Publications list for Professor Des Richardson

2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006

2012

   
  • Lok, H., Suryo Rahmanto, Y., Hawkins, C., Kalinowski, D., Morrow, C., Townsend, A., Ponka, P., Richardson, D. (2012), Nitric oxide storage and transport in cells is mediated by glutathione-S-transferase P1-1 and Multidrug Resistant Protein 1 via Dinitrosyl iron complexes. The Journal of biological chemistry. 287(1), 607-18. [Abstract]
  • Yu, Y., Rahmanto, Y., Richardson, D. (2012), Bp44mT: An Orally-Active Iron Chelator of the Thiosemicarbazone Class with Potent Anti-Tumour Efficacy. British journal of pharmacology. 165(1), 148-66. [Abstract]

2011

   
  • Huang, M., Lane, D., Richardson, D. (2011), Mitochondrial Mayhem: The Mitochondrion as a Modulator of Iron Metabolism and Its Role in Disease. Antioxidants & redox signaling. 15(12), 3003-19. [Abstract]
  • Saletta, F., Kovacevic, Z., Richardson, D. (2011), Research Spotlight: Iron chelation: deciphering novel molecular targets for cancer therapy. The tip of the iceberg of a web of iron-regulated molecules. Future Medicinal Chemistry. 3(16), 1983-1986. [Abstract]
  • Saletta, F., Suryo Rahmanto, Y., Siafakas, A., Richardson, D. (2011), Cellular iron-depletion and the mechanisms involved in the iron-dependent regulation of the growth arrest and DNA damage family of genes. The Journal of biological chemistry. 286(41), 35396-406. [Abstract]
  • Stefani, C., Punnia-Moorthy, G., Lovejoy, D., Jansson, P., Kalinowski, D., Sharpe, P., Bernhardt, P., Richardson, D. (2011), Halogenated 2'-Benzoylpyridine Thiosemicarbazone (XBpT) Chelators with Potent and Selective Anti-Neoplastic Activity: Relationship to Intracellular Redox Activity. Journal of medicinal chemistry. 54(19), 6936-48. [Abstract]
  • Kovacevic, Z., Chikhani, S., Lovejoy, D., Richardson, D. (2011), Novel thiosemicarbazone iron chelators induce up-regulation and phosphorylation of the metastasis suppressor, NDRG1: A new strategy for the treatment of pancreatic cancer. Molecular pharmacology. 80(4), 598-609. [Abstract]
  • Lovejoy, D., Jansson, P., Brunk, U., Wong, J., Ponka, P., Richardson, D. (2011), Antitumor Activity of Metal-Chelating Compound Dp44mT Is Mediated by Formation of a Redox-Active Copper Complex That Accumulates in Lysosomes. Cancer research. 71(17), 5871-80. [Abstract]
  • Yu, Y., Suryo Rahmanto, Y., Hawkins, C., Richardson, D. (2011), The Potent and Novel Thiosemicarbazone Chelators, Dp44mT and Bp44mT, Affect Crucial Thiol Systems Required for Ribonucleotide Reductase Activity. Molecular pharmacology. 79(6), 921-31. [Abstract]
  • Kovacevic, Z., Sivagurunathan, S., Mangs, H., Chikhani, S., Zhang, D., Richardson, D. (2011), The metastasis suppressor, N-MYC downstream regulated gene 1 (NDRG1), UP-regulates P21 VIA P53-independent mechanisms. Carcinogenesis. 32(5), 732-40. [Abstract]
  • Yu, Y., Richardson, D. (2011), Cellular Iron Depletion Stimulates the JNK and p38 MAPK Signaling Transduction Pathways, Dissociation of ASK1-Thioredoxin, and Activation of ASK1. Journal of Biological Chemistry. 286(17), 15413-15427. [Abstract]
  • Kovacevic, Z., Yu, Y., Richardson, D. (2011), Chelators to the rescue: different horses for different courses!. Chemical Research in Toxicology. 24(3), 279-282. [Abstract]
  • Kovacevic, Z., Kalinowski, D., Lovejoy, D., Yu, Y., Rahmanto, Y., Sharpe, P., Bernhardt, P., Richardson, D. (2011), The Medicinal Chemistry of Novel Iron Chelators for the Treatment of Cancer. Current topics in medicinal chemistry. 11(5), 483-99. [Abstract]
  • Zhang, D., Richardson, D. (2011), Endoplasmic Reticulum Protein 29 (ERp29): The emerging role in cancer. The international journal of biochemistry & cell biology. 43(1), 33-6. [Abstract]
  • Bernhardt, P., Richardson, D. (2011), Metal chelation. Current Topics in Medicinal Chemistry. 11, 482. [Abstract]
  • Debebe, Z., Ammosova, T., Breuer, D., Lovejoy, D., Kalinowski, D., Karla, P., Kumar, K., Jerebtsova, M., Ray, P., Kashanchi, F., Gordeuk, V., Richardson, D., Nekhai, S. (2011), Iron chelators of the di-2-pyridylketone thiosemicarbazone and 2-benzoylpyridine thiosemicarbazone series inhibit HIV-1 transcription: identification of novel cellular targets--iron, cyclin-dependent kinase (CDK) 2, and CDK9. Molecular Pharmacology. 79(1), 185-196. [Abstract]
  • Sharpe, P., Richardson, D., Kalinowski, D., Bernhardt, P. (2011), Synthetic and natural products as iron chelators. Current Topics in Medicinal Chemistry. 11(5), 591-607. [Abstract]

