Publications list for Professor David Le Couteur

2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008

2014

   
  • Fransen, M., Su, S., Harmer, A., Blyth, F., Naganathan, V., Sambrook, P., Le Couteur, D., Cumming, R. (2014), A longitudinal study of knee pain in older men: Concord Health and Ageing in Men Project. Age and Ageing. 43(2), 206-212. [Abstract]
  • Le Couteur, D., Wilder, S., de Cabo, R., Simpson, S. (2014), The Evolution of Research on Ageing and Nutrition. Journals of Gerontology. Series A: Biological Sciences & Medical Sciences. 69, 1-2. [Abstract]
  • Fairhall, N., Sherrington, C., Cameron, I., Blyth, F., Naganathan, V., Clemson, L., Le Couteur, D., Handelsman, D., Waite, L., Cumming, R. (2014), Predicting participation restriction in community-dwelling older men: the Concord Health and Ageing in Men Project. Age and Ageing. 43(1), 31-37. [Abstract]
  • Gnjidic, D., Le Couteur, D., Hilmer, S., Cumming, R., Blyth, F., Naganathan, V., Waite, L., Handelsman, D., Simon Bell, J. (2014), Sedative load and functional outcomes in community-dwelling older Australian men: the CHAMP study. Fundamental and Clinical Pharmacology. 28(1), 10-19. [Abstract]

2013

   
  • Bleicher, K., Cumming, R., Naganathan, V., Seibel, M., Blyth, F., Le Couteur, D., Handelsman, D., Creasey, H., Waite, L. (2013), Predictors of the rate of BMD loss in older men: findings from the CHAMP study. Osteoporosis International. 24(7), 1951-1963. [Abstract]
  • McMahon, A., Parry, S., Benson, V., Witting, P., Le Couteur, D. (2013), Beneficial effects of the synthetic antioxidant tert-butyl bisphenol on the hepatic microcirculation in a rat model of diabetes mellitus. Acta Diabetologica. 50(4), 645-649. [Abstract]
  • Ilomaki, J., Gnjidic, D., Hilmer, S., Le Couteur, D., Naganathan, V., Cumming, R., Waite, L., Seibel, M., Blyth, F., Handelsman, D., Bell, J. (2013), Psychotropic drug use and alcohol drinking in community-dwelling older Australian men: the CHAMP study. Drug and Alcohol Review. 32(2), 218-222. [Abstract]
  • Huang, X., Hancock, D., Gosby, A., McMahon, A., Solon, S., Le Couteur, D., Conigrave, A., Raubenheimer, D., Simpson, S. (2013), Effects of dietary protein to carbohydrate balance on energy intake, fat storage and heat production in mice. Obesity. 21(1), 85-92. [Abstract]
  • Gnjidic, D., Le Couteur, D., Hilmer, S. (2013), Discontinuation of statins in routine care settings. Annals of Internal Medicine. , 73-74. [Abstract]
  • Hirani, V., Naganathan, V., Cumming, R., Blyth, F., Le Couteur, D., Handelsman, D., Waite, L., Seibel, M. (2013), Associations Between Frailty and Serum 25-Hydroxyvitamin D and 1,25-Dihydroxyvitamin D Concentrations in Older Australian Men: The Concord Health and Ageing in Men Project. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. 68(9), 1112-1121. [Abstract]
  • Gnjidic, D., Hilmer, S., Le Couteur, D. (2013), Optimal cutoff of polypharmacy and outcomes - reply. Journal of Clinical Epidemiology. 66(4), 465-466. [Abstract]
  • Horan, M., Rumbley, J., Melvin, R., Le Couteur, D., Ballard, J. (2013), Quaternary protein modeling to predict the function of DNA variation found in human mitochondrial cytochrome c oxidase. Journal of Human Genetics. 58(3), 127-134. [Abstract]
  • Wilder, S., Le Couteur, D., Simpson, S. (2013), Diet mediates the relationship between longevity and reproduction in mammals. Age. 35(3), 921-927. [Abstract]
  • Cogger, V., Roessner, U., Warren, A., Fraser, R., Le Couteur, D. (2013), A Sieve-Raft Hypothesis for the regulation of endothelial fenestrations. Computational and Structural Biotechnology Journal. 8(11), e201308003.
  • Le Couteur, D., Doust, J., Creasey, H., Brayne, C. (2013), Political drive to screen for pre-dementia: not evidence based and ignores the harms of diagnosis. BMJ. 347, f5125. [Abstract]
  • Hirani, V., Cumming, R., Blyth, F., Naganathan, V., Le Couteur, D., Handelsman, D., Waite, L., Seibel, M. (2013), Vitamin D Status among older community dwelling men living in a sunny country and associations with lifestyle factors: the Concord Health and Ageing in Men Project, Sydney, Australia. The Journal of Nutrition, Health and Aging. 17(7), 587-593. [Abstract]
  • Cogger, V., Roessner, U., Warren, A., Fraser, R., Le Couteur, D. (2013), A Sieve-Raft Hypothesis for the regulation of endothelial fenestrations. Computational and Structural Biotechnology Journal. 8, e201308003. [Abstract]
  • Gnjidic, D., Le Couteur, D., Pearson, S., McLachlan, A., Viney, R., Hilmer, S., Blyth, F., Joshy, G., Banks, E. (2013), High risk prescribing in older adults: prevalence, clinical and economic implications and potential for intervention at the population level. BMC Public Health. 13, 115. [Abstract]
  • Gnjidic, D., Le Couteur, D., Blyth, F., Travison, T., Rogers, K., Naganathan, V., Cumming, R., Waite, L., Seibel, M., Handelsman, D., McLachlan, A., Hilmer, S. (2013), Statin use and clinical outcomes in older men: a prospective population-based study. BMJ Open. 3(3), 1-10. [Abstract]

