Publications list for Associate Professor Nicholas Shackel

2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008


  • Grzelak, C., Martelotto, L., Sigglekow, N., Patkunanathan, B., Ajami, K., Calabro, S., Dwyer, B., Tirnitz-Parker, J., Neil Watkins, D., Warner, F., Shackel, N., McCaughan, G. (2014), The Intrahepatic Signalling Niche of Hedgehog is Defined by Primary Cilia Positive Cells During Chronic Liver Injury. Journal of Hepatology. 60(1), 143-151. [Abstract]


  • Williams, K., Shackel, N., Gorrell, M., McLennan, S., Twigg, S. (2013), Diabetes and Nonalcoholic Fatty Liver Disease: A Pathogenic Duo. Endocrine Reviews. 34(1), 84-129. [Abstract]
  • McLennan, S., Warner, F., Shackel, N. (2013), The role of CD147 in Liver Injury - "The truth is in the details". Journal of Hepatology. , 836-837. [Abstract]
  • Prakoso, E., Jones, C., Koorey, D., Strasser, S., Bowen, D., McCaughan, G., Shackel, N. (2013), Terlipressin Therapy for Moderate to Severe Hyponatremia in Patients with Liver Failure. Internal Medicine Journal. 43(3), 240-246. [Abstract]
  • Perera, N., Steinbeck, K., Shackel, N. (2013), The Adverse Health Consequences of the Use of Multiple Performance-Enhancing Substances-- A Deadly Cocktail. The Journal of Clinical Endocrinology and Metabolism. 98(12), 4613-4618. [Abstract]
  • Young, J., Ting, K., Li, J., Moller, T., Dunn, L., Lu, Y., Moses, J., Prado-Lourenco, L., Khachigian, L., Ng, M., Gregory, P., Goodall, G., Tsykin, A., Lichtenstein, I., Hahn, C., Tran, N., Shackel, N., Kench, J., McCaughan, G., Vadas, M., Gamble, J. (2013), Regulation of vascular leak and recovery from ischaemic injury by general and VE-cadherin-restricted miRNA antagonists of miR-27. Blood. 122(16), 2911-2919. [Abstract]
  • Pok, S., Wen, V., Shackel, N., Alsop, A., Pyakurel, P., Fahrer, A., Farrell, G., Teoh, N. (2013), Cyclin E facilitates dysplastic hepatocytes to bypass G1/S checkpoint in hepatocarcinogenesis. Journal of Gastroenterology and Hepatology. 28(9), 1545-1554. [Abstract]
  • Prakoso, E., Jones, C., Koorey, D., Strasser, S., Bowen, D., McCaughan, G., Shackel, N. (2013), Author reply.RE:Terlipressin therapy for moderate to severe hyponatraemia in patients with liver failure. Internal Medicine Journal. 43(5), 607. [Abstract]
  • Bowen, D., Shackel, N. (2013), Hepatitis C pathogenesis and outcomes post liver-transplantation: Probing microRNA expression for new insights. Liver Transplantation. 19, 355-357. [Abstract]
  • Tu, T., Shackel, N., McCaughan, G. (2013), "Testing your methyl": DNA methylation profiling of serum DNA of HCC patients. Hepatology International. 7, 785-787.
  • Chung, S., Shen, W., Jayawardana, K., Wang, P., Yang, J., Shackel, N., Gillies, M. (2013), Differential gene expression profiling after conditional muller-cell ablation in a novel transgenic model. Investigative Ophthalmology & Visual Science. 54(3), 2142-2152. [Abstract]


  • Rahman, W., Huang, P., Belov, L., Chrisp, J., Christopherson, R., Stapelberg, P., Warner, F., George, J., Bowen, D., Strasser, S., Koorey, D., Sharland, A., McCaughan, G., Shackel, N. (2012), Analysis of human liver disease using a cluster of differentiation (CD) antibody microarray. Liver International. 32(10), 1527-1534. [Abstract]
  • Shackel, N. (2012), When has the horse bolted?. Journal of Gastroenterology and Hepatology. 27(7), 1133-1134. [Abstract]
  • Shackel, N. (2012), Looking into Pandora's box. Liver Transplantation. 18, 274-276. [Abstract]
  • de Graaf, E., Kench, J., Dilworth, P., Shackel, N., Strasser, S., Joseph, D., Pleass, H., Crawford, M., McCaughan, G., Verran, D. (2012), Grade of Deceased Donor Liver Macrovesicular Steatosis Impacts Graft and Recipient Outcomes More than Donor Risk Index. Journal of Gastroenterology and Hepatology. 27(3), 540-546. [Abstract]
  • Tan, S., Cavanagh, L., d'Advigor, W., Shackel, N., de St Groth, B., Weninger, W. (2012), Phenotype and functions of conventional dendritic cells are not compromised in aged mice. Immunology and Cell Biology. 90(7), 722-732. [Abstract]


