Dr Ya Wang

Research Fellow
The Westmead Institute for Medical Research

Telephone +61 2 8627 3510

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Selected grants

2017

  • Mitochondrial transplantation; Wang Y; Sydney Medical School Foundation/NMRF Seed Funding Grant.

Selected publications

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Journals

  • Shah, R., Li, Q., Zhao, W., Tedja, M., Tideman, J., Khawaja, A., Fan, Q., Yazar, S., Williams, K., Verhoeven, V., Wang, Y., Mitchell, P., et al (2018). A genome-wide association study of corneal astigmatism: The CREAM Consortium. Molecular Vision, 24, 127-142.
  • Zhou, J., Wang, Y., Lee, V., Zhang, G., Medbury, H., Williams, H., Wang, Y., Tan, T., Harris, D., Alexander, S., Durkan, A. (2018). DEC205-DC targeted DNA vaccine against CX3CR1 protects against atherogenesis in mice. PloS One, 13(4), e0195657. [More Information]
  • Huang, D., Wang, Y., Hawthorne, W., Hu, M., Hawkes, J., Burns, H., Davies, S., Gao, F., Chew, Y., Yi, S., O'Connell, P. (2017). Ex vivo-expanded baboon CD39�+� regulatory T cells prevent rejection of porcine islet xenografts in NOD-SCID IL-2ry(-/-) mice reconstituted with baboon peripheral blood mononuclear cells. Xenotransplantation, 24(6), 1-11. [More Information]
  • Wang, Y., Zhang, G., Wang, Y., Hu, M., Zhou, J., Sawyer, A., Cao, Q., Wang, Y., Zheng, G., Lee, V., Harris, D., Alexander, S. (2017). Exacerbation of spontaneous autoimmune nephritis following regulatory T cell depletion in B cell lymphoma 2-interacting mediator knock-out mice. Clinical and Experimental Immunology, 188(2), 195-207. [More Information]
  • Zheng, G., Zhang, J., Zhao, H., Wang, H., Pang, M., Qiao, X., Lee, S., Hsu, T., Tan, T., Lyons, G., Zhao, Y., Loebel, D., Wang, Y., Wang, Y., Wang, Y., Cao, Q., Wang, C., Lee, V., Tam, P., Harris, D., et al (2016). a3 Integrin of Cell-Cell Contact Mediates Kidney Fibrosis by Integrin-Linked Kinase in Proximal Tubular E-Cadherin Deficient Mice. American Journal of Pathology, 186(7), 1847-1860. [More Information]
  • Wang, Y., Ghali, J., Zhang, G., Hu, M., Wang, Y., Sawyer, A., Zhou, J., Hapudeniya, D., Wang, Y., Cao, Q., Zheng, G., Harris, D., Alexander, S. (2016). Development and function of Foxp3+ regulatory T cells. Nephrology, 21(2), 81-85. [More Information]
  • Zhao, Y., Qiao, X., Wang, L., Tan, T., Zhao, H., Zhang, Y., Zhang, J., Rao, P., Cao, Q., Wang, Y., Wang, Y., Wang, Y., Lee, V., Harris, D., Zheng, G., et al (2016). Matrix metalloproteinase 9 induces endothelial-mesenchymal transition via Notch activation in human kidney glomerular endothelial cells. BMC Cell Biology, 17(1), 1-11. [More Information]
  • Sun, Y., Wang, Y., Cao, Q., Yu, H., Zheng, D., Wang, Y., Harris, D. (2015). Expression and Role of CD166 in the Chronic Kidney Disease. Iranian Journal of Pediatrics, 25(5), 1-8. [More Information]
  • Cao, Q., Wang, Y., Zheng, D., Sun, Y., Wang, C., Wang, X., Lee, V., Wang, Y., Wang, Y., Zheng, G., Tan, T., Harris, D., et al (2014). Failed renoprotection by alternatively activated macrophages from bone marrow due to proliferation-dependent phenotype switch in vivo. Kidney International, 85(4), 794-806. [More Information]
  • Zhao, Y., Zhao, H., Zhang, Y., Tsatralis, T., Cao, Q., Wang, Y., Wang, Y., Wang, Y., Alexander, S., Harris, D., Zheng, G. (2014). Isolation and epithelial co-culture of mouse renal peritubular endothelial cells. BMC Cell Biology, 15(1), 1-10. [More Information]
  • Wang, Y., Wang, Y., Wang, Y., Zheng, G., Tan, T., Lee, S., Zhang, J., Zhang, G., Hu, M., Wang, C., Cao, Q., Zhao, Y., Harris, D., et al (2014). Regulatory T cells require renal antigen recognition through the TCR to protect against injury in nephritis. International Journal of Clinical and Experimental Pathology, 7(1), 38-47.
  • Tian, X., Zhang, J., Tan, T., Lyons, G., Zhao, H., Niu, B., Lee, S., Tsatralis, T., Zhao, Y., Wang, Y., Cao, Q., Wang, C., Wang, Y., Lee, V., Zheng, G., Harris, D., et al (2013). Association of beta catenin with P-Smad3 but not LEF-1 dissociates in vitro profibrotic from anti-inflammatory effects of TGF- beta1. Journal of Cell Science, 126(1), 67-76. [More Information]
  • Wang, Y., Zhou, J., Wang, Y., Watson, D., Zhang, G., Hu, M., Wu, H., Zheng, G., Wang, Y., Durkan, A., Harris, D., Alexander, S. (2013). Daedalic DNA vaccination against self antigens as a treatment for chronic kidney disease. International Journal of Clinical and Experimental Pathology, 6(3), 326-333. [More Information]