2012

   
  • Sørensen, K., McCourt, P., Berg, T., Crossley, C., Le Couteur, D., Wake, K., Smedsrød, B. (2012), The scavenger endothelial cell: a new player in homeostasis and immunity. American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 303(12), R1217-R1230. [Abstract]
  • Hilmer, S., Gnjidic, D., Le Couteur, D. (2012), Thinking through the medication list - appropriate prescribing and deprescribing in robust and frail older patients. Australian Family Physician. 41(12), 924-928. [Abstract]
  • Mitchell, S., Huizer-Pajkos, A., Cogger, V., McLachlan, A., Le Couteur, D., Jones, B., de Cabo, R., Hilmer, S. (2012), The Influence of Old Age and Poloxamer-407 on the Hepatic Disposition of Diazepam in the Isolated Perfused Rat Liver. Pharmacology. 90(5-6), 233-241. [Abstract]
  • Gnjidic, D., Hilmer, S., Blyth, F., Naganathan, V., Waite, L., Seibel, M., McLachlan, A., Cumming, R., Handelsman, D., Le Couteur, D. (2012), Polypharmacy cutoff and outcomes: five or more medicines were used to identify community-dwelling older men at risk of different adverse outcomes. Journal of Clinical Epidemiology. 65(9), 989-995. [Abstract]
  • Le Couteur, D., Robinson, M., Leverton, A., Creasey, H., Waite, L., Atkins, K., McLachlan, A. (2012), Adherence, persistence and continuation with cholinesterase inhibitors in Alzheimer's disease. Australasian Journal on Ageing. 31(3), 164-169. [Abstract]
  • Le Couteur, D., Handelsman, D. (2012), DNA damage, NF-κB and accelerated aging. Asian Journal of Andrology. 14(6), 811¿812. [Abstract]
  • Gnjidic, D., Le Couteur, D., Hilmer, S. (2012), Off-Label Use of Medicines: Time for Action. Clinical Pharmacology and Therapeutics. 92(2), 157. [Abstract]
  • Baur, J., Ungvari, Z., Minor, R., Le Couteur, D., de Cabo, R. (2012), Are sirtuins viable targets for improving healthspan and lifespan?. Nature Reviews. Drug Discovery. 11(6), 443-461. [Abstract]
  • Gnjidic, D., Le Couteur, D., Kouladjian, L., Hilmer, S. (2012), Deprescribing trials: methods to reduce polypharmacy and the impact on prescribing and clinical outcomes. Clinics in Geriatric Medicine. 28(2), 237-253. [Abstract]
  • Litchfield, M., Cumming, R., Smith, D., Naganathan, V., Le Couteur, D., Waite, L., Blyth, F., Handelsman, D. (2012), Prostate-specific antigen levels in men aged 70 years and over: findings from the CHAMP study. Medical Journal of Australia. 196(6), 395-398. [Abstract]
  • Gnjidic, D., Le Couteur, D., Naganathan, V., Cumming, R., Creasey, H., Waite, L., Sharma, A., Blyth, F., Hilmer, S. (2012), Effects of drug burden index on cognitive function in older men. Journal of Clinical Psychopharmacology. 32(2), 273-277. [Abstract]
  • Fraser, R., Cogger, V., Dobbs, B., Jamieson, H., Warren, A., Hilmer, S., Le Couteur, D. (2012), The liver sieve and atherosclerosis. Pathology. 44(3), 181-186. [Abstract]
  • Gnjidic, D., Hilmer, S., Blyth, F., Naganathan, V., Cumming, R., Handelsman, D., McLachlan, A., Abernethy, D., Banks, E., Le Couteur, D. (2012), High-risk prescribing and incidence of frailty among older community-dwelling men. Clinical pharmacology and therapeutics. 91(3), 521-528. [Abstract]
  • Le Couteur, D., McLachlan, A., Quinn, R., Simpson, S., de Cabo, R. (2012), Aging Biology and Novel Targets for Drug Discovery. Journals of Gerontology. Series A: Biological Sciences & Medical Sciences. 67(2), 168-174. [Abstract]
  • Le Couteur, D., McLachlan, A., de Cabo, R. (2012), Aging, Drugs, and Drug Metabolism. Journals of Gerontology. Series A: Biological Sciences & Medical Sciences. 67(2), 137-139. [Abstract]
  • Svistounov, D., Zykova, S., Cogger, V., Warren, A., McMahon, A., Fraser, R., Le Couteur, D. (2012), Liver Sinusoidal Endothelial Cells and Regulation of Blood Lipoproteins. In: Dyslipidemia - From Prevention to Treatment. (pp.263-278).Croatia: InTech.
  • Gnjidic, D., Hilmer, S., Le Couteur, D. (2012), High-risk prescribing in older people: More harm than good?. Aging Health. 8, 325-327.
  • Svistounov, D., Warren, A., McNerney, G., Owen, D., Zencak, D., Zykova, S., Crane, H., Huser, T., Quinn, R., Smedsrød, B., Le Couteur, D., Cogger, V. (2012), The Relationship between Fenestrations, Sieve Plates and Rafts in Liver Sinusoidal Endothelial Cells. PLoS One. 7(9), e46134. [Abstract]
  • Gnjidic, D., Stanaway, F., Cumming, R., Waite, L., Blyth, F., Naganathan, V., Handelsman, D., Le Couteur, D. (2012), Mild Cognitive Impairment Predicts Institutionalization among Older Men: A Population-Based Cohort Study. PLoS One. 7(9), e46061. [Abstract]
  • Bell, J., Le Couteur, D., McLachlan, A., Chen, T., Moles, R., Basger, B., Hilmer, S. (2012), Improving medicine selection for older people - Do we need an Australian classification for inappropriate medicines use?. Australian Family Physician. 41(1-2), 9-10. [Abstract]

