Publications list for Professor Warwick Britton

2013 | 2012 | 2011 | 2010 | 2009 | 2008


  • Walters, S., Kieckbusch, J., Nagalingam, G., Swain, A., Latham, S., Grau, G., Britton, W., Combes, V., Saunders, B. (2013), Microparticles from Mycobacteria-Infected Macrophages Promote Inflammation and Cellular Migration. Journal of Immunology. 190(2), 669-677. [Abstract]
  • Pinto, R., Leotta, L., Shanahan, E., West, N., Leyh, T., Britton, W., Triccas, J. (2013), Host cell-induced components of the sulfate assimilation pathway are major protective antigens of Mycobacterium tuberculosis. Journal of Infectious Diseases. 207(5), 778-785. [Abstract]
  • Tran, A., Wen, D., West, N., Baker, E., Britton, W., Payne, R. (2013), Inhibition studies on mycobacterium tuberculosis N-acetylglucosamine-1-phosphate uridyltransferase (GlmU). Organic & Biomolecular Chemistry. 11(46), 8113-8126. [Abstract]
  • Fox, G., Barry, S., Britton, W., Marks, G. (2013), Contact investigation for tuberculosis: a systematic review and meta-analysis. The European Respiratory Journal. 41(1), 140-156. [Abstract]
  • Tyne, A., Chan, J., Shanahan, E., Atmosukarto, I., Chan, H., Britton, W., West, N. (2013), TLR2-targeted secreted proteins from Mycobacterium tuberculosis are protective as powdered pulmonary vaccines. Vaccine. 31(40), 4322-4329. [Abstract]
  • Florido, M., Grima, M., Gillis, C., Xia, Y., Turner, S., Triccas, J., Stambas, J., Britton, W. (2013), Influenza A Virus Infection Impairs Mycobacteria-Specific T Cell Responses and Mycobacterial Clearance in the Lung during Pulmonary Coinfection. Journal of Immunology. 191(1), 302-311. [Abstract]
  • Ritz, N., Casalaz, D., Hanekom, W., Britton, W., Dutta, B., Donath, S., Connell, T., Tebruegge, M., Robins-Browne, R., Curtis, N. (2013), Reply: Bacille Calmette-Guérin vaccine: innate immunity and nonspecific effects. American Journal of Respiratory and Critical Care Medicine. 187(7), 779-780. [Abstract]
  • Giltrap, A., Cergol, K., Pang, A., Britton, W., Payne, R. (2013), Total synthesis of fellutamide B and deoxy-fellutamides B, C, and d. Marine Drugs. 11(7), 2382-2397. [Abstract]
  • Chan, J., Tyne, A., Chan, K., Young, P., Britton, W., Duke, C., Traini, D. (2013), A novel inhaled antibiotic powder to shorten treatment time for latent tuberculosis. RDD Europe 2013.
  • Burke, C., Liu, M., Britton, W., Triccas, J., Thomas, T., Smith, A., Allen, S., Salomon, R., Harry, E. (2013), Harnessing single cell sorting to identify cell division genes and regulators in bacteria. PloS One. 8(4), e60964. [Abstract]
  • Fox, G., Nhung, N., Sy, D., Britton, W., Marks, G. (2013), Household contact investigation for tuberculosis in Vietnam: study protocol for a cluster randomized controlled trial. Trials. 14, 342. [Abstract]


