Publications list for Professor MacDonald James Christie

2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008


  • Jin, A., Vetter, I., Dutertre, S., Abraham, N., Emidio, N., Inserra, M., Murali, S., Christie, M., Alewood, P., Lewis, R. (2014), MrIC, a Novel α-Conotoxin Agonist in the Presence of PNU at Endogenous [alpha]7 Nicotinic Acetylcholine Receptors. Biochemistry. 53(1), 1-3. [Abstract]


  • Bertran-Gonzalez, J., Laurent, V., Chieng, B., Christie, M., Balleine, B. (2013), Learning-related translocation of delta-opioid receptors on ventral striatal cholinergic interneurons mediates choice between goal-directed actions. The Journal of Neuroscience. 33(41), 16060-16071. [Abstract]
  • Knapman, A., Santiago, M., Du, Y., Bennallack, P., Christie, M., Connor, M. (2013), A Continuous, Fluorescence-based Assay of µ-Opioid Receptor Activation in AtT-20 Cells. Journal of Biomolecular Screening. 18(3), 269-276. [Abstract]
  • Brust, A., Wang, C., Daly, N., Kennerly, J., Sadeghi, M., Christie, M., Lewis, R., Mobli, M., Alewood, P. (2013), Vicinal Disulfide Constrained Cyclic Peptidomimetics: a Turn Mimetic Scaffold Targeting the Norepinephrine Transporter. Angewandte Chemie (International ed. in English). 52(46), 12020 ¿12023. [Abstract]
  • Saberi, S., Du, Y., Christie, M., Goldsbury, C. (2013), Human Chorionic Gonadotropin Increases Beta-Cleavage of Amyloid Precursor Protein in SH-SY5Y Cells. Cellular and Molecular Neurobiology. 33(6), 747-751. [Abstract]
  • Jayamanne, A., Jeong, H., Schroeder, C., Lewis, R., Christie, M., Vaughan, C. (2013), Spinal actions of ω-conotoxins, CVID, MVIIA and related peptides in a rat neuropathic pain model. British Journal of Pharmacology. 170(2), 245-254. [Abstract]
  • Sadeghi, M., Murali, S., Lewis, R., Alewood, P., Mohammadi, S., Christie, M. (2013), Novel [omega]-conotoxins from C. catus reverse signs of mouse inflammatory pain after systemic administration. Molecular Pain. 9(1), 51. [Abstract]
  • Williams, J., Ingram, S., Henderson, G., Chavkin, C., von Zastrow, M., Schulz, S., Koch, T., Evans, C., Christie, M. (2013), Regulation of μ-opioid receptors: desensitization, phosphorylation, internalization, and tolerance. Pharmacological Reviews. 65(1), 223-254. [Abstract]


  • Dang, V., Chieng, B., Christie, M. (2012), Prolonged Stimulation of μ-opioid Receptors Produces β-arrestin-2 Mediated Heterologous Desensitization of α2-adrenoceptor Function in Locus Coeruleus Neurons. Molecular Pharmacology. 82(3), 473-480. [Abstract]
  • Enoksson, T., Bertran-Gonzalez, J., Christie, M. (2012), Nucleus accumbens D2- and D1-receptor expressing medium spiny neurons are selectively activated by morphine withdrawal and acute morphine, respectively. Neuropharmacology. 62(8), 2463-2471. [Abstract]
  • Vetter, I., Mozar, C., Durek, T., Wingerd, J., Alewood, P., Christie, M., Lewis, R. (2012), Characterisation of Na(v) types endogenously expressed in human SH-SY5Y neuroblastoma cells. Biochemical Pharmacology. 83(11), 1562-1571. [Abstract]
  • Napier, I., Klimis, H., Rycroft, B., Jin, A., Alewood, P., Motin, L., Adams, D., Christie, M. (2012), Intrathecal α-conotoxins Vc1.1, AuIB and MII acting on distinct nicotinic receptor subtypes reverse signs of neuropathic pain. Neuropharmacology. 62(7), 2202-2207. [Abstract]
  • Murali, S., Napier, I., Rycroft, B., Christie, M. (2012), Opioid-related (ORL1) receptors are enriched in a subpopulation of sensory neurons and prolonged activation produces no functional loss of surface N-type calcium channels. Journal of Physiology. 590(Pt 7), 1655-1667. [Abstract]
  • Graeber, M., Christie, M. (2012), Multiple mechanisms of microglia: a gatekeeper's contribution to pain states. Experimental Neurology. 234(2), 255-261. [Abstract]
  • Lewis, R., Dutertre, S., Vetter, I., Christie, M. (2012), Conus venom peptide pharmacology. Pharmacological Reviews. 64(2), 259-298. [Abstract]
  • Dang, V., Christie, M. (2012), Mechanisms of rapid opioid receptor desensitization, resensitization and tolerance in brain neurons. British Journal of Pharmacology. 165(6), 1704-1716. [Abstract]
  • Napier, I., Mohammadi, S., Christie, M. (2012), Glutamate transporter dysfunction associated with nerve injury-induced pain in mice. Journal of Neurophysiology. 107(2), 649-657. [Abstract]