2011

   
  • Bleicher, K., Cumming, R., Naganathan, V., Travison, T., Sambrook, P., Blyth, F., Handelsman, D., Le Couteur, D., Waite, L., Creasey, H., Seibel, M. (2011), The role of fat and lean mass in bone loss in older men: Findings from the CHAMP study. Bone. 49(6), 1299-1305. [Abstract]
  • Everitt, A., Le Couteur, D., Kendig, H. (2011), The changing face of ageing research and practice in Australia over the last 50 years. Australasian Journal on Ageing. 30(4), 173-174. [Abstract]
  • Benseler, V., Warren, A., Vo, M., Holz, L., Tay, S., Le Couteur, D., Breen, E., Allison, A., van Rooijen, N., McGuffog, C., Schlitt, H., Bowen, D., McCaughan, G., Bertolino, P. (2011), Hepatocyte entry leads to degradation of autoreactive CD8 T cells. Proceedings of the National Academy of Sciences of the United States of America. 108(40), 16735-40. [Abstract]
  • Stanaway, F., Cumming, R., Naganathan, V., Blyth, F., Handelsman, D., Le Couteur, D., Waite, L., Creasey, H., Seibel, M., Sambrook, P. (2011), Ethnicity and falls in older men: low rate of falls in Italian-born men in Australia. Age and Ageing. 40(5), 595-601. [Abstract]
  • Bleicher, K., Cumming, R., Naganathan, V., Seibel, M., Sambrook, P., Blyth, F., Le Couteur, D., Handelsman, D., Creasey, H., Waite, L. (2011), Lifestyle factors, medications, and disease influence bone mineral density in older men: findings from the CHAMP study. Osteoporosis International. 22(9), 2421-2437. [Abstract]
  • Travison, T., Nguyen, A., Naganathan, V., Stanaway, F., Blyth, F., Cumming, R., Le Couteur, D., Sambrook, P., Handelsman, D. (2011), Changes in Reproductive Hormone Concentrations Predict the Prevalence and Progression of the Frailty Syndrome in Older Men: The Concord Health and Ageing in Men Project. Journal of Clinical Endocrinology and Metabolism. 96(8), 2464-2474. [Abstract]
  • Gnjidic, D., Le Couteur, D., Abernethy, D., Hilmer, S. (2011), Reducing drugs in older adults is more. Archives of Internal Medicine. 171(9), 868-869. [Abstract]
  • Nabipour, I., Cumming, R., Handelsman, D., Litchfield, M., Naganathan, V., Waite, L., Creasey, H., Janu, M., Le Couteur, D., Sambrook, P., Seibel, M. (2011), Socioeconomic status and bone health in community-dwelling older men: the CHAMP Study. Osteoporosis International. 22(5), 1343-1353. [Abstract]
  • Mitchell, S., Huizer-Pajkos, A., Cogger, V., McLachlan, A., Le Couteur, D., Jones, B., de Cabo, R., Hilmer, S. (2011), Age-related pseudocapillarization of the liver sinusoidal endothelium impairs the hepatic clearance of acetaminophen in rats. Journals of Gerontology. Series A: Biological Sciences & Medical Sciences. 66(4), 400-408. [Abstract]
  • McLachlan, A., Bath, S., Naganathan, V., Hilmer, S., Le Couteur, D., Gibson, S., Blyth, F. (2011), Clinical pharmacology of analgesic medicines in older people: impact of frailty and cognitive impairment. British Journal of Clinical Pharmacology. 71(3), 351-364. [Abstract]
  • Labbé, A., Garand, C., Cogger, V., Paquet, E., Desbiens, M., Le Couteur, D., Lebel, M. (2011), Resveratrol improves insulin resistance hyperglycemia and hepatosteatosis but not hypertriglyceridemia, inflammation, and life span in a mouse model for Werner syndrome. Journals of Gerontology. Series A: Biological Sciences & Medical Sciences. 66(3), 264-278. [Abstract]
