Dr Yiping Wang

Senior Research Fellow
Medicine, Westmead Clinical School
Westmead Millennium Institute for Medical Research

Telephone +61 2 9845 6877

Map

Selected grants

2014

  • Therapeutic potential of peritoneal mononuclear phagocytes from peritoneal dialysis patients; Wang Y, Harris D, Yi S; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Defining the role of the major subsets of renal mononuclear phogocytes; Harris D, Wang Y; National Health and Medical Research Council (NHMRC)/Project Grants.

2011

  • Redefining the role of macrophages in atherosclerosis: macrophage subset role in plaque stability; Fletcher J, Wang Y; National Health and Medical Research Council (NHMRC)/Project Grants.
  • The BD Influx High Speed Cell Sorter; Cunningham A, George J, Rizos H, Clarke C, Reddel R, Kefford R, North K, Stewart G, Jones C, Tam P, Alexander S, Gottlieb D, Bradstock K, Bryan T, Booth D, Bendall L, Brilot-Turville F, Hebbard L, Cooper S, Wang Y, Wang X; National Health and Medical Research Council (NHMRC)/Equipment Grants.

2010

  • The BD Influx High Speed Cell Sorter; Kefford R, Cunningham A, Bendall L, Clarke C, Harris D, Alexander S, Tam P, Sorrell T, Iredell J, Bryan T, Rizos H, Wang Y, Hebbard L; National Health and Medical Research Council (NHMRC)/Equipment Grants.
  • Optimising the therapeutic efficacy of anti-inflammatory macrophages for use in chronic kidney diseases; Wang Y, Harris D; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Gamm-Delta Tregs, CD8 Tregs and selected natural Tregs to treat renal injury; Alexander S, Harris D, Wang Y, Wang Y; National Health and Medical Research Council (NHMRC)/Project Grants.

2009

  • DNA vaccination using chemokine and costimulatory pathways as a treatment for chronic kidney disease; Harris D, Alexander S, Wang Y, Wang Y; National Health and Medical Research Council (NHMRC)/Project Grants.

2007

  • Treatment of Diverse Renal Diseases with Regulatory Cells; Harris D, Alexander S, Wang Y, Wang Y; National Health and Medical Research Council (NHMRC)/Project Grants.
  • Kidney Injury as a determinant of macrophage phenotype and efficacy for treating chronic kidney disease (CKD); Wang Y, Harris D; National Health and Medical Research Council (NHMRC)/Project Grants.

2004

  • Costimulation in progressive non-immune tubulointerstitial renal disease; Harris D, Alexander S, Wang Y; National Health and Medical Research Council (NHMRC)/Project Grants.

2002

  • Effector and regulatory interstitial inflammatory cells in chronic proteinuric renal disease; Harris D, Wang Y; National Health and Medical Research Council (NHMRC)/Project Grants.

2000

  • Modification of tubule cell cytokines regulating interstitial inflammation in chronic proteinuric renal disease; Harris D, Wang Y; National Health and Medical Research Council (NHMRC)/Project Grants.

Selected publications

Download citations: PDF RTF Endnote

Book Chapters

  • Lee, V., Cao, Q., Wang, Y., Harris, D. (2011). Role of Macrophages in Renal Injury,Repair and Regeneration. In Michael S. Goligorsky (Eds.), Regenerative Nephrology, (pp. 125-139). USA: Elsevier.

