Dr Tatiana Tsoutsman

Clinical Senior Lecturer
Medicine, Central Clinical School
Centenary Institute of Cancer Medicine & Cell Biology

Telephone +61 2 9565 6287
Fax +61 2 9565 6101

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Selected grants

2010

  • Key role of connective tissue growth factor (CTGF) in familial cardiomyopathy and heart failure; Semsarian C, Twigg S, Tsoutsman T; National Health and Medical Research Council (NHMRC)/Project Grants.

2008

  • Multiple Mutations in Familial Cardiomyopathy: Cahracterisation and Treatment Studies; Tsoutsman T, Semsarian C; Heart Foundation of Australia/Grants-in-Aid.

Selected publications

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Journals

  • Tsoutsman, T., Wang, X., Garchow, K., Riser, B., Twigg, S., Semsarian, C. (2013). CCN2 plays a key role in extracellular matrix gene expression in severe hypertrophic cardiomyopathy and heart failure. Journal of Molecular and Cellular Cardiology, 62, 164-178. [More Information]
  • Bagnall, R., Tsoutsman, T., Shephard, R., Ritchie, W., Semsarian, C. (2012). Global MicroRNA Profiling of the Mouse Ventricles during Development of Severe Hypertrophic Cardiomyopathy and Heart Failure. PLoS One, 7(9), 1-8. [More Information]
  • Ng, D., Ng, I., Yeap, Y., Badrain, B., Tsoutsman, T., McMullen, J., Semsarian, C., Bogoyevitch, M. (2011). Opposing Actions of Extracellular Signal-Regulated Kinase (ERK) and Signal Transducer and Activator of Transcription 3 (STAT3) in Regulating Microtubule Stabilization during Cardiac Hypertrophy. Journal of Biological Chemistry, 286(2), 1576-1587. [More Information]
  • Boase, N., Rychkov, G., Townley, S., Dinudom, A., Candi, E., Voss, A., Tsoutsman, T., Semsarian, C., Melino, G., Koentgen, F., Cook, D., et al (2011). Respiratory distress and perinatal lethality in Nedd4-2-deficient mice. Nature Communications, 2(1), 1-9. [More Information]
  • Lam, L., Tsoutsman, T., Arthur, J., Semsarian, C. (2010). Differential protein expression profiling of myocardial tissue in a mouse model of hypertrophic cardiomyopathy. Journal of Molecular and Cellular Cardiology, 48(5), 1014-1022. [More Information]
  • Wang, X., McLennan, S., Allen, T., Tsoutsman, T., Semsarian, C., Twigg, S. (2009). Adverse effects of high glucose and free fatty acid on cardiomyocytes are mediated by connective tissue growth factor. American Journal of Physiology: Cell Physiology, 297(6), c1490-c1500. [More Information]
  • Tsoutsman, T., Bagnall, R., Semsarian, C. (2008). Impact of multiple gene mutations in determining the severity of cardiomyopathy and heart failure. Clinical and Experimental Pharmacology and Physiology, 35(11), 1349-1357. [More Information]
  • Tsoutsman, T., Kelly, M., Ng, D., Tan, J., Tu, E., Lien, L., Bogoyevitch, M., Seidman, C., Seidman, J., Semsarian, C. (2008). Severe heart failure and early mortality in a double-mutation mouse model of familial hypertrophic cardiomyopathy. Circulation, 117(14), 1820-1831. [More Information]
  • Nguyen, L., Chung, J., Lam, L., Tsoutsman, T., Semsarian, C. (2006). Abnormal cardiac response to exercise in a murine model of familial hypertrophic cardiomyopathy. International Journal of Cardiology, , 1-4. [More Information]
  • Tsoutsman, T., Lam, L., Semsarian, C. (2006). Genes, calcium and modifying factors in hypertrophic cardiomyopathy. Clinical and Experimental Pharmacology and Physiology, 33, 139-145. [More Information]
  • Tsoutsman, T., Chung, J., Doolan, A., Nguyen, L., Williams, I., Tu, E., Lam, L., Bailey, C., Rasko, J., Allen, D., Semsarian, C. (2006). Molecular insights from a novel cardiac troponin I mouse model of familial hypertrophic cardiomyopathy. Journal of Molecular and Cellular Cardiology, 41(4), 623-632. [More Information]
  • Tsoutsman, T., Chung, J., Doolan, A., Nguyen, L., Williams, I., Tu, E., Lam, L., Rasko, J., Bailey, C., Allen, D., Semsarian, C. (2006). Mouse cardiac troponin I model of hypertrophic cardiomyopathy: Phenotype associated with abnormal calcium handling. Journal of Molecular and Cellular Cardiology, 41(4), 747 (abstract 41)-747.
  • Doolan, A., Tebo, M., Ingles, J., Nguyen, L., Tsoutsman, T., Lam, L., Chiu, C., Chung, J., Weintraub, R., Semsarian, C. (2005). Cardiac troponin I mutations in Australian families with hypertrophic cardiomyopathy: clinical, genetic and functional consequences. Journal of Molecular and Cellular Cardiology, 38(2), 387-93. [More Information]
  • Esteban, L., Tsoutsman, T., Jordan, M., Roach, D., Poulton, L., Brooks, A., Naidenko, O., Sidobre, S., Godfrey, D., Baxter, A. (2003). Genetic control of NKT cell numbers maps to major diabetes and Lupus Loci. Journal of Immunology, 171(6), 2873-2878. [More Information]