  • Gracey, D., Garsia, R., Britton, W., McKenzie, P. (2012), Rapid recovery of renal function after pulse steroid therapy in a human immunodeficiency virus-infected patient with glomerulonephritis. Internal Medicine Journal. 42(12), 1363-1365. [Abstract]
  • Manos-Turvey, A., Cergol, K., Salam, N., Bulloch, E., Chi, G., Pang, A., Britton, W., West, N., Baker, E., Lott, J., Payne, R. (2012), Synthesis and evaluation of M. tuberculosis salicylate synthase (MbtI) inhibitors designed to probe plasticity in the active site. Organic & Biomolecular Chemistry. 10(46), 9223-9236. [Abstract]
  • Tran, A., West, N., Britton, W., Payne, R. (2012), Elucidation of Mycobacterium tuberculosis type II dehydroquinase inhibitors using a fragment elaboration strategy. ChemMedChem. 7(6), 1031-1043. [Abstract]
  • Nambiar, J., Pinto, R., Aguilo, J., Takatsu, K., Martin, C., Britton, W., Triccas, J. (2012), Protective immunity afforded by attenuated, PhoP-deficient Mycobacterium tuberculosis is associated with sustained generation of CD4(+) T-cell memory. European Journal of Immunology. 42(2), 385-392. [Abstract]
  • Ritz, N., Dutta, B., Donath, S., Casalaz, D., Connell, T., Tebruegge, M., Robins-Browne, R., Hanekom, W., Britton, W., Curtis, N. (2012), The influence of bacille Calmette-Guerin vaccine strain on the immune response against tuberculosis: a randomized trial. American Journal of Respiratory and Critical Care Medicine. 185(2), 213-222. [Abstract]
  • Fox, G., Nhung, N., Sy, D., Lien, L., Cuong, N., Britton, W., Marks, G. (2012), Contact investigation in households of patients with tuberculosis in hanoi, Vietnam: a prospective cohort study. PLoS One. 7(11), e49880. [Abstract]
  • Ritz, N., Strach, M., Yau, C., Dutta, B., Tebruegge, M., Connell, T., Hanekom, W., Britton, W., Robins-Browne, R., Curtis, N. (2012), A comparative analysis of polyfunctional T cells and secreted cytokines induced by Bacille Calmette-Guérin immunisation in children and adults. PLoS One. 7(7), e37535. [Abstract]
  • Kao, F., Mahmuda, S., Pinto, R., Triccas, J., West, N., Britton, W. (2012), The Secreted Lipoprotein, MPT83, of Mycobacterium tuberculosis Is Recognized during Human Tuberculosis and Stimulates Protective Immunity in Mice. PLoS One. 7(5), e34991. [Abstract]
  • Blumenthal, A., Nagalingam, G., Huch, J., Walker, L., Guillemin, G., Smythe, G., Ehrt, S., Britton, W., Saunders, B. (2012), M. tuberculosis Induces Potent Activation of IDO-1, but This Is Not Essential for the Immunological Control of Infection. PLoS One. 7(5), e37314. [Abstract]


  • West, N., Thomson, S., Triccas, J., Medveczky, C., Ramshaw, I., Britton, W. (2011), Delivery of a multivalent scrambled antigen vaccine induces broad spectrum immunity and protection against tuberculosis. Vaccine. 29(44), 7759-7765. [Abstract]
  • Fox, G., Britton, W. (2011), Learning from the genetics of enteric tuberculosis. Journal of Gastroenterology and Hepatology. 26, 1086-1088. [Abstract]
  • West, N., Cergol, K., Xue, M., Randall, E., Britton, W., Payne, R. (2011), Inhibitors of an essential mycobacterial cell wall lipase (Rv3802c) as tuberculosis drug leads. Chemical Communications. 47(18), 5166-5168. [Abstract]
  • Tran, A., Cergol, K., West, N., Randall, E., Britton, W., Bokhari, S., Ibrahim, M., Lapthorn, A., Payne, R. (2011), Synthesis and evaluation of potent ene-yne inhibitors of type II dehydroquinases as tuberculosis drug leads. ChemMedChem. 6(2), 262-265. [Abstract]


  • Wozniak, T., Saunders, B., Ryan, A., Britton, W. (2010), BCG-specific Th17 cells confer partial protection against Mycobacterium tuberculosis infection in the absence of IFN-{gamma}. Infection and immunity. 78(10), 4187-94. [Abstract]
  • Crellin, P., Vivian, J., Scoble, J., Chow, F., West, N., Brammananth, R., Proellocks, N., Shahine, A., Le Nours, J., Wilce, M., Britton, W., Coppel, R., Rossjohn, J., Beddoe, T. (2010), Tetrahydrolipstatin inhibition, functional analyses, and three-dimensional structure of a lipase essential for mycobacterial viability. The Journal of Biological Chemistry. 285(39), 30050-30060. [Abstract]
  • Musicki, K., Briscoe, H., Britton, W., Saunders, B. (2010), LIGHT contributes to early but not late control of Mycobacterium tuberculosis infection. International immunology. 22(5), 353-8. [Abstract]
  • Shanahan, E., Pinto, R., Triccas, J., Britton, W., West, N. (2010), Cutinase-like protein-6 of Mycobacterium tuberculosis is recognised in tuberculosis patients and protects mice against pulmonary infection as a single and fusion protein vaccine. Vaccine. 28(5), 1341-6. [Abstract]
  • Tran, A., Cergol, K., Britton, W., Bokhari, S., Ibrahim, M., Lapthorne, A., Payne, R. (2010), Rapid assembly of potent type II dehydroquinase inhibitors via ‘‘Click’’chemistry. MedChemComm. 1(4), 271-275.
  • Spratt, J., Britton, W., Triccas, J. (2010), In vivo persistence and protective efficacy of the bacille Calmette Guerin vaccine overexpressing the HspX latency antigen. Bioengineered bugs. 1(1), 61-65. [Abstract]
  • Britton, W., Saunders, B. (2010), Pathology and Pathogenesis of Bacterial Infections. In: Immunology of Infectious Diseases. (pp.260-265).United States: ASM Press.
  • Nambiar, J., Ryan, A., Kong, C., Britton, W., Triccas, J. (2010), Modulation of pulmonary dendritic cell function by vaccine-encoded GM-CSF enhances protective immunity against Mycobacterium tuberculosis infection. European Journal of Immunology. 40(1), 153-161. [Abstract]


