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Publications: 2000

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Book chapters

  1. Johnston GAR (2000) 'GABA Chemistry: Analogs of GABA as therapeutic and investigational agents', in GABA in the Nervous System: The View at Fifty Years, Edited by David L. Martin and Richard W. Olsen, Lippincott Williams & Wilkins Publishers, Philadelphia, PA, USA, 65-80
  2. Johnston GAR, Chebib M, Duke RK (2000) 'Ionotropic GABA receptors: ligand gated ion channels' in Control and Diseases of Sodium Dependent Transport Proteins and Ion Channels, Edited by Y Suketa, E Carafoli, M Lazdunski, K Mikoshiba, Y Okada and EM Wright, Elsevier Science, Amsterdam, The Netherlands, pp. 369-372
  3. Maddison, J E. Adverse Drug Reactions. In textbook of Veterinary Internal Medicine, 5th ed. Ettinger, S.J. and Feldman, E.C.(eds). (2000) Saunders, Philadelphia pp. 320-325
  4. Maddison, J.E. Hepatic Encephalopathy. In: The Five Minute Consult, 2nd ed. Tilley, L.P and Smith, F.W.K (eds), Williams and Wilkins. (2000)
  5. Mylecharane E J and *Tfelt-Hansen P (2000) Nonsteroidal Antiinflammatory and Miscellaneous Drugs in Migraine Prophylaxis. In: The Headaches, *Olesen J, *Tfelt-Hansen P, *Welch KMA eds, 2nd edition, Lippincott Williams Wilkins, Philadelphia, pp. 489-498
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Refereed journal articles

