2011

• Stokes, L., Scurrah, K., Ellis, J., Cromer, B., Skarratt, K., Gu, B., Harrap, S., Wiley, J. (2011), A Loss-of-Function Polymorphism in the Human P2X4 Receptor Is Associated With Increased Pulse Pressure. Hypertension. 58(6), 1086-92. [Abstract]
• Wiley, J., Sluyter, R., Gu, B., Stokes, L., Fuller, S. (2011), The human P2X7 receptor and its role in innate immunity. Tissue Antigens. 78(5), 321-332. [Abstract]
• Gu, B., Saunders, B., Petrou, S., Wiley, J. (2011), P2X7 Is a Scavenger Receptor for Apoptotic Cells in the Absence of Its Ligand, Extracellular ATP. Journal of immunology (Baltimore, Md. : 1950). 187(5), 2365-75. [Abstract]
• Miller, C., Zakrzewski, A., Ikin, R., Boulter, N., Katrib, M., Lees, M., Fuller, S., Wiley, J., Smith, N. (2011), Dysregulation of the inflammatory response to the parasite, Toxoplasma gondii, in P2X(7) receptor-deficient mice. International journal for parasitology. 41(3-4), 301-8. [Abstract]

2010

• Gadeock, S., Tran, J., Georgiou, J., Jalilian, I., Taylor, R., Wiley, J., Sluyter, R. (2010), TGF-beta1 prevents up-regulation of the P2X7 receptor by IFN-gamma and LPS in leukemic THP-1 monocytes. Biochimica et biophysica acta. 1798(11), 2058-66. [Abstract]
• Tran, J., Pupovac, A., Taylor, R., Wiley, J., Byrne, S., Sluyter, R. (2010), Murine epidermal Langerhans cells and keratinocytes express functional P2X receptors. Experimental dermatology. 19(8), e151-7. [Abstract]
• Stokes, L., Fuller, S., Sluyter, R., Skarratt, K., Gu, B., Wiley, J. (2010), Two haplotypes of the P2X7 receptor containing the Ala-348 to Thr polymorphism exhibit a gain-of-function effect and enhanced interleukin-1{beta} secretion. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 24(8), 2916-27. [Abstract]
• Jamieson, S., Peixoto-Rangel, A., Hargrave, A., Roubaix, L., Mui, E., Boulter, N., Miller, E., Fuller, S., Wiley, J., Castellucci, L., Boyer, K., Peixe, R., Kirisits, M., Elias, L., Coyne, J., Correa-Oliveira, R., Sautter, M., Smith, N., Lees, M., Swisher, C., Heydemann, P., Noble, A., Patel, D., Bardo, D., Burrowes, D., McLone, D., Roizen, N., Withers, S., Bahia-Oliveira, L., McLeod, R., Blackwell, J. (2010), Evidence for associations between the purinergic receptor P2X(7) (P2RX7) and toxoplasmosis. Genes and immunity. 11(5), 374-383. [Abstract]
• Lees, M., Fuller, S., McLeod, R., Boulter, N., Miller, C., Zakrzewski, A., Mui, E., Witola, W., Coyne, J., Hargrave, A., Jamieson, S., Blackwell, J., Wiley, J., Smith, N. (2010), P2X7 Receptor-Mediated Killing of an Intracellular Parasite, Toxoplasma gondii, by Human and Murine Macrophages. Journal of immunology (Baltimore, Md. : 1950). 184(12), 7040-6. [Abstract]
• Gu, B., Saunders, B., Jursik, C., Wiley, J. (2010), The P2X7-nonmuscle myosin membrane complex regulates phagocytosis of nonopsonized particles and bacteria by a pathway attenuated by extracellular ATP. Blood. 115(8), 1621-1631. [Abstract]
• Field, J., Browning, S., Johnson, L., Danoy, P., Varney, M., Tait, B., Gandhi, K., Charlesworth, J., Heard, R., Stewart, G., Kilpatrick, T., Foote, S., Bahlo, M., Butzkueven, H., Wiley, J., Booth, D., Taylor, B., Brown, M., Rubio, J., Stankovich, J. (2010), A polymorphism in the HLA-DPB1 gene is associated with susceptibility to multiple sclerosis. PloS One. 5(10), e13454. [Abstract]

2009

• Stevenson, R., Taylor, R., Wiley, J., Sluyter, R. (2009), The P2X(7) receptor mediates the uptake of organic cations in canine erythrocytes and mononuclear leukocytes: comparison to equivalent human cell types. Purinergic signalling. 5(3), 385-94. [Abstract]
• Gu, B., Rathsam, C., Stokes, L., McGeachie, A., Wiley, J. (2009), Extracellular ATP dissociates nonmuscle myosin from P2X(7) complex: this dissociation regulates P2X(7) pore formation. American journal of physiology. Cell physiology. 297(2), C430-9. [Abstract]
• Fuller, S., Stokes, L., Skarratt, K., Gu, B., Wiley, J. (2009), Genetics of the P2X7 receptor and human disease. Purinergic signalling. 5(2), 257-262. [Abstract]
• Bahlo, M., Booth, D., Broadley, S., Brown, M., Foote, S., Griffiths, L., Kilpatrick, T., Lechner-Scott, J., Moscato, P., Perreau, V., Rubio, J., Scott, R., Stankovich, J., Stewart, G., Taylor, B., Wiley, J., Clarke, G., Cox, M., Csurhes, P., Danoy, P., Drysdale, K., Field, J., Greer, J., Hadler, J., McMorran, B., Jensen, C., Johnson, L., McCallum, R., Merriman, M., Merriman, T., Pryce, K., Tajouri, L., Wilkins, E., Browning, B., Browning, S., Perera, D., Butzkueven, H., Carroll, W., Chapman, C., Kermode, A., Marriott, M., Mason, D., Heard, R., Pender, M., Slee, M., Tubridy, N., Willoughby, E. (2009), Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20. Nature Genetics. 41(7), 824-830. [Abstract]