2013

  • Tsoutsman, T., Wang, X., Garchow, K., Riser, B., Twigg, S., Semsarian, C. (2013). CCN2 plays a key role in extracellular matrix gene expression in severe hypertrophic cardiomyopathy and heart failure. Journal of Molecular and Cellular Cardiology, 62, 164-178. [More Information]

2012

  • Bagnall, R., Tsoutsman, T., Shephard, R., Ritchie, W., Semsarian, C. (2012). Global MicroRNA Profiling of the Mouse Ventricles during Development of Severe Hypertrophic Cardiomyopathy and Heart Failure. PLoS One, 7(9), 1-8. [More Information]

2011

  • Ng, D., Ng, I., Yeap, Y., Badrain, B., Tsoutsman, T., McMullen, J., Semsarian, C., Bogoyevitch, M. (2011). Opposing Actions of Extracellular Signal-Regulated Kinase (ERK) and Signal Transducer and Activator of Transcription 3 (STAT3) in Regulating Microtubule Stabilization during Cardiac Hypertrophy. Journal of Biological Chemistry, 286(2), 1576-1587. [More Information]
  • Boase, N., Rychkov, G., Townley, S., Dinudom, A., Candi, E., Voss, A., Tsoutsman, T., Semsarian, C., Melino, G., Koentgen, F., Cook, D., et al (2011). Respiratory distress and perinatal lethality in Nedd4-2-deficient mice. Nature Communications, 2(1), 1-9. [More Information]

2010

  • Lam, L., Tsoutsman, T., Arthur, J., Semsarian, C. (2010). Differential protein expression profiling of myocardial tissue in a mouse model of hypertrophic cardiomyopathy. Journal of Molecular and Cellular Cardiology, 48(5), 1014-1022. [More Information]

2009

  • Wang, X., McLennan, S., Allen, T., Tsoutsman, T., Semsarian, C., Twigg, S. (2009). Adverse effects of high glucose and free fatty acid on cardiomyocytes are mediated by connective tissue growth factor. American Journal of Physiology: Cell Physiology, 297(6), c1490-c1500. [More Information]

2008

  • Tsoutsman, T., Bagnall, R., Semsarian, C. (2008). Impact of multiple gene mutations in determining the severity of cardiomyopathy and heart failure. Clinical and Experimental Pharmacology and Physiology, 35(11), 1349-1357. [More Information]
  • Tsoutsman, T., Kelly, M., Ng, D., Tan, J., Tu, E., Lien, L., Bogoyevitch, M., Seidman, C., Seidman, J., Semsarian, C. (2008). Severe heart failure and early mortality in a double-mutation mouse model of familial hypertrophic cardiomyopathy. Circulation, 117(14), 1820-1831. [More Information]

2006

  • Nguyen, L., Chung, J., Lam, L., Tsoutsman, T., Semsarian, C. (2006). Abnormal cardiac response to exercise in a murine model of familial hypertrophic cardiomyopathy. International Journal of Cardiology, , 1-4. [More Information]
  • Tsoutsman, T., Lam, L., Semsarian, C. (2006). Genes, calcium and modifying factors in hypertrophic cardiomyopathy. Clinical and Experimental Pharmacology and Physiology, 33, 139-145. [More Information]
  • Tsoutsman, T., Chung, J., Doolan, A., Nguyen, L., Williams, I., Tu, E., Lam, L., Bailey, C., Rasko, J., Allen, D., Semsarian, C. (2006). Molecular insights from a novel cardiac troponin I mouse model of familial hypertrophic cardiomyopathy. Journal of Molecular and Cellular Cardiology, 41(4), 623-632. [More Information]
  • Tsoutsman, T., Chung, J., Doolan, A., Nguyen, L., Williams, I., Tu, E., Lam, L., Rasko, J., Bailey, C., Allen, D., Semsarian, C. (2006). Mouse cardiac troponin I model of hypertrophic cardiomyopathy: Phenotype associated with abnormal calcium handling. Journal of Molecular and Cellular Cardiology, 41(4), 747 (abstract 41)-747.

2005

  • Doolan, A., Tebo, M., Ingles, J., Nguyen, L., Tsoutsman, T., Lam, L., Chiu, C., Chung, J., Weintraub, R., Semsarian, C. (2005). Cardiac troponin I mutations in Australian families with hypertrophic cardiomyopathy: clinical, genetic and functional consequences. Journal of Molecular and Cellular Cardiology, 38(2), 387-93. [More Information]

2003

  • Esteban, L., Tsoutsman, T., Jordan, M., Roach, D., Poulton, L., Brooks, A., Naidenko, O., Sidobre, S., Godfrey, D., Baxter, A. (2003). Genetic control of NKT cell numbers maps to major diabetes and Lupus Loci. Journal of Immunology, 171(6), 2873-2878. [More Information]

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