Publications list for Professor Chris Semsarian

2013 | 2012 | 2011 | 2010 | 2009 | 2008

2013

   
  • Gray, B., Yeates, L., Medi, C., Ingles, J., Semsarian, C. (2013), Homozygous mutation in the cardiac troponin I gene: Clinical heterogeneity in hypertrophic cardiomyopathy. International Journal of Cardiology. , 1530-1531. [Abstract]
  • Weintraub, R., Semsarian, C. (2013), Paediatric cardiomyopathy: getting to the heart of the matter. Lancet. 382(9908), 1866-1867. [Abstract]
  • Semsarian, C., Ingles, J. (2013), Expanding the genetic spectrum of hypertrophic cardiomyopathy: x marks the spot. Circulation. Cardiovascular Genetics. 6, 528-530. [Abstract]
  • Sweeting, J., Duflou, J., Semsarian, C. (2013), Postmortem analysis of cardiovascular deaths in schizophrenia: A 10-year review. Schizophrenia Research. 150(2-3), 398-403. [Abstract]
  • Ingles, J., Semsarian, C. (2013), The Australian Genetic Heart Disease Registry. International Journal of Cardiology. , e127-128. [Abstract]
  • Huang, M., Sivagurunathan, S., Ting, S., Jansson, P., Austin, C., Kelly, M., Semsarian, C., Zhang, D., Richardson, D. (2013), Molecular and Functional Alterations in a Mouse Cardiac Model of Friedreich Ataxia: Activation of the Integrated Stress Response, eIF2α Phosphorylation, and the Induction of Downstream Targets. The American Journal of Pathology. 183(3), 745-757. [Abstract]
  • Ingles, J., Sarina, T., Kasparian, N., Semsarian, C. (2013), Psychological wellbeing and posttraumatic stress associated with implantable cardioverter defibrillator therapy in young adults with genetic heart disease. International Journal of Cardiology. 168(4), 3779-3784. [Abstract]
  • Figtree, G., Bagnall, R., Abdulla, I., Buchholz, S., Galougahi, K., Yan, W., Tan, T., Neil, C., Horowitz, J., Semsarian, C., Ward, M. (2013), No association of G-protein-coupled receptor kinase 5 or β-adrenergic receptor polymorphisms with Takotsubo cardiomyopathy in a large Australian cohort. European Journal of Heart Failure. 15(7), 730-733. [Abstract]
  • Tsoutsman, T., Wang, X., Garchow, K., Riser, B., Twigg, S., Semsarian, C. (2013), CCN2 plays a key role in extracellular matrix gene expression in severe hypertrophic cardiomyopathy and heart failure. Journal of Molecular and Cellular Cardiology. 62, 164¿178. [Abstract]
  • Costa, M., Guo, G., Wolstein, O., Vale, M., Castro, M., Wang, L., Otway, R., Riek, P., Cochrane, N., Furtado, M., Semsarian, C., Weintraub, R., Yeoh, T., Hayward, C., Keogh, A., Macdonald, P., Feneley, M., Graham, R., Seidman, J., Seidman, C., Rosenthal, N., Fatkin, D., Harvey, R. (2013), Functional characterization of a novel mutation in NKX2-5 associated with congenital heart disease and adult-onset cardiomyopathy. Circulation. Cardiovascular Genetics. 6(3), 238-247. [Abstract]
  • Evans, A., Bagnall, R., Duflou, J., Semsarian, C. (2013), Postmortem review and genetic analysis in sudden infant death syndrome: an 11-year review. Human Pathology. 44(9), 1730-1736. [Abstract]
  • Ingles, J., Sarina, T., Yeates, L., Hunt, L., Macciocca, I., McCormack, L., Winship, I., McGaughran, J., Atherton, J., Semsarian, C. (2013), Clinical predictors of genetic testing outcomes in hypertrophic cardiomyopathy. Genetics in Medicine. 15(12), 972-977. [Abstract]
  • Maron, B., Spirito, P., Ackerman, M., Casey, S., Semsarian, C., Estes, N., Shannon, K., Ashley, E., Day, S., Pacileo, G., Formisano, F., Devoto, E., Anastasakis, A., Bos, J., Woo, A., Autore, C., Pass, R., Boriani, G., Garberich, R., Almquist, A., Russell, M., Boni, L., Berger, S., Maron, M., Link, M. (2013), Prevention of sudden cardiac death with implantable cardioverter-defibrillators in children and adolescents with hypertrophic cardiomyopathy. Journal of the American College of Cardiology. 61(14), 1527-1535. [Abstract]
  • Yeates, L., Hunt, L., Saleh, M., Semsarian, C., Ingles, J. (2013), Poor psychological wellbeing particularly in mothers following sudden cardiac death in the young. European Journal of Cardiovascular Nursing. 12(5), 484-491. [Abstract]
  • Gray, B., Ingles, J., Medi, C., Semsarian, C. (2013), Prolongation of the QTc Interval Predicts Appropriate Implantable Cardioverter-Defibrillator Therapies in Hypertrophic Cardiomyopathy. JACC. Heart Failure. 1(2), 149-155. [Abstract]
  • Redfern, J., Ingles, J., Neubeck, L., Johnston, S., Semsarian, C. (2013), Tweeting Our Way to Cardiovascular Health. Journal of the American College of Cardiology. 61(15), 1657-1658. [Abstract]
  • Offen, S., Celermajer, D., Semsarian, C., Puranik, R. (2013), The role of diastolic filling in preserving left ventricular stroke volume - An MRI study. International Journal of Cardiology. , 1596-1598. [Abstract]
  • Ingles, J., Yeates, L., Hunt, L., McGaughran, J., Scuffham, P., Atherton, J., Semsarian, C. (2013), Health status of cardiac genetic disease patients and their at-risk relatives. International Journal of Cardiology. 165(3), 448-453. [Abstract]
  • Padang, R., Bannon, P., Jeremy, R., Richmond, D., Semsarian, C., Vallely, M., Wilson, M., Yan, T. (2013), The genetic and molecular basis of bicuspid aortic valve associated thoracic aortopathy: a link to phenotype heterogeneity. Annals of Cardiothoracic Surgery. 2(1), 83-91. [Abstract]