2010

   
  • Saletta, F., Rahmanto, Y., Richardson, D. (2010), The Translational Regulator eIF3a: The Tricky eIF3 Subunit!. Biochimica et biophysica acta. 1806(2), 275-86. [Abstract]
  • Jansson, P., Hawkins, C., Lovejoy, D., Richardson, D. (2010), The iron complex of Dp44mT is redox-active and induces hydroxyl radical formation: An EPR study. Journal of inorganic biochemistry. 104(11), 1224-8. [Abstract]
  • Merlot, A., Pantarat, N., Lovejoy, D., Kalinowski, D., Richardson, D. (2010), Membrane Transport and Intracellular Sequestration of Novel Thiosemicarbazone Chelators for the Treatment of Cancer. Molecular pharmacology. 78(4), 675-84. [Abstract]
  • Jansson, P., Sharpe, P., Bernhardt, P., Richardson, D. (2010), Novel Thiosemicarbazones of the ApT and DpT Series and Their Copper Complexes: Identification of Pronounced Redox Activity and Characterization of Their Antitumor Activity. Journal of medicinal chemistry. 53(15), 5759-69. [Abstract]
  • Bendova, P., Mackova, E., Haskova, P., Vavrova, A., Jirkovsky, E., Sterba, M., Popelova, O., Kalinowski, D., Kovarikova, P., Vavrova, K., Richardson, D., Simunek, T. (2010), Comparison of Clinically Used and Experimental Iron Chelators for Protection against Oxidative Stress-Induced Cellular Injury. Chemical research in toxicology. 23(6), 1105-14. [Abstract]
  • Richardson, D., Lane, D., Becker, E., Huang, M., Whitnall, M., Rahmanto, Y., Sheftel, A., Ponka, P. (2010), Mitochondrial iron trafficking and the integration of iron metabolism between the mitochondrion and cytosol. Proceedings of the National Academy of Sciences of the United States of America. 107(24), 10775-82. [Abstract]
  • Kovacevic, Z., Kalinowski, D., Lovejoy, D., Quach, P., Wong, J., Richardson, D. (2010), Iron Chelators: Development of Novel Compounds with High and Selective Anti-Tumour Activity. Current Drug Delivery. 7(3), 194-207. [Abstract]
  • Stariat, J., Kovaríková, P., Klimes, J., Kalinowski, D., Richardson, D. (2010), Development of an LC-MS/MS method for analysis of interconvertible Z/E isomers of the novel anticancer agent, Bp4eT. Analytical and Bioanalytical Chemistry. 397(1), 161-171. [Abstract]
  • Richardson, D., Huang, M., Whitnall, M., Becker, E., Ponka, P., Suryo Rahmanto, Y. (2010), The ins and outs of mitochondrial iron-loading: the metabolic defect in Friedreich's ataxia. Journal of molecular medicine (Berlin, Germany). 88(4), 323-9. [Abstract]
