Publications list for Professor Patrick Tam

2012 | 2011 | 2010 | 2009 | 2008 | 2007

2012

   
  • Stephenson, R., Rossant, J., Tam, P. (2012), Intercellular interactions, position, and polarity in establishing blastocyst cell lineages and embryonic axes. Cold Spring Harbor Perspectives in Biology. 4(11), a008235. [Abstract]
  • Arkell, R., Tam, P. (2012), Initiating head development in mouse embryos: integrating signalling and transcriptional activity. Open Biology. 2(3), 120030. [Abstract]
  • Loebel, D., Hor, A., Bildsoe, H., Jones, V., Chen, Y., Behringer, R., Tam, P. (2012), Regionalized Twist1 activity in the forelimb bud drives the morphogenesis of the proximal and preaxial skeleton. Developmental biology. 362(2), 132-40. [Abstract]
  • Williamson, S., Giudici, L., Kilstrup-Nielsen, C., Gold, W., Pelka, G., Tam, P., Grimm, A., Prodi, D., Landsberger, N., Christodoulou, J. (2012), A novel transcript of cyclin-dependent kinase-like 5 (CDKL5) has an alternative C-terminus and is the predominant transcript in brain. Human Genetics. 131(2), 187-200. [Abstract]
  • Loebel, D., Tam, P. (2012), Rho GTPases in endoderm development and differentiation. Small GTPases. 3(1), 40-44. [Abstract]
  • Fossat, N., Jones, V., Garcia-Garcia, M., Tam, P. (2012), Modulation of WNT signaling activity is key to the formation of the embryonic head. Cell Cycle. 11(1), 26-32. [Abstract]

2011

   
  • Tam, P. (2011), Endoderm formation: not so black and white anymore. Developmental Cell. 21(4), e2. [Abstract]
  • Loebel, D., Studdert, J., Power, M., Radziewic, T., Jones, V., Coultas, L., Jackson, Y., Rao, R., Steiner, K., Fossat, N., Robb, L., Tam, P. (2011), Rhou maintains the epithelial architecture and facilitates differentiation of the foregut endoderm. Development. 138(20), 4511-4522. [Abstract]
  • Tanaka, S., Kojima, Y., Yamaguchi, Y., Nishinakamura, R., Tam, P. (2011), Impact of WNT signaling on tissue lineage differentiation in the early mouse embryo. Development, growth & differentiation. 53(7), 843-56. [Abstract]
  • Fossat, N., Jones, V., Khoo, P., Bogani, D., Hardy, A., Steiner, K., Mukhopadhyay, M., Westphal, H., Nolan, P., Arkell, R., Tam, P. (2011), Stringent requirement of a proper level of canonical WNT signalling activity for head formation in mouse embryo. Development. 138(4), 667-676. [Abstract]
  • Pfister, S., Jones, V., Power, M., Truisi, G., Khoo, P., Steiner, K., Kanai-Azuma, M., Kanai, Y., Tam, P., Loebel, D. (2011), Sox17-dependent gene expression and early heart and gut development in Sox17-deficient mouse embryos. The International Journal of Developmental Biology. 55(1), 45-58. [Abstract]
  • Fossat, N., Loebel, D., Jones, V., Khoo, P., Bildsoe, H., Tam, P. (2011), Marking Cells for Imaging Analysis of Morphogenetic Behavior and Cell Fates in Mouse Embryos. In: Imaging in Developmental Biology: A Laboratory Manual. (pp.311-329).United States: Cold Spring Harbor Laboratory Press.
  • Combes, A., Bowles, J., Feng, C., Chiu, H., Khoo, P., Jackson, A., Little, M., Tam, P., Koopman, P. (2011), Expression and functional analysis of Dkk1 during early gonadal development. Sexual Development. 5(3), 124-130. [Abstract]