  • Lu, J., Cao, Q., Zheng, D., Sun, Y., Wang, C., Yu, X., Wang, Y., Lee, V., Zheng, G., Tan, T., Wang, X., Harris, D., Wang, Y., et al (2013). Discrete functions of M2a and M2c macrophage subsets determine their relative efficacy in treating chronic kidney disease. Kidney International, 84(4), 745-755. [More Information]
  • Wang, Y., Wang, Y., Wang, Y., Zheng, G., Zhang, G., Zhou, J., Tan, T., Cao, Q., Hu, M., Watson, D., Wu, H., Zheng, D., Wang, C., Harris, D., et al (2013). DNA vaccine encoding CD40 targeted to dendritic cells in situ prevents the development of Heymann nephritis in rats. Kidney International, 83(2), 223-232. [More Information]
  • Tan, T., Zheng, G., Hsu, T., Lee, S., Zhang, J., Zhao, Y., Tian, X., Wang, Y., Wang, Y., Cao, Q., Wang, Y., Lee, V., Wang, C., Zheng, D., Alexander, S., Harris, D., et al (2013). Matrix metalloproteinase-9 of tubular and macrophage origin contributes to the pathogenesis of renal fibrosis via macrophage recruitment through osteopontin cleavage. Laboratory Investigation, 93(4), 434-449. [More Information]
  • Wang, Y., Zhang, G., Hu, M., Polhill, T., Sawyer, A., Zhou, J., Saito, M., Watson, D., Wu, H., Wang, Y., Wang, X., Wang, Y., Harris, D., Alexander, S. (2012). CD8+ Regulatory T Cells Induced by T Cell Vaccination Protect Against Autoimmune Nephritis. Journal of the American Society of Nephrology, 23(6), 1058-1067. [More Information]
  • Zhou, J., Wang, Y., Lee, V., Phoon, R., Zhang, G., Wang, Y., Tan, T., Hu, M., Wang, D., Saito, M., Harris, D., Durkan, A., et al (2012). DEC205-DC targeted DNA vaccines to CX3CR1 and CCL2 are potent and limit macrophage migration. International Journal of Clinical and Experimental Medicine, 5(1), 24-33. [More Information]
  • Polhill, T., Zhang, G., Hu, M., Sawyer, A., Zhou, J., Saito, M., Webster, K., Wang, Y., Wang, Y., Grey, S., Harris, D., Alexander, S., Wang, Y., et al (2012). IL-2/IL-2Ab Complexes Induce Regulatory T Cell Expansion and Protect against Proteinuric CKD. Journal of the American Society of Nephrology, 23(8), 1303-1308. [More Information]
  • Zheng, D., Cao, Q., Lee, V., Wang, Y., Zheng, G., Wang, Y., Tan, T., Wang, C., Alexander, S., Harris, D., Wang, Y. (2012). Lipopolysaccharide-pretreated plasmacytoid dendritic cells ameliorate experimental chronic kidney disease. Kidney International, 81(9), 892-902. [More Information]
  • Wang, Y., McRae, J., Robson, S., Cowan, P., Zhang, G., Hu, M., Polhill, T., Wang, Y., Zheng, G., Wang, Y., Lee, V., Harris, D., Alexander, S., et al (2012). Regulatory T cells participate in CD39-mediated protection from renal injury. European Journal of Immunology, 42(9), 2441-2451. [More Information]
  • Cao, Q., Wang, C., Zheng, D., Wang, Y., Lee, V., Wang, Y., Zheng, G., Tan, T., Yu, D., Alexander, S., Harris, D., Wang, Y. (2011). IL-25 Induces M2 Macrophages and Reduces Renal Injury in Proteinuric Kidney Disease. Journal of the American Society of Nephrology, 22(7), 1229-1239. [More Information]
  • Sun, Y., Yu, H., Zheng, D., Cao, Q., Wang, Y., Harris, D., Wang, Y. (2011). Sudan Black B Reduces Autofluorescence in Murine Renal Tissue. Archives of Pathology & Laboratory Medicine, 135(10), 1335-1342. [More Information]
  • Zheng, D., Wang, Y., Cao, Q., Lee, V., Zheng, G., Sun, Y., Tan, T., Wang, Y., Alexander, S., Harris, D. (2011). Transfused Macrophages Ameliorate Pancreatic and Renal Injury in Murine Diabetes Mellitus. Nephron Experimental Nephrology, 118(4), e87-e99. [More Information]
  • Cao, Q., Wang, Y., Zheng, D., Sun, Y., Wang, Y., Lee, V., Zheng, G., Tan, T., Ince, J., Alexander, S., Harris, D. (2010). IL-10/TGF-{beta}-Modified Macrophages Induce Regulatory T Cells and Protect against Adriamycin Nephrosis. Journal of the American Society of Nephrology, 21(6), 933-942. [More Information]
  • Tan, T., Zheng, G., Hsu, T., Wang, Y., Lee, V., Tian, X., Wang, Y., Cao, Q., Wang, Y., Harris, D. (2010). Macrophage Matrix Metalloproteinase-9 Mediates Epithelial-Mesenchymal Transition in Vitro in Murine Renal Tubular Cells. American Journal of Pathology, 176(3), 1256-1270. [More Information]
  • Lee, V., Qin, X., Wang, Y., Zheng, G., Wang, Y., Wang, Y., Ince, J., Tan, T., Kairaitis, L., Alexander, S., Harris, D. (2010). The CD40-CD154 co-stimulation pathway mediates innate immune injury in adriamycin nephrosis. Nephrology, Dialysis, Transplantation, 25(3), 717-730. [More Information]
  • Wang, Y., Hu, M., Wang, Y., Polhill, T., Zhang, G., Wang, Y., Lee, V., Harris, D., Alexander, S. (2008). Regulatory T Cells in Renal Disease. International Journal of Clinical and Experimental Medicine, 1(4), 294-304. [More Information]