  • Mrozek-Wilczkiewicz, A., Kalinowski, D., Musiol, R., Finster, J., Szurko, A., Serafin, K., Knas, M., Kamalapuram, S., Kovacevic, Z., Jampilek, J., Ratuszna, A., Rzeszowska-Wolny, J., Richardson, D., Polanski, J. (2010), Investigating the anti-proliferative activity of styrylazanaphthalenes and azanaphthalenediones. Bioorganic & medicinal chemistry. 18(7), 2664-2671. [Abstract]
  • Lane, D., Richardson, D. (2010), Frataxin, a molecule of mystery: trading stability for function in its iron-binding site. Biochemical Journal. 426(2), e1-e3. [Abstract]
  • Saletta, F., Suryo Rahmanto, Y., Noulsri, E., Richardson, D. (2010), Iron Chelator-Mediated Alterations in Gene Expression: Identification of Novel Iron-Regulated Molecules that are Molecular Targets of HIF-1{alpha} and p53. Molecular pharmacology. 77(0), 443-58. [Abstract]
  • Liu, J., Obando, D., Schipanski, L., Groebler, L., Witting, P., Kalinowski, D., Richardson, D., Codd, R. (2010), Conjugates of Desferrioxamine B (DFOB) with Derivatives of Adamantane or with Orally Available Chelators as Potential Agents for Treating Iron Overload. Journal of medicinal chemistry. 53(3), 1370-82. [Abstract]
  • Otevrel, J., Mandelova, Z., Pesko, M., Guo, J., Kralova, K., Sersen, F., Vejsova, M., Kalinowski, D., Kovacevic, Z., Coffey, A., Csollei, J., Richardson, D., Jampilek, J. (2010), Investigating the Spectrum of Biological Activity of Ring-Substituted Salicylanilides and Carbamoylphenylcarbamates. Molecules. 15(11), 8122-8142. [Abstract]
  • Kalinowski, D., Richardson, D. (2010), Cellular and Molecular Biology of Iron-Binding Proteins. In: Cellular and Molecular Biology of Metals. (pp.167-180).United States: Taylor and Francis.
  • Singleton, W., McInnes, K., Cater, M., Winnall, W., McKirdy, R., Yu, Y., Taylor, P., Ke, B., Richardson, D., Mercer, J., La Fontaine, S. (2010), Role of Glutaredoxin1 and Glutathione in Regulating the Activity of the Copper-transporting P-type ATPases, ATP7A and ATP7B. Journal of Biological Chemistry. 285, 27111-27121. [Abstract]
  • Brychtova, K., Opatrilova, R., Raich, I., Kalinowski, D., Dvorakova, L., Placek, L., Csollei, J., Richardson, D., Jampilek, J. (2010), Investigating the activity of 2-substituted alkyl-6-(2,5-dioxopyrrolidin-1-yl)hexanoates as skin penetration enhancers. Bioorganic & Medicinal Chemistry. 18(24), 8556-8565. [Abstract]
  • Miao, Q., Xu, D., Wang, Z., Xu, L., Wang, T., Wu, Y., Lovejoy, D., Kalinowski, D., Richardson, D., Nie, G., Zhao, Y. (2010), Amphiphilic hyper-branched co-polymer nanoparticles for the controlled delivery of anti-tumor agents. Biomaterials. 31(28), 7364-7375. [Abstract]

