Publications list for Professor Nicholas Hunt

2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008

2014

   
  • Too, L., Ball, H., McGregor, I., Hunt, N. (2014), A novel automated test battery reveals enduring behavioural alterations and cognitive impairments in survivors of murine pneumococcal meningitis. Brain, Behavior, and Immunity. 35, 107¿124. [Abstract]

2013

   
  • Fatokun, A., Hunt, N., Ball, H. (2013), Indoleamine 2,3-dioxygenase 2 (IDO2) and the kynurenine pathway: characteristics and potential roles in health and disease. Amino Acids. 45(6), 1319-1329. [Abstract]
  • El-Assaad, F., Wheway, J., Mitchell, A., Lou, J., Hunt, N., Combes, V., Grau, G. (2013), Cytoadherence of Plasmodium berghei-infected red blood cells to murine brain and lung microvascular endothelial cells in vitro. Infection and Immunity. 81(11), 3984-3991. [Abstract]
  • Machaalani, R., Hunt, N., Waters, K. (2013), Effects of changes in energy homeostasis and exposure of noxious insults on the expression of orexin (hypocretin) and its receptors in the brain. Brain Research. 1526, 102-122. [Abstract]
  • Jusof, F., Khaw, L., Ball, H., Hunt, N. (2013), Improved spectrophotometric human interferon-gamma bioassay. Journal of Immunological Methods. 394(1-2), 115-120. [Abstract]
  • Hunt, N., Waters, K., Machaalani, R. (2013), Orexin receptors in the developing piglet hypothalamus, and effects of nicotine and intermittent hypercapnic hypoxia exposures. Brain Research. 1508, 73-82. [Abstract]
  • Golenser, J., Hunt, N. (2013), Neglected aspects of drug discovery-microbiological aspects. Current Clinical Pharmacology. 8(1), 73-80. [Abstract]
  • Lee, J., Siegele, R., Pastuovic, Z., Hackett, M., Hunt, N., Grau, G., Cohen, D., Lay, P. (2013), Light and heavy ion beam analysis of thin biological sections. Nuclear Instruments and Methods in Physics Research B. 306, 129-133.
  • Khaw, L., Ball, H., Golenser, J., Combes, V., Grau, G., Wheway, J., Mitchell, A., Hunt, N. (2013), Endothelial Cells Potentiate Interferon-γ Production in a Novel Tripartite Culture Model of Human Cerebral Malaria. PloS One. 8(7), e69521. [Abstract]

2012

   
  • Hackett, M., Lee, J., El-Assaad, F., McQuillan, J., Carter, E., Grau, G., Hunt, N., Lay, P. (2012), FTIR Imaging of Brain Tissue Reveals Crystalline Creatine Deposits Are an ex Vivo Marker of Localized Ischemia during Murine Cerebral Malaria: General Implications for Disease Neurochemistry. ACS Chemical Neuroscience. 3(12), 1017-1024. [Abstract]
  • Mitchell, A., Yau, B., McQuillan, J., Ball, H., Too, L., Abtin, A., Hertzog, P., Leib, S., Jones, C., Gerega, S., Weninger, W., Hunt, N. (2012), Inflammasome-Dependent IFN-γ Drives Pathogenesis in Streptococcus pneumoniae Meningitis. Journal of Immunology. 189(10), 4970-4980. [Abstract]
  • Bakmiwewa, S., Fatokun, A., Tran, A., Payne, R., Hunt, N., Ball, H. (2012), Identification of selective inhibitors of indoleamine 2,3-dioxygenase 2. Bioorganic & Medicinal Chemistry Letters. 22(24), 7641-7346. [Abstract]
  • Combes, V., Guillemin, G., Chan-Ling, T., Hunt, N., Grau, G. (2012), The crossroads of neuroinflammation in infectious diseases: endothelial cells and astrocytes. Trends in Parasitology. 28(8), 311-319. [Abstract]
  • Guo, J., Guiguemde, A., Bentura-Marciano, A., Clark, J., Haynes, R., Chan, W., Wong, H., Hunt, N., Guy, R., Golenser, J. (2012), Synthesis of Artemiside and Its Effects in Combination with Conventional Drugs, Against Severe Murine Malaria. Antimicrobial agents and chemotherapy. 56(1), 163-73. [Abstract]
  • Lam, Y., Ha, C., Campbell, C., Mitchell, A., Dinudom, A., Oscarsson, J., Cook, D., Hunt, N., Caterson, I., Holmes, A., Storlien, L. (2012), Increased gut permeability and microbiota change associate with mesenteric fat inflammation and metabolic dysfunction in diet-induced obese mice. PLoS One. 7(3), e34233. [Abstract]