Journals

  • Zheng, D., Wen, L., Li, C., Peng, A., Cao, Q., Wang, Y., Harris, D. (2014). Adoptive transfer of bone marrow dendritic cells failed to localize in the renal cortex and to improve renal injury in adriamycin nephropathy. Nephron Experimental Nephrology, 126(1), 8-15. [More Information]
  • Cao, Q., Wang, Y., Zheng, D., Sun, Y., Wang, C., Wang, X., Lee, V., Wang, Y., Zheng, G., Tan, T., Harris, D., et al (2014). Failed renoprotection by alternatively activated macrophages from bone marrow due to proliferation-dependent phenotype switch in vivo. Kidney International, 85(4), 794-806. [More Information]
  • Wang, Y., Wang, Y., Wang, Y., Zheng, G., Tan, T., Lee, S., Zhang, J., Zhang, G., Hu, M., Wang, C., Cao, Q., Zhao, Y., Harris, D., et al (2014). Regulatory T cells require renal antigen recognition through the TCR to protect against injury in nephritis. International Journal of Clinical and Experimental Pathology, 7(1), 38-47.
  • Tian, X., Zhang, J., Tan, T., Lyons, G., Zhao, H., Niu, B., Lee, S., Tsatralis, T., Zhao, Y., Wang, Y., Cao, Q., Wang, C., Wang, Y., Lee, V., Zheng, G., Harris, D., et al (2013). Association of beta catenin with P-Smad3 but not LEF-1 dissociates in vitro profibrotic from anti-inflammatory effects of TGF- beta1. Journal of Cell Science, 126(1), 67-76. [More Information]
  • Wang, Y., Zhou, J., Wang, Y., Watson, D., Zhang, G., Hu, M., Wu, H., Zheng, G., Wang, Y., Durkan, A., Harris, D., Alexander, S. (2013). Daedalic DNA vaccination against self antigens as a treatment for chronic kidney disease. International Journal of Clinical and Experimental Pathology, 6(3), 326-333. [More Information]
  • Medbury, H., James, V., Ngo, J., Hitos, K., Wang, Y., Harris, D., Fletcher, J. (2013). Differing association of macrophage subsets with atherosclerotic plaque stability. International Angiology, 32(1), 74-84. [More Information]
  • Lu, J., Cao, Q., Zheng, D., Sun, Y., Wang, C., Yu, X., Wang, Y., Lee, V., Zheng, G., Tan, T., Wang, X., Harris, D., Wang, Y., et al (2013). Discrete functions of M2a and M2c macrophage subsets determine their relative efficacy in treating chronic kidney disease. Kidney International, 84(4), 745-755. [More Information]
  • Li, Q., Wang, Y., Wang, Y., Zhou, Q., Chen, K., Wang, Y., Wei, W., Wang, Y. (2013). Distinct different sensitivity of Treg and Th17 cells to Fas-mediated apoptosis signaling in patients with acute coronary syndrome. International Journal of Clinical and Experimental Pathology, 6(2), 297-307. [More Information]
  • Wang, Y., Wang, Y., Wang, Y., Zheng, G., Zhang, G., Zhou, J., Tan, T., Cao, Q., Hu, M., Watson, D., Wu, H., Zheng, D., Wang, C., Harris, D., et al (2013). DNA vaccine encoding CD40 targeted to dendritic cells in situ prevents the development of Heymann nephritis in rats. Kidney International, 83(2), 223-232. [More Information]
  • Tan, T., Zheng, G., Hsu, T., Lee, S., Zhang, J., Zhao, Y., Tian, X., Wang, Y., Wang, Y., Cao, Q., Wang, Y., Lee, V., Wang, C., Zheng, D., Alexander, S., Harris, D., et al (2013). Matrix metalloproteinase-9 of tubular and macrophage origin contributes to the pathogenesis of renal fibrosis via macrophage recruitment through osteopontin cleavage. Laboratory Investigation, 93(4), 434-449. [More Information]
  • Cao, Q., Wang, Y., Harris, D. (2013). Pathogenic and protective role of macrophages in kidney disease. American Journal of Physiology: Renal Physiology (Print), 305(1), F3-F11. [More Information]
  • Li, Q., Wang, Y., Yu, F., Wang, Y., Zhang, C., Hu, C., Wu, Z., Xu, X., Hu, S. (2013). Peripheral Th17/Treg imbalance in patients with atherosclerotic cerebral infarction. International Journal of Clinical and Experimental Pathology, 6(6), 1015-1027.
  • Lee, V., Wang, Y., Harris, D. (2013). The Role of the Immune System in the Pathogenesis of Hypertension. Current Hypertension Reviews, 9(1), 76-84. [More Information]
  • Wang, Y., Zhang, G., Hu, M., Polhill, T., Sawyer, A., Zhou, J., Saito, M., Watson, D., Wu, H., Wang, Y., Wang, X., Wang, Y., Harris, D., Alexander, S. (2012). CD8+ Regulatory T Cells Induced by T Cell Vaccination Protect Against Autoimmune Nephritis. Journal of the American Society of Nephrology, 23(6), 1058-1067. [More Information]
  • Polhill, T., Zhang, G., Hu, M., Sawyer, A., Zhou, J., Saito, M., Webster, K., Wang, Y., Wang, Y., Grey, S., Harris, D., Alexander, S., Wang, Y., et al (2012). IL-2/IL-2Ab Complexes Induce Regulatory T Cell Expansion and Protect against Proteinuric CKD. Journal of the American Society of Nephrology, 23(8), 1303-1308. [More Information]
  • Zheng, D., Cao, Q., Lee, V., Wang, Y., Zheng, G., Wang, Y., Tan, T., Wang, C., Alexander, S., Harris, D., Wang, Y. (2012). Lipopolysaccharide-pretreated plasmacytoid dendritic cells ameliorate experimental chronic kidney disease. Kidney International. [More Information]
  • Wang, Y., McRae, J., Robson, S., Cowan, P., Zhang, G., Hu, M., Polhill, T., Wang, Y., Zheng, G., Wang, Y., Lee, V., Harris, D., Alexander, S., et al (2012). Regulatory T cells participate in CD39-mediated protection from renal injury. European Journal of Immunology, 42(9), 2441-2451. [More Information]
  • Cao, Q., Wang, C., Zheng, D., Wang, Y., Lee, V., Wang, Y., Zheng, G., Tan, T., Yu, D., Alexander, S., Harris, D., Wang, Y. (2011). IL-25 Induces M2 Macrophages and Reduces Renal Injury in Proteinuric Kidney Disease. Journal of the American Society of Nephrology, 22(7), 1229-1239. [More Information]
