Associate Professor Vladimir Balcar

Associate Professor
Anatomy & Histology, School of Medical Sciences
Bosch Institute

Telephone +61 2 9351 2837
Fax +61 2 9552 2026/ 9351 2813

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Research interests

Neurotransmitters in brain

Selected grants

2013

  • The transportome: a coordinate complex regulating brain excitation and inhibition; Pow D, Lee A, Poronnik P, Balcar V; National Health and Medical Research Council (NHMRC)/Project Grants.

2005

  • FACS Aria for the University of Sydney Flow Cytometry Facility; King N, Pollard J, Rasko J, Lovicu F, Bishop A, Bertolino P, Briscoe H, Gillies M, Madigan M, McAvoy J, Murphy C, Balcar V, Armour C, Hughes M, Reeve V, Christopherson R, Halliday G, Christie M, Pollock C, McCaughan G, Gorrell M, Dong Q, Abendroth A, Menzies S, Barnetson R, Byrne S, Hunt N, Hambly B, Cook D, Mason R, Day M, Black J; University of Sydney/Equipment Grant.

2004

  • Distribution and characteristics of excitatory amino acid transporters in the CNS; Balcar V; National Health and Medical Research Council (NHMRC)/Project Grants.

2003

  • The role of deficient glutamate transport in neurodegenerative disease; Balcar V; DVC Research/Bridging Support Grant.
  • Not known; Balcar V; Rebecca L Cooper/Medical Research Foundation.

2002

  • Role of high affinity transport in the metabolism of glutimate; Balcar V; University of Sydney/Medicine Bridging.

2001

  • Role of high affinity transport in the metabolism of synaptic glutamate; Balcar V; Australian Health Management Group/Research Grant.
  • Role of high affinity transport in the metabolism of synaptic glutamate; Balcar V; DVC Research/Bridging Support Grant.

2000

  • The trafficking of glutamate/glutamine in the brain; Rae C, Balcar V; Rebecca L Cooper/Medical Research Foundation.

1999

  • Can the action of n-acetul-l-aspartul-l-glutamate receptors of group II (mGluR II) influence; Balcar V; Clive & Vera Ramaciotti Foundation/Research Grants.

Selected publications

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Book Chapters

  • Stastny, F., Santamaría, A., Pérez-Severiano, F., Galván-Arzate, S., Ríos, C., Balcar, V. (2007). Quinolinic acids and peroxidative brain damage: relevance to schizophrenia (IN PRESS). In Abel Santamaria and Maria Esther Jimenez-Capdeville (Eds.), New Prospectives on Brain Cell Damage, Neurodegeneration and Neuroprotective Strategies, (pp. 113-134). Research Signpost.
  • Stastny, F., Tejkalova, H., Kozmikova-Skuba, I., Balcar, V., Kaiser, M., Yoneda, Y. (2005). Quinolinic acid, NMDA receptor and schizophrenia: Testing an integrative theory. In Yukio Yoneda (Eds.), Amino Acid Signalling 04, (pp. 67-83). India: Research Signpost.
  • Jeffrey, P., Balcar, V., Weinberger, R., Tolhurst, O., Meany, J. (2003). Avian purkinje neuronal cultures: extrinsic control of morphology by cell type and glutamate. In Hollenbeck, Bamburg (Eds.), Methods in Cell Biology: Volume 71: Neurons: Methods and applications for the Cell Biologist, (pp. 91-109). Amsterdam: Academic Press Elsevier. [More Information]

