Refereed publications

2018 |2017 |2016 |2015 | 2014 | 2013 | 2012 | 2011 | 2010 | 2009 | 2008 | 2007 | 2006 | 2005 | 2004 | 2003 | 2002 | 2001

2000 | 1999 | 1998 | 1997 | 1996 | 1995 | 1994 | 1993 | 1992 | 1991 | 1990


Hinton T and Johnston GAR "Antagonists of ionotropic receptors for the inhibitory neurotransmitter GABA: therapeutic indications". In GABA And Glutamate - New Developments In Neurotransmission Research, 2018, Chapter 6, DO! 10.5772/intechopen.72678, edited by Janko Samardiz, InTech, Croatia, pages 91-105) [PDF]

Skilbeck KJ. Johnston GAR and Hinton T "Long-lasting effects of early-life intervention in mice on adulthood behaviour, GABAa receptor subunit expression and synaptic clustering" Pharmacological Research, 2018, 128, 179-189) [PDF]


Hinton T, Hanrahan JR and Johnston GAR "Flavonoid actions on receptors for the inhibitory neurotransmitter GABA" In Flavonoids - From Biosynthesis to Human Health", 2017, Chapter 15, edited by Justino GC, InTech, Croatia, pages 335-349) [PDF]

Johnston GAR "Drug analogues and substantial similarity, views of an expert witness" Australian Journal of Forensic Sciences, 2017, 49, 626-636; DOI: 10.1080/00450618.2016.1194476 [PDF]

Johnston GAR "Some personal thoughts on the Australasian Society of Clinical and Experimental Pharmacologists in the 1980s" Pharmacological Research, 2017, 116, 3-6 [PDF]

Johnston GAR "GABA Australis, some reflections on the history of GABA receptor research in Australia" Pharmacological Research, 2017, 116, 32-38 [PDF]

Naffaa MM, Hung S, Chebib M, Johnston GAR and Hanrahan JR, "GABA-ρ receptors: distinctive functions and molecular pharmacology" British Journal of Pharmacology, 2017, 174, 1881-1894 [PDF]

Ng CC, Duke RK, Hinton T and Johnston GAR "Effects of bilobalide, ginkgolide B and picrotoxinin on GABAA receptor modulation by structurally diverse positive modulators" European Journal of Pharmacology, 2017, 806, 83-90 [PDF]


Johnston GAR "Unsaturated analogues of the neurotransmitter GABA: trans-4-aminocrotonic, cis-4-aminocrotonic and 4-aminotetrolic acids" Neurochemical Research, 2016, 41, 476-480 [PDF]

Ng CC, Duke RK, Hinton T and Johnston GAR "GABAa receptor cysteinyl mutants and the ginkgo terpenoid lactones bilobalide and ginkgolides" European Journal of Pharmacology, 2016, 777, 136–146 doi:10.1016/j.ejphar.2016.03.007) [PDF]


Abdelhalim A, Karim N, Chebib M, Aburjai T, Khan I, Johnston GAR and Hanrahan JR "Antidepressant, anxiolytic and antinociceptive activities of constituents from Rosmarinus Officinalis" Journal of Pharmacy & Pharmaceutical Sciences, 2015, 718, 448-459 [PDF]

Hanrahan JR, Chebib M and Johnston GAR "Interactions of flavonoids with ionotropic GABA receptors" Advances in Pharmacology, 2015, 72, 189-200 [PDF]

Johnston GAR "Flavonoid nutraceuticals and ionotropic receptors for the inhibitory neurotransmitter GABA" Neurochemistry International, 2015, 89, 120-125) [PDF]

Rae C, Nasralliah FA, Balcat VJ, Rowlands BD, Johnston GAR and Hanrahan J "Metabolomic approaches to defining the role(s) of GABAρ receptors in the brain" Journal of Neuroimmune Pharmacology, 2015, 10, 445-456) [PDF]


Abdelhalim A, Chebib M, Aburjai T, Johnston GAR and Hanrahan JR , "GABAa receptor modulation by compounds isolated from Salvia triloba L." Advances in Biological Chemistry, Special Issue on Phytochemicals, 2014, 4, 148-159 [PDF]

Blednov YA, Benavidez JM, Black M, Leiter CR, Osterndorff-Kahanek C, Johnson D, Borghese CM, Hanrahan JR, Johnston GAR, Chebib M and Harris RA, "GABA receptors containing ρ1 subunits contribute to in vivo effects of ethanol in mice" PLOS One, 2014, 9(1): e85525. doi:10.1371/journal.pone.0085525 [PDF]

Hall BJ, Karim N, Chebib M, Johnston GAR and Hanrahan JR "Modulation of ionotropic GABA receptors by 6-methoxyflavanone and 6-methoxyflavone" Neurochemical Research, 2014, 39, 1068–1078 [PDF]

Johnston GAR "Muscimol as an ionotropic GABA receptor agonist" Neurochemical Research, 2014, 39, 1942-1947 [PDF]


Gavande N, Kim HL, Doddareddy M, Johnston GAR, Chebib M and Hanrahan JR "Design, synthesis and pharmacological evaluation of fluorescent and biotinylated antagonists of rho1 GABAc receptors" ACS Medicinal Chemistry Letters, 2013, 4, 402-407) [PDF]

Johnston GAR "Advantages of an antagonist: bicuculline and other GABA antagonists" British Journal of Pharmacology, 2013, 169. 328-336 [PDF]

Karim N, Wellendorph P, Absalom N, Johnston GAR, Hanrahan JR and Chebib M "Potency of GABA at human recombinant GABAa receptors expressed in Xenopus oocytes: A mini review" Amino Acids, 2013, 44, 1139-1149 [PDF]

Locock KES, Yamamoto I, Tran P, Hanrahan JR, Chebib M, Johnston GAR and Allan RD "γ-Aminobutyric acid(C) (GABAc) selective antagonists derived from the bioisosteric modification of 4-aminocyclopent-1-enecarboxylic acid: amides and hydroxamates" Journal of Medicinal Chemstry, 2013, 56, 5626-5630 [PDF]


Fernandez SP, Karin N, Mewett KN, Chebib M, Johnston GAR and Hanrahan JR "Flavan-3-ol esters: new agents for exploring modulatory sites on GABA-A receptors" British Journal of Pharmacology, 2012, 165, 965-977 [PDF]

Huang SH, Lewis TG, Lummis SCR, Thompson AJ, Chebib M, Johnston GAR and Duke RK "Mixed antagonistic effects of the ginkgolides at recombinant human rho1 GABAc receptors" Neuropharmacology, 63, 1127-1139 [PDF]