  • Cao, Q., Zheng, D., Wang, Y., Harris, D. (2011). Macrophages and Dendritic Cells for Treating Kidney Disease. Nephron Experimental Nephrology, 117(3), e47-e52. [More Information]
  • Wang, Y., Harris, D. (2011). Macrophages in renal disease. Journal of the American Society of Nephrology, 22(1), 21-27. [More Information]
  • Sun, Y., Yu, H., Zheng, D., Cao, Q., Wang, Y., Harris, D., Wang, Y. (2011). Sudan Black B Reduces Autofluorescence in Murine Renal Tissue. Archives of Pathology and Laboratory Medicine, 135(10), 1335-1342. [More Information]
  • Zheng, D., Wang, Y., Cao, Q., Lee, V., Zheng, G., Sun, Y., Tan, T., Wang, Y., Alexander, S., Harris, D. (2011). Transfused Macrophages Ameliorate Pancreatic and Renal Injury in Murine Diabetes Mellitus. Nephron Experimental Nephrology, 118(4), e87-e99. [More Information]
  • Li, Q., Zhai, Z., Xu, X., Shen, Y., Zhang, A., Sun, Z., Liu, H., Geng, L., Wang, Y. (2010). Decrease of CD4(+)CD25(+) regulatory T cells and TGF-beta at early immune reconstitution is associated to the onset and severity of graft-versus-host disease following allogeneic haematogenesis stem cell transplantation. Leukemia Research: clinical and laboratory studies, 34(9), 1158-1168. [More Information]
  • Cao, Q., Wang, Y., Zheng, D., Sun, Y., Wang, Y., Lee, V., Zheng, G., Tan, T., Ince, J., Alexander, S., Harris, D. (2010). IL-10/TGF-{beta}-Modified Macrophages Induce Regulatory T Cells and Protect against Adriamycin Nephrosis. Journal of the American Society of Nephrology, 21(6), 933-942. [More Information]
  • Tan, T., Zheng, G., Hsu, T., Wang, Y., Lee, V., Tian, X., Wang, Y., Cao, Q., Wang, Y., Harris, D. (2010). Macrophage Matrix Metalloproteinase-9 Mediates Epithelial-Mesenchymal Transition in Vitro in Murine Renal Tubular Cells. The American Journal of Pathology: cellular and molecular biology of disease, 176(3), 1256-1270. [More Information]
  • Lee, V., Qin, X., Wang, Y., Zheng, G., Wang, Y., Wang, Y., Ince, J., Tan, T., Kairaitis, L., Alexander, S., Harris, D. (2010). The CD40-CD154 co-stimulation pathway mediates innate immune injury in adriamycin nephrosis. Nephrology, Dialysis, Transplantation, 25(3), 717-730. [More Information]
  • Li, Q., Wang, Y., Chen, K., Zhou, Q., Wei, W., Wang, Y., Wang, Y. (2010). The role of oxidized low-density lipoprotein in breaking peripheral Th17/Treg balance in patients with acute coronary syndrome. Biochemical and Biophysical Research Communications, 394(3), 836-842.
  • Watson, D., Zheng, G., Wu, H., Wang, Y., Wang, Y., Harris, D., Alexander, S. (2009). CCL2 DNA vaccine to treat renal disease. The International Journal of Biochemistry and Cell Biology, 41(4), 729-732. [More Information]
  • Zheng, G., Lyons, J., Tan, T., Wang, Y., Hsu, T., Min, D., Succar, L., Rangan, G., Hu, M., Henderson, B., Alexander, S., Harris, D. (2009). Disruption of E-Cadherin by Matrix Metalloproteinase Directly Mediates Epithelial-Mesenchymal Transition Downstream of Transforming Growth Factor-{beta}1 in Renal Tubular Epithelial Cells. The American Journal of Pathology: cellular and molecular biology of disease, 175(2), 580-591. [More Information]
  • Rangan, G., Wang, Y., Harris, D. (2009). NF-kappaB signalling in chronic kidney disease. Frontiers in Bioscience, 14, 3496-3522. [More Information]
  • Wang, Y., Wang, Y., Cai, Q., Zheng, G., Lee, V., Zheng, D., Li, X., Tan, T., Harris, D. (2008). By Homing to the Kidney, Activated Macrophages Potently Exacerbate Renal Injury. The American Journal of Pathology: cellular and molecular biology of disease, 172(6), 1491-1499. [More Information]
  • Wu, J., Yi, S., Ouyang, L., Jimenez, E., Simond, D., Wang, W., Wang, Y., Hawthorne, W., O'Connell, P. (2008). In Vitro Expanded Human CD4+CD25+ Regulatory T Cells are Potent Suppressors of T-Cell-Mediated Xenogeneic Responses. Transplantation, 85(12), 1841-1848. [More Information]
  • Lee, V., Wang, Y., Wang, Y., Zheng, D., Polhill, T., Cao, Q., Wu, H., Alexander, I., Alexander, S., Harris, D. (2008). Regulatory immune cells in kidney disease. American Journal of Physiology: Renal Physiology (Print), 295(2), F335-F342. [More Information]
  • Wang, Y., Hu, M., Wang, Y., Polhill, T., Zhang, G., Wang, Y., Lee, V., Harris, D., Alexander, S. (2008). Regulatory T Cells in Renal Disease. International Journal of Clinical and Experimental Medicine, 1(4), 294-304. [More Information]
  • Zhai, Z., Sun, Z., Li, Q., Zhang, A., Liu, H., Xu, J., Xu, X., Geng, L., Harris, D., Hu, S., Wang, Y. (2007). Correlation of the CD4(+)CD25(high) T-regulatory cells in recipients and their corresponding donors to acute GVHD. Transplant International, 20(5), 440-446.
  • Zhimin, Z., Zimin, S., Qing, L., Aimei, Z., Huilan, L., Jingwei, X., Xiucai, X., Liangquan, G., Harris, D., Shilian, H., Wang, Y. (2007). Correlation of the CD4+CD25+ high T regulatory cells in recipients and their corresponding donors to acute GVHD. Transplant International, 20(5), 440-446. [More Information]
  • Huiling, W., Wang, Y., Wang, Y., Hu, M., Zhang, G., Knight, J., Harris, D., Alexander, S. (2007). Depletion of gammadelta T cells exacerbates murine adriamycin nephropathy. Journal of the American Society of Nephrology, 18(4), 1180-1189. [More Information]
  • Wang, Y., Wang, Y., Zheng, G., Lee, V., Ouyang, L., Chang, D., Mahajan, D., Coombs, J., Wang, Y., Alexander, S., Harris, D. (2007). Ex vivo programmed macrophages ameliorate experimental chronic inflammatory renal disease. Kidney International, 72(3), 290-299. [More Information]