2009

   
  • Huang, M., Becker, E., Whitnall, M., Rahmanto, Y., Ponka, P., Richardson, D. (2009), Elucidation of the mechanism of mitochondrial iron loading in Friedreich's ataxia by analysis of a mouse mutant. Proceedings of the National Academy of Sciences of the United States of America. 106(38), 16381-16386. [Abstract]
  • Yu, Y., Kalinowski, D., Kovacevic, Z., Siafakas, A., Jansson, P., Stefani, C., Lovejoy, D., Sharpe, P., Bernhardt, P., Richardson, D. (2009), Thiosemicarbazones from the Old to New: Iron Chelators That Are More Than Just Ribonucleotide Reductase Inhibitors. Journal of medicinal chemistry. 52(17), 5271-94. [Abstract]
  • Kalinowski, D., Quach, P., Richardson, D. (2009), Thiosemicarbazones: the new wave in cancer treatment. Future Medicinal Chemistry. 1(6), 1143-1151. [Abstract]
  • Suryo, R., Richardson, D. (2009), Generation and characterization of transgenic mice hyper-expressing melanoma tumour antigen p97 (Melanotransferrin): No overt alteration in phenotype. Biochimica et biophysica acta. 1793(0), 1210-7. [Abstract]
  • Richardson, D., Kalinowski, D., Lau, S., Jansson, P., Lovejoy, D. (2009), Cancer cell iron metabolism and the development of potent iron chelators as anti-tumour agents. Biochimica et biophysica acta. 1790(0), 702-17. [Abstract]
  • Peslova, G., Petrak, J., Kuzelova, K., Hrdy, I., Halada, P., Kuchel, P., Soe-Lin, S., Ponka, P., Sutak, R., Becker, E., Huang, M., Suryo Rahmanto, Y., Richardson, D., Vyoral, D. (2009), Hepcidin, the hormone of iron metabolism, is bound specifically to {alpha}-2-macroglobulin in blood. Blood. 113(0), 6225-36. [Abstract]
  • Rosemary Siafakas, A., Richardson, D. (2009), Growth arrest and DNA damage-45 alpha (GADD45alpha). The international journal of biochemistry & cell biology. 41(0), 986-9. [Abstract]
  • Richardson, D., Kalinowski, D., Richardson, V., Sharpe, P., Lovejoy, D., Islam, M., Bernhardt, P. (2009), 2-Acetylpyridine Thiosemicarbazones are Potent Iron Chelators and Antiproliferative Agents: Redox Activity, Iron Complexation and Characterization of their Antitumor Activity. Journal of medicinal chemistry. 52(5), 1459-70. [Abstract]
  • Assinder, S., Dong, Q., Mangs, H., Richardson, D. (2009), Pharmacological Targeting of the Integrated AKT, PTEN and TGF-{beta} Pathways in Prostate Cancer. Molecular pharmacology. 75(3), 429-36. [Abstract]
  • Bernhardt, P., Sharpe, P., Islam, M., Lovejoy, D., Kalinowski, D., Richardson, D. (2009), Iron Chelators of the Dipyridylketone Thiosemicarbazone Class: Precomplexation and Transmetalation Effects on Anticancer Activity. Journal of medicinal chemistry. 52(2), 407-15. [Abstract]
  • Assinder, S., Dong, Q., Kovacevic, Z., Richardson, D. (2009), The TGF-beta, PI3K/Akt and PTEN pathways: established and proposed biochemical integration in prostate cancer. Biochemical Journal. 417(2), 411-421. [Abstract]
  • Stariat, J., Kovaríková, P., Klimes, J., Lovejoy, D., Kalinowski, D., Richardson, D. (2009), HPLC methods for determination of two novel thiosemicarbazone anti-cancer drugs (N4mT and Dp44mT) in plasma and their application to in vitro plasma stability of these agents. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 877(3), 316-322. [Abstract]
  • Bohlken, A., Cheung, B., Bell, J., Koach, J., Smith, S., Sekyere, E., Thomas, W., Norris, M., Haber, M., Lovejoy, D., Richardson, D., Marshall, G. (2009), ATP7A is a novel target of retinoic acid receptor beta2 in neuroblastoma cells. British Journal of Cancer. 100(1), 96-105. [Abstract]
  • Mladĕnka, P., Kalinowski, D., Haskova, P., Bobrovová, Z., Hrdina, R., Simůnek, T., Nachtigal, P., Semecký, V., Vávrová, J., Holeckova, M., Palicka, V., Mazurová, Y., Jansson, P., Richardson, D. (2009), The novel iron chelator, 2-pyridylcarboxaldehyde 2-thiophenecarboxyl hydrazone, reduces catecholamine-mediated myocardial toxicity. Chemical research in toxicology. 22(1), 208-217. [Abstract]
  • Noulsri, E., Richardson, D., Lerdwana, S., Fucharoen, S., Yamagishi, T., Kalinowski, D., Pattanapanyasat, K. (2009), Antitumor activity and mechanism of action of the iron chelator, Dp44mT, against leukemic cells. American Journal of Hematology. 84(3), 170-176. [Abstract]
  • Sheftel, A., Richardson, D., Prchal, J., Ponka, P. (2009), Mitochondrial Iron Metabolism and Sideroblastic Anemia. Acta Haematologica. 122(2-3), 120-133. [Abstract]
  • Lovejoy, D., Yu, Y., Richardson, D. (2009), Chelators as Anti-Cancer Drugs. In: Encyclopedia of Cancer. (pp.0).Germany: Springer.

