2012

• Young, M., Little, D., Kim, H. (2012), Evidence for using bisphosphonate to treat Legg-Calvé-Perthes disease. Clinical Orthopaedics and Related Research. 470(9), 2462-2475. [Abstract]
• McDonald, M., Morse, A., Mikulec, K., Peacock, L., Yu, N., Baldock, P., Birke, O., Liu, M., Ke, H., Little, D. (2012), Inhibition of sclerostin by systemic treatment with sclerostin antibody enhances healing of proximal tibial defects in ovariectomized rats. Journal of Orthopaedic Research. 30(10), 1541-1548. [Abstract]
• Gray, K., Pacey, V., Gibbons, P., Little, D., Frost, C., Burns, J. (2012), Interventions for congenital talipes equinovarus (clubfoot). Cochrane Database of Systematic Reviews. 4, CD008602. [Abstract]
• Yu, N., Schindeler, A., Tagil, M., Ruys, A., Little, D. (2012), Use of BMPs and bisphosphonates to improve bone fracture healing. Frontiers in Bioscience. 4, 2647-2653. [Abstract]
• Cairns, D., Liu, R., Sen, M., Canner, J., Schindeler, A., Little, D., Zeng, L. (2012), Interplay of Nkx3.2, Sox9 and Pax3 regulates chondrogenic differentiation of muscle progenitor cells. PLoS one. 7(7), e39642. [Abstract]

2011

• Sullivan, K., El-Hoss, J., Little, D., Schindeler, A. (2011), JNK inhibitors increase osteogenesis in Nf1-deficient cells. Bone. 49(6), 1311-6. [Abstract]
• Simm, P., Johannesen, J., Briody, J., McQuade, M., Hsu, B., Bridge, C., Little, D., Cowell, C., Munns, C. (2011), Zoledronic acid improves bone mineral density, reduces bone turnover and improves skeletal architecture over 2years of treatment in children with secondary osteoporosis. Bone. 49(5), 939-943. [Abstract]
• Yang, N., Schindeler, A., McDonald, M., Seto, J., Houweling, P., Lek, M., Hogarth, M., Morse, A., Raftery, J., Balasuriya, D., Macarthur, D., Berman, Y., Quinlan, K., Eisman, J., Nguyen, T., Center, J., Prince, R., Wilson, S., Zhu, K., Little, D., North, K. (2011), α-Actinin-3 deficiency is associated with reduced bone mass in human and mouse. Bone. 49(4), 790-798. [Abstract]
• El-Hoss, J., Sullivan, K., Cheng, T., Yu, N., Bobyn, J., Peacock, L., Mikulec, K., Baldock, P., Alexander, I., Schindeler, A., Little, D. (2011), A murine model of neurofibromatosis type 1 tibial pseudarthrosis featuring proliferative fibrous tissue and osteoclast-like cells. Journal of Bone and Mineral Research. 27(1), 68-78. [Abstract]
• Little, D., Kim, H. (2011), Potential for bisphosphonate treatment in legg-calve-perthes disease. Journal of Pediatric Orthopedics. 31(2 Suppl), S182-S188. [Abstract]
• Schindeler, A., Birke, O., Yu, N., Morse, A., Ruys, A., Baldock, P., Little, D. (2011), Distal tibial fracture repair in a neurofibromatosis type 1-deficient mouse treated with recombinant bone morphogenetic protein and a bisphosphonate. The Journal of Bone and Joint Surgery. British Volume. 93(8), 1134-1139. [Abstract]
• Little, D., Kim, H. (2011), Future biologic treatments for perthes disease. Orthopedic Clinics of North America. 42(3), 423-427. [Abstract]
• Wilkinson, J., Little, D. (2011), Bisphosphonates in orthopedic applications. Bone. 49(1), 95-102. [Abstract]
• Birke, O., Davies, N., Latimer, M., Little, D., Bellemore, M. (2011), Experience With the Fassier-Duval Telescopic Rod: First 24 Consecutive Cases With a Minimum of 1-Year Follow-up. Journal of Pediatric Orthopedics. 31(4), 458-464. [Abstract]
• Birke, O., Mitchell, P., Onikul, E., Little, D. (2011), The effect of hip position upon the location of the sciatic nerve: an MRI Study. Journal of Pediatric Orthopedics. 31(2), 165-169. [Abstract]
• El-Hoss, J., Micallef, A., Fairfull-Smith, K., Bottle, S., Little, D., Schindeler, A. (2011), Assessment of Tumor Prevention in Type 1 Neurofibromatosis using a Nitroxide Compound. Free Radicals and Antioxidants. 1(3), 13-18.
• Liu, R., Birke, O., Morse, A., Peacock, L., Mikulec, K., Little, D., Schindeler, A. (2011), Myogenic progenitors contribute to open but not closed fracture repair. BMC Musculoskeletal Disorders. 12, 288. [Abstract]