  • Qin, X., Lee, V., Wang, Y., Zheng, G., Wang, Y., Alexander, S., Harris, D. (2006). A protective role for programmed death 1 in progression of murine adriamycin nephropathy. Kidney International, 70, 1244-1250. [More Information]
  • Lee, V., Wang, Y., Qin, X., Wang, Y., Zheng, G., Mahajan, D., Coombes, J., Rangan, G., Alexander, S., Harris, D. (2006). Adriamycin nephropathy in severe combined immunodeficient (SCID) mice. Nephrology, Dialysis, Transplantation. [More Information]
  • Mahajan, D., Wang, Y., Qin, X., Wang, Y., Zheng, G., Wang, Y., Alexander, S., Harris, D. (2006). CD4+CD25+ Regulatory T Cells Protect against Injury in an Innate Murine Model of Chronic Kidney Disease. Journal of the American Society of Nephrology, 17(10), 2731-2741. [More Information]
  • Zheng, G., Wang, Y., XIANG, S., Tay, Y., Wu, H., Watson, D., Coombes, J., Rangan, G., Alexander, S., Harris, D. (2006). DNA vaccination with CCL2 DNA modified by the addition of an adjuvant epitope protects against "nonimmune" toxic renal injury. Journal of the American Society of Nephrology, 17(2), 465-474. [More Information]
  • Allan, C., Wang, Y., Jimenez, M., Marshan, B., Spaliviero, J., Illingworth, P., Handelsman, D. (2006). Follicle-stimulating hormone increases primordial follicle reserve in mature female hypogonadal mice. Journal of Endocrinology, 188(3), 549-557. [More Information]
  • Wang, Y., Zhang, G., Wang, Y., Hu, M., Wu, H., Watson, D., Hori, S., Alexander, I., Harris, D., Alexander, S. (2006). Foxp3-transduced polyclonal regulatory T cells protect against chronic renal injury from adriamycin. Journal of the American Society of Nephrology, 17(3), 697-706. [More Information]
  • Zheng, G., Zheng, L., Wang, Y., Wu, H., Kairaitis, L., Zhang, C., Tay, Y., Wang, Y., Alexander, S., Harris, D. (2006). NK cells do not mediate renal injury in murine adriamycin nephropathy. Kidney International, 69(7), 1159-1165. [More Information]
  • Zhu, G., Wang, Y., Wang, J., Tay, Y., Yung, T., Rangan, G., Harris, D. (2006). Significance of CD25 positive cells and macrophages in noncrescentic IgA nephropathy. Renal Failure, 28(3), 229-235. [More Information]
  • Chew, C., Potter, S., Wang, B., Wang, Y., Shaw, C., Dwyer, D., Saksena, N. (2005). Assessment of drug resistance mutations in plasma and peripheral blood mononuclear cells at different plasma viral loads in patients receiving HAART. Journal Of Clinical Virology, 33(3), 206-216. [More Information]
  • Tay, Y., Wang, Y., Kairaitis, L., Rangan, G., Zhang, C., Harris, D. (2005). Can murine diabetic nephropathy be separated from superimposed acute renal failure? Kidney International, 68(1), 391-398. [More Information]
  • Rangan, G., Wang, Y., Tay, Y., Harris, D. (2005). Differential effects of albumin on cytokine gene expression in proximal tubular epithelial cells. Nephrology, Dialysis, Transplantation, 20(5), 1013-1014.
  • Wu, H., Wang, Y., Tay, Y., Zheng, G., Zhang, C., Alexander, S., Harris, D. (2005). DNA vaccination with naked DNA encoding MCP-1 and RANTES protects against renal injury in adriamycin nephropathy. Kidney International, 67(6), 2178-2186. [More Information]
  • Rangan, G., Wang, Y., Harris, D., Tay, Y., Coombes, J. (2005). Effect of nephrotoxins on tubulointerstitial injury and NF-kappaB activation in Adriamycin nephropathy. Renal Failure, 27(5), 609-14. [More Information]
  • Kairaitis, L., Wang, Y., Gassmann, M., Tay, Y., Harris, D. (2005). HIF-1α expression follows microvascular loss in advanced murine adriamycin nephrosis. American Journal of Physiology: Renal Physiology (Print), 288(1), F198-F206. [More Information]
  • Wang, Y., Mahajan, D., Tay, Y., Bao, B., Spicer, T., Kairaitis, L., Rangan, G., Harris, D. (2005). Partial depletion of macrophages by ED7 reduces renal injury in Adriamycin nephropathy. Nephrology, 10(5), 470-7. [More Information]
  • Zheng, G., Wang, Y., Mahajan, D., Qin, X., Wang, Y., Wang, Y., Alexander, S., Harris, D. (2005). The role of tubulointerstitial inflammation. Kidney International, 67(S94), S96-S100. [More Information]
  • Wang, Y., Tay, Y., Harris, D. (2004). Proximal Tubule Cells Stimulated By Lipopolysaccharide Inhibit Macrophage Activation. Kidney International, 66(2), 655-62.
  • Sadlier, D., Connolly, S., Kieran, N., Roxburgh, S., Brazil, D., Kairaitis, L., Wang, Y., Harris, D., Doran, P., Brady, H. (2004). Sequential Extracellular Matrix-Focused And Baited-Global Cluster Analysis Of Serial Transcriptomic Profiles Identifies Candidate Modulators Of Renal Tubulointerstitial Fibrosis In Murine Adriamycin-Induced Nephropathy. Journal of Biological Chemistry, 279(28), 29670-80.
  • Kairaitis, L., Wang, Y., Zheng, L., Tay, Y., Wang, Y., Harris, D. (2003). Blockade of CD40-CD40 ligand protects against renal injury in chronic proteinuric renal disease. Kidney International, 64(4), 1265-1272.
  • Wang, Y., Harris, D., Rangan, G. (2002). Dietary Quercetin Augments activator Protein-1 and Does Not Reduce Nuclear Factor-KB in the Renal Cortex of Rats with Established Chronic Glomerular Disease. Nephron Journals, 90(3), 313-319.
  • Wang, Y., Yi, S., Tay, Y., Feng, X., Kairaitis, L., Harris, D. (2002). Transfection of tubule cells with Fas ligand causes leukocyte apoptosis. Kidney International, 61(4), 1303-1311.