  • Gnjidic, D., Le Couteur, D., Abernethy, D., Hilmer, S. (2011), Drug Burden Index and Beers Criteria: Impact on Functional Outcomes in Older People Living in Self-Care Retirement Villages. Journal of Clinical Pharmacology. 52(2), 258-265. [Abstract]
  • Le Couteur, D., Simpson, S. (2011), Adaptive Senectitude: The Prolongevity Effects of Aging. The journals of gerontology. Series A, Biological sciences and medical sciences. 66(2), 179-82. [Abstract]
  • Warren, A., Benseler, V., Cogger, V., Bertolino, P., Le Couteur, D. (2011), The impact of poloxamer 407 on the ultrastructure of the liver and evidence for clearance by extensive endothelial and kupffer cell endocytosis. Toxicologic pathology. 39(2), 390-7. [Abstract]
  • Blyth, F., Cumming, R., Nicholas, M., Creasey, H., Handelsman, D., Le Couteur, D., Naganathan, V., Sambrook, P., Seibel, M., Waite, L. (2011), Intrusive pain and worry about health in older men: The CHAMP study. Pain. 152(2), 447-52. [Abstract]
  • Le Couteur, D., Banks, E., Gnjidic, D., McLachlan, A. (2011), Deprescribing. Australian Prescriber. 34(6), 182–185.
  • Warren, A., Cogger, V., Fraser, R., Deleve, L., McCuskey, R., Le Couteur, D. (2011), The effects of old age on hepatic stellate cells. Current Gerontology and Geriatrics Research. 2011, 439835. [Abstract]
  • Stanaway, F., Blyth, F., Cumming, R., Naganathan, V., Handelsman, D., Waite, L., Sambrook, P., Creasey, H., Seibel, M., Le Couteur, D. (2011), Back pain in older male Italian-born immigrants in Australia: The importance of socioeconomic factors. European Journal of Pain. 15(1), 70-76. [Abstract]
  • Le Couteur, D., Benson, V., McMahon, A., Blyth, F., Handelsman, D., Seibel, M., Kennerson, M., Naganathan, V., Cumming, R., de Cabo, R. (2011), Determinants of Serum-Induced SIRT1 Expression in Older Men: The CHAMP Study. Journals of Gerontology. Series A: Biological Sciences & Medical Sciences. 66(1), 3-8. [Abstract]
  • Mitchell, S., Huizer-Pajkos, A., Cogger, V., McLachlan, A., Le Couteur, D., Hilmer, S. (2011), Poloxamer 407 increases the recovery of paracetamol in the isolated perfused rat liver. Journal of pharmaceutical sciences. 100(1), 334-40. [Abstract]
  • Stanaway, F., Gnjidic, D., Blyth, F., Le Couteur, D., Naganathan, V., Waite, L., Seibel, M., Handelsman, D., Sambrook, P., Cumming, R. (2011), How fast does the Grim Reaper walk? Receiver operating characteristics curve analysis in healthy men aged 70 and over. BMJ. 343, d7679. [Abstract]
  • McMahon, A., Hing, A., Cogger, V., Le Couteur, D. (2011), Animal models of early atherosclerosis: How to translate the data into clinical perspectives. In: Silent Vasculopathy in Childhood: Should Clinicians Care?. (pp.39-64).India: Transworld Research Network.
  • Le Couteur, D., Cogger, V., Dobbs, B., Fraser, R. (2011), Fenestrations and lipoproteins. Cardiovascular pathology : the official journal of the Society for Cardiovascular Pathology. , 191-3; author reply 193-4. [Abstract]

