, C., Gilroy, N., Schwarer, A., Slavin, M. (2011). Design issues in a randomized controlled trial of a pre-emptive versus empiric antifungal strategy for invasive aspergillosis in patients with high-risk hematologic malignancies. Leukemia and Lymphoma, 52(2), 179-193. [More Information]
  • Konstantinos, A., Simpson, G., Sorrell, T., Marais, B. (2011). Doing the right thing for tuberculosis control in the Torres Strait Islands. Medical Journal of Australia, 195(9), 512-512. [More Information]
  • Chen, S., Slavin, M., Sorrell, T. (2011). Echinocandin Antifungal Drugs in Fungal Infections A Comparison. Drugs, 71(1), 11-41. [More Information]
  • Ferguson, P., Gilroy, N., Sloots, T., Nissen, M., Dwyer, D., Sorrell, T. (2011). Evaluation of a clinical scoring system and directed laboratory testing for respiratory virus infection in hematopoietic stem cell transplant recipients. Transplant Infectious Disease (Print), 13(5), 448-455. [More Information]
  • Wang, T., Kong, F., Chen, S., Xiao, M., Sorrell, T., Wang, X., Wang, S., Sintchenko, V. (2011). Improved identification of Gordonia, Rhodococcus and Tsukamurella species by 5'-end 16S rRNA gene sequencing. Pathology, 43(1), 58-63. [More Information]
  • Zuo, X., Djordjevic, J., Oei Bijosono, J., Desmarini, D., Schibeci, S., Jolliffe, K., Sorrell, T. (2011). Miltefosine Induces Apoptosis-Like Cell Death in Yeast via Cox9p in Cytochrome c Oxidase. Molecular Pharmacology, 80(3), 476-485. [More Information]
  • Outhred, A., Watts, M., Chen, S., Sorrell, T. (2011). Nocardia infections of the face and neck. Current Infectious Disease Reports, 13(2), 132-140. [More Information]
  • Chen, S., Blyth, C., Sorrell, T., Slavin, M. (2011). Pneumonia and Lung Infections due to Emerging and Unusual Fungal Pathogens. Seminars in Respiratory and Critical Care Medicine, 32(6), 703-716. [More Information]
  • Chayakulkeeree, M., Johnston, S., Oei Bijosono, J., Lev, S., Williamson, P., Wilson, C., Zuo, X., Leal, A., Vainstein, M., Meyer, W., Sorrell, T., Djordjevic, J., et al (2011). SEC14 is a specific requirement for secretion of phospholipase B1 and pathogenicity of Cryptococcus neoformans. Molecular Microbiology, 80(4), 1088-1101. [More Information]
  • Blyth, C., Gomes, L., Sorrell, T., da Cruz, M., Sud, A., Chen, S. (2011). Skull-base osteomyelitis: Fungal vs. bacterial infection. Clinical Microbiology and Infection, 17(2), 306-311. [More Information]
  • Guo, L., Xiao, M., Kong, F., Chen, S., Wang, H., Sorrell, T., Jiang, W., Dou, H., Li, R., Xu, Y. (2011). Three-locus identification, genotyping, and antifungal susceptibilities of medically important Trichosporon species from China. Journal of Clinical Microbiology, 49(11), 3805-3811. [More Information]
  • Chen, S., Playford, E., Sorrell, T. (2010). Antifungal therapy in invasive fungal infections. Current Opinion in Pharmacology, 10(5), 522-30. [More Information]
  • Slavin, M., Sorrell, T., Marriott, D., Thursky, K., Nguyen, Q., Ellis, D., Morrissey, C., Chen, S. (2010). Candidaemia in adult cancer patients: risks for fluconazole-resistant isolates and death. Journal of Antimicrobial Chemotherapy, 65(5), 1042-1051. [More Information]
  • Blyth, C., Middleton, P., Harun, A., Sorrell, T., Meyer, W., Chen, S. (2010). Clinical associations and prevalence of Scedosporium spp. in Australian cystic fibrosis patients: identification of novel risk factors? Medical Mycology, 48(1), S37-S44. [More Information]
  • Perfect, J., Dismukes, W., Dromer, F., Goldman, D., Nguyen, M., Pappas, P., Powderly, W., Singh, N., Sobel, J., Sorrell, T., et al (2010). Clinical practice guidelines for the management of cryptococcal disease: 2010 update by the Infectious Diseases Society of America. Clinical Infectious Diseases, 50(3), 291-322. [More Information]
  • Lau, A., Halliday, C., Chen, S., Playford, E., Stanley, K., Sorrell, T. (2010). Comparison of Whole Blood, Serum and Plasma for Early Detection of Candidemia by Multiplex-Tandem PCR. Journal of Clinical Microbiology, 48(3), 811-816. [More Information]
  • Blyth, C., Harun, A., Middleton, P., Sleiman, S., Lee, O., Sorrell, T., Meyer, W., Chen, S. (2010). Detection of Occult Scedosporium Species in Respiratory Tract Specimens from Patients with Cystic Fibrosis by Use of Selective Media. Journal of Clinical Microbiology, 48(1), 314-316. [More Information]
  • Hale, K., Shaw, P., Dalla-Pozza, L., MacIntyre, C., Isaacs, D., Sorrell, T. (2010). Epidemiology of paediatric invasive fungal infections and a case-control study of risk factors in acute leukaemia or post stem cell transplant. British Journal of Haematology, 149(2), 263-272. [More Information]
  • Sorrell, T., Djordjevic, J., Jolliffe, K. (2010). Fungal phospholipid metabolism forantifungal drug discovery. Microbiology Australia, 31, 93-94.
  • Xiao, M., Kong, F., Sorrell, T., Cao, Y., Lee, O., Liu, Y., Sintchenko, V., Chen, S. (2010). Identification of Pathogenic Nocardia Species by Reverse Line Blot Hybridization Targeting the 16S rRNA and 16S-23S rRNA Gene Spacer Regions. Journal of Clinical Microbiology, 48(2), 503-511. [More Information]
  • Chen, S., Biswas, C., Bartley, R., Widmer, A., Pantarat, N., Obando Gutierrez, D., Djordjevic, J., Ellis, D., Jolliffe, K., Sorrell, T. (2010). In vitro antifungal activities of bis(alkylpyridinium)alkane compounds against pathogenic yeasts and molds. Antimicrobial Agents and Chemotherapy, 54(8), 3233-3240. [More Information]
  • Playford, E., Nimmo, G., Tilse, M., Sorrell, T. (2010). Increasing incidence of candidaemia: long-term epidemiological trends, Queensland, Australia, 1999-2008. Journal of hospital infection, 76(1), 46-51. [More Information]
  • Gilbert, N., Donlin, M., Gerik, K., Specht, C., Djordjevic, J., Wilson, C., Sorrell, T., Lodge, J. (2010). KRE genes are required for beta-1,6-glucan synthesis, maintenance of capsule architecture and cell wall protein anchoring in Cryptococcus neoformans. Molecular Microbiology, 76(2), 517-534. [More Information]
  • Playford, E., Lipman, J., Sorrell, T. (2010). Management of invasive candidiasis in the intensive care unit. Drugs, 70(7), 823-839. [More Information]
  • Krockenberger, M., Malik, R., Ngamskulrungroj, P., Trilles, L., Escandon, P., Dowd, S., Allen, C., Himmelreich, U., Canfield, P., Sorrell, T., Meyer, W. (2010). Pathogenesis of pulmonary Cryptococcus gattii Infection: A Rat model. Mycopathologia, 170(5), 315-330. [More Information]
  • Playford, E., Lipman, J., Sorrell, T. (2010). Prophylaxis, empirical and preemptive treatment of invasive candidiasis. Current Opinion in Critical Care, 16(5), 470-474. [More Information]
  • Sorrell, T., Chen, S. (2010). Recent advances in management of cryptococcal meningitis: commentary. F1000 Medicine Reports, 2, 82. [More Information]
  • Wang, X., Xiao, M., Kong, F., Sintchenko, V., Wang, H., Wang, B., Lian, S., Sorrell, T., Chen, S. (2010). Reverse line blot hybridization and DNA sequencing studies of the 16S-23S rRNA gene intergenic spacer regions of five emerging pathogenic Nocardia species. Journal of Medical Microbiology, 59(Pt 5), 548-555. [More Information]
  • Kong, F., Wang, H., Zhang, E., Sintchenko, V., Xiao, M., Sorrell, T., Chen, X., Chen, S. (2010). SecA1 Gene Sequence Polymorphisms for Species Identification of Nocardia and Recognition of Intraspecies Genetic Diversity. Journal of Clinical Microbiology, 48(11), 3928-3934. [More Information]
  • Blyth, C., Gomes, L., Sorrell, T., da Cruz, M., Sud, A., Chen, S. (2010). Skull-base osteomyelitis: fungal versus bacterial infection. Clinical Microbiology and Infection, DOI: 10.1111/j.1469-0691.2010.03231.x, 1-6. [More Information]
  • Bialasiewicz, S., Rockett, R., Whiley, D., Abed, Y., Allander, T., Binks, M., Boivin, G., Cheng, A., Chung, J., Gilroy, N., Sorrell, T., et al (2010). Whole Genome Characterisation and Genotyping of Global WU Polyomavirus Strains. Journal of Virology, 84(12), 6229-34. [More Information]
  • Playford, E., Lipman, J., Kabir, M., McBryde, E., Nimmo, G., Lau, A., Sorrell, T. (2009). Assessment of clinical risk predictive rules for invasive candidiasis in a prospective multicentre cohort of ICU patients. Intensive Care Medicine, 35(12), 2141-2145. [More Information]
  • Kong, F., Chen, S., Chen, X., Sintchenko, V., Halliday, C., Cai, L., Tong, Z., Lee, O., Sorrell, T. (2009). Assignment of Reference 5’-end 16S rDNA Sequences and Species-Specific Sequence Polymorphisms Improves Species Identification of Nocardia. The Open Microbiology Journal, 3, 97-105. [More Information]
  • Brown, G., Sorrell, T. (2009). Building quality in health--the need for clinical researchers. Medical Journal of Australia, 190(11), 627-629. [More Information]
  • Chen, S., Marriott, D., Playford, E., Nguyen, Q., Ellis, D., Meyer, W., Sorrell, T., Slavin, M. (2009). Candidaemia with uncommon Candida species: Predisposing factors, outcome, antifungal susceptibility, and implications for management. Clinical Microbiology and Infection, 15(7), 662-669. [More Information]
  • van Hal, S., Marriott, D., Chen, S., Nguyen, Q., Sorrell, T., Ellis, D., Slavin, M. (2009). Candidemia following solid organ transplantation in the era of antifungal prophylaxis: the Australian experience. Transplant Infectious Disease (Print), 11(2), 122-127. [More Information]
  • Gordon-Thomson, C., Kumari, A., Tomkins, L., Holford, P., Djordjevic, J., Wright, L., Sorrell, T., Moore, G. (2009). Chitotriosidase and gene therapy for fungal infections. Cellular and Molecular Life Sciences, 66(6), 1116-1125. [More Information]
  • Lau, A., Chen, S., Sleiman, S., Sorrell, T. (2009). Current status and future perspectives on molecular and serological methods in diagnostic mycology. Future Microbiology, 4(9), 1185-1222. [More Information]
  • Marriott, D., Playford, E., Chen, S., Slavin, M., Nguyen, Q., Ellis, D., Sorrell, T. (2009). Determinants of mortality in non-neutropenic ICU patients with candidaemia. Critical Care, 13(4), 1-8. [More Information]