Conferences

  • Wang, Y., Zhang, G., Wang, Y., Hu, M., Wu, H., Watson, D., Harris, D., Alexander, S. (2006). T cell vaccination protects against active Heymann nephritis: A CD8 T cell mechanism. 24th Annual Scientific Meeting of the Transplantation Society of Australia and New Zealand (2006), Australia: Nature Publishing Group.
  • Zhang, G., Hu, M., Wang, Y., Osvath, S., Sedger, L., Alexander, S. (2005). IL-15 required for DST induced tolerance across a major class I mismatch. 6th American Transplant Congress, Oxford, UK: Blackwell Publishing Professionals.

2014

  • Zheng, D., Wen, L., Li, C., Peng, A., Cao, Q., Wang, Y., Harris, D. (2014). Adoptive transfer of bone marrow dendritic cells failed to localize in the renal cortex and to improve renal injury in adriamycin nephropathy. Nephron Experimental Nephrology, 126(1), 8-15. [More Information]
  • Cao, Q., Wang, Y., Zheng, D., Sun, Y., Wang, C., Wang, X., Lee, V., Wang, Y., Zheng, G., Tan, T., Harris, D., et al (2014). Failed renoprotection by alternatively activated macrophages from bone marrow due to proliferation-dependent phenotype switch in vivo. Kidney International, 85(4), 794-806. [More Information]
  • Wang, Y., Wang, Y., Wang, Y., Zheng, G., Tan, T., Lee, S., Zhang, J., Zhang, G., Hu, M., Wang, C., Cao, Q., Zhao, Y., Harris, D., et al (2014). Regulatory T cells require renal antigen recognition through the TCR to protect against injury in nephritis. International Journal of Clinical and Experimental Pathology, 7(1), 38-47.

2013

  • Tian, X., Zhang, J., Tan, T., Lyons, G., Zhao, H., Niu, B., Lee, S., Tsatralis, T., Zhao, Y., Wang, Y., Cao, Q., Wang, C., Wang, Y., Lee, V., Zheng, G., Harris, D., et al (2013). Association of beta catenin with P-Smad3 but not LEF-1 dissociates in vitro profibrotic from anti-inflammatory effects of TGF- beta1. Journal of Cell Science, 126(1), 67-76. [More Information]
  • Wang, Y., Zhou, J., Wang, Y., Watson, D., Zhang, G., Hu, M., Wu, H., Zheng, G., Wang, Y., Durkan, A., Harris, D., Alexander, S. (2013). Daedalic DNA vaccination against self antigens as a treatment for chronic kidney disease. International Journal of Clinical and Experimental Pathology, 6(3), 326-333. [More Information]
  • Medbury, H., James, V., Ngo, J., Hitos, K., Wang, Y., Harris, D., Fletcher, J. (2013). Differing association of macrophage subsets with atherosclerotic plaque stability. International Angiology, 32(1), 74-84. [More Information]
  • Lu, J., Cao, Q., Zheng, D., Sun, Y., Wang, C., Yu, X., Wang, Y., Lee, V., Zheng, G., Tan, T., Wang, X., Harris, D., Wang, Y., et al (2013). Discrete functions of M2a and M2c macrophage subsets determine their relative efficacy in treating chronic kidney disease. Kidney International, 84(4), 745-755. [More Information]
  • Li, Q., Wang, Y., Wang, Y., Zhou, Q., Chen, K., Wang, Y., Wei, W., Wang, Y. (2013). Distinct different sensitivity of Treg and Th17 cells to Fas-mediated apoptosis signaling in patients with acute coronary syndrome. International Journal of Clinical and Experimental Pathology, 6(2), 297-307. [More Information]
  • Wang, Y., Wang, Y., Wang, Y., Zheng, G., Zhang, G., Zhou, J., Tan, T., Cao, Q., Hu, M., Watson, D., Wu, H., Zheng, D., Wang, C., Harris, D., et al (2013). DNA vaccine encoding CD40 targeted to dendritic cells in situ prevents the development of Heymann nephritis in rats. Kidney International, 83(2), 223-232. [More Information]
  • Tan, T., Zheng, G., Hsu, T., Lee, S., Zhang, J., Zhao, Y., Tian, X., Wang, Y., Wang, Y., Cao, Q., Wang, Y., Lee, V., Wang, C., Zheng, D., Alexander, S., Harris, D., et al (2013). Matrix metalloproteinase-9 of tubular and macrophage origin contributes to the pathogenesis of renal fibrosis via macrophage recruitment through osteopontin cleavage. Laboratory Investigation, 93(4), 434-449. [More Information]
  • Cao, Q., Wang, Y., Harris, D. (2013). Pathogenic and protective role of macrophages in kidney disease. American Journal of Physiology: Renal Physiology (Print), 305(1), F3-F11. [More Information]
  • Li, Q., Wang, Y., Yu, F., Wang, Y., Zhang, C., Hu, C., Wu, Z., Xu, X., Hu, S. (2013). Peripheral Th17/Treg imbalance in patients with atherosclerotic cerebral infarction. International Journal of Clinical and Experimental Pathology, 6(6), 1015-1027.
  • Lee, V., Wang, Y., Harris, D. (2013). The Role of the Immune System in the Pathogenesis of Hypertension. Current Hypertension Reviews, 9(1), 76-84. [More Information]