Karim N, Curmi J, Gavande N, Johnston GAR, Hanrahan JR, Tierney ML and Chebib M "2'-Methoxy-6-methylflavone: A novel anxiolytic and sedative with subtype selective activating and modulating actions at GABA-A receptors" British Journal of Pharmacology, 2012, 165, 880-896 [PDF]

Karim N, Wellendorph P, Absalom N, Bang LH, Jensen ML, Hansen MM, Lee HJ, Johnston GAR, Hanrahan JR and Chebib M "Low nanomolar GABA effects at extrasynaptic α4β1/3δ GABAa receptor subtypes indicate a different binding mode for GABA at these receptors" Biochemical Pharmacology, 2012, 84, 549-557 [PDF]

Thompson AJ, McGonigle I, Duke RK, Johnston GAR and Lummis SCR "A single amino acid determines the toxicity of Ginkgo biloba extracts" FASEB Journal, 2012, 26, 1884-1891 [PDF]

Yamamoto I, Absalom N, Carland JE, Doddareddy MR, Gavande N, Johnston GAR, Hanrahan JR, and Chebib M "Differentiating enantioselective actions of GABOB: A possible role for threonine 244 in the binding site of GABAc ρ1 receptors" ACS Chemical Neuroscience, 2012, 3, 665-673) [PDF]

Yamamoto I, Carland JE, Locock KES, Gavande N, Absalom N, Hanrahan JR, Allan, RD, Johnston GAR and Chebib M "Structurally diverse GABA antagonists interact differently with open and closed conformational states of the rho1 receptor" ACS Chemical Neuroscience, 2012, 3, 291-301) [PDF]


Gavande N, Karim N, Johnston GAR, Hanrahan JR and Chebib M "Identification of benzopyran-4-one derivatives (isoflavones) as positive modulators of GABA-A receptors" ChemMedChem, 2011, 6, 1340–1346 [PDF]

Gavande N, Yamamoto I, Salam N, Ai T-H, Burden P, Johnston GAR, Hanrahan JR and Chebib M "Novel cyclic phosphinic acids as GABA-C ρ receptor antagonists: design, synthesis and pharmacology" ACS Med. Chem. Lett. 2011, 2, 11–16 [PDF]

Hanrahan JR. Chebib M and Johnston GAR "Flavonoid modulation of GABA-A receptors" British Journal of Pharmacology 2011, 163, 234-245 [PDF]

Karim N, Gavande N, Wellendorph P, Johnston GAR, Hanrahan JR, and Chebib M "3-Hydroxy-2’-methoxy-6-methylflavone: A potent anxiolytic with a unique selectivity profile at GABA-A receptor subtypes" Biochemical Pharmacology, 2011, 82, 1971-1983 [PDF]

Ng CKL, Kim H-L, Gavande N, Yamamoto I, Kumar RJ, Mewett KN, Johnston GAR, Hanrahan JR and Chebib M "Medicinal chemistry of ρ GABA-C receptors" Future Medicinal Chemistry, 2011, 3, 197-209 [PDF]

Thompson AJ, Jarvis GE, Duke RK, Johnston GAR and Lummis SCR "Ginkgolide and bilobalide block the pore of the 5-HT3 receptor at a location that overlaps with the picrotoxin binding site" Neuropharmacology, 2011, 60, 488-495 [PDF]

Yamamoto I, Deniau GP, Gavande N, Chebib M, Johnston GAR, O’Hagen D "Agonist responses of (R)- and (S)-3-fluoro-γ-aminobutyric acids suggest an enantiomeric fold for GABA binding to GABA-C receptors" ChemComm, 2011, 47, 7956-7958 [PDF]

Yow TT, Pera E, Absalom N, Heblinski M, Johnston GAR, Hanrahan JR and Chebib M (2011) Naringin directly activates inwardly rectifying potassium channels at an overlapping binding site to tertiapin-Q. British Journal of Pharmacology, 2011. 163. 1017-1033 [PDF]


Gavande N, Johnston GAR, Hanrahan JR and Chebib M "Microwave-enhanced synthesis of 2,3,6-trisubstituted pyridazines: application to four-step synthesis of gabazine (SR-95531)" Organic and Biomolecular Chemistry, 2010, 8, 4131–4136 [PDF]

Johnston GAR, Chebib M, Hanrahan JR and Mewett KN "Neurochemicals for the investigation of GABA-C receptors" Neurochemical Research, 2010, 35, 1970-1977 [PDF]

Nasrallah F, Maher, A, Hanrahan JR, Balcar VJ and Rae C "γ-Hydroxybutyrate and the GABAergic footprint. A metabolomic approach to unpicking the actions of GHB" Journal of Neurochemistry, 2010, 115, 58-67.

Skilbeck KJ, Johnston GAR and Hinton T "Stress and GABA-A Receptors" Journal of Neurochemistry, 2010, 112, 1115-1130 [PDF]


Chebib M, Gavande N, Wong KY, Park A, Premoli I, Mewett KN, Allan RD, Duke RK, Johnston GAR and Hanrahan JR "Guanidino acids act as rho1 GABA-C receptor antagonists" Neurochemical Research, 2009, 34, 1704-1711 [PDF]]

Chebib M, Hinton T, Schmid KL,Brinkworth D, Qian H, Matos S, Kim H-L, Abdel-Halim H, Kumar RJ, Johnston GAR and Hanrahan JR (2009) "Novel, potent and selective GABA-C antagonists inhibit myopia development and facilitate learning and memory" Journal of Pharmacology and Experimental Therapeutics, 328, 448-457 [PDF]

Fernandez SP, Nguyen M, Yow TT, Chu C, Johnston GAR, Hanrahan JR and Chebib M "The flavonoid glycosides, myricitrin, gossypin and naringin exert anxiolytic action in mice" Neurochemical Research, 2009, 34, 1867-1878 [PDF]

Hanrahan JR and Johnston GAR (2009) Synthesis of γ-aminobutyric acid analogues. In: Amino Acids, Peptides and Proteins in Organic Chemistry, Volume 1, Origins and synthesis of amino acids, Ed AB Hughes, Wiley VCH, Weinheim, pp. 573-689 [PDF]

Hinton T and Johnston GAR "Anxiolytic and hypnotic drugs acting on ionotropic GABA receptors" Encyclopedia of Neuroscience, edited by MD Binder, N Hirokawa, and U Windhorst, Springer-Verlag, 2009, pp 154-159 [PDF]

