Publications list for Professor John Simes

2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008


  • Carter, H., Zannino, D., John Simes, R., Schofield, D., Howard, K., Zalcberg, J., Price, T., Tebbutt, N. (2014), The cost effectiveness of bevacizumab when added to capecitabine, with or without mitomycin-C, in first line treatment of metastatic colorectal cancer: Results from the Australasian phase III MAX study. European Journal of Cancer. 50(3), 535-543. [Abstract]


  • Jonker, D., Karapetis, C., Harbison, C., O'Callaghan, C., Tu, D., Simes, R., Malone, D., Langer, C., Tebbutt, N., Price, T., Shapiro, J., Siu, L., Wong, R., Bjarnason, G., Moore, M., Zalcberg, J., Khambata-Ford, S. (2013), Epiregulin gene expression as a biomarker of benefit from cetuximab in the treatment of advanced colorectal cancer. British Journal of Cancer. 110(3), 648-655. [Abstract]
  • Lee, C., Simes, R., Brown, C., Gebski, V., Pfisterer, J., Swart, A., Berton-Rigaud, D., Plante, M., Skeie-Jensen, T., Vergote, I., Schauer, C., Pisano, C., Parma, G., Baumann, K., Ledermann, J., Pujade-Lauraine, E., Bentley, J., Kristensen, G., Belau, A., Nankivell, M., Canzler, U., Lord, S., Kurzeder, C., Friedlander, M. (2013), A prognostic nomogram to predict overall survival in patients with platinum-sensitive recurrent ovarian cancer. Annals of Oncology. 24(4), 937-943. [Abstract]
  • Nestel, P., Barnes, E., Tonkin, A., Simes, J., Fournier, M., White, H., Colquhoun, D., Blankenberg, S., Sullivan, D. (2013), Plasma lipoprotein(a) concentration predicts future coronary and cardiovascular events in patients with stable coronary heart disease. Arteriosclerosis, Thrombosis, and Vascular Biology. 33(12), 2902-2908. [Abstract]
  • White, H., Simes, J., Stewart, R., Blankenberg, S., Barnes, E., Marschner, I., Thompson, P., West, M., Zeller, T., Colquhoun, D., Nestel, P., Keech, A., Sullivan, D., Hunt, D., Tonkin, A. (2013), Changes in lipoprotein-Associated phospholipase A2 activity predict coronary events and partly account for the treatment effect of pravastatin: results from the Long-Term Intervention with Pravastatin in Ischemic Disease study. Journal of the American Heart Association. 2(5), e000360. [Abstract]
  • Winship, I., McNeil, J., Simes, R. (2013), A funding model for public-good clinical trials. The Medical Journal of Australia. 199(2), 90-91. [Abstract]
  • Siu, L., Shapiro, J., Jonker, D., Karapetis, C., Zalcberg, J., Simes, J., Couture, F., Moore, M., Price, T., Siddiqui, J., Nott, L., Charpentier, D., Liauw, W., Sawyer, M., Jefford, M., Magoski, N., Haydon, A., Walters, I., Ringash, J., Tu, D., O'Callaghan, C. (2013), Phase III randomized, placebo-controlled study of cetuximab plus brivanib alaninate versus cetuximab plus placebo in patients with metastatic, chemotherapy-refractory, wild-type K-RAS colorectal carcinoma: the NCIC Clinical Trials Group and AGITG CO.20 Trial. Journal of Clinical Oncology. 31(19), 2477-2484. [Abstract]
  • Anderson, C., Heeley, E., Huang, Y., Wang, J., Stapf, C., Delcourt, C., Lindley, R., Robinson, T., Lavados, P., Neal, B., Hata, J., Arima, H., Parsons, M., Li, Y., Wang, J., Heritier, S., Li, Q., Woodward, M., Simes, R., Davis, S., Chalmers, J. (2013), Rapid blood-pressure lowering in patients with acute intracerebral hemorrhage. The New England Journal of Medicine. 368(25), 2355-2365. [Abstract]
  • Price, T., Hardingham, J., Lee, C., Townsend, A., Wrin, J., Wilson, K., Weickhardt, A., Simes, R., Murone, C., Tebbutt, N. (2013), Prognostic impact and the relevance of PTEN copy number alterations in patients with advanced colorectal cancer (CRC) receiving bevacizumab. Cancer Medicine. 2(3), 277-285. [Abstract]