Journals

  • Lochman, J., Balcar, V., Stastny, F., Sery, O. (2013). Preliminary evidence for association between schizophrenia and polymorphisms in the regulatory Regions of the ADRA2A, DRD3 and SNAP-25 Genes. Psychiatry Research, 205(1-2), 7-12. [More Information]
  • Nasrallah, F., Balcar, V., Rae, C. (2011). Activity-dependent γ-aminobutyric acid release controls brain cortical tissue slice metabolism. Journal of Neuroscience Research, 89(12), 1935-1945. [More Information]
  • Sery, O., St'astny, F., Zvolsky, P., Hlinomazova, Z., Balcar, V. (2011). Association between Val66Met polymorphism of Brain-Derived Neurotrophic Factor (BDNF) gene and a deficiency of colour vision in alcohol-dependent male patients. Neuroscience Letters, 499(3), 154-157. [More Information]
  • Nasrallah, F., Balcar, V., Rae, C. (2010). A Metabonomic Study of Inhibition of GABA Uptake in the Cerebral Cortex. Metabolomics, 6(1), 67-77. [More Information]
  • Nguyen, K., Buljan, V., Else, P., Pow, D., Balcar, V. (2010). Cardiac Glycosides Ouabain and Digoxin Interfere with the Regulation of Glutamate Transporter GLAST in Astrocytes Cultured from Neonatal Rat Brain. Neurochemical Research, 35(12), 2062-2069. [More Information]
  • Nasrallah, F., Maher, A., Hanrahan, J., Balcar, V., Rae, C. (2010). Gamma-Hydroxybutyrate and the GABAergic footprint: a metabolomic approach to unpicking the actions of GHB. Journal of Neurochemistry, 115(1), 58-67. [More Information]
  • Shin, J., Nguyen, K., Pow, D., Knight, T., Buljan, V., Bennett, M., Balcar, V. (2009). Distribution of Glutamate Transporter GLAST in Membranes of Cultured Astrocytes in the Presence of Glutamate Transport Substrates and ATP. Neurochemical Research, 34(10), 1758-1766. [More Information]
  • Beart, P., Balcar, V. (2009). Graham Johnston: bringing success to neuroscience through medicinal chemistry. Neurochemical Research, 34, 1696-1697.
  • Rae, C., Nasrallah, F., Griffin, J., Balcar, V. (2009). Now I know my ABC. A systems neurochemistry and functional metabolomic approach to understanding the GABAergic system. Journal of Neurochemistry, 109(Suppl 1), 109-116. [More Information]
  • Nguyen, K., Shin, J., Rae, C., Nanitsos, E., Acosta, G., Powis, D., Buljan, V., Bennett, M., Else, P., Balcar, V. (2009). Rottlerin Inhibits (Na(+), K (+))-ATPase Activity in Brain Tissue and Alters D-Aspartate Dependent Redistribution of Glutamate Transporter GLAST in Cultured Astrocytes. Neurochemical Research, 34(10), 1767-1774. [More Information]
  • Nasrallah, F., Griffin, J., Balcar, V., Rae, C. (2009). Understanding your inhibitions: effects of GABA and GABAA receptor modulation on brain cortical metabolism. Journal of Neurochemistry, 108(1), 57-71. [More Information]
  • Getts, D., Balcar, V., Matsumoto, I., Muller, M., King, N. (2008). Viruses and the immune system: their roles in seizure cascade development. Journal of Neurochemistry, 104(5), 1167-1176. [More Information]
  • Bröer, S., Bröer, A., Hansen, J., Bubb, W., Balcar, V., Nasrallah, F., Garner, B., Rae, C. (2007). Alanine metabolism, transport and cycling in the brain. Journal of Neurochemistry, 102, 1758-1770. [More Information]
  • Nasrallah, F., Griffin, J., Balcar, V., Rae, C. (2007). Understanding your inhibitions. Modulation of brain cortical metabolism by GABAB receptors. Journal of Cerebral Blood Flow and Metabolism, 27, 1510-1520. [More Information]
  • Balcar, V., Nanitsos, E. (2006). Autoradiography of [3H]aspartate and glutamate transport in schizophrenia. Neuropsychopharmacology, 31, 685-686.
  • Stastny, F., Vrajová, M., Tejkalova, H., Peková, S., Mareš, V., Kozmiková, I., Jirásková, J., Höschl, C., Balcar, V. (2006). Composition and function of NMDA receptors in schizophrenia: from animal models to patients. Psychiatrie, 6(Supplement 2), 7-14.
  • El-Hajjmoussa, C., Rae, C., Bubb, W., Griffin, J., Deters, N., Balcar, V. (2006). Inhibitors of glutamate transport modulate distinct patterns in brain metabolism. Journal of Neuroscience Research, 85(2), 342-350. [More Information]
  • Bubenikova-Valesova, V., Balcar, V., Tejkalova, H., Langmeier, M., St’astny, F. (2006). Neonatal administration of N-acetyl-L-aspartyl-L-glutamate induces early neurodegeneration in hippocampus and alters behaviour in young adult rats. Neurochemistry International, 48(6-7), 515-522.