Johnston GAR, Chebib M, Duke RK, Fernandez SP, Hanrahan JR, Hinton T and Mewett KN "Herbal products and ionotropic GABA receptors" New Encyclopedia of Neuroscience, edited by LR Squire, Elsevier, 2009, 4, 1095-1101 [PDF]

Locock KES, Johnston GAR and Allan RD "GABA analogues derived from 4-aminocyclopent-1-enecarboxylic acid" Neurochemical Research, 2009, 34, 1698-1703 [PDF]

McIntosh JM, Absalom N, Chebib M, Elgoyhen AB, Vincler M "Alpha9 nicotinic acetylcholine receptors and the treatment of pain" Biochemical Pharmacology, 2009, 78, 693-702

Mewett KN, Fernandez SP, Pasricha AK, Pong A, Devenish SO, Chebib M, Johnston GAR, Hibbs DE and Hanrahan JR "Synthesis and biological evaluation of flavan-3-ol derivatives as positive modulators of GABA-A receptors" Bioorganic & Medicinal Chemistry, 2009, 17, 7156-7173 [PDF]


Abdel-Halim H, Hanrahan JR, Hibbs DE, Johnston GAR and Chebib M "A molecular basis for agonist and antagonist actions at GABA-Creceptors" Chemical Biology and Drug Design, 2008, 71, 306-327 [PDF]

Carland JE, Johnston GAR and Chebib M "Relative impact of residues at the intracellular and extracellular ends of the human GABA-C rho1 receptor M2 domain on picrotoxinin activity" European Journal ofPharmacology, 2008, 580, 27-35 [PDF]

Fernandez SP, Mewett KN, Hanrahan JR, Chebib M, Johnston GAR "Flavan-3-ol derivatives are positive modulators of GABA-A receptors with higher efficacy for the alpha2 subtype and anxiolytic action in mice" Neuropharmacology, 2008, 55, 900-907 [PDF]

Hinton T, Chebib M and Johnston GAR "Enantioselective actions of 4-amino-3-hydroxybutanoic acid and (3-amino-2-hydroxypropyl)methylphosphinic acid at recombinant GABA-C receptors" Bioorganic & Medicinal Chemistry Letters 2008, 18, 402-404 [PDF]

Hinton T and Johnston GAR "The role of GABA-A receptors in schizophrenia" Cell Science Reviews, 2008, 5, 180-194[PDF]

Kumar RJ, Chebib M, Hibbs DE, Kim H-L, Johnston GAR, Salam NK andHanrahan JR "Novel gamma-aminobutyric acid rho1 receptor antagonists; Synthesis, pharmacological activity and structure activity relationships" Journal of Medicinal Chemistry, 2008, 51, 3825-3840) [PDF]

Skilbeck KJ, Hinton T and Johnston GAR "Sex-differences andstress: effects on regional high and low affinity [3H]GABA binding" Neurochemistry International, 2008, 52,1212-1219 [PDF]

Skillbeck KJ, O'Reilly JN, Johnston GAR and Hinton T "Antipsychotic drug administration differentially affects[3H]muscimol and [3H]flunitrazepam GABA-A receptor binding sites" Progress in Neuropsychopharmacology & Biological Psychiatry, 2008, 32, 492-498 [PDF]


Chebib M, Hanrahan JR, Kumar RJ, Mewett KN, Morriss G, Wooller S and Johnston GAR "(3-Aminocyclopentyl)methylphosphinic acids: NovelGABA-C receptor antagonists" Neuropharmacology, 2007, 52, 779-787 [PDF]

Skilbeck KJ, O'Reilly JN, Johnston GAR and Hinton T "The effects of antipsychotic drugs on GABA-A receptor binding depend on period of drug treatment and binding site examined" Schizophrenia Research, 2007, 90, 76-80 [PDF]


Crittenden DL, Park, A, Qiu J, *Silverman RB, Duke RK, Johnston GAR, **Jordan MJT and Chebib M "Enantiomers of cis-constrained and flexible 2-substituted GABA analogues exert opposite effects at recombinant GABA-C receptors" Bioorganic and Medicinal Chemistry, 2006, 14, 447-455 [PDF]

Fernandez SP, *Wasowski C , *Loscalzo LM, Granger RE, JohnstonGAR, *Paladini AC and *Marder M "Central nervous system depressant action of flavonoid glycosides" European Journal ofPharmacology, 2006, 539, 168-176 [PDF]

Greenwood JR, Mewett KN, Allan RD, *Martin BO, *Pickering DS (2006) "3-hydroxypyridazine 1-oxides as carboxylate bioisosteres: a new series of subtype-selective AMPA receptoragonists". Neuropharmacology, 51, 52-59

Hanrahan JR, Mewett KN, Chebib M, Matos S, Eliopoulos CT, Crean C,Kumar RJ, Burden P, and Johnston GAR "Diastereoselective synthesis of(±)-(3-aminocyclopentanyl)alkylphosphinic acids, conformationally restricted analogues of GABA" Organic & Biomolecular Chemistry, 2006, 4, 2642-2649 [PDF]

Huang SH, Duke RK, Chebib M, Sasaki K, Wada K and Johnston GAR (2006) Mixed antagonistic effects of bilobalide at rho1 GABA-C receptors, Neuroscience, 2006, 137, 607-617 [PDF]

Johnston GAR, Hanrahan JR, Chebib M, Duke RK and Mewett KN. Modulation of ionotropic GABA receptors by natural products of plantorigin, Adv. Pharmacol., 2006, 54, 285-316 [PDF]


Crittenden DL, Chebib M and **Jordan MJT "Stabilization of zwitterions in solution: GABA analogues" Journal of PhysicalChemistry A, 2005, 109, 4195-4201

Crittenden DL, Kumar RJ, Hanrahan JR, Chebib M and **Jordan MJT "Stabilization of zwitterions in solution: phosphinic and phosphonic acid GABA analogues" Journal of Physical Chemistry A, 2005, 109, 8398-8409

*Gibbs ME and Johnston GAR "Opposing roles for GABA-A and GABA-C receptors in short-term memory formation in young chicks" Neuroscience, 2005, 131, 567-576 [PDF]

Granger RE, Campbell EL and Johnston GAR "(+) and (-)-Borneol:efficacious positive modulators of GABA action at human recombinantalpha1beta2gamma2L GABA-A receptors" Biochemical Pharmacology,2005, 69, 1101-1111 [PDF]