  • Sorrell, T., Chen, S. (2009). Fungal-derived immune modulating molecules. Advances in Experimental Medicine and Biology, 666, 108-120.
  • Blyth, C., Chen, S., Slavin, M., Serena, C., Nguyen, Q., Marriott, D., Ellis, D., Meyer, W., Sorrell, T. (2009). Not just little adults: candidemia epidemiology, molecular characterization, and antifungal susceptibility in neonatal and pediatric patients. Pediatrics (English Edition), 123(5), 1360-1368. [More Information]
  • Heath, C., Slavin, M., Sorrell, T., Handke, R., Harun, A., Phillips, M., Nguyen, Q., Delhaes, L., Ellis, D., Meyer, W., Chen, S., et al (2009). Population-based surveillance for scedosporiosis in Australia: Epidemiology, disease manifestations and emergence of Scedosporium aurantiacum infection. Clinical Microbiology and Infection, 15(7), 689-693. [More Information]
  • Wang, H., Kong, F., Sorrell, T., Wang, B., McNicholas, P., Pantarat, N., Ellis, D., Xiao, M., Widmer, A., Chen, S. (2009). Rapid detection of ERG11 gene mutations in clinical Candida albicans isolates with reduced susceptibility to fluconazole by rolling circle amplification and DNA sequencing. BMC Microbiology, 9, 167-1-167-12. [More Information]
  • Himmelreich, U., Malik, R., Kuhn, T., Daniel, H., Somorjai, R., Dolenko, B., Sorrell, T. (2009). Rapid Etiological Classification of Meningitis by NMR Spectroscopy Based on Metabolite Profiles and Host Response. PLoS One, 4(4), e5328-1-e5328-8. [More Information]
  • Kesson, A., Bellemore, M., O'Mara, T., Ellis, D., Sorrell, T. (2009). Scedosporium prolificans osteomyelitis in an immunocompetent child treated with a novel agent, hexadecylphospocholine (miltefosine), in combination with terbinafine and voriconazole: a case report. Clinical Infectious Diseases, 48(9), 1257. [More Information]
  • Obando Gutierrez, D., Pantarat, N., Handke, R., Koda, Y., Widmer, A., Djordjevic, J., Ellis, D., Sorrell, T., Jolliffe, K. (2009). Synthesis, antifungal, haemolytic and cytotoxic activities of a series of bis(alkylpyridinium)alkanes. Bioorganic and Medicinal Chemistry, 17(17), 6329-6339. [More Information]
  • Ngamskulrungroj, P., Sorrell, T., Chindamporn, A., Poonwan, N., Chaiprasert, A., Meyer, W. (2008). Association between fertility and molecular sub-type of global isolates of Cryptococcus gattii molecular type VGII. Medical Mycology, 46(7), 655-673. [More Information]
  • Playford, E., Marriott, D., Nguyen, Q., Chen, S., Ellis, D., Slavin, M., Sorrell, T. (2008). Candidemia in nonneutropenic critically ill patients: Risk factors for non-albicans Candida spp. Critical Care Medicine, 36(7), 2034-2039. [More Information]
  • Chen, S., Tong, Z., Lee, O., Halliday, C., Playford, E., Widmer, A., Kong, F., Wu, C., Sorrell, T. (2008). Clinician response to Candida organisms in the urine of patients attending hospital. European Journal of Clinical Microbiology and Infectious Diseases, 27(3), 201-208. [More Information]
  • Lau, A., Sorrell, T., Lee, O., Stanley, K., Halliday, C. (2008). Colony Multiplex-Tandem PCR for Rapid, Accurate Identification of Fungal Cultures. Journal of Clinical Microbiology, 46(12), 4058-4060. [More Information]
  • Delhaes, L., Harun, A., Chen, S., Nguyen, Q., Slavin, M., Heath, C., Maszewska, K., Halliday, C., Robert, V., Sorrell, T., Meyer, W., et al (2008). Molecular typing of Australian Scedosporium isolates showing genetic variability and numerous S. aurantiacum. Emerging Infectious Diseases, 14(2), 282-290. [More Information]
  • Lau, A., Sorrell, T., Chen, S., Stanley, K., Iredell, J., Halliday, C. (2008). Multiplex-Tandem PCR: A Novel Platform for the Rapid Detection and Identification of Fungal Pathogens from Blood Culture Specimens. Journal of Clinical Microbiology, 46(9), 3021-3027. [More Information]
  • Sorrell, T., Himmelreich, U. (2008). NMR in mycology. Current Fungal Infection Reports, 2, 149-156.
  • Zhou, X., Kong, F., Sorrell, T., Wang, H., Duan, Y., Chen, S. (2008). Practical method for detection and identification of Candida, Aspergillus and Scedosporium using rolling circle amplification (RCA). Journal of Clinical Microbiology, 46(7), 2423-2427. [More Information]
  • Kong, F., Tong, Z., Chen, X., Sorrell, T., Wang, B., Wu, Q., Ellis, D., Chen, S. (2008). Rapid identification and differentiation of Trichophyton species, based on sequence polymorphisms of the ribosomal internal transcribed spacer regions, by rolling-circle amplification. Journal of Clinical Microbiology, 46(4), 1192-1199. [More Information]
  • Branley, J., Roy, B., Dwyer, D., Sorrell, T. (2008). Real-time PCR detection and quantitation of Chlamydophila psittaci in human and avian specimens from a veterinary clinic cluster. European Journal of Clinical Microbiology and Infectious Diseases, 27(4), 269-273. [More Information]
  • Thursky, K., Playford, E., Seymour, J., Sorrell, T., Ellis, D., Guy, S., Gilroy, N., Chu, J., Shaw, D. (2008). Recommendations for the treatment of established fungal infections. Internal Medicine Journal, 38(6B), 496-520. [More Information]
  • De Pauw, B., Walsh, T., Donnelly, J., Stevens, D., Edwards, J., Calandra, T., Pappas, P., Maertens, J., Lortholary, O., Sorrell, T., et al (2008). Revised definitions of Invasive fungal disease from the European Organisation for Research and treatmentof Cancer. Clinical Infectious Diseases, 46(12), 1813-1821. [More Information]
  • Chayakulkeeree, M., Sorrell, T., Siafakas, A., Wilson, C., Pantarat, N., Gerik, K., Boadle, R., Djordjevic, J. (2008). Role and mechanism of phosphatidylinositol-specific phospholipase C in survival and virulence of Cryptococcus neoformans. Molecular Microbiology, 69(4), 809-826. [More Information]
  • Chen, S., Sorrell, T. (2007). Antifungal agents. Medical Journal of Australia, 187(7), 404-409. [More Information]
  • Siafakas, A., Sorrell, T., Wright, L., Wilson, C., Larsen, M., Boadle, R., Williamson, P., Djordjevic, J. (2007). Cell wall-linked cryptococcal phospholipase B1 is a source of secreted enzyme and a determinant of cell wall integrity. Journal of Biological Chemistry, 282(52), 37508-37514. [More Information]
  • Wu, Q., Chen, S., Santangelo, R., Martin, P., Malik, R., Sorrell, T. (2007). Cryptococcal phospholipase B antigen is not detected in serum of patients infected with Cryptococcus neoformans using a sandwich enzyme-linked immunosorbent assay. FEMS Yeast Research, 7(3), 465-470. [More Information]
  • Plummer, R., Bodkin, J., Power, D., Pantarat, N., Bubb, W., Kuchel, P., Sorrell, T. (2007). Effect of caspofungin on metabolite profiles of Aspergillus species determined by nuclear magnetic resonance spectroscopy. Antimicrobial Agents and Chemotherapy, 51(11), 4077-4084. [More Information]
  • Tong, Z., Widmer, A., Sorrell, T., Guse, Z., Jolliffe, K., Halliday, C., Lee, O., Kong, F., Wright, L., Chen, S. (2007). In Vitro Activities of Miltefosine and Two Novel Antifungal Biscationic Salts against a Panel of 77 Dermatophytes. Antimicrobial Agents and Chemotherapy, 51(6), 2219-2222. [More Information]
  • Plummer, R., Bodkin, J., Yau, T., Power, D., Pantarat, N., Larkin, T., Szekely, D., Bubb, W., Sorrell, T., Kuchel, P. (2007). Modelling Staphylococcus aureus-induced septicemia using NMR. Magnetic Resonance in Medicine, 58(4), 656-665. [More Information]
  • Zeng, X., Kong, F., Halliday, C., Chen, S., Lau, A., Playford, E., Sorrell, T. (2007). Reverse line blot (RLB) hybridization assay for the identification of medically important fungi from culture and clinical specimens. Journal of Clinical Microbiology, , 1-40. [More Information]
  • Jones, P., Turner, K., Djordjevic, J., Sorrell, T., Wright, L., George, A. (2007). Role of Conserved Active Site Residues in Catalysis by Phospholipase B1 from Cryptococcus neoformans. Biochemistry, 46(35), 10024-10032. [More Information]
  • Obando Gutierrez, D., Widmer, A., Wright, L., Sorrell, T., Jolliffe, K. (2007). Synthesis, antifungal and antimicrobial activity of alkylphospholipids. Bioorganic and Medicinal Chemistry, 15(15), 5158-5165. [More Information]
  • Ng, C., Singhal, V., Widmer, A., Wright, L., Sorrell, T., Jolliffe, K. (2007). Synthesis, antifungal and haemolytic activity of a series of bis(pyridinium)alkanes. Bioorganic and Medicinal Chemistry, 15(10), 3422-3429. [More Information]
  • Chen, S., Slavin, M., Nguyen, Q., Marriott, D., Playford, E., Ellis, D., Sorrell, T. (2006). Active surveillance for candidemia, Australia. Emerging Infectious Diseases, 12(10). [More Information]
  • Playford, E., Webster, A., Sorrell, T., Craig, J. (2006). Antifungal agents for preventing fungal infections in non-neutropenic critically ill and surgical patients: systematic review and meta-analysis of randomized clinical trials. Journal of Antimicrobial Chemotherapy. [More Information]
  • Playford, E., Webster, A., Sorrell, T., Craig, J. (2006). Antifungal agents for preventing fungal infections in non-neutropenic critically ill patients. Cochrane Database of Systematic Reviews, 1(1), CD004920. [More Information]
  • Coen, M., Bodkin, J., Power, D., Bubb, W., Himmelreich, U., Kuchel, P., Sorrell, T. (2006). Antifungal effects on metabolite profiles of medically important yeast species measured by nuclear magnetic resonance spectroscopy. Antimicrobial Agents and Chemotherapy, 50(12), 4018-4026. [More Information]
  • Sorrell, T., Wright, L., Malik, R., Himmelreich, U. (2006). Application of proton nuclear magnetic resonance spectroscopy to the study of Cryptococcus and cryptococcosis. FEMS Yeast Research, 6(4), 558-566.
  • Anaissie, E., Segal, B., Graybill, J., Arndt, C., Perfect, J., Kleinberg, M., Pappas, P., Benjamin, D., Rubin, M., Sorrell, T., et al (2006). Clinical research in the lay press: irresponsible journalism raises a huge dose of doubt. Clinical Infectious Diseases, 43(8), 1031-1039.
  • Ng, C., Obando Gutierrez, D., Widmer, A., Wright, L., Sorrell, T., Jolliffe, K. (2006). Correlation of antifungal activity with fungal phospholipase inhibition using a series of bisquaternary ammonium salts. Journal of Medicinal Chemistry, 49(2), 811-816. [More Information]
