Publications list for Associate Professor Sarah Hilmer

2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008

2014

   
  • Gnjidic, D., Le Couteur, D., Hilmer, S., Cumming, R., Blyth, F., Naganathan, V., Waite, L., Handelsman, D., Simon Bell, J. (2014), Sedative load and functional outcomes in community-dwelling older Australian men: the CHAMP study. Fundamental and Clinical Pharmacology. 28(1), 10-19. [Abstract]

2013

   
  • Johnston, C., Kirkpatrick, C., McLachlan, A., Hilmer, S. (2013), Physiologically Based Pharmacokinetic Modeling at the Extremes of Age. Clinical Pharmacology and Therapeutics. , 148. [Abstract]
  • Gnjidic, D., Wilson, N., Hilmer, S. (2013), Understanding drug effects in older people: the role of pharmacology. JAMA Internal Medicine. , 1930. [Abstract]
  • Narayan, S., Hilmer, S., Horsburgh, S., Nishtala, P. (2013), Anticholinergic component of the drug burden index and the anticholinergic drug scale as measures of anticholinergic exposure in older people in new zealand: a population-level study. Drugs & Aging. 30(11), 927-934. [Abstract]
  • McCarthy, R., Hilmer, S. (2013), Teaching Junior Medical Officers safe and effective prescribing. Internal Medicine Journal. , 1250-1253. [Abstract]
  • Gnjidic, D., Simon Bell, J., Hilmer, S. (2013), Re-evaluating psychotropic drug use across care settings. Journal of the American Geriatrics Society. , 1640-1641. [Abstract]
  • Ilomaki, J., Gnjidic, D., Hilmer, S., Le Couteur, D., Naganathan, V., Cumming, R., Waite, L., Seibel, M., Blyth, F., Handelsman, D., Bell, J. (2013), Psychotropic drug use and alcohol drinking in community-dwelling older Australian men: the CHAMP study. Drug and Alcohol Review. 32(2), 218-222. [Abstract]
  • Gnjidic, D., Le Couteur, D., Hilmer, S. (2013), Discontinuation of statins in routine care settings. Annals of Internal Medicine. , 73-74. [Abstract]
  • Bennett, A., Gnjidic, D., Hilmer, S. (2013), Medication exposure may confound the association between dietary intake and frailty. The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences. , 1440. [Abstract]
  • Best, O., Gnjidic, D., Hilmer, S., Naganathan, V., McLachlan, A. (2013), Investigating polypharmacy and drug burden index in hospitalised older people. Internal Medicine Journal. 43(8), 912-918. [Abstract]
  • Gnjidic, D., Hilmer, S., Le Couteur, D. (2013), Optimal cutoff of polypharmacy and outcomes - reply. Journal of Clinical Epidemiology. 66(4), 465-466. [Abstract]
  • Nguyen, T., Hilmer, S., Cumming, R. (2013), Review of epidemiology and management of atrial fibrillation in developing countries. International Journal of Cardiology. 167(6), 2412-2420. [Abstract]
  • Hilmer, S., Gnjidic, D. (2013), Rethinking psychotropics in nursing homes. The Medical Journal of Australia. 198(2), 77. [Abstract]
  • Gnjidic, D., Hilmer, S. (2013), Discontinuation of risperidone in Alzheimer's disease. The New England Journal of Medicine. , 186. [Abstract]
  • Hilmer, S., Gnjidic, D. (2013), Letter: Rethinking psychotropics in nursing homes. The Medical Journal of Australia. , 99. [Abstract]
  • Gnjidic, D., Le Couteur, D., Blyth, F., Travison, T., Rogers, K., Naganathan, V., Cumming, R., Waite, L., Seibel, M., Handelsman, D., McLachlan, A., Hilmer, S. (2013), Statin use and clinical outcomes in older men: a prospective population-based study. BMJ Open. 3(3), 1-10. [Abstract]
  • Hilmer, S., Gnjidic, D. (2013), Statins in older adults. Australian Prescriber. 36(3), 79-82.
  • Gnjidic, D., Le Couteur, D., Pearson, S., McLachlan, A., Viney, R., Hilmer, S., Blyth, F., Joshy, G., Banks, E. (2013), High risk prescribing in older adults: prevalence, clinical and economic implications and potential for intervention at the population level. BMC Public Health. 13, 115. [Abstract]