2012

   
  • Padang, R., Bagnall, R., Semsarian, C. (2012), Genetic basis of familial valvular heart disease. Circulation: Cardiovascular Genetics. 5(5), 569-580. [Abstract]
  • Watts, G., Sullivan, D., van Bockxmeer, F., Poplawski, N., Hamilton-Craig, I., Clifton, P., O'Brien, R., Bishop, W., George, P., Semsarian, C., Tonkin, A. (2012), A New Model of Care for Familial Hypercholesterolaemia: What is the Role of Cardiology?. Heart, Lung & Circulation. 21(9), 543-550. [Abstract]
  • Maron, B., Maron, M., Semsarian, C. (2012), Genetics of hypertrophic cardiomyopathy after 20 years: clinical perspectives. Journal of the American College of Cardiology. 60(8), 705-715. [Abstract]
  • Gray, B., Das K, J., Semsarian, C. (2012), Consumption of energy drinks: A new provocation test for primary arrhythmogenic diseases?. International Journal of Cardiology. 159(1), 77-78. [Abstract]
  • Padang, R., Bagnall, R., Richmond, D., Bannon, P., Semsarian, C. (2012), Rare non-synonymous variations in the transcriptional activation domains of GATA5 in bicuspid aortic valve disease. Journal of Molecular and Cellular Cardiology. 53(2), 277-281. [Abstract]
  • Ingles, J., Yeates, L., O'Brien, L., McGaughran, J., Scuffham, P., Atherton, J., Semsarian, C. (2012), Genetic testing for inherited heart diseases: longitudinal impact on health-related quality of life. Genetics in Medicine. 14(9), 749-752. [Abstract]
  • Ingles, J., McGaughran, J., Scuffham, P., Atherton, J., Semsarian, C. (2012), A cost-effectiveness model of genetic testing for the evaluation of families with hypertrophic cardiomyopathy. Heart. 98(8), 625-630. [Abstract]
  • Maron, B., Semsarian, C. (2012), Prevention of sudden death for patients with cardiomyopathies another step forward. Journal of the American College of Cardiology. 59, 501-502. [Abstract]
  • Semsarian, C., Hamilton, R. (2012), Key Role of the Molecular Autopsy in Sudden Unexpected Death. Heart Rhythm. 9(1), 145-150. [Abstract]
  • Bagnall, R., Tsoutsman, T., Shephard, R., Ritchie, W., Semsarian, C. (2012), Global MicroRNA Profiling of the Mouse Ventricles during Development of Severe Hypertrophic Cardiomyopathy and Heart Failure. PLoS One. 7(9), e44744. [Abstract]
  • Maron, B., Maron, M., Semsarian, C. (2012), Double or compound sarcomere mutations in hypertrophic cardiomyopathy: a potential link to sudden death in the absence of conventional risk factors. Heart Rhythm. 9(1), 57-63. [Abstract]