  • Wright, L., Santangelo, R., Ganendren, R., Payne, J., Djordjevic, J., Sorrell, T. (2006). Cryptococcal lipid metabolism: phospholipase B1 is implicated in transcellular metabolism of macrophage-derived lipids. Eukaryotic Cell, 6(1), 37-47. [More Information]
  • Lau, A., Chen, S., Sorrell, T., Carter, D., Malik, R., Martin, P., Halliday, C. (2006). Development and clinical application of a panfungal PCR assay to detect and identify fungal DNA in tissue specimens. Journal of Clinical Microbiology, (doi:10.1128/JCM.01862-06) 45 (2)(45 (2)), 380-385. [More Information]
  • Widmer, A., Wright, L., Obando Gutierrez, D., Handke, R., Ganendren, R., Ellis, D., Sorrell, T. (2006). Hexadecylphosphocholine (miltefosine) has broad-spectrum fungicidal activity and is efficacious in a mouse model of cryptococcosis. Antimicrobial Agents and Chemotherapy, 50(2), 414-421. [More Information]
  • Siafakas, A., Wright, L., Sorrell, T., Djordjevic, J. (2006). Lipid rafts in Cryptococcus neoformans concentrate the virulence determinants phospholipase B1 and Cu/Zn superoxide dismutase. Eukaryotic Cell, 5(3), 488-498. [More Information]
  • Turner, K., Wright, L., Sorrell, T., Djordjevic, J. (2006). N-linked glycosylation sites affect secretion of cryptococcal phospholipase B1, irrespective of glycosylphosphatidylinositol anchoring. BBA - Bioenergetics, 1760 (10), 1569-1579. [More Information]
  • Ganendren, R., Carter, E., Sorrell, T., Widmer, A., Wright, L. (2006). Phospholipase B activity enhances adhesion of Cryptococcus neoformans to a human lung epithelial cell line. Microbes and Infection, 8(4), 1006-1015. [More Information]
  • Halliday, C., Hoile, R., Sorrell, T., James, G., Yadav, S., Shaw, P., Bleakley, M., Bradstock, K., Chen, S. (2006). Role of prospective screening of blood for invasive aspergillosis by polymerase chain reaction in febrile neutropenic recipients of haematopoietic stem cell transplants and patients with acute leukaemia. British Journal of Haematology, 132(4), 478-486. [More Information]
  • Playford, E., Kong, F., Sun, Y., Wang, H., Halliday, C., Sorrell, T. (2006). Simultaneous detection and identification of Candida, Aspergillus, and Cryptococcus species by reverse line blot hybridization. Journal of Clinical Microbiology, 44(3), 876-880. [More Information]
  • Playford, E., Webster, A., Sorrell, T., Craig, J. (2006). Systematic review and meta-analysis of antifungal agents for preventing fungal infections in liver transplant recipients. European Journal of Clinical Microbiology and Infectious Diseases, 25(9), 549-561. [More Information]
  • Sorrell, T., Lonsdale, C. (2006). Urgent strategic research into influenza to inform health policy and protect the public. Medical Journal of Australia, 185(10), S77-S79. [More Information]
  • Himmelreich, U., Somorjai, R., Dolenko, B., Daniel, H., Sorrell, T. (2005). A rapid screening test to distinguish between Candida albicans and Candida dubliniensis using NMR spectroscopy. FEMS Microbiology Letters, 251(2), 327-32. [More Information]
  • Santangelo, R., Chen, S., Sorrell, T., Wright, L. (2005). Detection of antibodies to phospholipase B in patients infected with Cryptococcus neoformans by enzyme-linked immunosorbent assay (ELISA). Medical Mycology, 43(4), 335-341. [More Information]
  • Halliday, C., Wu, Q., James, G., Sorrell, T. (2005). Development of a Nested Qualitative Real-Time PCR Assay To Detect Aspergillus Species DNA in Clinical Specimens. Journal of Clinical Microbiology, 43(10), 5366-5368. [More Information]
  • Dzendrowskyj, T., Dolenko, B., Sorrell, T., Somorjai, R., Malik, R., Mountford, C., Himmelreich, U. (2005). Diagnosis of cerebral cryptococcoma using a computerized analysis of 1H NMR spectra in an animal model. Diagnostic microbiology and infectious disease, 52(2), 101-5. [More Information]
  • Himmelreich, U., Accurso, R., Malik, R., Dolenko, B., Somorjai, R., Gupta, R., Gomes, L., Mountford, C., Sorrell, T. (2005). Identification of Staphylococcus aureus brain abscesses: rat and human studies with 1H MR spectroscopy. Radiology, 236(1), 261-70. [More Information]
  • Coen, M., O'Sullivan, M., Bubb, W., Kuchel, P., Sorrell, T. (2005). Proton nuclear magnetic resonance-based metabonomics for rapid diagnosis of meningitis and ventriculitis. Clinical Infectious Diseases, 41(11), 1582-1590. [More Information]
  • Djordjevic, J., Del Poeta, M., Sorrell, T., Turner, K., Wright, L. (2005). Secretion of cryptococcal phospholipase B1 (PLB1) is regulated by a glycosylphosphatidylinositol (GPI) anchor. Biochemical Journal, 389(Part 3), 803-812. [More Information]
  • Wright, L., Payne, J., Santangelo, R., Simpanya, M., Chen, S., Widmer, A., Sorrell, T. (2004). Cryptococcal Phospholipases: A Novel Lysophospholipase Discovered In The Pathogenic Fungus Cryptococcus Gattii. Biochemical Journal, 384(2), 377-384.
  • Slavin, M., Szer, J., Grigg, A., Roberts, A., Seymour, J., Sasadeusz, J., Thursky, K., Chen, S., Morrissey, C., Heath, C., Sorrell, T. (2004). Guidelines for the use of antifungal agents in the treatment of invasive Candida and mould infections. Internal Medicine Journal, 34, 192-200.
  • Ganendren, R., Widmer, A., Singhal, V., Wilson, C., Sorrell, T., Wright, L. (2004). In Vitro Antifungal Activity of Inhibitors of Phospholipases from the Fungal Pathogen Cryptococcus neoformans. Antimicrobial Agents and Chemotherapy, 48(5), 1561-1569.
  • Chang, Y., Wright, L., Tscharke, R., Sorrell, T., Wilson, C., Kwong-Chung, K. (2004). Regulatory Roles For The Homeodomain And C2H2 Zinc Finger Regions Of Cryptococcus Neoformans Ste12Alphap. Molecular Microbiology, 53(5), 1385-96.
  • Santangelo, R., Zoellner, H., Sorrell, T., Wilson, C., Bolitho (nee Donald), C., Djordjevic, J., Yi, S., Wright, L. (2004). Role Of Extracellular Phospholipases And Mononuclear Phagocytes In Dissemination Of Cryptococcosis In A Murine Model. Infection and Immunity, 72(4), 2229-2239.
  • Baumgartner, R., Somorjai, R., Bowman, C., Sorrell, T., Mountford, C., Himmelreich, U. (2004). Unsupervised Feature Dimension Reduction For Classification Of Mr Spectra. Magnetic resonance imaging, 22(2), 251-256.
  • Coe, J., Wilson, C., Sorrell, T., Latouche, G., Wright, L. (2003). Cloning of CnLYS01, a novel extracellular lysophospholipase of the pathogenic fungus cryptococcus neoformans. Gene, 316(1), 67-78.
  • Himmelreich, U., Allen, C., Dowd, S., Malik, R., Shehan, B., Mountford, C., Sorrell, T. (2003). Identification of metabolites of importance in the pathogenesis of pulmonary cryptoccoma using nuclear magnetic resonance spectroscopy. Microbes and Infection, 5(4), 285-290.
  • Kidd, S., Sorrell, T., Meyer, W. (2003). Isolation of two molecualr types of Cryptococcus neoformans var. gattii from insect frass. Medical Mycology, 41(2), 171-176.
  • Latouche, G., Huynh, M., Sorrell, T., Meyer, W. (2003). PCR-restriction fragment length polymorphism analysis of the phospholipase B (PLB1) gene for subtyping of cryptococcus neoformans isolates. Applied and Environmental Microbiology, 69(4), 2080-2086.
  • Himmelreich, U., Somorjai, R., Dolenko, B., Lee, O., Daniel, H., Murray, R., Mountford, C., Sorrell, T. (2003). Rapid identification of Candida Species by Using Nuclear Magnetic Resonance Spectroscopy and a Statistical classification strategy. Applied and Environmental Microbiology, 69(8), 4566-4574.
  • Murray, R., Himmelreich, U., Gomes, L., Ingham, N., Sorrell, T. (2002). Cerebral nocardiosis characterized by Magnetic Resonance Spectroscopy in vivo. Clinical Infectious Diseases, 34, 849-852.
  • Himmelreich, U., Bourne, R., Sorrell, T., Mountford, C., Somorjai, R. (2002). Identification of Cryptococcus neoformans by Magnetic Resonance Spectroscopy. Microbiology Australia, , 31-33.
  • Latouche, G., Sorrell, T., Meyer, W. (2002). Isolation and characterisation of the phospholipase B gene of Cryptococcus neoformans var. gattii. FEMS Yeast Research, 2(4), 551-561.
  • Wright, L., Bubb, W., Davidson, J., Santangelo, R., Krockenberger, M., Himmelreich, U., Sorrell, T. (2002). Metabolites released by Cryptococcus neoformans var. neoformans and var. gattii differentially affect human neutrophil function. Microbes and Infection, 4(14), 1427-1438.
  • Wright, L., Chen, S., Wilson, C., Simpanya, M., Blackstock, R., Cox, G., Murphy, J., Sorrell, T. (2002). Strain-dependent effects of environmental signals on the production of extracellular phospholipase by Cryptococcus neoformans. FEMS Microbiology Letters, 209(2), 175-181.
  • Himmelreich, U., Dzendrowskyj, T., Allen, C., Dowd, S., Malik, R., Shehan, B., Russell, P., Mountford, C., Sorrell, T. (2001). Cryptococcomas distinguished from gliomas with MR spectroscopy: an experimental rat and cell culture study. Radiology, 220, 122-128.
  • Sorrell, T. (2001). Cryptococcus neoformans variety gatti. Medical Mycology, 39, 155-168.
  • Chen, S., Wright, L., Sorrell, T., Cox,, G., McDade, H., Tucker, S., Gottfredsson, M., Leidich, S., Casadevall, A., Ghannoum, M., et al (2001). Extracellular phospholipase activity is a virulence factor for cryptococcus neoformans. Molecular Microbiology, 39, 166-175.
  • Bourne, R., Himmelreich, U., Mountford, C., Sorrell, T., Sharma, A. (2001). Identification of Enterococcus, Streptococcus and Staphylococcus by multivariate analysis of Proton Magnetic Resonance Spectroscopic data from plate cultures. Journal of Clinical Microbiology, 39(8), 2916-2923.
  • Daniel, H., Sorrell, T., Meyer, W. (2001). Partial sequence analysis of the actin gene and its potential for studying the phylogeny of Candida species and their teleomorphs. International Journal of Systematic and Evolutionary Microbiology, 51, 1593-1606.
  • Meyer, W., Sorrell, T., Maszewska, K. (2001). PCR fingerprinting: a convenient molecular tool to distinguish between candida duliniensis and Candida albicans. Medical Mycology, 39, 185-193.