  • Stenson, B., Tarnow-Mordi, W., Darlow, B., Simes, J., Juszczak, E., Askie, L., Battin, M., Bowler, U., Broadbent, R., Cairns, P., Davis, P., Deshpande, S., Donoghoe, M., Doyle, L., Fleck, B., Ghadge, A., Hague, W., Halliday, H., Hewson, M., King, A., Kirby, A., Marlow, N., Meyer, M., Morley, C., Simmer, K., Tin, W., Wardle, S., Brocklehurst, P. (2013), Oxygen saturation and outcomes in preterm infants. The New England Journal of Medicine. 368(22), 2094-2104. [Abstract]
  • Vickers, M., Karapetis, C., Tu, D., O'Callaghan, C., Price, T., Tebbutt, N., Van Hazel, G., Shapiro, J., Pavlakis, N., Gibbs, P., Blondal, J., Lee, U., Meharchand, J., Burkes, R., Rubin, S., Simes, J., Zalcberg, J., Moore, M., Zhu, L., Jonker, D. (2013), Association of hypomagnesemia with inferior survival in a phase III, randomized study of cetuximab plus best supportive care versus best supportive care alone: NCIC CTG/AGITG CO.17. Annals of Oncology. 24(4), 953-960. [Abstract]
  • Brighton, T., Eikelboom, J., Simes, J. (2013), Aspirin for preventing venous thromboembolism. The New England Journal of Medicine. , 773. [Abstract]
  • Simes, R., Webb, S. (2013), Sustaining Australian research through clinical trials and investigator networks. Medical Journal of Australia. 198, 127-128. [Abstract]
  • Lee, C., Gebski, V., Coates, A., Veillard, A., Harvey, V., Tattersall, M., Byrne, M., Brigham, B., Forbes, J., Simes, R. (2013), Trade-offs in quality of life and survival with chemotherapy for advanced breast cancer: mature results of a randomized trial comparing single-agent mitoxantrone with combination cyclophosphamide, methotrexate, 5-fluorouracil and prednisone. SpringerPlus. 2, 391. [Abstract]
  • Martin, A., Simes, R. (2013), Quality-adjusted survival as an end point in breast cancer trials. Clinical Investigation. 3(6), 545-555.
  • Tarnow-Mordi, W., Simes, J., Cruz, M. (2013), Strategies to accelerate recruitment to NHMRC multi-centre clinical trials. Journal of Paediatrics and Child Health. , E103-105. [Abstract]


  • Dear, R., Barratt, A., Evans, A., Simes, J., Newsom, J., Kent, D., Crossing, S., Holliday, C., Segelov, E., Hruby, G., Tattersall, M. (2012), Identifying and prioritising gaps in colorectal cancer trials research in Australia. Medical Journal of Australia. 197(9), 507-511. [Abstract]
  • Brighton, T., Eikelboom, J., Mann, K., Mister, R., Gallus, A., Ockelford, P., Gibbs, H., Hague, W., Xavier, D., Diaz, R., Kirby, A., Simes, J. (2012), Low-Dose Aspirin for Preventing Recurrent Venous Thromboembolism. New England Journal of Medicine. 367(21), 1979-1987. [Abstract]
  • Mihaylova, B., Emberson, J., Blackwell, L., Keech, A., Simes, J., Barnes, E., Voysey, M., Gray, A., Collins, R., Baigent, C. (2012), The effects of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease: meta-analysis of individual data from 27 randomised trials. Lancet. 380(9841), 581-590. [Abstract]
  • Keech, A., Fulcher, J., Simes, J. (2012), The role of statin therapy in patients with lower vascular risk. Medical Journal of Australia. 197(3), 130-131. [Abstract]
  • Lee, C., Marschner, I., Simes, R., Voysey, M., Egleston, B., Hudes, G., de Souza, P. (2012), Increase in cholesterol predicts survival advantage in renal cell carcinoma patients treated with temsirolimus. Clinical Cancer Research. 18(11), 3188-3196. [Abstract]
  • Price, T., Zannino, D., Wilson, K., Simes, R., Cassidy, J., Van Hazel, G., Robinson, B., Broad, A., Ganju, V., Ackland, S., Tebbutt, N. (2012), Bevacizumab is equally effective and no more toxic in elderly patients with advanced colorectal cancer: a subgroup analysis from the AGITG MAX trial: an international randomised controlled trial of Capecitabine, Bevacizumab and Mitomycin C. Annals of Oncology. 23(6), 1531-1536. [Abstract]
