Publications list for Dr Megan Chircop

2013 | 2012 | 2011 | 2010 | 2009 | 2008


  • McCluskey, A., Daniel, J., Hadzic, G., Chau, N., Clayton, E., Mariana, A., Whiting, A., Gorgani, N., Lloyd, J., Quan, A., Moshkanbaryans, L., Krishnan, S., Perera, S., Chircop, M., von Kleist, L., McGeachie, A., Howes, M., Parton, R., Campbell, M., Sakoff, J., Wang, X., Sun, J., Robertson, M., Deane, F., Nguyen, T., Meunier, F., Cousin, M., Robinson, P. (2013), Building a better dynasore: the dyngo compounds potently inhibit dynamin and endocytosis. Traffic. 14(12), 1272-1289. [Abstract]
  • McGeachie, A., Odell, L., Quan, A., Daniel, J., Chau, N., Hill, T., Gorgani, N., Keating, D., Cousin, M., van Dam, E., Mariana, A., Whiting, A., Perera, S., Novelle, A., Young, K., Deane, F., Gilbert, J., Sakoff, J., Chircop, M., McCluskey, A., Robinson, P. (2013), Pyrimidyn Compounds: Dual-Action Small Molecule Pyrimidine-Based Dynamin Inhibitors. ACS Chemical Biology. 8(7), 1507-1518. [Abstract]
  • Gordon, C., Venn-Brown, B., Robertson, M., Young, K., Chau, N., Mariana, A., Whiting, A., Chircop, M., Robinson, P., McCluskey, A. (2013), Development of second-generation indole-based dynamin GTPase inhibitors. Journal of Medicinal Chemistry. 56(1), 46-59. [Abstract]
  • Ma, M., Robinson, P., Chircop, M. (2013), Sorting nexin 9 recruits clathrin heavy chain to the mitotic spindle for chromosome alignment and segregation. PloS One. 8(7), e68387. [Abstract]
  • Boutros, R., Mondesert, O., Lorenzo, C., Astuti, P., McArthur, G., Chircop, M., Ducommun, B., Gabrielli, B. (2013), CDC25B Overexpression Stabilises Centrin 2 and Promotes the Formation of Excess Centriolar Foci. PloS One. 8(7), e67822. [Abstract]
  • Smith, C., Haucke, V., McCluskey, A., Robinson, P., Chircop, M. (2013), Inhibition of clathrin by pitstop 2 activates the spindle assembly checkpoint and induces cell death in dividing HeLa cancer cells. Molecular Cancer. 12, 4. [Abstract]


  • Ma, M., Chircop, M. (2012), SNX9, SNX18 and SNX33 are required for progression through and completion of mitosis. Journal of Cell Science. 125(Pt 18), 4372-4382. [Abstract]
  • Smith, C., Chircop, M. (2012), Clathrin-mediated endocytic proteins are involved in regulating mitotic progression and completion. Traffic. 13(12), 1628-1641. [Abstract]
  • Chircop, M. (2012), Protein Phosphatases Drive Mitotic Exit. In: Protein Kinases. (pp.215-228).Croatia: InTech.


  • Chircop, M., Sarcevic, B., Larsen, M., Malladi, C., Chau, N., Zavortink, M., Smith, C., Quan, A., Anggono, V., Hainsa, P., Graham, M., Robinson, P. (2011), Phosphorylation of dynamin II at serine-764 is associated with cytokinesis. Biochimica et biophysica acta. 1813(10), 1689-99. [Abstract]
  • Chircop, M., Perera, S., Mariana, A., Lau, H., Ma, M., Gilbert, J., Jones, N., Gordon, C., Young, K., Morokoff, A., Sakoff, J., O'Brien, T., McCluskey, A., Robinson, P. (2011), Inhibition of dynamin by dynole 34-2 induces cell death following cytokinesis failure in cancer cells. Molecular cancer therapeutics. 10(9), 1553-62. [Abstract]
  • von Kleist, L., Stahlschmidt, W., Bulut, H., Gromova, K., Puchkov, D., Robertson, M., MacGregor, K., Tomilin, N., Tomlin, N., Pechstein, A., Chau, N., Chircop, M., Sakoff, J., von Kries, J., Saenger, W., Kräusslich, H., Shupliakov, O., Robinson, P., McCluskey, A., Haucke, V. (2011), Role of the clathrin terminal domain in regulating coated pit dynamics revealed by small molecule inhibition. Cell. 146(3), 471-484. [Abstract]
  • Joshi, S., Braithwaite, A., Robinson, P., Chircop, M. (2011), Dynamin inhibitors induce caspase-mediated apoptosis following cytokinesis failure in human cancer cells and this is blocked by Bcl-2 overexpression. Molecular Cancer. 10, 78. [Abstract]


  • Chircop, M., Malladi, C., Lian, A., Page, S., Zavortink, M., Gordon, C., McCluskey, A., Robinson, P. (2010), Calcineurin activity is required for the completion of cytokinesis. Cellular and molecular life sciences : CMLS. 67, 3725-37. [Abstract]
  • Joshi, S., Perera, S., Gilbert, J., Smith, C., Mariana, A., Gordon, C., Sakoff, J., McCluskey, A., Robinson, P., Braithwaite, A., Chircop Nee Fabbro, M. (2010), The Dynamin Inhibitors MiTMAB and OcTMAB Induce Cytokinesis Failure and Inhibit Cell Proliferation in Human Cancer Cells. Molecular cancer therapeutics. 9(7), 1995-2006. [Abstract]


  • Hill, T., Gordon, C., McGeachie, A., Venn-Brown, B., Odell, L., Chau, N., Quan, A., Mariana, A., Sakoff, J., Chircop, M., Robinson, P., McCluskey, A. (2009), Inhibition of dynamin mediated endocytosis by the dynoles--synthesis and functional activity of a family of indoles. Journal of medicinal chemistry. 52(12), 3762-73. [Abstract]
  • Chircop, M., Oakes, V., Graham, M., Ma, M., Smith, C., Robinson, P., Khanna, K. (2009), The actin-binding and bundling protein, EPLIN, is required for cytokinesis. Cell Cycle. 8(5), 757-764. [Abstract]


  • Fabbro, M., Henderson, B. (2008), BARD1 regulates BRCA1-mediated transactivation of the p21(WAF1/CIP1) and Gadd45 promoters. Cancer letters. 263(2), 189-96. [Abstract]