  1. Ammit AJ, **Armour CL and Black JL (2000) Smooth-muscle myosin light-chain kinase content is increased in human sensitized airways, American Journal of Respiratory & Critical Care Medicine, 161, 257-263
  2. Aubrey KR, Mitrovic AD and Vandenberg RJ (2000) Molecular basis for proton regulation of glycine transport by glycine transporter subtype 1b. Molecular Pharmacology, 58, 129-135
  3. *Bajorek BV, *Krass I, *Ogle S, *Duguid M and Shenfield GM (2000) Antithrombotic prescribing in elderly patients with atrial fibrillation, Aust J Pharm, April , 81, 370
  4. Black JL and Johnson PRA (2000) What determines asthma phenotype? Is it the interaction between allergy and the smooth muscle? American Journal of Respiratory & Critical Care Medicine, 161(3Suppl S):S207-S210
  5. Burden PM, Ai TH, Lin HQ, Akinci M, Costandi M, **Hambley TM and Johnston GAR (2000) Chiral derivatives of 2-cyclohexylideneperhydro-4,7-methanoindenes, a novel class of nonsteroidal androgen receptor ligand. Synthesis, X-ray analysis and biological activity. Journal of Medicinal Chemistry, 2000, 43, 4629-4635
  6. Burgess JK and *Hazelton RH (2000) New developments in the analysis of gene expression, Redox Report, Vol.5, Nos 2/3, 2000
  7. Carlin S, **Poronnik P, **Cook DI, **Carpenter L, **Biden T, Johnson PRA and Black JL (2000) An antisense of protein kinase C-x inhibits proliferation of human airway smooth muscle cells. American Journal of Respiratory Cell and Molecular Biology 23, 555-559
  8. Chebib M and Johnston GAR (2000) 'GABA-activated ligand gated ion channels: medicinal chemistry and molecular biology', Journal of Medicinal Chemistry, 43, 1427-1447
  9. Chebib M and *Quinn RJ, '1-Phenylpyrazolo[3,4-d]pyrimidines: Structure-activity relationships for C6 substituents at A1 and A2a Adenosine receptors' Bioorganic and Medicinal Chemistry, accepted 1.7.99
  10. Christie MJ, Connor M, Vaughan CW, Ingram SL and Bagley EE (2000) Cellular actions of opioids and other analgesics: implications for synergism in pain relief, Clinical and Experimental Pharmacology and Physiology, 27, 520-523
  11. *Clarke SJ, *Beale PJ and Rivory LP (2000) Clinical and preclinical pharmacokinetics of raltitrexed. Clinicial Pharmacokinetics, 39, 429-443
  12. Dodds HM, Clarke SJ, Findlay M, Bishop JF, JRobert J and Rivory LP (2000) Clinical Pharmacokinetics of the irinotecan metabolite 4-piperidinopiperidine and its possible clinical importance. Cancer Chemother Pharmacol 45, 9-14
  13. Duke RK, Chebib M, **Balcar VJ, Allan RD, Mewett KN and Johnston GAR (2000) (+)- and (-)-cis-2-Aminomethylcyclopropanecarboxylic acid show opposite pharmacology at recombinant r1 and r2 GABAC receptors. Journal of Neurochemistry, 75, 2602-2610)
  14. **Dutton JL, **Poronnik P, **Li GH, **Holding CA, **Worthington RA, Vandenberg RJ, **Cook DI, **Barden JA and **Bennett MR (2000) P2X(1) receptor membrane redistribution and down-regulation visualized by using receptor-coupled green fluorescent protein chimeras, Neuropharmacology, 39, 2054-2066
  15. *Foe K, **Brown KF and Seale JP (2000) Comparative kinetics of metabolism of beclomethasone propionate esters in human lung homogenates and plasma. Journal of Pharmaceutical Sciences, 89, 1143-1150
  16. **Foe K, **Cutler DJ,**Brown KF and Seale JP (2000) Metabolism kinetics of beclomethasone propionate esters in human lung homogenates. Pharmaceutical Research, 17, 1007-1012
  17. *Ford TW, Vaughan CW and *Kirkwood PA (2000) Changes in the distribution of synaptic potentials from bulbospinal neurones following axotomy in cat thoracic spinal cord. Journal of Physiology (London), 524, 163-178
  18. **Hambley TW, *Knott R, Kassiou M. & Christie MJ (2000) X-ray Crystallographic Structures of Biologically Active Trishomocubanes of the Types Pentacyclo[5.4.0.02,6.03,10.05,9]undecylamines and 4 Azahexacyclo [5.4.1.02,6.03,10.05,9.08,11] dodecane. Aust J Chem. 53, 899-904
  19. **Hughes JM, **Arthur CA, **Baracho S, Carlin SM, Hawker KM. Johnson PRA and **Armour CL (2000) Human eosinophil-airway smooth muscle cell interactions. Mediators of Inflammation, 9, 93-99
  20. Johnson PRA, Black JL, Carlin S and *Underwood PA (2000) The production of extracellular matrix proteins by human passively sensitized airway smooth muscle cells in culture-the effect of beclomethasone. American J Resp Crit Care Med, 162, 2145-2151
  21. Kassiou M, *Loc'h C, *Katsifis A, *Papazian V, *Mattner F, *Dikic B and *Maziere B (2000) Radiosynthesis of Bromine-76 and Iodine-123 Labelled Enantiomers of A-69024: Radioligands for Dopamine D1 Receptor Studies Using PET and SPECT. Journal of Labelled Compounds and Radiopharmaceuticals, 43, 339-346
  22. Lee J-H, Johnson PRA, Roth M, **Hunt NH and Black JL (2000) Extracellular signal regulated protein kinase activation and mitogen-induced cell proliferation in human airway smooth muscle cells. American Journal of Physiology: Lung Cell Mol. Physiol. (in press)
  23. *Li Y, *Wood N, Grimsley P, *Yellowlees D and Donelly PK (2000) In vitro invasiveness of human breast cancer cells is promoted by low density lipoprotein receptor-related protein, Invasion Metastasis, 18, 240-251
  24. **Lieb I, Chebib M, **Cooper B, **Dias LS and **Balcar VJ (2000) Quantitative Autoradiography of Na+-dependent [3H]L-aspartate binding to L-glutamate transporters in rat brain: Structure-activity studies using L-trans-pyrrolidine-2,4-dicarboxylate (L-t-PDC) and 2-(Carboxycyclopropyl)-glycine (CCG)', Neurochemistry International, 36, 319-327
  25. Maddison JE (2000) Newest insights into hepatic encephalopathy. European Journal of Comparative Gastroenterology, 5, 17-21
  26. **McKay KO, Johnson PRA, Black JL and **Armour CL (2000) Parasympathetic neurotransmission in rabbit isolatedbronchus is modulated at prejunctional sites via endothelinB receptor stimulation, Respirology, 5, 343-353
  27. McParland B, Johnson PRA. **Armour CL and Black JL (2000) An epithelial derived factor inhibits contraction in canine perfused bronchial segments, European Journal of Pharmacology, 402, 51-159
  28. *Meikle SR, *Eberl S, *Fulton RR, Kassiou M and *Fulham MJ (2000) The Influence of Tomograph Sensitivity on Kinetic Parameter Estimates in Small Animal Imaging Studies. Nuclear Medicine and Biology, 27, 617-625
  29. **Minto C, **Li B, **Tattam B, **Brown K, Seale JP and Donnelly R (2000) Pharmacokinetics of epimeric budesonide and fluticasone propionate after repeat dose inhalation &endash; intersubject variability in systemic absorption from the lung, British Journal of Clinical Pharmacology, 50, 116-124
  30. *Moore LB, *Parks DJ, *Jones SA, *Goodwin BJ, Liddle C, *Wilson TM, *Collins JL and *Kliewer SA (2000) Orphan nuclear receptors CAR and PXR share xenobiotic and steroid ligands, Journal of Biological Chemistry, 275, 15122-15127
  31. *Osborne PB, Chieng B and Christie MJ (2000) Morphine-6 beta-glucuronide has a higher efficacy than morphine as a mu-opioid receptor agonist in the rat locus coeruleus, British Journal of Pharmacology, 131, 1422-1428
  32. Patiag D, Qu X, *Gray S, *Idris I, Wilkes M, Seale JP and Donnelly R (2000) Possible interactions between angiotensin II and insulin: effects on glucose and lipid metabolism in vivo and in vitro. Journal of Endocrinology, 167, 525-531 2000
  33. Rivory LP, Slaviero K, Seale JP, Hoskins JM, Boyer M, Beale PJ, Millward MJ, Bishop JF and Clarke SJ (2000) Optimizing the erythromycin breath test for use in cancer patients. Clinical Cancer Research, 6, 3480-3485
  34. **Seeto C, **Namkung-Matthai H, **Jayram S, **Foe K, **Brown KF, **Hughes JM, **Mason RS, **Armour CL and Seale JP (2000) Differential potency of beclomethasone esters in-vitro on human T-lymphocyte cytokine production and osteoblast activity, Journal of Pharmacy and Pharmacology, 52, 417-423
  35. Stasinopoulos T, **Goodchild AK, Christie MJ, **Chalmers J and **Pilowsky PM (2000) Delta opioid receptor immunoreactivity boutons appose bulbospinal C1 neurons in the rat. NeuroReport, 11, 887-891
  36. **Sukkar MB, **Hughes JM, Johnson PR and **Armour CL (2000) GM-CSF production from human airway smooth muscle cells is potentiated by human serum. Mediators of Inflamation, 9, 161-168
  37. *Szeto TH, *Wang XH, *Smith RW, Connor MA, Christie MJ, *Nicholson GM and **King GF (2000) Isolation of a funnel-web spider polypeptide with homology to mamba intestinal toxin 1 and the embryonic head inducer Dickkopf-1. Toxicon, 38, 429-442
  38. *Szeto TH, *Binnyi-Strachan LC, *Smith RW, Connor MA, Christie MJ, **King GF and*Nicholson GM (2000) Isolation and pharmacological characterisation of delta-atracotoxin-Hv 1b, a vertebrate-selective sodium channel toxin. FEBS Letters, 470, 293-299
  39. Vaughan CW, Connor M, Bagley EE and Christie MJ (2000) Actions of cannabinoids on membrane properties and synaptic transmission in rat periaquedutal gray neuones in vitro, Molecular Pahrmacology, 57, 288-295
  40. Vaughan CW and Christie MJ (2000) An analgesic role for cannabinoids, Medical Journal of Australia, 173(5), 270-272
  41. *Wang XH, Connor M, *Smith R, Maciejewski MW, *Howden MEH, *Nicholson GM, Christie MJ and **King GF (2000) Discovery and characterization of a family of insecticidal neurotoxins with a rare vicinal disulfide bridge. Nature Structural Biology, 7, 505-513
  42. Yap EYS, *Battistini B and McKay KO (2000) Contraction to big entothelin-1, big endothelin-2 and big-endothelin-3, and endothelin-converting enzyme inhibition in human isolated bronchi, British Journal of Pharmacology, 129, 170-176
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Journal articles published electronically

