Publications list for Associate Professor Vitali Sintchenko

2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008


  • Ellis, S., Kalinowski, D., Leotta, L., Huang, M., Jelfs, P., Sintchenko, V., Richardson, D., Triccas, J. (2014), Potent Anti-Mycobacterial Activity of the Pyridoxal Isonicotinoyl Hydrazone Analogue, 2-Pyridylcarboxaldehyde Isonicotinoyl Hydrazone: A Lipophilic Transport Vehicle for Isonicotinic Acid Hydrazide. Molecular Pharmacology. 85(2), 269-278. [Abstract]


  • O'Sullivan, M., Sintchenko, V., Gilbert, G. (2013), Quantitative Estimation of MRSA Strain-Typing System Stability Using Kaplan-Meier Survival Analysis. Journal of Clinical Microbiology. 51(1), 112-116. [Abstract]
  • McIntyre, P., Sintchenko, V. (2013), The "how" of PCR testing for Bordetella pertussis depends on the "why". Clinical Infectious Diseases. 56(3), 332-334. [Abstract]
  • Marks, G., Christensen, A., Sintchenko, V., Lowbridge, C. (2013), Tuberculosis: an old world disease providing new world challenges in NSW. New South Wales Public Health Bulletin. 24(1), 22-23. [Abstract]
  • Gilbert, G., Sintchenko, V. (2013), The use of mycobacterial interspersed repetitive unit typing and whole genome sequencing to inform tuberculosis prevention and control activities. New South Wales Public Health Bulletin. 24(1), 10-14. [Abstract]
  • O Sullivan, M., Sintchenko, V., Gilbert, G. (2013), Software for selecting the most informative sets of genomic loci for multi-target microbial typing. BMC Bioinformatics. 14(1), 148. [Abstract]
  • Stephens, N., Vogelnest, L., Lowbridge, C., Christensen, A., Marks, G., Sintchenko, V., McAnulty, J. (2013), Transmission of Mycobacterium tuberculosis from an Asian elephant (Elephas maximus) to a chimpanzee (Pan troglodytes) and humans in an Australian zoo. Epidemiology and Infection. 141(7), 1488-1497. [Abstract]
  • Sadsad, R., Sintchenko, V., McDonnell, G., Gilbert, G. (2013), Effectiveness of Hospital-Wide Methicillin-ResistantStaphylococcus aureus (MRSA) Infection Control Policies Differs by Ward Specialty. PloS One. 8(12), e83099. [Abstract]
  • Le Hello, S., Bekhit, A., Granier, S., Barua, H., Beutlich, J., Zajac, M., Munch, S., Sintchenko, V., Bouchrif, B., Fashae, K., Pinsard, J., Sontag, L., Fabre, L., Garnier, M., Guibert, V., Howard, P., Hendriksen, R., Christensen, J., Biswas, P., Cloeckaert, A., Rabsch, W., Wasyl, D., Doublet, B., Weill, F. (2013), The global establishment of a highly-fluoroquinolone resistant Salmonella enterica serotype Kentucky ST198 strain. Frontiers in Microbiology. 4, 395. [Abstract]