Hall BJ, Chebib M, Hanrahan JR and Johnston GAR "6-Methylflavanone, a more efficacious positive allosteric modulatorof gamma-aminobutyric acid (GABA) action at human recombinant alpha2beta2gamma2L than at alpha1beta2gamma2L and alpha1beta2 GABA-A receptors expressed in Xenopus oocytes" European Journal of Pharmacology, 2005, 512, 97-104 [PDF]

Henderson JM, Schleimer S, Allbutt H, Dabholkar V, Abela D, JovicJ and Quinlivan M "Behavioural effects of parafascicular thalamic lesions in an animal model of parkinsonism" Behavioural BrainResearch 2005, 162, 222-232

James ML, Fulton RR, Henderson DJ,Eberl S, Meikle SR,ThomsonS, Allan RD, Dolle F, Fulham MJ, and Kassiou M. Synthesis and invivo evaluation of a novel peripheral benzodiazepine receptor PET radioligand, Bioorganic & Medicinal Chemistry 2005, 13, 6188-6194

Johnston GAR , GABA-A receptor channel pharmacology, CurrentPharmaceutical Design, 2005, 11, 1867-1885 [PDF]

Schleimer SB, Johnston GAR and Henderson JM "Novel oral drug administration in an animal model of chronic neuroleptic therapy" Journal of Neuroscience Methods, 2005, 146, 159-164 [PDF]


Allan RD, Greenwood J, **Hambley TW, Hanrahan JR, **Hibbs DE, **Itani S, Tran HW and **Turner P. "Studies on Pyridazine Azide Cyclisation Reactions" Organic & Biomolecular Chemistry,2004, 2, 1782-1788

Campbell EL, Chebib M and Johnston GAR "The dietary flavonoids apigenin and (-)-epigallocatechin gallate enhance the positive modulation by diazepam of the activation by GABA of recombinant GABA-A receptors" Biochemical Pharmacology, 2004, 68,1631-1638 [PDF]

Carland JE, Moorhouse AJ, Barry PH, Johnston GAR and Chebib M "Charged residues at the 2' position of human GABA-C rho1 receptors invert ion selectivity and influence open state probability" Journal of Biological Chemistry, 2004, 279, 54153-54169[PDF]

Carland JE, *Moore AM, Hanrahan JR, Mewett KN, Duke RK, Johnston GAR and Chebib M "Mutations of the 2' proline in the M2 domain of the human GABA-C rho1 subunit alter agonist responses" Neuropharmacology, 2004, 46, 770-781 [PDF]

Chebib M, Hanrahan JR, Mewett KN, Duke RK and Johnston GAR "Ionotropic GABA receptors as therapeutic targets for memory and sleep disorders" Annual Reports in Medicinal Chemistry, 2004, 39, 13-23 [PDF]

Duje RK, Chebib M, **Hibbs DE, Mewett KN and Johnston GAR "Synthesis and resolution of 2-methyl analogues of GABA" Tetrahedron Asymmetry, 2004, 15, 1745-1751 [PDF]

Hall BJ, Chebib M, Hanrahan JR and Johnston GAR "Flumazenil-independent positive modulation of GABA action by 6-methylflavone at human recombinant alpha1, beta2, gamma2L andalpha1, beta2 GABA-A receptors" European J. Pharmacology,2004, 491, 1-8 [PDF]

Henderson DJ, *Eberl S, *Thomson S, *Smith A, Allan RD, *Fulham MJ, *Loiacono R, Kassiou M. (2004) 3-Pyridyl ethers as SPECT radioligands for imaging nicotinic acetylcholine receptors. ApplRadiation and Isotopes. 60(5):669-76.

Huang SH , Duke RK, Chebib M, Sasaki K, Wada K and Johnston GAR,Ginkgolides, diterpene trilactones of Ginkgo biloba, as antagonists at recombinant alpha1, beta2, gamma2L GABA-A receptorsEuropean Journal of Pharmacology, 2004, 494, 131-138[PDF]

Johnston GAR and *Beart PM "Flavonoids: some of the wisdom of sage?" British Journal of Pharmacology, 2004, 142,809-810 [PDF]

**Lee NA, **Wang S, Allan RD and **Kennedy IR (2004) A rapidaflatoxin B1 ELISA: development and validation with reduced matrix effects for peanuts, corn, pistachio, and Soybeans. J Agric FoodChem., 2004 , 52, 2746-55.

Schliemer SB, Hinton T, Dixon G and Johnston GAR "GABA transporters GAT-1 and GAT-3 in the human dorsolateral prefrontalcortex in schizophrenia" Neuropsychobiology, 2004, 50,226-230 [PDF]


Chebib M, Duke RK, Connor M, Mewett KN and Johnston GAR "Convulsant actions of calycanthine" Toxicology and AppliedPharmacology, 2003, 190, 58-64 [PDF]

Hanrahan JR, Chebib M, Davucheron NM, Hall BJ and Johnston GAR(2003) "Semisynthetic preparation of amentoflavone: a negative modulator at GABA-A receptors" Bioorganic & Medicinal Chemistry Letters, 2003, 13, 2281-2284 [PDF]

**Hibbs DE, Hanrahan JR, **Hurtshouse MB, *Knight DW, **OvergaardJ, **Turner P, **Piltz RO and **Waller MP "Experimental and theoretical charge distribution in (Z)-N-methyl-C-phenylnitrone" Organic & Biomolecular Chemistry, 2003, 1,1034-1040

Huang SH, Duke RK, Chebib M, *Sasaki K, *Wada K and Johnston GAR "Bilobalide, a sesquiterpene trilactone from Ginkgo biloba, is an antagonist at recombinant α1β2γ2LGABA-A receptors" European Journal of Pharmacology, 2003, 464, 1-8 [PDF]

Johnston GAR "Dietary chemicals and brain function" Journal & Proceedings of the Royal Society of New South Wales, 2003, 135, 57-71 [PDF]

Johnston GAR, Chebib M, Hanrahan JR and Mewett KN "GABA-C receptors as drug targets" Current Drug Targets - CNS & Neurological Disorders, 2003, 2, 260-268 [PDF]

*Krehan D, *Frølund B, *Krogsgaard-Larsen, P, *Kehler J, Johnston GAR and Chebib M "Phosphinic, phosphonic and seleninic acid bioisosteres of isonipecotic acid as novel and selective GABA-C receptor antagonists" Neurochemistry International, 2003, 42, 561-565 [PDF]

*Krehan D, *Frølund B, *Krogsgaard-Larsen, P, Johnston GARand Chebib M "Aza-THIP and related analogues of THIP as GABA-C antagonists" Bioorganic and Medicinal Chemistry, 2003, 11, 4891-4896) [PDF]