  • Boekholdt, S., Arsenault, B., Mora, S., Pedersen, T., LaRosa, J., Nestel, P., Simes, R., Durrington, P., Hitman, G., Welch, K., DeMicco, D., Zwinderman, A., Clearfield, M., Downs, J., Tonkin, A., Colhoun, H., Gotto, A., Ridker, P., Kastelein, J. (2012), Association of LDL cholesterol, non-HDL cholesterol, and apolipoprotein B levels with risk of cardiovascular events among patients treated with statins: a meta-analysis. JAMA. 307(12), 1302-1309. [Abstract]
  • Verry, H., Lord, S., Martin, A., Gill, G., Lee, C., Howard, K., Wetzig, N., Simes, J. (2012), Effectiveness and cost-effectiveness of sentinel lymph node biopsy compared with axillary node dissection in patients with early-stage breast cancer: a decision model analysis. British Journal of Cancer. 106(6), 1045-1052. [Abstract]
  • Tonkin, A., Hunt, D., Voysey, M., Kesäniemi, A., Hamer, A., Waites, J., Mahar, L., Mann, S., Glasziou, P., Forder, P., Simes, J., Keech, A. (2012), Effects of fenofibrate on cardiovascular events in patients with diabetes, with and without prior cardiovascular disease: The Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) study. American Heart Journal. 163(3), 508-514. [Abstract]
  • Ting, R., Keech, A., Drury, P., Donoghoe, M., Hedley, J., Jenkins, A., Davis, T., Lehto, S., Celermajer, D., Simes, R., Rajamani, K., Stanton, K. (2012), Benefits and Safety of Long-Term Fenofibrate Therapy in People With Type 2 Diabetes and Renal Impairment: The FIELD study. Diabetes Care. 35(2), 218-225. [Abstract]
  • Emberson, J., Kearney, P., Blackwell, L., Newman, C., Reith, C., Bhala, N., Holland, L., Peto, R., Keech, A., Collins, R., Simes, J., Baigent, C. (2012), Lack of effect of lowering LDL cholesterol on cancer: meta-analysis of individual data from 175,000 people in 27 randomised trials of statin therapy. PLoS One. 7(1), e29849. [Abstract]
  • Staub, L., Dyer, S., Lord, S., Simes, R. (2012), Linking the evidence: intermediate outcomes in medical test assessments. International Journal of Technology Assessment in Health Care. 28(1), 52-58. [Abstract]
  • Staub, L., Lord, S., Simes, R., Dyer, S., Houssami, N., Chen, R., Irwig, L. (2012), Using patient management as a surrogate for patient health outcomes in diagnostic test evaluation. BMC Medical Research Methodology. 12, 12. [Abstract]


  • Stockler, M., Harvey, V., Francis, P., Byrne, M., Ackland, S., Fitzharris, B., Van Hazel, G., Wilcken, N., Grimison, P., Nowak, A., Gainford, M., Fong, A., Paksec, L., Sourjina, T., Zannino, D., Gebski, V., Simes, R., Forbes, J., Coates, A. (2011), Capecitabine Versus Classical Cyclophosphamide, Methotrexate, and Fluorouracil As First-Line Chemotherapy for Advanced Breast Cancer. Journal of Clinical Oncology. 29(34), 4498-4504. [Abstract]
  • Ananda, S., Nowak, A., Cher, L., Dowling, A., Brown, C., Simes, J., Rosenthal, M. (2011), Phase 2 trial of temozolomide and pegylated liposomal doxorubicin in the treatment of patients with glioblastoma multiforme following concurrent radiotherapy and chemotherapy. Journal of Clinical Neuroscience. 18(11), 1444-1448. [Abstract]
  • Sullivan, D., Forder, P., Simes, J., Whiting, M., Kritharides, L., Merrifield, A., Donoghoe, M., Colman, P., Graham, N., Haapamäki, H., Keech, A. (2011), Associations between the use of metformin, sulphonylureas, or diet alone and cardiovascular outcomes in 6005 patients with type 2 diabetes in the FIELD study. Diabetes research and clinical practice. 94(2), 284-90. [Abstract]