2008

• Forchap, S., Anandacoomarasamy, A., Wicks, J., Di Virgilio, F., Baricordi, O., Rubbini, M., Trotta, F., Wiley, J., Manolios, N. (2008), P2X gene polymorphisms do not appear to be a susceptibility gene locus in sporadic cases of systemic lupus erythematosus. Tissue Antigens. 72(5), 487-490. [Abstract]
• Crowther-Swanepoel, D., Wild, R., Sellick, G., Dyer, M., Mauro, F., Cuthbert, R., Jonsson, V., Matutes, E., Dearden, C., Wiley, J., Fuller, S., Catovsky, D., Houlston, R. (2008), Insight into the pathogenesis of chronic lymphocytic leukemia (CLL) through analysis of IgVH gene usage and mutation status in familial CLL. Blood. 111(12), 5691-5693. [Abstract]
• Fuller, S., Papaemmanuil, E., McKinnon, L., Webb, E., Sellick, G., Dao-Ung, L., Skarratt, K., Crowther, D., Houlston, R., Wiley, J. (2008), Analysis of a large multi-generational family provides insight into the genetics of chronic lymphocytic leukemia. British journal of haematology. 142(0), 238-45. [Abstract]
• Shemon, A., Sluyter, R., Stokes, L., Manley, P., Wiley, J. (2008), Inhibition of the human P2X(7) receptor by a novel protein tyrosine kinase antagonist. Biochemical and biophysical research communications. 365(0), 515-20. [Abstract]

2007

• Sluyter, R., Shemon, A., Hughes, W., Stevenson, R., Georgiou, J., Eslick, G., Taylor, R., Wiley, J. (2007), Canine erythrocytes express the P2X7 receptor: greatly increased function compared to human erythrocytes. American journal of physiology. Regulatory, integrative and comparative physiology. 293(5), R2090-8. [Abstract]
• Jursik, C., Sluyter, R., Georgiou, J., Fuller, S., Wiley, J., Gu, B. (2007), A quantitative method for routine measurement of cell surface P2X(7) receptor function in leucocyte subsets by two-colour time-resolved flow cytometry. Journal of immunological methods. 325, 67-77. [Abstract]
• Sluyter, R., Shemon, A., Wiley, J. (2007), P2X(7) receptor activation causes phosphatidylserine exposure in human erythrocytes. Biochemical and biophysical research communications. 355(1), 169-173. [Abstract]
• Fernando, S., Saunders, B., Sluyter, R., Skarratt, K., Goldberg, H., Marks, G., Wiley, J., Britton, W. (2007), A Polymorphism in the P2X7 Gene Increases Susceptibility to Extrapulmonary Tuberculosis. American journal of respiratory and critical care medicine. 175, 360-6. [Abstract]
• Britton, W., Fernando, S., Saunders, B., Sluyter, R., Wiley, J. (2007), The genetic control of susceptibility to Mycobacterium tuberculosis. In: Decoding the Genomic Control of Immune Reactions. (pp.79-89).United Kingdom: John Wiley & Sons. [Abstract]
• Shemon, A., Sluyter, R., Wiley, J. (2007), Rottlerin inhibits P2X(7) receptor-stimulated phospholipase D activity in chronic lymphocytic leukaemia B-lymphocytes. Immunology and cell biology. 85, 68-72. [Abstract]

2006

• Belov, L., Mulligan, S., Barber, N., Woolfson, A., Scott, M., Stoner, K., Chrisp, J., Sewell, W., Bradstock, K., Bendall, L., Pascovici, D., Thomas, M., Erber, W., Huang, P., Sartor, M., Young, G., Wiley, J., Juneja, S., Wierda, W., Green, A., Keating, M., Christopherson, R. (2006), Analysis of human leukaemias and lymphomas using extensive immunophenotypes from an antibody microarray. British journal of haematology. 135(2), 184-97. [Abstract]
• Gu, B., Wiley, J. (2006), Rapid ATP-induced release of matrix metalloproteinase 9 is mediated by the P2X(7) receptor. Blood. 107(12), 4946-4953. [Abstract]
• Thorselius, M., Krober, A., Murray, F., Thunberg, U., Tobin, G., Buhler, A., Kienle, D., Albesiano, E., Maffei, R., Dao-Ung, L., Wiley, J., Vilpo, J., Laurell, A., Merup, M., Roos, G., Karlsson, K., Chiorazzi, N., Marasca, R., Dohner, H., Stilgenbauer, S., Rosenquist, R. (2006), Strikingly homologous immunoglobulin gene rearrangements and poor outcome inV(H)3-21-using chronic lymphocytic leukemia patients independent of geographic origin and mutational status. Blood. 107(7), 2889-2894. [Abstract]
• Shemon, A., Sluyter, R., Fernando, S., Clarke, A., Dao-Ung, L., Skarratt, K., Saunders, B., Tan, K., Gu, B., Fuller, S., Britton, W., Petrou, S., Wiley, J. (2006), A Thr357 to Ser polymorphism in homozygous and compound heterozygous subjects causes absent or reduced P2X7 function and impairs ATP-induced mycobacterial killing by macrophages. The Journal of biological chemistry. 281(4), 2079-86. [Abstract]