**Waller MP, **Hibbs DE, Overgaard J, Hanrahan JR, **Hambley TW "Flavone" Acta Crystallographia, Section E. Structure ReportsOnline, 2003, E59, o767-768


Duke RK, Chebib M, Duke CC, Johnston GAR and Roufogalis BD "Ginkgo biloba - food for the brain" New Zealand Pharmacy, 2002, 22(5), 27-33 [PDF][[/adrien-albert/images/pdfs/RefsPDFs/350.pdf||]]

Johnston GAR "Medicinal chemistry and molecular pharmacology of GABA-C receptors" Current Topics in Medicinal Chemistry, 2002, 2, 903-913 [PDF]

*Topliss JG, *Clark AM, *Ernst E., *Hufford C, Johnston GAR ,*Rimoldi JM and *Weimann BJ "Natural and synthetic substances related to human health (IUPAC Technical Report)" Pure and Applied Chemistry, 2002, 74, 1957-1985 [PDF]

Vien J, Duke RK, Mewett KN, Johnston GAR, *Shingai R and Chebib M "trans-4-Amino-2-methylbut-2-enoic acid (2-MeTACA) and(±)-trans-2-aminomethylcyclopropanecarboxylic acid ((±)-TAMP) can differentiate rat rho-3 from human rho-1 and rho-2 recombinant GABA-C receptors" British Journal ofPharmacology, 2002, 135, 883-890 [PDF]


Chebib M "Novel agents acting on GABA-C receptors: potential cognitive enhancers" Chemistry in Australia, 2001, 68(9), 19-21

Chebib M, Duke RK, Allan RD and Johnston GAR "The effects of cyclopentane and cyclopentene analogues of GABA at recombinant GABA-C receptors" European Journal of Pharmacology, 430, 185-192 [PDF]

Dodds HM, Hanrahan JR and Rivory LP "The inhibition of acetylcholinesterase by irinotecan and related camptothecins: key structural properties and experimental variables" Anti-cancer Drug Design, 2001, 16, 239-249

Farrar NS, Chambers NJ, Carlsson AR, **Denyer G and Johnston GAR "Effect of a series of novel sulfonylthioureas on glucose tolerance in the obese fa/fa Zucker rat" Clinical and Experimental Pharmacology and Physiology, 2001, 28, 386-391 [PDF]

Hall BJ, Hanrahan JR, Johnston GAR, **Hambley TW and Hibbs DE "6-Methylflavone" Acta Crystallographia, 2001, E57,o592-o593) ( [PDF]

Hanrahan JR, Mewett KN, Chebib M, Burden PM and Johnston GAR, An improved, versatile synthesis of the GABA-C antagonists (1,2,5,6-tetrahydropyridin-4-yl)methylphosphinic acid (TPMPA) and (piperidin-4-yl)methylphosphinic acid (P4MPA) J. Chem. Soc.,Perkin Trans. 1, 2001, 19, 2389-2392 [PDF]

Hanrahan JR, *Knight DW and *Salter R "On the characteristics of reverse-Cope cyclizations of homoallylic sulfoxide nitrone adducts: ahighly stereoselective route to pyrrolidine-N-oxides" Synlee,2001, 10, 1587-1589


Burden PM, Ai TH, Lin HQ, Akinci M, Costandi M, **Hambley TM and Johnston GAR "Chiral derivatives of2-cyclohexylideneperhydro-4,7-methanoindenes, a novel class ofnonsteroidal androgen receptor ligand. Synthesis, X-ray analysis andbiological activity" Journal of Medicinal Chemistry, 2000, 43, 4629-4635 [PDF]

Chebib M and Johnston GAR "GABA-activated ligand gated ionchannels: medicinal chemistry and molecular biology" Journal ofMedicinal Chemistry, 2000, 43, 1427-1447 [PDF]

Chebib M and *Quinn RJ "1-Phenylpyrazolo[3,4-d]pyrimidines: Structure-activityrelationships for C6 substituents at A1 and A2a Adenosine receptors" Bioorganic and Medicinal Chemistry, accepted 1.7.99

Duke RK, Chebib M, **Balcar VJ, Allan RD, Mewett KN and JohnstonGAR "(+)- and (-)-cis-2-Aminomethylcyclopropanecarboxylic acidshow opposite pharmacology at recombinant r1and r2 GABACreceptors" Journal of Neurochemistry, 2000, 75, 2602-2610) [PDF]

Farrar N "New drug balances the diabetic see-saw" AustralasianScience, 2000, 21(9), 30-31

Johnston GAR "The medicinal chemistry-molecular biology interface:recombinant receptors in the search for new drugs" in Technology & Health, Proceedings of the 13th Convocation of the Council ofAcademies of Engineering and Technological Sciences, ISBN2-7430-0386-3, Paris, France, 2000, pp 72-74

Johnston GAR "GABA Chemistry: Analogs of GABA as therapeutic andinvestigational agents" in GABA in the Nervous System: The Viewat Fifty Years, Edited by David L. Martin and Richard W. Olsen,Lippincott Williams & Wilkins Publishers, Philadelphia, PA, USA,65-80

Johnston GAR, Chebib M, Duke RK "Ionotropic GABA receptors: ligandgated ion channels" in Control and Diseases of Sodium Dependent Transport Proteins and Ion Channels, Edited by Y Suketa, E Carafoli,M Lazdunski, K Mikoshiba, Y Okada and EM Wright, Elsevier Science, Amsterdam, The Netherlands, pp. 369-372, 2000

*Li Y, *Wood N, Grimsley P, *Yellowlees D and Donelly PK "In vitroinvasiveness of human breast cancer cells is promoted by low densitylipoprotein receptor-related protein" Invasion Metastasis,2000, 18, 240-251

**Lieb I, Chebib M, **Cooper B, **Dias LS and **Balcar VJ "Quantitative Autoradiography of Na+-dependent[3H]L-aspartate binding to L-glutamatetransporters in rat brain: Structure-activity studies usingL-trans-pyrrolidine-2,4-dicarboxylate (L-t-PDC) and2-(Carboxycyclopropyl)-glycine (CCG)" NeurochemistryInternational, 2000, 36, 319-327


Chebib M and Johnston GAR "The ABC of GABA receptors: A briefreview" Clinical and Experimental Pharmacology and Physiology,1999, 26, 937-940 [PDF]