  • Lee, C., Simes, R., Brown, C., Lord, S., Wagner, U., Plante, M., Vergote, I., Pisano, C., Parma, G., Burges, A., Bourgeois, H., Högberg, T., Bentley, J., Angleitner-Boubenizek, L., Ferrero, A., Richter, B., Hirte, H., Gebski, V., Pfisterer, J., Pujade-Lauraine, E., Friedlander, M. (2011), Prognostic nomogram to predict progression-free survival in patients with platinum-sensitive recurrent ovarian cancer. British journal of cancer. 105(8), 1144-50. [Abstract]
  • Lee, C., Friedlander, M., Brown, C., Gebski, V., Georgoulopoulos, A., Vergote, I., Pignata, S., Donadello, N., Schmalfeldt, B., Delva, R., Mirza, M., Sauthier, P., Pujade-Lauraine, E., Lord, S., Simes, R. (2011), Early Decline in Cancer Antigen 125 as a Surrogate for Progression-Free Survival in Recurrent Ovarian Cancer. Journal of the National Cancer Institute. 103(17), 1338-42. [Abstract]
  • Lee, C., Hudson, M., Stockler, M., Coates, A., Ackland, S., Gebski, V., Lord, S., Friedlander, M., Boyle, F., Simes, R. (2011), A nomogram to predict survival time in women starting first-line chemotherapy for advanced breast cancer. Breast cancer research and treatment. 129(2), 467-76. [Abstract]
  • Goel, S., Simes, R., Beith, J. (2011), Exploratory analysis of cardiac biomarkers in women with normal cardiac function receiving trastuzumab for breast cancer. Asia-Pacific Journal of Clinical Oncology. 7(3), 276-280. [Abstract]
  • Clarke, S., Yip, S., Brown, C., van Hazel, G., Ransom, D., Goldstein, D., Jeffrey, G., Tebbut, N., Buck, M., Lowenthal, R., Boland, A., Gebski, V., Zalcberg, J., Simes, R. (2011), Single-agent irinotecan or 5-fluorouracil and leucovorin (FOLFIRI) as second-line chemotherapy for advanced colorectal cancer; results of a randomised phase II study (DaVINCI) and meta-analysis. European journal of cancer (Oxford, England : 1990). 47(12), 1826-36. [Abstract]
  • Tebbutt, N., Murphy, F., Zannino, D., Wilson, K., Cummins, M., Abdi, E., Strickland, A., Lowenthal, R., Marx, G., Karapetis, C., Shannon, J., Goldstein, D., Nayagam, S., Blum, R., Chantrill, L., Simes, R., Price, T. (2011), Risk of arterial thromboembolic events in patients with advanced colorectal cancer receiving bevacizumab. Annals of oncology : official journal of the European Society for Medical Oncology / ESMO. 22(8), 1834-8. [Abstract]
  • Lee, C., Gurney, H., Brown, C., Sorio, R., Donadello, N., Tulunay, G., Meier, W., Bacon, M., Maenpaa, J., Petru, E., Reed, N., Gebski, V., Pujade-Lauraine, E., Lord, S., Simes, R., Friedlander, M. (2011), Carboplatin-paclitaxel-induced leukopenia and neuropathy predict progression-free survival in recurrent ovarian cancer. British journal of cancer. 105(3), 360-5. [Abstract]
  • Sjoquist, K., Burmeister, B., Smithers, B., Zalcberg, J., Simes, R., Barbour, A., Gebski, V. (2011), Survival after neoadjuvant chemotherapy or chemoradiotherapy for resectable oesophageal carcinoma: an updated meta-analysis. The lancet oncology. 12(7), 681-92. [Abstract]
  • Dear, R., Barratt, A., McGeechan, K., Askie, L., Simes, J., Tattersall, M. (2011), Landscape of cancer clinical trials in Australia: using trial registries to guide future research. Medical Journal of Australia. 194(8), 387-391. [Abstract]
  • de Boer, S., Barnes, E., Westerhout, C., Simes, R., Granger, C., Kastrati, A., Widimsky, P., de Boer, M., Zijlstra, F., Boersma, E. (2011), High-risk patients with ST-elevation myocardial infarction derive greatest absolute benefit from primary percutaneous coronary intervention: results from the Primary Coronary Angioplasty Trialist versus thrombolysis (PCAT)-2 collaboration. American Heart Journal. 161(3), 500-507.e1. [Abstract]
  • Davis, T., Ting, R., Best, J., Donoghoe, M., Drury, P., Sullivan, D., Jenkins, A., O'Connell, R., Whiting, M., Glasziou, P., Simes, R., Kesäniemi, Y., Gebski, V., Scott, R., Keech, A. (2011), Effects of fenofibrate on renal function in patients with type 2 diabetes mellitus: the Fenofibrate Intervention and Event Lowering in Diabetes (FIELD) Study. Diabetologia. 54(0), 280-90. [Abstract]
