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Dr Yan Li

Experimental Embryologist
Medicine, Northern Clinical School

Telephone +61 2 99264871
Fax +61 2 9926 6343

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Current research students

Project title Research student
Molecular regulation of embryo development Albaraa MOJADADI
Genotoxic damage in the early embryo Wed SALAH
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Selected grants

2011

  • Epigenetic reprograming after fertilization; O'Neill C, Li Y; National Health and Medical Research Council (NHMRC)/Project Grants.
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Selected publications

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Book Chapters

  • O'Neill, C., Li, Y., Jin, X. (2015). Survival Signalling in the Preimplantation Embryo. In Henry J. Leese, Daniel R. Brison (Eds.), Cell Signaling During Mammalian Early Embryo Development, (pp. 129-149). New York: Springer Science+Business Media. [More Information]

Journals

  • Rollo, C., Li, Y., Jin, X., O'Neill, C. (2017). Histone 3 lysine 9 acetylation is a biomarker of the effects of culture on zygotes. Reproduction, 154(4), 375-385. [More Information]
  • Li, Y., O'Neill, C. (2017). Immunological Staining of Global Changes in DNA Methylation in the Early Mammalian Embryo. Methods in Molecular Biology, 1605, 161-169. [More Information]
  • Celik-Uzuner, S., Li, Y., Peters, L., O'Neill, C. (2017). Measurement of global DNA methylation levels by flow cytometry in mouse fibroblasts. In Vitro Cellular & Developmental Biology. Animal, 53(1), 1-6. [More Information]
  • Li, Y., Seah, M., O'Neill, C. (2016). Mapping global changes in nuclear cytosine base modifications in the early mouse embryo. Reproduction, 151(2), 83-95. [More Information]
  • Salvaing, J., Li, Y., Beaujean, N., O'Neill, C. (2015). Determinants of valid measurements of global changes in 5'-methylcytosine and 5'-hydroxymethylcytosine by immunolocalisation in the early embryo. Reproduction, Fertility and Development, 27(5), 755-764. [More Information]
  • Celik, S., Li, Y., O'Neill, C. (2015). The effect of DNA damage on the pattern of immune-detectable DNA methylation in mouse embryonic fibroblasts. Experimental Cell Research, 339(1), 20-34. [More Information]
  • Wong, J., Jack, M., Li, Y., O'Neill, C. (2014). The Epigenetic Bivalency of Core Pancreatic b-Cell Transcription Factor Genes within Mouse Pluripotent Embryonic Stem Cells Is Not Affected by Knockdown of the Polycomb Repressive Complex 2, SUZ12. PloS One, 9(5), 1-12. [More Information]
  • Celik, S., Li, Y., O'Neill, C. (2014). The Exit of Mouse Embryonic Fibroblasts from the Cell-Cycle Changes the Nature of Solvent Exposure of the 5'-Methylcytosine Epitope within Chromatin. PloS One, 9(4), 1-12. [More Information]
  • Li, Y., O'Neill, C. (2013). 5'-methylcytosine and 5'-hydroxymethylcytosine Each Provide Epigenetic Information to the Mouse Zygote. PloS One, 8(5), 1-9. [More Information]
  • Li, Y., O'Neill, C. (2012). Persistence of Cytosine Methylation of DNA following Fertilisation in the Mouse. PloS One, 7(1), 1-11. [More Information]
  • O'Neill, C., Li, Y., Jin, X. (2012). Survival signaling in the preimplantation embryo. Theriogenology, 77(4), 773-784. [More Information]
  • Mu, X., Jin, X., Farnham, M., Li, Y., O'Neill, C. (2011). DNA Damage-Sensing Kinases Mediate the Mouse 2-Cell Embryo's Response to Genotoxic Stress. Biology Of Reproduction, 85(3), 524-535. [More Information]
  • Beardsley, A., Li, Y., O'Neill, C. (2010). Characterization of a diverse secretome generated by the mouse preimplantation embryo in vitro. Reproductive Biology and Endocrinology, 8(71), 1-10. [More Information]
  • Li, Y., O'Neill, C., Day, M. (2009). Activation of a Chloride Channel by a Trophic Ligand Is Required for Development of the Mouse Preimplantation Embryo In Vitro. Biology Of Reproduction, 81(4), 759-767. [More Information]
  • Li, Y., Day, M., O'Neill, C. (2007). Autocrine activation of ion currents in the two-cell mouse embryo. Experimental Cell Research, 313(13), 2786-2794. [More Information]
  • Li, Y., Chandrakanthan, V., Day, M., O'Neill, C. (2007). Direct evidence for the action of phosphatidylinositol (3,4,5)-trisphosphate-mediated signal transduction in the 2-cell mouse embryo. Biology Of Reproduction, 77(5), 813-821. [More Information]
  • Gottlieb, D., Micklethwaite, K., Bradstock, K., Li, Y. (2007). Rapid expansion of tumor-reactive cells from HLA-matched siblings for adoptive immunotherapy of melanoma. Cytotherapy, 9(2), 133-143. [More Information]
  • Lu, D., Li, Y., Bathgate, R., Day, M., O'Neill, C. (2003). Ligand-activated signal transduction in the 2-cell embryo. Biology Of Reproduction, 69(1), 106-116. [More Information]