  • Bagley, E., Hacker, J., Chefer, V., Mallet, C., McNally, G., Chieng, B., Perroud, J., Shippenberg, T., Christie, M. (2011), Drug-induced GABA transporter currents enhance GABA release to induce opioid withdrawal behaviors. Nature neuroscience. 14(12), 1548-54. [Abstract]
  • Morgan, M., Christie, M. (2011), Analysis of Opioid Efficacy, Tolerance, Addiction, and Dependence from Cell Culture to Human. British journal of pharmacology. 164(4), 1322-34. [Abstract]
  • Pedersen, N., Vaughan, C., Christie, M. (2011), Opioid receptor modulation of GABAergic and serotonergic spinally-projecting neurons of the rostral ventromedial medulla in mice. Journal of neurophysiology. 106(2), 731-40. [Abstract]
  • Chieng, B., Azriel, Y., Mohammadi, S., Christie, M. (2011), Distinct cellular properties of identified dopaminergic and GABAergic neurons in the mouse ventral tegmental area. The Journal of physiology. 589(Pt 15), 3775-87. [Abstract]
  • de Araujo, A., Callaghan, B., Nevin, S., Daly, N., Craik, D., Moretta, M., Hopping, G., Christie, M., Adams, D., Alewood, P. (2011), Total synthesis of the analgesic conotoxin MrVIB through selenocysteine-assisted folding. Angewandte Chemie (International Edition). 50(29), 6527-6529. [Abstract]
  • Kawahara, H., Drew, G., Christie, M., Vaughan, C. (2011), Inhibition of fatty acid amide hydrolase unmasks CB(1) receptor and TRPV1 channel-mediated modulation of glutamatergic synaptic transmission in midbrain periaqueductal grey. British journal of pharmacology. 163(6), 1214-22. [Abstract]
  • Dang, V., Chieng, B., Azriel, Y., Christie, M. (2011), Cellular Morphine Tolerance Produced by {beta}Arrestin-2-Dependent Impairment of Opioid Receptor Resensitization. The Journal of Neuroscience. 31(19), 7122-7130. [Abstract]
  • Christie, M., Vaughan, C. (2011), Receptors: Cannabis medicine without a high. Nature Chemical Biology. 7(5), 249-250. [Abstract]
  • Klimis, H., Adams, D., Callaghan, B., Nevin, S., Alewood, P., Vaughan, C., Mozar, C., Christie, M. (2011), A novel mechanism of inhibition of high-voltage activated calcium channels by α-conotoxins contributes to relief of nerve injury-induced neuropathic pain. Pain. 152(2), 259-266. [Abstract]


  • Chieng, B., Christie, M. (2010), Somatostatin and nociceptin inhibit neurons in the central nucleus of amygdala that project to the periaqueductal grey. Neuropharmacology. 59(6), 425-30. [Abstract]
  • Morales, R., Daly, N., Vetter, I., Mobli, M., Napier, I., Craik, D., Lewis, R., Christie, M., King, G., Alewood, P., Durek, T. (2010), Chemical synthesis and structure of the prokineticin Bv8. Chembiochem. 11(13), 1882-1888. [Abstract]
  • Ittner, L., Ke, Y., Delerue, F., Bi, M., Gladbach, A., van Eersel, J., Wölfing, H., Chieng, B., Christie, M., Napier, I., Eckert, A., Staufenbiel, M., Hardeman, E., Götz, J. (2010), Dendritic Function of Tau Mediates Amyloid-beta Toxicity in Alzheimer's Disease Mouse Models. Cell. 142(3), 387-397. [Abstract]
  • Berecki, G., Motin, L., Haythornthwaite, A., Vink, S., Bansal, P., Drinkwater, R., Wang, C., Moretta, M., Lewis, R., Alewood, P., Christie, M., Adams, D. (2010), Analgesic omega-Conotoxins CVIE and CVIF Selectively and Voltage-Dependently Block Recombinant and Native N-Type Calcium Channels. Molecular Pharmacology. 77(2), 139-148. [Abstract]


  • Chieng, B., Christie, M. (2009), Chronic morphine treatment induces functional delta-opioid receptors in amygdala neurons that project to periaqueductal grey. Neuropharmacology. 57(4), 430-7. [Abstract]
  • Dang, V., Napier, I., Christie, M. (2009), Two distinct mechanisms mediate acute mu-opioid receptor desensitization in native neurons. Journal of Neuroscience. 29(10), 3322-3327. [Abstract]
  • Morgan, M., Ashley, M., Ingram, S., Christie, M. (2009), Behavioral Consequences of Delta-Opioid Receptor Activation in the Periaqueductal Gray of Morphine Tolerant Rats. Neural Plasticity. 2009, 516328. [Abstract]
  • Christie, M., Mallet, C. (2009), Endocannabinoids can open the pain gate. Science Signaling. 2(88), pe57. [Abstract]


  • Chieng, B., Lee, D., Du, Y., Osborne, P., Christie, M., Massotte, D. (2008), Functional coupling of mu-receptor-Galphai-tethered proteins in AtT20 cells. Neuroreport. 19(18), 1793-6. [Abstract]
  • Christie, M. (2008), Cellular neuroadaptations to chronic opioids: tolerance, withdrawal and addiction. British Journal of pharmacology. 154(2), 384-396. [Abstract]
  • Vikman, K., Rycroft, B., Christie, M. (2008), Switch to Ca2+ permeable AMPA and reduced NR2B NMDA receptor mediated neurotransmission at dorsal horn nociceptive synapses during inflammatory pain in the rat. The Journal of physiology. 586, 515-27. [Abstract]