  • Cox, K., Goel, S., O'Connell, R., Boyer, M., Beale, P., Simes, R., Stockler, M. (2011), A randomised crossover trial comparing inpatient and outpatient administration of high dose cisplatin. Internal medicine journal. (2). [Abstract]
  • Farrar, D., Duley, L., Burls, A., Dorling, J., Embleton, N., McGuire, W., Oddie, S., Simes, J., Tarnow-Mordi, W., Thornton, J., Tuffnell, D., Yoxall, B. (2011), Rushing to clamp umbilical cord. More evidence is needed to inform practice. BMJ. , d122. [Abstract]
  • Simes, J. (2011), Medical Oncology Group of Australia Cancer Achievement Award - Inspirations and influences for a life in clinical trials. Cancer Forum. 35:1, 48-50.


  • Baigent, C., Blackwell, L., Emberson, J., Holland, L., Reith, C., Bhala, N., Peto, R., Barnes, E., Keech, A., Simes, J., Collins, R. (2010), Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials. Lancet. 376(9753), 1670-81. [Abstract]
  • De Roock, W., Jonker, D., Di Nicolantonio, F., Sartore-Bianchi, A., Tu, D., Siena, S., Lamba, S., Arena, S., Frattini, M., Piessevaux, H., Van Cutsem, E., O'Callaghan, C., Khambata-Ford, S., Zalcberg, J., Simes, J., Karapetis, C., Bardelli, A., Tejpar, S. (2010), Association of KRAS p.G13D mutation with outcome in patients with chemotherapy-refractory metastatic colorectal cancer treated with cetuximab. JAMA: The Journal of the American Medical Association. 304(16), 1812-1820. [Abstract]
  • Taskinen, M., Barter, P., Ehnholm, C., Sullivan, D., Mann, K., Simes, J., Best, J., Hamwood, S., Keech, A. (2010), Ability of traditional lipid ratios and apolipoprotein ratios to predict cardiovascular risk in people with type 2 diabetes. Diabetologia. 53(9), 1846-1855. [Abstract]
  • Grimison, P., Stockler, M., Thomson, D., Olver, I., Harvey, V., Gebski, V., Lewis, C., Levi, J., Boyer, M., Gurney, H., Craft, P., Boland, A., Simes, R., Toner, G. (2010), Comparison of Two Standard Chemotherapy Regimens for Good-Prognosis Germ Cell Tumors: Updated Analysis of a Randomized Trial. Journal of the National Cancer Institute. 102(16), 1253-62. [Abstract]
  • Tebbutt, N., Wilson, K., Gebski, V., Cummins, M., Zannino, D., van Hazel, G., Robinson, B., Broad, A., Ganju, V., Ackland, S., Forgeson, G., Cunningham, D., Saunders, M., Stockler, M., Chua, Y., Zalcberg, J., Simes, R., Price, T. (2010), Capecitabine, Bevacizumab and Mitomycin in First-Line Treatment of Metastatic Colorectal Cancer: Results of the Australasian Gastrointestinal Trials Group Randomized, Phase III MAX Study. Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 28(19), 3191-8. [Abstract]
  • Simes, R., O'Connell, R., Aylward, P., Varshavsky, S., Diaz, R., Wilcox, R., Armstrong, P., Granger, C., French, J., Van de Werf, F., Marschner, I., Califf, R., White, H. (2010), Unexplained international differences in clinical outcomes after acute myocardial infarction and fibrinolytic therapy: Lessons from the Hirulog and Early Reperfusion or Occlusion (HERO)-2 trial. American Heart Journal. 159(6), 988-997. [Abstract]
  • Lee, C., Stockler, M., Coates, A., Gebski, V., Lord, S., Simes, R. (2010), Self-reported health-related quality of life is an independent predictor of chemotherapy treatment benefit and toxicity in women with advanced breast cancer. British journal of cancer. 102(9), 1341-7. [Abstract]
  • Califf, R., Armstrong, P., Granger, C., Harrington, R., Lee, K., Simes, R., Van de Werf, F., Wallentin, L., White, H. (2010), Towards a new order in cardiovascular medicine: re-engineering through global collaboration. European Heart Journal. 31(8), 911-917. [Abstract]