  • Kaiser, M., Mares, V., St’astny, F., Bubenikova-Valesova, V., Lisa, V., Suchomel, P., Balcar, V. (2006). The influence of interleukin-1 beta on gamma-glutamyl transpeptidase activity in rat hippocampus. Physiological Research, 55(4), 461-465.
  • Rae, C., Moussa, C., Griffin, J., Parekh, S., Bubb, W., Hunt, N., Balcar, V. (2005). A metabolomic approach to ionotropic glutamate receptor subtype function: a nuclear magnetic resonance in vitro investigation. Journal of Cerebral Blood Flow and Metabolism, 26(8), 1005-1017. [More Information]
  • Platenik, J., Balcar, V., Yoneda, Y., Mioduszewska, B., Buchal, R., Hynek, R., Kilianek, L., Kuramoto, N., Wilczynski, G., Ogita, K., et al (2005). Apparent presence of Ser133-phosphorylated cyclic AMP response element binding protein (pCREB) in brain mitochondria is due to cross-reactivity of pCREB antibodies with pyruvate dehydrogenase. Journal of Neurochemistry, 95(5), 1446-1460. [More Information]
  • Balcar, V., Nanitsos, E. (2005). Glutamate transport - target for the next generation of neuroleptics? Psychiatrie, 9(Supplement 2), 19-23.
  • Nanitsos, E., Nguyen, K., St’astny, F., Balcar, V. (2005). Glutamatergic hypothesis of schizophrenia: involvement of Na(+)/K(+)-dependent glutamate transport. Journal of Biomedical Science, 12(6), 975-984. [More Information]
  • Rae, C., Moussa, C., Griffin, J., Bubb, W., Wallis, T., Balcar, V. (2005). Group I and II metabotropic glutamate receptors alter brain cortical metabolic and glutamate/glutamine cycle activity: a 13C NMR spectroscopy and metabolomic study. Journal of Neurochemistry, 92(2), 405-416. [More Information]
  • Kuramoto, N., Kubo, K., Ogita, K., Platenik, J., Balcar, V., Takarada, T., Nakamichi, N., Yoneda, Y. (2005). Nuclear Condensation of Cyclic Adenosine Monophosphate Responsive Element-Binding Protein in Discrete Murine Brain Structures. Journal of Neuroscience Research, 80(5), 667-676. [More Information]
  • Kaiser, M., Mareš, V., Sťastný, F., Bubenikova-Valesova, V., Lisá, V., Suchomel, P., Balcar, V. (2005). The influence of interleukin-1beta on gamma-glutamyl transpeptidase activity in rat hippocampus. Physiological Research, 55(4), 461-465. [More Information]
  • Wallis, T., Rae, C., Balcar, V. (2004). Altered nAChR Subunit Expression In The Murine Model Of Duchenne Muscular Dystrophy. Journal of Neurochemistry, 88(1), 80-80.
  • Rae, C., McQuillan, J., Parekh, S., Bubb, W., Weiser, S., Balcar, V., Hansen, A., Ball, H., Hunt, N. (2004). Brain Gene Expression, Metabolism, And Bioenergetics: Interrelationships In Murine Models Of Cerebral And Noncerebral Malaria. The F A S E B Journal, 18(3), 499-510.
  • Nanitsos, E., Acosta, G., Saihara, Y., Stanton, D., Liao, L., Shin, J., Rae, C., Balcar, V. (2004). Effects Of Glutamate Transport Substrates And Glutamate Receptor Ligands On The Activity Of Na+/K+ -ATPase In Brain Tissue In Vitro. Clinical and Experimental Pharmacology and Physiology, 31(11), 762-769.
  • Wallis, T., Bubb, W., McQuillan, J., Balcar, V., Rae, C. (2004). For Want Of A Nail. Ramifications Of A Single Gene Deletion, Dystrophin, In The Brain Of The Mouse. Frontiers in Bioscience, 9(1), 74-84.
  • Nanitsos, E., Rae, C., Bubb, W., Balcar, V. (2004). Glutamate Uptake Is Significantly Increased In The Brain Of The PUFA-Deficient Rat. World Journal of Biological Psychiatry, 5(S1), 118-118.
  • Stastny, F., Tejkalova, H., Kozmikova-Skuba, I., Palenicek, T., Pliss, L., Mares, V., Kristofikova, Z., Kaiser, M., Bubenikova-Valesova, V., Balcar, V. (2004). Interactions Of Dopamine D1/D2 Receptor With Glutamate Receptor Of Nmda Type: From Molecules To Animal Models Of Schizophrenia (In Czech). Psychiatrie, 8(Suppl. 3), 32-41.
  • Takarada, T., Hinoi, E., Balcar, V., Taniura, H., Yoneda, Y. (2004). Possible Expression Of Functional Glutamate Transporters In The Rat Testis. Journal of Endocrinology, 181(2), 233-244.
  • St’astny, F., Lisy, V., Mares, V., Lisa, V., Balcar, V., Santamaria, A. (2004). Quinolinic Acid Induces Nmda Receptor-Mediated Lipid Peroxidation In Rat Brain Microvessels. Redox Report, 9(4), 229-233.
  • Stanton, D., Liao, L., Moussa, C., Bubb, W., Rae, C., Balcar, V. (2003). Can inhibition of glutamate transport contribute to the actions of neuroleptics? Psychiatrie, 7(1), 6-11.