2010

• McDonald, M., Morse, A., Peacock, L., Mikulec, K., Schindeler, A., Little, D. (2010), Characterization of the bone phenotype and fracture repair in osteopetrotic Incisors absent rats. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. (5). [Abstract]
• Yu, N., Schindeler, A., Little, D., Ruys, A. (2010), Biodegradable poly(alpha-hydroxy acid) polymer scaffolds for bone tissue engineering. Journal of Biomedical Materials Research. Part B: Applied Biomaterials. 93(1), 285-295. [Abstract]
• Zreiqat, H., Ramaswamy, Y., Wu, C., Paschalidis, A., Lu, Z., James, B., Birke, O., McDonald, M., Little, D., Dunstan, C. (2010), The incorporation of strontium and zinc into a calcium-silicon ceramic for bone tissue engineering. Biomaterials. 31(12), 3175-3184. [Abstract]
• Tägil, M., McDonald, M., Morse, A., Peacock, L., Mikulec, K., Amanat, N., Godfrey, C., Little, D. (2010), Intermittent PTH (1-34) Does Not Increase Union Rates in Open Rat Femoral Fractures and Exhibits Attenuated Anabolic Effects Compared to Closed Fractures. Bone. 46(3), 852-9. [Abstract]
• Liu, R., Schindeler, A., Little, D. (2010), The potential role of muscle in bone repair. Journal of Musculoskeletal and Neuronal Interactions. 10(1), 71-76. [Abstract]
• Ferri-de-Barros, F., Little, D., Bridge, C., Cummine, J., Cree, A. (2010), Atlantoaxial and Craniocervical Arthrodesis in Children A Tomographic Study Comparing Suitability of C2 Pedicles and C2 Laminae for Screw Fixation. Spine. 35(3), 291-293. [Abstract]
• Goldhahn, J., Little, D., Mitchell, P., Fazzalari, N., Reid, I., Aspenberg, P., Marsh, D. (2010), Evidence for anti-osteoporosis therapy in acute fracture situations-Recommendations of a multidisciplinary workshop of the International Society for Fracture Repair. Bone. 46(2), 267-271. [Abstract]
• Kumar, J., Ramachandran, M., Little, D., Zenios, M. (2010), Pelvic osteomyelitis in children. Journal of pediatric orthopaedics. Part B. 19(1), 38-41. [Abstract]
• Yu, N., Schindeler, A., Peacock, L., Mikulec, K., Baldock, P., Ruys, A., Little, D. (2010), In vivo local co-delivery of recombinant human bone morphogenetic protein-7 and pamidronate via poly-D, L-lactic acid. European Cells & Materials. 20, 431-442. [Abstract]
• Schindeler, A., Morse, A., Peacock, L., Mikulec, K., Yu, N., Liu, R., Kijumnuayporn, S., McDonald, M., Baldock, P., Ruys, A., Little, D. (2010), Rapid cell culture and pre-clinical screening of a transforming growth factor-beta (TGF-beta) inhibitor for orthopaedics. BMC Musculoskeletal Disorders. 11, 105. [Abstract]
• Gray, K., Pacey, V., Gibbons, P., Little, D., Burns, J. (2010), Interventions for congenital talipes equinovarus. Cochrane Database of Systematic Reviews. 7(CD008602), 1-9.
• Birke, O., Schindeler, A., Ramachandran, M., Cowell, C., Munns, C., Bellemore, M., Little, D. (2010), Preliminary experience with the combined use of recombinant bone morphogenetic protein and bisphosphonates in the treatment of congenital pseudarthrosis of the tibia. Journal of Children's Orthopaedics. 4(6), 507–517.

