Publications list for Professor Warwick Britton

2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006

2012

   
  • Nambiar, J., Pinto, R., Aguilo, J., Takatsu, K., Martin, C., Britton, W., Triccas, J. (2012), Protective immunity afforded by attenuated, PhoP-deficient Mycobacterium tuberculosis is associated with sustained generation of CD4(+) T-cell memory. European journal of immunology. 42(2), 385-92. [Abstract]

2011

   
  • West, N., Thomson, S., Triccas, J., Medveczky, C., Ramshaw, I., Britton, W. (2011), Delivery of a multivalent scrambled antigen vaccine induces broad spectrum immunity and protection against tuberculosis. Vaccine. 29(44), 7759-65. [Abstract]
  • Fox, G., Britton, W. (2011), Learning from the genetics of enteric tuberculosis. Journal of Gastroenterology and Hepatology. 26, 1086-1088. [Abstract]
  • West, N., Cergol, K., Xue, M., Randall, E., Britton, W., Payne, R. (2011), Inhibitors of an essential mycobacterial cell wall lipase (Rv3802c) as tuberculosis drug leads. Chemical Communications. 47(18), 5166-5168. [Abstract]

2010

   
  • Tran, A., Cergol, K., West, N., Randall, E., Britton, W., Bokhari, S., Ibrahim, M., Lapthorn, A., Payne, R. (2010), Synthesis and Evaluation of Potent Ene-yne Inhibitors of Type???II Dehydroquinases as Tuberculosis Drug Leads. ChemMedChem. (2). [Abstract]
  • Wozniak, T., Saunders, B., Ryan, A., Britton, W. (2010), BCG-specific Th17 cells confer partial protection against Mycobacterium tuberculosis infection in the absence of IFN-{gamma}. Infection and immunity. 78(10), 4187-94. [Abstract]
  • Crellin, P., Vivian, J., Scoble, J., Chow, F., West, N., Brammananth, R., Proellocks, N., Shahine, A., Le Nours, J., Wilce, M., Britton, W., Coppel, R., Rossjohn, J., Beddoe, T. (2010), Tetrahydrolipstatin inhibition, functional analyses, and three-dimensional structure of a lipase essential for mycobacterial viability. The Journal of Biological Chemistry. 285(39), 30050-30060. [Abstract]
  • Musicki, K., Briscoe, H., Britton, W., Saunders, B. (2010), LIGHT contributes to early but not late control of Mycobacterium tuberculosis infection. International immunology. 22(5), 353-8. [Abstract]
  • Shanahan, E., Pinto, R., Triccas, J., Britton, W., West, N. (2010), Cutinase-like protein-6 of Mycobacterium tuberculosis is recognised in tuberculosis patients and protects mice against pulmonary infection as a single and fusion protein vaccine. Vaccine. 28(5), 1341-6. [Abstract]
  • Spratt, J., Britton, W., Triccas, J. (2010), In vivo persistence and protective efficacy of the bacille Calmette Guerin vaccine overexpressing the HspX latency antigen. Bioengineered bugs. 1(1), 61-65. [Abstract]
  • Tran, A., Cergol, K., Britton, W., Bokhari, S., Ibrahim, M., Lapthorne, A., Payne, R. (2010), Rapid assembly of potent type II dehydroquinase inhibitors via ‘‘Click’’chemistry. MedChemComm. 1(4), 271-275.
  • Nambiar, J., Ryan, A., Kong, C., Britton, W., Triccas, J. (2010), Modulation of pulmonary dendritic cell function by vaccine-encoded GM-CSF enhances protective immunity against Mycobacterium tuberculosis infection. European Journal of Immunology. 40(1), 153-161. [Abstract]