Chebib M, Johnston GAR, *Mattsson JP, *Rydström K, *NilssonK, *Qiu K, *Stevenson SH and *Silverman RB "Aminomethyl-2,6-difluorophenols as a novel class of increasedlipophilicity GABA-C receptor antagonists" Bioorganic & Medicinal Chemistry Letters, 1999, 9, 3093-3098 [PDF]

Cooper EJ, Johnston GAR and Edwards FA "Effects of a naturallyoccurring neurosteroid on GABA-A IPSCs during development in rathippocampal or cerebellar slices" Journal of Physiology, 1999, 521.2, 437-449 [PDF]

*Cordato DJ, Chebib M, *Mather LE, *Herkes GK and Johnston GAR,Stereoselective interaction of thiopentone enantiomers with theGABAA receptor, British Journal of Pharmacology,1999, 128, 77-82 [PDF]

Johnston GAR, Chebib M, Duke RK, Mewett KN, Mitrovic AD andVandenberg RJ, Medicinal chemistry and molecular pharmacology of GABAreceptors and glutamate transporters: complementarystructure-activity relationships, Drug Development Research,1999, 46, 255-260 [PDF]

Lin HQ, Burden PM, Christie MJ and Johnston GAR "Theanxiogenic-like and anxiolytic-like effects of MDMA on mice in theelevated plus maze: a comparison with amphetamine" Pharmacology,Biochemistry and Behavior, 1999, 62, 403-408 [PDF]

Mitrovic AD, Maddison JE and Johnston GAR "Influence of theoestrous cycle on L-glutamate and L-aspartate transport in rat brainsynaptosomes" Neurochemistry International, 1999, 34,101-108 [PDF]

*Wang S, Allan RD, *Skerritt JH and **Kennedy IR "Development ofa compound-specific ELISA for flufenoxuron and an improvedclass-specific assay for benzoylphenylurea insect growth regulators" Journal of Agricultural & Food Chemistry, 1999, 47, 3416-3424


Burden PM, Allan RD, **Hambley T and Johnston GAR "The Synthesis of 2-Cyclohexylideneoctahydro-4,7-methano-1H-indenes. Non-Steroidal Analogues of Steroidal GABAA Receptor Modulators" Journal of the Chemical Society, Perkin Transactions 1, 1998,3163-3169. [PDF]

Chebib M, Mewett KN and Johnston GAR "GABAC receptorant agonists differentiate between human rho1 and rho2 receptors expressed in Xenopus oocytes" European Journal ofPharmacology, 1998, 357, 227-234. [PDF]

**Cooper B, Chebib M, **Shen J, **King NJC, **Kuchel PW,*Rothstein JD and **Balcar VJ "Structural selectivity and molecular nature of L-glutamate transport in cultured human fibroblasts",Archives of Biochemistry and Biophyscis, 1998, 353,356-364.

Duke RK, Allan RD, Chebib M, Greenwood JR and Johnston GAR "Resolution and conformational analysis of diastereoisomers ofcis- andtrans--2-(aminomethyl)-1-carboxycyclopropanes" Tetrahedron Asymmetry, 1998, 9, 2533-2548. [PDF]

Greenwood JR, Vaccarella G, Capper HR, Allan RD and Johnston GAR(1998) "Heterocycles as bioisosteres for the w-carboxylate moiety of glutamate in AMPA receptor agonists: A review and theoretical study". Internet Journal of Chemistry 1, 38

Lin HG, Burden PM and Johnston GAR "Propylene glycol elicits anxiolytic-like responses to the elevated plus maze in male mice" Journal of Pharmacy and Pharmacology, 1998, 50,1127-1131.

Mitrovic AD, *Amara SG, Johnston GAR and Vandenberg RJ "Identification of functional domains of the human glutamate transporters EAAT1 and EAAT" Journal of Biological Chemistry,1998, 273, 14698-14706. [PDF]

Vandenberg RJ "Molecular pharmacology and physiology of glutamate transporters" Clinical and Experimental Pharmacology and Physiology, 1998, 25, 393-400.

Vandenberg RJ, Mitrovic AD and Johnston GAR "Serine-O-sulfate transport by the human glutamate transporter EAAT2" British Journal of Pharmacology, 1998, 123, 1593-1600. [PDF]

Vandenberg RJ, Mitrovic AD and Johnston GAR "Molecular basis for differential inhibition of glutamate transporter subtypes by zinc ions" Molecular Pharmacology, 1998, 54, 189-19.[PDF]

*Wang S, Allan RD, *Skerritt JH and **Kennedy IR "Development of a class-specific competitive ELISA for the benzoylphenylurea insecticides" Journal of Agricultural and Food Chemistry,1998, 46, 3330-3338.


Akinci MK and Johnston GAR "Sex differences in the effects of gonadectomy and acute swim stress on GABAA receptor binding in mouse forebrain membranes" Neurochemistry International, 1997, 31, 1-10 [PDF]

Allan RD, Dickenson HW, Johnston GAR, Kazlauskas R and Mewett KN "Structural analogues of ZAPA as GABAA agonists" Neurochemistry International, 1997, 30, 583-59 [PDF]

Chebib M and Johnston GAR "Stimulation of [3-H]GABA and[3-H]beta-alanine release from rat brain slices bycis-4-aminocrotonic acid" Journal of Neurochemistry , 1997, 68, 786-794 [PDF]

Chebib M and *Quinn RJ "1-Phenylpyrazolo[3,4-d]pyrimidinesas adenosine antagonists: the effects of substituents at C4 and C6" Bioorganic and Medicinal Chemistry, 5, 311-322

Chebib M, Vandenberg RJ, *Froestl W and Johnston GAR "Unsaturatedphosphinic analogues of GABA as GABAC receptor antagonists" European Journal of Pharmacology, 1997, 329, 223-239 [PDF]

Chebib C, Vandenberg RJ and Johnston GAR "Analogues of amma-aminobutryic acid (GABA) and trans–4-aminocrotonic acid (TACA) substituted in the 2 position as GABAC receptor antagonists" British Journal of Pharmacology, 1997, 122, 1551-156 [PDF]

Greenwood JR, Capper HR, Allan RD and Johnston GAR "Tautomerism of hydroxy-pyridazines: the N-oxides" Journal of Molecular Structure(Theochem), 1997, 419, 97-11

Johnston GAR "Cerebral chemistry" Chemistry in Australia,1997, 64(5), 34-36; reprinted in the Australian Chemistry Resource Book, 1997, 16, 67-72

Johnston GAR "GABAC receptors: molecular biology, pharmacology and physiology". In: The GABA Receptors, *EnnaSJ, *Bowery NG eds, 2nd edition, Humana Press, New Jersey, 1997,297-323