2011

   
  • Ingles, J., Yeates, L., Semsarian, C. (2011), The Emerging Role of the Cardiac Genetic Counselor. Heart Rhythm. 8(12), 1958-1962. [Abstract]
  • Vohra, J., Skinner, J., Semsarian, C. (2011), Cardiac genetic investigation of young sudden unexplained death and resuscitated out of hospital cardiac arrest. Heart, Lung & Circulation. 20(12), 746-750. [Abstract]
  • Maron, B., Ahluwalia, A., Haas, T., Semsarian, C., Link, M., Estes, N. (2011), Global epidemiology and demographics of commotio cordis. Heart Rhythm. 8(12), 1969-1971. [Abstract]
  • Tu, E., Waterhouse, L., Duflou, J., Bagnall, R., Semsarian, C. (2011), Genetic analysis of hyperpolarisation-activated cyclic nucleotide-gated cation (HCN)channels in sudden unexpected in epilepsy (SUDEP) cases. Brain pathology (Zurich, Switzerland). 21(6), 692-8. [Abstract]
  • Ingles, J., Zodgekar, P., Yeates, L., Macciocca, I., Semsarian, C., Fatkin, D. (2011), Guidelines for genetic testing of inherited cardiac disorders. Heart, Lung & Circulation. 20(11), 681-687. [Abstract]
  • Gray, B., Semsarian, C., Sy, R., Jeremy, R. (2011), Left coronary artery fistula after septal myectomy in hypertrophic cardiomyopathy. Heart, Lung & Circulation. 20(11), 738. [Abstract]
  • Semsarian, C. (2011), Guidelines for the diagnosis and management of hypertrophic cardiomyopathy. Heart, Lung & Circulation. 20(11), 688-690. [Abstract]
  • Kelly, M., Bagnall, R., Peverill, R., Donelan, L., Corben, L., Delatycki, M., Semsarian, C. (2011), A polymorphic miR-155 binding site in AGTR1 is associated with cardiac hypertrophy in Friedreich ataxia. Journal of molecular and cellular cardiology. 51(5), 848-54. [Abstract]
  • Gray, B., Ingles, J., Semsarian, C. (2011), Natural history of genotype positive-phenotype negative patients with hypertrophic cardiomyopathy. International Journal of Cardiology. 152(2), 258-259. [Abstract]
  • Ackerman, M., Priori, S., Willems, S., Berul, C., Brugada, R., Calkins, H., Camm, A., Ellinor, P., Gollob, M., Hamilton, R., Hershberger, R., Judge, D., Le Marec, H., McKenna, W., Schulze-Bahr, E., Semsarian, C., Towbin, J., Watkins, H., Wilde, A., Wolpert, C., Zipes, D. (2011), HRS/EHRA expert consensus statement on the state of genetic testing for the channelopathies and cardiomyopathies this document was developed as a partnership between the Heart Rhythm Society (HRS) and the European Heart Rhythm Association (EHRA). Heart Rhythm. 8(8), 1308-1339. [Abstract]
  • Qian, L., Wythe, J., Liu, J., Cartry, J., Vogler, G., Mohapatra, B., Otway, R., Huang, Y., King, I., Maillet, M., Zheng, Y., Crawley, T., Taghli-Lamallem, O., Semsarian, C., Dunwoodie, S., Winlaw, D., Harvey, R., Fatkin, D., Towbin, J., Molkentin, J., Srivastava, D., Ocorr, K., Bruneau, B., Bodmer, R. (2011), Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species. The Journal of Cell Biology. 193(7), 1181-1196. [Abstract]
  • Bagnall, R., Ingles, J., Semsarian, C. (2011), Molecular diagnostics of cardiomyopathies: the future is here. Circulation. Cardiovascular Genetics. 4(2), 103-104. [Abstract]
  • Tu, E., Bagnall, R., Duflou, J., Semsarian, C. (2011), Post-Mortem Review and Genetic Analysis of Sudden Unexpected Death in Epilepsy (SUDEP) Cases. Brain pathology (Zurich, Switzerland). 21, 201-8. [Abstract]
  • Maron, B., Yeates, L., Semsarian, C. (2011), Clinical challenges of genotype positive (+)-phenotype negative (-) family members in hypertrophic cardiomyopathy. The American Journal of Cardiology. 107, 604-608. [Abstract]
  • Eshoo, S., Semsarian, C., Ross, D., Marwick, T., Thomas, L. (2011), Comparison of Left Atrial Phasic Function in Hypertrophic Cardiomyopathy Versus Systemic Hypertension Using Strain Rate Imaging. The American journal of cardiology. 107(2), 290-6. [Abstract]
  • Ng, D., Ng, I., Yeap, Y., Badrian, B., Tsoutsman, T., McMullen, J., Semsarian, C., Bogoyevitch, M. (2011), Opposing actions of extracellular signal-regulated kinase (ERK) and signal transducer and activator of transcription 3 (STAT3) in regulating microtubule stabilization during cardiac hypertrophy. The Journal of biological chemistry. 286(2), 1576-87. [Abstract]
  • Boase, N., Rychkov, G., Townley, S., Dinudom, A., Candi, E., Voss, A., Tsoutsman, T., Semsarian, C., Melino, G., Koentgen, F., Cook, D., Kumar, S. (2011), Respiratory distress and perinatal lethality in Nedd4-2-deficient mice. Nature Communications. 2, 287. [Abstract]