  • de Boer, S., Westerhout, C., Simes, R., Granger, C., Zijlstra, F., Boersma, E. (2010), Mortality and morbidity reduction by primary percutaneous coronary intervention is independent of the patient's age. JACC. Cardiovascular Interventions. 3(3), 324-331. [Abstract]
  • Lee, C., Lord, S., Stockler, M., Coates, A., Gebski, V., Simes, R. (2010), Historical cross-trial comparisons for competing treatments in advanced breast cancer - An empirical analysis of bias. European journal of cancer (Oxford, England : 1990). 46(3), 541-8. [Abstract]
  • Cui, J., Forbes, A., Kirby, A., Marschner, I., Simes, J., Hunt, D., West, M., Tonkin, A. (2010), Semi-parametric risk prediction models for recurrent cardiovascular events in the LIPID study. BMC Medical Research Methodology. 10, 27. [Abstract]
  • Askie, L., Baur, L., Campbell, K., Daniels, L., Hesketh, K., Magarey, A., Mihrshahi, S., Rissel, C., Simes, J., Taylor, B., Taylor, R., Voysey, M., Wen, L. (2010), The Early Prevention of Obesity in CHildren (EPOCH) Collaboration - an Individual Patient Data Prospective Meta-Analysis. BMC Public Health. 10, 728. [Abstract]
  • Simes, J., Voysey, M., O'Connell, R., Glasziou, P., Best, J., Scott, R., Pardy, C., Byth, K., Sullivan, D., Ehnholm, C., Keech, A. (2010), A novel method to adjust efficacy estimates for uptake of other active treatments in long-term clinical trials. PloS one. 5(1), e8580. [Abstract]


  • Cui, J., Forbes, A., Kirby, A., Simes, J., Tonkin, A. (2009), Laboratory and non-laboratory-based risk prediction models for secondary prevention of cardiovascular disease: the LIPID study. European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology. 16(6), 660-8. [Abstract]
  • Smith, M., Gill, P., Wetzig, N., Sourjina, T., Gebski, V., Ung, O., Campbell, I., Kollias, J., Coskinas, X., Macphee, A., Young, L., Simes, R., Stockler, M. (2009), Comparing patients' and clinicians' assessment of outcomes in a randomised trial of sentinel node biopsy for breast cancer (the RACS SNAC trial). Breast cancer research and treatment. 117(0), 99-109. [Abstract]
  • Grimison, P., Simes, R., Hudson, H., Stockler, M. (2009), Preliminary Validation of an Optimally Weighted Patient-Based Utility Index by Application to Randomized Trials in Breast Cancer. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research. 12(6), 967-76. [Abstract]
  • Berger, J., Elliott, L., Gallup, D., Roe, M., Granger, C., Armstrong, P., Simes, R., White, H., Van de Werf, F., Topol, E., Hochman, J., Newby, L., Harrington, R., Califf, R., Becker, R., Douglas, P. (2009), Sex differences in mortality following acute coronary syndromes. JAMA. 302(8), 874-882. [Abstract]
  • Taskinen, M., Sullivan, D., Ehnholm, C., Whiting, M., Zannino, D., Simes, R., Keech, A., Barter, P. (2009), Relationships of HDL cholesterol, ApoA-I, and ApoA-II with homocysteine and creatinine in patients with type 2 diabetes treated with fenofibrate. Arteriosclerosis, thrombosis, and vascular biology. 29(6), 950-955. [Abstract]
  • Lee, C., Lord, S., Coates, A., Simes, R. (2009), Molecular biomarkers to individualise treatment: assessing the evidence. The Medical Journal of Australia. 190(11), 631-636. [Abstract]
  • Carrick, S., Parker, S., Thornton, C., Ghersi, D., Simes, J., Wilcken, N. (2009), Single agent versus combination chemotherapy for metastatic breast cancer. Cochrane database of systematic reviews. 0(2), CD003372. [Abstract]
  • Gill, G., Wetzig, N., Gebski, V., Stockler, M., Ung, O., Campbell, I., Simes, J. (2009), Sentinel-Lymph-Node-Based Management or Routine Axillary Clearance? One-Year Outcomes of Sentinel Node Biopsy Versus Axillary Clearance (SNAC): A Randomized Controlled Surgical Trial. Annals of Surgical Oncology. 16(2), 266–275.