Conferences

  • Krockenberger, M., Malik, R., Ngamskulrungroj, P., Dowd, S., Meyer, W., Sorrell, T. (2008). Pathogenesis of Cryptococcosis caused by Cryptococcus gattii in a Rat Model of Disease. 7th International Conference on Cryptococcus and Cryptococcosis 2008.
  • Marriott, D., Playford, D., Nguyen, Q., Chen, S., Ellis, D., Slavin, M., Sorrell, T. (2006). Candidaemia in the Australian intensive care unit: Epidemiology, clinical features and outcome from a 3 year nationwide study. Australian Candidaemia Study, Australia: Elsevier.
  • Playford, E., Webster, A., Craig, J., Sorrell, T. (2003). Antifungal prophylaxis in critically-ill ICU and surgical patients: A meta-analysis. 43rd ICAAC, American Society for Microbiology.
  • Playford, E., Webster, A., Craig, J., Sorrell, T. (2003). Antifungal prophylaxis in solid organ transplant recipients: A meta-analysis. 43rd ICAAC, American Society for Microbiology.

Patents

  • Widmer, A., Sorrell, T., Wright, L., Jolliffe, K. (2011). Patent Family: Bis-cationic compounds and use thereof. Patent No. 2004289375, 7947854.

2014

  • Saijo, T., Chen, J., Chen, S., Rosen, L., Yi, J., Sorrell, T., Bennett, J., Holland, S., Browne, S., Kwong-Chung, K. (2014). Anti-GM-CSF autoantibodies are a risk factor for central nervous system infection by cryptococcus gattii in otherwise immunocompetent patients. mBio, Accepted for publication 11/2/14.
  • Biswas, C., Zuo, X., Chen, S., Schibeci, S., Forwood, J., Jolliffe, K., Sorrell, T., Djordjevic, J. (2014). Functional disruption of yeast metacaspase, Mca1, leads to miltefosine resistance and inability to mediate miltefosine-induced apoptotic effects. Fungal Genetics and Biology, 67, 71-81. [More Information]

2013

  • Chen, S., Korman, T., Slavin, M., Marriott, D., Byth Wilson, K., Bak, N., Currie, B., Hajkowicz, K., Heath, C., Kidd, S., Meyer, W., Sorrell, T., et al (2013). Antifungal therapy and management of complications of cryptococcosis due to Cryptococcus gattii. Clinical Infectious Diseases, 57(4), 543-551. [More Information]
  • McMullan, B., Sorrell, T., Chen, S. (2013). Cryptococcus gattii infections: contemporary aspects of epidemiology, clinical manifestations and management of infection. Future Microbiology, 8(12), 1613-1631. [More Information]
  • Hueston, L., Toi, C., Jeoffreys, N., Sorrell, T., Gilbert, G. (2013). Diagnosis of Barmah Forest Virus Infection by a Nested Real-Time SYBR Green RT-PCR Assay. PLoS One, 8(7), 1-5. [More Information]
  • Biswas, C., Djordjevic, J., Zuo, X., Boles, E., Jolliffe, K., Sorrell, T., Chen, S. (2013). Functional characterization of the hexose transporter Hxt13p: An efflux pump that mediates resistance to miltefosine in yeast. Fungal Genetics and Biology, 61, 23-32. [More Information]
  • Morrissey, C., Chen, S., Sorrell, T., Milliken, S., Bardy, P., Bradstock, K., Szer, J., Halliday, C., Gilroy, N., Moore, J., et al (2013). Galactomannan and PCR versus culture and histology for directing use of antifungal treatment for invasive aspergillosis in high-risk haematology patients: a randomised controlled trial. Lancet Infectious Diseases, 13(6), 519-528. [More Information]
  • Ferguson, P., Gilroy, N., Faux, C., Mackay, I., Sloots, T., Nissen, M., Dwyer, D., Sorrell, T. (2013). Human rhinovirus C in adult haematopoietic stem cell transplant recipients with respiratory illness. Journal Of Clinical Virology, 56(3), 255-259. [More Information]
  • Biswas, C., Sorrell, T., Djordjevic, J., Zuo, X., Jolliffe, K., Chen, S. (2013). In vitro activity of miltefosine as a single agent and in combination with voriconazole or posaconazole against uncommon filamentous fungal pathogens. Journal of Antimicrobial Chemotherapy, 68(12), 2842-2846. [More Information]
  • Wiederhold, N., Najvar, L., Bocanegra, R., Kirkpatrick, W., Sorrell, T., Patterson, T. (2013). Limited Activity of Miltefosine in Murine Models of Cryptococcal Meningoencephalitis and Disseminated Cryptococcosis. Antimicrobial Agents and Chemotherapy, 57(2), 745-750. [More Information]
  • Lau, A., Stanley, K., Sorrell, T. (2013). Multiplex-Tandem PCR for Fungal Diagnostics. In Louise O'Connor and Barry Glynn (Eds.), Methods in Molecular Biology, Fungal Diagnostics: Methods and Protocols, (pp. 195-201). New York: Springer Science + Business Media.
  • Lev, S., Desmarini, D., Li, C., Chayakulkeeree, M., Traven, A., Sorrell, T., Djordjevic, J. (2013). Phospholipase C of Cryptococcus neoformans Regulates Homeostasis and Virulence by Providing Inositol Trisphosphate as a Substrate for Arg1 Kinase. Infection and Immunity, 81(4), 1245-1255. [More Information]
  • Xiao, M., Guo, L., Kong, F., Wang, H., Sorrell, T., Li, R., Jiang, W., Chen, S., Xu, Y. (2013). Practical identification of eight medically important Trichosporon species by reverse line blot hybridization (RLB) assay and rolling circle amplification (RCA). Medical Mycology, 51(3), 300-308. [More Information]