2012

  • Wang, Y., Zhang, G., Hu, M., Polhill, T., Sawyer, A., Zhou, J., Saito, M., Watson, D., Wu, H., Wang, Y., Wang, X., Wang, Y., Harris, D., Alexander, S. (2012). CD8+ Regulatory T Cells Induced by T Cell Vaccination Protect Against Autoimmune Nephritis. Journal of the American Society of Nephrology, 23(6), 1058-1067. [More Information]
  • Polhill, T., Zhang, G., Hu, M., Sawyer, A., Zhou, J., Saito, M., Webster, K., Wang, Y., Wang, Y., Grey, S., Harris, D., Alexander, S., Wang, Y., et al (2012). IL-2/IL-2Ab Complexes Induce Regulatory T Cell Expansion and Protect against Proteinuric CKD. Journal of the American Society of Nephrology, 23(8), 1303-1308. [More Information]
  • Zheng, D., Cao, Q., Lee, V., Wang, Y., Zheng, G., Wang, Y., Tan, T., Wang, C., Alexander, S., Harris, D., Wang, Y. (2012). Lipopolysaccharide-pretreated plasmacytoid dendritic cells ameliorate experimental chronic kidney disease. Kidney International. [More Information]
  • Wang, Y., McRae, J., Robson, S., Cowan, P., Zhang, G., Hu, M., Polhill, T., Wang, Y., Zheng, G., Wang, Y., Lee, V., Harris, D., Alexander, S., et al (2012). Regulatory T cells participate in CD39-mediated protection from renal injury. European Journal of Immunology, 42(9), 2441-2451. [More Information]

2011

  • Cao, Q., Wang, C., Zheng, D., Wang, Y., Lee, V., Wang, Y., Zheng, G., Tan, T., Yu, D., Alexander, S., Harris, D., Wang, Y. (2011). IL-25 Induces M2 Macrophages and Reduces Renal Injury in Proteinuric Kidney Disease. Journal of the American Society of Nephrology, 22(7), 1229-1239. [More Information]
  • Cao, Q., Zheng, D., Wang, Y., Harris, D. (2011). Macrophages and Dendritic Cells for Treating Kidney Disease. Nephron Experimental Nephrology, 117(3), e47-e52. [More Information]
  • Wang, Y., Harris, D. (2011). Macrophages in renal disease. Journal of the American Society of Nephrology, 22(1), 21-27. [More Information]
  • Lee, V., Cao, Q., Wang, Y., Harris, D. (2011). Role of Macrophages in Renal Injury,Repair and Regeneration. In Michael S. Goligorsky (Eds.), Regenerative Nephrology, (pp. 125-139). USA: Elsevier.
  • Sun, Y., Yu, H., Zheng, D., Cao, Q., Wang, Y., Harris, D., Wang, Y. (2011). Sudan Black B Reduces Autofluorescence in Murine Renal Tissue. Archives of Pathology and Laboratory Medicine, 135(10), 1335-1342. [More Information]
  • Zheng, D., Wang, Y., Cao, Q., Lee, V., Zheng, G., Sun, Y., Tan, T., Wang, Y., Alexander, S., Harris, D. (2011). Transfused Macrophages Ameliorate Pancreatic and Renal Injury in Murine Diabetes Mellitus. Nephron Experimental Nephrology, 118(4), e87-e99. [More Information]

2010

  • Li, Q., Zhai, Z., Xu, X., Shen, Y., Zhang, A., Sun, Z., Liu, H., Geng, L., Wang, Y. (2010). Decrease of CD4(+)CD25(+) regulatory T cells and TGF-beta at early immune reconstitution is associated to the onset and severity of graft-versus-host disease following allogeneic haematogenesis stem cell transplantation. Leukemia Research: clinical and laboratory studies, 34(9), 1158-1168. [More Information]
  • Cao, Q., Wang, Y., Zheng, D., Sun, Y., Wang, Y., Lee, V., Zheng, G., Tan, T., Ince, J., Alexander, S., Harris, D. (2010). IL-10/TGF-{beta}-Modified Macrophages Induce Regulatory T Cells and Protect against Adriamycin Nephrosis. Journal of the American Society of Nephrology, 21(6), 933-942. [More Information]
  • Tan, T., Zheng, G., Hsu, T., Wang, Y., Lee, V., Tian, X., Wang, Y., Cao, Q., Wang, Y., Harris, D. (2010). Macrophage Matrix Metalloproteinase-9 Mediates Epithelial-Mesenchymal Transition in Vitro in Murine Renal Tubular Cells. The American Journal of Pathology: cellular and molecular biology of disease, 176(3), 1256-1270. [More Information]
  • Lee, V., Qin, X., Wang, Y., Zheng, G., Wang, Y., Wang, Y., Ince, J., Tan, T., Kairaitis, L., Alexander, S., Harris, D. (2010). The CD40-CD154 co-stimulation pathway mediates innate immune injury in adriamycin nephrosis. Nephrology, Dialysis, Transplantation, 25(3), 717-730. [More Information]
  • Li, Q., Wang, Y., Chen, K., Zhou, Q., Wei, W., Wang, Y., Wang, Y. (2010). The role of oxidized low-density lipoprotein in breaking peripheral Th17/Treg balance in patients with acute coronary syndrome. Biochemical and Biophysical Research Communications, 394(3), 836-842.