2011

   
  • Hunt, N. (2011), Redox Pioneer: Professor Roland Stocker. Antioxidants & redox signaling. 15(12), 3101-5. [Abstract]
  • Conroy, T., Guo, J., Linington, R., Hunt, N., Payne, R. (2011), Total synthesis, stereochemical assignment, and antimalarial activity of gallinamide A. Chemistry (Weinheim an der Bergstrasse, Germany). 17(48), 13544-52. [Abstract]
  • Bao, S., Carr, E., Xu, Y., Hunt, N. (2011), Gp91(phox) contributes to the development of experimental inflammatory bowel disease. Immunology and cell biology. 89(8), 853-60. [Abstract]
  • Lam, Y., Mitchell, A., Holmes, A., Denyer, G., Gummesson, A., Caterson, I., Hunt, N., Storlien, L. (2011), Role of the Gut in Visceral Fat Inflammation and Metabolic Disorders. Obesity (Silver Spring, Md.). 19(11), 2113-20. [Abstract]
  • Hempel, C., Combes, V., Hunt, N., Lindholm Kurtzhals, J., Raymond Grau, G. (2011), CNS Hypoxia Is More Pronounced in Murine Cerebral than Noncerebral Malaria and Reversed by Erythropoietin. American Journal of Pathology. 179(4), 1939-1950. [Abstract]
  • Ampawong, S., Combes, V., Hunt, N., Radford, J., Chan-Ling, T., Pongponratn, E., Grau, G. (2011), Quantitation of brain edema and localisation of aquaporin 4 expression in relation to susceptibility to experimental cerebral malaria. International Journal of Clinical and Experimental Pathology. 4(6), 566-574. [Abstract]
  • Hackett, M., McQuillan, J., El-Assaad, F., Aitken, J., Levina, A., Cohen, D., Siegele, R., Carter, E., Grau, G., Hunt, N., Lay, P. (2011), Chemical alterations to murine brain tissue induced by formalin fixation: implications for biospectroscopic imaging and mapping studies of disease pathogenesis. The Analyst. 136(14), 2941-2952. [Abstract]
  • El-Assaad, F., Hempel, C., Combes, V., Mitchell, A., Ball, H., Kurtzhals, J., Hunt, N., Mathys, J., Grau, G. (2011), Differential microRNA expression in experimental cerebral and non-cerebral malaria. Infection and Immunity. 79(6), 2379-2384. [Abstract]
  • McQuillan, J., Mitchell, A., Ho, Y., Combes, V., Ball, H., Golenser, J., Grau, G., Hunt, N. (2011), Coincident parasite and CD8 T cell sequestration is required for development of experimental cerebral malaria. International Journal for Parasitology. 41(2), 155-163. [Abstract]
  • Hackett, M., Siegele, R., El-Assaad, F., McQuillan, J., Aitken, J., Carter, E., Grau, G., Hunt, N., Cohen, D., Lay, P. (2011), Investigation of the mouse cerebellum using STIM and l-PIXE spectrometric and FTIR spectroscopic mapping and imaging. Nuclear Instruments and Methods in Physics Research B. 269(20), 2260-2263.
  • Hee, L., Dinudom, A., Mitchell, A., Grau, G., Cook, D., Hunt, N., Ball, H. (2011), Reduced activity of the epithelial sodium channel in malaria-induced pulmonary edema in mice. International Journal for Parasitology. 41(1), 81-88. [Abstract]

2010

   
  • Conroy, T., Guo, J., Hunt, N., Payne, R. (2010), Total Synthesis and Antimalarial Activity of Symplostatin 4. Organic letters. 12(23), 5576-9. [Abstract]
  • Yuasa, H., Ball, H., Austin, C., Hunt, N. (2010), 1-l-methyltryptophan is a more effective inhibitor of vertebrate IDO2 enzymes than 1-d-methyltryptophan. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 157(1), 10-5. [Abstract]
  • Mitchell, A., Pradel, L., Chasson, L., Van Rooijen, N., Grau, G., Hunt, N., Chimini, G. (2010), Technical Advance: Autofluorescence as a tool for myeloid cell analysis. Journal of leukocyte biology. 88(3), 597-603. [Abstract]
  • Austin, C., Mailu, B., Maghzal, G., Sanchez-Perez, A., Rahlfs, S., Zocher, K., Yuasa, H., Arthur, J., Becker, K., Stocker, R., Hunt, N., Ball, H. (2010), Biochemical characteristics and inhibitor selectivity of mouse indoleamine 2,3-dioxygenase-2. Amino acids. 39(2), 565-78. [Abstract]
  • Waknine-Grinberg, J., McQuillan, J., Hunt, N., Ginsburg, H., Golenser, J. (2010), Modulation of cerebral malaria by fasudil and other immune-modifying compounds. Experimental Parasitology. 125(2), 141-146. [Abstract]
  • Hunt, N., Grau, G., Engwerda, C., Barnum, S., van der Heyde, H., Hansen, D., Schofield, L., Golenser, J. (2010), Murine cerebral malaria: the whole story. Trends in parasitology. , 272-4. [Abstract]
  • Combes, V., El-Assaad, F., Faille, D., Jambou, R., Hunt, N., Grau, G. (2010), Microvesiculation and cell interactions at the brain-endothelial interface in cerebral malaria pathogenesis. Progress in Neurobiology. 91(2), 140-151. [Abstract]
  • Wang, Y., Liu, H., McKenzie, G., Witting, P., Stasch, J., Hahn, M., Changsirivathanathamrong, D., Wu, B., Ball, H., Thomas, S., Kapoor, V., Celermajer, D., Mellor, A., Keaney, J., Hunt, N., Stocker, R. (2010), Kynurenine is an endothelium-derived relaxing factor produced during inflammation. Nature Medicine. 16(3), 279-285. [Abstract]
  • Waknine-Grinberg, J., Hunt, N., Bentura-Marciano, A., McQuillan, J., Chan, H., Chan, W., Barenholz, Y., Haynes, R., Golenser, J. (2010), Artemisone effective against murine cerebral malaria. Malaria Journal. 9, 227. [Abstract]