2010

   
  • Bagnall, R., Yeates, L., Semsarian, C. (2010), Analysis of the Z-disc genes PDLIM3 and MYPN in Patients with Hypertrophic Cardiomyopathy. International journal of cardiology. 145(3), 601-2. [Abstract]
  • Bagnall, R., Yeates, L., Semsarian, C. (2010), The role of large gene deletions and duplications in MYBPC3 and TNNT2 in patients with hypertrophic cardiomyopathy. International journal of cardiology. 145(0), 150-3. [Abstract]
  • Maron, B., Semsarian, C. (2010), Emergence of gene mutation carriers and the expanding disease spectrum of hypertrophic cardiomyopathy. European Heart Journal. 31, 1551-1553. [Abstract]
  • Lam, L., Tsoutsman, T., Arthur, J., Semsarian, C. (2010), Differential protein expression profiling of myocardial tissue in a mouse model of hypertrophic cardiomyopathy. Journal of molecular and cellular cardiology. 48(5), 1014-22. [Abstract]
  • Eshoo, S., Semsarian, C., Ross, D., Thomas, L. (2010), Left Atrial Phasic Volumes Are Modulated by the Type Rather Than the Extent of Left Ventricular Hypertrophy. Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography. 23(5), 538-44. [Abstract]
  • Girolami, F., Ho, C., Semsarian, C., Baldi, M., Will, M., Baldini, K., Torricelli, F., Yeates, L., Cecchi, F., Ackerman, M., Olivotto, I. (2010), Clinical features and outcome of hypertrophic cardiomyopathy associated with triple sarcomere protein gene mutations. Journal of the American College of Cardiology. 55(14), 1444-1453. [Abstract]
  • Chiu, C., Bagnall, R., Ingles, J., Yeates, L., Kennerson, M., Donald, J., Jormakka, M., Lind, J., Semsarian, C. (2010), Mutations in Alpha-Actinin-2 Cause Hypertrophic Cardiomyopathy A Genome-Wide Analysis. Journal of the American College of Cardiology. 55(11), 1127-1135. [Abstract]
  • Tu, E., Bagnall, R., Duflou, J., Lynch, M., Twigg, S., Semsarian, C. (2010), Post-mortem pathologic and genetic studies in "dead in bed syndrome" cases in type 1 diabetes mellitus. Human pathology. 41(3), 392-400. [Abstract]
  • Tu, E., Twigg, S., Semsarian, C. (2010), Sudden death in type 1 diabetes: The mystery of the 'dead in bed' syndrome. International journal of cardiology. 138(1), 91-3. [Abstract]