2009

  • Watson, D., Zheng, G., Wu, H., Wang, Y., Wang, Y., Harris, D., Alexander, S. (2009). CCL2 DNA vaccine to treat renal disease. The International Journal of Biochemistry and Cell Biology, 41(4), 729-732. [More Information]
  • Zheng, G., Lyons, J., Tan, T., Wang, Y., Hsu, T., Min, D., Succar, L., Rangan, G., Hu, M., Henderson, B., Alexander, S., Harris, D. (2009). Disruption of E-Cadherin by Matrix Metalloproteinase Directly Mediates Epithelial-Mesenchymal Transition Downstream of Transforming Growth Factor-{beta}1 in Renal Tubular Epithelial Cells. The American Journal of Pathology: cellular and molecular biology of disease, 175(2), 580-591. [More Information]
  • Rangan, G., Wang, Y., Harris, D. (2009). NF-kappaB signalling in chronic kidney disease. Frontiers in Bioscience, 14, 3496-3522. [More Information]

2008

  • Wang, Y., Wang, Y., Cai, Q., Zheng, G., Lee, V., Zheng, D., Li, X., Tan, T., Harris, D. (2008). By Homing to the Kidney, Activated Macrophages Potently Exacerbate Renal Injury. The American Journal of Pathology: cellular and molecular biology of disease, 172(6), 1491-1499. [More Information]
  • Wu, J., Yi, S., Ouyang, L., Jimenez, E., Simond, D., Wang, W., Wang, Y., Hawthorne, W., O'Connell, P. (2008). In Vitro Expanded Human CD4+CD25+ Regulatory T Cells are Potent Suppressors of T-Cell-Mediated Xenogeneic Responses. Transplantation, 85(12), 1841-1848. [More Information]
  • Lee, V., Wang, Y., Wang, Y., Zheng, D., Polhill, T., Cao, Q., Wu, H., Alexander, I., Alexander, S., Harris, D. (2008). Regulatory immune cells in kidney disease. American Journal of Physiology: Renal Physiology (Print), 295(2), F335-F342. [More Information]
  • Wang, Y., Hu, M., Wang, Y., Polhill, T., Zhang, G., Wang, Y., Lee, V., Harris, D., Alexander, S. (2008). Regulatory T Cells in Renal Disease. International Journal of Clinical and Experimental Medicine, 1(4), 294-304. [More Information]

2007

  • Zhai, Z., Sun, Z., Li, Q., Zhang, A., Liu, H., Xu, J., Xu, X., Geng, L., Harris, D., Hu, S., Wang, Y. (2007). Correlation of the CD4(+)CD25(high) T-regulatory cells in recipients and their corresponding donors to acute GVHD. Transplant International, 20(5), 440-446.
  • Zhimin, Z., Zimin, S., Qing, L., Aimei, Z., Huilan, L., Jingwei, X., Xiucai, X., Liangquan, G., Harris, D., Shilian, H., Wang, Y. (2007). Correlation of the CD4+CD25+ high T regulatory cells in recipients and their corresponding donors to acute GVHD. Transplant International, 20(5), 440-446. [More Information]
  • Huiling, W., Wang, Y., Wang, Y., Hu, M., Zhang, G., Knight, J., Harris, D., Alexander, S. (2007). Depletion of gammadelta T cells exacerbates murine adriamycin nephropathy. Journal of the American Society of Nephrology, 18(4), 1180-1189. [More Information]
  • Wang, Y., Wang, Y., Zheng, G., Lee, V., Ouyang, L., Chang, D., Mahajan, D., Coombs, J., Wang, Y., Alexander, S., Harris, D. (2007). Ex vivo programmed macrophages ameliorate experimental chronic inflammatory renal disease. Kidney International, 72(3), 290-299. [More Information]

