Dr Joy Dai-Keller

Telephone (02) 8627 7707

Map

Biographical details

I am a postdoctoral research fellow in the School of Pharmacy, Faculty of Medicine and Health, based at the Charles Perkins Centre (CPC). As a believer of “food as (preventive) medicine,” my expertise is in nutritional epidemiology, primarily focused on the impact of nutrition in the prevention of chronic diseases across different ethnic populations around the world. My current work is to use systematic approaches to identify potential biases at all stages in nutrition research and to examine how the basis of scientific evidence used affects the development of dietary guidelines globally.

My passion in nutrition research is to identify targets for interventions to improve dietary quality and to provide solutions to improve research credibility to make dietary guidelines more robust.

Before joining the CPC, I was a T32 postdoctoral fellow at Boston University School of Medicine, studying the impacts of dietary factors (dietary fiber in particular) and other lifestyle factors on osteoporosis and osteoarthritis in several U.S. cohorts.

I received a Ph.D. in Epidemiology from the School of Public Health at National University of Singapore. My doctorate dissertation focused on how dietary patterns, foods, nutrients, body weight and bone turnover biomarkers affected osteoporotic hip fractures in a cohort of 63,000 Chinese people in Singapore. I also hold an M.S. in Food Science from Louisiana State University and an M.A. in Nutritional Science from The University of Texas at Austin. My work prior to my PhD studied the mechanistic effects of functional foods in obesity and breast cancer in molecular and animal models.

Research interests

My epidemiological research interest includes determining the roles of diet and other lifestyle factors in obesity, osteoporosis, osteoarthritis, and other aging health problems. My recent work looks at causal pathways to assess intermediators to inform prevention strategies in disease outcomes. As diet, physical activity and sleep contribute to shaping obesity, I am also interested in identifying factors that influence eating and other lifestyle behaviors, particularly the bidirectional relationships with human microbiome in chronic diseases.

I have on-going collaboration with epidemiologists at Boston University and Harvard University. I hope to expand collaboration in Australia and in the broader Asia-Pacific Region.

As a member of the Bias in Research node at the CPC, I use systematic review methods to identify hidden or understudied factors that affect the dissemination of results and conclusions in nutrition literature. One area is to evaluate the consistency in recommended intakes of specific dietary components. By mapping the links between funders and research processes, I hope to understand how the relationships among stakeholders impact disclosing conflicts of interest in nutrition studies.

Associations

Cochrane Nutrition 2018-present

American College of Arthritis 2016-present

Boston Nutrition Obesity Research Center 2015-present

American Society of Nutrition 2013-present

American Society of Bone and Mineral Research 2013- present

International Osteoporosis Foundation 2012-present

Awards and honours

Ruth L. Kirschstein Post-Doctoral National Research Service Award National Institute of Health (T32 fellowship) (2015-2018)

Travel Award sponsored by Boston Nutrition Obesity Research Center (BNORC) (2018)

Travel award sponsored by the Professional Development and Postdoctoral Affairs at Boston University (2017)

Travel award sponsored by the North America Chinese Society for Nutrition and America Society for Nutrition (2017)

Second place Laboratory Clinical Research Award in the Evans Department of Medicine Research Days Poster Session 2016 Boston University School of Medicine (Boston, MA, 2016)

Finalist (top 10% highly rated abstracts) - American Society of Nutrition in the ‘Emerging Leaders in Nutrition Science Poster Competition’Experimental Biology 2015 (Boston, MA, 2015)

Young Investigator Award (top 5% highly rated abstracts) by the 4th International Osteoporosis Foundation - Asia-Pacific Regional Conference 2014 (Taiwan, 2014)

Finalist for the ASBMR Phoebe Leboy Professional Development Award - American Society of Bone and Mineral Research annual meeting 2013 (Baltimore, MD, 2013)

Best Poster Award (top 2% highly rated abstracts) by International Life Sciences Institute Southeast Asia Region 2013 (Singapore, 2013)

