Dr Xiaosuo Wang

Bosch Mass Spectrometry Facility (BMSF) Officer
Bosch Institute: Sydney Medical School

Telephone +61 2 9036 3460
Fax +61 2 9036 3038

Website Bosch Mass Spectrometry Facility

Map

Current research students

Project title Research student
Evidence based use of supplements for hand osteoarthritis. Xiaoqian LIU

Selected grants

2016

  • Assessing protein level and distribution in Alzheimer’s disease-affected human brains using matrix assisted laser desorption / ionization (MALDI) imaging mass spectrometry: A methodology to image proteins in tissue without animal-derived antibodies; Witting P, Chami B, Sutherland G, Wang X, Youssef P; Medical Advances Without Animals/Research Grants.

2015

  • A role for neuroglobin in protecting neuronal cells in Alzheimer's disease; Witting P, Wang X; Rebecca L Cooper Medical Research Foundation/Equipment Grant.

Selected publications

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Book Chapters

  • Wang, X., Cai, X., Freedman, B., Witting, P. (2013). Role of SAA in Promoting Endothelial Activation: Inhibition by High-Density Lipoprotein. In Sabina Janciauskiene (Eds.), Acute Phase Proteins, (pp. 77-101). Rijeka, Croatia: InTech Publishers. [More Information]
  • Wang, X., Stocker, R. (2008). Detection of specifically oxidized apolipoproteins in oxidized HDL. In Donald Armstrong (Eds.), Methods in Molecular Biology 477:Advanced Protocols in Oxidative Stress I, (pp. 49-63). New York, USA: Humana Press. [More Information]