2006

  • Qin, X., Lee, V., Wang, Y., Zheng, G., Wang, Y., Alexander, S., Harris, D. (2006). A protective role for programmed death 1 in progression of murine adriamycin nephropathy. Kidney International, 70, 1244-1250. [More Information]
  • Lee, V., Wang, Y., Qin, X., Wang, Y., Zheng, G., Mahajan, D., Coombes, J., Rangan, G., Alexander, S., Harris, D. (2006). Adriamycin nephropathy in severe combined immunodeficient (SCID) mice. Nephrology, Dialysis, Transplantation. [More Information]
  • Mahajan, D., Wang, Y., Qin, X., Wang, Y., Zheng, G., Wang, Y., Alexander, S., Harris, D. (2006). CD4+CD25+ Regulatory T Cells Protect against Injury in an Innate Murine Model of Chronic Kidney Disease. Journal of the American Society of Nephrology, 17(10), 2731-2741. [More Information]
  • Zheng, G., Wang, Y., XIANG, S., Tay, Y., Wu, H., Watson, D., Coombes, J., Rangan, G., Alexander, S., Harris, D. (2006). DNA vaccination with CCL2 DNA modified by the addition of an adjuvant epitope protects against "nonimmune" toxic renal injury. Journal of the American Society of Nephrology, 17(2), 465-474. [More Information]
  • Allan, C., Wang, Y., Jimenez, M., Marshan, B., Spaliviero, J., Illingworth, P., Handelsman, D. (2006). Follicle-stimulating hormone increases primordial follicle reserve in mature female hypogonadal mice. Journal of Endocrinology, 188(3), 549-557. [More Information]
  • Wang, Y., Zhang, G., Wang, Y., Hu, M., Wu, H., Watson, D., Hori, S., Alexander, I., Harris, D., Alexander, S. (2006). Foxp3-transduced polyclonal regulatory T cells protect against chronic renal injury from adriamycin. Journal of the American Society of Nephrology, 17(3), 697-706. [More Information]
  • Zheng, G., Zheng, L., Wang, Y., Wu, H., Kairaitis, L., Zhang, C., Tay, Y., Wang, Y., Alexander, S., Harris, D. (2006). NK cells do not mediate renal injury in murine adriamycin nephropathy. Kidney International, 69(7), 1159-1165. [More Information]
  • Zhu, G., Wang, Y., Wang, J., Tay, Y., Yung, T., Rangan, G., Harris, D. (2006). Significance of CD25 positive cells and macrophages in noncrescentic IgA nephropathy. Renal Failure, 28(3), 229-235. [More Information]
  • Wang, Y., Zhang, G., Wang, Y., Hu, M., Wu, H., Watson, D., Harris, D., Alexander, S. (2006). T cell vaccination protects against active Heymann nephritis: A CD8 T cell mechanism. 24th Annual Scientific Meeting of the Transplantation Society of Australia and New Zealand (2006), Australia: Nature Publishing Group.

2005

  • Chew, C., Potter, S., Wang, B., Wang, Y., Shaw, C., Dwyer, D., Saksena, N. (2005). Assessment of drug resistance mutations in plasma and peripheral blood mononuclear cells at different plasma viral loads in patients receiving HAART. Journal Of Clinical Virology, 33(3), 206-216. [More Information]
  • Tay, Y., Wang, Y., Kairaitis, L., Rangan, G., Zhang, C., Harris, D. (2005). Can murine diabetic nephropathy be separated from superimposed acute renal failure? Kidney International, 68(1), 391-398. [More Information]
  • Rangan, G., Wang, Y., Tay, Y., Harris, D. (2005). Differential effects of albumin on cytokine gene expression in proximal tubular epithelial cells. Nephrology, Dialysis, Transplantation, 20(5), 1013-1014.
  • Wu, H., Wang, Y., Tay, Y., Zheng, G., Zhang, C., Alexander, S., Harris, D. (2005). DNA vaccination with naked DNA encoding MCP-1 and RANTES protects against renal injury in adriamycin nephropathy. Kidney International, 67(6), 2178-2186. [More Information]
  • Rangan, G., Wang, Y., Harris, D., Tay, Y., Coombes, J. (2005). Effect of nephrotoxins on tubulointerstitial injury and NF-kappaB activation in Adriamycin nephropathy. Renal Failure, 27(5), 609-14. [More Information]
  • Kairaitis, L., Wang, Y., Gassmann, M., Tay, Y., Harris, D. (2005). HIF-1α expression follows microvascular loss in advanced murine adriamycin nephrosis. American Journal of Physiology: Renal Physiology (Print), 288(1), F198-F206. [More Information]
  • Zhang, G., Hu, M., Wang, Y., Osvath, S., Sedger, L., Alexander, S. (2005). IL-15 required for DST induced tolerance across a major class I mismatch. 6th American Transplant Congress, Oxford, UK: Blackwell Publishing Professionals.
  • Wang, Y., Mahajan, D., Tay, Y., Bao, B., Spicer, T., Kairaitis, L., Rangan, G., Harris, D. (2005). Partial depletion of macrophages by ED7 reduces renal injury in Adriamycin nephropathy. Nephrology, 10(5), 470-7. [More Information]
  • Zheng, G., Wang, Y., Mahajan, D., Qin, X., Wang, Y., Wang, Y., Alexander, S., Harris, D. (2005). The role of tubulointerstitial inflammation. Kidney International, 67(S94), S96-S100. [More Information]

2004

  • Wang, Y., Tay, Y., Harris, D. (2004). Proximal Tubule Cells Stimulated By Lipopolysaccharide Inhibit Macrophage Activation. Kidney International, 66(2), 655-62.
  • Sadlier, D., Connolly, S., Kieran, N., Roxburgh, S., Brazil, D., Kairaitis, L., Wang, Y., Harris, D., Doran, P., Brady, H. (2004). Sequential Extracellular Matrix-Focused And Baited-Global Cluster Analysis Of Serial Transcriptomic Profiles Identifies Candidate Modulators Of Renal Tubulointerstitial Fibrosis In Murine Adriamycin-Induced Nephropathy. Journal of Biological Chemistry, 279(28), 29670-80.

2003

  • Kairaitis, L., Wang, Y., Zheng, L., Tay, Y., Wang, Y., Harris, D. (2003). Blockade of CD40-CD40 ligand protects against renal injury in chronic proteinuric renal disease. Kidney International, 64(4), 1265-1272.

2002

  • Wang, Y., Harris, D., Rangan, G. (2002). Dietary Quercetin Augments activator Protein-1 and Does Not Reduce Nuclear Factor-KB in the Renal Cortex of Rats with Established Chronic Glomerular Disease. Nephron Journals, 90(3), 313-319.
  • Wang, Y., Yi, S., Tay, Y., Feng, X., Kairaitis, L., Harris, D. (2002). Transfection of tubule cells with Fas ligand causes leukocyte apoptosis. Kidney International, 61(4), 1303-1311.

To update your profile click here. For support on your academic profile contact .