2018

  • Shah, R., Li, Q., Zhao, W., Tedja, M., Tideman, J., Khawaja, A., Fan, Q., Yazar, S., Williams, K., Verhoeven, V., Wang, Y., Mitchell, P., et al (2018). A genome-wide association study of corneal astigmatism: The CREAM Consortium. Molecular Vision, 24, 127-142.
  • Zhou, J., Wang, Y., Lee, V., Zhang, G., Medbury, H., Williams, H., Wang, Y., Tan, T., Harris, D., Alexander, S., Durkan, A. (2018). DEC205-DC targeted DNA vaccine against CX3CR1 protects against atherogenesis in mice. PloS One, 13(4), e0195657. [More Information]

2017

  • Huang, D., Wang, Y., Hawthorne, W., Hu, M., Hawkes, J., Burns, H., Davies, S., Gao, F., Chew, Y., Yi, S., O'Connell, P. (2017). Ex vivo-expanded baboon CD39�+� regulatory T cells prevent rejection of porcine islet xenografts in NOD-SCID IL-2ry(-/-) mice reconstituted with baboon peripheral blood mononuclear cells. Xenotransplantation, 24(6), 1-11. [More Information]
  • Wang, Y., Zhang, G., Wang, Y., Hu, M., Zhou, J., Sawyer, A., Cao, Q., Wang, Y., Zheng, G., Lee, V., Harris, D., Alexander, S. (2017). Exacerbation of spontaneous autoimmune nephritis following regulatory T cell depletion in B cell lymphoma 2-interacting mediator knock-out mice. Clinical and Experimental Immunology, 188(2), 195-207. [More Information]