2010

   
  • Nabipour, I., Sambrook, P., Blyth, F., Janu, M., Waite, L., Naganathan, V., Handelsman, D., Le Couteur, D., Cumming, R., Seibel, M. (2010), Serum uric acid is associated with bone health in older men: A cross-sectional, population-based study. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. (5). [Abstract]
  • Gnjidic, D., Le Couteur, D., Abernethy, D., Hilmer, S. (2010), A Pilot Randomized Clinical Trial Utilizing the Drug Burden Index to Reduce Exposure to Anticholinergic and Sedative Medications in Older People (November). The Annals of pharmacotherapy. 44(11), 1725-32. [Abstract]
  • Hairi, N., Cumming, R., Naganathan, V., Handelsman, D., Le Couteur, D., Creasey, H., Waite, L., Seibel, M., Sambrook, P. (2010), Loss of Muscle Strength, Mass (Sarcopenia), and Quality (Specific Force) and Its Relationship with Functional Limitation and Physical Disability: The Concord Health and Ageing in Men Project. Journal of the American Geriatrics Society. 58(11), 2055-2062. [Abstract]
  • Bleicher, K., Naganathan, V., Cumming, R., Seibel, M., Sambrook, P., Blyth, F., Le Couteur, D., Handelsman, D., Waite, L., Creasey, H. (2010), Prevalence and treatment of osteoporosis in older Australian men: findings from the CHAMP study. The Medical Journal of Australia. 193(7), 387-391. [Abstract]
  • Cheluvappa, R., Denning, G., Lau, G., Grimm, M., Hilmer, S., Le Couteur, D. (2010), Pathogenesis of the hyperlipidemia of Gram-negative bacterial sepsis may involve pathomorphological changes in liver sinusoidal endothelial cells. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 14(10), e857-67. [Abstract]
  • Le Couteur, D., Lakatta, E. (2010), A Vascular Theory of Aging. The journals of gerontology. Series A, Biological sciences and medical sciences. 65(10), 1025-7. [Abstract]
  • Simon-Santamaria, J., Malovic, I., Warren, A., Oteiza, A., Le Couteur, D., Smedsrød, B., McCourt, P., Sørensen, K. (2010), Age-Related Changes in Scavenger Receptor-Mediated Endocytosis in Rat Liver Sinusoidal Endothelial Cells. The journals of gerontology. Series A, Biological sciences and medical sciences. 65(9), 951-60. [Abstract]
  • Cogger, V., McNerney, G., Nyunt, T., Deleve, L., McCourt, P., Smedsrød, B., Couteur, D., Huser, T. (2010), Three dimensional structured illumination microscopy of liver sinusoidal endothelial cell fenestrations. Journal of structural biology. 171(3), 382-8. [Abstract]
  • Pallardó, F., Lloret, A., Lebel, M., d'Ischia, M., Cogger, V., Le Couteur, D., Gadaleta, M., Castello, G., Pagano, G. (2010), Mitochondrial dysfunction in some oxidative stress-related genetic diseases: Ataxia-Telangiectasia, Down Syndrome, Fanconi Anaemia and Werner Syndrome. Biogerontology. 11(4), 401-419. [Abstract]
  • Le Couteur, D., Sinclair, D. (2010), A Blueprint for Developing Therapeutic Approaches That Increase Healthspan and Delay Death. The journals of gerontology. Series A, Biological sciences and medical sciences. 65(7), 693-4. [Abstract]
  • Le Couteur, D., Blyth, F., Creasey, H., Handelsman, D., Naganathan, V., Sambrook, P., Seibel, M., Waite, L., Cumming, R. (2010), The Association of Alanine Transaminase With Aging, Frailty, and Mortality. The journals of gerontology. Series A, Biological sciences and medical sciences. 65(7), 712-7. [Abstract]
  • Kwong, P., Cumming, R., Chan, L., Seibel, M., Naganathan, V., Creasey, H., Le Couteur, D., Waite, L., Sambrook, P., Handelsman, D. (2010), Urinary incontinence and quality of life among older community-dwelling Australian men: the CHAMP study. Age and Ageing. 39(3), 349-354. [Abstract]
  • O'Reilly, J., Cogger, V., Fraser, R., Le Couteur, D. (2010), The effect of feeding and fasting on fenestrations in the liver sinusoidal endothelial cell. Pathology. 42(3), 255-258. [Abstract]