2012

   
  • Hilmer, S., Gnjidic, D., Le Couteur, D. (2012), Thinking through the medication list - appropriate prescribing and deprescribing in robust and frail older patients. Australian Family Physician. 41(12), 924-928. [Abstract]
  • Lowry, E., Woodman, R., Soiza, R., Hilmer, S., Mangoni, A. (2012), Drug burden index, physical function, and adverse outcomes in older hospitalized patients. Journal of Clinical Pharmacology. 52(10), 1584-1591. [Abstract]
  • Mitchell, S., Huizer-Pajkos, A., Cogger, V., McLachlan, A., Le Couteur, D., Jones, B., de Cabo, R., Hilmer, S. (2012), The Influence of Old Age and Poloxamer-407 on the Hepatic Disposition of Diazepam in the Isolated Perfused Rat Liver. Pharmacology. 90(5-6), 233-241. [Abstract]
  • Gnjidic, D., Hilmer, S., Blyth, F., Naganathan, V., Waite, L., Seibel, M., McLachlan, A., Cumming, R., Handelsman, D., Le Couteur, D. (2012), Polypharmacy cutoff and outcomes: five or more medicines were used to identify community-dwelling older men at risk of different adverse outcomes. Journal of Clinical Epidemiology. 65(9), 989-995. [Abstract]
  • Kane, A., Mitchell, S., Carroll, P., Matthews, S., Hilmer, S. (2012), Characteristics of older and younger patients with suspected paracetamol toxicity. Australasian Journal on Ageing. 31(3), 190-193. [Abstract]
  • Tannenbaum, C., Paquette, A., Hilmer, S., Holroyd-Leduc, J., Carnahan, R. (2012), A systematic review of amnestic and non-amnestic mild cognitive impairment induced by anticholinergic, antihistamine, GABAergic and opioid drugs. Drugs & Aging. 29(8), 639-658. [Abstract]
  • Gnjidic, D., Le Couteur, D., Hilmer, S. (2012), Off-Label Use of Medicines: Time for Action. Clinical Pharmacology and Therapeutics. 92(2), 157. [Abstract]
  • Lönnroos, E., Gnjidic, D., Hilmer, S., Bell, J., Kautiainen, H., Sulkava, R., Hartikainen, S. (2012), Drug Burden Index and hospitalization among community-dwelling older people. Drugs & Aging. 29(5), 395-404. [Abstract]
  • Gnjidic, D., Le Couteur, D., Kouladjian, L., Hilmer, S. (2012), Deprescribing trials: methods to reduce polypharmacy and the impact on prescribing and clinical outcomes. Clinics in Geriatric Medicine. 28(2), 237-253. [Abstract]
  • Gnjidic, D., Le Couteur, D., Naganathan, V., Cumming, R., Creasey, H., Waite, L., Sharma, A., Blyth, F., Hilmer, S. (2012), Effects of drug burden index on cognitive function in older men. Journal of Clinical Psychopharmacology. 32(2), 273-277. [Abstract]
  • Fraser, R., Cogger, V., Dobbs, B., Jamieson, H., Warren, A., Hilmer, S., Le Couteur, D. (2012), The liver sieve and atherosclerosis. Pathology. 44(3), 181-186. [Abstract]
  • Gnjidic, D., Hilmer, S., Blyth, F., Naganathan, V., Cumming, R., Handelsman, D., McLachlan, A., Abernethy, D., Banks, E., Le Couteur, D. (2012), High-risk prescribing and incidence of frailty among older community-dwelling men. Clinical pharmacology and therapeutics. 91(3), 521-528. [Abstract]
  • Gnjidic, D., Hilmer, S. (2012), Emergency hospitalizations for adverse drug events. New England Journal of Medicine. 366(9), 859. [Abstract]
  • McCarthy, R., Ogle, S., Finnegan, T., Hilmer, S. (2012), Which Aged Care inpatients are potentially suitable for community-based acute care?. Australasian Journal on Ageing. 31(1), 56-59. [Abstract]
  • Gnjidic, D., Hilmer, S. (2012), Potential contribution of medications to frailty. Journal of the American Geriatrics Society. 60(2), 401. [Abstract]
  • Wilson, N., Hilmer, S., March, L., Chen, J., Gnjidic, D., Mason, R., Cameron, I., Sambrook, P. (2012), Associations between drug burden index and mortality in older people in residential aged care facilities. Drugs & Aging. 29(2), 157-165. [Abstract]
  • Mitchell, S., Hilmer, S., Kirkpatrick, C., Hansen, R., Williamson, D., Singh, N., Finnegan, T., Allen, B., Diamond, T., Diwan, A., Lloyd, B., Smith, E., Fiatarone Singh, M. (2012), Estimation of lean body weight in older women with hip fracture. Journal of Nutrition, Health & Aging. 16(2), 188-192. [Abstract]
  • Hilmer, S., Gnjidic, D., Abernethy, D. (2012), Pharmacoepidemiology in the Postmarketing Assessment of the Safety and Efficacy of Drugs in Older Adults. Journals of Gerontology. Series A: Biological Sciences & Medical Sciences. 67(2), 181-188. [Abstract]
  • Gnjidic, D., Bell, J., Hilmer, S., Lönnroos, E., Sulkava, R., Hartikainen, S. (2012), Drug Burden Index associated with function in community-dwelling older people in Finland: A cross-sectional study. Annals of Medicine. 44(5), 458-467. [Abstract]
  • Gnjidic, D., Hilmer, S., Le Couteur, D. (2012), High-risk prescribing in older people: More harm than good?. Aging Health. 8, 325-327.
  • Bell, J., Le Couteur, D., McLachlan, A., Chen, T., Moles, R., Basger, B., Hilmer, S. (2012), Improving medicine selection for older people - Do we need an Australian classification for inappropriate medicines use?. Australian Family Physician. 41(1-2), 9-10. [Abstract]