Journals

  • Guo, R., Blacker, D., Wang, X., Arima, H., Lavados, P., Lindley, R., Chalmers, J., Anderson, C., Robinson, T. (2017). Practice Patterns for Neurosurgical Utilization and Outcome in Acute Intracerebral Hemorrhage: Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trials 1 and 2 Studies. Neurosurgery, 81(6), 980-985. [More Information]
  • Brzozowska, N., de Tonnerre, E., Li, K., Wang, X., Boucher, A., Callaghan, P., Kuligowski, M., Wong, A., Arnold, J. (2017). The Differential Binding of Antipsychotic Drugs to the ABC Transporter P-Glycoprotein Predicts Cannabinoid-Antipsychotic Drug Interactions. Neuropsychopharmacology, 42(11), 2222-2231. [More Information]
  • Chami, B., Jeong, G., Varda, A., Maw, A., Kim, H., Fong, G., Simone, M., Rayner, B., Wang, X., Dennis, J., Witting, P. (2017). The nitroxide 4-methoxy TEMPO inhibits neutrophil-stimulated kinase activation in H9c2 cardiomyocytes. Archives of Biochemistry and Biophysics, 629, 19-35. [More Information]
  • Munoz Venturelli, P., Zahuranec, D., Wang, X., Lavados, P., Stapf, C., Lindley, R., Delcourt, C., Chalmers, J., Anderson, C., Robinson, T. (2017). Withdrawal of active treatment after intracerebral haemorrhage in the INTERACT2 study. Age and Ageing, 46(2), 329-332. [More Information]
  • Brzozowska, N., Li, K., Wang, X., Booth, J., Stuart, J., McGregor, I., Arnold, J. (2016). ABC transporters P-gp and Bcrp do not limit the brain uptake of the novel antipsychotic and anticonvulsant drug cannabidiol in mice. PeerJ, 4(5), 1-17. [More Information]
  • Qiu, M., Sato, S., Zheng, D., Wang, X., Carcel, C., Hirakawa, Y., Sandset, E., Delcourt, C., Arima, H., Wang, J., Chalmers, J., Anderson, C. (2016). Admission Heart Rate Predicts Poor Outcomes in Acute Intracerebral Hemorrhage: The Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial Studies. Stroke, 47(6), 1479-1485. [More Information]
  • Anderson, C., Robinson, T., Lindley, R., Arima, H., Lavados, P., Lee, T., Broderick, J., Chen, X., Chen, G., Sharma, V., Billot, L., Woodward, M., Li, Q., Wang, X., Chalmers, J., et al (2016). Low-dose versus standard-dose intravenous alteplase in acute ischemic stroke. New England Journal of Medicine, 374(24), 2313-2323. [More Information]
  • Wang, X., Kim, H., Szuchman-Sapir, A., McMahon, A., Dennis, J., Witting, P. (2016). Neutrophils recruited to the myocardium after acute experimental myocardial infarct generate hypochlorous acid that oxidizes cardiac myoglobin. Archives of Biochemistry and Biophysics, 612, 103-114. [More Information]
  • Parry-Jones, A., Wang, X., Sato, S., Mould, W., Vail, A., Anderson, C., Hanley, D. (2015). Edema Extension Distance: Outcome Measure for Phase II Clinical Trials Targeting Edema After Intracerebral Hemorrhage. Stroke, 46(6), e137-e140. [More Information]
  • Yang, J., Arima, H., Wu, G., Heeley, E., Delcourt, C., Zhou, J., Chen, G., Wang, X., Zhang, S., Yu, S., Chalmers, J., Anderson, C. (2015). Prognostic significance of perihematomal edema in acute intracerebral hemorrhage: pooled analysis from the intensive blood pressure reduction in acute cerebral hemorrhage trial studies. Stroke, 46(4), 1009-1013. [More Information]
  • Chami, B., Barrie, N., Cai, X., Wang, X., Paul, M., Morton-Chandra, R., Sharland, A., Dennis, J., Freedman, B., Witting, P. (2015). Serum amyloid a receptor blockade and incorporation into high-density lipoprotein modulates its pro-inflammatory and pro-thrombotic activities on vascular endothelial cells. International Journal of Molecular Sciences, 16(5), 11101-11124. [More Information]
  • Chan, E., Anderson, C., Wang, X., Arima, H., Saxena, A., Moullaali, T., Heeley, E., Delcourt, C., Wu, G., Wang, J., Chalmers, J., et al (2015). Significance of intraventricular hemorrhage in acute intracerebral hemorrhage: intensive blood pressure reduction in acute cerebral hemorrhage trial results. Stroke, 46(3), 653-658. [More Information]
  • Johnstone, D., El Massri, N., Moro, C., Spana, S., Wang, X., Torres, N., Chabrol, C., de Jaeger, X., Reinhart, F., Purushothuman, S., Stone, J., Mitrofanis, J., et al (2014). Indirect application of near infrared light induces neuroprotection in a mouse model of parkinsonism - an abscopal neuroprotective effect. Neuroscience, 274, 93-101. [More Information]
  • Cui, P., Rawling, T., Gillani, T., Bourget, K., Wang, X., Zhou, F., Murray, M. (2013). Anti-proliferative actions of N'-desmethylsorafenib in human breast cancer cells. Biochemical Pharmacology, 86(3), 419-427. [More Information]
  • Freewan, M., Rees, M., Sempertegui Plaza, T., Glaros, E., Lim, Y., Wang, X., Yeung, A., Witting, P., Terentis, A., Thomas, S. (2013). Human Indoleamine 2,3-Dioxygenase Is a Catalyst of Physiological Heme Peroxidase Reactions. Journal of Biological Chemistry, 288(3), 1548-1567. [More Information]
  • Groebler, L., Wang, X., Kim, H., Shanu, A., Hossain, F., McMahon, A., Witting, P. (2012). Cosupplementation with a synthetic, lipid-soluble polyphenol and vitamin C inhibits oxidative damage and improves vascular function yet does not inhibit acute renal injury in an animal model of rhabdomyolysis. Free Radical Biology and Medicine, 52(9), 1918-1928. [More Information]
  • Wang, X., Shao, B., Oda, M., Heinecke, J., Mahler, S., Stocker, R. (2009). A sensitive and specific ELISA detects methionine sulfoxide-containing apolipoprotein A-I in HDL. Journal of Lipid Research, 50(3), 586-594. [More Information]
  • Patel, S., Puranik, R., Nakhla, S., Lundmand, P., Stocker, R., Wang, X., Lambert, G., Rye, K., Barter, P., Nicholls, S., Celermajer, D. (2009). Acute hypertriglyceridaemia in humans increases the triglyceride content and decreases the anti-inflammatory capacity of high density lipoproteins. Atherosclerosis, 204(2), 424-428. [More Information]
  • Wang, X., Sun, J., Wang, C., France, M., Sheil, A. (2001). Effect of liver transplantation on islet allografts: up-regulation of Fas ligand and apoptosis of T lymphocytes are associated with islet graft tolerance. Transplantation, 72(1), 102-111.
  • Sun, J., Wang, X., Wang, C., France, M., Sheil, A. (2001). Increased Fas Ligand Expression and Activated T-Lymphocyte Apoptosis in Islet Graft Tolerance Induced by Liver Transplantation. Transplantation Proceedings, 33(1-2), 227-228. [More Information]