2009

   
  • Krimmer, D., Loseli, M., Hughes, J., Oliver, B., Moir, L., Hunt, N., Black, J., Burgess, J. (2009), CD40 and OX40 ligand are differentially regulated on asthmatic airway smooth muscle. Allergy. 64(7), 1074-82. [Abstract]
  • Yuasa, H., Ball, H., Ho, Y., Austin, C., Whittington, C., Belov, K., Maghzal, G., Jermiin, L., Hunt, N. (2009), Characterization and evolution of vertebrate indoleamine 2, 3-dioxygenases IDOs from monotremes and marsupials. Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology. 153(2), 137-144. [Abstract]
  • Ball, H., Yuasa, H., Austin, C., Weiser, S., Hunt, N. (2009), Indoleamine 2,3-dioxygenase-2; a new enzyme in the kynurenine pathway. The international journal of biochemistry & cell biology. 41(0), 467-71. [Abstract]
  • Miu, J., Ball, H., Mellor, A., Hunt, N. (2009), Effect of indoleamine dioxygenase-1 deficiency and kynurenine pathway inhibition on murine cerebral malaria. International journal for parasitology. 39(0), 363-70. [Abstract]
  • Austin, C., Astelbauer, F., Kosim-Satyaputra, P., Ball, H., Willows, R., Jamie, J., Hunt, N. (2009), Mouse and human indoleamine 2,3-dioxygenase display some distinct biochemical and structural properties. Amino acids. 36(0), 99-106. [Abstract]

2008

   
  • Xu, Y., Hunt, N., Bao, S. (2008), The role of granulocyte macrophage-colony-stimulating factor in acute intestinal inflammation. Cell research. 18(0), 1220-9. [Abstract]
  • Belnoue, E., Potter, S., Rosa, D., Mauduit, M., Grüner, A., Kayibanda, M., Mitchell, A., Hunt, N., Rénia, L. (2008), Control of pathogenic CD8+ T cell migration to the brain by IFN-gamma during experimental cerebral malaria. Parasite Immunology. 30(10), 544-553. [Abstract]
  • Burgess, J., Lee, J., Ge, Q., Ramsay, E., Poniris, M., Parmentier, J., Roth, M., Johnson, P., Hunt, N., Black, J., Ammit, A. (2008), Dual ERK and phosphatidylinositol 3-kinase pathways control airway smooth muscle proliferation: Differences in asthma. Journal of cellular physiology. 216(3), 673-9. [Abstract]
  • Xu, Y., Hunt, N., Bao, S. (2008), The effect of restraint stress on experimental colitis is IFN-gamma independent. Journal of neuroimmunology. 200(0), 53-61. [Abstract]
  • Maghzal, G., Thomas, S., Hunt, N., Stocker, R. (2008), Cytochrome b5, not superoxide anion radical, is a major reductant of indoleamine 2,3-dioxygenase in human cells. Journal of Biological Chemistry. 283(18), 12014-12025. [Abstract]
  • Miu, J., Hunt, N., Ball, H. (2008), Predominance of interferon-related responses in the brain during murine malaria, as identified by microarray analysis. Infection and Immunity. 76(5), 1812-1824. [Abstract]
  • Boeuf, P., Tan, A., Romagosa, C., Radford, J., Mwapasa, V., Molyneux, M., Meshnick, S., Hunt, N., Rogerson, S. (2008), Placental hypoxia during placental malaria. The Journal of Infectious Diseases. 197(5), 757-765. [Abstract]
  • Miu, J., Mitchell, A., Müller, M., Carter, S., Manders, P., McQuillan, J., Saunders, B., Ball, H., Lu, B., Campbell, I., Hunt, N. (2008), Chemokine gene expression during fatal murine cerebral malaria and protection due to CXCR3 deficiency. Journal of immunology. 180(2), 1217-30. [Abstract]
  • Togbe, D., de Sousa, P., Fauconnier, M., Boissay, V., Fick, L., Scheu, S., Pfeffer, K., Menard, R., Grau, G., Doan, B., Beloeil, J., Renia, L., Hansen, A., Ball, H., Hunt, N., Ryffel, B., Quesniaux, V. (2008), Both functional LTbeta receptor and TNF receptor 2 are required for the development of experimental cerebral malaria. PloS one. 3(7), e2608. [Abstract]