2011

   
  • Wilson, N., Gnjidic, D., March, L., Sambrook, P., Hilmer, S. (2011), Use of PPIs Are Not Associated With Mortality in Institutionalized Older People. Archives of Internal Medicine. 171(9), 866. [Abstract]
  • Gnjidic, D., Le Couteur, D., Abernethy, D., Hilmer, S. (2011), Reducing drugs in older adults is more. Archives of Internal Medicine. 171(9), 868-869. [Abstract]
  • Wilson, N., Hilmer, S., March, L., Cameron, I., Lord, S., Seibel, M., Mason, R., Chen, J., Cumming, R., Sambrook, P. (2011), Associations Between Drug Burden Index and Falls in Older People in Residential Aged Care. Journal of the American Geriatrics Society. 59(5), 875-880. [Abstract]
  • Mitchell, S., Huizer-Pajkos, A., Cogger, V., McLachlan, A., Le Couteur, D., Jones, B., de Cabo, R., Hilmer, S. (2011), Age-related pseudocapillarization of the liver sinusoidal endothelium impairs the hepatic clearance of acetaminophen in rats. Journals of Gerontology. Series A: Biological Sciences & Medical Sciences. 66(4), 400-408. [Abstract]
  • McLachlan, A., Bath, S., Naganathan, V., Hilmer, S., Le Couteur, D., Gibson, S., Blyth, F. (2011), Clinical pharmacology of analgesic medicines in older people: impact of frailty and cognitive impairment. British Journal of Clinical Pharmacology. 71(3), 351-364. [Abstract]
  • Gnjidic, D., Le Couteur, D., Abernethy, D., Hilmer, S. (2011), Drug Burden Index and Beers Criteria: Impact on Functional Outcomes in Older People Living in Self-Care Retirement Villages. Journal of Clinical Pharmacology. 52(2), 258-265. [Abstract]
  • Hilmer, S., Tran, K., Rubie, P., Wright, J., Gnjidic, D., Mitchell, S., Matthews, S., Carroll, P. (2011), Gentamicin pharmacokinetics in old age and frailty. British Journal of Clinical Pharmacology. 71(2), 224-231. [Abstract]
  • Wilson, N., Hilmer, S., March, L., Cameron, I., Lord, S., Mason, R., Sambrook, P. (2011), Physical functioning measures and risk of falling in older people living in residential aged care facilities. Therapeutic Advances in Musculoskeletal Disease. 3(1), 9-15.
  • Mitchell, S., Kane, A., Hilmer, S. (2011), Age-related changes in the hepatic pharmacology and toxicology of paracetamol. Current Gerontology and Geriatrics Research. 2011, 624156. [Abstract]
  • Hardy, J., Hilmer, S. (2011), Deprescribing in the last year of life. Journal of Pharmacy Practice and Research. 41(2), 146-151.
  • Wilson, N., Gnjidic, D., Hilmer, S. (2011), Safe Drug Use in Residential Aged Care Facilities. Geriatric Medicine in General Practice. 9, 6-8.
  • Mitchell, S., Huizer-Pajkos, A., Cogger, V., McLachlan, A., Le Couteur, D., Hilmer, S. (2011), Poloxamer 407 increases the recovery of paracetamol in the isolated perfused rat liver. Journal of pharmaceutical sciences. 100(1), 334-40. [Abstract]
  • Sittironnarit, G., Ames, D., Bush, A., Faux, N., Flicker, L., Foster, J., Hilmer, S., Lautenschlager, N., Maruff, P., Masters, C., Martins, R., Rowe, C., Szoeke, C., Ellis, K. (2011), Effects of anticholinergic drugs on cognitive function in older Australians: results from the AIBL study. Dementia and Geriatric Cognitive Disorders. 31(3), 173-178. [Abstract]
  • Johnston, C., Carroll, P., Matthews, S., Mitchell, S., Hilmer, S. (2011), 'You look like a 240 mg': Gentamicin dosing at a Sydney hospital. Journal of Pharmacy Practice and Research. 41(4), 275-277.
  • Cogger, V., Hilmer, S., Svistounov, D. (2011), Mechanisms and implications of age-related changes in the liver. Current Gerontology and Geriatrics Research. 2011, 150364. [Abstract]