2017

  • Guo, R., Blacker, D., Wang, X., Arima, H., Lavados, P., Lindley, R., Chalmers, J., Anderson, C., Robinson, T. (2017). Practice Patterns for Neurosurgical Utilization and Outcome in Acute Intracerebral Hemorrhage: Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trials 1 and 2 Studies. Neurosurgery, 81(6), 980-985. [More Information]
  • Brzozowska, N., de Tonnerre, E., Li, K., Wang, X., Boucher, A., Callaghan, P., Kuligowski, M., Wong, A., Arnold, J. (2017). The Differential Binding of Antipsychotic Drugs to the ABC Transporter P-Glycoprotein Predicts Cannabinoid-Antipsychotic Drug Interactions. Neuropsychopharmacology, 42(11), 2222-2231. [More Information]
  • Chami, B., Jeong, G., Varda, A., Maw, A., Kim, H., Fong, G., Simone, M., Rayner, B., Wang, X., Dennis, J., Witting, P. (2017). The nitroxide 4-methoxy TEMPO inhibits neutrophil-stimulated kinase activation in H9c2 cardiomyocytes. Archives of Biochemistry and Biophysics, 629, 19-35. [More Information]
  • Munoz Venturelli, P., Zahuranec, D., Wang, X., Lavados, P., Stapf, C., Lindley, R., Delcourt, C., Chalmers, J., Anderson, C., Robinson, T. (2017). Withdrawal of active treatment after intracerebral haemorrhage in the INTERACT2 study. Age and Ageing, 46(2), 329-332. [More Information]

2016

  • Brzozowska, N., Li, K., Wang, X., Booth, J., Stuart, J., McGregor, I., Arnold, J. (2016). ABC transporters P-gp and Bcrp do not limit the brain uptake of the novel antipsychotic and anticonvulsant drug cannabidiol in mice. PeerJ, 4(5), 1-17. [More Information]
  • Qiu, M., Sato, S., Zheng, D., Wang, X., Carcel, C., Hirakawa, Y., Sandset, E., Delcourt, C., Arima, H., Wang, J., Chalmers, J., Anderson, C. (2016). Admission Heart Rate Predicts Poor Outcomes in Acute Intracerebral Hemorrhage: The Intensive Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial Studies. Stroke, 47(6), 1479-1485. [More Information]
  • Anderson, C., Robinson, T., Lindley, R., Arima, H., Lavados, P., Lee, T., Broderick, J., Chen, X., Chen, G., Sharma, V., Billot, L., Woodward, M., Li, Q., Wang, X., Chalmers, J., et al (2016). Low-dose versus standard-dose intravenous alteplase in acute ischemic stroke. New England Journal of Medicine, 374(24), 2313-2323. [More Information]
  • Wang, X., Kim, H., Szuchman-Sapir, A., McMahon, A., Dennis, J., Witting, P. (2016). Neutrophils recruited to the myocardium after acute experimental myocardial infarct generate hypochlorous acid that oxidizes cardiac myoglobin. Archives of Biochemistry and Biophysics, 612, 103-114. [More Information]