  • Stasny, F., Lisy, V., V, M., Jezova, D., Santamaría, A., Balcar, V. (2003). Functional glutamate resceptors are expressed in rat brain capillary barrier. Psychiatrie, 7(2 suppl), 127-128.
  • Rae, C., Hare, N., Bubb, W., McEwan, S., Broer, A., McQuillan, J., Balcar, V., Conigrave, A., Broer, S. (2003). Inhibition of glutamine transport depletes glutamate and GABA neurotransmitter pools: further evidence for metabolic compartmentation. Journal of Neurochemistry, 85(2), 503-514.
  • Pliss, L., Balcar, V., Bubenikova, V., Pokorny, J., Fitzgibbon, T., Stasny, F. (2003). Morphology and ultrastructure of rat hippocampal formation after i.c.v administration of N-Acetyl-L-Aspartyl-L-Glutamate. Neuroscience, 122(1), 93-101.
  • Bubenikova, V., Balcar, V., Tejkalova, H., Horacek, J., Stastny, F. (2003). Significance of neonatal excitotoxic brain lesions in a neurodevelopmental model of schizophrenia. Psychiatrie, 7(S2), 19-20.
  • Takarada, T., Balcar, V., Baba, K., Takamoto, A., Acosta, G., Takano, K., Yoneda, Y. (2003). Uptake of [3H]L-serine in rat brain synaptosomal fractions. Brain Research, 983, 36-47.
  • St Asny, F., Tejkalova, H., Hoschel, C., Balcar, V. (2003). Viral infection, glutamatergic deficit and behavioural changes in animal model of schizophrenia. Psychiatrie, 7(suppl 2), 128-130.
  • Hinoi, E., Fujimori, S., Kubo, K., Balcar, V., Ogita, K., Yoneda, Y. (2002). Constitutive expression of heterologous N-Methyl-D-aspartate receptor subunits in rat adrenal medulla. Journal of Neuroscience Research, 68(1), 36-45.
  • Takamoto, A., Quiggin, L., Lieb, I., Shave, E., Balcar, V., Yoneda, Y. (2002). Differences between D- and L-aspartate binding to the Na+-dependent binding sites on glutamate transporters in frozen sections of rat brain. Life Sciences, 70(9), 991-1001.
  • El-Hajjmoussa, C., Mitrovic, A., Vandenberg, R., Provis, T., Rae, C., Bubb, W., Balcar, V. (2002). Effects of L-Glutamate Transport Inhibition by a Conformationally Restricted Glutamate Analogue (2S,1’S,2’R)-2-(Carboxycyclopropyl)Glycine (L-CCG III)on Metabolism in Brain Tissue In Vitro Analysed by NMR Spectroscopy. Neurochemical Research, 27, 27-35.
  • Moussa, C., Mitrovic, A., Vandenberg, R., Provis, T., Rae, C., Bubb, W., Balcar, V. (2002). Effects of L-glutamate transport inhibition by a conformationally restricted glutamate analogue (2S,1"S,2'R)-2-(Carboxycyclopropyl) glycine (L-CCF III) on metabolism in brain tissue in vitro analysed by NMR spectroscopy. Neurochemical Research, 27(1), 27-35.
  • Balcar, V. (2002). Molecular pharmacology of the Na+-dependent transport of acidic amino acids in the mammalian central nervous system. Biological and Pharmaceutical Bulletin, 25(3), 291-301.
  • Pliss, L., Jezova, D., Mares, V., Balcar, V., Stastny, F. (2002). N-Acetyl-L-aspartyl-L-glutamate changes functional & structural properties of rat blood-brain barrier. Neuroscience Letters, 317(2), 85-88.
  • Hinoi, E., Balcar, V., Kuramoto, N., Nakamichi, N., Yoneda, Y. (2002). Nuclear transcription factors in the hippocampus. Progress in Neurobiology, 68(2), 145-165.
  • Hirai, T., Kuramoto, N., Maruyama, H., Balcar, V., Nakamura, Y., Yoneda, Y. (2002). Petentiation of Nuclear Activator Protein-1 DNA binding following brief exposure to N-Methly-D-Aspartate in immature cultured rat hippocampal neurons. Journal of Neuroscience Research, 67(4), 523-532.
  • Pliss, L., Bubenikova, V., Balcar, V., Stastny, F. (2001). Characterization of hippocampal neurodegeneration after intracerebroventricular administration of N-acetyl-aspartyl-glutamate. Psychiatrie, 5 (suppl. 2), 102-104.
  • Stastny, F., Pliss, L., Skultétyová, I., Jezova, D., Bubenikova, V., Balcar, V. (2001). NAAG changes properties of blood brain barrier. Psychiatrie, 5 (suppl. 2), 134-136.
  • Balcar, V., Takamoto, A., Yonida,, Y. (2001). Neurochemistry of L-glutamiate transport in the CNS: A review of the thirty years of progress. Collection of Czechoslovak Chemical Communications, 9, 1315-1340.
  • Shave, E., Lawrence, M., Fitzgibbon, T., Balcar, V., Pliss, L., Stastny, F. (2001). Regional distribution and pharmacological characteristics of [3H]N-acetyle-aspartyl-glutamate (NAAG) binding sites in rat brain. Neurochemistry International, 38 (1), 53-62.
  • Balcar, V. (2001). Thirty years of L-glutamate transport in the CNS. Psychiatrie, 5 (suppl. 2), 2-4.