2008

   
  • Lim, S., Raftery, M., Cai, H., Hsu, K., Yan, W., Hseih, H., Watts, R., Richardson, D., Thomas, S., Perry, M., Geczy, C. (2008), S-nitrosylated S100A8: novel anti-inflammatory properties. Journal of Immunology. 181(8), 5627-5636. [Abstract]
  • Kovacevic, Z., Fu, D., Richardson, D. (2008), The iron-regulated metastasis suppressor, Ndrg-1: Identification of novel molecular targets. Biochimica et biophysica acta. 1783(10), 1981-92. [Abstract]
  • Opletalova��, V., Kalinowski, D., Vejsova��, M., Kunes, J., Pour, M., Jampi��lek, J., Buchta, V., Richardson, D. (2008), Identification and Characterization of Thiosemicarbazones with Antifungal and Antitumor Effects: Cellular Iron Chelation Mediating Cytotoxic Activity. Chemical research in toxicology. 21(9), 1878-89. [Abstract]
  • Whitnall, M., Rahmanto, Y., Sutak, R., Xu, X., Becker, E., Mikhael, M., Ponka, P., Richardson, D. (2008), The MCK mouse heart model of Friedreich's ataxia: Alterations in iron-regulated proteins and cardiac hypertrophy are limited by iron chelation. Proceedings of the National Academy of Sciences of the United States of America. 105(28), 9757-62. [Abstract]
  • Lim, C., Kalinowski, D., Richardson, D. (2008), Protection Against Hydrogen Peroxide-Mediated Cytotoxicity in Friedreich's Ataxia Fibroblasts using Novel Iron Chelators of the PCIH Class. Molecular pharmacology. 74(1), 225-35. [Abstract]
  • Long, S., Jirků, M., Mach, J., Ginger, M., Sutak, R., Richardson, D., Tachezy, J., Lukeš, J. (2008), Ancestral roles of eukaryotic frataxin: mitochondrial frataxin function and heterologous expression of hydrogenosomal Trichomonas homologues in trypanosomes. Molecular microbiology. 69(1), 94-109. [Abstract]
  • Sutak, R., Lesuisse, E., Tachezy, J., Richardson, D. (2008), Crusade for iron: iron uptake in unicellular eukaryotes and its significance for virulence. Trends in microbiology. 16(6), 261-8. [Abstract]
  • Sutak, R., Xu, X., Whitnall, M., Kashem, M., Vyoral, D., Richardson, D. (2008), Proteomic analysis of hearts from frataxin knockout mice: marked rearrangement of energy metabolism, a response to cellular stress and altered expression of proteins involved in cell structure, motility and metabolism. Proteomics. 8(8), 1731-1741. [Abstract]
  • Richardson, D., Lok, H. (2008), The nitric oxide-iron interplay in mammalian cells: transport and storage of dinitrosyl iron complexes. Biochimica et Biophysica Acta. 1780(4), 638-651. [Abstract]
  • Xu, X., Sutak, R., Richardson, D. (2008), Iron Chelation by Clinically Relevant Anthracyclines: Alteration in Expression of Iron-Regulated Genes and Atypical Changes in Intracellular Iron Distribution and Trafficking. Molecular pharmacology. 73(3), 833-44. [Abstract]
  • Kalinowski, D., Sharpe, P., Bernhardt, P., Richardson, D. (2008), Structure-activity relationships of novel iron chelators for the treatment of iron overload disease: the methyl pyrazinylketone isonicotinoyl hydrazone series. Journal of Medicinal Chemistry. 51(2), 331-344. [Abstract]
  • Rahmanto, Y., Sekyere, E., Dunne, L., Richardson, D. (2008), The function of the membrane-bound transferrin homologue, melanotransferin (melanoma tumour antigen p97). In: Iron Metabolism and Disease. (pp.219-239).United States: Transworld Research.
  • Rahmanto, Y., Richardson, D. (2008), The Physiological and Pathophysiological Roles of Melanotransferrin. Germany: VDM Verlag.
  • Bernhardt, P., Wilson, G., Sharpe, P., Kalinowski, D., Richardson, D. (2008), Tuning the antiproliferative activity of biologically active iron chelators: characterization of the coordination chemistry and biological efficacy of 2-acetylpyridine and 2-benzoylpyridine hydrazone ligands. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry. 13(1), 107-19. [Abstract]
  • Farnaud, S., Amini, M., Rapisarda, C., Cammack, R., Bui, T., Drake, A., Evans, R., Rahmanto, Y., Richardson, D. (2008), Biochemical and spectroscopic studies of human melanotransferrin (MTf): electron-paramagnetic resonance evidence for a difference between the iron-binding site of MTf and other transferrins. The international journal of biochemistry & cell biology. 40(12), 2739-45. [Abstract]
  • Lovejoy, D., Yu, Y., Richardson, D. (2008), Chelators as anti-cancer drugs. In: Encyclopedia of Cancer. (pp.0).Germany: Springer.