  1. *Kossoff G and Johnston GAR, "Report on the 13th Convocation of the Council of Academies of Engineering and Technological Sciences on 'Technology and Health'" Sophia-Antipolis, France, 24-28 May 1999. Convened by the Australian Academy of Technological Sciences and Engineering
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Other publications

  1. Duke RK, **Duke CC, Johnston GAR and **Roufogalis BD 'Gingko biloba: living fossil with modern applications' Australian Pharmacy Trade, p 26, 15 June 2000
  2. Farrar N, 'New drug balances the diabetic see-saw' Australasian Science, 2000, 21(9), 30-31
  3. *Grace RF, Shenfield GM and *Tennant C (2000) Cannabis and psychosis in acute psychiatric admissions, Drug and Alcohol Review 19, 289- 292
  4. Johnston GAR 'The medicinal chemistry-molecular biology interface: recombinant receptors in the search for new drugs' in Technology & Health, Proceedings of the 13th Convocation of the Council of Academies of Engineering and Technological Sciences, ISBN 2-7430-0386-3, Paris, France, 2000, pp 72-74
  5. Johnston GAR 'Smart Drugs: Threat or Promise?' Australasian Science, 2000, 21(10), 26-27
  6. *Montague RE, *Ogle SJ and Shenfield GM 'Deliberate overdose in the elderly' Medical Journal of Australia. 2000, 173(3), 164
  7. *Pearson S, *Smith AJ, *Rolfe IE, *Moulds FR and G M Shenfield GM (2000), Intern Prescribing for Common Clinical Conditions, Advances in Health Sciences Education, 5, 141 - 150
  8. Shenfield GM (2000) The Biter Bitten Lancet 355, 666
  9. Shenfield GM (2000) The Glitazones, New Medications for Type 2 Diabetes, Diabetes Conquest, Winter 2000, 10-11
  10. Shenfield GM (2000) Injury is the Best Defence, Lancet 356, 1780
  11. Shenfield GM (2000) Triple Jeopardy, Medicine Today. Feb, 136-137
  12. Shenfield GM (2000) Trust Me I'm A Doctor, The Skeptic, 20(4) 42-46
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NOTE:
**Member of another department, University of Sydney
*Not a member of the University of Sydney