2012

  • Chen, S., Slavin, M., Heath, C., Playford, E., Byth Wilson, K., Marriott, D., Kidd, S., Bak, N., Currie, B., Hajkowicz, K., Meyer, W., Sorrell, T., et al (2012). Clinical Manifestations of Cryptococcus gattii Infection: Determinants of Neurological Sequelae and Death. Clinical Infectious Diseases, 55(6), 789-798. [More Information]
  • McMullan, B., Halliday, C., Sorrell, T., Judd, D., Sleiman, S., Marriott, D., Olma, T., Chen, S. (2012). Clinical Utility of the Cryptococcal Antigen Lateral Flow Assay in a Diagnostic Mycology Laboratory. PLoS One, 7(11), 1-6. [More Information]
  • Aminnejad, M., Diaz, M., Arabatzis, M., Castaneda, E., Lazera, M., Velegraki, A., Marriott, D., Sorrell, T., Meyer, W. (2012). Identification of Novel Hybrids Between Cryptococcus neoformans var.grubii VNI and Cryptococcus gattii VGII. Mycopathologia, 173(5-6), 337-346. [More Information]
  • Lev, S., Desmarini, D., Chayakulkeeree, M., Sorrell, T., Djordjevic, J. (2012). The Crz1/Sp1 Transcription Factor of Cryptococcus neoformans Is Activated by Calcineurin and Regulates Cell Wall Integrity. PLoS One, 7(12), 1-13. [More Information]

2011

  • Wang, H., Xiao, M., Kong, F., Chen, S., Dou, H., Sorrell, T., Li, R., Xu, Y. (2011). Accurate and Practical Identification of 20 Fusarium Species by Seven-Locus Sequence Analysis and Reverse Line Blot Hybridization, and an In Vitro Antifungal Susceptibility Study. Journal of Clinical Microbiology, 49(5), 1890-1898. [More Information]
  • Widmer, A., Sorrell, T., Wright, L., Jolliffe, K. (2011). Patent Family: Bis-cationic compounds and use thereof. Patent No. 2004289375, 7947854.
  • Ngamskulrungroj, P., Price, J., Sorrell, T., Perfect, J., Meyer, W. (2011). Cryptococcus Gattii Virulence Composite: Candidate Genes Revealed by Microarray Analysis of High and Less Virulent Vancouver Island Outbreak Strains. PLoS One, 6(1), e16076 - 1-e16076 - 12. [More Information]
  • Morrissey, C., Chen, S., Sorrell, T., Bradstock, K., Szer, J., Halliday, C., Gilroy, N., Schwarer, A., Slavin, M. (2011). Design issues in a randomized controlled trial of a pre-emptive versus empiric antifungal strategy for invasive aspergillosis in patients with high-risk hematologic malignancies. Leukemia and Lymphoma, 52(2), 179-193. [More Information]
  • Konstantinos, A., Simpson, G., Sorrell, T., Marais, B. (2011). Doing the right thing for tuberculosis control in the Torres Strait Islands. Medical Journal of Australia, 195(9), 512-512. [More Information]
  • Chen, S., Slavin, M., Sorrell, T. (2011). Echinocandin Antifungal Drugs in Fungal Infections A Comparison. Drugs, 71(1), 11-41. [More Information]
  • Ferguson, P., Gilroy, N., Sloots, T., Nissen, M., Dwyer, D., Sorrell, T. (2011). Evaluation of a clinical scoring system and directed laboratory testing for respiratory virus infection in hematopoietic stem cell transplant recipients. Transplant Infectious Disease (Print), 13(5), 448-455. [More Information]
  • Wang, T., Kong, F., Chen, S., Xiao, M., Sorrell, T., Wang, X., Wang, S., Sintchenko, V. (2011). Improved identification of Gordonia, Rhodococcus and Tsukamurella species by 5'-end 16S rRNA gene sequencing. Pathology, 43(1), 58-63. [More Information]
  • Zuo, X., Djordjevic, J., Oei Bijosono, J., Desmarini, D., Schibeci, S., Jolliffe, K., Sorrell, T. (2011). Miltefosine Induces Apoptosis-Like Cell Death in Yeast via Cox9p in Cytochrome c Oxidase. Molecular Pharmacology, 80(3), 476-485. [More Information]
  • Outhred, A., Watts, M., Chen, S., Sorrell, T. (2011). Nocardia infections of the face and neck. Current Infectious Disease Reports, 13(2), 132-140. [More Information]
  • Chen, S., Blyth, C., Sorrell, T., Slavin, M. (2011). Pneumonia and Lung Infections due to Emerging and Unusual Fungal Pathogens. Seminars in Respiratory and Critical Care Medicine, 32(6), 703-716. [More Information]
  • Chayakulkeeree, M., Johnston, S., Oei Bijosono, J., Lev, S., Williamson, P., Wilson, C., Zuo, X., Leal, A., Vainstein, M., Meyer, W., Sorrell, T., Djordjevic, J., et al (2011). SEC14 is a specific requirement for secretion of phospholipase B1 and pathogenicity of Cryptococcus neoformans. Molecular Microbiology, 80(4), 1088-1101. [More Information]
  • Fox, D., Djordjevic, J., Sorrell, T. (2011). Signaling Cascades and Enzymes as Cryptococcus Virulence Factors. In J. Heitman, T Kozel, K. Kwon-Chung, J. Perfect & A. Casadevall (Eds.), Cryptococcus: From Human Pathogen to Model Yeast, (pp. 217-234). Washington, United States of America: ASM Press.
  • Blyth, C., Gomes, L., Sorrell, T., da Cruz, M., Sud, A., Chen, S. (2011). Skull-base osteomyelitis: Fungal vs. bacterial infection. Clinical Microbiology and Infection, 17(2), 306-311. [More Information]
  • Guo, L., Xiao, M., Kong, F., Chen, S., Wang, H., Sorrell, T., Jiang, W., Dou, H., Li, R., Xu, Y. (2011). Three-locus identification, genotyping, and antifungal susceptibilities of medically important Trichosporon species from China. Journal of Clinical Microbiology, 49(11), 3805-3811. [More Information]

2010

  • Chen, S., Playford, E., Sorrell, T. (2010). Antifungal therapy in invasive fungal infections. Current Opinion in Pharmacology, 10(5), 522-30. [More Information]
  • Slavin, M., Sorrell, T., Marriott, D., Thursky, K., Nguyen, Q., Ellis, D., Morrissey, C., Chen, S. (2010). Candidaemia in adult cancer patients: risks for fluconazole-resistant isolates and death. Journal of Antimicrobial Chemotherapy, 65(5), 1042-1051. [More Information]
  • Blyth, C., Middleton, P., Harun, A., Sorrell, T., Meyer, W., Chen, S. (2010). Clinical associations and prevalence of Scedosporium spp. in Australian cystic fibrosis patients: identification of novel risk factors? Medical Mycology, 48(1), S37-S44. [More Information]
  • Perfect, J., Dismukes, W., Dromer, F., Goldman, D., Nguyen, M., Pappas, P., Powderly, W., Singh, N., Sobel, J., Sorrell, T., et al (2010). Clinical practice guidelines for the management of cryptococcal disease: 2010 update by the Infectious Diseases Society of America. Clinical Infectious Diseases, 50(3), 291-322. [More Information]
  • Lau, A., Halliday, C., Chen, S., Playford, E., Stanley, K., Sorrell, T. (2010). Comparison of Whole Blood, Serum and Plasma for Early Detection of Candidemia by Multiplex-Tandem PCR. Journal of Clinical Microbiology, 48(3), 811-816. [More Information]
  • Blyth, C., Harun, A., Middleton, P., Sleiman, S., Lee, O., Sorrell, T., Meyer, W., Chen, S. (2010). Detection of Occult Scedosporium Species in Respiratory Tract Specimens from Patients with Cystic Fibrosis by Use of Selective Media. Journal of Clinical Microbiology, 48(1), 314-316. [More Information]
  • Hale, K., Shaw, P., Dalla-Pozza, L., MacIntyre, C., Isaacs, D., Sorrell, T. (2010). Epidemiology of paediatric invasive fungal infections and a case-control study of risk factors in acute leukaemia or post stem cell transplant. British Journal of Haematology, 149(2), 263-272. [More Information]
  • Sorrell, T., Djordjevic, J., Jolliffe, K. (2010). Fungal phospholipid metabolism forantifungal drug discovery. Microbiology Australia, 31, 93-94.
  • Xiao, M., Kong, F., Sorrell, T., Cao, Y., Lee, O., Liu, Y., Sintchenko, V., Chen, S. (2010). Identification of Pathogenic Nocardia Species by Reverse Line Blot Hybridization Targeting the 16S rRNA and 16S-23S rRNA Gene Spacer Regions. Journal of Clinical Microbiology, 48(2), 503-511. [More Information]
  • Chen, S., Biswas, C., Bartley, R., Widmer, A., Pantarat, N., Obando Gutierrez, D., Djordjevic, J., Ellis, D., Jolliffe, K., Sorrell, T. (2010). In vitro antifungal activities of bis(alkylpyridinium)alkane compounds against pathogenic yeasts and molds. Antimicrobial Agents and Chemotherapy, 54(8), 3233-3240. [More Information]
  • Playford, E., Nimmo, G., Tilse, M., Sorrell, T. (2010). Increasing incidence of candidaemia: long-term epidemiological trends, Queensland, Australia, 1999-2008. Journal of hospital infection, 76(1), 46-51. [More Information]
  • Gilbert, N., Donlin, M., Gerik, K., Specht, C., Djordjevic, J., Wilson, C., Sorrell, T., Lodge, J. (2010). KRE genes are required for beta-1,6-glucan synthesis, maintenance of capsule architecture and cell wall protein anchoring in Cryptococcus neoformans. Molecular Microbiology, 76(2), 517-534. [More Information]
  • Playford, E., Lipman, J., Sorrell, T. (2010). Management of invasive candidiasis in the intensive care unit. Drugs, 70(7), 823-839. [More Information]
  • Krockenberger, M., Malik, R., Ngamskulrungroj, P., Trilles, L., Escandon, P., Dowd, S., Allen, C., Himmelreich, U., Canfield, P., Sorrell, T., Meyer, W. (2010). Pathogenesis of pulmonary Cryptococcus gattii Infection: A Rat model. Mycopathologia, 170(5), 315-330. [More Information]
  • Playford, E., Lipman, J., Sorrell, T. (2010). Prophylaxis, empirical and preemptive treatment of invasive candidiasis. Current Opinion in Critical Care, 16(5), 470-474. [More Information]
  • Sorrell, T., Chen, S. (2010). Recent advances in management of cryptococcal meningitis: commentary. F1000 Medicine Reports, 2, 82. [More Information]
  • Wang, X., Xiao, M., Kong, F., Sintchenko, V., Wang, H., Wang, B., Lian, S., Sorrell, T., Chen, S. (2010). Reverse line blot hybridization and DNA sequencing studies of the 16S-23S rRNA gene intergenic spacer regions of five emerging pathogenic Nocardia species. Journal of Medical Microbiology, 59(Pt 5), 548-555. [More Information]
  • Kong, F., Wang, H., Zhang, E., Sintchenko, V., Xiao, M., Sorrell, T., Chen, X., Chen, S. (2010). SecA1 Gene Sequence Polymorphisms for Species Identification of Nocardia and Recognition of Intraspecies Genetic Diversity. Journal of Clinical Microbiology, 48(11), 3928-3934. [More Information]
  • Blyth, C., Gomes, L., Sorrell, T., da Cruz, M., Sud, A., Chen, S. (2010). Skull-base osteomyelitis: fungal versus bacterial infection. Clinical Microbiology and Infection, DOI: 10.1111/j.1469-0691.2010.03231.x, 1-6. [More Information]
  • Bialasiewicz, S., Rockett, R., Whiley, D., Abed, Y., Allander, T., Binks, M., Boivin, G., Cheng, A., Chung, J., Gilroy, N., Sorrell, T., et al (2010). Whole Genome Characterisation and Genotyping of Global WU Polyomavirus Strains. Journal of Virology, 84(12), 6229-34. [More Information]