  • Rochat, S., Cumming, R., Blyth, F., Creasey, H., Handelsman, D., Le Couteur, D., Naganathan, V., Sambrook, P., Seibel, M., Waite, L. (2010), Frailty and use of health and community services by community-dwelling older men: the Concord Health and Ageing in Men Project. Age and Ageing. 39(2), 228-233. [Abstract]
  • Sabaretnam, T., O'Reilly, J., Kritharides, L., Le Couteur, D. (2010), The effect of old age on apolipoprotein E and its receptors in rat liver. Age (Dordrecht, Netherlands). 32(1), 69-77. [Abstract]
  • Holz, L., Warren, A., Le Couteur, D., Bowen, D., Bertolino, P. (2010), CD8+ T cell tolerance following antigen recognition on hepatocytes. Journal of autoimmunity. 34(1), 15-22. [Abstract]
  • Sabaretnam, T., Kritharides, L., O'Reilly, J., Le Couteur, D. (2010), The effect of aging on the response of isolated hepatocytes to hydrogen peroxide and tert-butyl hydroperoxide. Toxicology in vitro : an international journal published in association with BIBRA. 24(1), 123-8. [Abstract]
  • Mitchell, S., Kirkpatrick, C., Le Couteur, D., Naganathan, V., Sambrook, P., Seibel, M., Blyth, F., Waite, L., Handelsman, D., Cumming, R., Hilmer, S. (2010), Estimation of lean body weight in older community-dwelling men. British Journal of Clinical Pharmacology. 69(2), 118-127. [Abstract]
  • Le Couteur, D. (2010), Red yeast rice for dyslipidemia in statin-intolerant patients. Annals of Internal Medicine. , 134-135. [Abstract]
  • Warren, A., Cogger, V., Arias, I., McCuskey, R., Le Couteur, D. (2010), Liver sinusoidal endothelial fenestrations in caveolin-1 knockout mice. Microcirculation. 17(1), 32-38. [Abstract]
  • O'Reilly, J., Cogger, V., Le Couteur, D. (2010), Old age is associated with ultrastructural changes in isolated rat liver sinusoidal endothelial cells. Journal of electron microscopy. 59(0), 65-9. [Abstract]
  • Le Couteur, D., Ford, G., McLachlan, A. (2010), Evidence, Ethics and Medication Management in Older People. Journal of Pharmacy Practice and Research. 40(2), 148-152.
  • Le Couteur, D., Kendig, H., Naganathan, V., McLachlan, A. (2010), The Ethics of Prescribing to Older People. In: Medication Management in Older Adults. (pp.29-42).United States: Springer Science + Business Media B.V..
  • Everitt, A., Heilbronn, L., Le Couteur, D. (2010), Food Intake, Life Style, Aging and Human Longevity. In: Calorie Restriction, Ageing and Longevity. (pp.15-42).Germany, United Stat: Springer Science + Business Media B.V..
  • Everitt, A., Brown-Borg, H., Le Couteur, D., Bartke, A. (2010), Food Restriction, Hormones, Genes and Aging. In: Calorie Restriction, Ageing and Longevity. (pp.217-232).Germany, United Stat: Springer Science + Business Media B.V..
  • Le Couteur, D., Sinclair, D., Cogger, V., McMahon, A., Warren, A., Everitt, A., Lebel, M., de Cabo, R. (2010), The Aging Liver and the Effects of Long Term Caloric Restriction. In: Calorie Restriction, Ageing and Longevity. (pp.191-216).Germany, United Stat: Springer Science + Business Media B.V..
  • McLachlan, A., Hilmer, S., Le Couteur, D. (2010), Dosing Errors: Age-Related Changes in Pharmacokinetics. In: Medication Management in Older Adults. (pp.127-125).United States: Springer Science + Business Media B.V..
  • Massip, L., Garand, C., Paquet, E., Cogger, V., O'Reilly, J., Tworek, L., Hatherell, A., Taylor, C., Thorin, E., Zahradka, P., Le Couteur, D., Lebel, M. (2010), Vitamin C restores healthy aging in a mouse model for Werner syndrome. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 24(1), 158-72. [Abstract]
  • Everitt, A., Heilbronn, L., Morris, B., Brown-Borg, H., Merry, B., Simpson, S., Varady, K., Masoro, E., Redman, L., Le Couteur, D. (2010), Conclusion: Human Calorie Restriction and Anti-Aging Therapy. In: Calorie Restriction, Ageing and Longevity. (pp.311-318).Germany, United Stat: Springer Science + Business Media B.V..