2009

• Johannesen, J., Briody, J., McQuade, M., Little, D., Cowell, C., Munns, C. (2009), Systemic effects of zoledronic acid in children with traumatic femoral head avascular necrosis and Legg-Calve-Perthes disease. Bone. 45(5), 898-902. [Abstract]
• Kakar, S., Little, D., Einhorn, T. (2009), Can we improve fixation and outcomes in the treatment of femoral neck fractures? The use of pharmaceuticals. Journal of Orthopaedic Trauma. 23(6), 413-421. [Abstract]
• Little, D. (2009), Humanising a Mouse Gene for Human Therapeutics - Lessons From Denosumab. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 24(0), 179-81. [Abstract]
• Baldock, P., Lee, N., Driessler, F., Lin, S., Allison, S., Stehrer, B., Lin, E., Zhang, L., Enriquez, R., Wong, I., McDonald, M., During, M., Pierroz, D., Slack, K., Shi, Y., Yulyaningsih, E., Aljanova, A., Little, D., Ferrari, S., Sainsbury, A., Eisman, J., Herzog, H. (2009), Neuropeptide Y Knockout Mice Reveal a Central Role of NPY in the Coordination of Bone Mass to Body Weight. PLoS One. 4(12), e8415. [Abstract]
• Schindeler, A., Liu, R., Little, D. (2009), The contribution of different cell lineages to bone repair: exploring a role for muscle stem cells. Differentiation. 77(1), 12-18. [Abstract]
• Elefteriou, F., Kolanczyk, M., Schindeler, A., Viskochil, D., Hock, J., Schorry, E., Crawford, A., Friedman, J., Little, D., Peltonen, J., Carey, J., Feldman, D., Yu, X., Armstrong, L., Birch, P., Kendler, D., Mundlos, S., Yang, F., Agiostratidou, G., Hunter-Schaedle, K., Stevenson, D. (2009), Skeletal Abnormalities in Neurofibromatosis Type 1: Approaches to Therapeutic Options. American Journal of Medical Genetics Part A. 149A(10), 2327-2338. [Abstract]
• Liu, R., Ginn, S., Lek, M., North, K., Alexander, I., Little, D., Schindeler, A. (2009), Myoblast sensitivity and fibroblast insensitivity to osteogenic conversion by BMP-2 correlates with the expression of Bmpr-1a. BMC musculoskeletal disorders. 10(0), 51. [Abstract]

2008

• Yu, N., Ruys, A., Zenios, M., Godfrey, C., McDonald, M., Kiely, P., Mikulec, K., Little, D., Schindeler, A. (2008), Bisphosphonate-laden acrylic bone cement: Mechanical properties, elution performance, and in vivo activity. Journal of biomedical materials research. Part B, Applied biomaterials. 87(2), 482-91. [Abstract]
• Schindeler, A., McDonald, M., Bokko, P., Little, D. (2008), Bone remodeling during fracture repair: The cellular picture. Seminars in cell & developmental biology. 19(5), 459-66. [Abstract]
• McDonald, M., Dulai, S., Godfrey, C., Amanat, N., Sztynda, T., Little, D. (2008), Bolus or weekly zoledronic acid administration does not delay endochondral fracture repair but weekly dosing enhances delays in hard callus remodeling. Bone. 43(4), 653-62. [Abstract]
• Amanata, N., He, L., Swain, M., Little, D. (2008), The effect of zoledronic acid on the intrinsic material properties of healing bone: an indentation study. Medical Engineering and Physics. 30(7), 843-847. [Abstract]
• Schindeler, A., Morse, A., Harry, L., Godfrey, C., Mikulec, K., McDonald, M., Gasser, J., Little, D. (2008), Models of tibial fracture healing in normal and Nf1-deficient mice. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 26(8), 1053-60. [Abstract]
• Chang, A., Hook, J., Lemckert, F., McDonald, M., Nguyen, M., Hardeman, E., Little, D., Gunning, P., Reddel, R. (2008), The murine stanniocalcin 2 gene is a negative regulator of postnatal growth. Endocrinology. 149(5), 2403-2410. [Abstract]
• Schindeler, A., Little, D. (2008), Recent insights into bone development, homeostasis, and repair in type 1 neurofibromatosis (NF1). Bone. 42(4), 616-622. [Abstract]
• Schindeler, A., Ramachandran, M., Godfrey, C., Morse, A., McDonald, M., Mikulec, K., Little, D. (2008), Modeling bone morphogenetic protein and bisphosphonate combination therapy in wild-type and Nf1 haploinsufficient mice. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 26(1), 65-74. [Abstract]