2009

  • Playford, E., Lipman, J., Kabir, M., McBryde, E., Nimmo, G., Lau, A., Sorrell, T. (2009). Assessment of clinical risk predictive rules for invasive candidiasis in a prospective multicentre cohort of ICU patients. Intensive Care Medicine, 35(12), 2141-2145. [More Information]
  • Kong, F., Chen, S., Chen, X., Sintchenko, V., Halliday, C., Cai, L., Tong, Z., Lee, O., Sorrell, T. (2009). Assignment of Reference 5’-end 16S rDNA Sequences and Species-Specific Sequence Polymorphisms Improves Species Identification of Nocardia. The Open Microbiology Journal, 3, 97-105. [More Information]
  • Brown, G., Sorrell, T. (2009). Building quality in health--the need for clinical researchers. Medical Journal of Australia, 190(11), 627-629. [More Information]
  • Chen, S., Marriott, D., Playford, E., Nguyen, Q., Ellis, D., Meyer, W., Sorrell, T., Slavin, M. (2009). Candidaemia with uncommon Candida species: Predisposing factors, outcome, antifungal susceptibility, and implications for management. Clinical Microbiology and Infection, 15(7), 662-669. [More Information]
  • van Hal, S., Marriott, D., Chen, S., Nguyen, Q., Sorrell, T., Ellis, D., Slavin, M. (2009). Candidemia following solid organ transplantation in the era of antifungal prophylaxis: the Australian experience. Transplant Infectious Disease (Print), 11(2), 122-127. [More Information]
  • Gordon-Thomson, C., Kumari, A., Tomkins, L., Holford, P., Djordjevic, J., Wright, L., Sorrell, T., Moore, G. (2009). Chitotriosidase and gene therapy for fungal infections. Cellular and Molecular Life Sciences, 66(6), 1116-1125. [More Information]
  • Lau, A., Chen, S., Sleiman, S., Sorrell, T. (2009). Current status and future perspectives on molecular and serological methods in diagnostic mycology. Future Microbiology, 4(9), 1185-1222. [More Information]
  • Marriott, D., Playford, E., Chen, S., Slavin, M., Nguyen, Q., Ellis, D., Sorrell, T. (2009). Determinants of mortality in non-neutropenic ICU patients with candidaemia. Critical Care, 13(4), 1-8. [More Information]
  • Sorrell, T., Chen, S. (2009). Fungal-derived immune modulating molecules. Advances in Experimental Medicine and Biology, 666, 108-120.
  • Blyth, C., Chen, S., Slavin, M., Serena, C., Nguyen, Q., Marriott, D., Ellis, D., Meyer, W., Sorrell, T. (2009). Not just little adults: candidemia epidemiology, molecular characterization, and antifungal susceptibility in neonatal and pediatric patients. Pediatrics (English Edition), 123(5), 1360-1368. [More Information]
  • Heath, C., Slavin, M., Sorrell, T., Handke, R., Harun, A., Phillips, M., Nguyen, Q., Delhaes, L., Ellis, D., Meyer, W., Chen, S., et al (2009). Population-based surveillance for scedosporiosis in Australia: Epidemiology, disease manifestations and emergence of Scedosporium aurantiacum infection. Clinical Microbiology and Infection, 15(7), 689-693. [More Information]
  • Wang, H., Kong, F., Sorrell, T., Wang, B., McNicholas, P., Pantarat, N., Ellis, D., Xiao, M., Widmer, A., Chen, S. (2009). Rapid detection of ERG11 gene mutations in clinical Candida albicans isolates with reduced susceptibility to fluconazole by rolling circle amplification and DNA sequencing. BMC Microbiology, 9, 167-1-167-12. [More Information]
  • Himmelreich, U., Malik, R., Kuhn, T., Daniel, H., Somorjai, R., Dolenko, B., Sorrell, T. (2009). Rapid Etiological Classification of Meningitis by NMR Spectroscopy Based on Metabolite Profiles and Host Response. PLoS One, 4(4), e5328-1-e5328-8. [More Information]
  • Kesson, A., Bellemore, M., O'Mara, T., Ellis, D., Sorrell, T. (2009). Scedosporium prolificans osteomyelitis in an immunocompetent child treated with a novel agent, hexadecylphospocholine (miltefosine), in combination with terbinafine and voriconazole: a case report. Clinical Infectious Diseases, 48(9), 1257. [More Information]
  • Obando Gutierrez, D., Pantarat, N., Handke, R., Koda, Y., Widmer, A., Djordjevic, J., Ellis, D., Sorrell, T., Jolliffe, K. (2009). Synthesis, antifungal, haemolytic and cytotoxic activities of a series of bis(alkylpyridinium)alkanes. Bioorganic and Medicinal Chemistry, 17(17), 6329-6339. [More Information]

2008

  • Ngamskulrungroj, P., Sorrell, T., Chindamporn, A., Poonwan, N., Chaiprasert, A., Meyer, W. (2008). Association between fertility and molecular sub-type of global isolates of Cryptococcus gattii molecular type VGII. Medical Mycology, 46(7), 655-673. [More Information]
  • Playford, E., Marriott, D., Nguyen, Q., Chen, S., Ellis, D., Slavin, M., Sorrell, T. (2008). Candidemia in nonneutropenic critically ill patients: Risk factors for non-albicans Candida spp. Critical Care Medicine, 36(7), 2034-2039. [More Information]
  • Chen, S., Tong, Z., Lee, O., Halliday, C., Playford, E., Widmer, A., Kong, F., Wu, C., Sorrell, T. (2008). Clinician response to Candida organisms in the urine of patients attending hospital. European Journal of Clinical Microbiology and Infectious Diseases, 27(3), 201-208. [More Information]
  • Lau, A., Sorrell, T., Lee, O., Stanley, K., Halliday, C. (2008). Colony Multiplex-Tandem PCR for Rapid, Accurate Identification of Fungal Cultures. Journal of Clinical Microbiology, 46(12), 4058-4060. [More Information]
  • Delhaes, L., Harun, A., Chen, S., Nguyen, Q., Slavin, M., Heath, C., Maszewska, K., Halliday, C., Robert, V., Sorrell, T., Meyer, W., et al (2008). Molecular typing of Australian Scedosporium isolates showing genetic variability and numerous S. aurantiacum. Emerging Infectious Diseases, 14(2), 282-290. [More Information]
  • Lau, A., Sorrell, T., Chen, S., Stanley, K., Iredell, J., Halliday, C. (2008). Multiplex-Tandem PCR: A Novel Platform for the Rapid Detection and Identification of Fungal Pathogens from Blood Culture Specimens. Journal of Clinical Microbiology, 46(9), 3021-3027. [More Information]
  • Sorrell, T., Himmelreich, U. (2008). NMR in mycology. Current Fungal Infection Reports, 2, 149-156.
  • Krockenberger, M., Malik, R., Ngamskulrungroj, P., Dowd, S., Meyer, W., Sorrell, T. (2008). Pathogenesis of Cryptococcosis caused by Cryptococcus gattii in a Rat Model of Disease. 7th International Conference on Cryptococcus and Cryptococcosis 2008.
  • Zhou, X., Kong, F., Sorrell, T., Wang, H., Duan, Y., Chen, S. (2008). Practical method for detection and identification of Candida, Aspergillus and Scedosporium using rolling circle amplification (RCA). Journal of Clinical Microbiology, 46(7), 2423-2427. [More Information]
  • Kong, F., Tong, Z., Chen, X., Sorrell, T., Wang, B., Wu, Q., Ellis, D., Chen, S. (2008). Rapid identification and differentiation of Trichophyton species, based on sequence polymorphisms of the ribosomal internal transcribed spacer regions, by rolling-circle amplification. Journal of Clinical Microbiology, 46(4), 1192-1199. [More Information]
  • Branley, J., Roy, B., Dwyer, D., Sorrell, T. (2008). Real-time PCR detection and quantitation of Chlamydophila psittaci in human and avian specimens from a veterinary clinic cluster. European Journal of Clinical Microbiology and Infectious Diseases, 27(4), 269-273. [More Information]
  • Thursky, K., Playford, E., Seymour, J., Sorrell, T., Ellis, D., Guy, S., Gilroy, N., Chu, J., Shaw, D. (2008). Recommendations for the treatment of established fungal infections. Internal Medicine Journal, 38(6B), 496-520. [More Information]
  • De Pauw, B., Walsh, T., Donnelly, J., Stevens, D., Edwards, J., Calandra, T., Pappas, P., Maertens, J., Lortholary, O., Sorrell, T., et al (2008). Revised definitions of Invasive fungal disease from the European Organisation for Research and treatmentof Cancer. Clinical Infectious Diseases, 46(12), 1813-1821. [More Information]
  • Chayakulkeeree, M., Sorrell, T., Siafakas, A., Wilson, C., Pantarat, N., Gerik, K., Boadle, R., Djordjevic, J. (2008). Role and mechanism of phosphatidylinositol-specific phospholipase C in survival and virulence of Cryptococcus neoformans. Molecular Microbiology, 69(4), 809-826. [More Information]