2009

   
  • Sabaretnam, T., Harris, M., Kockx, M., Witting, P., Le Couteur, D., Kritharides, L. (2009), The Effects Of Hydrogen Peroxide And Apolipoprotein E Isoforms On Apolipoprotein E Trafficking In Hepg2 Cells. Clinical and Experimental Pharmacology & Physiology. 36(12), e96-102. [Abstract]
  • Gnjidic, D., Cumming, R., Le Couteur, D., Handelsman, D., Naganathan, V., Abernethy, D., Hilmer, S. (2009), Drug Burden Index and physical function in older Australian men. British Journal of Clinical Pharmacology. 68(1), 97-105. [Abstract]
  • Hilmer, S., Seale, J., Le Couteur, D., Crampton, R., Liddle, C. (2009), Do medical courses adequately prepare interns for safe and effective prescribing in New South Wales public hospitals?. Internal medicine journal. 39(7), 428-34. [Abstract]
  • Cumming, R., Handelsman, D., Seibel, M., Creasey, H., Sambrook, P., Waite, L., Naganathan, V., Couteur, D., Litchfield, M. (2009), Cohort profile: The Concord Health and Ageing in Men Project (CHAMP). International journal of epidemiology. 38(0), 374-8. [Abstract]
  • McLachlan, A., Hilmer, S., Le Couteur, D. (2009), Variability in response to medicines in older people: phenotypic and genotypic factors. Clinical Pharmacology and Therapeutics. 85(4), 431-433. [Abstract]
  • Smedsrød, B., Le Couteur, D., Ikejima, K., Jaeschke, H., Kawada, N., Naito, M., Knolle, P., Nagy, L., Senoo, H., Vidal-Vanaclocha, F., Yamaguchi, N. (2009), Hepatic sinusoidal cells in health and disease: update from the 14th International Symposium. Liver International. 29(4), 490-501. [Abstract]
  • Le Couteur, D., Everitt, A., Lebel, M. (2009), The aging liver. Geriatrics & Ageing. 12, 319-322.
  • Cheluvappa, R., Denning, G., Lau, G., Grimm, M., Hilmer, S., Le Couteur, D. (2009), Pseudomonas aeruginosa and the hyperlipidaemia of sepsis. Pathology. 41(7), 615-621. [Abstract]