2009

   
  • Sherrid, M., Cotiga, D., Hart, D., Ehlert, F., Haas, T., Shen, W., Link, M., Estes, N., Epstein, A., Semsarian, C., Daubert, J., Winters, S., Giudici, M., Maron, B. (2009), Relation of 12-lead electrocardiogram patterns to implanted defibrillator-terminated ventricular tachyarrhythmias in hypertrophic cardiomyopathy. The American Journal of Cardiology. 104(12), 1722-1726. [Abstract]
  • Shephard, R., Semsarian, C. (2009), Role of animal models in HCM research. Journal of Cardiovascular Translational Research. 2(4), 471-482. [Abstract]
  • Wang, X., McLennan, S., Allen, T., Tsoutsman, T., Semsarian, C., Twigg, S. (2009), Adverse effects of high glucose and free fatty acid on cardiomyocytes are mediated by connective tissue growth factor. American journal of physiology. Cell physiology. 297(6), C1490-500. [Abstract]
  • Wilcox, I., Semsarian, C. (2009), Obstructive sleep apnea a respiratory syndrome with protean cardiovascular manifestations. Journal of the American College of Cardiology. 54, 1810-1812. [Abstract]
  • Maron, B., Semsarian, C., Shen, W., Link, M., Epstein, A., Estes, N., Almquist, A., Giudici, M., Haas, T., Hodges, J., Spirito, P. (2009), Circadian patterns in the occurrence of malignant ventricular tachyarrhythmias triggering defibrillator interventions in patients with hypertrophic cardiomyopathy. Heart Rhythm. 6(5), 599-602. [Abstract]
  • Kelly, M., Semsarian, C. (2009), Multiple mutations in genetic cardiovascular disease: a marker of disease severity?. Circulation: Cardiovascular Genetics. 2(2), 182-190. [Abstract]
  • Shephard, R., Semsarian, C. (2009), Advances in the prevention of sudden cardiac death in the young. Therapeutic Advances in Cardiovascular Disease. 3(2), 145-155. [Abstract]
  • Semsarian, C. (2009), Use of mouse models for the analysis of human disease. Current Protocols in Human Genetics. Supp 60, 15.2.1-15.2.10. [Abstract]

2008

   
  • Ingles, J., McGaughran, J., Vohra, J., Weintraub, R., Davis, A., Atherton, J., Semsarian, C. (2008), Establishment of an Australian National Genetic Heart Disease Registry. Heart, Lung & Circulation. 17(6), 463-467. [Abstract]
  • Skinner, J., Duflou, J., Semsarian, C. (2008), Reducing sudden death in young people in Australia and New Zealand: the TRAGADY initiative. The Medical journal of Australia. 189, 539-540. [Abstract]
  • Tsoutsman, T., Bagnall, R., Semsarian, C. (2008), Impact of multiple gene mutations in determining the severity of cardiomyopathy and heart failure. Clinical and experimental pharmacology & physiology. 35(11), 1349-57. [Abstract]
  • Vallely, M., Semsarian, C., Bannon, P. (2008), Management of the Ascending Aorta in Patients with Bicuspid Aortic Valve Disease. Heart, lung & circulation. 17(5), 357-63. [Abstract]
  • Lind, J., Chiu, C., Ingles, J., Yeates, L., Humphries, S., Heather, A., Semsarian, C. (2008), Sex hormone receptor gene variation associated with phenotype in male hypertrophic cardiomyopathy patients. Journal of Molecular and Cellular Cardiology. 45(2), 217-222. [Abstract]
  • Doolan, A., Langlois, N., Chiu, C., Ingles, J., Lind, J., Semsarian, C. (2008), Postmortem molecular analysis of KCNQ1 and SCN5A genes in sudden unexplained death in young Australians. International Journal of Cardiology. 127(1), 138-141. [Abstract]
  • Tu, E., Twigg, S., Duflou, J., Semsarian, C. (2008), Causes of death in young Australians with type 1 diabetes: a review of coronial postmortem examinations. The Medical Journal of Australia. 188(12), 699-702. [Abstract]
  • Tsoutsman, T., Kelly, M., Ng, D., Tan, J., Tu, E., Lam, L., Bogoyevitch, M., Seidman, C., Seidman, J., Semsarian, C. (2008), Severe heart failure and early mortality in a double-mutation mouse model of familial hypertrophic cardiomyopathy. Circulation. 117(14), 1820-1831. [Abstract]
  • Ingles, J., Lind, J., Phongsavan, P., Semsarian, C. (2008), Psychosocial impact of specialized cardiac genetic clinics for hypertrophic cardiomyopathy. Genetics in Medicine. 10(2), 117-120. [Abstract]