2007

   
  • Kalinowski, D., Sharpe, P., Bernhardt, P., Richardson, D. (2007), Design, Synthesis, and Characterization of New Iron Chelators with Anti-Proliferative Activity: Structure-Activity Relationships of Novel Thiohydrazone Analogues. Journal of medicinal chemistry. 50(24), 6212-25. [Abstract]
  • Podeszwa, B., Niedbala, H., Polanski, J., Musiol, R., Tabak, D., Finster, J., Serafin, K., Milczarek, M., Wietrzyk, J., Boryczka, S., Mol, W., Jampilek, J., Dohnal, J., Kalinowski, D., Richardson, D. (2007), Investigating the antiproliferative activity of quinoline-5,8-diones and styrylquinolinecarboxylic acids on tumor cell lines. Bioorganic & medicinal chemistry letters. 17(22), 6138-6141. [Abstract]
  • Suryo Rahmanto, Y., Dunn, L., Richardson, D. (2007), Identification of Distinct Changes in Gene Expression after Modulation of Melanoma Tumor Antigen p97 (Melanotransferrin) in Multiple Models In Vitro and In Vivo. Carcinogenesis. 28(10), 2172-83. [Abstract]
  • Suryo Rahmanto, Y., Dunn, L., Richardson, D. (2007), The melanoma tumor antigen, melanotransferrin (p97): a 25-year hallmark - from iron metabolism to tumorigenesis. Oncogene. 26(42), 6113-24. [Abstract]
  • Yu, Y., Kovacevic, Z., Richardson, D. (2007), Tuning Cell Cycle Regulation With an Iron Key. Cell cycle (Georgetown, Tex.). 6(16), 1982-94. [Abstract]
  • Kalinowski, D., Yu, Y., Sharpe, P., Islam, M., Liao, Y., Lovejoy, D., Kumar, N., Bernhardt, P., Richardson, D. (2007), Design, Synthesis, and Characterization of Novel Iron Chelators: Structure-Activity Relationships of the 2-Benzoylpyridine Thiosemicarbazone Series and Their 3-Nitrobenzoyl Analogues as Potent Antitumor Agents. Journal of medicinal chemistry. 50(15), 3716-29. [Abstract]
  • Fu, D., Richardson, D. (2007), Iron chelation and regulation of the cell cycle: 2 mechanisms of posttranscriptional regulation of the universal cyclin-dependent kinase inhibitor p21CIP1/WAF1 by iron depletion. Blood. 110(2), 752-761. [Abstract]
  • Kalinowski, D., Richardson, D. (2007), Future of toxicology--iron chelators and differing modes of action and toxicity: the changing face of iron chelation therapy. Chemical research in toxicology. 20(5), 715-20. [Abstract]
  • Nurtjahja-Tjendraputra, E., Fu, D., Phang, J., Richardson, D. (2007), Iron Chelation regulates cyclin D1 expression via the proteasome: a link to iron deficiency-mediated growth suppression. Blood. 109, 4045-54. [Abstract]
  • Mrkvicková, Z., Kovaríková, P., Klimes, J., Kalinowski, D., Richardson, D. (2007), Development and validation of HPLC-DAD methods for the analysis of two novel iron chelators with potent anti-cancer activity. Journal of pharmaceutical and biomedical analysis. 43(4), 1343-1351. [Abstract]
  • Richardson, D., Suryo Rahmanto, Y. (2007), Differential regulation of the Menkes and Wilson disease copper transporters by hormones: an integrated model of metal transport in the placenta. The Biochemical journal. 402(2), e1-3. [Abstract]
  • Dunn, L., Rahmanto, Y., Richardson, D. (2007), Iron uptake and metabolism in the new millennium. Trends in cell biology. 17, 93-100. [Abstract]
  • Musiol, R., Jampilek, J., Kralova, K., Richardson, D., Kalinowski, D., Podeszwa, B., Finster, J., Niedbala, H., Palka, A., Polanski, J. (2007), Investigating biological activity spectrum for novel quinoline analogues. Bioorganic & medicinal chemistry. 15(3), 1280-1288. [Abstract]
  • Jerebtsova, M., Richardson, D., Nekhai, S., Gordeuk, V., Ray, P., Debebe, Z., Kurantsin-Mills, J., Ammosova, T., Charles, S., Niu, X. (2007), Iron chelators ICL670 and 311 inhibit HIV-1 transcription. VIROLOGY. 367(2), 324-333. [Abstract]
  • Sharpe, P., Richardson, D., Bernhardt, P., Chin, P. (2007), Hydrazone chelators for the treatment of iron overload disorders: iron coordination chemistry and biological activity. DALTON TRANSACTIONS. 30, 3232-3244. [Abstract]