2009

   
  • Maddocks, S., Scandurra, G., Nourse, C., Bye, C., Williams, R., Slobedman, B., Cunningham, A., Britton, W. (2009), Gene expression in HIV-1/Mycobacterium tuberculosis co-infected macrophages is dominated by M. tuberculosis. Tuberculosis (Edinburgh, Scotland). 89(4), 285-93. [Abstract]
  • Ryan, A., Nambiar, J., Wozniak, T., Roediger, B., Shklovskaya, E., Britton, W., Fazekas de St Groth, B., Triccas, J. (2009), Antigen load governs the differential priming of CD8 T cells in response to the bacille Calmette Guerin vaccine or Mycobacterium tuberculosis infection. Journal of Immunology. 182(11), 7172-7177. [Abstract]
  • West, N., Chow, F., Randall, E., Wu, J., Chen, J., Ribeiro, J., Britton, W. (2009), Cutinase-like proteins of Mycobacterium tuberculosis: characterization of their variable enzymatic functions and active site identification. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 23(0), 1694-704. [Abstract]
  • Hagge, D., Saunders, B., Ebenezer, G., Ray, N., Marks, V., Britton, W., Krahenbuhl, J., Adams, L. (2009), Lymphotoxin-alpha and TNF have essential but independent roles in the evolution of the granulomatous response in experimental leprosy. The American Journal of Pathology. 174(4), 1379-1389. [Abstract]

2008

   
  • Ritz, N., Hanekom, W., Robins-Browne, R., Britton, W., Curtis, N. (2008), Influence of BCG vaccine strain on the immune response and protection against tuberculosis. FEMS microbiology reviews. 32(5), 821-841. [Abstract]
  • West, N., Wozniak, T., Valenzuela, J., Feng, C., Sher, A., Ribeiro, J., Britton, W. (2008), Immunological diversity within a family of cutinase-like proteins of Mycobacterium tuberculosis. Vaccine. 26(31), 3853-9. [Abstract]
  • O'Garra, A., Britton, W. (2008), Cytokines in Tuberculosis. In: Handbook of Tuberculosis: Immunology and Cell Biology. (pp.185-225).Germany: Wiley - VCH Verlag GmbH & Co. KGaA.
  • Britton, W., Triccas, J. (2008), The constituents of the cell envelope and their impact on the host immune system. In: The Mycobacterial Cell Envelope. (pp.249-270).United States: ASM Press.
  • Weir, R., Fine, P., Floyd, S., Stenson, S., Stanley, C., Branson, K., Britton, W., Huygen, K., Singh, M., Black, G., Dockrell, H. (2008), Comparison of IFN-gamma responses to mycobacterial antigens as markers of response to BCG vaccination. Tuberculosis (Edinburgh, Scotland). 88(1), 31-38. [Abstract]
  • Kaufmann, S., Britton, W. (2008), Handbook of Tuberculosis: Immunology and Cell Biology. Germany: Wiley - VCH Verlag GmbH & Co. KGaA.
  • Scandurra, G., Britton, W., Triccas, J. (2008), Inactivation of the Mycobacterium tuberculosis fadB4 gene results in increased virulence in host cell and mice. Microbes and infection / Institut Pasteur. 10(0), 38-44. [Abstract]