  • Lau, A., Sintchenko, V., Crimmins, J., Magrabi, F., Gallego, B., Coiera, E. (2012), Impact of a web-based personally controlled health management system on influenza vaccination and health services utilization rates: a randomized controlled trial. Journal of the American Medical Informatics Association. 19(5), 719-727. [Abstract]
  • Jackson, J., McGregor, A., Cooley, L., Ng, J., Brown, M., Ong, C., Darcy, C., Sintchenko, V. (2012), Francisella tularensis subspecies holarctica, Tasmania, Australia, 2011. Emerging Infectious Diseases. 18(9), 1484-1486. [Abstract]
  • O'Sullivan, M., Zhou, F., Sintchenko, V., Gilbert, G. (2012), Prospective genotyping of hospital-acquired MRSA using a novel, highly discriminatory binary typing system. Journal of Clinical Microbiology. 50(11), 3513-3519. [Abstract]
  • Kong, Q., Xiao, M., Kong, F., Yuen, M., Brown, M., Ng, J., Ahuja, V., Hicks, L., Shen, L., Xu, H., Sintchenko, V., Gilbert, G., James, G. (2012), Assignment of recA reference sequence types for enhanced identification of the Burkholderia cepacia complex. Pathology. 44(4), 373-375. [Abstract]
  • Octavia, S., Sintchenko, V., Gilbert, G., Lawrence, A., Keil, A., Hogg, G., Lan, R. (2012), Newly emerging clones of Bordetella pertussis carrying prn2 and ptxP3 alleles implicated in Australian pertussis epidemic in 2008-2010. The Journal of Infectious Diseases. 205(8), 1220-1224. [Abstract]
  • Lam, C., Octavia, S., Bahrame, Z., Sintchenko, V., Gilbert, G., Lan, R. (2012), Selection and emergence of pertussis toxin promoter ptxP3 allele in the evolution of Bordetella pertussis. Infection, Genetics and Evolution. 12(2), 492-495. [Abstract]
  • Pang, S., Octavia, S., Reeves, P., Wang, Q., Gilbert, G., Sintchenko, V., Lan, R. (2012), Genetic relationships of phage types and single nucleotide polymorphism typing of Salmonella enterica serovar Typhimurium. Journal of Clinical Microbiology. 50(3), 727-734. [Abstract]
  • Sintchenko, V., Wang, Q., Howard, P., Ha, C., Kardamanidis, K., Musto, J., Gilbert, G. (2012), Improving resolution of public health surveillance for human Salmonella enterica serovar Typhimurium infection: 3 years of prospective multiple-locus variable-number tandem-repeat analysis (MLVA). BMC Infectious Diseases. 12, 78. [Abstract]
  • Helal, M., Kong, F., Chen, S., Zhou, F., Dwyer, D., Potter, J., Sintchenko, V. (2012), Linear normalised hash function for clustering gene sequences and identifying reference sequences from multiple sequence alignments. Microbial Informatics and Experimentation. 2(1), 2. [Abstract]
  • Lau, A., Sintchenko, V., Crimmins, J., Magrabi, F., Gallego, B., Coiera, E. (2012), Protocol for a randomised controlled trial examining the impact of a web-based personally controlled health management system on the uptake of influenza vaccination rates. BMC Health Services Research. 12, 86. [Abstract]


  • Lin, F., Lan, R., Sintchenko, V., Gilbert, G., Kong, F., Coiera, E. (2011), Computational Bacterial Genome-Wide Analysis of Phylogenetic Profiles Reveals Potential Virulence Genes of Streptococcus agalactiae. PLoS One. 6(4), e17964. [Abstract]
  • Octavia, S., Maharjan, R., Sintchenko, V., Stevenson, G., Reeves, P., Gilbert, G., Lan, R. (2011), Insight into evolution of Bordetella pertussis from comparative genomic analysis: evidence of vaccine-driven selection. Molecular Biology and Evolution. 28(1), 707-715. [Abstract]
  • Helal, M., Kong, F., Chen, S., Bain, M., Christen, R., Sintchenko, V. (2011), Defining Reference Sequences for Nocardia Species by Similarity and Clustering Analyses of 16S rRNA Gene Sequence Data. PLoS One. 6(6), e19517. [Abstract]
  • Watts, M., Taylor, P., Sintchenko, V., Whelan, C., Farnsworth, R., Jones, P., Jelfs, P., Carr, D., Goldberg, H. (2011), Editor's choice: Implications of isoniazid resistance in Mycobacterium bovis Bacillus Calmette-Guérin used for immunotherapy in bladder cancer. Clinical Infectious Diseases. 52(1), 86-88. [Abstract]
  • O'Sullivan, M., Zhou, F., Sintchenko, V., Kong, F., Gilbert, G. (2011), Multiplex PCR and Reverse Line Blot Hybridization Assay (mPCR/RLB). Journal of Visualized Experiments. 6(54), pii: 2781. [Abstract]
  • Sintchenko, V., Coiera, E. (2011), Translational web robots for pathogen genome analysis. Microbial Informatics and Experimentation. 1(1), 10. [Abstract]
  • Wang, T., Kong, F., Chen, S., Xiao, M., Sorrell, T., Wang, X., Wang, S., Sintchenko, V. (2011), Improved identification of Gordonia, Rhodococcus and Tsukamurella species by 5'-end 16S rRNA gene sequencing. Pathology. 43(1), 58-63. [Abstract]