  • Song, S., Shackel, N., Wang, X., Ajami, K., McCaughan, G., Gorrell, M. (2011), Discoidin domain receptor 1: isoform expression and potential functions in cirrhotic human liver. The American Journal of Pathology. 178(3), 1134-1144. [Abstract]
  • McCaughan, G., Shackel, N., Bowen, D. (2011), Liver transplantation and hepatitis C: will understanding the interleukin-28B polymorphisms improve outcomes?. Liver Transplantation. 17, 219-221. [Abstract]


  • Shackel, N. (2010), The balancing act of hepatocyte apoptosis. Hepatology. 52(6), 2231-2233. [Abstract]
  • Bao, W., Min, D., Twigg, S., Shackel, N., Warner, F., Yue, D., McLennan, S. (2010), Monocyte CD147 is induced by Advanced Glycation Endproducts (AGEs) and High Glucose Concentration: Possible role in diabetic complications. American journal of physiology. Cell physiology. 299(5), C1212-9. [Abstract]
  • Prakoso, E., Verran, D., Dilworth, P., Kyd, G., Tang, P., Tse, C., Koorey, D., Strasser, S., Stormon, M., Shun, A., Thomas, G., Joseph, D., Pleass, H., Gallagher, J., Allen, R., Crawford, M., McCaughan, G., Shackel, N. (2010), Increasing liver transplantation waiting list mortality: a report from the Australian National Liver Transplantation Unit, Sydney. Internal Medicine Journal. 40(9), 619-625. [Abstract]
  • McCaughan, G., Shackel, N., Strasser, S., Dilworth, P., Tang, P. (2010), Minimal but significant improvement in survival for non-hepatitis C-related adult liver transplant patients beyond the one-year posttransplant mark. Liver Transplantation. 16(2), 130-137. [Abstract]
  • Shackel, N., Bowen, D., McCaughan, G. (2010), Snipping away at hepatitis C. Hepatology. 51(2), 703-705. [Abstract]


  • Sandroussi, C., Crawford, M., Lockwood, D., Tang, P., Gallagher, J., Pleass, H., Strasser, S., Shackel, N., McCaughan, G., Verran, D. (2009), Donor and recipient selection leads to good patient and graft outcomes for right lobe split transplantation versus whole graft liver transplantation in adult recipients. Liver Transplantation. 15(11), 1586-1593. [Abstract]
  • Shackel, N. (2009), Liver "tick tock". Hepatology. 50(4), 1310-1311. [Abstract]
  • Eckersley-Maslin, M., Warner, F., Grzelak, C., McCaughan, G., Shackel, N. (2009), Bone marrow stem cells and the liver: are they relevant?. Journal of Gastroenterology and Hepatology. 24(10), 1608-1616. [Abstract]
  • Shackel, N., Jamias, J., Rahman, W., Prakoso, E., Strasser, S., Koorey, D., Crawford, M., Verran, D., Gallagher, J., McCaughan, G. (2009), Early high peak hepatitis C viral load levels independently predict hepatitis C-related liver failure post-liver transplantation. Liver Transplantation. 15(7), 709-718. [Abstract]
  • McCaughan, G., Shackel, N., Bertolino, P., Bowen, D. (2009), Molecular and cellular aspects of hepatitis C virus reinfection after liver transplantation: how the early phase impacts on outcomes. Transplantation. 87(8), 1105-1111. [Abstract]
  • Bowen, D., Zekry, A., Bertolino, P., Shackel, N., McCaughan, G. (2009), Pathology and pathogenesis of hepatitis C. In: Hepatitis C: An Expanding Perspective. (pp.43-75).Australia: IP Communications.
  • Gaudieri, S., Rauch, A., Pfafferott, K., Barnes, E., Cheng, W., McCaughan, G., Shackel, N., Jeffrey, G., Mollison, L., Baker, R., Furrer, H., Gunthard, H., Freitas, E., Humphreys, I., Klenerman, P., Mallal, S., James, I., Roberts, S., Nolan, D., Lucas, M. (2009), Hepatitis C Virus Drug Resistance and Immune-Driven Adaptations: Relevance to New Antiviral Therapy. Hepatology. 49(4), 1069-1082. [Abstract]
  • Rauch, A., James, I., Pfafferott, K., Nolan, D., Klenerman, P., Cheng, W., Mollison, L., McCaughan, G., Shackel, N., Jeffrey, G., Baker, R., Freitas, E., Humphreys, I., Furrer, H., Gunthard, H., Hirschel, B., Mallal, S., John, M., Lucas, M., Barnes, E., Gaudieri, S. (2009), Diverged Adaptation of Hepatitis C Virus Genotypes 1 and 3 to Human Leukocyte Antigen-Restricted Immune Pressure. Hepatology. 50(4), 1017-1029. [Abstract]


  • Shackel, N., McCaughan, G., Warner, F. (2008), Hepatocellular carcinoma development requires hepatic stem cells with altered transforming growth factor and interleukin-6 signaling. Hepatology (Baltimore, Md.). 47(6), 2134-6. [Abstract]