Conferences

  • Kozmikova-Skuba, I., Klaschka, J., Tejkalova, H., Balcar, V., Stastny, F. (2005). Asymetrical hipocampal allocation of NR2 subunits of NMDA receptors in animal model of schizophrenia. Psychiatrie (Prague), Prague: Psychiatrie.
  • Parekh, S., Moussa, C., Balcar, V., Hunt, N., Bubb, W., Rae, C. (2005). Quinolinic acid, kynurenic acid and dserine stimulate brain metabolism. 20th Biennial Meeting of the International Society for Neurochemistry/European Society for Neurochemistry, United Kingdom: Wiley-Blackwell Publishing Ltd.

2013

  • Lochman, J., Balcar, V., Stastny, F., Sery, O. (2013). Preliminary evidence for association between schizophrenia and polymorphisms in the regulatory Regions of the ADRA2A, DRD3 and SNAP-25 Genes. Psychiatry Research, 205(1-2), 7-12. [More Information]

2011

  • Nasrallah, F., Balcar, V., Rae, C. (2011). Activity-dependent γ-aminobutyric acid release controls brain cortical tissue slice metabolism. Journal of Neuroscience Research, 89(12), 1935-1945. [More Information]
  • Sery, O., St'astny, F., Zvolsky, P., Hlinomazova, Z., Balcar, V. (2011). Association between Val66Met polymorphism of Brain-Derived Neurotrophic Factor (BDNF) gene and a deficiency of colour vision in alcohol-dependent male patients. Neuroscience Letters, 499(3), 154-157. [More Information]

2010

  • Nasrallah, F., Balcar, V., Rae, C. (2010). A Metabonomic Study of Inhibition of GABA Uptake in the Cerebral Cortex. Metabolomics, 6(1), 67-77. [More Information]
  • Nguyen, K., Buljan, V., Else, P., Pow, D., Balcar, V. (2010). Cardiac Glycosides Ouabain and Digoxin Interfere with the Regulation of Glutamate Transporter GLAST in Astrocytes Cultured from Neonatal Rat Brain. Neurochemical Research, 35(12), 2062-2069. [More Information]
  • Nasrallah, F., Maher, A., Hanrahan, J., Balcar, V., Rae, C. (2010). Gamma-Hydroxybutyrate and the GABAergic footprint: a metabolomic approach to unpicking the actions of GHB. Journal of Neurochemistry, 115(1), 58-67. [More Information]

2009

  • Shin, J., Nguyen, K., Pow, D., Knight, T., Buljan, V., Bennett, M., Balcar, V. (2009). Distribution of Glutamate Transporter GLAST in Membranes of Cultured Astrocytes in the Presence of Glutamate Transport Substrates and ATP. Neurochemical Research, 34(10), 1758-1766. [More Information]
  • Beart, P., Balcar, V. (2009). Graham Johnston: bringing success to neuroscience through medicinal chemistry. Neurochemical Research, 34, 1696-1697.
  • Rae, C., Nasrallah, F., Griffin, J., Balcar, V. (2009). Now I know my ABC. A systems neurochemistry and functional metabolomic approach to understanding the GABAergic system. Journal of Neurochemistry, 109(Suppl 1), 109-116. [More Information]
  • Nguyen, K., Shin, J., Rae, C., Nanitsos, E., Acosta, G., Powis, D., Buljan, V., Bennett, M., Else, P., Balcar, V. (2009). Rottlerin Inhibits (Na(+), K (+))-ATPase Activity in Brain Tissue and Alters D-Aspartate Dependent Redistribution of Glutamate Transporter GLAST in Cultured Astrocytes. Neurochemical Research, 34(10), 1767-1774. [More Information]
  • Nasrallah, F., Griffin, J., Balcar, V., Rae, C. (2009). Understanding your inhibitions: effects of GABA and GABAA receptor modulation on brain cortical metabolism. Journal of Neurochemistry, 108(1), 57-71. [More Information]

2008

  • Getts, D., Balcar, V., Matsumoto, I., Muller, M., King, N. (2008). Viruses and the immune system: their roles in seizure cascade development. Journal of Neurochemistry, 104(5), 1167-1176. [More Information]