  • Kong, F., Wang, H., Zhang, E., Sintchenko, V., Xiao, M., Sorrell, T., Chen, X., Chen, S. (2010), SecA1 Gene Sequence Polymorphisms for Species Identification of Nocardia and Recognition of Intraspecies Genetic Diversity. Journal of clinical microbiology. 48(11), 3928-34. [Abstract]
  • Liu, Y., Kong, F., Xiao, M., Wang, Q., O'Sullivan, M., Sintchenko, V., Ma, L., Gilbert, G. (2010), Unexpected diversity of staphylococcal cassette chromosome mec (SCCmec) type IV in methicillin-resistant Staphylococcus aureus. Journal of clinical microbiology. 48(10), 3628-34. [Abstract]
  • O'Sullivan, M., Kong, F., Sintchenko, V., Gilbert, G. (2010), Rapid Identification of MRSA Transmission in Hospitals using Phage-Derived ORF Typing enhanced by Multiplex PCR and Reverse Line Blot Assay. Journal of clinical microbiology. 48(8), 2741-8. [Abstract]
  • Wang, X., Xiao, M., Kong, F., Sintchenko, V., Wang, H., Wang, B., Lian, S., Sorrell, T., Chen, S. (2010), Reverse line blot hybridization and DNA sequencing studies of the 16S-23S rRNA gene intergenic spacer regions of five emerging pathogenic Nocardia species. Journal of Medical Microbiology. 59(Pt 5), 548-555. [Abstract]
  • Couldwell, D., Gidding, H., Freedman, E., McKechnie, M., Biggs, K., Sintchenko, V., Gilbert, G. (2010), Ureaplasma urealyticum is significantly associated with non-gonococcal urethritis in heterosexual Sydney men. International Journal of STD & AIDS. 21(5), 337-341. [Abstract]
  • Gallego, B., Sintchenko, V., Jelfs, P., Coiera, E., Gilbert, G. (2010), Three-year longitudinal study of genotypes of Mycobacterium tuberculosis in a low prevalence population. Pathology. 42(3), 267-272. [Abstract]
  • Xiao, M., Kong, F., Sorrell, T., Cao, Y., Lee, O., Liu, Y., Sintchenko, V., Chen, S. (2010), Identification of Pathogenic Nocardia Species by Reverse Line Blot Hybridization Targeting the 16S rDNA and 16S-23S rDNA Spacer Regions. Journal of clinical microbiology. 48(2), 503-11. [Abstract]
  • Kurniawan, J., Maharjan, R., Chan, W., Reeves, P., Sintchenko, V., Gilbert, G., Mooi, F., Lan, R. (2010), Bordetella pertussis clones identified by multilocus variable-number tandem-repeat analysis. Emerging infectious diseases. 16(2), 297-300. [Abstract]
  • Sintchenko, V. (2010), Informatics for Infectious Disease Research and Control. In: Infectious Disease Informatics. (pp.1-26).United States: Springer.
  • Potter, S., Sintchenko, V., Enemark, C. (2010), Bug breakfast in the Bulletin: Biosecurity and infectious diseases. New South Wales public health bulletin. 21(5-6), 146-147. [Abstract]
  • Anthony, S., Sintchenko, V., Coiera, E. (2010), Text Mining for Discovery of Host–Pathogen Interactions. In: Infectious disease informatics. (pp.149-165).United States: Springer.
  • Sintchenko, V. (2010), Infectious Disease Informatics. United States: Springer.
  • Sintchenko, V., Anthony, S., Phan, X., Lin, F., Coiera, E. (2010), A PubMed-wide associational study of infectious diseases. PloS One. 5(3), e9535. [Abstract]