2017

  • Rollo, C., Li, Y., Jin, X., O'Neill, C. (2017). Histone 3 lysine 9 acetylation is a biomarker of the effects of culture on zygotes. Reproduction, 154(4), 375-385. [More Information]
  • Li, Y., O'Neill, C. (2017). Immunological Staining of Global Changes in DNA Methylation in the Early Mammalian Embryo. Methods in Molecular Biology, 1605, 161-169. [More Information]
  • Celik-Uzuner, S., Li, Y., Peters, L., O'Neill, C. (2017). Measurement of global DNA methylation levels by flow cytometry in mouse fibroblasts. In Vitro Cellular & Developmental Biology. Animal, 53(1), 1-6. [More Information]

2016

  • Li, Y., Seah, M., O'Neill, C. (2016). Mapping global changes in nuclear cytosine base modifications in the early mouse embryo. Reproduction, 151(2), 83-95. [More Information]

2015

  • Salvaing, J., Li, Y., Beaujean, N., O'Neill, C. (2015). Determinants of valid measurements of global changes in 5'-methylcytosine and 5'-hydroxymethylcytosine by immunolocalisation in the early embryo. Reproduction, Fertility and Development, 27(5), 755-764. [More Information]
  • O'Neill, C., Li, Y., Jin, X. (2015). Survival Signalling in the Preimplantation Embryo. In Henry J. Leese, Daniel R. Brison (Eds.), Cell Signaling During Mammalian Early Embryo Development, (pp. 129-149). New York: Springer Science+Business Media. [More Information]
  • Celik, S., Li, Y., O'Neill, C. (2015). The effect of DNA damage on the pattern of immune-detectable DNA methylation in mouse embryonic fibroblasts. Experimental Cell Research, 339(1), 20-34. [More Information]

2014

  • Wong, J., Jack, M., Li, Y., O'Neill, C. (2014). The Epigenetic Bivalency of Core Pancreatic b-Cell Transcription Factor Genes within Mouse Pluripotent Embryonic Stem Cells Is Not Affected by Knockdown of the Polycomb Repressive Complex 2, SUZ12. PloS One, 9(5), 1-12. [More Information]
  • Celik, S., Li, Y., O'Neill, C. (2014). The Exit of Mouse Embryonic Fibroblasts from the Cell-Cycle Changes the Nature of Solvent Exposure of the 5'-Methylcytosine Epitope within Chromatin. PloS One, 9(4), 1-12. [More Information]

2013

  • Li, Y., O'Neill, C. (2013). 5'-methylcytosine and 5'-hydroxymethylcytosine Each Provide Epigenetic Information to the Mouse Zygote. PloS One, 8(5), 1-9. [More Information]

2012

  • Li, Y., O'Neill, C. (2012). Persistence of Cytosine Methylation of DNA following Fertilisation in the Mouse. PloS One, 7(1), 1-11. [More Information]
  • O'Neill, C., Li, Y., Jin, X. (2012). Survival signaling in the preimplantation embryo. Theriogenology, 77(4), 773-784. [More Information]

2011

  • Mu, X., Jin, X., Farnham, M., Li, Y., O'Neill, C. (2011). DNA Damage-Sensing Kinases Mediate the Mouse 2-Cell Embryo's Response to Genotoxic Stress. Biology Of Reproduction, 85(3), 524-535. [More Information]

2010

  • Beardsley, A., Li, Y., O'Neill, C. (2010). Characterization of a diverse secretome generated by the mouse preimplantation embryo in vitro. Reproductive Biology and Endocrinology, 8(71), 1-10. [More Information]

2009

  • Li, Y., O'Neill, C., Day, M. (2009). Activation of a Chloride Channel by a Trophic Ligand Is Required for Development of the Mouse Preimplantation Embryo In Vitro. Biology Of Reproduction, 81(4), 759-767. [More Information]

2007

  • Li, Y., Day, M., O'Neill, C. (2007). Autocrine activation of ion currents in the two-cell mouse embryo. Experimental Cell Research, 313(13), 2786-2794. [More Information]
  • Li, Y., Chandrakanthan, V., Day, M., O'Neill, C. (2007). Direct evidence for the action of phosphatidylinositol (3,4,5)-trisphosphate-mediated signal transduction in the 2-cell mouse embryo. Biology Of Reproduction, 77(5), 813-821. [More Information]
  • Gottlieb, D., Micklethwaite, K., Bradstock, K., Li, Y. (2007). Rapid expansion of tumor-reactive cells from HLA-matched siblings for adoptive immunotherapy of melanoma. Cytotherapy, 9(2), 133-143. [More Information]

2003

  • Lu, D., Li, Y., Bathgate, R., Day, M., O'Neill, C. (2003). Ligand-activated signal transduction in the 2-cell embryo. Biology Of Reproduction, 69(1), 106-116. [More Information]
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