2007

  • Bröer, S., Bröer, A., Hansen, J., Bubb, W., Balcar, V., Nasrallah, F., Garner, B., Rae, C. (2007). Alanine metabolism, transport and cycling in the brain. Journal of Neurochemistry, 102, 1758-1770. [More Information]
  • Stastny, F., Santamaría, A., Pérez-Severiano, F., Galván-Arzate, S., Ríos, C., Balcar, V. (2007). Quinolinic acids and peroxidative brain damage: relevance to schizophrenia (IN PRESS). In Abel Santamaria and Maria Esther Jimenez-Capdeville (Eds.), New Prospectives on Brain Cell Damage, Neurodegeneration and Neuroprotective Strategies, (pp. 113-134). Research Signpost.
  • Nasrallah, F., Griffin, J., Balcar, V., Rae, C. (2007). Understanding your inhibitions. Modulation of brain cortical metabolism by GABAB receptors. Journal of Cerebral Blood Flow and Metabolism, 27, 1510-1520. [More Information]

2006

  • Balcar, V., Nanitsos, E. (2006). Autoradiography of [3H]aspartate and glutamate transport in schizophrenia. Neuropsychopharmacology, 31, 685-686.
  • Stastny, F., Vrajová, M., Tejkalova, H., Peková, S., Mareš, V., Kozmiková, I., Jirásková, J., Höschl, C., Balcar, V. (2006). Composition and function of NMDA receptors in schizophrenia: from animal models to patients. Psychiatrie, 6(Supplement 2), 7-14.
  • El-Hajjmoussa, C., Rae, C., Bubb, W., Griffin, J., Deters, N., Balcar, V. (2006). Inhibitors of glutamate transport modulate distinct patterns in brain metabolism. Journal of Neuroscience Research, 85(2), 342-350. [More Information]
  • Bubenikova-Valesova, V., Balcar, V., Tejkalova, H., Langmeier, M., St’astny, F. (2006). Neonatal administration of N-acetyl-L-aspartyl-L-glutamate induces early neurodegeneration in hippocampus and alters behaviour in young adult rats. Neurochemistry International, 48(6-7), 515-522.
  • Kaiser, M., Mares, V., St’astny, F., Bubenikova-Valesova, V., Lisa, V., Suchomel, P., Balcar, V. (2006). The influence of interleukin-1 beta on gamma-glutamyl transpeptidase activity in rat hippocampus. Physiological Research, 55(4), 461-465.

2005

  • Rae, C., Moussa, C., Griffin, J., Parekh, S., Bubb, W., Hunt, N., Balcar, V. (2005). A metabolomic approach to ionotropic glutamate receptor subtype function: a nuclear magnetic resonance in vitro investigation. Journal of Cerebral Blood Flow and Metabolism, 26(8), 1005-1017. [More Information]
  • Platenik, J., Balcar, V., Yoneda, Y., Mioduszewska, B., Buchal, R., Hynek, R., Kilianek, L., Kuramoto, N., Wilczynski, G., Ogita, K., et al (2005). Apparent presence of Ser133-phosphorylated cyclic AMP response element binding protein (pCREB) in brain mitochondria is due to cross-reactivity of pCREB antibodies with pyruvate dehydrogenase. Journal of Neurochemistry, 95(5), 1446-1460. [More Information]
  • Kozmikova-Skuba, I., Klaschka, J., Tejkalova, H., Balcar, V., Stastny, F. (2005). Asymetrical hipocampal allocation of NR2 subunits of NMDA receptors in animal model of schizophrenia. Psychiatrie (Prague), Prague: Psychiatrie.
  • Balcar, V., Nanitsos, E. (2005). Glutamate transport - target for the next generation of neuroleptics? Psychiatrie, 9(Supplement 2), 19-23.
  • Nanitsos, E., Nguyen, K., St’astny, F., Balcar, V. (2005). Glutamatergic hypothesis of schizophrenia: involvement of Na(+)/K(+)-dependent glutamate transport. Journal of Biomedical Science, 12(6), 975-984. [More Information]
  • Rae, C., Moussa, C., Griffin, J., Bubb, W., Wallis, T., Balcar, V. (2005). Group I and II metabotropic glutamate receptors alter brain cortical metabolic and glutamate/glutamine cycle activity: a 13C NMR spectroscopy and metabolomic study. Journal of Neurochemistry, 92(2), 405-416. [More Information]
  • Kuramoto, N., Kubo, K., Ogita, K., Platenik, J., Balcar, V., Takarada, T., Nakamichi, N., Yoneda, Y. (2005). Nuclear Condensation of Cyclic Adenosine Monophosphate Responsive Element-Binding Protein in Discrete Murine Brain Structures. Journal of Neuroscience Research, 80(5), 667-676. [More Information]
  • Parekh, S., Moussa, C., Balcar, V., Hunt, N., Bubb, W., Rae, C. (2005). Quinolinic acid, kynurenic acid and dserine stimulate brain metabolism. 20th Biennial Meeting of the International Society for Neurochemistry/European Society for Neurochemistry, United Kingdom: Wiley-Blackwell Publishing Ltd.
  • Stastny, F., Tejkalova, H., Kozmikova-Skuba, I., Balcar, V., Kaiser, M., Yoneda, Y. (2005). Quinolinic acid, NMDA receptor and schizophrenia: Testing an integrative theory. In Yukio Yoneda (Eds.), Amino Acid Signalling 04, (pp. 67-83). India: Research Signpost.
  • Kaiser, M., Mareš, V., Sťastný, F., Bubenikova-Valesova, V., Lisá, V., Suchomel, P., Balcar, V. (2005). The influence of interleukin-1beta on gamma-glutamyl transpeptidase activity in rat hippocampus. Physiological Research, 55(4), 461-465. [More Information]