2007

• Nelson, D., Zenios, M., Ward, K., Ramachandran, M., Little, D. (2007), The deformity index as a predictor of final radiological outcome in Perthes' disease. The Journal of bone and joint surgery. British volume. 89(10), 1369-1374. [Abstract]
• Zenios, M., Ramachandran, M., Milne, B., Little, D., Smith, N. (2007), Intraoperative stability testing of lateral-entry pin fixation of pediatric supracondylar humeral fractures. Journal of pediatric orthopedics. 27(6), 695-702. [Abstract]
• Munns, C., Rajab, M., Hong, J., Briody, J., Högler, W., McQuade, M., Little, D., Cowell, C. (2007), Acute phase response and mineral status following low dose intravenous zoledronic acid in children. Bone. 41(3), 366-70. [Abstract]
• Schindeler, A., Little, D. (2007), Bisphosphonate action: Revelations and deceptions from in vitro studies. Journal of pharmaceutical sciences. 96(8), 1872-1878. [Abstract]
• Ramachandran, M., Ward, K., Brown, R., Munns, C., Cowell, C., Little, D. (2007), Intravenous bisphosphonate therapy for traumatic osteonecrosis of the femoral head in adolescents. The Journal of bone and joint surgery. American volume. 89(8), 1727-1734. [Abstract]
• Baldock, P., Allison, S., Lundberg, P., Lee, N., Slack, K., Lin, E., Enriquez, R., McDonald, M., Zhang, L., During, M., Little, D., Eisman, J., Gardiner, E., Yulyaningsih, E., Lin, S., Sainsbury, A., Herzog, H. (2007), Novel role of y1 receptors in the coordinated regulation of bone and energy homeostasis. The Journal of Biological Chemistry. 282(26), 19092-19102. [Abstract]
• Kiely, P., Ward, K., Bellemore C, M., Briody, J., Cowell, C., Little, D. (2007), Bisphosphonate rescue in distraction osteogenesis: a case series. Journal of pediatric orthopedics. 27(4), 467-471. [Abstract]
• Dulai, S., Briody, J., Schindeler, A., North, K., Cowell, C., Little, D. (2007), Decreased bone mineral density in neurofibromatosis type 1: results from a pediatric cohort. Journal of pediatric orthopedics. 27(4), 472-475. [Abstract]
• Amanat, N., McDonald, M., Godfrey, C., Bilston, L., Little, D. (2007), Optimal timing of a single dose of zoledronic acid to increase strength in rat fracture repair. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 22(6), 867-876. [Abstract]
• Little, D., Ramachandran, M., Schindeler, A. (2007), The anabolic and catabolic responses in bone repair. The Journal of bone and joint surgery. British volume. 89-B(4), 425-433. [Abstract]
• Bransford, R., Goergens, E., Briody, J., Amanat, N., Cree, A., Little, D. (2007), Effect of zoledronic acid in an L6-L7 rabbit spine fusion model. European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society. 16, 557-62. [Abstract]
• Kumar, V., Kumar, D., Howman-Giles, R., Little, D. (2007), Is (99m)Tc-labelled pamidronate a better agent than (99m)Tc-medronate for bone imaging?. Nuclear medicine communications. 28(2), 101-107. [Abstract]
• Zenios, M., Ramachandran, M., Axt, M., Gibbons, P., Peat, J., Little, D. (2007), Posterior sloping angle of the capital femoral physis: interobserver and intraobserver reliability testing and predictor of bilaterality. Journal of pediatric orthopedics. 27(7), 801-804. [Abstract]