2010

   
  • Tanaka, S., Yamaguchi, Y., Steiner, K., Nakano, T., Nishinakamura, R., Kwan, K., Behringer, R., Tam, P. (2010), Loss of Lhx1 activity impacts on the localization of primordial germ cells in the mouse. Developmental dynamics : an official publication of the American Association of Anatomists. 239(11), 2851-9. [Abstract]
  • Weaving, L., Mihelec, M., Storen, R., Sosic, D., Grigg, J., Tam, P., Jamieson, R. (2010), Twist2: Role in Corneal Stromal Keratocyte Proliferation and Corneal Thickness. Investigative ophthalmology & visual science. 51(11), 5561-70. [Abstract]
  • Leung, A., Wong, S., Chan, D., Tam, P., Cheah, K. (2010), Loss of procollagen IIA from the anterior mesendoderm disrupts the development of mouse embryonic forebrain. Developmental Dynamics. 239(9), 2319-2329. [Abstract]
  • Fath, T., Agnes Chan, Y., Vrhovski, B., Clarke, H., Curthoys, N., Hook, J., Lemckert, F., Schevzov, G., Tam, P., Watson, C., Khoo, P., Gunning, P. (2010), New aspects of tropomyosin-regulated neuritogenesis revealed by the deletion of Tm5NM1 and 2. European journal of cell biology. 89(7), 489-98. [Abstract]
  • Pera, M., Tam, P. (2010), Extrinsic regulation of pluripotent stem cells. Nature. 465(7299), 713-720. [Abstract]
  • Harikrishnan, K., Bayles, R., Ciccotosto, G., Maxwell, S., Cappai, R., Pelka, G., Tam, P., Christodoulou, J., El-Osta, A. (2010), Alleviating transcriptional inhibition of the norepinephrine slc6a2 transporter gene in depolarized neurons. The Journal of Neuroscience. 30(4), 1494-1501. [Abstract]
  • Rivera-Pérez, J., Jones, V., Tam, P. (2010), Culture of Whole Mouse Embryos at Early Postimplantation to Organogenesis Stages: Developmental Staging and Methods. In: Methods in Enzymology: Guide to Techniques in Mouse Development, Part A: Mice, Embryos, and Cells. (pp.185-203).United States: Elsevier Inc..

2009

   
  • Mihelec, M., Abraham, P., Gibson, K., Krowka, R., Susman, R., Storen, R., Chen, Y., Donald, J., Tam, P., Grigg, J., Flaherty, M., Gole, G., Jamieson, R. (2009), Novel SOX2 partner-factor domain mutation in a four-generation family. European journal of human genetics : EJHG. 17(11), 1417-22. [Abstract]
  • Bildsoe, H., Loebel, D., Jones, V., Chen, Y., Behringer, R., Tam, P. (2009), Requirement for Twist1 in frontonasal and skull vault development in the mouse embryo. Developmental Biology. 331(2), 176-188. [Abstract]
  • Grassinger, J., Haylock, D., Storan, M., Haines, G., Williams, B., Whitty, G., Vinson, A., Be, C., Li, S., Sørensen, E., Tam, P., Denhardt, D., Sheppard, D., Choong, P., Nilsson, S. (2009), Thrombin-cleaved osteopontin regulates hemopoietic stem and progenitor cell functions through interactions with alpha9beta1 and alpha4beta1 integrins. Blood. 114(1), 49-59. [Abstract]
  • Tam, P., Loebel, D. (2009), Specifying mouse embryonic germ cells. Cell. 137(3), 398-400. [Abstract]
  • Rossant, J., Tam, P. (2009), Blastocyst lineage formation, early embryonic asymmetries and axis patterning in the mouse. Development. 136(5), 701-713. [Abstract]