2004

  • Wallis, T., Rae, C., Balcar, V. (2004). Altered nAChR Subunit Expression In The Murine Model Of Duchenne Muscular Dystrophy. Journal of Neurochemistry, 88(1), 80-80.
  • Rae, C., McQuillan, J., Parekh, S., Bubb, W., Weiser, S., Balcar, V., Hansen, A., Ball, H., Hunt, N. (2004). Brain Gene Expression, Metabolism, And Bioenergetics: Interrelationships In Murine Models Of Cerebral And Noncerebral Malaria. The F A S E B Journal, 18(3), 499-510.
  • Nanitsos, E., Acosta, G., Saihara, Y., Stanton, D., Liao, L., Shin, J., Rae, C., Balcar, V. (2004). Effects Of Glutamate Transport Substrates And Glutamate Receptor Ligands On The Activity Of Na+/K+ -ATPase In Brain Tissue In Vitro. Clinical and Experimental Pharmacology and Physiology, 31(11), 762-769.
  • Wallis, T., Bubb, W., McQuillan, J., Balcar, V., Rae, C. (2004). For Want Of A Nail. Ramifications Of A Single Gene Deletion, Dystrophin, In The Brain Of The Mouse. Frontiers in Bioscience, 9(1), 74-84.
  • Nanitsos, E., Rae, C., Bubb, W., Balcar, V. (2004). Glutamate Uptake Is Significantly Increased In The Brain Of The PUFA-Deficient Rat. World Journal of Biological Psychiatry, 5(S1), 118-118.
  • Stastny, F., Tejkalova, H., Kozmikova-Skuba, I., Palenicek, T., Pliss, L., Mares, V., Kristofikova, Z., Kaiser, M., Bubenikova-Valesova, V., Balcar, V. (2004). Interactions Of Dopamine D1/D2 Receptor With Glutamate Receptor Of Nmda Type: From Molecules To Animal Models Of Schizophrenia (In Czech). Psychiatrie, 8(Suppl. 3), 32-41.
  • Takarada, T., Hinoi, E., Balcar, V., Taniura, H., Yoneda, Y. (2004). Possible Expression Of Functional Glutamate Transporters In The Rat Testis. Journal of Endocrinology, 181(2), 233-244.
  • St’astny, F., Lisy, V., Mares, V., Lisa, V., Balcar, V., Santamaria, A. (2004). Quinolinic Acid Induces Nmda Receptor-Mediated Lipid Peroxidation In Rat Brain Microvessels. Redox Report, 9(4), 229-233.

2003

  • Jeffrey, P., Balcar, V., Weinberger, R., Tolhurst, O., Meany, J. (2003). Avian purkinje neuronal cultures: extrinsic control of morphology by cell type and glutamate. In Hollenbeck, Bamburg (Eds.), Methods in Cell Biology: Volume 71: Neurons: Methods and applications for the Cell Biologist, (pp. 91-109). Amsterdam: Academic Press Elsevier. [More Information]
  • Stanton, D., Liao, L., Moussa, C., Bubb, W., Rae, C., Balcar, V. (2003). Can inhibition of glutamate transport contribute to the actions of neuroleptics? Psychiatrie, 7(1), 6-11.
  • Stasny, F., Lisy, V., V, M., Jezova, D., Santamaría, A., Balcar, V. (2003). Functional glutamate resceptors are expressed in rat brain capillary barrier. Psychiatrie, 7(2 suppl), 127-128.
  • Rae, C., Hare, N., Bubb, W., McEwan, S., Broer, A., McQuillan, J., Balcar, V., Conigrave, A., Broer, S. (2003). Inhibition of glutamine transport depletes glutamate and GABA neurotransmitter pools: further evidence for metabolic compartmentation. Journal of Neurochemistry, 85(2), 503-514.
  • Pliss, L., Balcar, V., Bubenikova, V., Pokorny, J., Fitzgibbon, T., Stasny, F. (2003). Morphology and ultrastructure of rat hippocampal formation after i.c.v administration of N-Acetyl-L-Aspartyl-L-Glutamate. Neuroscience, 122(1), 93-101.
  • Bubenikova, V., Balcar, V., Tejkalova, H., Horacek, J., Stastny, F. (2003). Significance of neonatal excitotoxic brain lesions in a neurodevelopmental model of schizophrenia. Psychiatrie, 7(S2), 19-20.
  • Takarada, T., Balcar, V., Baba, K., Takamoto, A., Acosta, G., Takano, K., Yoneda, Y. (2003). Uptake of [3H]L-serine in rat brain synaptosomal fractions. Brain Research, 983, 36-47.
  • St Asny, F., Tejkalova, H., Hoschel, C., Balcar, V. (2003). Viral infection, glutamatergic deficit and behavioural changes in animal model of schizophrenia. Psychiatrie, 7(suppl 2), 128-130.