2015

  • Parry-Jones, A., Wang, X., Sato, S., Mould, W., Vail, A., Anderson, C., Hanley, D. (2015). Edema Extension Distance: Outcome Measure for Phase II Clinical Trials Targeting Edema After Intracerebral Hemorrhage. Stroke, 46(6), e137-e140. [More Information]
  • Yang, J., Arima, H., Wu, G., Heeley, E., Delcourt, C., Zhou, J., Chen, G., Wang, X., Zhang, S., Yu, S., Chalmers, J., Anderson, C. (2015). Prognostic significance of perihematomal edema in acute intracerebral hemorrhage: pooled analysis from the intensive blood pressure reduction in acute cerebral hemorrhage trial studies. Stroke, 46(4), 1009-1013. [More Information]
  • Chami, B., Barrie, N., Cai, X., Wang, X., Paul, M., Morton-Chandra, R., Sharland, A., Dennis, J., Freedman, B., Witting, P. (2015). Serum amyloid a receptor blockade and incorporation into high-density lipoprotein modulates its pro-inflammatory and pro-thrombotic activities on vascular endothelial cells. International Journal of Molecular Sciences, 16(5), 11101-11124. [More Information]
  • Chan, E., Anderson, C., Wang, X., Arima, H., Saxena, A., Moullaali, T., Heeley, E., Delcourt, C., Wu, G., Wang, J., Chalmers, J., et al (2015). Significance of intraventricular hemorrhage in acute intracerebral hemorrhage: intensive blood pressure reduction in acute cerebral hemorrhage trial results. Stroke, 46(3), 653-658. [More Information]

2014

  • Johnstone, D., El Massri, N., Moro, C., Spana, S., Wang, X., Torres, N., Chabrol, C., de Jaeger, X., Reinhart, F., Purushothuman, S., Stone, J., Mitrofanis, J., et al (2014). Indirect application of near infrared light induces neuroprotection in a mouse model of parkinsonism - an abscopal neuroprotective effect. Neuroscience, 274, 93-101. [More Information]

2013

  • Cui, P., Rawling, T., Gillani, T., Bourget, K., Wang, X., Zhou, F., Murray, M. (2013). Anti-proliferative actions of N'-desmethylsorafenib in human breast cancer cells. Biochemical Pharmacology, 86(3), 419-427. [More Information]
  • Freewan, M., Rees, M., Sempertegui Plaza, T., Glaros, E., Lim, Y., Wang, X., Yeung, A., Witting, P., Terentis, A., Thomas, S. (2013). Human Indoleamine 2,3-Dioxygenase Is a Catalyst of Physiological Heme Peroxidase Reactions. Journal of Biological Chemistry, 288(3), 1548-1567. [More Information]
  • Wang, X., Cai, X., Freedman, B., Witting, P. (2013). Role of SAA in Promoting Endothelial Activation: Inhibition by High-Density Lipoprotein. In Sabina Janciauskiene (Eds.), Acute Phase Proteins, (pp. 77-101). Rijeka, Croatia: InTech Publishers. [More Information]

2012

  • Groebler, L., Wang, X., Kim, H., Shanu, A., Hossain, F., McMahon, A., Witting, P. (2012). Cosupplementation with a synthetic, lipid-soluble polyphenol and vitamin C inhibits oxidative damage and improves vascular function yet does not inhibit acute renal injury in an animal model of rhabdomyolysis. Free Radical Biology and Medicine, 52(9), 1918-1928. [More Information]

2009

  • Wang, X., Shao, B., Oda, M., Heinecke, J., Mahler, S., Stocker, R. (2009). A sensitive and specific ELISA detects methionine sulfoxide-containing apolipoprotein A-I in HDL. Journal of Lipid Research, 50(3), 586-594. [More Information]
  • Patel, S., Puranik, R., Nakhla, S., Lundmand, P., Stocker, R., Wang, X., Lambert, G., Rye, K., Barter, P., Nicholls, S., Celermajer, D. (2009). Acute hypertriglyceridaemia in humans increases the triglyceride content and decreases the anti-inflammatory capacity of high density lipoproteins. Atherosclerosis, 204(2), 424-428. [More Information]

2008

  • Wang, X., Stocker, R. (2008). Detection of specifically oxidized apolipoproteins in oxidized HDL. In Donald Armstrong (Eds.), Methods in Molecular Biology 477:Advanced Protocols in Oxidative Stress I, (pp. 49-63). New York, USA: Humana Press. [More Information]

2001

  • Wang, X., Sun, J., Wang, C., France, M., Sheil, A. (2001). Effect of liver transplantation on islet allografts: up-regulation of Fas ligand and apoptosis of T lymphocytes are associated with islet graft tolerance. Transplantation, 72(1), 102-111.
  • Sun, J., Wang, X., Wang, C., France, M., Sheil, A. (2001). Increased Fas Ligand Expression and Activated T-Lymphocyte Apoptosis in Islet Graft Tolerance Induced by Liver Transplantation. Transplantation Proceedings, 33(1-2), 227-228. [More Information]

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