2010

   
  • Gnjidic, D., Le Couteur, D., Abernethy, D., Hilmer, S. (2010), A Pilot Randomized Clinical Trial Utilizing the Drug Burden Index to Reduce Exposure to Anticholinergic and Sedative Medications in Older People (November). The Annals of pharmacotherapy. 44(11), 1725-32. [Abstract]
  • Joester, J., Vogler, C., Chang, K., Hilmer, S. (2010), Hypnosedative use and predictors of successful withdrawal in new patients attending a falls clinic: a retrospective, cohort study. Drugs & Aging. 27(11), 915-924. [Abstract]
  • Cheluvappa, R., Denning, G., Lau, G., Grimm, M., Hilmer, S., Le Couteur, D. (2010), Pathogenesis of the hyperlipidemia of Gram-negative bacterial sepsis may involve pathomorphological changes in liver sinusoidal endothelial cells. International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases. 14(10), e857-67. [Abstract]
  • Broadfoot, A., Ogle, S., Foster, K., Thanh, H., Hilmer, S. (2010), Teaching Geriatric Medicine in Vietnam: Introduction of an interactive learning module for medical students. Australasian Journal on Ageing. 29(3), 135-136. [Abstract]
  • Perera, V., Hilmer, S., McLachlan, A. (2010), Frailty should be assessed using validated scales. Drugs & Aging. , 687. [Abstract]
  • Wilson, N., Hilmer, S., March, L., Cameron, I., Lord, S., Seibel, M., Sambrook, P. (2010), Associations between drug burden index and physical function in older people in residential aged care facilities. Age and ageing. 39(4), 503-7. [Abstract]
  • Castelino, R., Hilmer, S., Bajorek, B., Nishtala, P., Chen, T. (2010), Drug Burden Index and potentially inappropriate medications in community-dwelling older people: the impact of Home Medicines Review. Drugs & aging. 27(2), 135-48. [Abstract]
  • Mitchell, S., Kirkpatrick, C., Le Couteur, D., Naganathan, V., Sambrook, P., Seibel, M., Blyth, F., Waite, L., Handelsman, D., Cumming, R., Hilmer, S. (2010), Estimation of lean body weight in older community-dwelling men. British Journal of Clinical Pharmacology. 69(2), 118-127. [Abstract]
  • Hilmer, S., Gnjidic, D. (2010), Adverse drug reactions in older people. Geriatric Medicine in General Practice. 4, 32-33.
  • Mitchell, S., Hilmer, S. (2010), Drug induced liver injury in older adults. Therapeutic Advances in Drug Safety. 1(2), 65-77.
  • McLachlan, A., Hilmer, S., Le Couteur, D. (2010), Dosing Errors: Age-Related Changes in Pharmacokinetics. In: Medication Management in Older Adults. (pp.127-125).United States: Springer Science + Business Media B.V..
  • Murnion, B., Gnjidic, D., Hilmer, S. (2010), Prescription and Administration of Opioids to Hospital In-patients, and Barriers to Effective Use. Pain Medicine. 11(1), 58-66. [Abstract]
  • Mitchell, S., Hilmer, S., Murnion, B., Matthews, S. (2010), Hepatotoxicity of therapeutic short-course paracetamol in hospital inpatients: impact of ageing and frailty. Journal of Clinical Pharmacy and Therapeutics. 0, doi:10.1111/j.1365-2710.2010.01193.
  • Wilson, N., March, L., Sambrook, P., Hilmer, S. (2010), Medication Safety in Residential Aged Care: a Perspective. Therapeutic Advances in Drug Safety. 1(1), 11-20.
  • Gnjidic, D., Hilmer, S. (2010), Multiple medications and assessment of inappropriate medication use in older adults. Geriatric Medicine in General Practice. 6, 24-25.
  • Gnjidic, D., Hilmer, S. (2010), Use of potentially inappropriate medications in the care of frail older people. Aging Health. 6(6), 705-716.