2016

  • Zheng, G., Zhang, J., Zhao, H., Wang, H., Pang, M., Qiao, X., Lee, S., Hsu, T., Tan, T., Lyons, G., Zhao, Y., Loebel, D., Wang, Y., Wang, Y., Wang, Y., Cao, Q., Wang, C., Lee, V., Tam, P., Harris, D., et al (2016). a3 Integrin of Cell-Cell Contact Mediates Kidney Fibrosis by Integrin-Linked Kinase in Proximal Tubular E-Cadherin Deficient Mice. American Journal of Pathology, 186(7), 1847-1860. [More Information]
  • Wang, Y., Ghali, J., Zhang, G., Hu, M., Wang, Y., Sawyer, A., Zhou, J., Hapudeniya, D., Wang, Y., Cao, Q., Zheng, G., Harris, D., Alexander, S. (2016). Development and function of Foxp3+ regulatory T cells. Nephrology, 21(2), 81-85. [More Information]
  • Zhao, Y., Qiao, X., Wang, L., Tan, T., Zhao, H., Zhang, Y., Zhang, J., Rao, P., Cao, Q., Wang, Y., Wang, Y., Wang, Y., Lee, V., Harris, D., Zheng, G., et al (2016). Matrix metalloproteinase 9 induces endothelial-mesenchymal transition via Notch activation in human kidney glomerular endothelial cells. BMC Cell Biology, 17(1), 1-11. [More Information]

2015

  • Sun, Y., Wang, Y., Cao, Q., Yu, H., Zheng, D., Wang, Y., Harris, D. (2015). Expression and Role of CD166 in the Chronic Kidney Disease. Iranian Journal of Pediatrics, 25(5), 1-8. [More Information]

2014

  • Cao, Q., Wang, Y., Zheng, D., Sun, Y., Wang, C., Wang, X., Lee, V., Wang, Y., Wang, Y., Zheng, G., Tan, T., Harris, D., et al (2014). Failed renoprotection by alternatively activated macrophages from bone marrow due to proliferation-dependent phenotype switch in vivo. Kidney International, 85(4), 794-806. [More Information]
  • Zhao, Y., Zhao, H., Zhang, Y., Tsatralis, T., Cao, Q., Wang, Y., Wang, Y., Wang, Y., Alexander, S., Harris, D., Zheng, G. (2014). Isolation and epithelial co-culture of mouse renal peritubular endothelial cells. BMC Cell Biology, 15(1), 1-10. [More Information]
  • Wang, Y., Wang, Y., Wang, Y., Zheng, G., Tan, T., Lee, S., Zhang, J., Zhang, G., Hu, M., Wang, C., Cao, Q., Zhao, Y., Harris, D., et al (2014). Regulatory T cells require renal antigen recognition through the TCR to protect against injury in nephritis. International Journal of Clinical and Experimental Pathology, 7(1), 38-47.

2013

  • Tian, X., Zhang, J., Tan, T., Lyons, G., Zhao, H., Niu, B., Lee, S., Tsatralis, T., Zhao, Y., Wang, Y., Cao, Q., Wang, C., Wang, Y., Lee, V., Zheng, G., Harris, D., et al (2013). Association of beta catenin with P-Smad3 but not LEF-1 dissociates in vitro profibrotic from anti-inflammatory effects of TGF- beta1. Journal of Cell Science, 126(1), 67-76. [More Information]
  • Wang, Y., Zhou, J., Wang, Y., Watson, D., Zhang, G., Hu, M., Wu, H., Zheng, G., Wang, Y., Durkan, A., Harris, D., Alexander, S. (2013). Daedalic DNA vaccination against self antigens as a treatment for chronic kidney disease. International Journal of Clinical and Experimental Pathology, 6(3), 326-333. [More Information]
  • Lu, J., Cao, Q., Zheng, D., Sun, Y., Wang, C., Yu, X., Wang, Y., Lee, V., Zheng, G., Tan, T., Wang, X., Harris, D., Wang, Y., et al (2013). Discrete functions of M2a and M2c macrophage subsets determine their relative efficacy in treating chronic kidney disease. Kidney International, 84(4), 745-755. [More Information]
  • Wang, Y., Wang, Y., Wang, Y., Zheng, G., Zhang, G., Zhou, J., Tan, T., Cao, Q., Hu, M., Watson, D., Wu, H., Zheng, D., Wang, C., Harris, D., et al (2013). DNA vaccine encoding CD40 targeted to dendritic cells in situ prevents the development of Heymann nephritis in rats. Kidney International, 83(2), 223-232. [More Information]
  • Tan, T., Zheng, G., Hsu, T., Lee, S., Zhang, J., Zhao, Y., Tian, X., Wang, Y., Wang, Y., Cao, Q., Wang, Y., Lee, V., Wang, C., Zheng, D., Alexander, S., Harris, D., et al (2013). Matrix metalloproteinase-9 of tubular and macrophage origin contributes to the pathogenesis of renal fibrosis via macrophage recruitment through osteopontin cleavage. Laboratory Investigation, 93(4), 434-449. [More Information]