2007

   
  • Ryan, A., Wozniak, T., Shklovskaya, E., O'Donnell, M., Fazekas de St Groth, B., Britton, W., Triccas, J. (2007), Improved protection against disseminated tuberculosis by Mycobacterium bovis bacillus Calmette-Guerin secreting murine GM-CSF is associated with expansion and activation of APCs. Journal of immunology. 179(12), 8418-8424. [Abstract]
  • Triccas, J., Shklovskaya, E., Spratt, J., Ryan, A., Palindera, U., de St Groth, B., Britton, W. (2007), Effects of DNA- and BCG-based delivery of Flt3 ligand on protective immunity to Mycobacterium tuberculosis. Infection and immunity. 75(11), 5368-75. [Abstract]
  • Almqvist, C., Li, Q., Britton, W., Kemp, A., Xuan, W., Tovey, E., Marks, G. (2007), Early predictors for developing allergic disease and asthma: examining separate steps in the 'allergic march'. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. 37(9), 1296-1302. [Abstract]
  • Weber-Chrysochoou, C., Crisafulli, D., Almqvist, C., Li, Q., Kemp, A., Britton, W., Marks, G. (2007), IL-5 T-cell responses to house dust mite are associated with the development of allergen-specific IgE responses and asthma in the first 5 years of life. The Journal of allergy and clinical immunology. 120(2), 286-92. [Abstract]
  • Fernando, S., Saunders, B., Sluyter, R., Skarratt, K., Goldberg, H., Marks, G., Wiley, J., Britton, W. (2007), A Polymorphism in the P2X7 Gene Increases Susceptibility to Extrapulmonary Tuberculosis. American journal of respiratory and critical care medicine. 175, 360-6. [Abstract]
  • Ryan, A., Spratt, J., Britton, W., Triccas, J. (2007), Secretion of functional Monocyte Chemotactic Protein-3 by recombinant Mycobacterium bovis BCG attenuates vaccine virulence and maintains protective efficacy against M. tuberculosis infection. Infection and immunity. 75(1), 523-6. [Abstract]
  • Scandurra, G., Williams, R., Triccas, J., Pinto, R., Gicquel, B., Slobedman, B., Cunningham, A., Britton, W. (2007), Effect of phthiocerol dimycocerosate deficiency on the transcriptional response of human macrophages to Mycobacterium tuberculosis. Microbes and infection / Institut Pasteur. 9(0), 87-95. [Abstract]
  • Britton, W., Fernando, S., Saunders, B., Sluyter, R., Wiley, J. (2007), The genetic control of susceptibility to Mycobacterium tuberculosis. In: Decoding the Genomic Control of Immune Reactions. (pp.79-89).United Kingdom: John Wiley & Sons. [Abstract]
  • Saunders, B., Britton, W. (2007), Life and death in the granuloma: immunopathology of tuberculosis. Immunology and cell biology. 85, 103-11. [Abstract]

2006

   
  • Wozniak, T., Ryan, A., Britton, W. (2006), Interleukin-23 Restores Immunity to Mycobacterium tuberculosis Infection in IL-12p40-Deficient Mice and Is Not Required for the Development of IL-17-Secreting T Cell Responses. Journal of immunology (Baltimore, Md. : 1950). 177(12), 8684-92. [Abstract]
  • Musicki, K., Briscoe, H., Tran, S., Britton, W., Saunders, B. (2006), Differential requirements for soluble and transmembrane tumor necrosis factor in the immunological control of primary and secondary Listeria monocytogenes infection. Infection and immunity. 74(6), 3180-9. [Abstract]
  • Fernando, S., Britton, W. (2006), Genetic susceptibility to mycobacterial disease in humans. Immunology and cell biology. 84(2), 125-37. [Abstract]
  • Shemon, A., Sluyter, R., Fernando, S., Clarke, A., Dao-Ung, L., Skarratt, K., Saunders, B., Tan, K., Gu, B., Fuller, S., Britton, W., Petrou, S., Wiley, J. (2006), A Thr357 to Ser polymorphism in homozygous and compound heterozygous subjects causes absent or reduced P2X7 function and impairs ATP-induced mycobacterial killing by macrophages. The Journal of biological chemistry. 281(4), 2079-86. [Abstract]
  • Wozniak, T., Ryan, A., Triccas, J., Britton, W. (2006), Plasmid interleukin-23 (IL-23), but not plasmid IL-27, enhances the protective efficacy of a DNA vaccine against Mycobacterium tuberculosis infection. Infection and immunity. 74(1), 557-65. [Abstract]
  • Scandurra, G., Ryan, A., Pinto, R., Britton, W., Triccas, J. (2006), Contribution of L-Alanine Dehydrogenase to In Vivo Persistence and Protective Efficacy of the BCG Vaccine. Microbiology and immunology. 50(10), 805-10. [Abstract]