2009

   
  • Hilmer, S., Mager, D., Simonsick, E., Ling, S., Windham, B., Harris, T., Shorr, R., Bauer, D., Abernethy, D. (2009), Drug burden index score and functional decline in older people. The American journal of medicine. 122(12), 1142-1149.e2. [Abstract]
  • Hilmer, S., Perera, V., Mitchell, S., Murnion, B., Dent, J., Bajorek, B., Matthews, S., Rolfson, D. (2009), The assessment of frailty in older people in acute care. Australasian Journal on Ageing. 28(4), 182-188. [Abstract]
  • Gnjidic, D., Cumming, R., Le Couteur, D., Handelsman, D., Naganathan, V., Abernethy, D., Hilmer, S. (2009), Drug Burden Index and physical function in older Australian men. British Journal of Clinical Pharmacology. 68(1), 97-105. [Abstract]
  • Hilmer, S., Seale, J., Le Couteur, D., Crampton, R., Liddle, C. (2009), Do medical courses adequately prepare interns for safe and effective prescribing in New South Wales public hospitals?. Internal medicine journal. 39(7), 428-34. [Abstract]
  • McLachlan, A., Hilmer, S., Le Couteur, D. (2009), Variability in response to medicines in older people: phenotypic and genotypic factors. Clinical Pharmacology and Therapeutics. 85(4), 431-433. [Abstract]
  • Hanlon, J., Boudreau, R., Roumani, Y., Newman, A., Ruby, C., Wright, R., Hilmer, S., Shorr, R., Bauer, D., Simonsick, E., Studenski, S. (2009), Number and Dosage of Central Nervous System Medications on Recurrent Falls in Community Elders: The Health, Aging and Body Composition Study. The journals of gerontology. Series A, Biological sciences and medical sciences. 64(4), 492-8. [Abstract]
  • Perera, V., Bajorek, B., Matthews, S., Hilmer, S. (2009), The impact of frailty on the utilisation of antithrombotic therapy in older patients with atrial fibrillation. Age and ageing. 38(2), 156-62. [Abstract]
  • Wright, R., Roumani, Y., Boudreau, R., Newman, A., Ruby, C., Studenski, S., Shorr, R., Bauer, D., Simonsick, E., Hilmer, S., Hanlon, J. (2009), Effect of central nervous system medication use on decline in cognition in community-dwelling older adults: findings from the Health, Aging And Body Composition Study. Journal of the American Geriatrics Society. 57(2), 243-250. [Abstract]
  • Boudreau, R., Hanlon, J., Roumani, Y., Studenski, S., Ruby, C., Wright, R., Hilmer, S., Shorr, R., Bauer, D., Simonsick, E., Newman, A. (2009), Central nervous system medication use and incident mobility limitation in community elders: the health, aging, and body composition study. Pharmacoepidemiology and Drug Safety. 18(10), 916-922. [Abstract]