2008

   
  • Cheluvappa, R., Cogger, V., Kwun, S., O'Reilly, J., Le Couteur, D., Hilmer, S. (2008), Liver sinusoidal endothelial cells and acute non-oxidative hepatic injury induced by Pseudomonas aeruginosa pyocyanin. International Journal of Experimental Pathology. 89(6), 410-418. [Abstract]
  • Blyth, F., Rochat, S., Cumming, R., Creasey, H., Handelsman, D., Couteur, D., Naganathan, V., Sambrook, P., Seibel, M., Waite, L. (2008), Pain, frailty and comorbidity on older men: The CHAMP study. Pain. 140(0), 224-30. [Abstract]
  • Pearson, K., Baur, J., Lewis, K., Peshkin, L., Price, N., Labinskyy, N., Swindell, W., Kamara, D., Minor, R., Perez, E., Jamieson, H., Zhang, Y., Dunn, S., Sharma, K., Pleshko, N., Woollett, L., Csiszar, A., Ikeno, Y., Le Couteur, D., Elliott, P., Becker, K., Navas, P., Ingram, D., Wolf, N., Ungvari, Z., Sinclair, D., de Cabo, R. (2008), Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span. Cell metabolism. 8(2), 157-168. [Abstract]
  • Cogger, V., Arias, I., Warren, A., McMahon, A., Kiss, D., Avery, V., Le Couteur, D. (2008), The response of fenestrations, actin and caveolin-1 to vascular endothelial growth factor in SK Hep1 cells (a liver endothelial cell line). American journal of physiology. Gastrointestinal and liver physiology. 295, G137-G145. [Abstract]
  • Le Couteur, D., Warren, A., Cogger, V., Smedsrød, B., Sørensen, K., De Cabo, R., Fraser, R., McCuskey, R. (2008), Old age and the hepatic sinusoid. Anatomical Record. 291(6), 672-683. [Abstract]
  • Warren, A., Chaberek, S., Ostrowski, K., Cogger, V., Hilmer, S., McCuskey, R., Fraser, R., Le Couteur, D. (2008), Effects of old age on vascular complexity and dispersion of the hepatic sinusoidal network. Microcirculation. 15(3), 191-202. [Abstract]
  • Le Couteur, D., Kendig, H. (2008), Pharmaco-epistemology for the prescribing geriatrician. Australasian Journal on Ageing. 27(1), 3-7. [Abstract]
  • Cheluvappa, R., Shimmon, R., Dawson, M., Hilmer, S., Le Couteur, D. (2008), Reactions of Pseudomonas aeruginosa pyocyanin with reduced glutathione. Acta biochimica Polonica. 55(3), 571-80. [Abstract]
  • Martinez, I., Nedredal, G., Oie, C., Warren, A., Johansen, O., Le Couteur, D., Smedsrød, B. (2008), The influence of oxygen tension on the structure and function of isolated liver sinusoidal endothelial cells. Comparative Hepatology. 7(4), 0. [Abstract]
  • Iyer, S., Naganathan, V., McLachlan, A., Le Couteur, D. (2008), Medication Withdrawal Trials in People Aged 65 Years and Older : A Systematic Review. Drugs & Aging. 25(12), 1021-1031. [Abstract]