2012

  • Wang, Y., Zhang, G., Hu, M., Polhill, T., Sawyer, A., Zhou, J., Saito, M., Watson, D., Wu, H., Wang, Y., Wang, X., Wang, Y., Harris, D., Alexander, S. (2012). CD8+ Regulatory T Cells Induced by T Cell Vaccination Protect Against Autoimmune Nephritis. Journal of the American Society of Nephrology, 23(6), 1058-1067. [More Information]
  • Zhou, J., Wang, Y., Lee, V., Phoon, R., Zhang, G., Wang, Y., Tan, T., Hu, M., Wang, D., Saito, M., Harris, D., Durkan, A., et al (2012). DEC205-DC targeted DNA vaccines to CX3CR1 and CCL2 are potent and limit macrophage migration. International Journal of Clinical and Experimental Medicine, 5(1), 24-33. [More Information]
  • Polhill, T., Zhang, G., Hu, M., Sawyer, A., Zhou, J., Saito, M., Webster, K., Wang, Y., Wang, Y., Grey, S., Harris, D., Alexander, S., Wang, Y., et al (2012). IL-2/IL-2Ab Complexes Induce Regulatory T Cell Expansion and Protect against Proteinuric CKD. Journal of the American Society of Nephrology, 23(8), 1303-1308. [More Information]
  • Zheng, D., Cao, Q., Lee, V., Wang, Y., Zheng, G., Wang, Y., Tan, T., Wang, C., Alexander, S., Harris, D., Wang, Y. (2012). Lipopolysaccharide-pretreated plasmacytoid dendritic cells ameliorate experimental chronic kidney disease. Kidney International, 81(9), 892-902. [More Information]
  • Wang, Y., McRae, J., Robson, S., Cowan, P., Zhang, G., Hu, M., Polhill, T., Wang, Y., Zheng, G., Wang, Y., Lee, V., Harris, D., Alexander, S., et al (2012). Regulatory T cells participate in CD39-mediated protection from renal injury. European Journal of Immunology, 42(9), 2441-2451. [More Information]

2011

  • Cao, Q., Wang, C., Zheng, D., Wang, Y., Lee, V., Wang, Y., Zheng, G., Tan, T., Yu, D., Alexander, S., Harris, D., Wang, Y. (2011). IL-25 Induces M2 Macrophages and Reduces Renal Injury in Proteinuric Kidney Disease. Journal of the American Society of Nephrology, 22(7), 1229-1239. [More Information]
  • Sun, Y., Yu, H., Zheng, D., Cao, Q., Wang, Y., Harris, D., Wang, Y. (2011). Sudan Black B Reduces Autofluorescence in Murine Renal Tissue. Archives of Pathology & Laboratory Medicine, 135(10), 1335-1342. [More Information]
  • Zheng, D., Wang, Y., Cao, Q., Lee, V., Zheng, G., Sun, Y., Tan, T., Wang, Y., Alexander, S., Harris, D. (2011). Transfused Macrophages Ameliorate Pancreatic and Renal Injury in Murine Diabetes Mellitus. Nephron Experimental Nephrology, 118(4), e87-e99. [More Information]

2010

  • Cao, Q., Wang, Y., Zheng, D., Sun, Y., Wang, Y., Lee, V., Zheng, G., Tan, T., Ince, J., Alexander, S., Harris, D. (2010). IL-10/TGF-{beta}-Modified Macrophages Induce Regulatory T Cells and Protect against Adriamycin Nephrosis. Journal of the American Society of Nephrology, 21(6), 933-942. [More Information]
  • Tan, T., Zheng, G., Hsu, T., Wang, Y., Lee, V., Tian, X., Wang, Y., Cao, Q., Wang, Y., Harris, D. (2010). Macrophage Matrix Metalloproteinase-9 Mediates Epithelial-Mesenchymal Transition in Vitro in Murine Renal Tubular Cells. American Journal of Pathology, 176(3), 1256-1270. [More Information]
  • Lee, V., Qin, X., Wang, Y., Zheng, G., Wang, Y., Wang, Y., Ince, J., Tan, T., Kairaitis, L., Alexander, S., Harris, D. (2010). The CD40-CD154 co-stimulation pathway mediates innate immune injury in adriamycin nephrosis. Nephrology, Dialysis, Transplantation, 25(3), 717-730. [More Information]

2008

  • Wang, Y., Hu, M., Wang, Y., Polhill, T., Zhang, G., Wang, Y., Lee, V., Harris, D., Alexander, S. (2008). Regulatory T Cells in Renal Disease. International Journal of Clinical and Experimental Medicine, 1(4), 294-304. [More Information]

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