  • Maddocks, S., Scandurra, G., Nourse, C., Bye, C., Williams, R., Slobedman, B., Cunningham, A., Britton, W. (2009), Gene expression in HIV-1/Mycobacterium tuberculosis co-infected macrophages is dominated by M. tuberculosis. Tuberculosis (Edinburgh, Scotland). 89(4), 285-93. [Abstract]
  • Ryan, A., Nambiar, J., Wozniak, T., Roediger, B., Shklovskaya, E., Britton, W., Fazekas de St Groth, B., Triccas, J. (2009), Antigen load governs the differential priming of CD8 T cells in response to the bacille Calmette Guerin vaccine or Mycobacterium tuberculosis infection. Journal of Immunology. 182(11), 7172-7177. [Abstract]
  • West, N., Chow, F., Randall, E., Wu, J., Chen, J., Ribeiro, J., Britton, W. (2009), Cutinase-like proteins of Mycobacterium tuberculosis: characterization of their variable enzymatic functions and active site identification. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 23(0), 1694-704. [Abstract]
  • Hagge, D., Saunders, B., Ebenezer, G., Ray, N., Marks, V., Britton, W., Krahenbuhl, J., Adams, L. (2009), Lymphotoxin-alpha and TNF have essential but independent roles in the evolution of the granulomatous response in experimental leprosy. The American Journal of Pathology. 174(4), 1379-1389. [Abstract]


  • Ritz, N., Hanekom, W., Robins-Browne, R., Britton, W., Curtis, N. (2008), Influence of BCG vaccine strain on the immune response and protection against tuberculosis. FEMS microbiology reviews. 32(5), 821-841. [Abstract]
  • West, N., Wozniak, T., Valenzuela, J., Feng, C., Sher, A., Ribeiro, J., Britton, W. (2008), Immunological diversity within a family of cutinase-like proteins of Mycobacterium tuberculosis. Vaccine. 26(31), 3853-9. [Abstract]
  • Scandurra, G., Britton, W., Triccas, J. (2008), Inactivation of the Mycobacterium tuberculosis fadB4 gene results in increased virulence in host cell and mice. Microbes and infection / Institut Pasteur. 10(0), 38-44. [Abstract]
  • O'Garra, A., Britton, W. (2008), Cytokines in Tuberculosis. In: Handbook of Tuberculosis: Immunology and Cell Biology. (pp.185-225).Germany: Wiley - VCH Verlag GmbH & Co. KGaA.
  • Britton, W., Triccas, J. (2008), The constituents of the cell envelope and their impact on the host immune system. In: The Mycobacterial Cell Envelope. (pp.249-270).United States: ASM Press.
  • Kaufmann, S., Britton, W. (2008), Handbook of Tuberculosis: Immunology and Cell Biology. Germany: Wiley - VCH Verlag GmbH & Co. KGaA.
  • Weir, R., Fine, P., Floyd, S., Stenson, S., Stanley, C., Branson, K., Britton, W., Huygen, K., Singh, M., Black, G., Dockrell, H. (2008), Comparison of IFN-gamma responses to mycobacterial antigens as markers of response to BCG vaccination. Tuberculosis (Edinburgh, Scotland). 88(1), 31-38. [Abstract]