  • Lee, A., Jelfs, P., Sintchenko, V., Gilbert, G. (2009), Identification of non-tuberculous mycobacteria: utility of the GenoType Mycobacterium CM/AS assay compared with HPLC and 16S rRNA gene sequencing. Journal of Medical Microbiology. 58(7), 900-904. [Abstract]
  • Chan, W., Maharjan, R., Reeves, P., Sintchenko, V., Gilbert, G., Lan, R. (2009), Rapid and accurate typing of Bordetella pertussis targeting genes encoding acellular vaccine antigens using real time PCR and High Resolution Melt analysis. Journal of microbiological methods. 77(3), 326-329. [Abstract]
  • Sintchenko, V., Gallego, B. (2009), Laboratory-guided detection of disease outbreaks: three generations of surveillance systems. Archives of Pathology & Laboratory Medicine. 133(6), 916-925. [Abstract]
  • Gallego, B., Sintchenko, V., Wang, Q., Hiley, L., Gilbert, G., Coiera, E. (2009), Biosurveillance of emerging biothreats using scalable genotype clustering. Journal of biomedical informatics. 42(1), 66-73. [Abstract]
  • Helal, M., Sintchenko, V. (2009), Dynamic programming algorithms for discovery of antibiotic resistance in microbial genomes. HIC 2009 Proceedings, Handbook of Abstracts & CD ROM: Frontiers of Health Inofrmatics - Redefining Healthcare.
  • Lin, F., Sintchenko, V., Kong, F., Gilbert, G., Coiera, E. (2009), Commonly used molecular epidemiology markers of Streptococcus agalactiae do not appear to predict virulence. Pathology. 41(6), 576-581. [Abstract]
  • Cai, L., Kong, F., Wang, Q., Wang, H., Xiao, M., Sintchenko, V., Gilbert, G. (2009), A new multiplex PCR-based reverse line-blot hybridization (mPCR/RLB) assay for rapid staphylococcal cassette chromosome mec (SCCmec) typing. Journal of Medical Microbiology. 58(8), 1045-1057. [Abstract]
  • van Hal, S., Foo, H., Blyth, C., McPhie, K., Armstrong, P., Sintchenko, V., Dwyer, D. (2009), Influenza outbreak during Sydney World Youth Day 2008: the utility of laboratory testing and case definitions on mass gathering outbreak containment. PloS One. 4(9), e6620. [Abstract]
  • Sintchenko, V., Gallego, B., Chung, G., Coiera, E. (2009), Towards bioinformatics assisted infectious disease control. BMC Bioinformatics. 10(Suppl 2), S10. [Abstract]
  • Kong, F., Chen, S., Chen, X., Sintchenko, V., Halliday, C., Cai, L., Tong, Z., Lee, O., Sorrell, T. (2009), Assignment of Reference 5'-end 16S rDNA Sequences and Species-Specific Sequence Polymorphisms Improves Species Identification of Nocardia. The Open Microbiology Journal. 3(0), 97-105. [Abstract]
  • Cai, L., Kong, F., Jelfs, P., Gilbert, G., Sintchenko, V. (2009), Rolling circle amplification and multiplex allele-specific PCR for rapid detection of katG and inhA gene mutations in Mycobacterium tuberculosis. International Journal of Medical Microbiology. 299(8), 574-581. [Abstract]
  • Coiera, E., Lau, A., Tsafnat, G., Sintchenko, V., Magrabi, F. (2009), The changing nature of clinical decision support systems: a focus on consumers, genomics, public health and decision safety. Yearbook of Medical Informatics. 0(0), 84-95. [Abstract]
  • Lin, F., Coiera, E., Lan, R., Sintchenko, V. (2009), In silico prioritisation of candidate genes for prokaryotic gene function discovery: an application of phylogenetic profiles. BMC Bioinformatics. 10, 86. [Abstract]


  • Sintchenko, V., Coiera, E., Gilbert, G. (2008), Decision support systems for antibiotic prescribing. Current Opinion in Infectious Diseases. 21(6), 573-579. [Abstract]
  • Sintchenko, V., Coiera, E. (2008), Developing decision support systems in clinical bioinformatics. Methods in molecular medicine. 141, 331-351. [Abstract]
  • Sintchenko, V. (2008), The re-emergence of pertussis: implications for diagnosis and surveillance. New South Wales Public Health Bulletin. 19(7-8), 143-145. [Abstract]
  • Maharjan, R., Gu, C., Reeves, P., Sintchenko, V., Gilbert, G., Lan, R. (2008), Genome-wide analysis of single nucleotide polymorphisms in Bordetella pertussis using comparative genomic sequencing. Research in microbiology. 159(0), 602-8. [Abstract]