Maddalena DJ and *Snowdon GM "Applications of genetic algorithms to drug design" Expert Opinion in Therapeutic Patents, 1997, 7, 247-254

Vandenberg R, Mitrovic A, Chebib M, **Balcar VJ and Johnston GAR "Contrasting modes of action of methylglutamate derivatives on the excitatory amino acid transporters, EAAT1 and EAAT2" Molecular Pharmacology, 1997, 51, 809-815 [PDF]


Allan RD, Duke RK, **Hambley TW, Johnston GAR, Mewett KN, Quickert N and Tran HW "Synthesis of unsaturated analogues of glutamic acid by amination of trianions from unsaturated dicarboxylic acids with chloramine" Aust. J. Chem., 1996, 49, 785-79)

Cooper EJ, Johnston GAR and Edwards FA "Differential sensitivity during development of GABA-mediated synaptic transmission to a neuroactive steroid in rat hippocampus and cerebellum". In GABA :Receptors, Transporters and Metabolism, edited by C. Tanaka andN.G. Bowery, Birkhäuser, Basel, 1996, pp. 195-200

Dodd P, Kril JJ, *Thomas GJ, Watson WEJ, Johnston GAR and **Harper CG "Receptor binding sites and uptake activities mediating GABA neurotransmission in chronic alcoholics with Wernicke encephalopathy" Brain Research, 1996, 710, 215-228

Greenwood JR, Vaccarella G, Capper HR, Mewett KN, Allan RD and Johnston GAR "Theoretical studies on the free-radical bromination of methyl-pyridazines in the synthesis of novel heterocyclic analogues of neurotransmitters" Journal of Molecular Structure (Theochem),1996, 368, 235-243

Johnston GAR "GABAA receptor pharmacology" Pharmacology & Therapeutics, 1996, 69, 173-198

Johnston GAR "Small molecules as drugs" Chemistry inAustralia, 1996, 64, 212-213

Johnston GAR "GABA-C receptors: relatively simple transmitter-gated ion channels?" Trends in Pharmacological Sciences, 1996, 17, 319-323 [PDF]

Maddison JE, Watson WEJ and Johnston GAR "Synaptosomal and brain slice cerebrocortical 3H-L-glutamate uptake in a rat model of hepatic encephalopathy" Neurochemistry International,1996, 28, 89-93


Allan RD, Apostopoulos C and **Hambley TW "The synthesis and structure of a cyclobutane analogue of glutamic acid with an acetic acid sidechain" Australian Journal of Chemistry, 1995, 48, 919-928

Duke DK, Allan RD, **Duke CC, **Hambley TW, Johnston GAR, Mewett KN and Mitrovic AD "Idiospermuline, a trimeric pyrroldinoindoline alkaloid from the seed of Idiospermum australiense" Journal of Natural Products Lloydia, 1995 58,1200-1208

Johnston GAR "GABA receptor pharmacology". In Pharmacological Sciences: Perspectives for Research and Therapy in the late 1990s,edited by AC Cuello and B Collier, Birkhäuser, Basel, 1995,pp. 11-15

Maddalena DJ and Johnston GAR "Prediction of receptor properties and binding affinity of ligands to benzodiazepine/GABA-A receptors using artificial neural networks" Journal of Medicinal Chemistry, 1995, 38, 715-724)


*Frydenvang K, *Krogsgaard-Larsen P, *Hansen JJ, Mitrovic A, TranH, Drew CA and Johnston GAR "GABAB antagonists:resolution, absolute stereochemistry and pharmacology of (R)- and(S)-phaclofen" Chirality, 1994, 6, 583-589

Johnston GAR "GABAC receptors" Progress in BrainResearch, 1994, 100, 61-65

Johnston GAR "GABA receptors - as complex as ABC?" Clinicaland Experimental Pharmacology and Physiology, 1994, 21,521-526

Maddalena DJ and Johnston GAR "Application of neural networks to quantitative structure-activity relationships of benzodiazepine/GABAA receptor binding compounds" in The Challenge of Neuropharmacology, a Tribute to the Memory of Willy Haefely, edited by H. Möhler & M. Da Prada, EditionesRoche, Basel, 1994, pages 136-139

Mitrovic AD and Johnston GAR "Regional differences in the inhibition of L-glutamate and L-aspartate sodium-dependent high affinity uptake systems in rat CNS synaptosomes byL-trans-pyrrolidine-2,4-dicarboxylate,threo-3-hydroxy-D-aspartate and D-aspartate" Neurochemistry International, 1994, 24, 583-588


Akinci MK and Johnston GAR "Sex differences in acute swim stress induced changes in the binding of MK-801 to the NMDA subclass of glutamate receptors in mouse forebrain" Journal ofNeurochemistry, 1993, 61, 2290-2293)

Burden PM and Allan RD "A facile synthesis of 2-imino-1-pyrrolidinealkanoic acids" 1993, 23, 1195-1199

Dodd PR, Leong PR and Johnston GAR "A Huntington Disease factor which inhibits [3H]kainate binding also blocks synaptosomal amino acid transport in rat brain" Neurochemistry International, 1993, 23, 131-13

Duke RK, Allan RD, Drew CA, Johnston GAR, Mewett KN, *Long MA and*Than C "The preparation of tritiated E- andZ-4-aminobut-2-enoic acids, conformationally restricted analogues of the inhibitory neurotransmitter 4-aminobutanoic acid (GABA)" Journal of Labelled Compounds and Radiopharmaceuticals, 1993, 33, 527-540

Duke RK, Allan RD, Drew CA, Johnston GAR, Mewett KN, *Long MA and *Than C "The synthesis and resolution of tritiated4-amino-3-phenylbutanoic acid ([3H]R- and[3H]S-beta-phenylGABA" Journal of Labelled Compounds and Radiopharmaceuticals, 1993, 33, 767-775


Capper HR, Mewett KN, Allan RD and Johnston GAR "Molecular modelling of N-methyl-D-aspartate (NMDA) receptor agonists and antagonists" Molecular Neuropharmacology, 1992, 2,83-87

Davies LP, Drew CA, *Duffield PM Johnston GAR and *Jamieson DD "Kava pyrones and resin: studies on GABAA,GABAB and benzodiazepine binding sites in rodent brain" Pharmacology & Toxicology, 1992, 71, 120-126)

Dodd PR, *Williams SH, Gundlach AL, *Harper PAW, *Healy PJ, *Dennis JA and Johnston GAR "The glutamate and GABA neurotransmitter systems in the acute phase of maple syrup urine disease and citrullinaemia encephalopathies in newborn calves" J.Neurochem., 1992, 59, 582-590)

