Discipline of Physiology
The Discipline of Physiology is part of the School of Medical Sciences and is the focus of teaching and research in the physiological sciences at The University of Sydney.
Its research staff and students are located primarily at the Camperdown Campus of the University, in the Anderson Stuart Building and in the Medical Foundation Building. Academics in the discipline teach undergraduate programs in the Faculty of Science, and the Graduate Medical Program.
The research interests of the faculty span a broad range of topics in the physiological sciences, with particular research focus on neuroscience, cardiovascular physiology, reproductive physiology, and endocrine function. Techniques used in our laboratories include imaging, electrophysiology, molecular biology, and human and animal behaviour.
Movember Foundation and the Prostate Cancer Foundation of Australia Grant
An International, multidisciplinary team has been awarded $3.25M over 3 years from the Movember Foundation and the Prostate Cancer Foundation of Australia (PCFA). Led by A/Prof Lisa Butler in Adelaide and including Dr Andrew Hoy, the project will address one of the most urgent needs in prostate cancer management – the ability to distinguish, at the time of diagnosis, between patients with significant life-threatening cancer, and those with organ-confined cancer that may not need to be treated at all. The project will focus on lipids in prostate tumours as a completely new way of predicting the cancer’s future behaviour. The aim is to identify a specific signature of lipids that can be readily detected in the tumour tissue, using state-of-the-art imaging, to help determine which tumours are more likely to spread aggressively through the body.
Dr Hoy will be leading the investigation into the link between obesity and prostate cancer. Currently, a link exists between obesity and the incidence of prostate cancer. Additionally, obesity influences lipid metabolism in prostate cancer. This project will also help to better understand the role of altered lipid metabolism and prostate cancer biology and disease progression, the role of exogenous fatty acids (dietary and from fat stores), and therefore the potential modifying role of obesity in disease and treatment.
Movember Revolutionary Team Chief Investigators L to R: Dr Andrew Hoy, Prof Gary Wittert, A/Prof Lisa Butler, Prof Andrew Scott, Prof Wayne Tilley, Prof Johannes Swinnen
- Associate Professor Lisa Butler (Team Leader) from the Uni of Adelaide’s Prostate Cancer Research Group, SAHMRI – Freemasons Foundation Centre for Men’s Health
- Professor Wayne Tilley from the Uni of Adelaide’s Adelaide Prostate Cancer Research Centre, Dame Roma Mitchell Cancer Research Laboratories, Freemasons Foundation Centre for Men’s Health
- Professor Gary Wittert, University of Adelaide, Freemasons Foundation Centre for Men’s Health
- Professor Andrew Scott, The Ludwig Institute for Cancer Research in Melbourne
- Dr Andrew Hoy, the University of Sydney
- Professor Johannes Swinnen, the University of Leuven, Belgium