Young Investigator Award (top 5% highly rated abstracts) by the 3rd International Osteoporosis Foundation - Asia-Pacific Regional Conference 2012 (Malaysia, 2012)

In the media

High-Fiber Diet Tied to Less Knee Arthritis (May 24, 2017)

https://www.nytimes.com/2017/05/24/well/eat/high-fiber-diet-tied-to-less-knee-arthritis.html

Want to avoid knee arthritis? Eat more fiber (May 23, 2017)

http://www.newsweek.com/arthritis-diet-fiber-knee-pain-prevent-614434

Older adults might be able to stave off arthritis knee pain with fiber (May 27, 2017)

https://www.reuters.com/article/us-health-arthritis-fiber-idUSKBN18M1VQ

Plant-based diet lowers risk of hip fracture (May 6, 2014)

https://www.todayonline.com/singapore/plant-based-diet-lowers-risk-hip-fracture-study

Studyfindsweightlossof10% ormoreinseniorssignificantly raiseshipfracturerisk (November15, 2014)

http://www.iofbonehealth.org/news/study-finds-weight-loss-10-or-more-seniors-significantly raises-hip-fracture-risk

Selected publications

Download citations: PDF RTF Endnote

Journals

  • Dai, Z., Zhang, Y., Lu, N., Felson, D., Kiel, D., Sahni, S. (2018). Association Between Dietary Fiber Intake and Bone Loss in the Framingham Offspring Study. Journal of Bone and Mineral Research, 33(2), 241-249. [More Information]
  • Dai, Z., Jin, A., Soh, A., Ang, L., Yuan, J., Koh, W. (2018). Coffee and tea drinking in relation to risk of hip fracture in the Singapore Chinese Health Study. Bone, 112, 51-57. [More Information]
  • Dai, Z., Zhang, Y. (2018). Does dietary fiber reduce the risk of rheumatoid arthritis? Fibers, 6(2), 1-4. [More Information]
  • Dai, Z., Lu, N., Niu, J., Felson, D., Zhang, Y. (2017). Dietary Fiber Intake in Relation to Knee Pain Trajectory. Arthritis Care and Research, 69(9), 1331-1339. [More Information]
  • Dai, Z., Niu, J., Zhang, Y., Jacques, P., Felson, D. (2017). Dietary intake of fibre and risk of knee osteoarthritis in two US prospective cohorts. Annals of the Rheumatic Diseases, 76(8), 1411-1419. [More Information]
  • Dai, Z., Felson, D., Zhang, Y. (2017). Reply. Arthritis Care and Research, 69(12), 1932-1933. [More Information]
  • Dai, Z., Wang, R., Ang, L., Yuan, J., Koh, W. (2016). Bone turnover biomarkers and risk of osteoporotic hip fracture in an Asian population. Bone, 83, 171-177. [More Information]
  • Dai, Z., Ang, L., Yuan, J., Koh, W. (2015). Association between change in body weight after midlife and risk of hip fracture�the Singapore Chinese Health Study. Osteoporosis International, 26(7), 1939-1947. [More Information]
  • Dai, Z., Koh, W. (2015). B-vitamins and bone health�a review of the current evidence. Nutrients, 7(5), 3322-3346. [More Information]
  • Dai, Z., Butler, L., van Dam, R., Ang, L., Yuan, J., Koh, W. (2014). Adherence to a vegetable-fruit-soy dietary pattern or the alternative healthy eating index is associated with lower hip fracture risk among Singapore Chinese. The Journal of Nutrition, 144(4), 511-518. [More Information]
  • Dai, Z., Wang, R., Ang, L., Low, Y., Yuan, J., Koh, W. (2014). Protective effects of dietary carotenoids on risk of hip fracture in men: The Singapore Chinese health study. Journal of Bone and Mineral Research, 29(2), 408-417. [More Information]
  • Dai, Z., Wang, R., Ang, L., Yuan, J., Koh, W. (2013). Dietary B vitamin intake and risk of hip fracture: The Singapore Chinese Health Study. Osteoporosis International, 24(7), 2049-2059. [More Information]
  • Nair, V., Dai, Z., Khan, M., Ciolino, H. (2011). Pomegranate extract induces cell cycle arrest and alters cellular phenotype of human pancreatic cancer cells. Anticancer Research, 31(9), 2699-2704.
  • Ciolino, H., Dai, Z., Nair, V. (2011). Retinol inhibits aromatase activity and expression in vitro. Journal of Nutritional Biochemistry, 22(6), 522-526. [More Information]