  • Mittmann, N., Au, H., Tu, D., O'Callaghan, C., Isogai, P., Karapetis, C., Zalcberg, J., Evans, W., Moore, M., Siddiqui, J., Findlay, B., Colwell, B., Simes, J., Gibbs, P., Links, M., Tebbutt, N., Jonker, D. (2009), Prospective Cost-Effectiveness Analysis of Cetuximab in Metastatic Colorectal Cancer: Evaluation of National Cancer Institute of Canada Clinical Trials Group CO.17 Trial. Journal of the National Cancer Institute. 101, 1182-1192. [Abstract]
  • Söderberg, S., Colquhoun, D., Keech, A., Yallop, J., Barnes, E., Pollicino, C., Simes, J., Tonkin, A., Nestel, P. (2009), Leptin, but not adiponectin, is a predictor of recurrent cardiovascular events in men: results from the LIPID study. International journal of obesity. 33(1), 123-130. [Abstract]
  • Clarke, P., Hayes, A., Glasziou, P., Scott, R., Simes, J., Keech, A. (2009), Using the EQ-5D index score as a predictor of outcomes in patients with type 2 diabetes. Medical care. 47(1), 61-68. [Abstract]
  • Grimison, P., Simes, R., Hudson, H., Stockler, M. (2009), Deriving a Patient-Based Utility Index from a Cancer-Specific Quality of Life Questionnaire. Value in health : the journal of the International Society for Pharmacoeconomics and Outcomes Research. 12(5), 800-7. [Abstract]


  • Karapetis, C., Khambata-Ford, S., Jonker, D., O'Callaghan, C., Tu, D., Tebbutt, N., Simes, R., Chalchal, H., Shapiro, J., Robitaille, S., Price, T., Shepherd, L., Au, H., Langer, C., Moore, M., Zalcberg, J. (2008), K-ras mutations and benefit from cetuximab in advanced colorectal cancer. The New England journal of medicine. 359(17), 1757-65. [Abstract]
  • Duric, V., Butow, P., Sharpe, L., Heritier, S., Boyle, F., Beith, J., Wilcken, N., Coates, A., Simes, R., Stockler, M. (2008), Comparing patients' and their partners' preferences for adjuvant chemotherapy in early breast cancer. Patient Education and Counseling. 72(2), 239-245. [Abstract]
  • Glasziou, P., Irwig, L., Heritier, S., Simes, R., Tonkin, A. (2008), Monitoring cholesterol levels: measurement error or true change?. Annals of Internal Medicine. 148(9), 656-661. [Abstract]
  • West, M., Nestel, P., Kirby, A., Schnabel, R., Sullivan, D., Simes, R., Pollicino, C., Lubos, E., Münzel, T., White, H., Tonkin, A., Bickel, C., Tiret, L., Blankenberg, S. (2008), The value of N-terminal fragment of brain natriuretic peptide and tissue inhibitor of metalloproteinase-1 levels as predictors of cardiovascular outcome in the LIPID study. European heart journal. 29(7), 923-931. [Abstract]
  • Hayes, A., Clarke, P., Glasziou, P., Simes, R., Drury, P., Keech, A. (2008), Can self-rated health scores be used for risk prediction in patients with type 2 diabetes?. Diabetes Care. 31(4), 795-797. [Abstract]
  • Berger, J., Stebbins, A., Granger, C., Ohman, E., Armstrong, P., Van de Werf, F., White, H., Simes, R., Harrington, R., Califf, R., Peterson, E. (2008), Initial aspirin dose and outcome among ST-elevation myocardial infarction patients treated with fibrinolytic therapy. Circulation. 117(2), 192-9. [Abstract]
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