Johnston GAR "GABAA agonists as targets for drug development" Clinical and Experimental Pharmacology and Physiology, 1992, 19, 73-78

Johnston GAR and Akinci MK "Stress-induced changes inGABAA binding sites" Molecular Neuropharmacology,1992, 2, 151-154


Allan RD, Dickenson HW, Duke RK and Johnston GAR "ZAPA, a substrate for the neuronal high affinity GABA uptake system in ratbrain slices" Neurochemistry International, 1991, 18,63-67

Burden PM, Capper HR, Allan RD and Johnston GAR "The synthesis of1,8-disubstituted 10,11-dihydrodibenz-[b,f]oxepin-10-ones.Analogues of anaesthetic steroids" J. Chem. Soc. Perkin Trans.1, 1991, 3291-3294

Fletcher EJ and Johnston GAR "Regional heterogeneity of L-glutamate and L-aspartate high affinity uptake systems in the ratCNS" J. Neurochem., 1991, 57, 911-914

Fletcher EJ, Mewett KN, Drew CA, Allan RD and Johnston GAR "Inhibition of high affinity L-glutamic acid uptake into rat cortical synaptosomes by the conformationally restricted analogue of glutamic acid, cis-1-aminocyclobutane-1,3-dicarboxylic acid" Neuroscience Letters, 1991, 121, 133-135

Johnston GAR "GABAA antagonists" Seminars in the Neurosciences, 1991, 3, 205-210

Maddison JE, Watson WEJ, Dodd PR and Johnston GAR "Alterations incortical [3H]-kainate and[3H]-AMPA binding in a spontaneous animal model of chronic hepatic encephalopathy" J. Neurochem., 1991, 56, 1881-1888


Allan RD and Apostopoulos C "Synthesis of substituted(+)-bicuculline derivatives via chloromethylation" Australian Journal of Chemistry, 1990, 43, 1259-1268

Allan RD, Apostoloulos C and Richardson JA "2-Imino-1,3,4-thiadiazole derivatives of GABA as GABAAantagonists" Australian Journal of Chemistry, 1990, 43, 1767-1772

Allan RD, Bates MC, Drew CA, Duke RK, *Hambley TW, Johnston GAR,Mewett KN and Spence I "A new synthesis, resolution and invitro activities of (R)- and (S)-beta-phenyl-GABA" Tetrahedron, 1990, 46, 2511-2524

Allan RD, Drew CA, Ong J and Tran HW "Thioether analogues ofb aclofen, phaclofen and saclofen" Neuroscience Letters, 1990, 112, 223-228

Allan RD, Hanrahan JR, **Hambley TW, Johnston GAR, Mewett KN and Mitrovic AD "Synthesis and activity of a potentN-methyl-D-aspartic acid agonist,trans--1-aminocyclobutane-1,3-dicarboxylic acid, and related phosphonic and carboxylic acids" Journal of Medicinal Chemistry, 1990, 33, 2905-2915

Allan RD and Tran HW "Facile synthesis of beta-phenylethylamine derivatives related to baclofen via aziridine ring opening" Australian Journal of Chemistry, 1990, 43,1123-1127

Bolden SW, Hambley JW, Johnston GAR and Rogers LJ "Neonatal stress and long-term modulation of GABA receptors in rat brain" Neuroscience Letters, 1990, 111, 258-262

Dickenson HW, Duke RK, Balcar VJ, Allan RD and Johnston GAR "Binding to rat brain membranes of(+)-trans-(1S,3S)-3-aminocyclopentane-1-carboxylic acid,(+)-TACP, a selective GABA-A receptor agonist" MolecularNeuropharmacology, 1990, 1, 1-6)

Drew CA, Spence I and Johnston GAR "Effect of chronic exposure tol ead on GABA binding in developing rat brain" NeurochemistryInternational, 1990, 17, 43-51

Drew CA, Johnston GAR, Kerr DIB and Ong J "Inhibition of baclofen binding to rat cerebellar membranes by phaclofen, saclofen,3-aminopropylphosphinic acid and related GABA-A receptor antagonists" Neuroscience Letters, 1990, 113, 107-110

Gundlach AL, Grabara CSG, Johnston GAR and Harper PAW "Receptor alterations associated with spinal motoneuron degeneration in bovine Akabane disease" Annals of Neurology, 1990, 27, 513-519)

Huang JH and Johnston GAR "(+)-Hydrastine, a potent competitive antagonist at mammalian GABA-A receptors" Brit. J. Pharmac.,1990, 99, 727-730

Johnston GAR "Anxiety, steroids and GABA receptors" inAnxiety, N. McNaughton and G. Andrews, eds, University of Otago Press, Dunedin, 1990, pp. 201-212)

Johnston GAR "Anxiety chemistry" Chemistry in Australia,1990, 57, 334-337; reprinted in Australian Chemistry Resource Book, 1991, 10, 15-21

Kerr DIB, Ong J and Johnston GAR "Stress and cortisol modulation of GABA receptors" Stress & Anxiety, 1990, 13,209-213

Lummis SCR, Gundlach AL, Johnston GAR, Harper PAW and Dodd PR "Increased GABA receptor function in cerebral cortex of calves witha n inherited deficit of spinal glycine/strychnine receptors" J. Neurochem., 1990, 55, 421-426

Maddison JE, Leong DK, Dodd PR and Johnston GAR "Plasma GABA-like activity in rats with hepatic encephalopathy is due to GABA and taurine" Hepatology, 1990, 11, 105-110

Ong J, Harrison NL, Hall RG, Barker JL, Johnston GAR and Kerr DIB "3-Aminopropanephosphinic acid is a potent agonist at peripheral and central presynaptic GABA-B receptors" Brain Research, 1990, 526, 138-142)

Ong J, Kerr DIB, Capper HR and Johnston GAR "Cortisone, a potent GABA-A antagonist in the guinea-pig isolated ileum" J. Pharm.Pharmacol., 1990, 42, 662-664)

Ong J, Kerr DIB, Johnston GAR and Hall RG "Differing actions of baclofen and 3-amino-propylphosphinic acid in rat neocortical slices" Neuroscience Letters, 1990, 109, 169-173

Ong J, Kerr DIB and Johnston GAR "Effects of potassium channel blockers on baclofen-induced suppression of paroxysmal discharges inrat neo-cortical slices" Neuroscience Letters, 1990, 112, 216-222