  • Nishtala, P., Hilmer, S., McLachlan, A., Hannan, P., Chen, T. (2009), Impact of residential medication management reviews on drug burden index in aged-care homes: a retrospective analysis. Drugs & Aging. 26(8), 677-686. [Abstract]
  • Hilmer, S., Ford, G. (2009), General Principals of Pharmacology. In: Hazzard’s Principles of Geriatric Medicine and Gerontology 6th ed. (pp.103-122).United States: McGraw-Hill Company.
  • Mitchell, S., Hilmer, S., McLachlan, A. (2009), Clinical pharmacology of analgesics in old age and frailty. Reviews in Clinical Gerontology. 19(0), 103-118.
  • Hilmer, S., Gnjidic, D. (2009), The effects of polypharmacy in older adults. Clinical pharmacology and therapeutics. 85(1), 86-8. [Abstract]
  • Mitchell, S., Murnion, B., Matthews, S., Hilmer, S. (2009), Compliance with Paracetamol Prescribing Policies at a Sydney Hospital. Journal of Pharmacy Practice and Research. 39(2), 122-127.
  • Cheluvappa, R., Denning, G., Lau, G., Grimm, M., Hilmer, S., Le Couteur, D. (2009), Pseudomonas aeruginosa and the hyperlipidaemia of sepsis. Pathology. 41(7), 615-621. [Abstract]
  • Mitchell, S., Hilmer, S. (2009), What dose? Pharmacokinetic and pharmacodynamic changes in ageing and frailty. Geriatric Medicine in General Practice. 3, 30-31.

2008

   
  • Cheluvappa, R., Cogger, V., Kwun, S., O'Reilly, J., Le Couteur, D., Hilmer, S. (2008), Liver sinusoidal endothelial cells and acute non-oxidative hepatic injury induced by Pseudomonas aeruginosa pyocyanin. International Journal of Experimental Pathology. 89(6), 410-418. [Abstract]
  • Gnjidic, D., Murnion, B., Hilmer, S. (2008), Age and opioid analgesia in an acute hospital population. Age and ageing. 37(6), 699-702. [Abstract]
  • Hilmer, S. (2008), ADME-tox issues for the elderly. Expert Opinion on Drug Metabolism & Toxicology. 4(10), 1321-1331. [Abstract]
  • Hilmer, S., Abernethy, D. (2008), Measures of drug toxicity in older adults. Archives of Internal Medicine. 168(17), 1930-1931. [Abstract]
  • Warren, A., Chaberek, S., Ostrowski, K., Cogger, V., Hilmer, S., McCuskey, R., Fraser, R., Le Couteur, D. (2008), Effects of old age on vascular complexity and dispersion of the hepatic sinusoidal network. Microcirculation. 15(3), 191-202. [Abstract]
  • Cao, Y., Mager, D., Simonsick, E., Hilmer, S., Ling, S., Windham, B., Crentsil, V., Yasar, S., Fried, L., Abernethy, D. (2008), Physical and cognitive performance and burden of anticholinergics, sedatives, and ACE inhibitors in older women. Clinical Pharmacology and Therapeutics. 83(3), 422-429. [Abstract]
  • Cheluvappa, R., Shimmon, R., Dawson, M., Hilmer, S., Le Couteur, D. (2008), Reactions of Pseudomonas aeruginosa pyocyanin with reduced glutathione. Acta biochimica Polonica. 55(3), 571-80. [Abstract]