Innovations in medical physics to improve human health.
Goal: The scientific goal is an improved understanding of macroscopic and microscopic response of cancerous and normal tissue to radiation. The clinical goal is to translate more accurate radiation-tumor targeting into improved cancer therapy success through higher local tumor control with decreased treatment-related toxicity and reduced metastatic spread. more
The Australian MRI-linac Program: Improving cancer treatment through real-time image guided radiotherapy.
CIs: Keall, Barton, Crozier
Goal: To develop MRI technology to improve the way in which cancer can be tracked as it moves within the body, assisting in improving the effectiveness of radiation therapy. more
Respiratory motion-guided 4D cone beam CT imaging.
Goal: More advanced image guidance methods are being implemented in radiation therapy. These advances facilitate shaping the radiation beam to the anatomically changing tumour during a course of treatment. More accurate targeting facilitates increased survival and reduces treatment-related toxicities for cancer patients. In this project we will develop and investigate our research innovation and create 2nd generation ‘respirator modulated’ 4D cone beam CT to allow the improved visualization of lung tumours at the time of treatment. more
A hybrid magnetic resonance imaging: linear accelerator for highly accurate radiotherapy cancer treatment.
CI: Crozier, Keall
Goal: Radiotherapy is often used to treat cancer, however it is very difficult to ensure the radiation doses the tumour properly as the tumour moves during treatment due to breathing, etc. This project will produce an image-guidance system that will allow much better targeting of the treatment and thus produce better outcomes. more
An adaptable and dedicated linear accelerator for medical radiation research.
CIs: Keall, Jackson, Rozenfeld, Barton, Greer, Vial, Baldock, Meltcalfe, Thwaites, Kuncic, Holloway, Bosi, Eslick, Downes
Goal: Leading radiation scientists developing innovative methods and devices for treating cancer patients will collaborate in future research using an adaptable and dedicated linear accelerator for medical radiation research. Innovations in tumour targeting, better patient safety, new medical devices and improved cancer outcomes are expected. more
Treating deforming tumours with real-time adaptive radiotherapy
Goal: To develop an internationally unique radiotherapy system that can adjust the radiation beam in real time to follow the changing tumour shape. more
4D IMRT: Integrated Imaging, Planning and Delivery.
CIs: Keall, Loo
Goal: To solve the general 4D planning problem and develop methods to locate and target moving tumors for lung stereotactic body radiotherapy. more
Real-time tumour tracking with beam's-eye-view-imaging.
CIs: Berbeco, Keall
Goal: The major goal of this project is to develop methods and investigate the hypothesis that tracking lung tumors directly during SBRT, using beam’s-eye-view (BEV) imaging coupled with a dynamic multileaf collimator (DMLC), will lead to clinically significant normal tissue sparing. more