2002

  • Hinoi, E., Fujimori, S., Kubo, K., Balcar, V., Ogita, K., Yoneda, Y. (2002). Constitutive expression of heterologous N-Methyl-D-aspartate receptor subunits in rat adrenal medulla. Journal of Neuroscience Research, 68(1), 36-45.
  • Takamoto, A., Quiggin, L., Lieb, I., Shave, E., Balcar, V., Yoneda, Y. (2002). Differences between D- and L-aspartate binding to the Na+-dependent binding sites on glutamate transporters in frozen sections of rat brain. Life Sciences, 70(9), 991-1001.
  • El-Hajjmoussa, C., Mitrovic, A., Vandenberg, R., Provis, T., Rae, C., Bubb, W., Balcar, V. (2002). Effects of L-Glutamate Transport Inhibition by a Conformationally Restricted Glutamate Analogue (2S,1’S,2’R)-2-(Carboxycyclopropyl)Glycine (L-CCG III)on Metabolism in Brain Tissue In Vitro Analysed by NMR Spectroscopy. Neurochemical Research, 27, 27-35.
  • Moussa, C., Mitrovic, A., Vandenberg, R., Provis, T., Rae, C., Bubb, W., Balcar, V. (2002). Effects of L-glutamate transport inhibition by a conformationally restricted glutamate analogue (2S,1"S,2'R)-2-(Carboxycyclopropyl) glycine (L-CCF III) on metabolism in brain tissue in vitro analysed by NMR spectroscopy. Neurochemical Research, 27(1), 27-35.
  • Balcar, V. (2002). Molecular pharmacology of the Na+-dependent transport of acidic amino acids in the mammalian central nervous system. Biological and Pharmaceutical Bulletin, 25(3), 291-301.
  • Pliss, L., Jezova, D., Mares, V., Balcar, V., Stastny, F. (2002). N-Acetyl-L-aspartyl-L-glutamate changes functional & structural properties of rat blood-brain barrier. Neuroscience Letters, 317(2), 85-88.
  • Hinoi, E., Balcar, V., Kuramoto, N., Nakamichi, N., Yoneda, Y. (2002). Nuclear transcription factors in the hippocampus. Progress in Neurobiology, 68(2), 145-165.
  • Hirai, T., Kuramoto, N., Maruyama, H., Balcar, V., Nakamura, Y., Yoneda, Y. (2002). Petentiation of Nuclear Activator Protein-1 DNA binding following brief exposure to N-Methly-D-Aspartate in immature cultured rat hippocampal neurons. Journal of Neuroscience Research, 67(4), 523-532.

2001

  • Pliss, L., Bubenikova, V., Balcar, V., Stastny, F. (2001). Characterization of hippocampal neurodegeneration after intracerebroventricular administration of N-acetyl-aspartyl-glutamate. Psychiatrie, 5 (suppl. 2), 102-104.
  • Stastny, F., Pliss, L., Skultétyová, I., Jezova, D., Bubenikova, V., Balcar, V. (2001). NAAG changes properties of blood brain barrier. Psychiatrie, 5 (suppl. 2), 134-136.
  • Balcar, V., Takamoto, A., Yonida,, Y. (2001). Neurochemistry of L-glutamiate transport in the CNS: A review of the thirty years of progress. Collection of Czechoslovak Chemical Communications, 9, 1315-1340.
  • Shave, E., Lawrence, M., Fitzgibbon, T., Balcar, V., Pliss, L., Stastny, F. (2001). Regional distribution and pharmacological characteristics of [3H]N-acetyle-aspartyl-glutamate (NAAG) binding sites in rat brain. Neurochemistry International, 38 (1), 53-62.
  • Balcar, V. (2001). Thirty years of L-glutamate transport in the CNS. Psychiatrie, 5 (suppl. 2), 2-4.

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