2008

   
  • Furtado, M., Solloway, M., Jones, V., Costa, M., Biben, C., Wolstein, O., Preis, J., Sparrow, D., Saga, Y., Dunwoodie, S., Robertson, E., Tam, P., Harvey, R. (2008), BMP/SMAD1 signaling sets a threshold for the left/right pathway in lateral plate mesoderm and limits availability of SMAD4. Genes & development. 22(21), 3037-3049. [Abstract]
  • Mihelec, M., St Heaps, L., Flaherty, M., Billson, F., Rudduck, C., Tam, P., Grigg, J., Peters, G., Jamieson, R. (2008), Chromosomal rearrangements and novel genes in disorders of eye development, cataract and glaucoma. Twin Research and Human Genetics. 11(4), 412-421. [Abstract]
  • Franklin, V., Khoo, P., Bildsoe, H., Wong, N., Lewis, S., Tam, P. (2008), Regionalisation of the endoderm progenitors and morphogenesis of the gut portals of the mouse embryo. Mechanisms of Development. 125(7), 587-600. [Abstract]
  • Kondo, M., Gray, L., Pelka, G., Christodoulou, J., Tam, P., Hannan, A. (2008), Environmental enrichment ameliorates a motor coordination deficit in a mouse model of Rett syndrome--Mecp2 gene dosage effects and BDNF expression. The European journal of neuroscience. 27(12), 3342-50. [Abstract]
  • Lewis, S., Khoo, P., De Young, R., Steiner, K., Wilcock, C., Mukhopadhyay, M., Westphal, H., Jamieson, R., Robb, L., Tam, P. (2008), Dkk1 and Wnt3 interact to control head morphogenesis in the mouse. Development (Cambridge). 135(10), 1791-1801. [Abstract]
  • Gabriel, A., Khoo, P., Wong, N., Paul, A., Patrick, P. (2008), Cell grafting and labeling in postimplantation mouse embryos. Methods in Molecular Biology. 461(0), 47-70. [Abstract]
  • Watson, C., Trainor, P., Radziewic, T., Pelka, G., Zhou, S., Parameswaran, M., Quinlan, G., Gordon, M., Sturm, K., Tam, P. (2008), Application of lacZ Transgenic Mice to Cell Lineage Studies. Methods in Molecular Biology. 461, 149-164. [Abstract]

2007

   
  • Fossat, N., Pfister, S., Tam, P. (2007), A transcriptome landscape of mouse embryogenesis. Developmental Cell. 13(6), 761-762. [Abstract]
  • Jamieson, R., Farrar, N., Stewart, K., Perveen, R., Mihelec, M., Carette, M., Grigg, J., McAvoy, J., Lovicu, F., Tam, P., Scambler, P., Lloyd, I., Donnai, D., Black, G. (2007), Characterization of a familial t(16;22) balanced translocation associated with congenital cataract leads to identification of a novel gene, TMEM114, expressed in the lens and disrupted by the translocation. Human mutation. 28(10), 968-977. [Abstract]
  • Tam, P., Lovell-Badge, R. (2007), Anne McLaren 1927-2007. Cell. 130(2), 201-213. [Abstract]
  • Tam, P., Loebel, D. (2007), Gene function in mouse embryogenesis: get set for gastrulation. Nature reviews. Genetics. 8(5), 368-381. [Abstract]
  • Pfister, S., Steiner, K., Tam, P. (2007), Gene expression pattern and progression of embryogenesis in the immediate post-implantation period of mouse development. Gene expression patterns : GEP. 7(5), 558-5573. [Abstract]
  • Lewis, S., Khoo, P., Andrea De Young, R., Bildsoe, H., Wakamiya, M., Behringer, R., Mukhopadhyay, M., Westphal, H., Tam, P. (2007), Genetic interaction of Gsc and Dkk1 in head morphogenesis of the mouse. Mechanisms of Development. 124(2), 157-165. [Abstract]
  • Khoo, P., Franklin, V., Tam, P. (2007), Fate-Mapping Technique: Targeted Whole-Embryo Electroporation of DNA Constructs into the Germ Layers of Mouse Embryos 7-7.5 Days Post-coitum. CSH protocols. 2007, pdb.prot4893. [Abstract]
  • Bildsoe, H., Franklin, V., Tam, P. (2007), Fate-mapping technique: using carbocyanine dyes for vital labeling of cells in gastrula-stage mouse embryos cultured in vitro. CSH protocols. 2007, pdb.prot4915. [Abstract]
  • Tam, P., Khoo, P., Lewis, S., Bildsoe, H., Wong, N., Tsang, T., Gad, J., Robb, L. (2007), Sequential allocation and global pattern of movement of the definitive endoderm in the mouse embryo during gastrulation. Development (Cambridge, England). 134(2), 251-260. [Abstract]
  • Franklin, V., Bildsoe, H., Tam, P. (2007), Fate-Mapping Technique: Grafting Fluorescent Cells into Gastrula-Stage Mouse Embryos at 7-7.5 Days Post-coitum. CSH protocols. 2007, pdb.prot4892. [Abstract]