2007

  • Chen, S., Sorrell, T. (2007). Antifungal agents. Medical Journal of Australia, 187(7), 404-409. [More Information]
  • Siafakas, A., Sorrell, T., Wright, L., Wilson, C., Larsen, M., Boadle, R., Williamson, P., Djordjevic, J. (2007). Cell wall-linked cryptococcal phospholipase B1 is a source of secreted enzyme and a determinant of cell wall integrity. Journal of Biological Chemistry, 282(52), 37508-37514. [More Information]
  • Wu, Q., Chen, S., Santangelo, R., Martin, P., Malik, R., Sorrell, T. (2007). Cryptococcal phospholipase B antigen is not detected in serum of patients infected with Cryptococcus neoformans using a sandwich enzyme-linked immunosorbent assay. FEMS Yeast Research, 7(3), 465-470. [More Information]
  • Sorrell, T. (2007). Detection of Fungal Metabolites. In Johan A Maertens and Kieren A. Marr (Eds.), Diagnosis of Fungal Infections, (pp. 121-132). New York: Informa Healthcare.
  • Plummer, R., Bodkin, J., Power, D., Pantarat, N., Bubb, W., Kuchel, P., Sorrell, T. (2007). Effect of caspofungin on metabolite profiles of Aspergillus species determined by nuclear magnetic resonance spectroscopy. Antimicrobial Agents and Chemotherapy, 51(11), 4077-4084. [More Information]
  • Tong, Z., Widmer, A., Sorrell, T., Guse, Z., Jolliffe, K., Halliday, C., Lee, O., Kong, F., Wright, L., Chen, S. (2007). In Vitro Activities of Miltefosine and Two Novel Antifungal Biscationic Salts against a Panel of 77 Dermatophytes. Antimicrobial Agents and Chemotherapy, 51(6), 2219-2222. [More Information]
  • Carter, E., Marshall, C., Ali, M., Ganendren, R., Sorrell, T., Wright, L., Lee, Y., Chen, C., Lay, P. (2007). Infrared Spectroscopy of Microorganisms: Characterization, Identification, and Differentiation. In Katrin Kneipp, Ricardo Aroca, Harald Kneipp and Edeline Wentrup-Byrne (Eds.), New Approaches in Biomedical Spectroscopy, (pp. 64-84). Washington DC, United States: American Chemical Society.
  • Plummer, R., Bodkin, J., Yau, T., Power, D., Pantarat, N., Larkin, T., Szekely, D., Bubb, W., Sorrell, T., Kuchel, P. (2007). Modelling Staphylococcus aureus-induced septicemia using NMR. Magnetic Resonance in Medicine, 58(4), 656-665. [More Information]
  • Zeng, X., Kong, F., Halliday, C., Chen, S., Lau, A., Playford, E., Sorrell, T. (2007). Reverse line blot (RLB) hybridization assay for the identification of medically important fungi from culture and clinical specimens. Journal of Clinical Microbiology, , 1-40. [More Information]
  • Jones, P., Turner, K., Djordjevic, J., Sorrell, T., Wright, L., George, A. (2007). Role of Conserved Active Site Residues in Catalysis by Phospholipase B1 from Cryptococcus neoformans. Biochemistry, 46(35), 10024-10032. [More Information]
  • Obando Gutierrez, D., Widmer, A., Wright, L., Sorrell, T., Jolliffe, K. (2007). Synthesis, antifungal and antimicrobial activity of alkylphospholipids. Bioorganic and Medicinal Chemistry, 15(15), 5158-5165. [More Information]
  • Ng, C., Singhal, V., Widmer, A., Wright, L., Sorrell, T., Jolliffe, K. (2007). Synthesis, antifungal and haemolytic activity of a series of bis(pyridinium)alkanes. Bioorganic and Medicinal Chemistry, 15(10), 3422-3429. [More Information]

2006

  • Chen, S., Slavin, M., Nguyen, Q., Marriott, D., Playford, E., Ellis, D., Sorrell, T. (2006). Active surveillance for candidemia, Australia. Emerging Infectious Diseases, 12(10). [More Information]
  • Playford, E., Webster, A., Sorrell, T., Craig, J. (2006). Antifungal agents for preventing fungal infections in non-neutropenic critically ill and surgical patients: systematic review and meta-analysis of randomized clinical trials. Journal of Antimicrobial Chemotherapy. [More Information]
  • Playford, E., Webster, A., Sorrell, T., Craig, J. (2006). Antifungal agents for preventing fungal infections in non-neutropenic critically ill patients. Cochrane Database of Systematic Reviews, 1(1), CD004920. [More Information]
  • Coen, M., Bodkin, J., Power, D., Bubb, W., Himmelreich, U., Kuchel, P., Sorrell, T. (2006). Antifungal effects on metabolite profiles of medically important yeast species measured by nuclear magnetic resonance spectroscopy. Antimicrobial Agents and Chemotherapy, 50(12), 4018-4026. [More Information]
  • Sorrell, T., Wright, L., Malik, R., Himmelreich, U. (2006). Application of proton nuclear magnetic resonance spectroscopy to the study of Cryptococcus and cryptococcosis. FEMS Yeast Research, 6(4), 558-566.
  • Marriott, D., Playford, D., Nguyen, Q., Chen, S., Ellis, D., Slavin, M., Sorrell, T. (2006). Candidaemia in the Australian intensive care unit: Epidemiology, clinical features and outcome from a 3 year nationwide study. Australian Candidaemia Study, Australia: Elsevier.
  • Anaissie, E., Segal, B., Graybill, J., Arndt, C., Perfect, J., Kleinberg, M., Pappas, P., Benjamin, D., Rubin, M., Sorrell, T., et al (2006). Clinical research in the lay press: irresponsible journalism raises a huge dose of doubt. Clinical Infectious Diseases, 43(8), 1031-1039.
  • Ng, C., Obando Gutierrez, D., Widmer, A., Wright, L., Sorrell, T., Jolliffe, K. (2006). Correlation of antifungal activity with fungal phospholipase inhibition using a series of bisquaternary ammonium salts. Journal of Medicinal Chemistry, 49(2), 811-816. [More Information]
  • Wright, L., Santangelo, R., Ganendren, R., Payne, J., Djordjevic, J., Sorrell, T. (2006). Cryptococcal lipid metabolism: phospholipase B1 is implicated in transcellular metabolism of macrophage-derived lipids. Eukaryotic Cell, 6(1), 37-47. [More Information]
  • Lau, A., Chen, S., Sorrell, T., Carter, D., Malik, R., Martin, P., Halliday, C. (2006). Development and clinical application of a panfungal PCR assay to detect and identify fungal DNA in tissue specimens. Journal of Clinical Microbiology, (doi:10.1128/JCM.01862-06) 45 (2)(45 (2)), 380-385. [More Information]
  • Widmer, A., Wright, L., Obando Gutierrez, D., Handke, R., Ganendren, R., Ellis, D., Sorrell, T. (2006). Hexadecylphosphocholine (miltefosine) has broad-spectrum fungicidal activity and is efficacious in a mouse model of cryptococcosis. Antimicrobial Agents and Chemotherapy, 50(2), 414-421. [More Information]
  • Siafakas, A., Wright, L., Sorrell, T., Djordjevic, J. (2006). Lipid rafts in Cryptococcus neoformans concentrate the virulence determinants phospholipase B1 and Cu/Zn superoxide dismutase. Eukaryotic Cell, 5(3), 488-498. [More Information]
  • Turner, K., Wright, L., Sorrell, T., Djordjevic, J. (2006). N-linked glycosylation sites affect secretion of cryptococcal phospholipase B1, irrespective of glycosylphosphatidylinositol anchoring. BBA - Bioenergetics, 1760 (10), 1569-1579. [More Information]
  • Ganendren, R., Carter, E., Sorrell, T., Widmer, A., Wright, L. (2006). Phospholipase B activity enhances adhesion of Cryptococcus neoformans to a human lung epithelial cell line. Microbes and Infection, 8(4), 1006-1015. [More Information]
  • Halliday, C., Hoile, R., Sorrell, T., James, G., Yadav, S., Shaw, P., Bleakley, M., Bradstock, K., Chen, S. (2006). Role of prospective screening of blood for invasive aspergillosis by polymerase chain reaction in febrile neutropenic recipients of haematopoietic stem cell transplants and patients with acute leukaemia. British Journal of Haematology, 132(4), 478-486. [More Information]
  • Playford, E., Kong, F., Sun, Y., Wang, H., Halliday, C., Sorrell, T. (2006). Simultaneous detection and identification of Candida, Aspergillus, and Cryptococcus species by reverse line blot hybridization. Journal of Clinical Microbiology, 44(3), 876-880. [More Information]
  • Playford, E., Webster, A., Sorrell, T., Craig, J. (2006). Systematic review and meta-analysis of antifungal agents for preventing fungal infections in liver transplant recipients. European Journal of Clinical Microbiology and Infectious Diseases, 25(9), 549-561. [More Information]
  • Sorrell, T., Lonsdale, C. (2006). Urgent strategic research into influenza to inform health policy and protect the public. Medical Journal of Australia, 185(10), S77-S79. [More Information]