2018

  • Dai, Z., Zhang, Y., Lu, N., Felson, D., Kiel, D., Sahni, S. (2018). Association Between Dietary Fiber Intake and Bone Loss in the Framingham Offspring Study. Journal of Bone and Mineral Research, 33(2), 241-249. [More Information]
  • Dai, Z., Jin, A., Soh, A., Ang, L., Yuan, J., Koh, W. (2018). Coffee and tea drinking in relation to risk of hip fracture in the Singapore Chinese Health Study. Bone, 112, 51-57. [More Information]
  • Dai, Z., Zhang, Y. (2018). Does dietary fiber reduce the risk of rheumatoid arthritis? Fibers, 6(2), 1-4. [More Information]

2017

  • Dai, Z., Lu, N., Niu, J., Felson, D., Zhang, Y. (2017). Dietary Fiber Intake in Relation to Knee Pain Trajectory. Arthritis Care and Research, 69(9), 1331-1339. [More Information]
  • Dai, Z., Niu, J., Zhang, Y., Jacques, P., Felson, D. (2017). Dietary intake of fibre and risk of knee osteoarthritis in two US prospective cohorts. Annals of the Rheumatic Diseases, 76(8), 1411-1419. [More Information]
  • Dai, Z., Felson, D., Zhang, Y. (2017). Reply. Arthritis Care and Research, 69(12), 1932-1933. [More Information]

2016

  • Dai, Z., Wang, R., Ang, L., Yuan, J., Koh, W. (2016). Bone turnover biomarkers and risk of osteoporotic hip fracture in an Asian population. Bone, 83, 171-177. [More Information]

2015

  • Dai, Z., Ang, L., Yuan, J., Koh, W. (2015). Association between change in body weight after midlife and risk of hip fracture�the Singapore Chinese Health Study. Osteoporosis International, 26(7), 1939-1947. [More Information]
  • Dai, Z., Koh, W. (2015). B-vitamins and bone health�a review of the current evidence. Nutrients, 7(5), 3322-3346. [More Information]

2014

  • Dai, Z., Butler, L., van Dam, R., Ang, L., Yuan, J., Koh, W. (2014). Adherence to a vegetable-fruit-soy dietary pattern or the alternative healthy eating index is associated with lower hip fracture risk among Singapore Chinese. The Journal of Nutrition, 144(4), 511-518. [More Information]
  • Dai, Z., Wang, R., Ang, L., Low, Y., Yuan, J., Koh, W. (2014). Protective effects of dietary carotenoids on risk of hip fracture in men: The Singapore Chinese health study. Journal of Bone and Mineral Research, 29(2), 408-417. [More Information]

2013

  • Dai, Z., Wang, R., Ang, L., Yuan, J., Koh, W. (2013). Dietary B vitamin intake and risk of hip fracture: The Singapore Chinese Health Study. Osteoporosis International, 24(7), 2049-2059. [More Information]

2011

  • Nair, V., Dai, Z., Khan, M., Ciolino, H. (2011). Pomegranate extract induces cell cycle arrest and alters cellular phenotype of human pancreatic cancer cells. Anticancer Research, 31(9), 2699-2704.
  • Ciolino, H., Dai, Z., Nair, V. (2011). Retinol inhibits aromatase activity and expression in vitro. Journal of Nutritional Biochemistry, 22(6), 522-526. [More Information]

To update your profile click here. For support on your academic profile contact .