2006

   
  • Kovacevic, Z., Richardson, D. (2006), The metastasis suppressor, Ndrg-1: a new ally in the fight against cancer. Carcinogenesis. 27, 2355-66. [Abstract]
  • Yu, Y., Wong, J., Lovejoy, D., Kalinowski, D., Richardson, D. (2006), Chelators at the cancer coalface: desferrioxamine to triapine and beyond. Clinical cancer research : an official journal of the American Association for Cancer Research. 12(23), 6876-83. [Abstract]
  • Richardson, D., Sharpe, P., Lovejoy, D., Senaratne, D., Kalinowski, D., Islam, M., Bernhardt, P. (2006), Dipyridyl Thiosemicarbazone Chelators with Potent and Selective Antitumor Activity Form Iron Complexes with Redox Activity. Journal of medicinal chemistry. 49(22), 6510-6521. [Abstract]
  • Dunn, L., Sekyere, E., Rahmanto, Y., Richardson, D. (2006), The function of melanotransferrin: a role in melanoma cell proliferation and tumorigenesis. Carcinogenesis. 27, 2157-69. [Abstract]
  • Whitnall, M., Howard, J., Ponka, P., Richardson, D. (2006), A class of iron chelators with a wide spectrum of potent antitumor activity that overcomes resistance to chemotherapeutics. Proceedings of the National Academy of Sciences of the United States of America. 103, 14901-6. [Abstract]
  • Richardson, D., Lovejoy, D. (2006), "Iron mining" if to inhibit tumor growth. Blood. 108(7), 2140-2140. [Abstract]
  • Whitnall, M., Richardson, D. (2006), Iron: a new target for pharmacological intervention in neurodegenerative diseases. Seminars in pediatric neurology. 13(3), 186-97. [Abstract]
  • Watts, R., Hawkins, C., Ponka, P., Richardson, D. (2006), Nitrogen monoxide (NO)-mediated iron release from cells is linked to NO-induced glutathione efflux via multidrug resistance-associated protein 1. Proceedings of the National Academy of Sciences of the United States of America. 103(20), 7670-7675. [Abstract]
  • Sekyere, E., Dunn, L., Rahmanto, Y., Richardson, D. (2006), Role of melanotransferrin in iron metabolism: studies using targeted gene disruption in vivo. Blood. 107(7), 2599-2601. [Abstract]
  • Sekyere, E., Dunn, L., Suryo Rahmanto, Y., Richardson, D. (2006), Role of melanotransferrin in iron metabolism: studies using targeted gene disruption in-vivo. Blood. 107(7), 2599-601. [Abstract]
  • Davies, N., Rahmanto, Y., Chitambar, C., Richardson, D. (2006), Resistance to the antineoplastic agent gallium nitrate results in marked alterations in intracellular iron and gallium trafficking: identification of novel intermediates. The Journal of pharmacology and experimental therapeutics. 317(1), 153-62. [Abstract]
  • Rahmanto, Y., Sekyere, E., Dunne, L., Richardson, D. (2006), Identification of melanotransferin (p97) associated genes using in vitro and in vivo models. Free Radical Research. 40, S55.
  • Sekyere, E., Dunne, L., Rahmanto, Y., Richardson, D. (2006), Role of melanotransferin in iron metabolism: studies using targeted gene disruption in vivo. Blood. 107, 2599-2601.
  • Lovejoy, D., Kalinowski, D., Bernhardt, P., Richardson, D. (2006), PCTH: a novel orally active chelator for the treatment of iron overload disease. Hemoglobin. 30(1), 93-104. [Abstract]