2005

  • Himmelreich, U., Somorjai, R., Dolenko, B., Daniel, H., Sorrell, T. (2005). A rapid screening test to distinguish between Candida albicans and Candida dubliniensis using NMR spectroscopy. FEMS Microbiology Letters, 251(2), 327-32. [More Information]
  • Santangelo, R., Chen, S., Sorrell, T., Wright, L. (2005). Detection of antibodies to phospholipase B in patients infected with Cryptococcus neoformans by enzyme-linked immunosorbent assay (ELISA). Medical Mycology, 43(4), 335-341. [More Information]
  • Halliday, C., Wu, Q., James, G., Sorrell, T. (2005). Development of a Nested Qualitative Real-Time PCR Assay To Detect Aspergillus Species DNA in Clinical Specimens. Journal of Clinical Microbiology, 43(10), 5366-5368. [More Information]
  • Dzendrowskyj, T., Dolenko, B., Sorrell, T., Somorjai, R., Malik, R., Mountford, C., Himmelreich, U. (2005). Diagnosis of cerebral cryptococcoma using a computerized analysis of 1H NMR spectra in an animal model. Diagnostic microbiology and infectious disease, 52(2), 101-5. [More Information]
  • Himmelreich, U., Accurso, R., Malik, R., Dolenko, B., Somorjai, R., Gupta, R., Gomes, L., Mountford, C., Sorrell, T. (2005). Identification of Staphylococcus aureus brain abscesses: rat and human studies with 1H MR spectroscopy. Radiology, 236(1), 261-70. [More Information]
  • Jones, P., Sorrell, T. (2005). Infections in the immunocompromised host. In Allen Yung, M McDonald, D Spelman, A Street, P Johnson, T Sorrell, J McCormack (Eds.), Infectious Diseases: A clinical approach, (pp. 412-420). Melbourne: IP Communications.
  • Sorrell, T., Mitchell, D., Iredell, J. (2005). Nocardia Species. In Gerald L. Mandell, MD, MACP, John E. Bennett, MD and Raphael Dolin, MD (Eds.), Principles and Practice of Infectious Diseases, (pp. 2916-2924). UK: Churchill Livingstone.
  • Coen, M., O'Sullivan, M., Bubb, W., Kuchel, P., Sorrell, T. (2005). Proton nuclear magnetic resonance-based metabonomics for rapid diagnosis of meningitis and ventriculitis. Clinical Infectious Diseases, 41(11), 1582-1590. [More Information]
  • Yung, A., Stanley, P., Sorrell, T. (2005). Pyrexia of unknown origin. In Allen Yung, M McDonald, D Spelman, A Street, P Johnson, T Sorrell, J McCormack (Eds.), Infectious Diseases: A clinical approach, (pp. 75-88). Melbourne: IP Communications.
  • Djordjevic, J., Del Poeta, M., Sorrell, T., Turner, K., Wright, L. (2005). Secretion of cryptococcal phospholipase B1 (PLB1) is regulated by a glycosylphosphatidylinositol (GPI) anchor. Biochemical Journal, 389(Part 3), 803-812. [More Information]
  • Iredell, J., Spelman, D., Sorrell, T. (2005). Septicaemia. In Allen Yung, M McDonald, D Spelman, A Street, P Johnson, T Sorrell, J McCormack (Eds.), Infectious Diseases: A clinical approach, (pp. 183-193). Melbourne: IP Communications.

2004

  • Wright, L., Payne, J., Santangelo, R., Simpanya, M., Chen, S., Widmer, A., Sorrell, T. (2004). Cryptococcal Phospholipases: A Novel Lysophospholipase Discovered In The Pathogenic Fungus Cryptococcus Gattii. Biochemical Journal, 384(2), 377-384.
  • Slavin, M., Szer, J., Grigg, A., Roberts, A., Seymour, J., Sasadeusz, J., Thursky, K., Chen, S., Morrissey, C., Heath, C., Sorrell, T. (2004). Guidelines for the use of antifungal agents in the treatment of invasive Candida and mould infections. Internal Medicine Journal, 34, 192-200.
  • Ganendren, R., Widmer, A., Singhal, V., Wilson, C., Sorrell, T., Wright, L. (2004). In Vitro Antifungal Activity of Inhibitors of Phospholipases from the Fungal Pathogen Cryptococcus neoformans. Antimicrobial Agents and Chemotherapy, 48(5), 1561-1569.
  • Chang, Y., Wright, L., Tscharke, R., Sorrell, T., Wilson, C., Kwong-Chung, K. (2004). Regulatory Roles For The Homeodomain And C2H2 Zinc Finger Regions Of Cryptococcus Neoformans Ste12Alphap. Molecular Microbiology, 53(5), 1385-96.
  • Santangelo, R., Zoellner, H., Sorrell, T., Wilson, C., Bolitho (nee Donald), C., Djordjevic, J., Yi, S., Wright, L. (2004). Role Of Extracellular Phospholipases And Mononuclear Phagocytes In Dissemination Of Cryptococcosis In A Murine Model. Infection and Immunity, 72(4), 2229-2239.
  • Baumgartner, R., Somorjai, R., Bowman, C., Sorrell, T., Mountford, C., Himmelreich, U. (2004). Unsupervised Feature Dimension Reduction For Classification Of Mr Spectra. Magnetic resonance imaging, 22(2), 251-256.

2003

  • Playford, E., Webster, A., Craig, J., Sorrell, T. (2003). Antifungal prophylaxis in critically-ill ICU and surgical patients: A meta-analysis. 43rd ICAAC, American Society for Microbiology.
  • Playford, E., Webster, A., Craig, J., Sorrell, T. (2003). Antifungal prophylaxis in solid organ transplant recipients: A meta-analysis. 43rd ICAAC, American Society for Microbiology.
  • Coe, J., Wilson, C., Sorrell, T., Latouche, G., Wright, L. (2003). Cloning of CnLYS01, a novel extracellular lysophospholipase of the pathogenic fungus cryptococcus neoformans. Gene, 316(1), 67-78.
  • Himmelreich, U., Allen, C., Dowd, S., Malik, R., Shehan, B., Mountford, C., Sorrell, T. (2003). Identification of metabolites of importance in the pathogenesis of pulmonary cryptoccoma using nuclear magnetic resonance spectroscopy. Microbes and Infection, 5(4), 285-290.
  • Kidd, S., Sorrell, T., Meyer, W. (2003). Isolation of two molecualr types of Cryptococcus neoformans var. gattii from insect frass. Medical Mycology, 41(2), 171-176.
  • Latouche, G., Huynh, M., Sorrell, T., Meyer, W. (2003). PCR-restriction fragment length polymorphism analysis of the phospholipase B (PLB1) gene for subtyping of cryptococcus neoformans isolates. Applied and Environmental Microbiology, 69(4), 2080-2086.
  • Himmelreich, U., Somorjai, R., Dolenko, B., Lee, O., Daniel, H., Murray, R., Mountford, C., Sorrell, T. (2003). Rapid identification of Candida Species by Using Nuclear Magnetic Resonance Spectroscopy and a Statistical classification strategy. Applied and Environmental Microbiology, 69(8), 4566-4574.

2002

  • Murray, R., Himmelreich, U., Gomes, L., Ingham, N., Sorrell, T. (2002). Cerebral nocardiosis characterized by Magnetic Resonance Spectroscopy in vivo. Clinical Infectious Diseases, 34, 849-852.
  • Himmelreich, U., Bourne, R., Sorrell, T., Mountford, C., Somorjai, R. (2002). Identification of Cryptococcus neoformans by Magnetic Resonance Spectroscopy. Microbiology Australia, , 31-33.
  • Latouche, G., Sorrell, T., Meyer, W. (2002). Isolation and characterisation of the phospholipase B gene of Cryptococcus neoformans var. gattii. FEMS Yeast Research, 2(4), 551-561.
  • Wright, L., Bubb, W., Davidson, J., Santangelo, R., Krockenberger, M., Himmelreich, U., Sorrell, T. (2002). Metabolites released by Cryptococcus neoformans var. neoformans and var. gattii differentially affect human neutrophil function. Microbes and Infection, 4(14), 1427-1438.
  • Wright, L., Chen, S., Wilson, C., Simpanya, M., Blackstock, R., Cox, G., Murphy, J., Sorrell, T. (2002). Strain-dependent effects of environmental signals on the production of extracellular phospholipase by Cryptococcus neoformans. FEMS Microbiology Letters, 209(2), 175-181.

2001

  • Himmelreich, U., Dzendrowskyj, T., Allen, C., Dowd, S., Malik, R., Shehan, B., Russell, P., Mountford, C., Sorrell, T. (2001). Cryptococcomas distinguished from gliomas with MR spectroscopy: an experimental rat and cell culture study. Radiology, 220, 122-128.
  • Sorrell, T. (2001). Cryptococcus neoformans variety gatti. Medical Mycology, 39, 155-168.
  • Chen, S., Wright, L., Sorrell, T., Cox,, G., McDade, H., Tucker, S., Gottfredsson, M., Leidich, S., Casadevall, A., Ghannoum, M., et al (2001). Extracellular phospholipase activity is a virulence factor for cryptococcus neoformans. Molecular Microbiology, 39, 166-175.
  • Bourne, R., Himmelreich, U., Mountford, C., Sorrell, T., Sharma, A. (2001). Identification of Enterococcus, Streptococcus and Staphylococcus by multivariate analysis of Proton Magnetic Resonance Spectroscopic data from plate cultures. Journal of Clinical Microbiology, 39(8), 2916-2923.
  • Daniel, H., Sorrell, T., Meyer, W. (2001). Partial sequence analysis of the actin gene and its potential for studying the phylogeny of Candida species and their teleomorphs. International Journal of Systematic and Evolutionary Microbiology, 51, 1593-1606.
  • Meyer, W., Sorrell, T., Maszewska, K. (2001). PCR fingerprinting: a convenient molecular tool to distinguish between candida duliniensis and Candida albicans. Medical Mycology, 39, 185-193.

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